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https://www.readbyqxmd.com/read/28918269/excess-social-media-use-in-normal-populations-is-associated-with-amygdala-striatal-but-not-with-prefrontal-morphology
#1
Qinghua He, Ofir Turel, Damien Brevers, Antoine Bechara
This study aims to investigate the gray matter volume (GMV) of key neural systems possibly associated with Excess Social Media Use (ESMU) in the general user population. It employs a sex-balanced case (relatively high ESMU scores) - control (relatively low ESMU scores) design with 50 random university students who have reported varying levels of ESMU. The case and control groups included 25 subjects each. Brain volumes were calculated with Voxel-Based Morphometry techniques applied to structural MRI scans. Results based on voxel-wise and region-of-interest (ROI) analyses showed that the case group had reduced GMV in the bilateral amygdala and right ventral striatum...
September 9, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28918223/an-ecological-model-to-factors-associated-with-booster-seat-use-a-population-based-study
#2
Sarit Shimony Kanat, Rosa Gofin
Belt-positioning booster seat use (BPB) is an effective technology to prevent severe child injury in cases of car crash. However, in many countries, age-appropriate car restraint use for children aged 4-7 years old remains the lowest among all age groups. The aim of this study was to identify the main determinants of BPB use through a comprehensive approach. An ecological model was used to analyze individual, parent-child relationships, and neighborhood characteristics. Parents of children enrolled in the first and second grades completed a self-reported questionnaire (n=745)...
September 14, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28917392/description-of-a-multi-university-education-and-collaborative-care-child-psychiatry-access-program-new-york-state-s-cap-pc
#3
D L Kaye, V Fornari, M Scharf, W Fremont, R Zuckerbrot, C Foley, T Hargrave, B A Smith, J Wallace, G Blakeslee, J Petras, S Sengupta, J Singarayer, A Cogswell, I Bhatia, P Jensen
OBJECTIVE: Although, child mental health problems are widespread, few get adequate treatment, and there is a severe shortage of child psychiatrists. To address this public health need many states have adopted collaborative care programs to assist primary care to better assess and manage pediatric mental health concerns. This report adds to the small literature on collaborative care programs and describes one large program that covers most of New York state. PROGRAM DESCRIPTION: CAP PC, a component program of New York State's Office of Mental Health (OMH) Project TEACH, has provided education and consultation support to primary care providers covering most of New York state since 2010...
September 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28917133/waiting-for-lexical-access-cochlear-implants-or-severely-degraded-input-lead-listeners-to-process-speech-less-incrementally
#4
Bob McMurray, Ashley Farris-Trimble, Hannah Rigler
Spoken language unfolds over time. Consequently, there are brief periods of ambiguity, when incomplete input can match many possible words. Typical listeners solve this problem by immediately activating multiple candidates which compete for recognition. In two experiments using the visual world paradigm, we examined real-time lexical competition in prelingually deaf cochlear implant (CI) users, and normal hearing (NH) adults listening to severely degraded speech. In Experiment 1, adolescent CI users and NH controls matched spoken words to arrays of pictures including pictures of the target word and phonological competitors...
September 13, 2017: Cognition
https://www.readbyqxmd.com/read/28916961/practical-computational-toolkits-for-dendrimers-and-dendrons-structure-design
#5
Nuno Martinho, Liana C Silva, Helena F Florindo, Steve Brocchini, Teresa Barata, Mire Zloh
Dendrimers and dendrons offer an excellent platform for developing novel drug delivery systems and medicines. The rational design and further development of these repetitively branched systems are restricted by difficulties in scalable synthesis and structural determination, which can be overcome by judicious use of molecular modelling and molecular simulations. A major difficulty to utilise in silico studies to design dendrimers lies in the laborious generation of their structures. Current modelling tools utilise automated assembly of simpler dendrimers or the inefficient manual assembly of monomer precursors to generate more complicated dendrimer structures...
