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JOURNAL ARTICLE
Vineet Kumar, Rounak Kalwani, Ameya Bindu, Saumya Mathews, Mayur Mantri, Dushyant Jaiswal, Vinay Kant Shankhdhar
Pharyngolaryngoesophageal (PLO) reconstruction is a complex and technically demanding procedure. The reconstructive surgeon's concerns include avoiding fistula and stricture formation, as well as restoring normal speech and swallowing. A retrospective observational study with circumferential pharyngo-laryngo-oesophagal defects with aims and objectives of evaluation and comparison of the long-term functional outcomes like speech and swallowing along with the complications of fistula and stricture in two groups of JFF and FC flaps from the data is collected from electronic medical records of Tata Memorial Hospital, Mumbai, from January 2011 to May 2020...
September 2023: Indian Journal of Surgical Oncology
#22
REVIEW
Faten Sid Idris, Humna Anis Shaikh, Ilma Vahora, Kiran Prasad Moparthi, Majdah T Al Rushaidi, MeghanaReddy Muddam, Omobolanle A Obajeun, Abdelrahman Abaza, Arturo P Jaramillo, Pousette Hamid
A significant portion of the pediatric population is affected by allergy diseases, which have become a worldwide public health concern. Could maternal diet during pregnancy or breastfeeding influence allergy outcomes in offspring? If this cause-and-effect relationship exists, it will be simpler to design prevention strategies to reduce the incidence of allergic disorders in children, reduce costs to the public health system and to parents, and improve the quality of life of allergic children and their parents...
September 2023: Curēus
#23
REVIEW
Ofelia Marioara Arvinte, Lăcrimioara Senila, Anca Becze, Sonia Amariei
After a period of intense development in the synthesis pharmaceutical industry, plants are making a comeback in the public focus as remedies or therapeutic adjuvants and in disease prevention and ensuring the wellbeing and equilibrium of the human body. Plants are being recommended more and more in alimentation, in their natural form, or as extracts, supplements or functional aliments. People, in general, are in search of new sources of nutrients and phytochemicals. As a result, scientific research turns to lesser known and used plants, among them being rowanberries, a species of fruit very rich in nutrients and underused due to their bitter astringent taste and a lack of knowledge regarding the beneficial effects of these fruit...
September 11, 2023: Plants (Basel, Switzerland)
#24
JOURNAL ARTICLE
Nadja Geuther, Djibril Mbarushimana, Felix Habarugira, Jean Damascene Buregeya, Mandy Kollatzsch, Roland Pfüller, Maurice Mugabowindekwe, Jules Ndoli, Frank P Mockenhaupt
OBJECTIVES: Extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-PE) are spreading globally. However, respective data from African communities including livestock and environmental specimens are rare. In a rural community of southern Rwanda, we assessed intestinal carriage of ESBL-PE among residents and livestock as well as presence in household specimens and examined associated factors. METHODS: Samples of humans and livestock (both rectal swabs), soil, water, vegetables and animal products were collected within 312 community households in Sovu, Southern Rwanda...
September 27, 2023: Tropical Medicine & International Health
#25
JOURNAL ARTICLE
Grégoire Prum, Anna Cadeau, Remi Mallart, Eric Verin
The aim of this study was to compare feeding modalities and the level of consciousness in patients with a severe brain injury during reeducation and rehabilitation. The clinical data of vegetative state or minimal conscious state due to severe traumatic brain injury hospitalized in a coma arousal unit were collected from 2012 to 2019. Feeding modalities were evaluated clinically and with functional endoscopy evaluation of swallowing or video fluoroscopy and functional oral intake scale. Evolution of consciousness was evaluated using Wessex Head Injury Matrix scale (WHIM)...
