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Parotid enlargement in children

Danny Jandali, Ashley Heilingoetter, Ritu Ghai, Jill Jeffe, Samer Al-Khudari
Background: Lipoblastomas are rare benign neoplasms that arise from fetal white fat cells. They are typically found in children under the age of 3 and have been reported in the mediastinum, extremities, and infrequently in the head and neck. We present a rare case of a lipoblastoma arising from the parotid gland and the first known report of a parotid lipoblastoma in a teenager. Case presentation: A 15-year-old male presented with a painless, slowly enlarging parotid mass and left facial swelling...
2018: Frontiers in Pediatrics
I Majdoub, S Kallel, M Hsairi, M Snoussi, M Charfi, A Ben Halima, A Frikha, M Weli, F Safi, L Gargouri, N Ben Halima, A Mahfoudh, A Ghorbel, Z Bahloul
Sjögren syndrome is uncommon in children and occurs most often in association with autoimmune diseases (secondary Sjögren syndrome). We describe the clinical and biological features of a 7-year-old girl with primary Sjögren syndrome revealed by recurrent parotiditis. CASE REPORT: A 7-year-old girl was referred for investigation of multiple episodes of parotid swelling since age 4 years, without systemic symptoms. The examination was unremarkable except for enlarged and painless parotid glands...
December 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
J Hu, J L Xie, Z J Zhou, X G Zhou
Objective: To investigate the pathological features and clinical manifestations of mucosa-associated lymphoid tissue (MALT) lymphoma in children and adolescents. Methods: Five cases of MALT lymphoma in children were investigated by morphology and immunophenotyping along with clinical follow-up. Results: Five cases of MALT lymphoma occurred in the antrum, orbit, parotid gland and nasopharynx. All patients had no B symptoms and only one patient showed a local mass with ulcer. One case presented with cervical lymph node enlargement, and 4 cases showed no evidence of lymphadenopathy...
September 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
Latha Magatha Sneha, Kaarthikeyani Sankaravadivelu Subbiah, Julius Xavier Scott, Aruna Rajendiran
The more common causes of parotid enlargement in children are infections and inflammatory conditions. Primary neoplasms of the parotid glands are rare in pediatric age group; however, secondary malignancies have been reported in survivors of childhood leukemia. The parotid glands have been the sites of relapses in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia. However, bilateral parotid involvement as an initial presentation of ALL is rarely reported. We present a case of an 8-year-old boy who presented with bilateral parotid enlargement as an initial manifestation of ALL...
January 2017: National Journal of Maxillofacial Surgery
A Agaimy, H Iro, J Zenk
Salivary gland tumors and tumor-like lesions in the pediatric population are uncommon. They comprise a heterogeneous group of infectious/inflammatory and neoplastic conditions. Pediatric salivary neoplasms include benign tumors of mesenchymal or epithelial origin as well as malignancies of epithelial (carcinomas), mesenchymal (sarcoma) or hematolymphoid (lymphoma) derivation. Infectious/inflammatory conditions and hematolymphoid malignancies may represent either genuine parenchymal pathology or conditions involving intraglandular lymph nodes of the parotid glands (intraglandular lymphadenopathy and intraglandular nodal lymphomas)...
July 2017: Der Pathologe
Céleste Rebours, Vincent Couloigner, Louise Galmiche, Odile Casiraghi, Cécile Badoual, Sabah Boudjemaa, Anthony Chauvin, Monique Elmaleh, Brice Fresneau, Sylvie Fasola, Erea-Noël Garabédian, Thierry Van Den Abeele, Daniel Orbach
OBJECTIVES/HYPOTHESIS: To analyze clinical presentations, treatment modalities, and evolution of pediatric cases of salivary gland carcinomas to standardize care for these rare diseases. STUDY DESIGN: Multicentric, retrospective study. METHODS: We included in this retrospective study all children and adolescents (aged ≤18 years) treated from 1992 to 2012 in six pediatric centers in Paris, France. Pathological tumor specimens of these cases were reviewed...
January 2017: Laryngoscope
Brittany E Goldberg, Emmanuel F Mongodin, Cheron E Jones, Michelle Chung, Claire M Fraser, Anupama Tate, Steven L Zeichner
The oral microbial community (microbiota) plays a critical role in human health and disease. Alterations in the oral microbiota may be associated with disorders such as gingivitis, periodontitis, childhood caries, alveolar osteitis, oral candidiasis and endodontic infections. In the immunosuppressed population, the spectrum of potential oral disease is even broader, encompassing candidiasis, necrotizing gingivitis, parotid gland enlargement, Kaposi's sarcoma, oral warts and other diseases. Here, we used 454 pyrosequencing of bacterial 16S rRNA genes to examine the oral microbiome of saliva, mucosal and tooth samples from HIV-positive and negative children...
