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https://www.readbyqxmd.com/read/28810999/case-report-on-the-use-of-a-custom-myoelectric-elbow-wrist-hand-orthosis-for-the-remediation-of-upper-extremity-paresis-and-loss-of-function-in-chronic-stroke
#1
Stefanie Dunaway, D Brianna Dezsi, Jessica Perkins, Daniel Tran, Jonathan Naft
INTRODUCTION: This case study describes the application of a commercially available, custom myoelectric elbow-wrist-hand orthosis (MEWHO), on a veteran diagnosed with chronic stroke with residual left hemiparesis. The MEWHO provides powered active assistance for elbow flexion/extension and 3 jaw chuck grip. It is a noninvasive orthosis that is driven by the user's electromyographic signal. Experience with the MEWHO and associated outcomes are reported. MATERIALS AND METHODS: The participant completed 21 outpatient occupational therapy sessions that incorporated the use of a custom MEWHO without grasp capability into traditional occupational therapy interventions...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28806817/the-effects-of-cannabis-among-adults-with-chronic-pain-and-an-overview-of-general-harms-a-systematic-review
#2
Shannon M Nugent, Benjamin J Morasco, Maya E O'Neil, Michele Freeman, Allison Low, Karli Kondo, Camille Elven, Bernadette Zakher, Makalapua Motu'apuaka, Robin Paynter, Devan Kansagara
Background: Cannabis is increasingly available for the treatment of chronic pain, yet its efficacy remains uncertain. Purpose: To review the benefits of plant-based cannabis preparations for treating chronic pain in adults and the harms of cannabis use in chronic pain and general adult populations. Data Sources: MEDLINE, Cochrane Database of Systematic Reviews, and several other sources from database inception to March 2017. Study Selection: Intervention trials and observational studies, published in English, involving adults using plant-based cannabis preparations that reported pain, quality of life, or adverse effect outcomes...
August 15, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28806104/repetitive-transcranial-magnetic-stimulation-rtms-administration-to-heavy-cannabis-users
#3
Gregory L Sahlem, Nathaniel L Baker, Mark S George, Robert J Malcolm, Aimee L McRae-Clark
BACKGROUND: Cannabis use disorder (CUD) is a common condition with few treatments. Several studies in other substance use disorders have found that applying repetitive transcranial magnetic stimulation (rTMS) to the dorsolateral prefrontal cortex (DLPFC) decreases cue-elicited craving and possibly decreases use. To date, there have been no studies attempting to use rTMS in CUD. OBJECTIVES: This study was conducted to determine if rTMS could be feasibly delivered to a group of non-treatment seeking CUD participants...
August 14, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28802093/clinical-aspects-of-opium-adulterated-with-lead-in-iran-a-review
#4
Samira Alinejad, Jan Aaseth, Mohammad Abdollahi, Hossein Hassanian-Moghaddam, Omid Mehrpour
Adulteration of drugs with poisonous substances during production or consumption has caused numerous health problems. Among contaminants that have the potential of producing poisonous effects are the heavy metals lead, arsenic and thallium that make up an important group of toxic substances. The emergence of these new health problems related to opioid abuse has precipitated this MiniReview on the status of the most hazardous and common opioid adulterants. In fact, adulterated opium is a major public health problem and can threaten the health of users...
August 12, 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28792900/dynamic-video-stitching-via-shakiness-removing
#5
Yongwei Nie, Tan Su, Zhensong Zhang, Hanqiu Sun, Guiqing Li
Stitching videos captured by hand-held mobile cameras can essentially enhance entertainment experience of ordinary users. However, such videos usually contain heavy shakiness and large parallax, which are challenging to stitch. In this paper, we propose a novel approach of video stitching and stabilization for videos captured by mobile devices. The main component of our method is a unified video stitching and stabilization optimization that computes stitching and stabilization simultaneously rather than does each one individually...
