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https://www.readbyqxmd.com/read/28534647/considering-built-environment-and-spatial-correlation-in-modelling-pedestrian-injury-severity
#1
Carlo G Prato, Sigal Kaplan, Alexandre Patrier, Thomas K Rasmussen
OBJECTIVE: This study looks at mitigating and aggravating factors that are associated with the injury severity of pedestrians when they have crashes with another road user and overcomes existing limitations in the literature by posing attention on the built environment and considering spatial correlation across crashes. METHOD: Reports for 6539 pedestrian crashes occurred in Denmark between 2006 and 2015 were merged with geographic information system resources containing detailed information about built environment and exposure at the crash locations...
May 23, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28530429/a-daily-diary-examination-of-caffeine-mixed-with-alcohol-among-college-students
#2
Ashley N Linden-Carmichael, Cathy Lau-Barraco
OBJECTIVE: Caffeinated alcoholic beverage (CAB) use is associated with a range of substance-related problems. The majority of prior research on CABs is based on cross-sectional and retrospective reports, which do not account for intraindividual differences in use and may be subject to recall biases. The current research used a daily diary, within-subjects design to compare days where individuals simultaneously mixed alcohol with caffeine (CAB days) and days where individuals drank other types of alcohol (non-CAB days) on alcohol use outcomes...
May 22, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28518070/sample-preparation-for-mass-cytometry-analysis
#3
Ryan L McCarthy, Aundrietta D Duncan, Michelle C Barton
Mass cytometry utilizes antibodies conjugated with heavy metal labels, an approach that has greatly increased the number of parameters and opportunities for deep analysis well beyond what is possible with conventional fluorescence-based flow cytometry. As with any new technology, there are critical steps that help ensure the reliable generation of high-quality data. Presented here is an optimized protocol that incorporates multiple techniques for the processing of cell samples for mass cytometry analysis. The methods described here will help the user avoid common pitfalls and achieve consistent results by minimizing variability, which can lead to inaccurate data...
April 29, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28510803/occupational-and-life-style-factors-acquired-mutagenicity-in-agric-workers-of-northeastern-brazil
#4
Tatiana Vieira Souza Chaves, Muhammad Torequl Islam, Manoel Odoríco de Moraes, Marcus Vinícius Oliveira Barros de Alencar, Débora Cássia Vieira Gomes, Rodrigo Mendes de Carvalho, Sharbel Weider Maluf, Fabrício Pires de Moura do Amaral, Márcia Fernanda Correia Jardim Paz, Gilberto Santos Cerqueira, Hercília Maria Lins Rolim, João Marcelo de Castro E Sousa, Ana Amélia de Carvalho Melo-Cavalcante, Maria Elisabete Amaral de Moraes
Pesticides are a complex mixture of chemicals used to protect crops from a number of pests and diseases. They have been considered as potential mutagenic agents. This study aims at evaluation of the mutagenic effect of pesticide exposure to agricultural workers through chromosomal aberrations (CA) and micronucleus (MN) assay in peripheral blood lymphocytes and oral mucosal cells, respectively. The exposed group was consisted with 97 farmers, while the control (un-exposed) group consisted of 55. The results showed a significant (p < 0...
May 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28510780/design-and-testing-of-a-new-diatom-based-index-for-heavy-metal-pollution
#5
M R Fernández, G Martín, J Corzo, A de la Linde, E García, M López, M Sousa
The Tinto and Odiel river basins (SW Spain) are known worldwide for their unique water characteristics. Such uniqueness is a consequence of their flow through the Iberian Pyrite Belt (an area rich in metal sulphides) and the mining activities in the basins. A process of sulphide oxidation occurs in this region, which acidifies the water and increases the amount of heavy metals in it. As a result, the rivers suffer the so-called "acid mine drainage" (AMD). Traditional biotic diatom-based indexes (IPS, IBD, EPI-D, etc...
May 16, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28509863/a-fairness-oriented-neighbor-channel-aware-mac-protocol-for-airborne-sensor-networks
#6
Xiaolin Gao, Jian Yan, Jianhua Lu
In airborne sensor networks (ASNs), the media access control (MAC) protocol faces a serious unfairness problem due to the traditional protection mechanism of air-to-air communications among aircraft. Actually, by using the binary exponential back-off algorithm at high traffic loads to minimize collisions among users, the latest successful node can always benefit from this kind of MAC to obtain channel resources. Moreover, when taking the existence of the hidden nodes in ASNs into account, the inaccurate traffic load information will further aggravate the system's unfairness...
May 16, 2017: Sensors
https://www.readbyqxmd.com/read/28499790/self-monitoring-blood-glucose-test-strip-utilization-in-saskatchewan-a-retrospective-study
#7
Lynette Kosar, Wasem Alsabbagh, Xinya Lu, Lisa M Lix, Yvonne Shevchuk, Gary F Teare, Anne Champagne, David F Blackburn
OBJECTIVES: To describe trends in blood glucose test strip (TS) utilization and cost in Saskatchewan. METHODS: A retrospective analysis of TS use between January 1, 1996, and December 31, 2013, was conducted using population-based health administrative databases in Saskatchewan. The prescription drug database was used to describe the annual number of TS dispensations, the number of strips dispensed, the number of unique beneficiaries and the total costs. A patient-level analysis was also carried out to describe the patterns of TS use (i...
