keyword
https://read.qxmd.com/read/38634392/glass-like-phonon-dynamics-and-thermal-transport-in-a-gete-nano-composite-at-low-temperature
#21
JOURNAL ARTICLE
R Cravero, A Tlili, J Paterson, M Tomelleri, P Marcello, R Debord, S Pailhès, O Bourgeois, F Hippert, D Le Qui, J-Y Raty, P Noe, V M Giordano
In this work, the experimental evidence of glass-like phonon dynamics and thermal conductivity in a nanocomposite made of GeTe and amorphous carbon is reported, which is of interest for microelectronics, and specifically phase change memories. It is shown that, the total thermal conductivity is reduced by a factor of three at room temperature with respect to pure GeTe, due to the reduction of both electronic and phononic contributions. This latter, similarly to glasses, is small and weakly increasing with temperature between 100 and 300 K, indicating a mostly diffusive thermal transport and reaching a value of 0...
April 18, 2024: Small
https://read.qxmd.com/read/38634319/solitary-isolated-oropharyngeal-neurofibroma-presenting-with-dysphagia-in-the-setting-of-von-recklinghausen-s-disease
#22
JOURNAL ARTICLE
Shrita Sarkar, Chandan Seth, Mainak Dutta, Saumendra Nath Bandyopadhyay
A 24-year-old man with von Recklinghausen's disease presented with complaints of difficulty in swallowing for 6 months and change of voice for 3 months. He also had recent-onset difficulty in breathing. Telelaryngoscopy and subsequent contrast-enhanced computed tomography scan revealed a well-defined, smooth submucosal mass in the oropharynx (attached to the posterior pharyngeal wall, superior to the level of left aryepiglottic fold), obscuring the ipsilateral pyriform fossa, and nearly blocking the pharyngeal lumen...
April 18, 2024: Ear, Nose, & Throat Journal
https://read.qxmd.com/read/38634188/a-type-proanthocyanidins-sources-structure-bioactivity-processing-nutrition-and-potential-applications
#23
JOURNAL ARTICLE
Yu Zeng, Lei Zhao, Kai Wang, Catherine M G C Renard, Carine Le Bourvellec, Zhuoyan Hu, Xuwei Liu
A-type proanthocyanidins (PAs) are a subgroup of PAs that differ from B-type PAs by the presence of an ether bond between two consecutive constitutive units. This additional C-O-C bond gives them a more stable and hydrophobic character. They are of increasing interest due to their potential multiple nutritional effects with low toxicity in food processing and supplement development. They have been identified in several plants. However, the role of A-type PAs, especially their complex polymeric form (degree of polymerization and linkage), has not been specifically discussed and explored...
May 2024: Comprehensive Reviews in Food Science and Food Safety
https://read.qxmd.com/read/38634178/molecular-level-insight-into-the-chlorofluorocarbons-adsorption-by-defective-covalent-organic-polymers
#24
JOURNAL ARTICLE
Jian Shen, Mohammad Wahiduzzaman, Abhishek Kumar, Dushyant Barpaga, B Peter McGrail, Praveen Thallapally, Guillaume Maurin, Radha Kishan Motkuri
Halocarbons have important industrial applications, however they contribute to global warming and the fact that they can cause ozone depletion. Hence, the techniques that can capture and recover the used halocarbons with energy efficiency methods have recently received greater attention. In this contribution, we report the capture of dichlorodifluoromethane (R12), which has high global warming and ozone depletion potential, using covalent organic polymers (COPs). The defect-engineered COPs were synthesized and demonstrated outstanding sorption capacities, ~226 wt% of R12 combined with linear-shaped adsorption isotherms...
April 17, 2024: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://read.qxmd.com/read/38634133/effect-of-the-dash-diet-on-the-sodium-chloride-cotransporter-and-aquaporin-2-in-urinary-extracellular-vesicles
#25
JOURNAL ARTICLE
Dana Bielopolski, Luca Musante, Ewout J Hoorn, Henrik Molina, Douglas Barrows, Thomas Carroll, Michael A Harding, Samantha Upson, Adam Qureshi, Max M Weder, Jonathan N Tobin, Rhonda G Kost, U Erdbrügger
The Dietary Approach to Stop Hypertension (DASH) diet, with its low sodium and high potassium content, acts like a diuretic by reducing sodium reabsorption in the kidney's distal convoluted tubule but without the side effects. Previous studies based on animal models didn't explore changes in human ion channel proteins. Recent insights into urinary extracellular vesicles (uEVs) suggest they reflect kidney tissue and physiological modifications. In our inpatient study, we shifted hypertensive volunteers from an American diet to the DASH diet, examining changes in those with stage 1 untreated hypertension...
