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Mood disorders

Christie Jackson, Brandon J Weiss, Marylene Cloitre
Introduction: Group Skills Training in Affective and Interpersonal Regulation (STAIR) is an evidence-based, manualized treatment for individuals with post-traumatic stress symptoms, that focuses on improving functioning through mood management (e.g., emotion regulation) and relationship skills development. To date, no study has evaluated the potential benefit of group STAIR among Veterans. Feasibility of delivering STAIR in a mixed-gender group format and the potential impact of gender on outcome were examined...
July 11, 2018: Military Medicine
S E E C Bauduin, M S van Noorden, S J A van der Werff, M de Leeuw, A M van Hemert, N J A van der Wee, E J Giltay
BACKGROUND: Specific Major Depressive Disorder (MDD) biomarkers could help improve our understanding of MDD pathophysiology and aid in the refinement of current MDD criteria. While salivary cortisol (SC) can differentiate between healthy controls and patients with psychiatric disorders, salivary alpha amylase (sAA), may be a putative candidate biomarker for MDD specifically. METHODS: In a naturalistic cohort of consecutive out-patients and healthy controls, sAA and SC were determined in 833 participants (97 MDD patients, 142 patients with other mood, anxiety, and/or somatoform (MAS-) disorders, and 594 healthy controls)...
July 6, 2018: Psychoneuroendocrinology
I Hanssen, E J Regeer, D Schut, P A Boelen
BACKGROUND: Although previous research has focused on distinguishing cognitive styles between Bipolar Disorder (BD) and Major Depressive Disorder (MDD), little is known about differences in positive affect regulation between these affective groups. The aim of the present study was to extend previous research by investigating such differences between BD and MDD, and between the bipolar subtypes (BD-I vs. BD-II and predominant polarities), using large, clinical, outpatient samples. METHODS: In total, 298 participants (96 BD-I, 27 BD-II, and 175 MDD) were included...
June 27, 2018: Comprehensive Psychiatry
Pablo Vidal-Ribas, Melissa A Brotman, Giovanni A Salum, Ariela Kaiser, Liana Meffert, Daniel S Pine, Ellen Leibenluft, Argyris Stringaris
BACKGROUND: Although severe irritability is a predictor of future depression according to recent meta-analytic evidence, other mechanisms for this developmental transition remain unclear. In this study, we test whether deficits in emotion recognition may partially explain this specific association in youth with severe irritability, defined as disruptive mood dysregulation disorder (DMDD). METHODS: Participants aged 8-20 years (M = 13.3, SD = 2.8) included youth with DMDD, split by low depressive (DMDD/LD; n = 52) and high depressive (DMDD/HD; n = 25) symptoms, and healthy controls (HC; n = 39)...
July 13, 2018: Depression and Anxiety
Evyn M Peters, Rudy Bowen, Lloyd Balbuena
OBJECTIVES: The purpose of this study was to determine whether mood instability in people with anxiety disorders contributes to trait impulsivity, non-suicidal self-injury, and binge eating/purging. METHODS: Data were analysed from a general population sample of 7,221 adults (Mage  = 51.0 years; 56.9% female). Logistic regression analyses with effect decompositions were used to establish the associations of five anxiety disorders (generalized anxiety disorder, social phobia, panic disorder, agoraphobia, and obsessive-compulsive disorder) with impulsivity, non-suicidal self-injury, and binge eating/purging, and then to determine the extent that adding mood instability to each model reduced these relationships...
July 12, 2018: Psychology and Psychotherapy
Arne Stinchcombe, Kimberley Wilson, Katherine Kortes-Miller, Lori Chambers, Bruce Weaver
OBJECTIVE: International estimates suggest the presence of health inequalities among older sexual minorities (i.e., individuals who identify as lesbian, gay, or bisexual and are 65 years old or above). In this study, we investigated the presence of health inequalities among aging lesbian and bisexual females, as well as aging gay and bisexual males in Canada. METHODS: We used baseline data from the Canadian Longitudinal Study on Aging (CLSA) Tracking and Comprehensive cohorts to cross-sectionally compare self-reported physical and mental health indicators by sex and sexual orientation...
July 12, 2018: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
Mohammad-Amin Khajezadeh, Gholamreza Zamani, Bobak Moazzami, Zahra Nagahi, Mahdie Mousavi-Torshizi, Vahid Ziaee
Objective: Systemic lupus erythematosus (SLE) is a complex autoimmune disorder characterized by multisystem involvement, including the nervous system. In the present study, we aimed to assess neuropsychiatric manifestations in juvenile-onset systemic lupus erythematosus (JSLE) in Iran. Methods: One hundred and forty-six pediatric onset patients with SLE who had registered in our pediatric rheumatology database were evaluated prospectively and cross sectionally within 2013-2015...