August 7, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28791734/drinking-status-but-not-acute-alcohol-consumption-influences-delay-discounting
#6
Sally Adams, Angela S Attwood, Marcus R Munafò
OBJECTIVE: The aim of this study was to investigate the following: (a) the effects of acute alcohol on delay discounting; (b) the effects of drinking status on delayed discounting; and (c) whether these effects differ according to reward type (alcohol vs. money). METHODS: Heavy and light social alcohol users (n = 96) were randomized to receive either an acute dose of alcohol at 0.4 or 0.6 g/kg or placebo in a between-subjects, double-blind design. Delay discounting of alcohol and monetary rewards was measured using a hyperbolic model, with higher scores indicative of greater delay discounting...
August 9, 2017: Human Psychopharmacology
https://www.readbyqxmd.com/read/28782982/sleep-continuity-architecture-and-quality-among-treatment-seeking-cannabis-users-an-in-home-unattended-polysomnographic-study
#7
Lauren R Pacek, Evan S Herrmann, Michael T Smith, Ryan Vandrey
The objective of the study was to describe self-report and objectively measured sleep characteristics of adult treatment-seeking cannabis users. Study participants (n = 87) were adults who were screened for a 12-week outpatient cannabis treatment research program in Baltimore, MD. Participants completed objective and self-report measures of sleep quality. Data were analyzed for the sample overall and after stratifying by sex (54 men, 33 women). Participants were primarily urban, socioeconomically disadvantaged African Americans...
August 2017: Experimental and Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28768639/a-cross-sectional-study-of-the-relationship-between-the-exposure-of-pregnant-women-to-military-attacks-in-2014-in-gaza-and-the-load-of-heavy-metal-contaminants-in-the-hair-of-mothers-and-newborns
#8
Paola Manduca, Safwat Y Diab, Samir R Qouta, Nabil Ma Albarqouni, Raiija-Leena Punamaki
OBJECTIVE: Metal contamination of humans in war areas has rarely been investigated. Weaponry's heavy metals become environmentally stable war remnants and accumulate in living things. They also pose health risks in terms of prenatal intake, with potential long term risks for reproductive and children's health. We studied the contribution of military attacks to the load of 23 metals in the hair of Palestinian women in the Gaza Strip, who were pregnant at the time of the military attacks in 2014, and their newborns...
August 2, 2017: BMJ Open
https://www.readbyqxmd.com/read/28761084/single-vector-non-leaky-gene-expression-system-for-drosophila-melanogaster
#9
Arslan Akmammedov, Marco Geigges, Renato Paro
An ideal transgenic gene expression system is inducible, non-leaky, and well tolerated by the target organism. While the former has been satisfactorily realized, leakiness and heavy physiological burden imposed by the existing systems are still prominent hurdles in their successful implementation. Here we describe a new system for non-leaky expression of transgenes in Drosophila. PRExpress is based on a single transgenic construct built from endogenous components, the inducible hsp70 promoter and a multimerized copy of a Polycomb response element (PRE) controlled by epigenetic chromatin regulators of the Polycomb group...
July 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28756354/a-latent-class-analysis-of-poly-marijuana-use-among-young-adults
#10
Melissa J Krauss, Biva Rajbhandari, Shaina J Sowles, Edward L Spitznagel, Patricia Cavazos-Rehg
INTRODUCTION: With more states legalizing marijuana use, the marijuana industry has grown, introducing a variety of marijuana products. Our study explores the use of multiple marijuana products (poly-marijuana use) and the characteristics associated with this behavior. METHODS: Past-month marijuana users aged 18-34years were surveyed online via an existing online panel (n=2444). Participants answered questions about past-month use of three types of marijuana (plant-based, concentrates, edibles), marijuana use patterns, and driving after use...
July 14, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28752650/adolescent-alcohol-and-cannabis-use-in-iceland-1995-2015
#11
Arsaell Arnarsson, Gisli Kort Kristofersson, Thoroddur Bjarnason
INTRODUCTION: Over the past two decades, alcohol consumption of Icelandic adolescents has decreased dramatically. The aim of this study was to quantify the extent of this reduction and compare it with the trend in cannabis use over a 20 year period and to identify possible explanations. METHODS: We used data from the Icelandic participants to the European School Survey Project on Alcohol and Other Drugs study (collected via paper-and-pencil questionnaires in classrooms)...
