keyword
MENU ▼
Read by QxMD icon Read
search

Breast imaging

keyword
https://www.readbyqxmd.com/read/29451022/breast-tomosynthesis-for-the-clarification-of-mammographic-bi-rads-3-lesions-can-decrease-follow-up-examinations-and-enables-immediate-cancer-diagnosis
#1
Sonja D Bahrs, Vanessa Otto, Valerie Hattermann, Bernhard Klumpp, Markus Hahn, Konstantin Nikolaou, Katja Siegmann-Luz
Background The limited sensitivity of mammography in case of a high breast density often produces unclear or false-positive findings, so-called BI-RADS 3 lesions, which have to be followed up to prove benignity. Digital breast tomosynthesis (DBT) was developed to reduce such summation effects. Purpose To evaluate the influence of an additional DBT on the management of mammographic BI-RADS 3 findings and whether DBT can decrease the time to definitive diagnosis or not. Material and Methods We analyzed 87 patients with a mammographic non-calcified BI-RADS 3 lesion who underwent an additional DBT of the affected breast...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29450800/the-endogenous-subcellular-localisations-of-the-long-chain-fatty-acid-activating-enzymes-acsl3-and-acsl4-in-sarcoma-and-breast-cancer-cells
#2
Yassmeen Radif, Haarith Ndiaye, Vasiliki Kalantzi, Ruth Jacobs, Andrew Hall, Shane Minogue, Mark G Waugh
Fatty acid uptake and metabolism are often dysregulated in cancer cells. Fatty acid activation is a critical step that allows these biomolecules to enter cellular metabolic pathways such as mitochondrial β-oxidation for ATP generation or the lipogenic routes that generate bioactive lipids such as the inositol phospholipids. Fatty acid activation by the addition of coenzyme A is catalysed by a family of enzymes called the acyl CoA synthetase ligases (ACSL). Furthermore, enhanced expression of particular ACSL isoforms, such as ACSL4, is a feature of some more aggressive cancers and may contribute to the oncogenic phenotype...
February 15, 2018: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/29450753/use-of-breast-imaging-after-treatment-for-locoregional-breast-cancer-aft-01
#3
Taiwo Adesoye, Jessica R Schumacher, Heather B Neuman, Stephen Edge, Daniel McKellar, David P Winchester, Amanda B Francescatti, Caprice C Greenberg
BACKGROUND: Annual mammography is recommended after breast cancer treatment. However, studies suggest its under-utilization for Medicare patients. Utilization in the broader population is unknown, as is the role of breast magnetic resonance imaging (MRI). Understanding factors associated with imaging use is critical to improvement of adherence to recommendations. METHODS: A random sample of 9835 eligible patients receiving surgery for stages 2 and 3 breast cancer from 2006 to 2007 was selected from the National Cancer Database for primary data collection...
February 15, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29450505/in-shadow-and-light-images-of-transformation-through-breast-cancer
#4
Jennifer R Henneman
No abstract text is available yet for this article.
February 13, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29449780/tubular-adenoma-of-the-breast-a-clinicopathologic-study-of-a-series-of-9-cases
#5
Boubacar Efared, Ibrahim S Sidibé, Souley Abdoulaziz, Nawal Hammas, Laila Chbani, Hinde El Fatemi
Tubular adenoma of the breast is one of the most rare benign neoplasms, accounting for only 0.13% to 1.7% of all breast benign tumors. Little is known about this rare neoplasm as the current literature offers only some case reports or a few number of small series. The aim of our study is to provide some clinicopathologic features of the breast tubular adenoma. We retrospectively analyzed at our department of pathology all cases of breast tubular adenomas confirmed by immunohistochemistry over a period of 9 years (2009-2017)...
2018: Clinical Medicine Insights. Pathology
https://www.readbyqxmd.com/read/29448628/functionalized-magnetic-plga-nanospheres-for-targeting-and-bioimaging-of-breast-cancer
#6
Seung-Jun Lee, Hee-Jin Kim, Yong-Min Huh, Il Won Kim, Jae Hyun Jeong, Jin-Chul Kim, Jong-Duk Kim
Superparamagnetic iron oxide nanoparticles (SPIONs) are actively used as highly sensitive imaging probes to provide contrast in MRI. In this study, we propose the use of SPIONs encapsulated with antibody-conjugated poly(lactic-co-glycolic acid) (PLGA) as a potent theragnostic agent. The SPIONs were synthesized by a chemical co-precipitation method of ferric and ferrous ions, and subsequently encapsulated with PLGA by using an emulsification-diffusion method. Herceptin was chemically conjugated to the SPION-encapsulating PLGA nanoparticles to target the human epidermal growth factor receptor 2 (Her2/neu) overexpressing breast cancers...