2018: Neurology Research International
Xiaozheng Liu, Jiuzun Chen, Bangli Shen, Gang Wang, Jiapeng Li, Hongtao Hou, Xingli Chen, Zhongwei Guo, Chuanwan Mao
Neuroimaging studies have demonstrated that major depressive disorder increases the risk of dementia in older individuals with mild cognitive impairment. We used resting-state functional magnetic resonance imaging to explore the intrinsic coupling patterns between the amplitude and synchronisation of low-frequency brain fluctuations using the amplitude of low-frequency fluctuations (ALFF) and the functional connectivity density (FCD) in 16 patients who had mild cognitive impairment with depressive symptoms (D-MCI) (mean age: 69...
2018: Neural Plasticity
Kathryn Fletcher, Fiona Foley, Neil Thomas, Erin Michalak, Lesley Berk, Michael Berk, Steve Bowe, Sue Cotton, Lidia Engel, Sheri L Johnson, Steven Jones, Michael Kyrios, Sara Lapsley, Cathrine Mihalopoulos, Tania Perich, Greg Murray
BACKGROUND: The primary objective of this randomised controlled trial (RCT) is to establish the effectiveness of a novel online quality of life (QoL) intervention tailored for people with late stage (≥ 10 episodes) bipolar disorder (BD) compared with psychoeducation. Relative to early stage individuals, this late stage group may not benefit as much from existing psychosocial treatments. The intervention is a guided self-help, mindfulness based intervention (MBI) developed in consultation with consumers, designed specifically for web-based delivery, with email coaching support...
July 13, 2018: BMC Psychiatry
Sarah Turner, Natalie Mota, James Bolton, Jitender Sareen
BACKGROUND: The comorbidity of mood and anxiety disorders (MD and AD) with substance use disorders (SUD) is common. One explanation for this comorbidity is the self-medication hypothesis, which posits that individuals with MD or AD use substances to cope with the difficult symptoms associated with the disorder. Over time, self-medication (SM) can develop into an independent SUD. This narrative review will present the prevalence and correlates of SM with alcohol and/or drugs for MD and AD and the relationship between SM and subsequent SUD using both cross-sectional and longitudinal epidemiological data...
July 12, 2018: Depression and Anxiety
Alexander R Daros, Gregory E Williams, Stefan Jung, Mustafa Turabi, Amanda A Uliaszek, Anthony C Ruocco
Individuals with borderline personality disorder (BPD) have difficulties regulating emotions, which may be a consequence of using less effective emotion regulation (ER) strategies to lessen the intensity of their negative emotions. It is not yet known whether people with BPD utilize particular ER strategies to modulate specific mood states and if these strategies are different from those used by individuals with depressive and anxiety disorders. In the present study, 90 participants (30 BPD, 30 anxiety and/or depressive disorders, and 30 healthy controls) underwent a mood induction procedure and specified which ER strategies they used and their perceived difficulty regulating mood following induction...
July 12, 2018: Personality Disorders
Lu Wang, Weiqing Liu, Xingxing Li, Xiao Xiao, Lingyi Li, Fang Liu, Yuanfang He, Yan Bai, Hong Chang, Dong-Sheng Zhou, Ming Li
Genome-wide association studies suggest that rs1064395 in the neurocan gene ( NCAN ) is a potential risk factor for bipolar disorder (BPD), and further replication analyses in larger independent samples are needed. We herein analyzed rs1064395 in a Han Chinese sample of 1,146 BPD cases and 2,031 controls, followed by a meta-analysis of BPD samples from worldwide populations including a total of 15,318 cases and 91,990 controls. The meta-analysis found that rs1064395 showed a genome-wide significant association with BPD ( p = 4...
June 2018: Molecular Neuropsychiatry
Amr Mounir, Mohamed Gamal Elghobaier, Abdelrahim Abdrabou Sadek, Amr Ahmed Othman
Self-inflicted eye trauma is a serious form of self-harm as it may lead to irreversible visual disability. Diagnosing self-inflicted ocular injuries, in all its forms, can be quite challenging. In this report, we are presenting a 5-year-old girl presented to Sohag University Outpatient Clinic with a history of repeated attacks of bilateral eye redness with blood-tinged strands removed from her eyes. After ocular examination, inferior bulbar conjunctival injection with blood-tinged strands were found. After careful examination of the strands, it was discovered that they were actual threads of cloth due to self-inflicted eye injury...
