Claire Basille, René Frydman, Abdelwahab El Aly, Laetitia Hesters, Renato Fanchin, Gérard Tachdjian, Julie Steffann, Marc LeLorc'h, Nelly Achour-Frydman
Preimplantation genetic diagnosis (PGD) is used to analyze embryos genetically before their transfer into the uterus. It was developed first in England in 1990, as part of progress in reproductive medicine, genetic and molecular biology. PGD offers couples at risk the chance to have an unaffected child, without facing termination of pregnancy. Embryos are obtained by in vitro fertilization with intracytoplasmic sperm injection (ICSI), and are biopsied mostly on day 3; blastocyst biopsy is mentioned as a possible alternative...
July 2009: European Journal of Obstetrics, Gynecology, and Reproductive Biology