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https://www.readbyqxmd.com/read/28728401/research-trends-in-outdoor-pig-production
#1
Hyun-Suk Park, Sang Hyon Oh
Since the industrialization of swine production in the late 1900s, swine farms in the United States, as well as in Europe, have largely become consolidated. Pig farms became larger in size but fewer in number, with 91% of market pigs being produced by large operations with 5,000 or more pigs on-site in the US, and only 3% of the total utilized agricultural land representing organic farming. Such change in the market made it difficult for small farmers to stay competitive, forcing them to find alternative ways to reduce the cost of production and increase profit using the outdoor production system...
July 17, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28728347/pros-and-cons-of-health-transformation-program-in-iran-evidence-from-financial-outcomes-at-household-level
#2
Enayatollah Homaie Rad, Vahid Yazdi-Feyzabadi, Shahrokh Yousefzadeh-Chabok, Abolhasan Afkar, Ahmad Naghibzadeh Tahami
Purpose: Health transformation program (HTP) is one of the recent reforms in health system of Iran implemented in early 2014. Improving the equity of payments and reducing out of pocket (OOP) and catastrophic health expenditures (CHE) were some of the program's important goals. In this study these goals were evaluated using a before-after analysis. Methods: Household income and expenditures data of Guilan province were gathered for years 2013-2015. OOP payments for outpatient, inpatient and drug services were calculated and the results were compared using propensity score matching technique after adjustment of confounding variables...
July 18, 2017: Epidemiology and Health
https://www.readbyqxmd.com/read/28728314/local-recurrence-and-its-risk-factor-after-incomplete-resection-of-colorectal-advanced-adenomas-a-single-center-retrospective-study
#3
Dae Myung Oh, Jae Kwang Lee, Hyunsoo Kim, Chang Keun Park, Jae Kwon Jung, Dae Jin Kim, Yun Jin Chung, Tae Hoon Kim, Myung Il Park, Jong Pil Park
Background/Aims: Colonoscopy can detect precancerous lesions, which can subsequently be removed and reduce incidences of and mortality from colorectal cancer (CRC). However, recently published data have highlighted a significant rate of CRC in patients who previously underwent colonoscopy. Among many reasons, incomplete resection has been considered as a significant contributor. However, to date, there have only been a few studies regarding incompletely resected polyps, especially advanced colorectal adenoma (ACA)...
July 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28728290/-advances-in-research-of-divergence-insufficiency
#4
Y P Li, W Zhang
Divergence insufficiency is acquired esotropia at distance fixation with symptomatic uncrossed diplopia but fusion at near. It can be divided into two forms: primary isolated form and secondary form associated with neurologic abnormalities, also called divergence palsy. The clinical features of divergence insufficiency include small esotropia only at distance but orthotropia or small esophoria at near, comitant deviation at lateral gaze, reduced divergence fusion, full abduction and normal saccadic velocities in abduction...
July 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28727919/comprehensive-multiphase-cmp-nmr-monitoring-of-the-structural-changes-and-molecular-flux-within-a-growing-seed
#5
Blythe Fortier-McGill, Rudraksha Dutta Majumdar, Leayen Lam, Ronald Soong, Yalda Liaghati Mobarhan, Andre Sutrisno, Ries de Visser, Myrna J Simpson, Heather Wheeler, Malcolm Campbell, Antonie Gorissen, Andre J Simpson
A relatively recent technique termed Comprehensive Multiphase (CMP) NMR spectroscopy was used to study the growth and associated metabolomic changes of 13C-labeled wheat seeds and germinated seedlings. CMP-NMR enables the study of all phases in intact samples: liquid, gel-like, semi-solid and solid, by combining all required electronics into a single NMR probe and can be used for investigating biological processes such as seed germination. All components, from the most liquid like (i.e. dissolved metabolites) to the most rigid or solid like (seed coat) were monitored in-situ over 4 days...