July 28, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28749322/integration-of-slack-a-cloud-based-team-collaboration-application-into-research-coordination
#12
Miriam Gofine, Sunday Clark
Practitioners of epidemiology require efficient real-time communication and shared access to numerous documents in order to effectively manage a study. Much of this communication involves study logistics and does not require use of Protected Health Information. Slack is a team collaboration app; it archives all direct messages and group conversations, hosts documents internally, and integrates with the Google Docs application. Slack has both desktop and mobile applications, allowing users to communicate in real-time without the need to find email addresses or phone numbers or create contact lists...
June 30, 2017: Journal of Innovation in Health Informatics
https://www.readbyqxmd.com/read/28745647/utilization-of-capsules-for-negative-staining-of-viral-samples-within-biocontainment
#13
Candace D Blancett, Mitchell K Monninger, Chrystal A Nguessan, Kathleen A Kuehl, Cynthia A Rossi, Scott P Olschner, Priscilla L Williams, Steven L Goodman, Mei G Sun
Transmission electron microscopy (TEM) is used to observe the ultrastructure of viruses and other microbial pathogens with nanometer resolution. Most biological materials do not contain dense elements capable of scattering electrons to create an image; therefore, a negative stain, which places dense heavy metal salts around the sample, is required. In order to visualize viruses in suspension under the TEM they must be applied to small grids coated with a transparent surface only nanometers thick. Due to their small size and fragility, these grids are difficult to handle and easily moved by air currents...
July 19, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28741422/longitudinal-study-of-hippocampal-volumes-in-heavy-cannabis-users
#14
L Koenders, V Lorenzetti, L de Haan, C Suo, Wam Vingerhoets, W van den Brink, R W Wiers, C J Meijer, Mwj Machielsen, A E Goudriaan, D J Veltman, M Yücel, J Cousijn
BACKGROUND: Cannabis exposure, particularly heavy cannabis use, has been associated with neuroanatomical alterations in regions rich with cannabinoid receptors such as the hippocampus in some but not in other (mainly cross-sectional) studies. However, it remains unclear whether continued heavy cannabis use alters hippocampal volume, and whether an earlier age of onset and/or a higher dosage exacerbate these changes. METHODS: Twenty heavy cannabis users (mean age 21 years, range 18-24 years) and 23 matched non-cannabis using healthy controls were submitted to a comprehensive psychological assessment and magnetic resonance imaging scan at baseline and at follow-up (average of 39 months post-baseline; standard deviation=2...
August 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28724089/grower-analysis-of-organic-matter-amendments-in-california-orchards
#15
Sat Darshan S Khalsa, Patrick H Brown
Organic matter amendments supply crop nutrients and enhance soil health, yet information specific to orchards is lacking. A survey was conducted to analyze use of these materials by California almond [ (Mill.) D.A. Webb] growers. Significant differences were observed for benefits, concerns, and accessibility to manure and green waste sources and between users and nonusers. Use patterns were significantly influenced by heavy and light users, farm size, and geographic region. Enhanced soil biology was the main benefit attributed to organic matter amendments by both users and nonusers...
May 2017: Journal of Environmental Quality
https://www.readbyqxmd.com/read/28721960/alcohol-consumption-hazardous-drinking-and-alcohol-dependency-among-the-population-of-andaman-and-nicobar-islands-india
#16
Sathya Prakash Manimunda, Attayuru Purushottaman Sugunan, Kandavelu Thennarasu, Dhanasekara Pandian, Kasturi S Pesala, Vivek Benegal
BACKGROUND: Harmful use of alcohol is one of the globally recognized causes of health hazards. There are no data on alcohol consumption from Andaman and Nicobar Islands. OBJECTIVE: The objective of the study was to assess the prevalence and pattern of alcohol use among the population of Andaman and Nicobar Islands, India. METHODS: A representative sample of 18,018 individuals aged ≥14 years were chosen by multistage random sampling and administered a structured instrument, a modified version of the Gender, Alcohol, and Culture: An International Study (GENACIS) which included sociodemographic details and Alcohol Use Disorders Identification Test (AUDIT)...
