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https://www.readbyqxmd.com/read/29329371/alcohol-use-in-adolescence-and-later-working-memory-findings-from-a-large-population-based-birth-cohort
#1
Liam Mahedy, Matt Field, Suzanne Gage, Gemma Hammerton, Jon Heron, Matt Hickman, Marcus R Munafò
Aims: The study aimed to examine the association between adolescent alcohol use and working memory (WM) using a large population sample. Methods: Data from the Avon Longitudinal Study of Parents and Children were used to investigate the association between alcohol use at age 15 years and WM 3 years later, assessed using the N-back task (N ~ 3300). A three-category ordinal variable captured mutually exclusive alcohol groupings ranging in order of severity (i.e. low alcohol users, frequent drinkers and frequent/binge drinkers)...
January 10, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/29319619/history-of-marijuana-use-does-not-affect-outcomes-on-the-liver-transplant-waitlist
#2
Prashant Kotwani, Varun Saxena, Jennifer L Dodge, John Roberts, Francis Yao, Bilal Hameed
BACKGROUND: Data are limited on marijuana use and its impact on liver transplant (LT) waitlist outcomes. We aimed to assess the risk of waitlist mortality/delisting and likelihood of LT among prior marijuana users, and to determine the prevalence and factors associated with marijuana use. METHODS: Retrospective cohort of adults evaluated for LT over 2 years at a large LT center. Marijuana use defined by self-report in psychosocial assessment and/or positive urine toxicology...
January 10, 2018: Transplantation
https://www.readbyqxmd.com/read/29311404/recreational-drug-and-psychosocial-profile-in-chronic-hepatitis-c-patients-seeking-antiviral-therapy
#3
Nayana George, Sherrie M Harrell, Kimberly D Rhodes, Andres Duarte-Rojo
BACKGROUND AND AIMS: Practitioners treating hepatitis C (HCV) provide healthcare to a special population with high rates of substance abuse and psychiatric disorders. We investigated the psychosocial profile in HCV patients and tested what variables affect commencement of antiviral therapy. MATERIAL AND METHODS: Recreational drug use (RDU), marijuana (THC), alcohol use, and psychiatric history were initially investigated with a questionnaire prior to history and physical...
December 27, 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/29311169/prescription-opioid-use-and-satisfaction-with-care-among-adults-with-musculoskeletal-conditions
#4
Brian D Sites, Jordon Harrison, Michael D Herrick, Melissa M Masaracchia, Michael L Beach, Matthew A Davis
PURPOSE: In the current payment paradigm, reimbursement is partially based on patient satisfaction scores. We sought to understand the relationship between prescription opioid use and satisfaction with care among adults who have musculoskeletal conditions. METHODS: We performed a cross-sectional study using nationally representative data from the 2008-2014 Medical Expenditure Panel Survey. We assessed whether prescription opioid use is associated with satisfaction with care among US adults who had musculoskeletal conditions...
January 2018: Annals of Family Medicine
https://www.readbyqxmd.com/read/29298708/case-study-of-a-user-driven-prosthetic-arm-design-bionic-hand-versus-customized-body-powered-technology-in-a-highly-demanding-work-environment
#5
Wolf Schweitzer, Michael J Thali, David Egger
BACKGROUND: Prosthetic arm research predominantly focuses on "bionic" but not body-powered arms. However, any research orientation along user needs requires sufficiently precise workplace specifications and sufficiently hard testing. Forensic medicine is a demanding environment, also physically, also for non-disabled people, on several dimensions (e.g., distances, weights, size, temperature, time). METHODS: As unilateral below elbow amputee user, the first author is in a unique position to provide direct comparison of a "bionic" myoelectric iLimb Revolution (Touch Bionics) and a customized body-powered arm which contains a number of new developments initiated or developed by the user: (1) quick lock steel wrist unit; (2) cable mount modification; (3) cast shape modeled shoulder anchor; (4) suspension with a soft double layer liner (Ohio Willowwood) and tube gauze (Molnlycke) combination...