September 15, 2017: Journal of Computer-aided Molecular Design
https://www.readbyqxmd.com/read/28916864/sparticle-an-algorithm-for-the-analysis-of-filamentous-microorganisms-in-submerged-cultures
#6
Joost Willemse, Ferhat Büke, Dino van Dissel, Sanne Grevink, Dennis Claessen, Gilles P van Wezel
Streptomycetes are filamentous bacteria that produce a plethora of bioactive natural products and industrial enzymes. Their mycelial lifestyle typically results in high heterogeneity in bioreactors, with morphologies ranging from fragments and open mycelial mats to dense pellets. There is a strong correlation between morphology and production in submerged cultures, with small and open mycelia favouring enzyme production, while most antibiotics are produced mainly in pellets. Here we describe SParticle, a Streptomyces Particle analysis method that combines whole slide imaging with automated image analysis to characterize the morphology of submerged grown Streptomyces cultures...
September 15, 2017: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/28916508/development-of-a-whole-slide-imaging-system-on-smartphones-and-evaluation-with-frozen-section-samples
#7
Hong Yu, Feng Gao, Liren Jiang, Shuoxin Ma
BACKGROUND: The aim was to develop scalable Whole Slide Imaging (sWSI), a WSI system based on mainstream smartphones coupled with regular optical microscopes. This ultra-low-cost solution should offer diagnostic-ready imaging quality on par with standalone scanners, supporting both oil and dry objective lenses of different magnifications, and reasonably high throughput. These performance metrics should be evaluated by expert pathologists and match those of high-end scanners. OBJECTIVE: The aim was to develop scalable Whole Slide Imaging (sWSI), a whole slide imaging system based on smartphones coupled with optical microscopes...
September 15, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28916507/cardiac-patients-experiences-and-perceptions-of-social-media-mixed-methods-study
#8
Stephanie R Partridge, Anne C Grunseit, Patrick Gallagher, Becky Freeman, Blythe J O'Hara, Lis Neubeck, Sarah Due, Glenn Paull, Ding Ding, Adrian Bauman, Philayrath Phongsavan, Kellie Roach, Leonie Sadler, Helen Glinatsis, Robyn Gallagher
BACKGROUND: Traditional in-person cardiac rehabilitation has substantial benefits for cardiac patients, which are offset by poor attendance. The rapid increase in social media use in older adults provides an opportunity to reach patients who are eligible for cardiac rehabilitation but unable to attend traditional face-to-face groups. However, there is a paucity of research on cardiac patients' experiences and perspectives on using social media to support their health. OBJECTIVE: The aim of this study was to describe cardiac rehabilitation patients' experiences in using social media in general and their perspective on using social media, particularly Facebook, to support their cardiac health and secondary prevention efforts...
September 15, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28916243/feasibility-and-accuracy-of-automated-software-for-transthoracic-three-dimensional-left-ventricular-volume-and-function-analysis-comparisons-with-two-dimensional-echocardiography-three-dimensional-transthoracic-manual-method-and-cardiac-magnetic-resonance-imaging
#9
Gloria Tamborini, Concetta Piazzese, Roberto M Lang, Manuela Muratori, Elisa Chiorino, Massimo Mapelli, Laura Fusini, Sarah Ghulam Ali, Paola Gripari, Gianluca Pontone, Daniele Andreini, Mauro Pepi
BACKGROUND: Recently, a new automated software package (HeartModel) was developed to obtain three-dimensional (3D) left ventricular (LV) volumes using a model-based algorithm (MBA) with a "one-button" simple system and user-adjustable slider. The aims of this study were to verify the feasibility and accuracy of the MBA in comparison with other commonly used imaging techniques in a large unselected population, to evaluate possible accuracy improvements of free operator border adjustments or changes of the slider's default position, and to identify differences in method accuracy related to specific pathologies...
September 12, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28916160/-sociodemographic-and-health-related-determinants-of-health-care-utilisation-and-access-to-primary-and-specialist-care-results-of-a-nationwide-population-survey-in-germany-2006-2016
#10
Florian Tille, Bernhard Gibis, Klaus Balke, Adelheid Kuhlmey, Susanne Schnitzer
BACKGROUND: The aim of this paper is to identify systematic differences due to sociodemographic and health-related determinants in outpatient healthcare utilisation and access in Germany for the period from 2006 to 2016. The study focuses on frequent users and those reporting particularly long wait times for their physician appointments and contributes to assessing the level of health equity in Germany. METHODS: The investigation draws on nine population surveys conducted by the German National Association of Statutory Health Insurance Physicians (NASHIP), which interviewed 42,925 respondents aged 18 and above...
