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https://www.readbyqxmd.com/read/29455170/comparison-and-validation-of-screening-tools-for-substance-use-in-pregnancy-a-cross-sectional-study-conducted-in-maryland-prenatal-clinics
#1
Victoria H Coleman-Cowger, Emmanuel A Oga, Erica N Peters, Kathleen Trocin, Bartosz Koszowski, Katrina Mark
INTRODUCTION: Prescription-drug use in the USA has increased by more than 60% in the last three decades. Prevalence of prescription-drug use among pregnant women is currently estimated around 50%. Prevalence of illicit drug use in the USA is 14.6% among pregnant adolescents, 8.6% among pregnant young adults and 3.2% among pregnant adults. The first step in identifying problematic drug use during pregnancy is screening; however, no specific substance-use screener has been universally recommended for use with pregnant women to identify illicit or prescription-drug use...
February 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29453006/illicit-and-prescription-drug-misuse-as-reported-to-the-maine-diversion-alert-program
#2
Brian J Piper, Michael J Suarez, John P Piserchio, Dipam T Shah, Olapeju M Simoyan, Kenneth L McCall, Clare E Desrosiers, Stephanie D Nichols
BACKGROUND: The opioid epidemic is rapidly evolving and new tools are needed to combat drug abuse. The Maine Diversion Alert Program (DAP) is an informational resource that facilitates communication about drug arrests between the criminal justice and healthcare fields. The objectives of this report were to: (1) describe the illegal and prescription pharmaceuticals reported to the DAP; (2) determine if the drugs implicated in arrests changed from the first to latter half of 2016; (3) identify the demographic and other characteristics of arrestees; and (4) outline the strengths and limitations of the DAP for other areas considering implementing similar programs...
February 6, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29452560/health-care-efficiencies-consolidation-and-alternative-models-vs-health-care-and-antitrust-regulation-irreconcilable-differences
#3
Michael W King
Despite the U.S. substantially outspending peer high income nations with almost 18% of GDP dedicated to health care, on any number of statistical measurements from life expectancy to birth rates to chronic disease, 1 the U.S. achieves inferior health outcomes. In short, Americans receive a very disappointing return on investment on their health care dollars, causing economic and social strain. 2 Accordingly, the debates rage on: what is the top driver of health care spending? Among the culprits: poor communication and coordination among disparate providers, paperwork required by payors and regulations, well-intentioned physicians overprescribing treatments, drugs and devices, outright fraud and abuse, and medical malpractice litigation...
November 2017: American Journal of Law & Medicine
https://www.readbyqxmd.com/read/29437536/opioid-stewardship-in-otolaryngology-state-of-the-art-review
#4
John D Cramer, Brad Wisler, And Christopher J Gouveia
Objective The United States is facing an epidemic of opioid addiction. Deaths from opioid overdose have quadrupled in the past 15 years and now surpass annual deaths during the height of the human immunodeficiency virus epidemic. There is a link between opioid prescriptions after surgery, opioid misuse, opioid diversion, and use of other drugs of abuse. As surgeons, otolaryngologists contribute to this crisis. Our objective is to outline the risk of abuse from opioids in the management of acute postoperative pain in otolaryngology-head and neck surgery (OHNS) and strategies to avoid misuse...
February 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29436015/medical-prescriptions-falsified-by-the-patients-a-twelve-year-national-monitoring-to-assess-prescription-drug-diversion
#5
Emilie Jouanjus, Grégory Guernec, Maryse Lapeyre-Mestre
Diversion of prescription drugs is difficult to assess in quality and quantity. This study aimed to characterize diversion of prescription drugs in France through a comparative analysis of falsified prescriptions collected during three periods from 2001 to 2012. The data recorded in a national program which records all falsified prescriptions presented to community pharmacies were studied. Included data regarded: subjects, prescription forms and drugs. Description of the dataset in 3 periods (2001-2004, 2005-2008, and 2009-2012) was completed with clustering analyses to characterize profiles of prescriptions and subjects associated with the most reported drugs...
February 13, 2018: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/29414488/examining-social-supply-among-nonmedical-prescription-stimulant-users-in-the-san-francisco-bay-area
#6
Fiona Murphy, Sheigla Murphy, Paloma Sales, Nicholas Lau
In the US, prescription stimulants are prescribed for a variety of conditions including attention deficit hyperactivity disorder (ADHD) and narcolepsy. Over the last two decades, dramatic increases in stimulant prescriptions have led to greater availability and increased risk for diversion and nonmedical use. Our own and other investigators' findings indicate that many drug "suppliers" do not fit into the traditional image of drug "dealers." These suppliers typically do not identify themselves as "dealers," but instead understand their drug distribution as sharing with people they know...