May 2018: Electronic Physician
Ronak Mihan, Zahra Shahrivar, Javad Mahmoudi-Gharaei, Alia Shakiba, Mostafa Hosseini
Objective: Attention-deficit hyperactivity disorder (ADHD) is common in adulthood, and it is associated with different high- risk behaviors, particularly substance use. Evidence suggests a high prevalence of ADHD in adults who take methamphetamine (METH). This study aimed at comparing functional level, quality of life, and psychiatric comorbidities in METH users with and without adult ADHD (A-ADHD). Method : In this cross-sectional study, 134 patients who had a history of METH use (at least once in lifetime) were selected from among inpatient and outpatient referrals to a psychiatric hospital...
April 2018: Iranian Journal of Psychiatry
Ricardo Azziz
Polycystic ovary syndrome (PCOS) is a highly prevalent disorder, representing the single most common endocrine-metabolic disorder in reproductive-aged women. Currently there are four recognized phenotypes of PCOS: 1) hyperandrogenism+oligo-anovulation+polycystic ovarian morphology; 2) hyperandrogenism+oligo-anovulation; 3) hyperandrogenism+polycystic ovarian morphology; and 4) oligo-anovulation+polycystic ovarian morphology, each with different long-term health and metabolic implications. Clinicians should clearly denote a patient's phenotype when making the diagnosis of PCOS...
July 10, 2018: Obstetrics and Gynecology
Ane Alberdi Aramendi, Alyssa Weakley, Maureen Schmitter-Edgecombe, Diane Joyce Cook, Asier Aztiria Goenaga, Adrian Basarab, Maitane Barrenechea Carrasco
As members of an increasingly aging society, one of our major priorities is to develop tools to detect the earliest stage of age-related disorders such as Alzheimer's Disease (AD). The goal of this paper is to evaluate the possibility of using unobtrusively collected activity-aware smart home behavior data to detect the multimodal symptoms that are often found to be impaired in AD. After gathering longitudinal smart home data for 29 older adults over an average duration of >2 years, we automatically labeled the data with corresponding activity classes and extracted time-series statistics containing 10 behavioral features...
January 25, 2018: IEEE Journal of Biomedical and Health Informatics
Meha Qassem, Loukas Constantinou, Iasonas Triantis, Michelle Hickey, Eleni Palazidou, Panayiotis A Kyriacou
GOAL: Lithium preparations are considered the most reliable mood stabilizers for patients with Bipolar Disorder (BD), and are the most effective at reducing the risk of suicide. However, maintaining blood lithium concentration within the narrow therapeutic range of 0.4-1.2 mEq is crucial but extremely difficult. The aim of this work is to develop a personal lithium blood level analyzer using a novel method of combined optical and electrical impedance spectroscopy to test micro volumes of spiked samples of human blood...
May 14, 2018: IEEE Transactions on Bio-medical Engineering
Helen Ramsbottom, Lisa Collier Farmer
PROBLEM: Less than 30-day readmission has become a national problem. This pediatric medical center discovered that the primary diagnosis of Mood Disorder, not otherwise specified, was the third most common readmission diagnosis hospital-wide. Administration actively sought a resolution to less-than-30-day readmissions because All-Patient-Refined-Diagnostic-Related Groups would soon include pediatric hospitals with reimbursement impact. METHODS: The Iowa Model for evidence-based practice framed the work of case management to identify readmission risk, reduce readmissions, and improve patient quality...
July 10, 2018: Journal of Child and Adolescent Psychiatric Nursing
Oana A David, Roxana A I Cardoș, Silviu Matu
Therapeutic games represent a promising solution for addressing emotional difficulties in youths. The aim of the present study was to investigate the effectiveness of the REThink game, in helping children and adolescents, to develop psychological resilience. Therefore, 165 children aged between 10 and 16 years were randomly assigned in one of the three groups: 54 participants in the REThink condition, 55 participants in the Rational Emotive Behavior Education condition, and 56 participants in the waitlist condition...
July 10, 2018: European Child & Adolescent Psychiatry
Patricia Louie, Blair Wheaton
The tendency for Blacks to report similar or lower rates of mental disorder than Whites is well-established. However, whether these disparities are stable across cohorts of Black and White Americans is not well understood. In the current study, we examined Black-White differences in the lifetime prevalence of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition mood, anxiety, impulse control, substance use and any disorders across 3 cohorts of Blacks and Whites aged 4 to 18. Using merged data from the National Comorbidity Survey Replication (2001-2003) and the National Comorbidity Survey Adolescent Supplement (2001-2004), we observed a change in the Black-White patterning of mental disorder between 1957 and 2004...
July 9, 2018: American Journal of Epidemiology
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