April 18, 2024: American Journal of Physiology. Renal Physiology
https://read.qxmd.com/read/38634100/injury-mortality-of-children-and-adolescents-aged-0-19-years-china-2010-2021
#26
JOURNAL ARTICLE
Jingtao Zhou, Min Zhao, Hao Huang, David C Schwebel, Peishan Ning, Zhenzhen Rao, Peixia Cheng, Li Li, Guoqing Hu
INTRODUCTION: To examine the recent trends in child injury mortality in China. METHODS: Injury mortality data of 2010-2021 for children and adolescents aged 0-19 years were from the China Health Statistics Yearbook. Injury mortality disparities across urban vs. rural locations, gender, and age groups were scrutinized. Annual percent change (APC), average annual percent change (AAPC), and their 95% confidence intervals (95% CI ) were estiamted usimg Joinpoint regression models...
April 5, 2024: China CDC weekly
https://read.qxmd.com/read/38634036/influence-of-access-cavity-design-on-root-canal-instrumentation-efficacy-in-molars-an-in-vitro-study
#27
JOURNAL ARTICLE
Vedamani Chandolu, Jyothi Mandava, Roopesh Borugadda, Kantheti Sirisha, Konagala Ravi Kumar, Sameera Goteti, Lalitha Sri Roja Nallamilli
BACKGROUND: Several designs of access cavity have been evolved in the recent past with the concept of minimal tooth tissue removal which would improve the root canal treated teeth fracture resistance. AIM: To investigate the effect of conservative design access cavity during the instrumentation of maxillary molar root canals. MATERIALS AND METHODS: Eighty noncarious maxillary molars were assigned to the traditional and conservative access groups ( n = 40 each)...
March 2024: J Conserv Dent Endod
https://read.qxmd.com/read/38633797/incidence-and-risk-factors-of-omicron-variant-sars-cov-2-breakthrough-infection-among-vaccinated-and-boosted-individuals
#28
Fabiola M Moreno-Echevarria, Mathew T Caputo, Daniel M Camp, Susheel Reddy, Chad J Achenbach
BACKGROUND: SARS-CoV-2 vaccines have been shown to be safe and effective against infection and severe COVID-19 disease worldwide. Certain co-morbid conditions cause immune dysfunction and may reduce immune response to vaccination. In contrast, those with co-morbidities may practice infection prevention strategies. Thus, the real-world clinical impact of co-morbidities on SARS-CoV-2 infection in the recent post-vaccination period is not well established. We performed this study to understand the epidemiology of Omicron breakthrough infection and evaluate associations with number of comorbidities in a vaccinated and boosted population...
April 5, 2024: medRxiv
https://read.qxmd.com/read/38633620/differential-susceptibility-to-propofol-and-ketamine-in-primary-cultures-of-young-and-senesced-astrocytes
#29
JOURNAL ARTICLE
Liang Huang, Ferit Tuzer, Abigail Murtha, Michael Green, Claudio Torres, Henry Liu, Shadi Malaeb
The adverse effects of general anesthesia on the long-term cognition of young children and senior adults have become of concern in recent years. Previously, mechanistic and pathogenic investigations focused on neurons, and little is known about the effect of commonly used intravenous anesthetics such as propofol and ketamine on astrocytes. Recently, astrocyte dysfunction has been implicated in a wide range of age-related brain diseases. In this study, we examined the survival and viability of both young and senescent astrocytes in culture after adding propofol and ketamine to the media at varying strengths...
2024: Anesthesiology Research and Practice
https://read.qxmd.com/read/38633565/correlation-between-hif1-a-expression-and-airway-remodeling-in-copd
#30
JOURNAL ARTICLE
Lingfang Tan, Xuefeng Yang, Jianxin Zhang, Kebing Zhou
BACKGROUND: Airway remodeling is a significant pathological characteristic of chronic obstructive pulmonary disease (COPD). In recent years, hypoxia-inducible factor 1-α (HIF-1α), a member of the hypoxia-inducible factor protein family, has gained attention. However, the potential correlation between HIF-1α and COPD airway remodeling remains unclear. OBJECTIVE: This study explored the expression patterns of HIF-1α in patients with COPD and its association with airway remodelling...
