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https://www.readbyqxmd.com/read/28807851/toxic-pyrrolizidine-alkaloids-provide-a-warning-sign-to-overuse-of-the-ethnomedicine-arnebia-benthamii
#1
Latif Ahmad, He Yi, Jia-Chen Hao, Andrew Semotiuk, Quan-Ru Liu, Paras Mazari
ETHNOPHARMACOLOGICAL RELEVANCE: From early times man has used medicinal plants for the treatment of various ailments and basic health care needs. The use of herbal medicines has increased day by day and with this, so do reports of adverse events, poisoning, and suspected toxicity. Similarly, the indigenous communities of Neelum Valley in Azad Kashmir commonly use Arnebia benthamii (Wall. ex G.Don) I.M.Johnst. for medicinal purposes to treat various human aliments. Besides their medicinal uses, it also contains hepatotoxic pyrrolizidine alkaloids (PAs)...
August 11, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28763004/the-linoleic-acid-dihomo-%C3%AE-linolenic-acid-ratio-la-dgla-an-emerging-biomarker-of-zn-status
#2
REVIEW
Marija Knez, James C R Stangoulis, Maria Glibetic, Elad Tako
Zinc (Zn) deficiency is a common aliment predicted to affect 17% of the world's population. Zinc is a vital micronutrient used for over 300 enzymatic reactions and multiple biochemical and structural processes in the body. Although whole blood, plasma, and urine zinc decrease in severe zinc deficiency, accurate assessment of zinc status, especially in mild to moderate deficiency, is difficult as studies with these biomarkers are often contradictory and inconsistent. Hence, as suggested by the World Health Organization, sensitive and specific biological markers of zinc status are still needed...
August 1, 2017: Nutrients
https://www.readbyqxmd.com/read/28732474/clinical-and-epidemiological-characteristics-of-pyogenic-liver-abscess-in-people-65%C3%A2-years-or-older-versus-people-under-65-a-retrospective-study
#3
Jorge Peris, Pablo Bellot, Pablo Roig, Sergio Reus, Sara Carrascosa, Gregorio González-Alcaide, José M Palazón, José M Ramos
BACKGROUND: To analyse the clinical, epidemiological, microbiological and prognostic differences of pyogenic liver abscess (PLA) in older (≥ 65 years of age) versus younger patients (< 65 years). METHODS: Multicentre, retrospective cohort study in all patients with PLA admitted to two Spanish hospitals from January 2000 to January 2014. Cases were divided into two age groups (< 65 years and ≥65 years) for comparison of clinical, epidemiological and microbiological characteristics as well as treatment...
July 21, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28719564/the-new-apgar-score-a-checklist-to-enhance-quality-of-life-in-geriatric-patients-with-hip-fracture
#4
Joseph Bernstein, Sara Weintraub, Eric Hume, Mark D Neuman, Stephen L Kates, Jaimo Ahn
For geriatric patients with hip fractures, the broken bone is the reason for admission, but only part of the overall disease. Indeed, it may be more helpful to consider the patient having geriatric hip fracture syndrome or sustaining a hip attack, as there are many associated medical, social, psychological, and other problems to which attention must be paid. To that end, we have identified a series of 10 steps, collected into a checklist, that can be undertaken for all patients with geriatric hip fracture. In homage to the maxim "we come into the world under the brim of the pelvis and go out through the neck of the femur," we defined our checklist by the acronym APGAR SCORE, named after the classic checklist of the same name used to assess a newborn child...
July 19, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28715251/body-heat-responsive-gelation-of-methylcellulose-formulation-containing-betaine
#5
Yoshiaki Shirata, Asami Wakasa, Kiyoshi Miura, Hironori Nakamura, Yoshinobu Matsumoto, Tomihiro Miyada
We examined a methylcellulose (MC) formulation that gels at body temperature for enteral alimentation. Betaine was found to have a lowering effect on the gelation temperature of the MC solution. The thermal gelation temperature of a body heat-responsive (BHR) gelling MC formulation, consisting of 2% MC, 15% glucose, 1.2% sodium citrate, and 3.5% betaine mixture, was approximately 32 °C, indicating that it could gel in response to body heat. Glucose release from the BHR gels was delayed at 37 °C in an in vitro study...