January 30, 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29403573/comparing-the-medicaid-retrospective-drug-utilization-review-program-cost-savings-methods-used-by-state-agencies
#7
REVIEW
Sergio I Prada
Background: The Medicaid Drug Utilization Review (DUR) program is a 2-phase process conducted by Medicaid state agencies. The first phase is a prospective DUR and involves electronically monitoring prescription drug claims to identify prescription-related problems, such as therapeutic duplication, contraindications, incorrect dosage, or duration of treatment. The second phase is a retrospective DUR and involves ongoing and periodic examinations of claims data to identify patterns of fraud, abuse, underutilization, drug-drug interaction, or medically unnecessary care, implementing corrective actions when needed...
December 2017: American Health & Drug Benefits
https://www.readbyqxmd.com/read/29389167/adolescent-d-amphetamine-exposure-enhances-the-acquisition-of-cocaine-self-administration-in-male-and-female-rats
#8
Ryan T Lacy, Hannah K Schorsch, Bridget P Austin
Diagnosis and treatment of attention-deficit/hyperactivity disorder (ADHD) has risen drastically over the past 20 years in the United States and abroad. Amphetamine-based prescription stimulants are the most prescribed treatment for ADHD and the diversion of these drugs has also increased. Reports indicate 61% of individuals with an ADHD medication prescription have sold or shared their medication. Exposure to prescription stimulants, especially for those without an ADHD diagnosis, may increase susceptibility to drugs of abuse...
February 2018: Experimental and Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29387512/mycobacteremia-from-crushed-hydromorphone-tablet-injection
#9
Joseph M Banno, Katherine Shield, Krunal Patel, Anupam A Sule
Mycobacterium abscessus is a fast growing, non-tubercular mycobacterium (NTM) found in water. NTM bacteremia is usually seen in immunocompromised patients who have intravascular catheters. Mycobacterium abscessus bacteremia is often caused by exposure to contaminated water supply in hemodialysis units. A 28-year-old female with poorly controlled diabetes mellitus, end stage renal disease (on hemodialysis via Ash catheter), and recurrent deep vein thrombosis presented to the hospital with proximal right leg deep vein thrombosis...
November 27, 2017: Curēus
https://www.readbyqxmd.com/read/29387325/stimulant-use-in-medical-students-and-residents-requires-more-careful-attention
#10
Golnaz Fallah, Sussan Moudi, Angela Hamidia, Ali Bijani
Background: Stimulant pharmaceuticals are abused among academic students to elevate mood, improve studying, intellectual capacity, memory and concentration, and increase wakefulness. This study was designed to evaluate the current situation of stimulant use among medical students and residents of Babol University of Medical Sciences. Methods: This cross-sectional study was conducted among 560 medical students and clinical residents of Babol University of Medical Sciences during the academic year 2014-2015...
2018: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/29385766/benzodiazepines-ii-waking-up-on-sedatives-providing-optimal-care-when-inheriting-benzodiazepine-prescriptions-in-transfer-patients
#11
REVIEW
Jeffrey Guina, Brian Merrill
This review discusses risks, benefits, and alternatives in patients already taking benzodiazepines when care transfers to a new clinician. Prescribers have the decision-sometimes mutually agreed-upon and sometimes unilateral-to continue, discontinue, or change treatment. This decision should be made based on evidence-based indications (conditions and timeframes), comorbidities, potential drug-drug interactions, and evidence of adverse effects, misuse, abuse, dependence, or diversion. We discuss management tools involved in continuation (e...
January 30, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29385414/newly-emerging-drugs-of-abuse-and-their-detection-methods-an-aclps-critical-review
#12
Li Liu, Sarah E Wheeler, Raman Venkataramanan, Jacqueline A Rymer, Anthony F Pizon, Michael J Lynch, Kenichi Tamama
Objectives: Illicit drug abuse has reached an epidemic level in the United States. Drug overdose has become the leading cause of injury-related deaths since 2008 due to the recent surge of opioid overdose by heroin, controlled prescription drugs, and nonmethadone synthetic opioids. Synthetic designer drugs such as synthetic cathinones ("bath salts") and synthetic cannabinoids ("Spice" and "K2") continue to emerge and attract recreational users. Methods: The emergence of new drugs of abuse poses a steep challenge for clinical toxicology laboratories...
January 29, 2018: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29381219/spatial-epidemiology-of-alcohol-and-drug-related-health-problems-among-northern-plains-american-indians-nebraska-and-south-dakota-2007-to-2012
#13
William R Ponicki, Jeffrey A Henderson, Andrew Gaidus, Paul J Gruenewald, Juliet P Lee, Roland S Moore, Sharice Davids, Nick Tilsen
BACKGROUND: Despite high abstinence rates, American Indians experience elevated rates of many alcohol and other drug problems. American Indians also predominantly reside in poor and rural areas, which may explain some observed health disparities. We investigated whether geographic areas including reservations or large American Indian populations exhibited greater incidence of alcohol- and drug-related hospitalizations. METHODS: We obtained inpatient hospitalization records for 2 Northern Plain states (Nebraska and South Dakota) for the years 2007 to 2012...
January 30, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29366528/corrigendum-to-prescription-drug-monitoring-program-utilization-among-15-us-opioid-treatment-programs-j-subst-abus-treat-85-2018-17-20
#14
Harlan Matusow, Andrew Rosenblum, Mark Parrino
No abstract text is available yet for this article.