2024: International Journal of Chronic Obstructive Pulmonary Disease
https://read.qxmd.com/read/38633522/historical-changes-in-the-distribution-of-the-sichuan-golden-snub-nosed-monkey-rhinopithecus-roxellana-in-sichuan-province-china
#31
JOURNAL ARTICLE
Yunchuan Dai, Wancai Xia, Yujing Zhu, Charlotte Hacker, Xueyu Wang, Dayong Li
The Sichuan golden snub-nosed monkey ( Rhinopithecus roxellana ) is a rare and endangered primate species endemic to China. Conducting research on the population distribution changes of the Sichuan golden snub-nosed monkey holds paramount importance for its conservation. Our study represented a comprehensive investigation into the population distribution of the Sichuan snub-nosed monkey by integrating data acquired from field surveys, protected areas, and historical records and using Geographic Information Systems (GIS) to explore changes in distribution across various time periods, including the historical (the Mid-to-Late Pleistocene), recent (1980-2000), and current (2001-2023)...
April 2024: Ecology and Evolution
https://read.qxmd.com/read/38633402/cooperative-conformational-transitions-underpin-the-activation-heat-capacity-in-the-temperature-dependence-of-enzyme-catalysis
#32
JOURNAL ARTICLE
Emma J Walker, Carlin J Hamill, Rory Crean, Michael S Connolly, Annmaree K Warrender, Kirsty L Kraakman, Erica J Prentice, Alistair Steyn-Ross, Moira Steyn-Ross, Christopher R Pudney, Marc W van der Kamp, Louis A Schipper, Adrian J Mulholland, Vickery L Arcus
Many enzymes display non-Arrhenius behavior with curved Arrhenius plots in the absence of denaturation. There has been significant debate about the origin of this behavior and recently the role of the activation heat capacity (Δ C P ⧧ ) has been widely discussed. If enzyme-catalyzed reactions occur with appreciable negative values of Δ C P ⧧ (arising from narrowing of the conformational space along the reaction coordinate), then curved Arrhenius plots are a consequence. To investigate these phenomena in detail, we have collected high precision temperature-rate data over a wide temperature interval for a model glycosidase enzyme MalL, and a series of mutants that change the temperature-dependence of the enzyme-catalyzed rate...
April 5, 2024: ACS Catalysis
https://read.qxmd.com/read/38633370/hydrology-predominates-over-harvest-history-and-landscape-variation-to-control-water-quality-and-disinfection-byproduct-formation-potentials-in-forested-pacific-coast-watersheds
#33
JOURNAL ARTICLE
Alyssa K Bourgeois, Suzanne E Tank, William C Floyd, Monica B Emelko, Fariba Amiri
Despite the global importance of forested watersheds as sources of drinking water, few studies have examined the effects of forestry on drinking water treatability. Relatively little is known about how the interaction between landscape variation and flow impacts source water quality and what this interaction means for drinking water treatability. To address this knowledge gap, we examined variability in sediments, dissolved organic matter, and disinfection byproduct formation potentials (DBP-FPs) across a range of flow conditions in four small watersheds with contrasting forest harvest histories and soil characteristics on Vancouver Island...
April 12, 2024: ACS ES&T water
https://read.qxmd.com/read/38633303/a-deep-dive-into-hyperbaric-environments-and-intraocular-pressure-a-systematic-review
#34
Paul Connor Lentz, Sheng Yang Lim, Bjorn Kaijun Betzler, Darby D Miller, Syril K Dorairaj, Bryan Chin Hou Ang
PURPOSE: SCUBA diving exposes participants to a unique hyperbaric environment, but few studies have examined the effects of such an environment on intraocular pressure (IOP) and glaucoma. This systematic review aims to consolidate recent literature findings regarding the impact of increased atmospheric pressure on IOP and glaucoma. METHODS: Three online databases were searched to identify publications encompassing the subjects of diving or increased atmospheric pressure in conjunction with IOP or glaucoma...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38633234/examination-of-medical-student-and-physician-attitudes-towards-suicide-reveals-need-for-required-training
#35
REVIEW
Paulyna Schulz, Isain Zapata, Teodor Huzij
The attitudes of healthcare providers towards suicidal patients are known to influence their motivation to treat patients during a suicidal crisis. Patients who attempted suicide are more likely to have recently visited a primary care provider who is not necessarily sufficiently trained in managing a suicidal patient rather than a mental health provider who is trained to do so. For those reasons, documenting medical students and physicians' attitudes towards suicide can help in the development of effective intervention training to prepare them to manage these types of patients...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38633081/tissue-mimicking-materials-and-finger-phantom-design-for-pulse-oximetry
#36
JOURNAL ARTICLE
Andres J Rodriguez, Sandhya Vasudevan, Masoud Farahmand, Sandy Weininger, William C Vogt, Christopher G Scully, Jessica Ramella-Roman, T Joshua Pfefer
Pulse oximetry represents a ubiquitous clinical application of optics in modern medicine. Recent studies have raised concerns regarding the potential impact of confounders, such as variable skin pigmentation and perfusion, on blood oxygen saturation measurement accuracy in pulse oximeters. Tissue-mimicking phantom testing offers a low-cost, well-controlled solution for characterizing device performance and studying potential error sources, which may thus reduce the need for costly in vivo trials. The purpose of this study was to develop realistic phantom-based test methods for pulse oximetry...
