Giorgio Ivan Russo, Ramadan Saleh, Federica Finocchi, Almas Ramadhani Juma, Damayanthi Durairajanayagam, Oguzhan Kahraman, Emrullah Söğütdelen, Ioannis Sokolakis, Ranjit B Vishwakarma, Fahmi Bahar, Ahmed M Harraz, Parviz Kavoussi, Widi Atmoko, Eric Chung, Naveen Kumar, Wael Zohdy, Amarnath Rambhatla, Mohamed Arafa, Nguyen Ho Vinh Phuoc, Gianmaria Salvio, Aldo E Calogero, Tuncay Toprak, Germar-Michael Pinggera, Rossella Cannarella, Giovanni Colpi, Taha Abo-Almagd Abdel-Meguid Hamoda, Rupin Shah, Ashok Agarwal
PURPOSE: Varicocele has been associated with high seminal oxidative stress (OS), impaired semen quality, and reduced male fertility potential. However, the exact mechanism(s) underlying the development of varicocele-mediated infertility and the cause-effect relationship between varicocele and testicular dysfunction are not fully understood. The aim of this systematic review and meta-analysis (SRMA) is to investigate the impact of varicocele on testicular OS markers and sperm parameters in experimental animals with varicocele as compared to animals without varicocele...
February 7, 2024: World Journal of Men's Health