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https://www.readbyqxmd.com/read/29457306/functional-characterization-of-collaterals-in-the-human-gingiva-by-laser-speckle-contrast-imaging
#1
Réka Fazekas, Eszter Molnár, Zsolt Lohinai, Elek Dinya, Zsuzsanna Tóth, Péter Windisch, János Vág
OBJECTIVES: The rate of blood flow between the various areas of the gingiva in resting position and under challenge is unknown. In the present study, the Laser Speckle Contrast Imaging (LSCI) method was used to map spatial and temporal changes in gingival blood flow after transient compression. METHODS: Horizontal, vertical and papilla base compressions were applied on the attached gingiva in 21 healthy patients (13 women, 8 men). LSCI was used to determine dynamic changes in regional blood flow during a five-second occlusion interval and subsequent reperfusion for twenty minutes...
February 19, 2018: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
https://www.readbyqxmd.com/read/29456888/an-observational-study-on-risk-of-secondary-cancers-in-chronic-myeloid-leukemia-patients-in-the-tki-era-in-the-united-states
#2
Vivek Kumar, Mohit Garg, Neha Chaudhary, Abhinav Binod Chandra
Introduction: The treatment with tyrosine kinase inhibitors (TKIs) has drastically improved the outcome of chronic myeloid leukemia (CML) patients. This study was conducted to examine the risk of secondary cancers (SCs) in the CML patients who were diagnosed and treated in the TKI era in the United States. Methods: The surveillance epidemiology and end results (SEER) database was used to identify CML patients who were diagnosed and received treatment during January 2002-December 2014...
2018: PeerJ
https://www.readbyqxmd.com/read/29456397/periodontal-flap-surgery-along-with-vestibular-deepening-with-diode-laser-to-increase-attached-gingiva-in-lower-anterior-teeth-a-prospective-clinical-study
#3
Ashu Bhardwaj, Zeba Jafri, Nishat Sultan, Madhuri Sawai, Anika Daing
Background: Chronic periodontitis in lower anterior teeth results in rapidly progressive gingival recession (GR), loss of alveolar bone, decreased vestibular depth (VD) with consequential tooth mobility, and tooth loss. Treatment option for such cases in this esthetically important area of the oral cavity includes extraction followed by implants for which sufficient bone height and mucogingival complex are a prerequisite. Henceforth, an attempt was made to prolong the life of lower anterior teeth and postpone the need for implants by the treatment of chronic periodontitis with periodontal flap surgery followed by vestibular deepening in single surgical procedure...
January 2018: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/29456311/management-of-fenestration-using-bone-allograft-in-conjunction-with-platelet-rich-fibrin
#4
Anuradha Bhatsange, Alkesh Shende, Sabina Deshmukh, Sharanabasappa Japatti
Fenestration and dehiscence are said to be anatomical variations of cortical bone and not true pathological entities. They represent window-like defects covered by periosteum and overlying gingiva with or without the intact marginal bone. The etiology of such defects is still unclear, though many hypotheses such as occlusal traumatism, trauma, and variation in root bone angulation have been put forward. Diagnosis of such defects is challenging clinically, and they cannot be appreciated in conventional radiographs...
July 2017: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29447319/squamous-cell-carcinoma-of-the-gingiva-mimicking-periodontal-disease-a-diagnostic-challenge-and-therapeutic-dilemma
#5
Michael M Bornstein, Claude Andreoni, Thomas Meier, Yiu Yan Leung
A case of squamous cell carcinoma of the gingiva (GSCC) in the left anterior maxilla in a 64-year-old woman that was treated for almost 5 years as suspected periodontal lesion prior to establishing the final diagnosis of oral cancer is presented in this case report. GSCCs have a variable clinical appearance, ranging from an exophytic mass to ulcerative lesions. They have been reported to pose a diagnostic challenge and are not infrequently initially misdiagnosed as periodontal disease. A delay in diagnosis and extraction of teeth in the vicinity of GSCCs has been demonstrated to increase the risk for lymph node metastasis and thus result in a lower 5-year survival rate...