2015: PloS One
Takako Inaba, Yuki Fukumura, Tsuyoshi Saito, Junkichi Yokoyama, Shinichi Ohba, Atsushi Arakawa, Takashi Yao
Mammary analogue secretory carcinoma (MASC) is a recently recognized tumor of salivary glands characterized by the ETV6-NTRK3 fusion gene. This tumor is very rare in children and adolescents. We report a case of MASC in a 15-year-old girl, the fifth youngest case so far reported. The patient complained of a left infra-auricular mass that gradually enlarged for a year. Fine-needle aspiration cytology/imprint cytology showed individual tumor cells that had faintly eosinophilic granular cytoplasm with secretion granules sometimes seen adjacent to the tumor cells...
2015: Case Reports in Pathology
Abraham Gedalia, Tahir A Khan, Avinash K Shetty, Victoria R Dimitriades, Luis R Espinoza
A retrospective chart review was conducted to detect patients with sarcoidosis seen by pediatric rheumatology service from the period of 1992 to 2013 at Children's hospital of New Orleans. Twenty-seven patients were identified. The average duration of symptoms before diagnosis was 5 (range 1-120) months. Five patients had onset before the age of 5 years and were diagnosed with early-onset sarcoidosis. The most common manifestations at presentation were constitutional symptoms (62 %) followed by ocular (38 %)...
July 2016: Clinical Rheumatology
Inês Beatriz da Silva Rath, Ana Paula C A Beltrame, Aroldo P Carvalho, Marcela B Schaeffer, Izabel C S Almeida
OBJECTIVES: This work aimed at studying the salivary gland disease (SGD) as it relates to associated factors, such as persistent generalised lymphadenopathy (PGL), lymphocytic interstitial pneumonia (LIP), clinical and immunological features of AIDS, and salivary flow rate and pH, as well as at exploring the relationship between the clinical diagnosis and the imaging diagnosis by ultrasound (US) examination of the parotid glands. METHODS: Information regarding the observation of parotid gland enlargement, PGL, LIP, and clinical and immunological features of AIDS was gathered from medical records, and a saliva sample for unstimulated salivary flow rate and pH measurement was collected from 142 children aged 3 through 10 years treated at the Department of Infectious Diseases of Joana de Gusmão Children's Hospital, Florianópolis, SC, Brazil...
July 2015: International Journal of Paediatric Dentistry
Chandrika Azad, Adhi Arya, Vidushi Mahajan, Shilpa Goyal
BACKGROUND: Early onset sarcoidosis is a rarely reported disease in children. CASE CHARACTERISTICS: 2½-year-old girl with chronic enlargement of bilateral parotid glands and polyarthritis. OBSERVATION: Biopsy of salivary gland revealed non-caseating granuloma. OUTCOME: Polyarthritis and salivary gland swelling resolved completely after starting oral corticosteroids. MESSAGE: Sarcoidosis is an important differential diagnosis in young children with joint and salivary gland involvement...
August 2014: Indian Pediatrics
Bamidele M Kolude, Regina E Oladokun
OBJECTIVES: To establish the significance of parotid enlargement, state frequency, cytological features and effect of antiretroviral therapy (ART) on parotid enlargement among a pediatric HIV population. STUDY DESIGN: A 6 month cross sectional survey that utilised clinical features, serial immunological indices and fine needle aspiration cytology. RESULTS: 287 HIV positive children were seen at special paediatric clinic of the University College Hospital, Ibadan, Nigeria, 114 (39...
2013: Journal of Clinical Pediatric Dentistry
B Pramod Krishna
Salivary gland tumours are rare in childhood, and almost all of them occur in parotid gland. Minor salivary gland tumours are even rarer, pleomorphic adenoma being the most frequently found tumour. Only seventeen cases of pleomorphic adenoma arising in the minor salivary gland tumour have been reported in children and adolescents. Pleomorphic adenoma of minor salivary gland represents about 45% of all the tumours of the minor salivary glands. Pleomorphic adenoma is slowly enlarging tumour indistinguishable from adenoid cystic carcinoma clinically, except for pain and ulceration, which is more common in the latter...
