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Daniel S Orlovich, Jay B Brodsky, John G Brock-Utne
No abstract text is available yet for this article.
March 2018: Anesthesia and Analgesia
Ohlrich Marcus, Georg Royl
A hiccup is a reflex movement with diffusely distributed afferents and efferents in the thorax; its functional relevance is controversial. In its physiological form, it is mostly a minor complaint that stops spontaneously and rarely leads to medical consultation. However, prolonged agonizing hiccups represent serious deterioration of quality of life. Chronic hiccups by definition last for more than 48 h, with gastroesophageal reflux being the frequent underlying disease. Various other causes affect multiple organ systems, some with serious underlying diseases...
July 2017: Laryngo- Rhino- Otologie
Eva K Kohse, Markus W Hollmann, Hubert J Bardenheuer, Jens Kessler
Persistent singultus, hiccupping that lasts for longer than 48 hours, can have a tremendous impact on a patient's quality of life. Although involved neurologic structures have been identified, the function of hiccups remains unclear-they have been controversially interpreted as a primitive reflex preventing extent swallowing of amniotic fluid in utero, an archaic gill ventilation pattern, or a fetus' preparation for independent breathing. Persistent singultus often presents as a symptom for various diseases, most commonly illnesses of the central nervous system or gastrointestinal tract; they can also be evoked by a variety of pharmacological agents...
October 2017: Anesthesia and Analgesia
Sylvie Picker-Minh, Sebastian Hartenstein, Hans Proquitté, Sebastian Fröhler, Vera Raile, Nadine Kraemer, Sarah Apeshiotis, Michael Leipoldt, Karim D Kalache, Deborah Morris-Rosendahl, Eugen Boltshauser, Wei Chen, Angela M Kaindl
Pontine tegmental cap dysplasia is a rare hindbrain malformation syndrome with a hypoplastic pons, a tissue protrusion into the fourth ventricle, and cranial nerve dysfunction. We here report clinical, imaging, and genetic findings of the first extremely low-birth-weight preterm infant with pontine tegmental cap dysplasia born at 25 weeks of gestation and provide an overview of 29 sporadic cases. A prenatally diagnosed hypoplastic and rostrally shifted cerebellum was indicative of a hindbrain defect and later identified as an early sign of pontine tegmental cap dysplasia in our patient...
March 2017: Journal of Child Neurology
Jeffrey Gardecki, James Espinosa, Alan Lucerna, Jarrid Bernhardt
Hiccups (singultus) is often a benign, common and self- limited condition. A case of profound electrolyte disturbances presenting with chief complaint of hiccups is presented in which chlorpromazine was not administered and could have been problematic had it been given. For those who present to the ED with chief complaint of hiccups, it is critical to consider a life threatening etiology as the cause of their symptom. This case presents a potential pitfall in the management of singultus.
June 2017: American Journal of Emergency Medicine
Atsushi Saito, Toru Hatayama, Hiroyuki Kon, Taigen Nakamura, Tatsuya Sasaki
Intractable singultus due to cerebrovascular disease is very rare. We report a case of intractable singultus that improved after microvascular decompression and present a literature review. The patient was a 58-year-old man with a 30-year history of persistent singultus. Its frequency and duration gradually increased and it was resistant to multiple medical treatments. Microvascular decompression to relieve pressure on the anterolateral surface of the lower medulla oblongata from the vertebral artery resulted in the resolution of singultus...
October 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
David Arsanious, Spiro Khoury, Edgar Martinez, Ali Nawras, Gregory Filatoff, Hossam Ajabnoor, Umar Darr, Joseph Atallah
UNLABELLED: Hiccups are actions consisting of sudden contractions of the diaphragm and intercostals followed by a sudden inspiration and transient closure of the vocal cords. They are generally short lived and benign; however, in extreme and rare cases, such as esophageal carcinoma, they can become persistent or intractable, up to and involving significant pain, dramatically impacting the patient's quality of life. This case involves a 60-year-old man with a known history of squamous cell carcinoma of the esophagus...
May 2016: Pain Physician
Charles Amoatey Odonkor, Brittany Smith, Kimberly Rivera, Akhil Chhatre
Singultus are rare but notable adverse effect of epidural steroid injections (ESIs). To date, reports of persistent hiccups associated with ESIs have been reported mostly in adults aged 65 years or older. We present the first case of persistent hiccups in a septuagenarian who underwent repeated transforaminal ESIs for chronic lumbar radiculopathy. Under fluoroscopic guidance, 1.5 mL of 1% lidocaine (preservative free) and 0.8 mL of dexamethasone solution (10 mg/mL) was injected into the bilateral L4-L5 neural foramen and epidural space...
January 2017: American Journal of Physical Medicine & Rehabilitation
Christopher C Miller, Georg A Petroianu
During intrauterine life, hiccups are universally present, their incidence peaking in the third trimester. Alfons Mermann (1852-1908), a gynecologist from Mannheim, Germany, best known for having established the Luisenheim Woechnerinnenasyl [lying-in asylum] there in 1887, is viewed as the first physician to name and describe singultus foetalis [fetal hiccups] in a modern peer-reviewed scientific publication. This short report attempts to shed some light on the work of Dr. Mermann and to explore whether or not he was indeed the first to recognize this phenomenon...
October 2016: Journal of the History of the Neurosciences
M Steger, M Schneemann, M Fox
BACKGROUND: Hiccups are familiar to everyone, but remain poorly understood. Acute hiccups can often be terminated by physical manoeuvres. In contrast, persistent and intractable hiccups that continue for days or months are rare, but can be distressing and difficult to treat. AIM: To review the management of hiccups, including a systematic review of reported efficacy and safety of pharmacological treatments. METHODS: Available articles were identified using three electronic databases in addition to hand searching of published articles...