March 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29445174/a-spatial-gradient-of-bacterial-diversity-in-the-human-oral-cavity-shaped-by-salivary-flow
#6
Diana M Proctor, Julia A Fukuyama, Peter M Loomer, Gary C Armitage, Stacey A Lee, Nicole M Davis, Mark I Ryder, Susan P Holmes, David A Relman
Spatial and temporal patterns in microbial communities provide insights into the forces that shape them, their functions and roles in health and disease. Here, we used spatial and ecological statistics to analyze the role that saliva plays in structuring bacterial communities of the human mouth using >9000 dental and mucosal samples. We show that regardless of tissue type (teeth, alveolar mucosa, keratinized gingiva, or buccal mucosa), surface-associated bacterial communities vary along an ecological gradient from the front to the back of the mouth, and that on exposed tooth surfaces, the gradient is pronounced on lingual compared to buccal surfaces...
February 14, 2018: Nature Communications
https://www.readbyqxmd.com/read/29440792/ancient-schwannoma-of-gingiva-a-rare-case-report
#7
Manas Bajpai, Nilesh Pardhe
Oral schwannomas (OSs) are rare benign tumors of oral cavity derived from peripheral nerve sheath, composed of proliferation of schwann cells in a characteristic pattern. AS are long-standing lesions which exhibit degenerative changes and atypia due to which they could be mistaken for malignancy. The mean age of occurrence of AS in oral cavity is 43 years, and no case of oral AS has been reported in a pediatric patient so far. Here, we present a rare case of AS of oral cavity in a 10-year-old male child.
May 2017: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29427033/a-retrospective-20-year-analysis-of-proliferative-verrucous-leukoplakia-and-its-progression-to-malignancy-and-association-with-high-risk-human-papillomavirus
#8
Jasbir D Upadhyaya, Sarah G Fitzpatrick, Mohammed N Islam, Indraneel Bhattacharyya, Donald M Cohen
Proliferative verrucous leukoplakia (PVL) is defined as an aggressive, relentless and recalcitrant form of leukoplakia that has a high propensity for malignant transformation. The aim of this study was to evaluate the malignant potential of PVL and determine its possible association with high-risk human papillomavirus (HPV). Twenty cases with a clinical and biopsy proven diagnosis of PVL were collected from the University of Florida Oral Medicine clinic database. Immunohistochemistry was performed to evaluate the expression of p16INK4A and p53 genes in the PVL lesions...
February 9, 2018: Head and Neck Pathology
https://www.readbyqxmd.com/read/29422532/type-iv-collagen-%C3%AE-6-chain-is-a-regulator-of-keratin-10-in-keratinization-of-oral-mucosal-epithelium
#9
Taishi Komori, Mitsuaki Ono, Emilio Satoshi Hara, Junji Ueda, Ha Thi Thu Nguyen, Ha Thi Nguyen, Tomoko Yonezawa, Takahiro Maeba, Aya Kimura-Ono, Takeshi Takarada, Ryusuke Momota, Kenji Maekawa, Takuo Kuboki, Toshitaka Oohashi
Keratinized mucosa is of fundamental importance to maintain healthy gingival tissue, and understanding the mechanisms of oral mucosa keratinization is crucial to successfully manage healthy gingiva. Previous studies have shown a strong involvement of the basement membrane in the proliferation and differentiation of epithelial cells. Therefore, first, to identify the keratinized mucosa-specific basement membrane components, immunohistochemical analysis for the six alpha chains of type IV collagen was performed in 8-week-old mice...
February 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29410192/patient-perceptions-and-clinical-efficacy-of-labial-frenectomies-using-diode-laser-versus-conventional-techniques
#10
Ahu Uraz, F Deniz Çetiner, Serpil Cula, Berceste Guler, Seniha Oztoprak
INTRODUCTION: The aim of present study was to compare the keratinized gingival tissue measurements, degree of subjective complaints, and functional complications of using an 980nm diode laser versus a scalpel for labial frenectomies. MATERIAL AND METHODS: Thirty-six patients requiring labial frenectomies, between 14 and 51 years old, were randomly assigned to either scalpel or diode laser treatments. The soft tissue measurements, including the keratinized gingiva width(KGW), attached gingiva width(AGW), and attached gingiva thickness(AGT), were recorded before surgery, immediately after, one week later, and one, three, and six months after surgery...