September 12, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28915822/what-hinders-the-uptake-of-computerized-decision-support-systems-in-hospitals-a-qualitative-study-and-framework-for-implementation
#11
Elisa G Liberati, Francesca Ruggiero, Laura Galuppo, Mara Gorli, Marien González-Lorenzo, Marco Maraldi, Pietro Ruggieri, Hernan Polo Friz, Giuseppe Scaratti, Koren H Kwag, Roberto Vespignani, Lorenzo Moja
BACKGROUND: Advanced Computerized Decision Support Systems (CDSSs) assist clinicians in their decision-making process, generating recommendations based on up-to-date scientific evidence. Although this technology has the potential to improve the quality of patient care, its mere provision does not guarantee uptake: even where CDSSs are available, clinicians often fail to adopt their recommendations. This study examines the barriers and facilitators to the uptake of an evidence-based CDSS as perceived by diverse health professionals in hospitals at different stages of CDSS adoption...
September 15, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28915502/to-stop-or-not-to-stop-contrasting-compliant-and-non-compliant-driver-behaviour-at-rural-rail-level-crossings
#12
Vanessa Beanland, Paul M Salmon, Ashleigh J Filtness, Michael G Lenné, Neville A Stanton
Many rail level crossings (RLXs) have only passive protection, such as static signs instructing road users to stop, yield, or look for trains. Stop signs have been suggested as a low-cost option to improve safety at passive RLXs, as requiring drivers to stop should encourage safe behaviour. However, field observations have noted high rates of non-compliance at stop-controlled RLXs. To explore this further, we conducted an on-road study to identify factors that influence compliance at stop-controlled RLXs. Twenty-two drivers drove a 30...
September 12, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28915478/studying-the-interactive-effects-of-menthol-and-nicotine-among-youth-an-examination-using-e-cigarettes
#13
Suchitra Krishnan-Sarin, Barry G Green, Grace Kong, Dana A Cavallo, Peter Jatlow, Ralitza Gueorguieva, Eugenia Buta, Stephanie S O'Malley
BACKGROUND: Tobacco products containing menthol are widely used by youth. We used e-cigarettes to conduct an experimental evaluation of the independent and interactive effects of menthol and nicotine among youth. PROCEDURES: Pilot chemosensory experiments with fourteen e-cigarette users identified low (barely perceptible, 0.5%) and high (similar to commercial e-liquid, 3.5%) menthol concentrations. Sixty e-cigarette users were randomized to a nicotine concentration (0mg/ml, 6mg/ml, 12mg/ml) and participated in 3 laboratory sessions...
August 31, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28912734/malm%C3%A3-treatment-referral-and-intervention-study-high-12-month-retention-rates-in-patients-referred-from-syringe-exchange-to-methadone-or-buprenorphine-naloxone-treatment
#14
Martin Bråbäck, Lars Ekström, Katja Troberg, Suzan Nilsson, Pernilla Isendahl, Louise Brådvik, Anders Håkansson
BACKGROUND: Heroin dependence is associated with high mortality. Opioid agonist treatment (OAT) with methadone or buprenorphine has strong evidence for treatment of this relapsing condition. In our setting, OAT has been associated with strict and demanding intake procedures, often with requirements of social stability, but also high, approximately 80 percent 12-month retention rates. In a recent randomized controlled trial, we demonstrated high rates of successful rapid referral from a syringe exchange programme (SEP) to treatment with methadone or buprenorphine, including actual treatment initiation...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28911999/living-systematic-reviews-4-living-guideline-recommendations
#15
Elie A Akl, Joerg J Meerpohl, Julian Elliott, Lara A Kahale, Holger J Schünemann
While it is important for the evidence supporting practice guidelines to be current, that is often not the case. The advent of living systematic reviews has made the concept of "living guidelines" realistic, with the promise to provide timely, up-to-date and high quality guidance to target users. We define living guidelines as an optimization of the guideline development process to allow updating individual recommendations as soon as new relevant evidence becomes available. A major implication of that definition is that the unit of update is the individual recommendation, and not the whole guideline...