August 25, 2023: Medicine (Baltimore)
#26
JOURNAL ARTICLE
Alexandra Maștaleru, Irina Mihaela Abdulan, Andra Oancea, Alexandru Dan Costache, Raul-Alexandru Jigoranu, Mădălina Ioana Zota, Mihai Roca, Ileana-Katerina Ioniuc, Cristina Rusu, Laura Mihaela Trandafir, Elena Țarcă, Maria Magdalena Leon, Carmen Marinela Cumpăt, Florin Mitu
(1) Background: Familial hypercholesterolemia (FH) is a genetic disease that has autosomal dominant inheritance, being characterized by increased levels of low-density lipoproteins (LDLs) due to a decreased clearance of the circulant LDLs. Alimentation is a key factor in patients with FH. Implementing a restrictive diet may have a significant impact on their quality of life, besides the social and environmental factors. (2) Methods: We realized a prospective study that was conducted in the Cardiovascular Rehabilitation Clinic from the Clinical Rehabilitation Hospital and that included 70 patients with FH and 20 controls (adults with no comorbidities)...
August 21, 2023: Nutrients
#27
REVIEW
Frederic Karim, Adina Amin, Marie Liu, Nivetha Vishnuvardhan, Saif Amin, Raffey Shabbir, Brandon Swed, Uqba Khan
PURPOSE: This article reviews the essential clinical trials that have led to these immunotherapy approvals and explores the use of predictive biomarkers, such as PD-L1 expression and MSI status, to identify patients who are most likely to benefit from immunotherapies. METHODS: This case review series describe findings from different clinical trials and contribute to the evolving understanding of the role of CPIs in managing advanced gastroesophageal cancers and may lead to improved treatment options and patient outcomes...
August 14, 2023: Cancers
#28
JOURNAL ARTICLE
Carlos J Roldan, David I Rosenthal, Dhanalakshmi Koyyalagunta, Lei Feng, Keith Warner
Pain from radiation-therapy-induced oral mucositis during head-neck cancer treatment is aggravated by concurrent chemotherapy and commonly fails traditional treatments. To explore safe and sustainable alternatives, we investigated methylene blue oral rinse to reduce radiation-therapy-related oral mucositis pain. For this, we conducted a retrospective observational cohort study in a tertiary-care academic care cancer center including 85 patients with refractory oral mucositis pain during radiation therapy for head-neck cancer...
August 7, 2023: Cancers
#29
JOURNAL ARTICLE
Bárbara Gimenes de Castro, Bruno Mari Fredi, Rafael Dos Santos Bezerra, Queren Apuque Alcantara, Carlos Eduardo Milani Neme, Daniele Enriquetto Mascarelli, Aline Seiko Carvalho Tahyra, Douglas Dos-Santos, Camilla Rizzo Nappi, Fernanda Santos de Oliveira, Flavia Pereira Freire, Giulia Ballestero, Julia Beatriz Menuci Lima, Juliana de Andrade Bolsoni, Juliana Lourenço Gebenlian, Naira Lopes Bibo, Nathália Soares Silva, Nilton de Carvalho Santos, Victoria Simionatto Zucherato, Kamila Chagas Peronni, Daniel Guariz Pinheiro, Emmanuel Dias-Neto, Gilberto Gambero Gaspar, Valdes Roberto Bollela, Vanessa da Silva Silveira, Aparecida Maria Fontes, Nilce Maria Martinez-Rossi, Svetoslav Nanev Slavov, João Paulo Bianchi Ximenez, Fernando Barbosa, Wilson Araújo Silva
Nosocomial infections (NIs) appear in patients under medical care in the hospital. The surveillance of the bacterial communities employing high-resolution 16S rRNA profiling, known as metabarcoding, represents a reliable method to establish factors that may influence the composition of the bacterial population during NIs. The present study aimed to utilize high-resolution 16S rRNA profiling to identify high bacterial diversity by analyzing 11 inside and 10 outside environments from the General Hospital of Ribeirão Preto Medical School, Brazil...