January 3, 2018: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29297719/perceptions-of-alcohol-advertising-among-high-risk-drinkers
#6
Jonathan K Noel, Ziming Xuan, Thomas F Babor
BACKGROUND: Individuals who are particularly vulnerable to the influence of alcohol advertising, such as youth, need special protections, yet little research has been done to determine if other vulnerable groups exist. Secondary data analysis was conducted to determine if perceptions of alcohol advertising differ between groups based on their alcohol use and whether the definition of "vulnerable" should be expanded beyond demographic categories. METHODS: Students (n = 326) from 2 U...
January 3, 2018: Substance Use & Misuse
https://www.readbyqxmd.com/read/29276705/are-exposures-to-multiple-frequencies-the-key-to-future-radiofrequency-research
#7
REVIEW
Zenon Sienkiewicz, Carolina Calderón, Kerry A Broom, Darren Addison, Amélie Gavard, Louise Lundberg, Myron Maslanyj
There is an extensive literature investigating possible effects of exposure to radiofrequency (RF) electromagnetic fields associated with mobile phone technologies. This has not identified any public health risks with any degree of certainty. Some epidemiological studies have observed associations between heavy users of mobile phones and some types of cancer, but animal studies do not support this association, although a few studies have reported increased tumor yields. However, there is a crucial difference between epidemiology studies and laboratory work in terms of signals investigated: most people are exposed to a complex mixture of frequencies and signals at varying intensities, whereas the majority of animal studies have been performed using a single frequency or intensity...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29276495/verbal-learning-and-memory-in-cannabis-and-alcohol-users-an-event-related-potential-investigation
#8
Janette L Smith, Frances M De Blasio, Jaimi M Iredale, Allison J Matthews, Raimondo Bruno, Michelle Dwyer, Tessa Batt, Allison M Fox, Nadia Solowij, Richard P Mattick
Aims: Long-term heavy use of cannabis and alcohol are known to be associated with memory impairments. In this study, we used event-related potentials to examine verbal learning and memory processing in a commonly used behavioral task. Method: We conducted two studies: first, a small pilot study of adolescent males, comprising 13 Drug-Naive Controls (DNC), 12 heavy drinkers (HD) and 8 cannabis users (CU). Second, a larger study of young adults, comprising 45 DNC (20 female), 39 HD (16 female), and 20 CU (9 female)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29248450/evaluating-the-hematological-and-clinical-chemistry-parameters-of-kratom-mitragyna-speciosa-users-in-malaysia
#9
Darshan Singh, Christian P Müller, Vikneswaran Murugaiyah, Shahrul Bariyah Sahul Hamid, Balasingam K Vicknasingam, Bonnie Avery, Nelson Jeng Yeou Chear, Sharif Mahsufi Mansor
ETHNOPHARMACOLOGICAL RELEVANCE: Kratom (Mitragyna speciosa Korth.) from the Rubiaceae family is an indigenous tropical medicinal tree of Southeast Asia. Kratom leaves have been used for decades in Malaysia and Thailand in traditional context for its perceived vast medicinal value, and as a mild stimulant among manual labourers. Kratom consumption has been reported to cause side-effects in kratom users. AIM OF THE STUDY: To evaluate kratom's effects towards hematological and clinical-chemistry parameters among regular kratom users in Malaysia...
December 14, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29240535/factors-associated-with-waterpipe-tobacco-smoking-among-lebanese-women
#10
Karim N Daou, Ibrahim R Bou-Orm, Salim M Adib
INTRODUCTION: Waterpipe tobacco smoking (WTS) has become a serious public health threat in the Middle-East and beyond. OBJECTIVES: To estimate the prevalence rates of cigarette and WTS among Lebanese women and describe characteristics associated with each behavior. METHODS: Secondary analysis of women's health data obtained in a national survey in 2010. RESULTS: Of 2255 selected women, 78% reported no or past long-term WTS...