March 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29446263/pulsed-terahertz-imaging-of-breast-cancer-in-freshly-excised-murine-tumors
#7
Tyler Bowman, Tanny Chavez, Kamrul Khan, Jingxian Wu, Avishek Chakraborty, Narasimhan Rajaram, Keith Bailey, Magda El-Shenawee
This paper investigates terahertz (THz) imaging and classification of freshly excised murine xenograft breast cancer tumors. These tumors are grown via injection of E0771 breast adenocarcinoma cells into the flank of mice maintained on high-fat diet. Within 1 h of excision, the tumor and adjacent tissues are imaged using a pulsed THz system in the reflection mode. The THz images are classified using a statistical Bayesian mixture model with unsupervised and supervised approaches. Correlation with digitized pathology images is conducted using classification images assigned by a modal class decision rule...
February 2018: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29446125/feasibility-of-high-spatiotemporal-resolution-for-an-abbreviated-3d-radial-breast-mri-protocol
#8
Jorge E Jimenez, Roberta M Strigel, Kevin M Johnson, Leah C Henze Bancroft, Scott B Reeder, Walter F Block
PURPOSE: To develop a volumetric imaging technique with 0.8-mm isotropic resolution and 10-s/volume rate to detect and analyze breast lesions in a bilateral, dynamic, contrast-enhanced MRI exam. METHODS: A local low-rank temporal reconstruction approach that also uses parallel imaging and spatial compressed sensing was designed to create rapid volumetric frame rates during a contrast-enhanced breast exam (vastly undersampled isotropic projection [VIPR] spatial compressed sensing with temporal local low-rank [STELLR])...
February 14, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29445216/evaluation-of-her2-specific-peptide-ligand-for-its-employment-as-radiolabeled-imaging-probe
#9
Hadis Honarvar, Enrica Calce, Nunzianna Doti, Emma Langella, Anna Orlova, Jos Buijs, Valentina D'Amato, Roberto Bianco, Michele Saviano, Vladimir Tolmachev, Stefania De Luca
HER2 transmembrane receptor is an important target in immunotherapy treatment of breast and gastroesophageal cancer. Molecular imaging of HER2 expression may provide essential prognostic and predictive information concerning disseminated cancer and aid in selection of an optimal therapy. Radiolabeled low molecular weight peptide ligands are particularly attractive as probes for molecular imaging, since they reach and bind to the target and clear from non-target organs and blood stream faster than bulky antibodies...
February 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29444034/label-free-cell-nuclear-imaging-by-gr%C3%A3-neisen-relaxation-photoacoustic-microscopy
#10
Xiaowei Liu, Terence T W Wong, Junhui Shi, Jun Ma, Qing Yang, Lihong V Wang
Photoacoustic microscopy (PAM) with ultraviolet (UV) laser illumination has recently been demonstrated as a promising tool that provides fast, label-free, and multilayered histologic imaging of human breast tissue. Thus far, the axial resolution has been determined ultrasonically. To enable optically defined axial resolution, we exploit the Grüneisen relaxation (GR) effect. By imaging mouse brain slices, we show that GRUV-PAM reveals detailed information about three-dimensional cell nuclear distributions and internal structures, which are important diagnostic features for cancers...
February 15, 2018: Optics Letters
https://www.readbyqxmd.com/read/29443834/does-2-stage-implant-based-breast-reconstruction-allow-for-a-larger-volume-of-the-definite-implant-compared-with-1-stage-reconstruction
#11
R C Killaars, J Hommes, R R van der Hulst, H J Tielemans, V L Negenborn, A Piatkowski
INTRODUCTION: Breast reconstruction using implants is still the main breast reconstruction technique worldwide. Current debate within implant-based breast reconstruction is whether to perform a 1-stage (direct implant) or 2-stage (tissue expander/implant) reconstruction. Volume differences between a woman's native breast and changes in volume after breast reconstruction might be an important factor for a patient's choice between these types of reconstruction. Three-dimensional imaging facilitates objective breast volume estimates...
February 13, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29440134/interobserver-variation-in-the-diagnosis-of-fibroepithelial-lesions-of-the-breast-a-multicentre-audit-by-digital-pathology
#12
Benjamin F Dessauvagie, Andrew H S Lee, Katie Meehan, Anju Nijhawan, Puay Hoon Tan, Jeremy Thomas, Bibiana Tie, Darren Treanor, Seemeen Umar, Andrew M Hanby, Rebecca Millican-Slater
AIM: Fibroepithelial lesions (FELs) of the breast span a morphological continuum including lesions where distinction between cellular fibroadenoma (FA) and benign phyllodes tumour (PT) is difficult. The distinction is clinically important with FAs managed conservatively while equivocal lesions and PTs are managed with surgery. We sought to audit core biopsy diagnoses of equivocal FELs by digital pathology and to investigate whether digital point counting is useful in clarifying FEL diagnoses...
February 13, 2018: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29439780/evolving-imaging-techniques-for-staging-axillary-lymph-nodes-in-breast-cancer
#13
REVIEW
S Lowes, A Leaver, K Cox, K Satchithananda, D Cosgrove, A Lim
The presence and extent of axillary nodal metastases at the time of breast cancer diagnosis is a critical factor in disease prognosis and plays a central role in deciding the best treatment for patients. Accurate assessment of the axilla is therefore an essential component in staging breast cancer. Over the years, axillary staging has evolved from surgical axillary lymph node dissection (ALND), with its numerous associated long-term complications, to the much less-radical surgical sentinel lymph node excision biopsy (SLNB), the current reference standard...
