keyword
https://read.qxmd.com/read/38544600/comparison-of-outcomes-between-milrinone-and-dobutamine-in-patients-with-cardiogenic-shock-a-meta-analysis-of-randomized-control-trials-and-observational-studies
#21
REVIEW
Chenyue Fan, Calvin R Wei, Neelum Ali
The aim of this systematic review and meta-analysis was to compare the outcomes between milrinone and dobutamine in patients with cardiogenic shock. The search strategy involved a comprehensive exploration of electronic databases, including PubMed, EMBASE, Cochrane Library, and Scopus from the the inception of each database up to the 31st of January 2024. A combination of keywords and Medical Subject Headings (MeSH) terms was employed to identify relevant studies. The outcomes assessed in this meta-analysis included all-cause in-hospital mortality, length of intensive care unit (ICU stay), and length of hospital stay...
February 2024: Curēus
https://read.qxmd.com/read/38544522/the-impacts-of-laparoscopic-restorative-proctocolectomy-for-ulcerative-colitis-systematic-review-and-meta-analysis
#22
REVIEW
Motoi Uchino, Hiroki Ikeuchi, Yuki Horio, Ryuichi Kuwahara, Kurando Kusunoki, Kentaro Nagano, Kei Kimura, Kozo Kataoka, Naohito Beppu, Masataka Ikeda
INTRODUCTION: Laparoscopic surgery (LAP) is now recognized as the standard procedure for colorectal surgery. However, the standard surgery for ulcerative colitis (UC) is total proctocolectomy with ileal pouch anal anastomosis (IPAA), which may be an overly complex procedure to complete laparoscopically. We conducted this systematic review and meta-analysis to evaluate the efficacy as well as the advantages and disadvantages of LAP-IPAA in patients with UC stratified by the outcome of interest...
2024: Inflammatory Intestinal Diseases
https://read.qxmd.com/read/38543096/effect-of-botulinum-toxin-injections-in-the-treatment-of-spasticity-of-different-etiologies-an-umbrella-review
#23
REVIEW
Iris Otero-Luis, Arturo Martinez-Rodrigo, Iván Cavero-Redondo, Nerea Moreno-Herráiz, Irene Martínez-García, Alicia Saz-Lara
BACKGROUND: Spasticity is a very common neurological sequelae that significantly impacts the quality of life of patients, affecting more than 12 million people worldwide. Botulinum toxin is considered a reversible treatment for spasticity, but due to the large amount of available evidence, synthesis seems necessary. Therefore, we conducted an overview of existing systematic reviews and meta-analyses to evaluate the effect of botulinum toxin injections in the treatment of spasticity of different etiologies...
February 28, 2024: Pharmaceuticals
https://read.qxmd.com/read/38542743/plant-derived-substances-for-prevention-of-necrotising-enterocolitis-a-systematic-review-of-animal-studies
#24
REVIEW
Cheryl Anne Mackay, Chandra Rath, Shripada Rao, Sanjay Patole
Inflammation, oxidative injury, and gut dysbiosis play an important role in the pathogenesis of necrotising enterocolitis (NEC). Plant-derived substances have historically been used as therapeutic agents due to their anti-inflammatory, antioxidant, and antimicrobial properties. We aimed to review pre-clinical evidence for plant-derived substances in the prevention and treatment of NEC. A systematic review was conducted using the following databases: PubMed, EMBASE, EMCARE, MEDLINE and Cochrane Library (PROSPERO CRD42022365477)...
March 14, 2024: Nutrients
https://read.qxmd.com/read/38542225/efficacy-of-cold-atmospheric-plasma-vs-chemotherapy-in-triple-negative-breast-cancer-a-systematic-review
#25
REVIEW
Catarina Almeida-Ferreira, Carlos Miguel Marto, Chrislaura Carmo, Joana Almeida-Ferreira, Cristina Frutuoso, Maria João Carvalho, Maria Filomena Botelho, Mafalda Laranjo
Breast cancer is a growing disease, with a high worldwide incidence and mortality rate among women. Among the various types, the treatment of triple-negative breast cancer (TNBC) remains a challenge. Considering the recent advances in cold atmospheric plasma (CAP) cancer research, our goal was to evaluate efficacy data from studies based on chemotherapy and CAP in TNBC cell lines and animal models. A search of the literature was carried out in the PubMed, Web of Science, Cochrane Library, and Embase databases...