February 2, 2018: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29403236/complete-overlay-denture-for-pedodontic-patient-with-severe-dentinogenesis-imperfecta
#11
Gibi Syriac, Elizabeth Joseph, Suresh Rupesh, Josey Mathew
Dentinogenesis imperfecta (DI) is a hereditary condition that may affect both primary and permanent dentition and is characterized by abnormal dentin formation. The teeth may be discolored with chipping of enamel and, in untreated cases, the entire dentition may wear off to the gingiva. This may lead to the formation of abscesses, tooth mobility, and early loss of teeth. In the Indian population, DI is found to have an incidence of 0.09%. Treatment of DI should aim to remove infection, if any, from the oral cavity; restore form, function, and esthetics; and protect posterior teeth from wear for maintaining the occlusal vertical dimension...
October 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29403231/is-inferior-alveolar-nerve-block-sufficient-for-routine-dental-treatment-in-4-to-6-year-old-children
#12
Maryam Pourkazemi, Leila Erfanparast, Sanaz Sheykhgermchi, Milad Ghanizadeh
Introduction: Pain control is one of the most important aspects of behavior management in children. The most common way to achieve pain control is by using local anesthetics (LA). Many studies describe that the buccal nerve innervates the buccal gingiva and mucosa of the mandible for a variable extent from the vicinity of the lower third molar to the lower canine. Regarding the importance of appropriate and complete LA in child-behavior control, in this study, we examined the frequency of buccal gingiva anesthesia of primary mandibular molars and canine after inferior alveolar nerve block injection in 4- to 6-year-old children...
October 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29402326/treatment-of-gingival-defects-with-gingival-mesenchymal-stem-cells-derived-from-human-fetal-gingival-tissue-in-a-rat-model
#13
Jing Li, Shi-Qing Xu, Kai Zhang, Wen-Jian Zhang, Hong-Lin Liu, Zhen Xu, Hong Li, Jin-Ning Lou, Li-Hong Ge, Bao-Hua Xu
BACKGROUND: The study aimed to evaluate the efficacy and safety of gingival mesenchymal stem cells (GMSCs) from human fetal gingival tissue used for treating gingival defects in a rat model. METHODS: GMSCs were isolated from human fetal gingival tissue and identified by flow cytometry for nestin, Oct4, vimentin, NANOG, CD105, and CD90. The immunogenicity of GMSCs was analyzed by mixed lymphocyte reactions; the tumorigenicity of GMSCs was evaluated by xenotransplanting into nude mice...
February 5, 2018: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29401750/anti-inflammatory-effect-of-melittin-on-porphyromonas-gingivalis-lps-stimulated-human-keratinocytes
#14
Woon-Hae Kim, Hyun-Jin An, Jung-Yeon Kim, Mi-Gyeong Gwon, Hyemin Gu, Minji Jeon, Min-Kyung Kim, Sang-Mi Han, Kwan-Kyu Park
Periodontitis is a chronic inflammatory disease that contributes to the destruction of the gingiva. Porphyromonas gingivalis (P. gingivalis) can cause periodontitis via its pathogenic lipopolysaccharides (LPS). Melittin, a major component of bee venom, is known to have anti-inflammatory and antibacterial effects. However, the role of melittin in the inflammatory response has not been elucidated in periodontitis-like human keratinocytes. Therefore, we investigated the anti-inflammatory effects of melittin on a P...
February 5, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29399347/lateral-retropharyngeal-lymph-node-metastasis-from-squamous-cell-carcinoma-of-the-upper-gingiva-a-case-report
#15
Hiroshi Yamazaki, Masashi Sasaki, Ken-Ichi Aoyama, Takatsugu Suzuki, Yuya Denda, Masahiro Uchibori, Yasuhiro Nakanishi, Rena Kojima, Yoshihide Ota
Lateral retropharyngeal lymph node (LRPLN) is located between the internal carotid artery and the prevertebral muscles. Metastasis to the LRPLN is frequent in nasopharyngeal cancer, but is rare in oral cancer. The prognosis of patients with oral cancer with LRPLN metastasis is usually poor. The present study reported a patient with LRPLN metastasis from squamous cell carcinoma of the upper gingiva, who survived for >7 years. Docetaxel, cisplatin and fluorouracil (TPF) therapy was performed as induction chemotherapy and it was planned to subsequently conduct chemoradiotherapy or surgery...
