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https://www.readbyqxmd.com/read/29054589/baseline-asthma-burden-comorbidities-and-biomarkers-in-omalizumab-treated-patients-in-prospero
#1
Bradley E Chipps, Robert S Zeiger, Allan T Luskin, William W Busse, Benjamin L Trzaskoma, Evgeniya N Antonova, Hooman Pazwash, Susan L Limb, Paul G Solari, Noelle M Griffin, Thomas B Casale
BACKGROUND: Patients included in clinical trials do not necessarily reflect the real-world population. OBJECTIVE: To understand the characteristics, including disease and comorbidity burden, of patients with asthma receiving omalizumab in a real-world setting. METHODS: The Prospective Observational Study to Evaluate Predictors of Clinical Effectiveness in Response to Omalizumab (PROSPERO) was a US-based, multicenter, single-arm, and prospective study...
October 17, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29053179/providing-family-planning-services-at-primary-care-organizations-after-the-exclusion-of-planned-parenthood-from-publicly-funded-programs-in-texas-early-qualitative-evidence
#2
Kari White, Kristine Hopkins, Daniel Grossman, Joseph E Potter
OBJECTIVE: To explore organizations' experiences providing family planning during the first year of an expanded primary care program in Texas. DATA SOURCES: Between November 2014 and February 2015, in-depth interviews were conducted with program administrators at 30 organizations: 7 women's health organizations, 13 established primary care contractors (e.g., community health centers, public health departments), and 10 new primary care contractors. STUDY DESIGN: Interviews addressed organizational capacities to expand family planning and integrate services with primary care...
October 20, 2017: Health Services Research
https://www.readbyqxmd.com/read/29052956/meta-analysis-of-full-roc-curves-using-bivariate-time-to-event-models-for-interval-censored-data
#3
Annika Hoyer, Stefan Hirt, Oliver Kuss
Systematic reviews and meta-analyses are the cornerstones of evidence based medicine and inform treatment, diagnosis, or prevention of individual patients as well as policy decisions in health care. Statistical methods for the meta-analysis of intervention studies are well established today. Meta-analysis for diagnostic accuracy trials has also been a vivid research area in recent years which is especially due to the increased complexity of their bivariate outcome of sensitivity and specificity. The situation is even more challenging when single studies report a full ROC curve with several pairs of sensitivity and specificity, each pair for a different threshold...
October 20, 2017: Research Synthesis Methods
https://www.readbyqxmd.com/read/29052947/exploring-opportunities-to-support-mental-health-care-using-social-media-a-survey-of-social-media-users-with-mental-illness
#4
John A Naslund, Kelly A Aschbrenner, Gregory J McHugo, Jürgen Unützer, Lisa A Marsch, Stephen J Bartels
AIM: Social media holds promise for expanding the reach of mental health services, especially for young people who frequently use these popular platforms. We surveyed social media users who self-identified as having a mental illness to learn about their use of social media for mental health and to identify opportunities to augment existing mental health services. METHODS: We asked 240 Twitter users who self-identified in their profile as having a mental illness to participate in an online survey...
October 20, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29052663/self-management-intervention-for-adult-cancer-survivors-after-treatment-a-systematic-review-and-meta-analysis
#5
Soo Hyun Kim, Kisook Kim, Deborah K Mayer
PROBLEM IDENTIFICATION: This study aims to evaluate the effects of self-management interventions (SMIs) for cancer survivors who completed primary treatment. 
. LITERATURE SEARCH: Using PubMed, EMBASE, CINAHL®, PsycINFO®, and Cochrane Central Register of Controlled Trails (CENTRAL), the authors conducted a systematic search of randomized, controlled trials published in English from database conception through June 2016. 
. DATA EVALUATION: The meta-analysis was conducted with Cochrane Review Manager, version 5...
November 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/29052163/the-use-of-health-state-utility-values-in-decision-models
#6
REVIEW
Roberta Ara, John Brazier, Ismail Azzabi Zouraq
Methodological issues of how to use health state utility values (HSUVs) in decision models arise frequently, including the most appropriate evidence to use as the baseline (e.g. the baseline HSUVs associated with avoiding a particular health condition or event), how to capture changes due to adverse events and how to appropriately capture uncertainty in progressive conditions where the expected change in quality of life is likely to be monotonically decreasing over time. As preference-based measures provide different values when collected from the same patient, it is important to ensure that all HSUVs used within a single model are obtained from the same instrument where ever possible...