March 13, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38542036/sexualized-drug-use-and-chemsex-among-men-who-have-sex-with-men-in-europe-a-systematic-review-and-meta-analysis
#26
REVIEW
Marina Coronado-Muñoz, Emilio García-Cabrera, Angélica Quintero-Flórez, Encarnación Román, Ángel Vilches-Arenas
Background: In recent years, in Europe, there has been a growing concern about the use of sexualized drugs among men who have sex with men (MSM), due to its possible link to an increase in sexually transmitted infections. The aim of this review is to study the prevalence of chemsex, and the sexualized drug used in Europe, describing both different consumption patterns and other sexual behaviors considered risky and their possible relationship with positivity in diagnoses of sexually transmitted infections, including human immunodeficiency virus...
March 21, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38542022/the-role-of-postoperative-radiotherapy-in-the-management-of-dermatofibrosarcoma-protuberans-a-multidisciplinary-systematic-review
#27
REVIEW
Bruno Fionda, Antonella Loperfido, Alessandro Di Stefani, Valentina Lancellotta, Andrea Paradisi, Martina De Angeli, Simone Cappilli, Ernesto Rossi, Anna Amelia Caretto, Tiziano Zinicola, Giovanni Schinzari, Stefano Gentileschi, Alessio Giuseppe Morganti, Agata Rembielak, Ketty Peris, Luca Tagliaferri
Background : Dermatofibrosarcoma protuberans (DFSP) is a superficial soft tissue sarcoma, and surgical excision is the first-line treatment. The aim of this systematic review is to provide an update about the current indications and clinical results regarding the use of postoperative radiotherapy in DSFP, considering both adjuvant and salvage setting. Methods : We conducted a systematic literature review using the main scientific database, including Cochrane library, Scopus, and PubMed, for any relevant article about the topic, and we considered all available papers without any time restriction...
March 21, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38542014/dermoscopy-of-umbilical-lesions-a-systematic-review
#28
REVIEW
Jakub Żółkiewicz, Martyna Sławińska, Urszula Maińska, Roman J Nowicki, Michał Sobjanek, Luc Thomas
Background : The umbilicus is a fibrous remnant located in the centre of the abdomen. Various entities may be encountered in this special anatomical location; however, little is known about their dermoscopic presentation. The aim of this study was to provide a comprehensive summary of existing evidence on dermoscopic features of umbilical lesions. Methods : Studies assessing dermoscopic images of umbilical lesions were included in this study. No age, ethnicity or skin phototype restrictions were applied. Papers assessing lesions outside of the umbilical area, lacking dermoscopic images and/or dermoscopic description and not related to the topic were excluded...
March 20, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38542011/the-impact-of-regional-anesthesia-in-masking-acute-compartment-syndrome-after-limb-trauma
#29
REVIEW
Nicole Hilber, Anna Dodi, Stephan Blumenthal, Heinz Bruppacher, Alain Borgeat, José Aguirre
Regional anesthesia has shown to be successful in controlling major pain in trauma patients. However, the possibility of masking acute compartment syndrome (ACS) after peripheral nerve blocks for limb injuries is still controversially discussed. Therefore, we aimed to summarize the current literature regarding this topic to shed light on the impact of peripheral regional anesthesia on the diagnosis of ACS in trauma patients. We searched Pubmed, Google Scholar and the Cochrane Library for literature following the PRISMA (preferred reporting items for systematic reviews and meta-analyses) guidelines...
March 20, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541970/efficacy-and-safety-of-rho-kinase-inhibitors-vs-beta-blockers-in-primary-open-angle-glaucoma-a-systematic-review-with-meta-analysis
#30
REVIEW
Brenda Nana Wandji, Noélie Bacq, Adèle Ehongo
Background: In order to support the positioning of Rho kinase inhibitors (Rhokis) in the European market for the treatment of glaucoma, scientific evidence comparing the efficacy and safety of Rhokis and beta-blockers (β-βs) in the treatment of open-angle glaucoma after 3 months was assembled through a systematic review and meta-analysis (meta-A) of randomized controlled trials (RCTs). Methods: Relevant articles were searched for on PubMed, EMBASE, and the Cochrane Library. Of the 251 articles found, three met all eligibility criteria...
March 18, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541964/waist-circumference-and-body-mass-index-as-predictors-of-disability-progression-in-multiple-sclerosis-a-systematic-review-and-meta-analysis
#31
REVIEW
Vasileios Giannopapas, Maria-Ioanna Stefanou, Vassiliki Smyrni, Dimitrios K Kitsos, Maria Kosmidou, Sophia Stasi, Athanasios K Chasiotis, Konstantina Stavrogianni, Georgia Papagiannopoulou, John S Tzartos, George P Paraskevas, Georgios Tsivgoulis, Sotirios Giannopoulos
Background: While obesity has been shown to elevate the risk of developing multiple sclerosis (MS), there is a lack of strong evidence regarding its role in the disability progression and status of MS patients. Methods: This systematic review and meta-analysis aimed to provide comparative estimates of WC and BMI in patients with MS (PwMS) and to investigate potential associations between the waist circumference (WC) and body mass index (BMI) and demographic and specific MS characteristics. Adhering to PRISMA guidelines, a detailed search of the MEDLINE PubMed, Cochrane Library, and Scopus databases was conducted...