January 20, 2018: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/29360020/the-oral-health-of-preschool-children-of-refugee-and-immigrant-families-in-manitoba
#15
Mahyar Etminan, M Reza Nouri, Mohit Sodhi, Bruce C Carleton
OBJECTIVE: Recently, there has been great interest in the use, abuse and over-prescribing of opioid analgesics for children. However, there is a paucity of evidence on patterns of prescribing of both narcotic and non-narcotic analgesics for children by dentists. METHODS: We used a population-wide prescription drug database (PharmaNet) in British Columbia, Canada, to examine prescribing and dispensing of analgesics surrounding dental procedures. We examined all drugs prescribed for children by dentists between 1997 and 2013, as we had access to data on drug doses and days of medication supply...
August 2017: Journal—Canadian Dental Association, Journal de L'Association Dentaire Canadienne
https://www.readbyqxmd.com/read/29327358/opioid-medication-use-in-patients-with-gastrointestinal-diagnoses-vs-unexplained-gastrointestinal-symptoms-in-the-us-veterans-health-administration
#16
G S Sayuk, N Kanuri, C P Gyawali, B M Gott, B D Nix, R A Rosenheck
BACKGROUND: While opioid prescriptions have increased alarmingly in the United States (US), their use for unexplained chronic gastrointestinal (GI) pain (eg, irritable bowel syndrome) carries an especially high risk for adverse effects and questionable benefit. AIM: To compare opioid use among US veterans with structural GI diagnoses (SGID) and those with unexplained GI symptoms or functional GI diagnoses (FGID), a group for whom opioids have no accepted role. METHODS: Veterans Health Administration (VHA) administrative data from fiscal year 2012 were used to identify veterans with diagnostic codes recorded for SGID and FGID...
January 12, 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29323819/the-use-of-a-statewide-prescription-drug-monitoring-program-by-emergency-department-physicians
#17
Jennifer L Hernandez-Meier, Rachel Muscott, Amy Zosel
BACKGROUND: Little is known about how emergency physicians have used Wisconsin's Prescription Drug Monitoring Program (PDMP). OBJECTIVE: To characterize emergency physician knowledge and utilization of the program and how it modifies practice. METHODS: Online survey data were collected 1 year after program implementation. Descriptive statistics were generated and qualitative responses were grouped by content. RESULTS: Of the 63 respondents, 64...
June 2017: WMJ: Official Publication of the State Medical Society of Wisconsin
https://www.readbyqxmd.com/read/29320313/acute-radiologic-manifestations-of-america-s-opioid-epidemic
#18
David D B Bates, Katherine Gallagher, HeiShun Yu, Jennifer Uyeda, Akira M Murakami, Bindu N Setty, Stephan W Anderson, Mariza O Clement
The United States is in the midst of an opioid use epidemic, which has severe medical, social, and economic consequences. Addictions to and abuse of prescription and illicit opioids are increasing, and emergency department radiologists are increasingly being faced with the task of examining patients who present with opioid-related complications. These complications may be the result of direct drug toxicity or nonsterile injection of the drugs. Neurologic, musculoskeletal, cardiopulmonary, genitourinary, and gastrointestinal complications may be evident at diagnostic imaging in emergent settings...
January 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29308590/laboratory-based-testing-to-evaluate-abuse-deterrent-formulations-and-satisfy-the-food-and-drug-administration-s-recommendation-for-category-1-testing
#19
Christopher Altomare, Eric R Kinzler, August R Buchhalter, Edward J Cone, Anthony Costantino
The US Food and Drug Administration (FDA) considers the development of abuse-deterrent formulations of solid oral dosage forms a public health priority and has outlined a series of premarket studies that should be performed prior to submitting an application to the Agency. Category 1 studies are performed to characterize whether the abuse-deterrent properties of a new formulation can be easily defeated. Study protocols are designed to evaluate common abuse patterns of prescription medications as well as more advanced methods that have been reported on drug abuse websites and forums...
November 2017: Journal of Opioid Management
https://www.readbyqxmd.com/read/29308589/abuse-of-reformulated-oxycontin-updated-findings-from-a-sentinel-surveillance-sample-of-individuals-assessed-for-substance-use-disorder
#20
Theresa A Cassidy, Eileen Thorley, Ryan A Black, Angela DeVeaugh-Geiss, Stephen F Butler, Paul Coplan
OBJECTIVE: To examine abuse prevalence for OxyContin and comparator opioids over a 6-year period prior to and following market entry of reformulated OxyContin and assess consistency in abuse across treatment settings and geographic regions. DESIGN: An observational study examining longitudinal changes using cross-sectional data from treatment centers for substance use disorder. SETTING: A total of 874 facilities in 39 states in the United States within the National Addictions Vigilance Intervention and Prevention Program (NAVIPPRO®) surveillance system...
November 2017: Journal of Opioid Management
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