September 2017: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/28713078/-the-influence-of-pain-aliments-and-vertebral-mobility-in-patients-after-whole-body-cryotherapy
#6
Zbigniew Śliwiński, Beata Michalak, Jarosław Pasek, Grzegorz Śliwiński, Sebastian Szajkowski, Aleksander Sieroń
INTRODUCTION: The motive efficiency depends from many factors, in this currently also form the state of health. The change in grounds of vertebral column causing the limitations of mobility and pain can significance worsen the functional state, motive efficiency and quality of patient's life. The leadership of active mode of life complying to recommendations the preventive style of life as well as the using with interventions of physical medicine influences on improvement significance the state of health...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28711890/the-preexposure-prophylaxis-of-stomatological-diseases-among-the-population-of-ukraine-in-the-practice-of-the-family-doctor-and-the-pediatrician
#7
Natalia A Lyakhova, Svetlana S Kasinets
INTRODUCTION: The dental health is one of the direct measures indicators of the population's health, integrated indicator of the nation's health, its invigoration and preservation are the most important medical, social and economic problems. The aim to investigate the position and the role of a family doctor and a pediatrician in the preexposure prophylaxis orthodontic pathology among the population of Ukraine. MATERIALS AND METHODS: The book-semantic analysis of the scientific literature; the content analysis - research of the regulatory and legal framework; the system analysis - analysis of the system of doctors' carrying preexposure prophylaxis of the stomatological diseases...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28682572/carmelo-giordano-1930-2016-a-giant-in-nephrology
#8
Natale De Santo, Carlo De Pascale, Ernesto Quarto, Malcolm E Phillips, Biagio Di Iorio
Carmelo Giordano (Carmine, Louis, Joseph Giordano) was born in Naples on August 23, 1930 in the house of Rafael and Anna Tirone He received the MD cum laude in 1954. He was Fellow and assistant to Professor Flaviano Magrassi and studied nephrology at the Peter Bent Brigham Hospital, University of Harvard in Boston, under the guidance of John P. Merrill (1958-1960). He was nominated Professor of Nephrology at the University Federico II, Naples in 1975 and Professor of Medicine at the Second University of Naples (1986-2002)...
April 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28651476/molecular-mechanisms-of-intrauterine-growth-restriction
#9
Rao Gurugubelli Krishna, B Vishnu Bhat
Intrauterine growth restriction (IUGR) is a pregnancy specific disease characterized by decreased growth rate of fetus than the normal growth potential at particular gestational age. In the current scenario it is a leading cause of fetal and neonatal morbidity and mortality. In the last decade exhilarating experimental studies from several laboratories have provided fascinating proof for comprehension of molecular basis of IUGR. Atypical expression of enzymes governed by TGFβ causes the placental apoptosis and altered expression of TGFβ due to hyper alimentation causes impairment of lung function...
July 10, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28641228/relationships-between-past-and-present-pesticide-applications-and-pollution-at-a-watershed-outlet-the-case-of-a-horticultural-catchment-in-martinique-french-west-indies
#10
Charles Mottes, Magalie Lesueur Jannoyer, Marianne Le Bail, Mathilde Guéné, Céline Carles, Eric Malézieux
The understanding of factors affecting pesticide transfers to catchment outlet is still at a very early stage in tropical context, and especially on tropical volcanic context. We performed on-farm pesticide use surveys during 87 weeks and monitored pesticides in water weekly during 67 weeks at the outlet of a small catchment in Martinique. We identified three types of pollution. First, we showed long-term chronic pollution by chlordecone, diuron and metolachlor resulting from horticultural practices applied 5-20 years ago (quantification frequency higher than 80%)...