September 1, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28911877/validity-and-reliability-of-naturalistic-driving-scene-categorization-judgments-from-crowdsourcing
#16
Christopher D D Cabrall, Zhenji Lu, Miltos Kyriakidis, Laura Manca, Chris Dijksterhuis, Riender Happee, Joost de Winter
A common challenge with processing naturalistic driving data is that humans may need to categorize great volumes of recorded visual information. By means of the online platform CrowdFlower, we investigated the potential of crowdsourcing to categorize driving scene features (i.e., presence of other road users, straight road segments, etc.) at greater scale than a single person or a small team of researchers would be capable of. In total, 200 workers from 46 different countries participated in 1.5days. Validity and reliability were examined, both with and without embedding researcher generated control questions via the CrowdFlower mechanism known as Gold Test Questions (GTQs)...
September 11, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28911330/extensive-transcriptomic-and-epigenomic-remodelling-occurs-during-arabidopsis-thaliana-germination
#17
Reena Narsai, Quentin Gouil, David Secco, Akanksha Srivastava, Yuliya V Karpievitch, Lim Chee Liew, Ryan Lister, Mathew G Lewsey, James Whelan
BACKGROUND: Seed germination involves progression from complete metabolic dormancy to a highly active, growing seedling. Many factors regulate germination and these interact extensively, forming a complex network of inputs that control the seed-to-seedling transition. Our understanding of the direct regulation of gene expression and the dynamic changes in the epigenome and small RNAs during germination is limited. The interactions between genome, transcriptome and epigenome must be revealed in order to identify the regulatory mechanisms that control seed germination...
September 15, 2017: Genome Biology
https://www.readbyqxmd.com/read/28910931/-quality-of-network-direct-reporting-of-information-about-intervention-service-in-population-at-high-risk-for-hiv-infection-in-china-2013-2014
#18
L Li, X B Cao, W Luo, C H Wang, Z Y Wu, K M Rou
Objective: To analyze the problems in the network direct reporting of information about intervention service conducted in population at high risk for HIV infection in China during 2013-2014, and provide evidence for the improvement of the network direct reporting of the intervention information. Methods: The wrong records of the intervention service in population at high-risk were collected from national AIDS prevention and treatment information system. The wrong records, including those found at county (district) level and those found at state level, were analyzed with descriptive statistical method...
September 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28910251/therapeutic-use-of-cannabis-prevalence-and-characteristics-among-adults-in-ontario-canada
#19
Hayley A Hamilton, Bruna Brands, Anca R Ialomiteanu, Robert E Mann
OBJECTIVE: To investigate the prevalence of therapeutic cannabis use within a general population sample of adults and to describe various characteristics associated with use. METHODS: Data were derived from the 2013 and 2014 CAMH Monitor Survey of adults in Ontario, Canada. This repeated cross-sectional survey employed a regionally stratified design and utilized computer-assisted telephone interviewing. Analyses were based on 401 respondents who reported using cannabis...
September 14, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28906127/cluster-headache-clinical-pattern-and-a-new-severity-scale-in-a-swedish-cohort
#20
Anna Steinberg, Carmen Fourier, Caroline Ran, Elisabet Waldenlind, Christina Sjöstrand, Andrea Carmine Belin
Background The aim of this study was to investigate clinical features of a cluster headache cohort in Sweden and to construct and test a new scale for grading severity. Methods Subjects were identified by screening medical records for the ICD 10 code G44.0, that is, cluster headache. Five hundred participating research subjects filled in a questionnaire including personal, demographic and medical aspects. We constructed a novel scale for grading cluster headache in this cohort: The Cluster Headache Severity Scale, which included number of attacks per day, attack and period duration...
January 1, 2017: Cephalalgia: An International Journal of Headache
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