December 14, 2017: Women & Health
https://www.readbyqxmd.com/read/29178411/increased-plasma-oleoylethanolamide-and-palmitoleoylethanolamide-levels-correlate-with-inflammatory-changes-in-alcohol-binge-drinkers-the-case-of-hmgb1-in-women
#11
María Antón, Alicia Rodríguez-González, Inmaculada Concepción Rodríguez-Rojo, Antoni Pastor, Ángeles Correas, Antonia Serrano, Antonio Ballesta, Francisco Alén, Raquel Gómez de Heras, Rafael de la Torre, Fernando Rodríguez de Fonseca, Laura Orio
Alcohol binge drinking is a heavy pattern of alcohol consumption increasingly used by young people. In a previous study, we reported that young drinkers with a 2-year history of binge alcohol consumption had an overactivation of the innate immune system and peripheral inflammation when compared with controls. In the present study, we measured several biolipids that are fatty acid derivatives belonging to the acylethanolamide or 2-acylglycerol families in the plasma of the same subjects (n = 42; 20 men and 22 women)...
November 27, 2017: Addiction Biology
https://www.readbyqxmd.com/read/29176832/a-user-exposure-based-approach-for-non-structural-road-network-vulnerability-analysis
#12
Lei Jin, Haizhong Wang, Binglei Xie, Le Yu, Lin Liu
Aiming at the dense urban road network vulnerability without structural negative consequences, this paper proposes a novel non-structural road network vulnerability analysis framework. Three aspects of the framework are mainly described: (i) the rationality of non-structural road network vulnerability, (ii) the metrics for negative consequences accounting for variant road conditions, and (iii) the introduction of a new vulnerability index based on user exposure. Based on the proposed methodology, a case study in the Sioux Falls network which was usually threatened by regular heavy snow during wintertime is detailedly discussed...
2017: PloS One
https://www.readbyqxmd.com/read/29176274/increased-incidence-of-visual-field-abnormalities-as-determined-by-frequency-doubling-technology-perimetry-in-high-computer-users-among-japanese-workers-a-retrospective-cohort-study
#13
Tadashi Nakano, Takeshi Hayashi, Toru Nakagawa, Toru Honda, Satoshi Owada, Hitoshi Endo, Masayuki Tatemichi
BACKGROUND: This retrospective cohort study primarily aimed to investigate the possible association of computer use with visual field abnormalities (VFA) among Japanese workers. METHODS: The study included 2,377 workers (mean age 45.7 [standard deviation, 8.3] years; 2,229 men and 148 women) who initially exhibited no VFA during frequency doubling technology perimetry (FDT) testing. Subjects then underwent annual follow-up FDT testing for 7 years, and VFA were determined using a FDT-test protocol (FDT-VFA)...
November 25, 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/29169317/hashclone-a-new-tool-to-quantify-the-minimal-residual-disease-in-b-cell-lymphoma-from-deep-sequencing-data
#14
Marco Beccuti, Elisa Genuardi, Greta Romano, Luigia Monitillo, Daniela Barbero, Mario Boccadoro, Marco Ladetto, Raffaele Calogero, Simone Ferrero, Francesca Cordero
BACKGROUND: Mantle Cell Lymphoma (MCL) is a B cell aggressive neoplasia accounting for about the 6% of all lymphomas. The most common molecular marker of clonality in MCL, as in other B lymphoproliferative disorders, is the ImmunoGlobulin Heavy chain (IGH) rearrangement, occurring in B-lymphocytes. The patient-specific IGH rearrangement is extensively used to monitor the Minimal Residual Disease (MRD) after treatment through the standardized Allele-Specific Oligonucleotides Quantitative Polymerase Chain Reaction based technique...
November 23, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/29161378/health-behaviours-as-a-predictor-of-quitting-hazardous-alcohol-use-in-the-stockholm-public-health-cohort
#15
Eleonor Säfsten, Yvonne Forsell, Mats Ramstedt, Maria R Galanti
Background: Adopting healthy behaviours may facilitate the transition from hazardous to non-hazardous use of alcohol, yet, longitudinal studies of health behaviours in relation to the cessation of hazardous alcohol use are rare. We addressed this question using data from a large population-based cohort of adults in Sweden (Stockholm Public Health Cohort). Methods: Participants from two sub-cohorts (inception in 2002 and 2010), with follow-up until the year 2014 were included...
