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https://www.readbyqxmd.com/read/27892720/association-between-chronic-pancreatitis-and-pyogenic-liver-abscess-a-nationwide-population-study
#1
Chih-Wei Tseng, Yu-Tso Chen, Cheng-Li Lin, Ji-An Liang
BACKGROUND: The relationship between chronic pancreatitis (CP) and subsequent pyogenic liver abscess (PLA) is not well understood. METHODS: We investigated the risk of PLA in patients with CP using inpatient claims data from the Taiwan National Health Insurance Program for the period 2000-2010, we identified 17,810 patients with chronic pancreatitis (CP group) and 71,240 patients without CP (non-CP group). Both cohorts were followed until a diagnosis of PLA, until they were censored from the study because of loss to follow-up, death, or termination of insurance, or until the study cut-off date of December 31, 2011...
November 28, 2016: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/27876450/intraductal-papillary-neoplasm-of-the-bile-duct-a-case-report
#2
Karen Peeters, Peter Delvaux, Frederik Huysentruyt
Intraductal papillary neoplasm of the bile duct (IPNB) is a rare variant of bile duct tumors, characterized by papillary growth within the bile duct lumen and is regarded as a biliary counterpart of intraductal papillary mucinous neoplasm (IPMN) of the pancreas. IPNBs are mainly found in patients from Far Eastern areas, where hepatolithiasis and clonorchiasis are endemic. The Western experience, however, remains limited. In this article, we report a 56-year-old man, referred to our hospital because of deranged liver function tests...
November 23, 2016: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/27812075/can-a-diabetic-foot-be-malignant
#3
Muhammad Shoaib Zaidi, Asim Hassan, Samir Ouizi
Diabetes has been linked with malignancies like colon, rectum, liver, biliary tract, pancreas, kidney, leukaemia and melanoma. Melanoma can sometimes manifest as a diabetic foot ulcer.We describe an elderly male with Type 2 diabetes, who had presented to us with a non-healing wound at the right heel, that later turned out to be an invasive malignant melanoma.
November 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27766198/igg4-related-lung-disease-extending-to-the-thoracic-vertebrae
#4
Alexandros Stamatopoulos, Davide Patrini, Efstratios Koletsis, Elaine Borg, Reena Khiroya, Martin Hayward, David Lawrence, Nikolaos Panagiotopoulos
IgG4-related disease (IgG4-RD) is a fibroinflammatory condition that can affect practically every organ. Although it was first identified in pancreas and salivary glands, major organs like liver, biliary tree, kidney, thyroid glands and lungs are commonly involved, sometimes resulting in organ failure. We describe a case of an 41-year-old man presented with back pain after a rotator cuff injury. A Computed Tomography (CT) revealed incidentally a right lower lobe paravertebral lesion extending across the T5 and T6 vertebral levels and invading into the adjacent pleural surface...
2016: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/27756258/development-of-oxy111a-a-novel-hypoxia-modifier-as-a-potential-antitumor-agent-in-patients-with-hepato-pancreato-biliary-neoplasms-protocol-of-a-first-ib-iia-clinical-trial
#5
Perparim Limani, Michael Linecker, Philipp Kron, Panagiotis Samaras, Bernhard Pestalozzi, Roger Stupp, Alexander Jetter, Philipp Dutkowski, Beat Müllhaupt, Andrea Schlegel, Claude Nicolau, Jean-Marie Lehn, Henrik Petrowsky, Bostjan Humar, Rolf Graf, Pierre-Alain Clavien
BACKGROUND: Solid tumors, such as hepato-pancreato-biliary cancer, develop tumor hypoxia with tumor growth. Despite advances in surgery, a majority of these patients are in an unresectable condition. At this stage standard cytotoxic chemotherapy regimens are applied with limited success. Novel biological treatment options based on an antiangiogenic mechanism of action neglect other hypoxia mediated mechanisms (e.g. epithelial-mesenchymal transition, Warburg effect, and immunological response) leading to an increased invasiveness with a poor outcome...