October 19, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/29049920/factors-associated-with-vision-related-quality-of-life-among-the-adult-population-living-in-nagorno-karabagh
#7
T Harutyunyan, A Giloyan, V Petrosyan
OBJECTIVES: Visual impairment and blindness are major public health problems causing significant suffering, disability, loss of productivity, and diminishing quality of life for millions of people. This study explored the factors associated with the overall vision-related quality of life (VRQoL) and its different domains in the adult population of Nagorno Karabakh and assessed the independent contribution of specific eye diseases to VRQoL. STUDY DESIGN: A cross-sectional study...
October 16, 2017: Public Health
https://www.readbyqxmd.com/read/29049019/mammography-use-in-portugal-national-health-survey-2014
#8
Sofia Chkotua, Bárbara Peleteiro
INTRODUCTION: Understanding the patterns of mammography use and monitoring changes in use are essential to improving national health policy for breast cancer control. We aimed to describe the use of mammography in Portugal and to identify the determinants of its nonuse and underuse by examining data from the National Health Survey 2014. METHODS: We analyzed data on 8,758 women aged 30 years or older. We defined women at an eligible age for mammography as women aged 45 to 69...
October 19, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/29046193/health-related-quality-of-life-in-danish-children-with-hereditary-angioedema
#9
Anne Aabom, Dan Nguyen, Niels Fisker, Anette Bygum
BACKGROUND: The potentially life-threatening disease hereditary angioedema with C1-inhibitor deficiency (C1-INH-HAE) can have considerable impact on the health-related quality of life (HRQoL) in adult patients. Half the patients with C1-INH-HAE develop symptoms before the age of 10 years. However, the HRQoL in children with C1-INH-HAE is almost unexplored. OBJECTIVE: To investigate HRQoL in Danish children with C1-INH-HAE, including possible correlations to disease severity and attack frequency...
November 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/29045938/effectiveness-of-nivolumab-versus-docetaxel-as-second-line-treatment-in-non-small-cell-lung-cancer-patients-in-clinical-practice
#10
Pablo Calpe-Armero, Rafael Ferriols-Lisart, Francisco Ferriols-Lisart, Alejandro Pérez-Pitarch
AIMS: To evaluate the effectiveness of nivolumab as second-line treatment compared to standard therapy with docetaxel in adult patients with non-small cell lung cancer (NSCLC) in clinical practice. METHODS: This is an observational, retrospective cohort study of adult patients diagnosed with NSCLC, stage III-IV, treated with docetaxel or nivolumab as second-line treatment. The end points evaluated were overall survival (OS) and progression-free survival (PFS). PFS and OS were described using the Kaplan-Meier method...
October 19, 2017: Chemotherapy
https://www.readbyqxmd.com/read/29045260/encopresis-plus
#11
DePorres Cormier, Marie Reilly, Amy Young, Marilyn Augustyn
Dexter is a 12-year-old boy who presents with his maternal grandmother for follow-up to primary care for secondary encopresis. Dexter presented, 18 months ago, with a 3-month history of secondary encopresis. At that time, a comprehensive assessment revealed functional constipation resulting in encopresis. Dexter's symptoms resolved with a combination of medication management and behavioral strategies; laxatives were discontinued 12 months ago.Dexter's grandmother reports that for the past 6 months, her grandson developed encopresis once again...
October 17, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29041818/a-content-analysis-of-peripheral-arterial-disease-patient-reported-outcome-measures-using-the-international-classification-of-functioning-disability-and-health
#12
Candice Lee Osborne, David Seth Kauvar
BACKGROUND: The purpose of this study was to link, classify and describe the content of peripheral arterial disease (PAD)-specific patient-reported outcome measures using the International Classification of Functioning. The results were then analyzed to determine if these assessments provide clinicians and researchers with a comprehensive understanding of the lived experience of patients with PAD. METHODS: Each meaningful concept in identified PAD assessments was linked to the International Classification of Functioning, Disability and Health to determine included and excluded content areas...
October 17, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29040469/the-commercialization-of-traditional-medicine-in-modern-cambodia
#13
Bandeth Ros, Gillian Lê, Barbara McPake, Suzanne Fustukian
Globally, traditional medicine has long been used to address relatively common illness, mental ill health and during childbirth and post-natal care. However, traditional medicine is primarily provided by the private sector and it is unclear how far expenditures on traditional medicine contribute to household impoverishment. A life history method was used to understand the health seeking experience of 24 households over the last 60 years in Cambodia, a country with high out-of-pocket expenditures for health...