July 20, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28727843/atomistic-modeling-of-alternating-access-of-a-mitochondrial-adp-atp-membrane-transporter-with-molecular-simulations
#6
Koichi Tamura, Shigehiko Hayashi
The mitochondrial ADP/ATP carrier (AAC) is a membrane transporter that exchanges a cytosolic ADP for a matrix ATP. Atomic structures in an outward-facing (OF) form which binds an ADP from the intermembrane space have been solved by X-ray crystallography, and revealed their unique pseudo three-fold symmetry fold which is qualitatively different from pseudo two-fold symmetry of most transporters of which atomic structures have been solved. However, any atomic-level information on an inward-facing (IF) form, which binds an ATP from the matrix side and is fixed by binding of an inhibitor, bongkrekic acid (BA), is not available, and thus its alternating access mechanism for the transport process is unknown...
2017: PloS One
https://www.readbyqxmd.com/read/28727813/label-free-three-dimensional-imaging-of-caenorhabditis-elegans-with-visible-optical-coherence-microscopy
#7
Séverine Coquoz, Paul J Marchand, Arno Bouwens, Laurent Mouchiroud, Vincenzo Sorrentino, Daniel Szlag, Johan Auwerx, Theo Lasser
Fast, label-free, high-resolution, three-dimensional imaging platforms are crucial for high-throughput in vivo time-lapse studies of the anatomy of Caenorhabditis elegans, one of the most commonly used model organisms in biomedical research. Despite the needs, methods combining all these characteristics have been lacking. Here, we present label-free imaging of live Caenorhabditis elegans with three-dimensional sub-micrometer resolution using visible optical coherence microscopy (visOCM). visOCM is a versatile optical imaging method which we introduced recently for tomography of cell cultures and tissue samples...
2017: PloS One
https://www.readbyqxmd.com/read/28727760/detection-of-titin-fragments-in-urine-in-response-to-exercise-induced-muscle-damage
#8
Kazue Kanda, Jun Sakuma, Takayuki Akimoto, Yasuo Kawakami, Katsuhiko Suzuki
Many studies have attempted to determine the associations between blood biomarkers and exercise-induced muscle damage. However, poor correlations between the changes in biomarker levels and the magnitude of muscle symptoms have been reported. Recent advances in proteomic tools offer a strategy for the comprehensive analysis of protein expression, which can be used to identify biomarkers. Here, we used a proteomic analysis to identify urinary proteins that appear in response to a calf-raise exercise, including repetitive eccentric muscle contractions, and found that a titin (also known as connectin) N-terminal fragment molecule appears in the urine after eccentric exercise...
2017: PloS One
https://www.readbyqxmd.com/read/28727515/brave-new-worlds-the-expanding-universe-of-lyme-disease
#9
Brandee L Stone, Yvonne Tourand, Catherine A Brissette
Projections around the globe suggest an increase in tick-vectored disease incidence and distribution, and the potential for emergence of novel tick-borne pathogens. Lyme disease is the most common reported tick-borne illness in the Unites States and is prevalent throughout much of central Europe. In recent years, the worldwide burden of Lyme disease has increased and extended into regions and countries where the disease was not previously reported. In this review, we discuss the trends for increasing Lyme disease, and examine the factors driving Lyme disease expansion, including the effect of climate change on the spread of vector Ixodid ticks and reservoir hosts; and the impacts of increased awareness on disease reporting and diagnosis...
July 20, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28727447/a-systematic-comparison-between-half-and-full-dielectric-barrier-discharges-based-on-the-ltp-and-dbdi-configurations
#10
Felix David Klute, Sebastian Brandt, Pascal Vogel, Beatrix Biskup, Charlotte Reininger, Vlasta Horvatic, Cedomil Vadla, Paul B Farnsworth, Joachim Franzke
Dielectric barrier discharge (DBD)-based analytical applications have experienced rapid development in recent years. DBD designs and parameters and the application they are used for can vary considerably. This leads to a diverse field with many apparently unique systems that are all based on the same physical principle. The most significant changes among DBDs used for chemical analysis are in how the discharge electrodes are separated from the ignited discharge gas. While the official definition of a DBD states that at least one electrode has to be covered by a dielectric to be considered a DBD, configurations with both electrodes covered by dielectric layers can also be realized...