April 2017: Indian Journal of Public Health
https://www.readbyqxmd.com/read/28717382/neurological-soft-signs-in-tunisian-patients-with-first-episode-psychosis-and-relation-with-cannabis-use
#17
Ahmed Mhalla, Bochra Ben Mohamed, Christoph U Correll, Badii Amamou, Anouar Mechri, Lotfi Gaha
BACKGROUND: Neurological soft signs (NSS) are minor non-localizing neurological abnormalities that are conceptualized as neurodevelopmental markers that mediate the biological risk for psychosis. We aimed to explore the relationship between NSS and cannabis use, an environmental risk factor of psychosis. METHODS: This was a cross-sectional study in consecutively admitted patients hospitalized for first-episode psychosis. NSS were assessed by the NSS scale (23 items exploring motor coordination, motor integrative function, sensory integration, involuntary movements or posture, quality of lateralization)...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/28715729/consistent-association-between-hypnotics-sedatives-and-non-traffic-injuries-results-from-a-national-household-survey
#18
María Del Mar Martín-Rodríguez, José Pulido, Eladio Jiménez-Mejías, Juan Hoyos, Pablo Lardelli-Claret, Gregorio Barrio
AIM: To quantify the relationship between patterns of psychostimulants, hypnotics/sedatives and alcohol consumption and the frequency of unintentional non-traffic injuries (UNTIs) requiring medical assistant in Spain. METHODS: We carried out a cross sectional study using a randomized pooled sample from two household surveys on psychoactive drugs use (n=51,649 subjects aged 15-64 years). We estimated the magnitude of the association between the use of psychostimulants and hypnotics/sedatives in the last 12 months as well as alcohol consumption in the last 30days with the occurrence of UNTIs in the last 12 months (falls, knocks/bumps and cuts) by building several logistic regression models, which took into account the effect of sociodemographic characteristics and the use of other psychoactive drugs (including cannabis)...
July 14, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28678870/answering-the-missed-call-initial-exploration-of-cognitive-and-electrophysiological-changes-associated-with-smartphone-use-and-abuse
#19
Aviad Hadar, Itay Hadas, Avi Lazarovits, Uri Alyagon, Daniel Eliraz, Abraham Zangen
BACKGROUND: Smartphone usage is now integral to human behavior. Recent studies associate extensive usage with a range of debilitating effects. We sought to determine whether excessive usage is accompanied by measurable neural, cognitive and behavioral changes. METHOD: Subjects lacking previous experience with smartphones (n = 35) were compared to a matched group of heavy smartphone users (n = 16) on numerous behavioral and electrophysiological measures recorded using electroencephalogram (EEG) combined with transcranial magnetic stimulation (TMS) over the right prefrontal cortex (rPFC)...
2017: PloS One
https://www.readbyqxmd.com/read/28673527/marijuana-use-in-the-context-of-alcohol-interventions-for-mandated-college-students
#20
Ali M Yurasek, Jennifer E Merrill, Jane Metrik, Mary Beth Miller, Anne C Fernandez, Brian Borsari
OBJECTIVE: Concurrent use of marijuana and alcohol among college students is highly prevalent and associated with negative consequences. It remains unclear whether marijuana use is influenced by or lessens the efficacy of alcohol interventions delivered within a stepped-care approach. METHOD: Participants were 530 college students who violated campus alcohol policy and were mandated to an alcohol-focused brief advice (BA) session. Participants who reported continued risky alcohol use (4+ heavy drinking episodes and/or 5+ alcohol-related consequences in the past month) six weeks following the BA session were randomized to a brief motivational intervention (BMI; n=211) or assessment only (AO; n=194) condition...
August 2017: Journal of Substance Abuse Treatment
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