October 2017: Chemosphere
https://www.readbyqxmd.com/read/28611254/patterns-of-genetic-structure-and-linkage-disequilibrium-in-a-large-collection-of-pea-germplasm
#11
Mathieu Siol, Françoise Jacquin, Marianne Chabert-Martinello, Petr Smýkal, Marie-Christine Le Paslier, Grégoire Aubert, Judith Burstin
Pea (Pisum sativum, L.) is a major pulse crop used both for animal and human alimentation. Owing to its association with nitrogen-fixing bacteria, it is also a valuable component for low-input cropping systems. To evaluate the genetic diversity and the scale of linkage disequilibrium (LD) decay in pea, we genotyped a collection of 917 accessions, gathering elite cultivars, landraces, and wild relatives using an array of ∼13,000 single nucleotide polymorphisms (SNP). Genetic diversity is broadly distributed across three groups corresponding to wild/landraces peas, winter types, and spring types...
August 7, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28590896/social-representation-of-loud-music-in-young-adults-a-cross-cultural-study
#12
Vinaya Manchaiah, Fei Zhao, Stephen Widen, Jasmin Auzenne, Eldré W Beukes, Tayebeh Ahmadi, David Tomé, Deepthi Mahadeva, Rajalakshmi Krishna, Per Germundsson
BACKGROUND: Exposure to recreational noise, particularly music exposure, is considered one of the biggest public health hazards of our time. Some important influencing factors such as socioeconomic status, educational background, and cross-cultural perspectives have previously been found to be associated with attitudes toward loud music and the use of hearing protection. Although culture seems to play an important role, there is relatively little known about how it influences perceptions regarding loud music exposure in young adults...
June 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28545102/effect-of-dietary-restriction-and-subsequent-re-alimentation-on-the-transcriptional-profile-of-bovine-ruminal-epithelium
#13
Kate Keogh, Sinead M Waters, Paul Cormican, Alan K Kelly, Emma O'Shea, David A Kenny
Compensatory growth (CG) is utilised worldwide in beef production systems as a management approach to reduce feed costs. However the underlying biology regulating the expression of CG remains to be fully elucidated. The objective of this study was to examine the effect of dietary restriction and subsequent re-alimentation induced CG on the global gene expression profile of ruminal epithelial papillae. Holstein Friesian bulls (n = 60) were assigned to one of two groups: restricted feed allowance (RES; n = 30) for 125 days (Period 1) followed by ad libitum access to feed for 55 days (Period 2) or (ii) ad libitum access to feed throughout (ADLIB; n = 30)...
2017: PloS One
https://www.readbyqxmd.com/read/28535591/effect-of-water-stage-and-tree-stand-composition-on-spatiotemporal-differentiation-of-spring-water-chemistry-draining-carpathian-flysch-slopes-gorce-mts
#14
Michał Jasik, Stanisław Małek, Mirosław Żelazny
The purpose of this study was to identify the factors affecting spring water chemistry in different tree stands and to measure the influence of water stage on the physicochemical parameters of spring waters in a small Carpathian catchment. Water samples were collected three times per year at various stages of the water: after the spring thaw, after a period of heavy rain and after a dry period in 2011 and 2012. Water samples were left in the laboratory to reach room temperature (19-20°C) and analyzed for EC (reference T=25°C) and pH...
December 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28481841/a-system-wide-enhanced-recovery-program-focusing-on-two-key-process-steps-reduces-complications-and-readmissions-in-patients-undergoing-bowel-surgery
#15
Terrence J Loftus, Susan Stelton, Brett W Efaw, Joshua Bloomstone
Enhanced recovery programs (ERPs) can improve outcomes following bowel surgery, but implementing an ERP across a large healthcare system remains challenging. In this study, a simplified ERP that focused on two process steps, early and frequent ambulation and early alimentation, was evaluated to determine its impact on outcomes. Data were collected on 5,000 adult patients undergoing elective small and large bowel operations over a 3-year period. Complication, readmission, and mortality rates were evaluated before and after ERP implementation...