October 19, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27673548/nonmucinous-biliary-epithelium-is-a-frequent-finding-and-is-often-the-predominant-epithelial-type-in-mucinous-cystic-neoplasms-of-the-pancreas-and-liver
#6
Kristen Zhelnin, Yue Xue, Brian Quigley, Michelle D Reid, Hyejeong Choi, Bahar Memis, Volkan Adsay, Alyssa M Krasinskas
Mucinous cystic neoplasms (MCNs) can occur in the pancreas and liver. Classically, these cystic lesions are lined by columnar mucinous epithelium with underlying ovarian-type stroma. It has been proposed that cysts with ovarian-type stroma and nonmucinous epithelium be considered separate entities in both the pancreas and liver. Using a series of 104 pancreatic and 32 hepatic cases, we aimed to further characterize the epithelium present in MCNs. Mucinous epithelium was defined as pancreatic intraepithelial neoplasia-like columnar cells with pale pink/clear apical mucin...
September 26, 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27660206/intrahepatic-biliary-duct-branching-patterns-cystic-duct-anomalies-and-pancreas-divisum-in-a-tertiary-referral-center-a-magnetic-resonance-cholangiopancreaticographic-study
#7
Ankur Gupta, Praveer Rai, Vivek Singh, Rakesh Kumar Gupta, Vivek Anand Saraswat
BACKGROUND: Knowledge about anatomic variations in intrahepatic biliary ducts (IHBD) is relevant for performing biliary drainage and for avoiding bile duct injury during cholecystectomy and liver resections. Low insertion of cystic duct (LICD) is a common anatomic variant. Pancreas divisum is the commonest congenital anomaly of pancreas; it has been causally linked with recurrent acute pancreatitis (RAP). METHODS: Magnetic resonance cholangiopancreaticography (MRCP) images of 500 consecutive patients were reviewed for anatomic variants of IHBD, cystic duct, and pancreatic duct...
September 2016: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/27622194/autoimmune-pancreatitis-and-igg4-related-disease-in-three-children
#8
Rishi Bolia, Sze Yee Chong, Lee Coleman, Duncan MacGregor, Winita Hardikar, Mark R Oliver
We report 3 children who presented with fever and abdominal pain, deranged liver function tests, and on abdominal ultrasound were found to have an enlarged pancreas, substantial abdominal lymphadenopathy, and extrahepatic biliary duct dilatation. After ruling out malignancy, probable immunoglobulin G4-related disease (IgG4RD) associated with autoimmune pancreatitis was considered. This condition was first described in the adults and often mimics pancreatic cancer. It can involve multiple organs, either synchronously or metachronously, and is rarely reported in children...
July 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/27607171/high-uptake-of-fdg-along-a-biliary-stent
#9
Yasunari Nagasaki, Hiromichi Yamane, Nobuaki Ochi, Yoshihiro Honda, Nagio Takigawa
A 66-year-old woman presented with abdominal discomfort. Contrast-enhanced CT revealed a mass in the pancreas and multiple liver metastases. Pathological examination confirmed the mass to be primary pancreatic cancer. Endoscopic insertion of a biliary stent was performed to prevent common bile duct obstruction. Subsequently, she received combination chemotherapy, which resulted in a complete response. FDG-PET-CT after chemotherapy revealed a high uptake of FDG along the outline of the biliary stent, with complete disappearance of both the primary and metastatic tumors...
November 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27522720/-prospects-for-clinical-application-of-statins-in-gastroenterology
#10
REVIEW
A A Svistunov, M A Osadchuk, N V Kireeva
We present the analytical review of non-cardial effects of statins used in gastroenterology with the data illustrating their high antibacterial activity as exemplified by combined therapy of conditions associated with Helicobacter pylori infection. Special emphasis is laid on anti-inflammatory and oncoprotective mechanisms of statin action that are successfully made use of for the treatment of liver, pancreas, gallbladder, and biliary system diseases. Prophylactic aspects of statin application to overcome an addiction to fast food are discussed...