April 1, 2024: Biomedical Optics Express
https://read.qxmd.com/read/38633029/zoo-professionals-and-volunteers-in-the-u-s-experiences-and-prevalence-of-burnout-mental-health-and-animal-loss
#37
JOURNAL ARTICLE
Shelby E McDonald, Lori R Kogan, Nichole L Nageotte, Jennifer Currin-McCulloch, Rachel Dickler-Mann
INTRODUCTION: Burnout and mental health among animal care and health professionals (ACHPs) has received increasing attention in recent years. Despite rapid growth of research in this area, the wellbeing of individuals who work and/or volunteer in zoo settings has received minimal attention. METHOD: An anonymous online survey was created to evaluate zoo staff and volunteers' experiences of animal-related loss, rates of professional fulfillment and burnout, mental health, perceived organizational support, and resilience...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38632925/developing-a-selection-framework-for-zinc-ion-based-biomaterial-design-guided-by-the-biosafety-assessment-of-zif-8-and-zno
#38
JOURNAL ARTICLE
Yilin Mao, Liang Wang, Zhengyi Xu, Wenjia Xie, Yuting Wang, Wei Qiao, Zhou Zhu, Jian Wang
In recent years, nanomaterials have gained widespread use in the biomedical field, with ZIF-8 and ZnO emerging as promising candidates due to their remarkable performance in osteogenesis, angiogenesis, and antimicrobial therapy. However, before advancing these nanomaterials for clinical applications, it is imperative to evaluate their biocompatibility. In particular, comparing nanomaterials with similar biomedical functions is crucial for identifying the most suitable nanomaterials for further development and market entry...
April 17, 2024: ACS Biomaterials Science & Engineering
https://read.qxmd.com/read/38632845/high-fat-diet-wheat-gliadin-interaction-and-its-implication-for-obesity-and-celiac-disease-onset-in-vivo-studies
#39
REVIEW
Yuri Haneishi, Lucia Treppiccione, Francesco Maurano, Diomira Luongo, Junki Miyamoto, Mauro Rossi
The intestinal immune system plays a crucial role in obesity and insulin resistance. An altered intestinal immunity is associated with changes to the gut microbiota, barrier function, and tolerance to luminal antigens. Lipid metabolism and its unbalance can also contribute to acute and chronic inflammation in different conditions. In celiac disease (CD), the serum phospholipid profile in infants who developed CD is dramatically different when compared to that of infants at risk of CD not developing the disease...
April 17, 2024: Molecular Nutrition & Food Research
https://read.qxmd.com/read/38632842/evaluation-of-organic-hydride-acid-pairs-as-a-type-of-thermodynamic-potential-regulated-multisite-proton-coupled-electron-transfer-reagents
#40
JOURNAL ARTICLE
Guang-Bin Shen, Guang-Ze Luo, Bao-Chen Qian, Xiao-Qing Zhu
Organic hydride/acid pairs have been reported as multisite proton-coupled electron transfer (MS-PCET) reagents in reductive MS-PCET reactions recently. Since the key step for an organic hydride/acid pair acting as an MS-PCET reagent is a chemical process of the organic hydride/acid pair releasing a formal hydrogen atom, the bond dissociation free energy of the organic hydride/acid pair releasing a formal hydrogen atom is a valuable thermodynamic parameter for objectively evaluating the thermodynamic potential for an organic hydride/acid pair to act as an MS-PCET reagent...
April 17, 2024: Journal of Organic Chemistry
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