May 2017: Journal for Healthcare Quality: Official Publication of the National Association for Healthcare Quality
https://www.readbyqxmd.com/read/28479733/medicinal-plants-used-by-traditional-healers-in-jordan-the-tafila-region
#16
Abeer Abdelhalim, Talal Aburjai, Jane Hanrahan, Heba Abdel-Halim
BACKGROUND: The reporting of the medicinal plants and their traditional uses is important in order to prevent this knowledge from being lost. The aims of this study were to collect information concerning the traditional use of medicinal plants in the region of Tafila; identify the most important medicinal plants; determine the relative importance of the species surveyed; and calculate the informant consensus factor (Fic) in relation to medicinal plant use. MATERIALS AND METHODS: Data on the traditional medicinal uses of local plants were collected using qualitative tools...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28454800/rationale-and-design-of-family-based-approach-in-a-minority-community-integrating-systems-biology-for-promotion-of-health-familia
#17
RANDOMIZED CONTROLLED TRIAL
Sameer Bansilal, Rajesh Vedanthan, Jason C Kovacic, Ana Victoria Soto, Jacqueline Latina, Johan L M Björkegren, Risa Jaslow, Maribel Santana, Samantha Sartori, Chiara Giannarelli, Venkatesh Mani, Roger Hajjar, Eric Schadt, Andrew Kasarskis, Zahi A Fayad, Valentin Fuster
BACKGROUND: The 2020 American Heart Association Impact Goal aims to improve cardiovascular health of all Americans by 20% while reducing deaths from cardiovascular disease and stroke by 20%. A large step toward this goal would be to better understand and take advantage of the significant intersection between behavior and biology across the entire life-span. In the proposed FAMILIA studies, we aim to directly address this major knowledge and clinical health gap by implementing an integrated family-centric health promotion intervention and focusing on the intersection of environment and behavior, while understanding the genetic and biologic basis of cardiovascular disease...
May 2017: American Heart Journal
https://www.readbyqxmd.com/read/28431170/early-total-enteral-feeding-in-stable-very-low-birth-weight-infants-a-before-and-after-study
#18
Sushma Nangia, Amit Bishnoi, Ankita Goel, Piali Mandal, Soumya Tiwari, Arvind Saili
Background: Fear of necrotizing enterocolitis (NEC) has perpetuated delayed initiation and slow advancement of enteral feeding in very low birth weight (VLBW) infants with inherent risks of parenteral alimentation. The objective of this study was to assess effect of early total enteral feeding (ETEF) on day of achievement of full enteral feeds, feed intolerance, NEC and sepsis. Methods: In total, 208 stable VLBW neonates (28-34 weeks) admitted during 6 month periods of three consecutive years were enrolled...
April 18, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28394304/the-diet-and-haemodialysis-dyad-three-eras-four-open-questions-and-four-paradoxes-a-narrative-review-towards-a-personalized-patient-centered-approach
#19
REVIEW
Giorgina Barbara Piccoli, Maria Rita Moio, Antioco Fois, Andreea Sofronie, Lurlinys Gendrot, Gianfranca Cabiddu, Claudia D'Alessandro, Adamasco Cupisti
The history of dialysis and diet can be viewed as a series of battles waged against potential threats to patients' lives. In the early years of dialysis, potassium was identified as "the killer", and the lists patients were given of forbidden foods included most plant-derived nourishment. As soon as dialysis became more efficient and survival increased, hyperphosphatemia, was identified as the enemy, generating an even longer list of banned aliments. Conversely, the "third era" finds us combating protein-energy wasting...
April 10, 2017: Nutrients
https://www.readbyqxmd.com/read/28380145/-representation-of-self-care-of-health-at-work-among-urban-bus-drivers-in-guadalajara-mexico
#20
Mercedes Gabriela Orozco-Solis, Cecilia Colunga-Rodríguez, María de Lourdes Preciado-Serrano, Mario Ángel-González, Julio César Vázquez-Colunga, Bertha Alicia Colunga-Rodríguez
This study aimed to analyze the social representations of health self-care at work among urban bus drivers in Guadalajara, Mexico. The methodology was qualitative, with a multi-method design based on the theory of social representations. The first stage involved active observation sessions with the information recorded in field notes; in the second stage, the associative letter technique and successively hierarchized trees technique were applied to 20 drivers, submitting the data to a classical analysis of the free associations; a third stage involved semi-structured interviews with 4 drivers, submitted to content analysis...
April 3, 2017: Cadernos de Saúde Pública
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