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xanthogranuloma

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https://www.readbyqxmd.com/read/29057365/a-rare-case-of-intramedullary-solitary-juvenile-xanthogranuloma-of-the-lumbar-spine-in-the-adult-a-case-report
#1
Vania Pirillo, Andrea Prontera, Paolo Rizzo, Paolo Cipriano Cecchi, Martin Maffei, Andreas Schwarz
Solitary juvenile xanthogranuloma (SJX) of the spine is an extremely rare proliferative histiocytic disorder with only few cases reported in literature. We present the first case of intramedullary spinal SJX. A 22-year-old male presented with a nine-month history of progressively worsening sphincteric disturbances and saddle hypoesthesia. Magnetic resonance imaging showed an intra-axial lesion located in the conus medullaris; T1 hypointense, T2 iso-hyperintense and uniformly enhancing after contrast administration...
September 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29048134/necrobiotic-xanthogranuloma-treated-with-lenalidomide
#2
P Mahendran, J Wee, H Chong, J Natkunarajah
No abstract text is available yet for this article.
October 19, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29042820/necrobiotic-xanthogranuloma-scleritis-in-a-case-of-granulomatosis-with-polyangiitis-wegener-s-granulomatosis
#3
Narumon Keorochana, Kanaspana Klanarongran, Kantang Satayasoontorn, Sumapa Chaiamnuay
The purpose of this study was to describe a case of necrobiotic xanthogranuloma scleritis in a 53-year-old male with unilateral progressive visual loss, scleritis, prolonged fever, and multiple mononeuropathy. Scleral biopsy showed necrosis with small abscess, and the pathological tissues revealed submucosal infiltration of mononucleated foamy histiocytes (xanthoma cells), hemosiderin-laden macrophages, neutrophils, lymphocytes, plasma cells, and erythrocytes without Touton giant cells or cholesterol clefts...
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/28994877/xanthogranuloma-of-the-sellar-region
#4
Alia Zehani, Yoldez Houcine, Ines Chelly, Hafedh Jemel, Slim Haouet
No abstract text is available yet for this article.
November 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/28965734/scalp-lesions-in-a-pediatric-patient-with-hyper-igm-syndrome-clinical-and-histologic-mimicry-of-cryptococcus-neoformans-infection
#5
Karen P Acker, Audrey Fetch, Stephanie A Schnell, Jennifer Hammond, Christina Herrera, George Niedt, Adam J Ratner, Christine T Lauren
We report a case of cutaneous cryptococcosis due to Cryptococcus neoformans in a pediatric patient with hyper IgM syndrome with scalp lesions that resembled tinea capitis on gross examination and mimicked juvenile xanthogranuloma on histologic examination. This case highlights the importance of considering cutaneous cryptococcosis in patients with hyper IgM syndrome.
September 28, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28960169/systemic-juvenile-xanthogranuloma-a-case-of-spontaneous-regression-of-intramedullary-spinal-cord-cerebral-and-cutaneous-lesions
#6
Anne Morice, Sylvie Fraitag, Catherine Miquel, Christian Sainte Rose, Stéphanie Puget
Juvenile xanthogranuloma (JXG) is a rare disease that belongs to the non-Langerhans cell histiocytoses. It presents a wide clinical spectrum, usually occurs before 5 years of age, and is commonly confined to the skin; however, it can affect multiple sites, including the nervous system, and can lead to severe disorders. Although JXG is a benign disease that usually regresses spontaneously, several curative treatments have been proposed in cases of organ involvement. Treatment options include corticosteroids, chemotherapy, and radiotherapy; however, these can have severe, long-term adverse effects in children...
September 29, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28948701/hepatobiliary-and-pancreatic-hepatic-necrobiotic-xanthogranuloma
#7
B D Nguyen
No abstract text is available yet for this article.