May 9, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28498718/effects-of-regular-cannabis-use-on-neurocognition-brain-structure-and-function-a-systematic-review-of-findings-in-adults
#8
Danilo A Nader, Zila M Sanchez
BACKGROUND: Cannabis is the most used illicit drug worldwide. The long-standing consequences for the central nervous system associated with frequent cannabis use have not been well delineated and should be determined. OBJECTIVE: To review recent studies on the effects of regular cannabis use regarding its effects on cognition, brain structure, and function in adults. METHODS: A systematic literature review was conducted by performing electronic searches in the PubMed, LILACS, and SciELO databases (2010-2016)...
May 12, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28472367/pigspro-prediction-of-immunoglobulin-structures-v2
#9
Rosalba Lepore, Pier P Olimpieri, Mario A Messih, Anna Tramontano
PIGSpro is a significant upgrade of the popular PIGS server for the prediction of the structure of immunoglobulins. The software has been completely rewritten in python following a similar pipeline as in the original method, but including, at various steps, relevant modifications found to improve its prediction accuracy, as demonstrated here. The steps of the pipeline include the selection of the appropriate framework for predicting the conserved regions of the molecule by homology; the target template alignment for this portion of the molecule; the selection of the main chain conformation of the hypervariable loops according to the canonical structure model, the prediction of the third loop of the heavy chain (H3) for which complete canonical structures are not available and the packing of the light and heavy chain if derived from different templates...
May 4, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28469423/prior-delinquency-and-depression-differentially-predict-conditional-associations-between-discrete-patterns-of-adolescent-religiosity-and-adult-alcohol-use-patterns
#10
Meredith A Hoyland, Wade C Rowatt, Shawn J Latendresse
Prior research has demonstrated that adolescent delinquency and depression are prospectively related to adult alcohol use and that adolescent religiosity may influence these relationships. However, such associations have not been investigated using person-centered approaches that provide nuanced explorations of these constructs. Using data from the National Longitudinal Study of Adolescent to Adult Health, we examined whether adolescent delinquency and depression differentiated typologies of adult alcohol users and whether these relationships varied across religiosity profiles...
2017: Substance Abuse: Research and Treatment
https://www.readbyqxmd.com/read/28467055/microfluidic-technology-uncovering-the-mechanisms-of-nanocrystal-nucleation-and-growth
#11
Ioannis Lignos, Richard Maceiczyk, Andrew J deMello
The controlled and reproducible formation of colloidal semiconductor nanocrystals (or quantum dots) is of central importance in nanoscale science and technology. The tunable size- and shape-dependent properties of such materials make them ideal candidates for the development of efficient and low-cost displays, solar cells, light-emitting devices, and catalysts. The formidable difficulties associated with the macroscale preparation of semiconductor nanocrystals (possessing bespoke optical and chemical properties) result from the fact that underlying reaction mechanisms are complex and that the reactive environment is difficult to control...
May 3, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28459283/impact-of-improving-vehicle-front-design-on-the-burden-of-pedestrian-injuries-in-germany-usa-and-india
#12
Dane Moran, Dipan Bose, Kavi Bhalla
OBJECTIVE: European car design regulations and New Car Assessment Program (NCAP) ratings have led to reductions in pedestrian injuries. The aim of this study was to evaluate the impact of improving vehicle front design on mortality and morbidity due to pedestrian injuries in a European country (Germany) and two countries, (USA, and India) that do not have pedestrian-focused NCAP testing or design regulations. METHODS: We used data from the International Road Traffic and Accident Database and the Global Burden of Disease project to estimate baseline pedestrian deaths and non-fatal injuries in each country in 2013...
May 1, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28448058/a-rapid-automated-protocol-for-muscle-fiber-population-analysis-in-rat-muscle-cross-sections-using-myosin-heavy-chain-immunohistochemistry
#13
Konstantin D Bergmeister, Marion Gröger, Martin Aman, Anna Willensdorfer, Krisztina Manzano-Szalai, Stefan Salminger, Oskar C Aszmann
Quantification of muscle fiber populations provides a deeper insight into the effects of disease, trauma, and various other influences on skeletal muscle composition. Various time-consuming methods have traditionally been used to study fiber populations in many fields of research. However, recently developed immunohistochemical methods based on myosin heavy chain protein expression provide a quick alternative to identify multiple fiber types in a single section. Here, we present a rapid, reliable and reproducible protocol for improved staining quality, allowing automatic acquisition of whole cross sections and automatic quantification of fiber populations with ImageJ...