2016: Klinicheskaia Meditsina
https://www.readbyqxmd.com/read/27513696/normograms-for-the-extrahepatic-bile-duct-diameter-in-children
#11
Albert Feng, Sara M O'hara, Resmi Gupta, Lin Fei, Tom K Lin
OBJECTIVE: The normal diameter of the extrahepatic bile duct (EHD) in children has been poorly studied. Prior studies have enrolled small subject numbers, have studied only specific pediatric age groups or have potential bias due to loosely defined exclusion criteria. We sought to establish parameters for the normal diameter of the EHD in children from birth to late adolescence, including premature infants. METHODS: A 12½ month IRB-approved, HIPAA-compliant, retrospective chart review of all transabdominal ultrasounds performed on children (<18 years old) was conducted at a single pediatric tertiary referral center...
August 10, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27510673/severe-liver-dysfunction-in-an-infant-with-cystic-fibrosis-masquerading-as-metabolic-liver-disease
#12
K P Srikanth, Inusha Panigrahi, Babu Ram Thapa, Kim Vaiphei
We present a rare presentation of cystic fibrosis with neonatal cholestasis. Histological features of mucoviscidosis were present in liver involving the biliary tract, intestinal mucosa, pancreas, and lung. Besides, there was a rare association with autosomal dominant type of polycystic renal disease.
July 2016: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/27485065/trends-in-the-scientific-program-of-the-americas-hepato-pancreato-biliary-association-ahpba-annual-meeting-over-the-past-decade-the-more-things-change-the-more-they-stay-the-same
#13
Chad G Ball, Elijah Dixon, Charles M Vollmer
BACKGROUND: Numerous clinical and basic science innovations have been presented at the AHPBA. The objective was to define changes in content and methodology of the scientific program over the past decade. METHODS: AHPBA abstracts from the past 10-years were reviewed by 2 investigators (volume, content, origin, methodology). RESULTS: Of 2194 total AHPBA abstracts (2005-2015), the volume per year decreased over time (2005 = 283; 2015 = 177; p < 0...
August 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/27376210/resection-reconstruction-of-aberrant-right-hepatic-artery-during-whipple-procedure-pancreaticoduodenectomy
#14
Raza Sayyed, Iffat Rehman, Imran Khalid Niazi, Muhammed Aasim Yusuf, Aamir Ali Syed, Faisal V
Aberrant hepatic arterial anatomy poses a challenge for the surgeon during Whipple procedure. Intraoperative injury to the aberrant vasculature results in hemorrhagic or ischemic complications involving the liver and biliary tree. We report a case of replaced right hepatic artery arising from the superior mesenteric artery in a patient with periampullary carcinoma of the pancreas, undergoing pancreaticoduodenectomy. The aberrant artery was found to be coursing through the pancreatic parenchyma. This is a rare vascular anomaly...
June 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27342825/the-multidisciplinary-approach-to-gi-cancer-results-in-change-of-diagnosis-and-management-of-patients-multidisciplinary-care-impacts-diagnosis-and-management-of-patients
#15
Cheryl Meguid, Richard D Schulick, Tracey E Schefter, Christopher H Lieu, Megan Boniface, Nicole Williams, Jon D Vogel, Csaba Gajdos, Martin McCarter, Barish H Edil
BACKGROUND: The multidisciplinary approach to GI cancer is becoming more widespread as a result of multimodality therapy. At the University of Colorado Hospital (UCH), we utilize a formal multidisciplinary approach through specialized clinics across a variety of settings, including pancreas and biliary cancer, esophageal and gastric cancer, liver cancer and neuroendocrine tumors (NET), and colorectal cancer. Patients with these suspected diagnoses are seen in a multidisciplinary clinic...