July 20, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28727250/lack-of-adjustment-for-confounding-could-lead-to-misleading-conclusions
#11
EDITORIAL
S Christakoudi, M P Hernandez-Fuentes
In a recent issue Asare et al. (1) assess the utility of a previously identified signature of tolerance, based on the expression of two B-cell receptor genes (IGKV1D-13 and IGKV4-1). The authors set to determine the prevalence of "tolerance" predictions in treated stable kidney transplant recipients (KTRs) and "tolerance" frequency in patients with different immunosuppressant (IS) regimens. They illustrate (Figure 6), very successfully, that changes in the signature are compatible with known alterations of the B-cell compartment elicited by IS drugs...
July 20, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28727210/thermal-affinity-as-the-dominant-factor-changing-mediterranean-fish-abundances
#12
Or Givan, Dor Edelist, Oren Sonin, Jonathan Belmaker
Recent decades have seen profound changes in species abundance and community composition. In the marine environment, the major anthropogenic drivers of change comprise exploitation, invasion by non-indigenous species, and climate change. However, the magnitude of these stressors has been widely debated and we lack empirical estimates of their relative importance. In this study, we focused on Eastern Mediterranean, a region exposed to an invasion of species of Red Sea origin, extreme climate change, and high fishing pressure...
July 20, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28727021/physiology-and-endocrinology-symposium-the-effects-of-poor-maternal-nutrition-during-gestation-on-offspring-postnatal-growth-and-metabolism
#13
M L Hoffman, S A Reed, S M Pillai, A K Jones, K K McFadden, S A Zinn, K E Govoni
Poor maternal nutrition during gestation has been linked to poor growth and development, metabolic dysfunction, impaired health, and reduced productivity of offspring in many species. Poor maternal nutrition can be defined as an excess or restriction of overall nutrients or specific macro- or micronutrients in the diet of the mother during gestation. Interestingly, there are several reports that both restricted- and over-feeding during gestation negatively affect offspring postnatal growth with reduced muscle and bone deposition, increased adipose accumulation, and metabolic dysregulation through reduced leptin and insulin sensitivity...
May 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28726764/fluorination-of-naturally-occurring-n%C3%A2-benzyladenosine-remarkably-increased-its-antiviral-activity-and-selectivity
#14
Vladimir E Oslovsky, Mikhail S Drenichev, Liang Sun, Nikolay N Kurochkin, Vladislav E Kunetsky, Carmen Mirabelli, Johan Neyts, Pieter Leyssen, Sergey N Mikhailov
Recently, we demonstrated that the natural cytokinin nucleosides N⁶-isopentenyladenosine (iPR) and N⁶-benzyladenosine (BAPR) exert a potent and selective antiviral effect on the replication of human enterovirus 71. In order to further characterize the antiviral profile of this class of compounds, we generated a series of fluorinated derivatives of BAPR and evaluated their activity on the replication of human enterovirus 71 in a cytopathic effect (CPE) reduction assay. The monofluorination of the BAPR-phenyl group changed the selectivity index (SI) slightly because of the concomitant high cell toxicity...
July 20, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28726752/health-impacts-of-climate-change-induced-subzero-temperature-fires
#15
Maria-Monika Metallinou, Torgrim Log
General fire risk and the special risk related to cold climate cellulosic drying processes are outlined. Four recent subzero temperatures fires are studied with respect to health impacts: a wooden village fire, a single wood structure fire, a wildland urban interface (WUI) fire and a huge wildland fire. The health impacts range from stress related to loss of jobs, psychological effects of lost possessions, exposure to smoke and heat as well as immediate, or delayed, loss of lives. These four fires resulted in 32 fatalities, 385 persons hospitalized for shorter or longer periods, 104 structures lost and 1015 km² of wildland burned north of, and just south of, the Arctic Circle...