August 11, 2023: Journal of Toxicology and Environmental Health. Part A
#30
JOURNAL ARTICLE
Maria Conticchio, Antonella Delvecchio, Valentina Ferraro, Matteo Stasi, Annachiara Casella, Rosalinda Filippo, Michele Tedeschi, Riccardo Memeo
BACKGROUND: Since its introduction 2 decades ago, robotics has been increasingly used for resection of benign and malignant liver lesions. The robotic platform seems to preserve minimally invasive approach benefits, overcoming laparoscopy limitations. Robotic right liver mobilisation represents a key step for many robotic resections from non-anatomical resections of posterosuperior segments to right hepatectomy. METHODS: We present here a standardized technique of right hepatic lobe mobilisation including technical steps and videos...
July 18, 2023: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
#31
JOURNAL ARTICLE
Giulia Gaggi, Andrea Di Credico, Federica Barbagallo, Barbara Ghinassi, Angela Di Baldassarre
Bisphenols and Perfluoroalkyls are chemical compounds widely used in industry known to be endocrine disruptors (EDs). Once ingested through contaminated aliments, they mimic the activity of endogenous hormones leading to a broad spectrum of diseases. Due to the extensive use of plastic in human life, particular attention should be paid to antenatal exposure to Bisphenols and Perfluoroalkyls since they cross the placental barrier and accumulates in developing embryo. Here we investigated the effects of Bisphenol-A (BPA), Bisphenol-S (BPS), perfluorooctane-sulfonate (PFOS) and perfluorooctanoic-acid (PFOA), alone or combined, on human-induced pluripotent stem cells (hiPSCs) that share several biological features with the stem cells of blastocysts...
July 5, 2023: Environmental Research
#32
JOURNAL ARTICLE
Mei Mei Tew, Ernieda Hatah, Maisarah Zakaria, Mohd Makmor-Bakry
INTRODUCTION: Minor ailments can be defined as medical conditions that can be self-diagnosed, resolve on their own, and be self-managed with over-the-counter (OTC) medications. Nevertheless, minor ailment management was reported to consume much of the health care resources, which may burden the health care system as it increases patient waiting times and the doctors' workload. PURPOSE: To evaluate the publics' knowledge, perceptions, and practice on the management of minor ailments in community pharmacies in Malaysia and factors that may influence it...
2023: Patient Preference and Adherence
#33
JOURNAL ARTICLE
Kirstin E Wingate, Jennifer Gerdts, Lianne Soller, Edmond S Chan
Purpose: To assess knowledge of Canadian dietitians on the topics of food allergy and food allergy prevention guidelines, including introduction of allergenic solids to infants at risk of food allergy. Methods: An online survey was distributed via email listservs targeting Canadian dietitians. Results: In total, 144 of 261 dietitians completed the survey (60.5%). Respondents recommend introduction of peanut (89.5%) and allergenic solids (91.2%) within the recommended age of 4-6 months for infants at high risk of food allergy, but only 26...
June 28, 2023: Canadian Journal of Dietetic Practice and Research
#34
JOURNAL ARTICLE
Milica Aćimović, Jovana Stanković Jeremić, Ana Miljković, Milica Rat, Biljana Lončar
Ironwort ( Sideritis montana L.), mountain germander ( Teucrium montanum L.), wall germander ( Teucrium chamaedrys L.), and horehound ( Marrubium peregrinum L.) are species widely distributed across Europe and are also found in North Africa and West Asia. Because of their wide distribution they express significant chemical diversity. For generations, these plants have been used as medical herbs for treating different aliments. The aim of this paper is to analyze volatile compounds of four selected species that belong to the subfamily Lamioideae, family Lamiaceae, and inspect scientifically proven biological activities and potential uses in modern phytotherapy in relation to traditional medicine...
June 7, 2023: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
#35
JOURNAL ARTICLE
Prajya Arya, Pradyuman Kumar
Fenugreek seeds are a rich source of bioactive compounds, such as diosgenin, which is one of the most crucial steroidal sapogenins emerging in the field with its spectacular health benefits. Plant-based diosgenin is bitter in taste and has remarkably low consumption levels, making it unable to fulfil the role of improving health benefits. Diosgenin is spray dried to mask bitterness and astringent flavors with two different wall materials, such as maltodextrin (MD) and whey protein concentrate (WPC), separately...