February 10, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29439777/special-issue-on-breast-imaging-part-1
#14
EDITORIAL
N Sharma
No abstract text is available yet for this article.
February 10, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29438745/an-automated-epifluorescence-microscopy-imaging-assay-for-the-identification-of-phospho-akt-level-modulators-in-breast-cancer-cells
#15
Elke Kaemmerer, Dane Turner, Amelia A Peters, Sarah J Roberts-Thomson, Gregory R Monteith
AKT is an enzyme of the PI3K/pAKT pathway, regulating proliferation and cell survival. High basal levels of active, phosphorylated AKT (pAKT) are associated with tumor progression and therapeutic resistance in some breast cancer subtypes, including HER2 positive breast cancers. Various stimuli can increase pAKT levels and elevated basal pAKT levels are a feature of PTEN-deficient breast cancer cell lines. The aim of this study was to develop an assay able to identify modulators of pAKT levels using an automated epifluorescence microscope and high content analysis...
February 10, 2018: Journal of Pharmacological and Toxicological Methods
https://www.readbyqxmd.com/read/29438007/best-practices-in-molecular-breast-imaging-a-guide-for-technologists
#16
Tiffinee Swanson, Thuy D Tran, Lacey Ellingson, Michael K O'Connor, Deborah J Rhodes, Katie N Hunt, Amy L Conners, Carrie B Hruska
Molecular breast imaging (MBI) technologists are required to possess a combination of nuclear medicine skills and mammographic positioning techniques. Currently, no formal programs offer this type of hybrid technologist training. The purpose of this perspective is to provide a best practices guide for technologists performing MBI. Familiarity with best practices may aid in obtaining high-quality MBI examinations by decreasing the likelihood of image artifacts, positioning problems and other factors that contribute to false negative or false positive findings...
February 2, 2018: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29437790/her3-mediated-resistance-to-hsp90-inhibition-detected-in-breast-cancer-xenografts-by-affibody-based-pet-imaging
#17
Carlos Daniel Martins, Chiara Da Pieve, Thomas A Burley, Rhodri Smith, Daniela M Ciobota, Louis Allott, Kevin Harrington, Wim J G Oyen, Graham Smith, Gabriela Kramer-Marek
PURPOSE: Recent studies have highlighted a role of human epidermal growth factor receptor 3 (HER3) in HER2-driven cancers (e.g. breast cancer) implicating the up-regulation of the receptor in resistance to HER-targeted therapies and Hsp90 inhibitors (e.g. AUY922). Therefore, we have developed an affibody-based PET radioconjugate that quantitatively assesses HER3 changes induced by Hsp90 inhibition in vivo Experimental Design: Z HER3:8698 affibody molecules were conjugated via the C-terminus cysteine to DFO-maleimide for 89 Zr radiolabeling...
February 6, 2018: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29437529/underutilization-of-supplemental-magnetic-resonance-imaging-screening-among-patients-at-high-breast-cancer-risk
#18
Stephanie Lee-Felker
No abstract text is available yet for this article.
February 13, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29435855/the-clinical-impact-of-molecular-breast-imaging-in-women-with-proven-invasive-breast-cancer-scheduled-for-breast-conserving-surgery
#19
Angela Collarino, Renato A Valdés Olmos, Lotta G A J van Berkel, Peter A Neijenhuis, Lidy M H Wijers, Frederik Smit, Lioe-Fee de Geus-Oei, Lenka M Pereira Arias-Bouda
PURPOSE: To investigate the clinical utility of molecular breast imaging (MBI) in patients with proven invasive breast cancer scheduled for breast-conserving surgery (BCS). METHODS: Following approval by the institutional review board and written informed consent, records of patients with newly diagnosed breast cancer scheduled for BCS who had undergone MBI for local staging in the period from March 2012 till December 2014 were retrospectively reviewed. RESULTS: A total of 287 women (aged 30-88 years) were evaluated...
February 13, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29435556/breast-biopsy-intensity-and-findings-following-breast-cancer-screening-in-women-with-and-without-a-personal-history-of-breast-cancer
#20
Diana S M Buist, Linn Abraham, Christoph I Lee, Janie M Lee, Constance Lehman, Ellen S O'Meara, Natasha K Stout, Louise M Henderson, Deirdre Hill, Karen J Wernli, Jennifer S Haas, Anna N A Tosteson, Karla Kerlikowske, Tracy Onega
Importance: There is little evidence on population-based harms and benefits of screening breast magnetic resonance imaging (MRI) in women with and without a personal history of breast cancer (PHBC). Objective: To evaluate biopsy rates and yield in the 90 days following screening (mammography vs magnetic resonance imaging with or without mammography) among women with and without a PHBC. Design, Setting, and Participants: Observational cohort study of 6 Breast Cancer Surveillance Consortium (BCSC) registries...
February 12, 2018: JAMA Internal Medicine
keyword
keyword
7239
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"