July 20, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28726744/future-protein-supply-and-demand-strategies-and-factors-influencing-a-sustainable-equilibrium
#16
REVIEW
Maeve Henchion, Maria Hayes, Anne Maria Mullen, Mark Fenelon, Brijesh Tiwari
A growing global population, combined with factors such as changing socio-demographics, will place increased pressure on the world's resources to provide not only more but also different types of food. Increased demand for animal-based protein in particular is expected to have a negative environmental impact, generating greenhouse gas emissions, requiring more water and more land. Addressing this "perfect storm" will necessitate more sustainable production of existing sources of protein as well as alternative sources for direct human consumption...
July 20, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28726716/new-insights-into-the-role-of-matrix-metalloproteinases-in-preeclampsia
#17
REVIEW
Salvador Espino Y Sosa, Arturo Flores-Pliego, Aurora Espejel-Nuñez, Diana Medina-Bastidas, Felipe Vadillo-Ortega, Veronica Zaga-Clavellina, Guadalupe Estrada-Gutierrez
Preeclampsia is a severe pregnancy complication globally, characterized by poor placentation triggering vascular dysfunction. Matrix metalloproteinases (MMPs) exhibit proteolytic activity implicated in the efficiency of trophoblast invasion to the uterine wall, and a dysregulation of these enzymes has been linked to preeclampsia. A decrease in MMP-2 and MMP-9 interferes with the normal remodeling of spiral arteries at early pregnancy stages, leading to the initial pathophysiological changes observed in preeclampsia...
July 20, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28726685/enhanced-thermoelectric-performance-of-bi-sub-2-sub-te-sub-3-sub-by-uniform-dispersion-of-single-wall-carbon-nanotubes
#18
Kaleem Ahmad, Chunlei Wan
The advancement in nanostructured powder processing has attracted recently great interest as a cost effective and scalable strategy for high performance thermoelectric bulks. However, the level of technical breakthrough as realized in quantum dot supperlattice/wire has not yet demonstrated in these materials. Here, we report first ever study on the uniform dispersion of single wall carbon nanotubes (SWCNTs) in nanostructured Bi2Te3 bulk and their effect on thermoelectric parameters above room temperature. The Bi<sub>2</sub>Te<sub>3</sub> based SWCNTs composites were prepared through controlled powder processing and their thermoelectric properties were finely tuned at nanoscale by regulating various (0...
July 20, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28726600/age-and-sex-associated-differences-in-phenotypic-and-functional-characteristics-of-peripheral-blood-lymphocytes-in-chimpanzees-pan-troglodytes
#19
Pramod Nehete, Elizabeth Magden, Bharti Nehete, Lawrence Williams, Christian Abee, K Sastry
Chimpanzees are the closest phylogenetic relatives to humans, sharing more than 98% genetic sequence identity. Thesegenetic similarities prompted the belief that chimpanzees can serve as an ideal model for human disease conditions andvaccine development. However, in light of the recent NIH decision to phase out biomedical research in chimpanzees and retire NIH-supported chimpanzees, data from the present study will continue to provide value for the care of aged and sick chimpanzees located in zoos, sanctuaries, and primate centers...
July 19, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28726589/proteomic-study-of-sumoylation-during-solanum-tuberosum-phytophthora-infestans-in-compatible-interactions
#20
Bertrand Colignon, Marc Dieu, Catherine Demazy, Edouard Delaive, Yordan Muhovski, Martine Raes, Sergio Mauro
Invasive plant pathogens have developed the ability to modify the metabolism of their host, promoting metabolic processes which facilitate the growth of the pathogen; at the general expense of the host. The particular enzymatic process SUMOylation which performs post-translational modification of target proteins, leading to changes in many aspects of protein activity and hence metabolism has been demonstrated to be active in many eukaryotic organisms, both animals and plants. Here we provide experimental evidence which indicates that in leaves of Solanum tuberosum which have been infected by Phytophthora infestans, the SUMO pathway enzymes of the host are partially under transcriptional control exerted by the oomycete...
July 20, 2017: Molecular Plant-microbe Interactions: MPMI
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