June 9, 2023: Foods (Basel, Switzerland)
#36
REVIEW
Emmanuel M Mosuka, Anushree Murugan, Abhinav Thakral, Mbelle C Ngomo, Sushil Budhiraja, Rosemarie St Victor
Over the years, the standard of care for re-alimentation of patients admitted for the treatment of anorexia nervosa (AN) has been a conservative or cautious approach described as "start low and go slow." These traditional refeeding protocols advocate for a low-calorie diet that restricts carbohydrates, with the primary goal of hypothetically lowering the risk of refeeding syndrome (RFS) and its complication. However, no consensus exists for the optimal inpatient approach to refeeding children and adolescents with AN...
May 2023: Curēus
#37
REVIEW
Insight to biotechnological utility of phycochemicals from cyanobacterium Anabaena sp.: An overview.
Chinmayee Priyadarsani Mandhata, Ajit Kumar Bishoyi, Chita Ranjan Sahoo, Sudarsan Maharana, Rabindra Nath Padhy
Cyanobacteria (blue-green algae) are well-known for the ability to excrete extra-cellular products, as a variety of cyanochemicals (phycocompounds) of curio with several extensive therapeutic applications. Among these phycocompound, the cyanotoxins from certain water-bloom forming taxa are toxic to biota, including crocodiles. Failure of current non-renewable source compounds in producing sustainable and non-toxic therapeutics led the urgency of discovering products from natural sources. Particularly, compounds of the filamentous N2 -fixing Anabaena sp...
June 19, 2023: Fitoterapia
#38
REVIEW
Marine Le Mouellic
Gastroesophageal reflux disease (GERD) in children is a frequent reason for medical consultation. It is defined as the involuntary passage of gastric contents into the esophagus, with or without regurgitation and vomiting. It can become pathological if it leads to embarrassing symptoms and complications. Often confronted with this pathology, nursery nurses sometimes find themselves at a loss when it comes to treating the symptoms of pathological GERD in a toddler, as well as in supporting the parents. In order to give them some ideas, a review of the literature on the benefits of non-medicinal strategies on regurgitation in full-term infants with pathological GERD was conducted...
2023: Soins. Pédiatrie, Puériculture
#39
JOURNAL ARTICLE
Ashley S Villatoro, Holly A Phelps, Justin B Ganjei
BACKGROUND: Bupivacaine lioposomal suspension has recently emerged in the veterinary field for local analgesia. OBJECTIVE: To describe the extra-label administration of bupivacaine liposomal suspension at the incision site of dogs undergoing limb amputation and characterize any complications. STUDY DESIGN: Nonblinded retrospective study. ANIMALS: Client-owned dogs undergoing limb amputation from 2016 to 2020. METHODS: Medical records of dogs undergoing limb amputation with concurrent use of long-acting liposomal bupivacaine suspension were reviewed for incisional complications, adverse effects, hospitalization length, and time to alimentation...
June 6, 2023: Veterinary Medicine and Science
#40
JOURNAL ARTICLE
Lorian M Taylor, Puneeta Tandon, Maitreyi Raman
Purpose: To examine the level of agreement between a patient-completed food frequency questionnaire (FFQ) and assessment of usual intake by a registered dietitian (RD) to score adherence to a Mediterranean diet (MedD) in patients with inflammatory bowel disease (IBD). Methods: Patients with IBD completed a short FFQ and were subsequently interviewed by an RD. A 12-item MedD score (MDS), adapted from the Mediterranean Diet Adherence Screener (MEDAS), was calculated from the FFQ and RD assessments. To determine agreement between individual items, Cohen's kappa coefficients were calculated...
June 2, 2023: Canadian Journal of Dietetic Practice and Research
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