March 18, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541856/coping-strategies-and-inflammatory-bowel-disease-a-narrative-review
#32
REVIEW
Stefan L Popa, Mihaela Fadgyas Stanculete, Simona Grad, Vlad Dumitru Brata, Traian-Adrian Duse, Andrei-Vlad Badulescu, Raquel-Vanessa Dragan, Paolo Bottalico, Cristina Pop, Abdulrahman Ismaiel, Daria-Claudia Turtoi, Dinu Iuliu Dumitrascu, Cristina Pojoga, Claudia Gherman, Liliana David
Background : Coping strategies play a crucial role in managing inflammatory bowel disease (IBD), influencing both health-related quality of life (HRQoL) and psychological well-being. This study systematically reviews the available literature to analyze coping mechanisms in IBD populations and their impact. Methods : Relevant English-language studies published until 2023 were identified through a comprehensive search of PubMed, EMBASE, EBSCOhost, and Cochrane Library. After applying inclusion and exclusion criteria, 57 articles underwent full analysis...
March 12, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541212/microrna-expression-in-endometrial-cancer-current-knowledge-and-therapeutic-implications
#33
REVIEW
Irene Iavarone, Rossella Molitierno, Pietro Fumiento, Maria Giovanna Vastarella, Stefania Napolitano, Maria Teresa Vietri, Pasquale De Franciscis, Carlo Ronsini
Background and Objectives : An extracellular vesicle is part of a class of submicron particles derived from cells, mediating cellular crosstalk through microRNA (miRNA). MiRNA is a group of RNA molecules, each of which consists of 15-22 nucleotides and post-transcriptionally modulates gene expression. The complementary mRNAs-onto which the miRNAs hybridize-are involved in processes such as implantation, tumor suppression, proliferation, angiogenesis, and metastasis that define the entire tumor microenvironment...
March 15, 2024: Medicina
https://read.qxmd.com/read/38541204/relationship-between-xpa-xpb-ercc3-xpf-ercc4-and-xpg-ercc5-polymorphisms-and-the-susceptibility-to-head-and-neck-carcinoma-a-systematic-review-meta-analysis-and-trial-sequential-analysis
#34
REVIEW
Mohammad Moslem Imani, Masoumeh Basamtabar, Sattar Akbari, Edris Sadeghi, Masoud Sadeghi
Background and Objectives : Nucleotide Excision Repair (NER), the most extensively researched DNA repair mechanism, is responsible for repairing a variety of DNA damages, and Xeroderma Pigmentosum (XP) genes participate in NER. Herein, we aimed to update the previous results with a meta-analysis evaluating the association of XPA, XPB/ERCC3, XPF/ERCC4, and XPG/ERCC5 polymorphisms with the susceptibility to HNC. Materials and Methods : PubMed/Medline, Web of Science, Scopus, and Cochrane Library databases were searched without any restrictions until 18 November 2023 to find relevant studies...
March 14, 2024: Medicina
https://read.qxmd.com/read/38541053/safety-and-efficacy-of-the-use-of-supraglottic-airway-devices-in-children-and-adolescents-undergoing-adenotonsillectomy-a-systematic-review-and-meta-analysis
#35
REVIEW
Abhijit Nair, Nitinkumar Borkar, Sunil Subhash Murke, Ujjwalraj Dudhedia
(1) Background: Supraglottic airway devices (SAD) have been used in children and adolescents undergoing adenotonsillectomies under general anesthesia. This systematic review and meta-analysis investigate the safety and efficacy of using SADs when compared to an endotracheal tube (ETT). (2) Methods: After registering with PROSPERO, databases like PubMed, Scopus, OviD, CINAHL, and Cochrane Library were searched using relevant keywords from the year 2000. We used RoB-2 for risk-of-bias assessment, GRADE for assessing the quality of evidence, RevMan 5...