October 11, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/29039376/decision-support-systems-in-health-care-velocity-of-apriori-algorithm
#14
Mario Somek, Mira Hercigonja-Szekeres
The amount of stored data in health information systems can reach tera- and petabytes and application of specific algorithms in the field of data mining makes finding useful information suitable for making quality business decisions. A frequently used method for determining the rules of the relationship between attributes is the Association rule by applying Apriori algorithm. Lack of basic Apriori algorithm is derived from the slow work due to multiple scanned data sets. By examining the speed of generating the basic rules in relation to the improved Apriori algorithm by using software RapidMiner confirmed that the time required to generate rules for Improved algorithm is shorter, the rules are quickly generated particularly for large data sets, which is an advantage for making decisions...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29039053/health-care-institutions-volume-is-significantly-associated-with-postoperative-outcomes-in-bariatric-surgery
#15
Laurent Brunaud, Stephanie Polazzi, Jean-Christophe Lifante, Lea Pascal, David Nocca, Antoine Duclos
PURPOSE: The volume of bariatric surgery has significantly increased over the past decade with concomitant postoperative outcomes improvement. The goal of this nationwide study was to estimate the volume-outcome relationship in bariatric surgery at the hospital level. MATERIALS AND METHODS: A cross-sectional analysis of all patients who underwent bariatric surgery procedure in France from January 2011 to December 2014 was designed. Volume-outcome relationship was analyzed using generalized estimating equations...
October 16, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29038094/transdiagnostic-psychodynamic-web-based-self-help-intervention-following-inpatient-psychotherapy-results-of-a-feasibility-study-and-randomized-controlled-trial
#16
Rüdiger Zwerenz, Jan Becker, Robert Johansson, Ronald J Frederick, Gerhard Andersson, Manfred E Beutel
BACKGROUND: Mental disorders have become a major health issue, and a substantial number of afflicted individuals do not get appropriate treatment. Web-based interventions are promising supplementary tools for improving health care for patients with mental disorders, as they can be delivered at low costs and used independently of time and location. Although psychodynamic treatments are used frequently in the face-to-face setting, there has been a paucity of studies on psychodynamic Web-based self-help interventions...
October 16, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/29035965/effectiveness-of-bedrails-in-preventing-falls-among-hospitalized-older-adults-a-systematic-review
#17
Paulo Marques, Carmen Queirós, João Apóstolo, Daniela Cardoso
BACKGROUND: Falls are a major problem today affecting adults of any age, but the elderly are a population that is more susceptible to falls. Falls are the leading cause of injury or death among older adults. Hospitalized older people are particularly vulnerable to falls. Falls cause direct injuries (minor injuries, severe wounds of the soft tissues and bone fractures) to patients and increased length of stay. The prevention of falls is commonly considered an indicator of the quality of care...
October 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29035706/serious-suicide-attempts-in-outpatients-with-multiple-substance-use-disorders
#18
R Icick, E Karsinti, J-P Lépine, V Bloch, G Brousse, F Bellivier, F Vorspan
BACKGROUND: Suicide is a major public health concern and suicide attempts (SA) are frequent and burdensome in people suffering from substance use disorders (SUDs). In particular, serious SAs are a preoccupying form of attempt, which remain largely overlooked in these populations, especially regarding basic risk factors such as gender, addictive comorbidity and substance use patterns. Thus, we undertook a gender-specific approach to identify the risk factors for serious SAs in outpatients with multiple SUDs...
September 23, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29035611/are-people-who-inject-drugs-frequent-users-of-emergency-department-services-a-cohort-study-2008-2013
#19
Dhanya Nambiar, Tim Spelman, Mark Stoové, Paul Dietze
BACKGROUND: Although people who inject drugs (PWID) have been described as frequent users of emergency services, the majority of research is cross-sectional and involves records from a single emergency department (ED). OBJECTIVES: We describe characteristics of state-wide ED presentations in a cohort of PWID, and compare presentation rates to the general population. We also examine characteristics associated with frequent ED use. METHODS: We used data from a retrospective linkage of public ED presentations from a cohort of 678 PWID between January 2008 and June 2013...
October 16, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/29034538/association-of-insomnia-severity-with-well-being-quality-of-life-and-health-care-costs-a-cross-sectional-study-in-older-adults-with-chronic-pain-pains65
#20
E Dragioti, L Bernfort, B Larsson, B Gerdle, L Å Levin
BACKGROUND: Insomnia is one of the most common complaints in chronic pain. This study aimed to evaluate the association of insomnia with well-being, quality of life and health care costs. METHODS: The sample included 2790 older individuals (median age = 76; interquartile range [IQR] = 70-82) with chronic pain. The participants completed a postal survey assessing basic demographic data, pain intensity and frequency, height, weight, comorbidities, general well-being, quality of life and the insomnia severity index (ISI)...
October 16, 2017: European Journal of Pain: EJP
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