January 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29399316/adjunct-use-of-low-level-laser-therapy-on-the-treatment-of-necrotizing-ulcerative-gingivitis-a-case-report
#16
Seda Sevinç Özberk, Hasan Gündoğar, Süleyman Ziya Şenyurt, Kamile Erciyas
Necrotizing ulcerative gingivitis (NUG) is a microbial disease of the gingiva in the context of an impaired host response. This form of gingivitis is relatively rare. NUG is an infection characterized by gingival necrosis presenting as "punched-out" papillae, spontaneous bleeding, pain, oral malodor, and pseudomembrane formation. The primary predisposing factors are bacterial plaque and an inadequate diet, but smoking and psychological stress may also affect the disease severity. NUG is associated with a characteristic bacterial flora, which includes fusiform bacteria, spirochetes, and Prevotella intermedia...
2018: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/29398862/tuberculous-gingival-enlargement-a-rare-clinical-manifestation
#17
Maria Subash Aaron Muthuraj, Arun Parappa Maradi, Srihari Janakiram, Koshy Chithresan
Tuberculosis (TB) is an inflammatory granulomatous disease that rarely presents as primary lesion in gingiva. Gingival involvement has been reported in only a very limited number of cases. A 13-year-old boy presented with gingival enlargement in the maxillary and mandibular anterior region associated with enlargement of lower lip with no systemic manifestations. He had a history of tuberculous lymphadenitis before 5 years which was inadequately treated. The patient's erythrocyte sedimentation rate was 70 mm/h...
March 2017: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29398861/unusual-presentation-of-familial-gingival-fibromatosis-among-male-siblings
#18
Margabandhu Manoj, Renu Garg, Kennedy Babu
Gingival enlargement refers to any increase in the size of normal gingiva. The gingiva may be enlarged in response to various interactions between the host and the environment. It can be of various types including inflammatory, drug induced, associated with systemic disease, neoplastic, false, and idiopathic. Idiopathic gingival enlargement is a rare condition of undetermined etiology. The enlargement can be localized or generalized to entire dentition and is usually associated with the emergence of the teeth into the oral cavity and may regress after extraction...
March 2017: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29398855/to-compare-the-gingival-melanin-repigmentation-after-diode-laser-application-and-surgical-removal
#19
Gaurav Mahajan, Harjit Kaur, Sanjeev Jain, Navnit Kaur, Navneet Kaur Sehgal, Aditi Gautam
Aim: The aim of the present study is to compare the gingival melanin repigmentation after diode laser application and surgical removal done by scraping with Kirkland knife. Materials and Methods: This study was a randomized split-mouth study where 10 patients presenting with unattractive, diffuse, dark brown to black gingival discoloration on the facial aspect of the maxillary gingiva were treated by diode laser application and surgical removal and followed up for 3-, 6-, and 9-month intervals...
March 2017: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29395473/application-of-radiopaque-micro-particle-fillers-for-3-d-imaging-of-periodontal-pocket-analogues-using-cone-beam-ct
#20
M Elashiry, M M Meghil, S Kalathingal, A Buchanan, R Elrefai, S Looney, M Rajendran, M Ochieng, N Young, A Elawady, R M Arce, K H Sandhage, C W Cutler
BACKGROUND: Periodontitis is an infectious/inflammatory disease most often diagnosed by deepening of the gingival sulcus, which leads to periodontal pockets (PPs) conventional manual periodontal probing does not provide detailed information on the three-dimensional (3-D) nature of PPs. OBJECTIVES: To determine whether accurate 3-D analyses of the depths and volumes of calibrated PP analogues (PPAs) can be obtained by conventional cone beam computed tomography (CBCT) coupled with novel radiopaque micro-particle fillers (described in the companion paper) injected into the PPAs...
January 29, 2018: Dental Materials: Official Publication of the Academy of Dental Materials
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