October 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28936088/symptomatic-bilateral-xanthogranuloma-of-the-choroid-plexus
#8
Selin Tural Emon, Erek Ozturk, Kaan Meric, Fugen Aker, Metin Orakdogen
Xanthogranulomas (XGRs) of the choroid plexus are rare, asymptomatic, and benign lesions usually found incidentally. Here, we present a case of a 47-year-old male with bilateral XGR of the choroid plexus with periventricular edema and discuss our case in relation to a review of existing literature pertaining to the radiology of XGRs. To the best of our knowledge, this is the first reported case of bilateral trigonal XGR causing brain edema without ventricular dilatation. Despite the fact that they can cause hydrocephalus, XGRs are silent and benign lesions...
August 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28920477/if-it-looks-like-a-xanthogranuloma-and-walks-like-a-xanthogranuloma
#9
Paul B Medline
No abstract text is available yet for this article.
September 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28920472/it-may-look-similar-to-a-xanthogranuloma-under-the-microscope-but-it-does-not-really-walk-like-one-clinically
#10
Sate Hamza, Alexandra Kuzyk, Shane Silver, Sharon Wallace, John Toole
No abstract text is available yet for this article.
September 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28875110/monomorphic-xanthomatous-type-of-xanthogranuloma-a-rare-entity
#11
Pratheeba Devi Nivean, M Nivean
Xanthogranuloma is an uncommon tumor in the ocular adnexa. It usually presents as diffuse lid swelling with or without orbital involvement. Xanthogranulomas can be associated with systemic comorbidities. They are diagnosed by their characteristic pathological finding. They are further subclassified based on immunohistochemistry. We present two cases with lid swelling which were diagnosed to be xanthogranuloma. Our cases were special because of the unique presentation as localized monomorphic lesions.
2017: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/28871936/xanthoma-like-skin-changes-in-an-elderly-woman-with-a-normal-lipid-profile
#12
Piotr Nockowski, Zdzisław Woźniak, Adam Reich, Joanna Maj
Dear Editor, An 83-year-old woman developed yellow-brownish infiltrates, nodules, and tumors mimicking xanthomas, mostly involving the periorbital and chest area within three months (Figure 1). She had no abnormalities in serum cholesterol or triglycerides levels. A detailed laboratory analysis revealed the presence of mild monoclonal gammopathy with a presence of immunoglobulin G (IgG) kappa light chains; however, according to hematologist consultation, it did not require medical intervention. Imaging assessment and ultrasound examination did not show any specific involvement of internal organs...
July 2017: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/28863117/rituximab-monotherapy-is-effective-in-treating-orbital-necrobiotic-xanthogranuloma
#13
Oded Sagiv, Sudip D Thakar, Gail Morrell, Michael T Tetzlaff, Bita Esmaeli
The authors report a case of a patient with bilateral orbital necrobiotic xanthogranuloma and no associated systemic paraproteinemia. Orbital biopsy showed strong expression of CD20-positive cells. The patient was treated with systemic rituximab monotherapy, with excellent clinical response and marked regression of the orbital lesions on imaging. At the time of writing, the patient has been treated with bimonthly rituximab maintenance therapy for 22 months and has stable clinical and imaging findings with sustained response to treatment and no reported side effects...
August 23, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28836893/systemic-juvenile-xanthogranuloma-involving-the-bone-marrow-multiple-bones-and-the-skin-that-developed-during-treatment-of-acute-lymphoblastic-leukemia-in-remission-state
#14
Eunjae Cheon, Saemi Yang, Jae Ho Han, Kwang Chul Lee, Jun Eun Park
Juvenile xanthogranuloma (JXG) is a rare benign disorder classified as non-Langerhans cell histiocytosis, with unclear etiology and pathogenesis. JXG is generally characterized by solitary or multiple cutaneous nodules that resolve spontaneously over a few years. JXG rarely presents as extracutaneous lesions that progress to a symptomatic systemic disorder through multiple organ involvement. We encountered a systemic JXG case involving the bone marrow, multiple bones, and the skin during acute lymphoblastic leukemia treatment...