March 16, 2024: Journal of Personalized Medicine
https://read.qxmd.com/read/38541045/do-patients-with-benign-paroxysmal-positional-vertigo-have-a-higher-prevalence-of-osteoporosis-a-systematic-review-and-meta-analysis
#36
REVIEW
Chul-Ho Kim, Keunho Kim, Yeonjoo Choi
Benign paroxysmal positional vertigo (BPPV) is a common vestibular disorder characterized by episodic vertigo. BPPV primarily affects older adults. Thus, understanding the potential relationship between BPPV and osteoporosis is clinically important. We performed a systematic search of MEDLINE (PubMed), Embase, and Cochrane Library databases for studies on the risk of osteoporosis between BPPV (+) and BPPV (-) groups up until 17 April 2023. We compared osteoporosis prevalence between groups and performed subgroup analyses for male, female, and older patients (aged ≥ 55 years)...
March 13, 2024: Journal of Personalized Medicine
https://read.qxmd.com/read/38541003/advancing-the-management-of-skull-base-chondrosarcomas-a-systematic-review-of-targeted-therapies
#37
REVIEW
Edoardo Agosti, Marco Zeppieri, Sara Antonietti, Tamara Ius, Marco Maria Fontanella, Pier Paolo Panciani
BACKGROUND: Chondrosarcomas rank as the second most common primary bone malignancy. Characterized by the production of a cartilaginous matrix, these tumors typically exhibit resistance to both radiotherapy (RT) and chemotherapy (CT), resulting in overall poor outcomes: a high rate of mortality, especially among children and adolescents. Due to the considerable resistance to current conventional therapies such as surgery, CT, and RT, there is an urgent need to identify factors contributing to resistance and discover new strategies for optimal treatment...
February 28, 2024: Journal of Personalized Medicine
https://read.qxmd.com/read/38540726/reproductive-and-oncologic-outcomes-in-young-women-with-stage-ia-and-grade-2-endometrial-carcinoma-undergoing-fertility-sparing-treatment-a-systematic-review
#38
REVIEW
Andrea Etrusco, Antonio Simone Laganà, Vito Chiantera, Mislav Mikuš, Hafiz Muhammad Arsalan, Antonio d'Amati, Amerigo Vitagliano, Ettore Cicinelli, Alessandro Favilli, Antonio D'Amato
BACKGROUND: Endometrial cancer (EC) is the most common gynecological malignancy in both Europe and the USA. Approximately 3-5% of cases occur in women of reproductive age. Fertility-sparing treatment (FST) options are available, but very limited evidence regarding grade 2 (G2) ECs exists in the current literature. This systematic review aimed to comprehensively evaluate reproductive and oncologic outcomes among young women diagnosed with stage IA or G2EC disease who underwent FST. METHODS: A comprehensive search of the literature was carried out on the following databases: MEDLINE, EMBASE, Global Health, The Cochrane Library (Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, Cochrane Methodology Register), the Health Technology Assessment Database, and Web of Science...
March 5, 2024: Biomolecules
https://read.qxmd.com/read/38540665/aquatic-exercise-in-physical-therapy-treatment-for-fibromyalgia-systematic-review
#39
REVIEW
Manuel Rodríguez-Huguet, Carmen Ayala-Martínez, Pablo Góngora-Rodríguez, Miguel Ángel Rosety-Rodríguez, Rocío Martín-Valero, Jorge Góngora-Rodríguez
Fibromyalgia is a chronic condition characterized by musculoskeletal pain. The aim of this study was to synthesize scientific evidence on the effects of aquatic exercise programs on pain and quality of life in individuals with fibromyalgia. This review was carried out using the following databases in January 2024: Cochrane Library, PEDro, PubMed, SCOPUS, and Web of Science. Four clinical trials focusing on aquatic exercise as a treatment for patients with fibromyalgia were selected. These trials were published in English between 2019 and 2024...
March 21, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38540643/is-craniosacral-therapy-effective-a-systematic-review-and-meta-analysis
#40
REVIEW
Luis Ceballos-Laita, Edzard Ernst, Andoni Carrasco-Uribarren, Sara Cabanillas-Barea, Jaime Esteban-Pérez, Sandra Jiménez-Del-Barrio
OBJECTIVES: The aim of this study was to evaluate the clinical effectiveness of craniosacral therapy (CST) in the management of any conditions. METHODS: Two independent reviewers searched the PubMed, Physiotherapy Evidence Database, Cochrane Library, Web of Science, and Osteopathic Medicine Digital Library databases in August 2023, and extracted data from randomized controlled trials (RCT) evaluating the clinical effectiveness of CST. The PEDro scale and Cochrane Risk of Bias 2 tool were used to assess the potential risk of bias in the included studies...
March 18, 2024: Healthcare (Basel, Switzerland)
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