March 28, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28430155/dynamic-construction-scheme-for-virtualization-security-service-in-software-defined-networks
#14
Zhaowen Lin, Dan Tao, Zhenji Wang
For a Software Defined Network (SDN), security is an important factor affecting its large-scale deployment. The existing security solutions for SDN mainly focus on the controller itself, which has to handle all the security protection tasks by using the programmability of the network. This will undoubtedly involve a heavy burden for the controller. More devastatingly, once the controller itself is attacked, the entire network will be paralyzed. Motivated by this, this paper proposes a novel security protection architecture for SDN...
April 21, 2017: Sensors
https://www.readbyqxmd.com/read/28427364/national-alcohol-survey-of-households-in-trinidad-and-tobago-nashtt-alcohol-use-in-households
#15
R G Maharaj, M S Motilal, T Babwah, P Nunes, R Brathwaite, G Legall, S D Reid, M E Canavan, E H Bradley
BACKGROUND: To determine the patterns of alcohol use among households in Trinidad and Tobago (T&T) and to estimate the association between alcohol use and negative psychological, social, or physical events experienced by the household. METHODS: A convenience sample of 1837 households across T&T. We identified bivariate correlates of alcohol use, and heavy episodic drinking using chi-square and t-test analyses and used multivariable logistic regression to estimate adjusted associations between household alcohol use and experiences within the past 12 months adjusted for sociodemographic covariates...
April 20, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28425095/psychomotor-tremor-and-proprioceptive-control-problems-in-current-and-former-stimulant-drug-users-an-accelerometer-study-of-heavy-users-of-amphetamine-mdma-and-other-recreational-stimulants
#16
Luke A Downey, Brenda Tysse, Talitha C Ford, Angela C Samuels, Rory P Wilson, Andrew C Parrott
The recreational use of various stimulant drugs has been implicated in the development of movement disorders through dysregulation of the dopaminergic and serotoninergic neurotransmitter systems. The present study investigated psychomotor differences in current and former recreational stimulant drug users compared with nonusing controls. Sixty participants comprised 3 groups: 20 current stimulant drug users (CSUs; 11 men, aged 31.4 ± 9.1 years), 20 former stimulant drug users (FSUs; 5 men, aged 39.1 ± 8.5 years), and 20 nonuser controls (NUCs; 5 men, aged 35...
April 19, 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28422803/marijuana-use-and-self-reported-quality-of-eyesight
#17
Obinna F Akano
PURPOSE: There is increasing use of marijuana among young adults and more states in the United States are legalizing medical marijuana use. A number of studies have revealed both the beneficial and harmful effects of marijuana to the human system. Despite some beneficial effects, studies have shown marijuana to have a lot of deleterious effects on the visual system, which subsequently reduces the quality of eyesight. The aim of this study was to investigate if heavy marijuana smoking is associated with a poor quality of eyesight compared with light/no use of marijuana...
May 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28422460/an-evaluation-of-plaque-and-gingivitis-reduction-following-home-use-of-sonicare-flexcare-platinum-with-premium-plaque-control-brush-head-and-a-manual-toothbrush
#18
Wendy Jenkins, Sonia Souza, Marilyn Ward, Jodi Defenbaugh, Kimberly R Milleman, Jeffery L Milleman
OBJECTIVES: To assess the effect of the Philips Sonicare FlexCare Platinum with Premium plaque control brush head on gingival inflammation, bleeding, and supragingival plaque reduction following a six-week period of home use compared to a manual toothbrush. METHODS: This was a randomized, single-blind, parallel-design clinical trial. Subjects included in the study were routine manual toothbrush users who were generally healthy non-smokers, aged 18-65 years, with mild to moderate gingivitis...
March 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28419776/the-involuntary-nature-of-binge-drinking-goal-directedness-and-awareness-of-intention
#19
Nuria Doñamayor, Daniela Strelchuk, Kwangyeol Baek, Paula Banca, Valerie Voon
Binge drinking represents a public health issue and is a known risk factor in the development of alcohol use disorders. Previous studies have shown behavioural as well as neuroanatomical alterations associated with binge drinking. Here, we address the question of the automaticity or involuntary nature of the behaviour by assessing goal-directed behaviour and intentionality. In this study, we used a computational two-step task, designed to discern between model-based/goal-directed and model-free/habitual behaviours, and the classic Libet clock task, to study intention awareness, in a sample of 31 severe binge drinkers (BD) and 35 matched healthy volunteers...
April 16, 2017: Addiction Biology
https://www.readbyqxmd.com/read/28415281/stochastic-dynamics-and-the-predictability-of-big-hits-in-online-videos
#20
José M Miotto, Holger Kantz, Eduardo G Altmann
The competition for the attention of users is a central element of the Internet. Crucial issues are the origin and predictability of big hits, the few items that capture a big portion of the total attention. We address these issues analyzing 10^{6} time series of videos' views from YouTube. We find that the average gain of views is linearly proportional to the number of views a video already has, in agreement with usual rich-get-richer mechanisms and Gibrat's law, but this fails to explain the prevalence of big hits...
March 2017: Physical Review. E
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