January 1, 2017: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/28816552/the-role-of-biopsy-in-lacrimal-gland-inflammation-a-clinicopathologic-study
#15
Panitee Luemsamran, Jack Rootman, Valerie A White, Nariman Nassiri, Manraj K S Heran
PURPOSE: To determine the causes of lacrimal gland inflammation based on histopathology and systemic evaluation. METHODS: This is a retrospective case series study. From the University of British Columbia Orbit Clinic between January 1976 and December 2008, we reviewed the medical records of 60 patients who presented with inflammatory features of the lacrimal gland (i.e., erythema, edema, or tenderness) in which the diagnoses were not possible clinically and on imaging alone...
August 17, 2017: Orbit
https://www.readbyqxmd.com/read/28802503/fibrohistiocytic-tumors
#16
REVIEW
Ryan C Romano, Karen J Fritchie
Fibrohistiocytic tumors are a diverse group of reactive and neoplastic lesions including xanthoma, fibrous histiocytoma and its variants, solitary xanthogranuloma, dermatofibrosarcoma protuberans, and atypical fibroxanthoma. This article reviews some of the more commonly encountered fibrohistiocytic tumors with an emphasis on clinical presentation, macroscopic and histologic characteristics, molecular/cytogenetic findings where applicable, and differential diagnoses.
September 2017: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/28752840/genetic-evaluation-of-juvenile-xanthogranuloma-genomic-abnormalities-are-uncommon-in-solitary-lesions-advanced-cases-may-show-more-complexity
#17
Christian N Paxton, Dennis P O'Malley, Andrew M Bellizzi, Deema Alkapalan, Yuri Fedoriw, Jason L Hornick, Sherrie L Perkins, Sarah T South, Erica F Andersen
Juvenile xanthogranuloma is a rare histiocytic proliferation primarily affecting infants and young children, characterized by aberrant infiltration of histiocyte-derived cells in the skin, soft tissues and more rarely, visceral organs. Juvenile xanthogranuloma is generally considered to be a benign disorder; most lesions are solitary cutaneous nodules that resolve spontaneously without treatment. However, cases with extracutaneous involvement, multiple lesions, and/or systemic disease often require aggressive therapy...
September 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28739622/an-unusual-case-of-interstitial-lung-disease-in-a-patient-with-cardiopulmonary-syndrome-as-the-initial-presentation-of-erdheim-chester-disease
#18
Domingo Franco-Palacios, April McDonald, R Neal Aguillard, Allen Berry
Erdheim-Chester disease (ECD) is a very rare disorder with only approximately 600 cases reported in the literature. ECD has been recently reclassified as a histiocytic dendritic cell neoplasm. The clinical spectrum ranges from asymptomatic tissue accumulation of histiocytes to invasive tissue infiltration, which can cause fulminant multisystem failure. It typically presents with bone pain and constitutional symptoms. Extraosseous manifestations are not uncommon. ECD-associated interstitial lung disease has been described in 20%-35% of patients...
July 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28671710/adult-xanthogranuloma-diagnosed-on-reflectance-confocal-microscopy
#19
LETTER
Attiya Haroon, Shahram Shafi, Babar Rao
No abstract text is available yet for this article.
September 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28626159/limbal-xanthogranuloma-in-a-dog
#20
Juri Ota-Kuroki, Keiichi Kuroki
A 10-year-old female spayed American Pitt Bull Terrier was presented with a slow growing mass on the temporal limbus area of the right eye. Canine nodular granulomatous episclerokeratitis was suspected, and the affected eye was treated with 1% prednisolone acetate ophthalmic suspension and 0.03% Tacrolimus ophthalmic solution. As the lesion did not respond to the medical treatments and continued to grow, the mass was excised by lamellar sclerokeratectomy. Microscopically, the mass was composed of granulomatous inflammation with intrahistiocytic lipids and lakes of acicular cholesterol clefts, histopathology findings consistent with xanthogranuloma...
July 19, 2017: Journal of Veterinary Medical Science
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