June 2013: Journal of Maxillofacial and Oral Surgery
Aniket Saha, Smita Dandekar, Sarah Milla, Elizabeth Roman, Teena Bhatla
Acute lymphoblastic leukemia (ALL) in infants below 1 year of age accounts for 2.5% to 5% of childhood ALL. Most children with ALL present with fever, bruising, mucosal bleeding, bone pain, pallor, hepatosplenomegaly, and lymphadenopathy. Common sites of extramedullary involvement at diagnosis include liver, spleen, lymph nodes, brain, and testes. Nephromegaly has also been reported. We present a novel case of bilateral parotid enlargement along with bilateral palpable nephromegaly in a patient with newly diagnosed infant ALL...
April 2014: Journal of Pediatric Hematology/oncology
Eileen McCarthy, Alistair R M Cobb
A case is presented of a 14-year-old female undergoing orthodontic fixed appliance treatment who presented with right facial swelling in the parotid region. An initial diagnosis of acute infective parotitis was made by her primary care clinician. However, after clinical examination and ultrasonographic imaging, a diagnosis of salivary stasis secondary to inflammatory occlusion of Stensen's ductal orifice was made. The ductal orifice had been traumatized by the adjacent orthodontic appliance. This has not been described before in the literature...
December 2012: Journal of Orthodontics
Gretchen C Banks, Daniel J Kirse, Evelyn Anthony, Simon Bergman, Avinash K Shetty
The differential diagnosis of bilateral parotid gland enlargement in children includes infectious, inflammatory, and neoplastic disorders. We present the case of a 13-year-old male who presented with a 5-week history of bilateral parotid swelling. On exam, both parotid glands were nontender, smooth, and diffusely enlarged. He had slightly elevated inflammatory markers, but other lab results were normal. A neck CT revealed symmetric enlargement of the parotid, submandibular, and sublingual glands. A chest CT revealed scattered peripheral pulmonary nodules and bilateral hilar adenopathy...
March 2013: American Journal of Otolaryngology
Yang Wen, Hyun Woo Goo
Sialadenosis is characterized by asymptomatic bilateral enlargement of the parotid glands. It is uncommon, especially in children. Diagnosis and analysis of sialadenosis based on imaging modalities have been rarely reported. Here, we report a case of sialadenosis in a child with leukemia, in which the diagnosis was made based on sonography and CT findings.
September 2012: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
Toru Igarashi, Yasuhiko Itoh, Akira Shimizu, Tsutomu Igarashi, Kaoru Yoshizaki, Yoshitaka Fukunaga
Primary Sjögren's syndrome (SS) is a rare autoimmune disease, especially in children. Juvenile primary SS with interstitial nephritis is rare in Japan. We report on a 12-year-old girl in whom salivary gland swelling had recurred from the age of 5 years, SS was diagnosed at the age of 10 years, and interstitial nephritis developed at the age of 12 years. The patient presented with a chief complaint of swelling of both parotid glands. The patient had a history of recurrent parotitis from 5 years of age, with episodes recurring 5 to 6 times a year and resolving within 3 days each time...
2012: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
María E Dávila, Maritza Gil
OBJECTIVE: Determining oral manifestations and dental caries amongst children exposed to the immunodeficiency virus (HIV). METHODS: Thirty-seven (n=37) children attending the Colombian AIDS Control Program (PRONASIDA-Lara) pediatric service were studied. Parents and guardians were informed about the purpose of the study and its confidentiality. An oral examination was conducted by a dentist; parents/guardians were asked about their children's history of oral manifestations and this was corroborated with their clinical charts...
October 2011: Revista de Salud Pública
Sílvia Helena de Carvalho Sales-Peres, Marta Artemisa Abel Mapengo, Patrícia Garcia de Moura-Grec, Juliane Avansine Marsicano, André de Carvalho Sales-Peres, Arsenio Sales-Peres
The scope of this study was to identify the prevalence of oral manifestations in HIV+/AIDS patients at the DIA Pediatric Hospital of Maputo. All 90 patients were included in the research. Data on dental caries (dmft/DMFT index), soft tissues and saliva flow were analyzed. Information on diet and hygienic habits was obtained in a semi-structured questionnaire. The t- student and chi-square tests were used for statistical assessment. The most frequent oral lesion was candidiasis (5.5%) and upon further oral examination the prevalence of parotid enlargement was 23...
January 2012: Ciência & Saúde Coletiva
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