November 17, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/29127656/altered-oscillatory-brain-dynamics-of-emotional-processing-in-young-binge-drinkers
#16
Siyuan Huang, Lee A Holcomb, Stephen M Cruz, Ksenija Marinkovic
Heavy episodic drinking, also termed binge drinking, is commonly practiced by young adults. It is accompanied by a range of cognitive, affective, and social problems, but the neural dynamics underlying changes in emotional functions is poorly understood. To investigate the behavioral and brain indices of affective processing as a function of binge drinking, young, healthy participants (23.3 ± 3.3 years) were assigned to two groups (n = 32 each) based on their drinking habits. Binge drinking (BD) participants reported drinking heavily with at least five binge episodes in the last 6 months, whereas light drinkers (LD) reported no more than one binge episode in the last 6 months...
November 10, 2017: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/29117267/the-impact-of-cannabis-use-on-patients-enrolled-in-opioid-agonist-therapy-in-ontario-canada
#17
Alexandra M Franklyn, Joseph K Eibl, Graham J Gauthier, David C Marsh
BACKGROUND: With the Canadian government legalizing cannabis in the year 2018, the potential harms to certain populations-including those with opioid use disorder-must be investigated. Cannabis is one of the most commonly used substances by patients who are engaged in medication-assisted treatment for opioid use disorder, the effects of which are largely unknown. In this study, we examine the impact of baseline and ongoing cannabis use, and whether these are impacted differentially by gender...
2017: PloS One
https://www.readbyqxmd.com/read/29115817/low-cost-chemical-responsive-adhesive-sensing-chips
#18
Weirui Tan, Liyuan Zhang, Wei Shen
Chemical-responsive adhesive sensing chip is a new low-cost analytical platform, which uses adhesive tape loaded with indicator reagents to detect or quantify the target analytes by directly sticking the tape to the samples of interest. The chemical-responsive adhesive sensing chips can be used with paper to analyse aqueous samples; they can also be used to detect and quantify solid, particulate and powder analytes. The colorimetric indicators become immediately visible as the contact between the functionalized adhesives and target samples was made...
November 8, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29097069/dose-related-ethanol-intake-cx43-and-nav1-5-remodeling-exploring-insights-of-altered-ventricular-conduction-and-qrs-fragmentation-in-excessive-alcohol-users
#19
Chung-Lieh Hung, Yu-Jun Lai, Po-Ching Chi, Liang-Chia Chen, Ya-Ming Tseng, Jen-Yuan Kuo, Cheng-I Lin, Yao-Chang Chen, Shing-Jong Lin, Hung-I Yeh
BACKGROUND: Chronic, excessive ethanol intake has been linked with various electrical instabilities, conduction disturbances, and even sudden cardiac death, but the underlying cause for the latter is insufficiently delineated. METHODS: We studied surface electrocardiography (ECG) in a community-dwelling cohort with moderate-to-heavy daily alcohol intake (grouped as >90g/day, ≤90g/day, and nonintake). RESULTS: Compared with nonintake, heavier alcohol users showed markedly widened QRS duration and higher prevalence of QRS fragmentation (64...
October 31, 2017: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/29062186/lead-poisoning-due-to-herbal-medications
#20
Prashant Sakharkar
Many herbal products are harmless or possess minimal toxicity, whereas, some contain toxic ingredients that may not be identified due to lack of quality control or not listed on the label. Over the years, several case reports and studies have documented that herbal medications may contain ingredients that are toxic. Several studies have documented that some herbal medications contained high concentrations of heavy metals, such as lead, mercury, and arsenic. Publications of such case reports and studies have repeatedly reminded us that we have failed in our legal and civic duties of educating users of herbal medications and general population about the grave concerns posed by the herbal medications and their associated toxicities...
October 2017: Indian Journal of Clinical Biochemistry: IJCB
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