June 24, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27327560/combined-resection-of-aberrant-right-hepatic-artery-without-anastomosis-in-panceaticoduodenectomy-for-pancreatic-head-cancer-a-case-report
#16
Atsushi Nanashima, Naoya Imamura, Yuki Tsuchimochi, Masahide Hiyoshi, Yoshiro Fujii
INTRODUCTION: This case report is intended to inform pancreas surgeons of our experience in operative management of aberrant pancreatic artery. PRESENTATION OF CASE: A 63-year-old woman was admitted to our institute's Department of Surgery with obstructive jaundice, and the pancreas head tumor was found. To improve liver dysfunction, an endoscopic retrograde nasogastric biliary drainage tube was placed in the bile duct. Endoscopic fine-needle aspiration showed a pancreas head carcinoma invading the common bile duct, the aberrant right hepatic artery arising from the superior mesenteric artery, and the portal vein...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27261244/creating-an-animation-enhanced-video-library-of-hepato-pancreato-biliary-and-transplantation-surgical-procedures
#17
Albert Fung, Paul Kelly, Gordon Tait, Paul D Greig, Ian D McGilvray
The potential for integrating real-time surgical video and state-of-the art animation techniques has not been widely applied to surgical education. This paper describes the use of new technology for creating videos of liver, pancreas and transplant surgery, annotating them with 3D animations, resulting in a freely-accessible online resource: The Toronto Video Atlas of Liver, Pancreas and Transplant Surgery ( http://tvasurg.ca ). The atlas complements the teaching provided to trainees in the operating room, and the techniques described in this study can be readily adapted by other surgical training programmes...
January 2016: Journal of Visual Communication in Medicine
https://www.readbyqxmd.com/read/27181554/overlap-of-igg4-related-disease-and-primary-biliary-cirrhosis-complicated-with-autoimmune-thrombocytopenia
#18
Mika Takasumi, Masayuki Miyata, Masahito Kuroda, Kumiko Terashima, Kazumichi Abe, Atsushi Takahashi, Hiroko Kobayashi, Kazuhiro Tazaki, Hiroshi Watanabe, Hiromasa Ohira
A 63-year-old woman was referred to Fukushima Red Cross Hospital with an enlargement of the left submandibular gland and subcutaneous bleeding in the chest and legs. A diffuse enlargement of the pancreas was also detected by abdominal computed tomography, and laboratory data showed severe thrombocytopenia. She was diagnosed with IgG4-related disease (IgG4-RD) complicated with autoimmune thrombocytopenia and was treated with methylprednisolone, after which the number of platelets favorably increased. Further investigation for liver dysfunction revealed underlying primary biliary cirrhosis (PBC)...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27180936/serum-bilirubin-levels-are-positively-associated-with-glycemic-variability-in-women-with-type-2-diabetes
#19
Lee Kyung Kim, Eun Roh, Min Joo Kim, Min Kyeong Kim, Kyeong Seon Park, Soo Heon Kwak, Young Min Cho, Kyong Soo Park, Hak Chul Jang, Hye Seung Jung
AIMS/INTRODUCTION: Glycemic variability is known to induce oxidative stress. We investigate relationships between glycemic variability and serum bilirubin levels, an endogenous antioxidant, in patients with diabetes. MATERIALS AND METHODS: A cross sectional study was conducted with 77 patients with type 2 diabetes who had been recruited to 2 clinical studies from 2008 to 2014. There were no participants with diseases of pancreas, liver, biliary tract, and chronic renal insufficiency...
April 2, 2016: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/27166199/ciliated-foregut-cyst-of-the-common-hepatic-duct-an-unusual-mimic-of-a-type-ii-choledochal-cyst
#20
Jonathan Cottreau, Andreu Costa, Mark Walsh, Thomas Arnason
Ciliated foregut cysts typically arise in the liver and pancreas, with rare cases reported to arise in the gallbladder wall. Herein, we describe an unusual case of a patient with a ciliated foregut cyst arising from the wall of the common hepatic duct, which has not been reported previously. As a result of its unique anatomical location, the cyst was mistaken for a type II choledochal cyst on preoperative imaging. The cyst caused intermittent biliary obstruction that resolved following surgical resection.
October 2016: International Journal of Surgical Pathology
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