November 2015: Alimentary Pharmacology & Therapeutics
Nidhi Patel, Kevin O'Brien
The hiccup reflex arc involving the brainstem, phrenic and vagus nerves, and the sympathetic chain is associated with singultus. There are many possible organic, psychogenic, idiopathic, and iatrogenic instigators. We describe a case of singultus in a 69-year-old man secondary to his CPAP mask, with resolution after he stopped using the mask. Our case establishes that CPAP may be a cause of iatrogenic aerophagia leading to gastric distention, singultus, and emesis and highlights the importance of a complete history...
April 2015: ACG Case Reports Journal
Tadashi Nishikawa, Yoichiro Araki, Teruo Hayashi
Hiccups or singulata are rhythmic involuntary movements of the diaphragm, caused by a variety of conditions that interfere with the functions of the nerve nuclei in the medulla and supra-spinal hiccup center. Although neurotransmitters and receptors involved in the pathophysiology of hiccups are not defined well, dopamine has been considered to play an important role. In some cases, chlorpromazine or other antipsychotics are used for the treatment of intractable hiccups but their efficacy is often limited. This report involves an 18-year-old patient who experienced two episodes of intractable hiccups triggered by stress, which lasted for weeks or even months...
2015: Annals of General Psychiatry
Kristie Petree, Jonathan Bruner
Singultus, or hiccups, is a common medical condition. Despite exponential leaps in medicine, the pathophysiologic cause remains poorly defined. Persistent singultus has been associated with conditions such as pulmonary embolism and myocardial infarction. Singultus is also a well-known postoperative complication. The criterion standard of care for patients with singultus involves ruling out lethal pathologic causes, attempting physical stimulation with Valsava maneuvers or drinking water, and, if no relief has been achieved, administering drugs to ease the symptoms...
March 2015: Journal of the American Osteopathic Association
Benjamin Seidel, Gina Benaquista Desipio
Singultus, or hiccups, are involuntary spasms of the diaphragm that in most cases are harmless and self-limited. Treatments are reserved for those cases that persist, and current options include pharmacotherapeutics, complementary methods (such as acupuncture), and osteopathic manipulative treatment. A 32-year-old woman with stiff person syndrome and concurrent aminoacidopathy in the setting of acute inpatient rehabilitation was experiencing daily bouts of singultus, ranging from 20-minute to 5-hour durations...
August 2014: Journal of the American Osteopathic Association
V Sampath, Mahesh R Gowda, H R Vinay, S Preethi
Lateral medullary syndrome (LMS) is a constellation of varied neurologic manifestations seen in cerebrovascular accidents. The posterolateral part of the medulla oblongata of the brain stem and cerebellum receiving arterial blood supply from the posterior inferior cerebellar artery are the areas commonly affected. We present a case of a middle aged gentleman referred to our hospital for persistent intractable hiccups as presenting symptom of LMS. He presented to our emergency room with persistent hiccups and left sided cerebellar signs...
July 2014: Indian Journal of Psychological Medicine
Balasubramanyam Shankar, Ramakrishna Narayanan, Samir Mustaffa Paruthikunnan, Chaitanya Dattatray Kulkarni
No abstract text is available yet for this article.
2014: BMJ Case Reports
Georg A Petroianu
This short report attempts to shed light on the interesting but controversial personality of George T Dexter (ca1812 -?), the physician who first described manipulation of the female genitalia in a hysterical impressionable girl as being associated with the termination of singultus. Although his interaction with the young female patient would not meet today's ethical standards, his medical observation was valid and contributes to our understanding of the pathophysiology of singultus. He was well ahead of his colleagues who presented hiccup therapy case reports with similar or related pathophysiology mechanisms some 150 years later...
May 2016: Journal of Medical Biography
Mark E Peacock
Hiccups, or singulata (hiccup is singultus), are commonly experienced by most people at one time or another and are usually brief and self-limiting. Although pharmacotherapeutic agents are not generally considered causal in the etiology of hiccups, many clinicians empirically associate episodic hiccups in their patients as being drug induced. The two classes of drugs most often cited as causing hiccups are corticosteroids and benzodiazepines. This report involved a patient who was given preoperative dexamethasone and developed hiccups before anesthesia and surgery commenced...
2013: Case Reports in Dentistry
Georgi Maximov, Deepak Kamnasaran
BACKGROUND: Hiccup (Singultus) is a sudden and involuntary contraction of the diaphragm followed by a sharp closure of the epiglottis which results in the production of a specific "hic" sound. Normally, hiccups are treated without intervention. Intractable hiccups occur rarely but are a disturbing symptom underlying other health related disorders. CASE PRESENTATION: We report the clinical case of a 67-year-old male patient with myocardial infarction accompanied by intractable hiccups during the course of 8 months, and who was non-responsive to chlorpromazine or metoclopramide, and baclofen; drugs routinely used to treat this condition...
2013: BMC Research Notes
Georg A Petroianu
Sir William Osler (1849-1919) is associated with a long list of contributions and eponymous entities including filaria, maneuvers, nodules, syndromes, and triads. Among the less known ones is the Oslerian pulling of the tongue for termination of obstinate hiccup (singultus). Janet Travell (1901-1977) , physician to two United States presidents, attributed the tongue-pulling maneuver to Osler. Dr. Travell cites Osler's Principles and Practice of Medicine from 1912, where mention of the remedy can be found. The therapy, however, is much older and (perhaps not surprisingly) of French origin...
2013: Journal of the History of the Neurosciences
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