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https://www.readbyqxmd.com/read/27936373/is-4-20-an-event-specific-marijuana-holiday-a-daily-diary-investigation-of-marijuana-use-and-consequences-among-college-students
#1
Adrian J Bravo, Matthew R Pearson, Bradley T Conner, Jamie E Parnes
OBJECTIVE: Given the popular association between April 20 ("4/20") and marijuana, the present study examined marijuana use and consequences on 4/20 compared with other days in order to test whether 4/20 is a high-risk, event-specific marijuana use holiday among college student marijuana users. METHOD: Fifty-nine college student marijuana users from three different, large U.S. universities located in Virginia, New Mexico, and Colorado completed daily brief surveys (<10 minutes) over a 12-day (April 15-April 26) period assessing prior-day marijuana use (i...
January 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/27936283/purity-adulteration-and-price-of-drugs-bought-online-versus-offline-in-the-netherlands
#2
Daan van der Gouwe, Tibor M Brunt, Margriet van Laar, Peggy van der Pol
BACKGROUND AND AIMS: Online drug markets flourish and consumers have high expectations of online quality and drug value. The aim of this study was to i) describe online drug purchases, and ii) compare online with offline purchased drugs regarding purity, adulteration and price. DESIGN: Comparison of lab analyses of 32,663 drug consumer samples (stimulants and hallucinogens) purchased between January 2013 and January 2016, of which 928 were bought online. SETTING: The Netherlands...
December 9, 2016: Addiction
https://www.readbyqxmd.com/read/27935681/continuous-optical-3d-printing-of-green-aliphatic-polyurethanes
#3
Sang-Hyun Pyo, Pengrui Wang, Wei Zhu, Henry Hwang, John Jamison Warner, Shaochen Chen
Photo-sensitive diurethanes were prepared from a green chemistry synthesis pathway based on methacrylate-functionalized six-membered cyclic carbonate and biogenic amines. A continuous optical 3D printing method for the diurethanes was developed to create user-defined gradient stiffness and smooth complex surface microstructures in seconds. The green chemistry-derived polyurethane (gPU) showed high optical transparency and we demonstrate the ability to tune the material stiffness of the printed structure along a gradient by controlling the exposure time and selecting various amine compounds...
December 9, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27935016/leveraging-constraints-and-biotelemetry-data-to-pinpoint-repetitively-used-spatial-features
#4
Brian M Brost, Mevin B Hooten, Robert J Small
Satellite telemetry devices collect valuable information concerning the sites visited by animals, including the location of central places like dens, nests, rookeries, or haul-outs. Existing methods for estimating the location of central places from telemetry data require user-specified thresholds and ignore common nuances like measurement error. We present a fully model-based approach for locating central places from telemetry data that accounts for multiple sources of uncertainty and uses all of the available locational data...
October 11, 2016: Ecology
https://www.readbyqxmd.com/read/27934356/improvements-to-the-practical-usability-of-the-crystalline-sponge-method-for-organic-structure-determination
#5
Greyson W Waldhart, Neal P Mankad, Bernard D Santarsiero
A microwell droplet approach provided high-quality samples in ≥90% yield of the "crystalline sponge", which was exhibited previously as a revolutionary organic structure determination method. The new protocol, from crystal growth to guest soaking, was conducted in 1-7 days (depending on the guest) and was robust toward user errors, marking improvements over existing protocols. Unit cell determination was used as a practical crystal screening metric. These advances improve the practicality of the crystalline sponge technique for characterizing unknown organic molecules...
December 2, 2016: Organic Letters
https://www.readbyqxmd.com/read/27933006/system-to-detect-racial-based-bullying-through-gamification
#6
José A Álvarez-Bermejo, Luis J Belmonte-Ureña, Africa Martos-Martínez, Ana B Barragán-Martín, María Del Mar Simón-Marquez
Prevention and detection of bullying due to racial stigma was studied in school contexts using a system designed following "gamification" principles and integrating less usual elements, such as social interaction, augmented reality and cell phones in educational scenarios. "Grounded Theory" and "User Centered Design" were employed to explore coexistence inside and outside the classroom in terms of preferences and distrust in several areas of action and social frameworks of activity, and to direct the development of a cell phone app for early detection of school bullying scenarios...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27932909/cigesmed-for-divers-establishing-a-citizen-science-initiative-for-the-mapping-and-monitoring-of-coralligenous-assemblages-in-the-mediterranean-sea
#7
Vasilis Gerovasileiou, Thanos Dailianis, Emmanouela Panteri, Nikitas Michalakis, Giulia Gatti, Maria Sini, Charalampos Dimitriadis, Yiannis Issaris, Maria Salomidi, Irene Filiopoulou, Alper Doğan, Laure Thierry de Ville d'Avray, Romain David, Melih Ertan Ҫinar, Drosos Koutsoubas, Jean-Pierre Féral, Christos Arvanitidis
BACKGROUND: Over the last decade, inventorying and monitoring of marine biodiversity has significantly benefited from the active engagement of volunteers. Although several Citizen Science projects concern tropical reef ecosystems worldwide, none of the existing initiatives has yet specifically focused on their Mediterranean equivalents. Mediterranean coralline reefs, known as "coralligenous", are bioherms primarily built by calcifying rhodophytes on hard substrates under dim-light conditions; they are considered hotspots of biodiversity and are extremely popular among divers due to their complex structure, conspicuous biological wealth and high aesthetic value...
2016: Biodiversity Data Journal
https://www.readbyqxmd.com/read/27932531/development-of-type-2-diabetes-mellitus-phenotyping-framework-using-expert-knowledge-and-machine-learning-approach
#8
Rina Kagawa, Yoshimasa Kawazoe, Yusuke Ida, Emiko Shinohara, Katsuya Tanaka, Takeshi Imai, Kazuhiko Ohe
BACKGROUND: Phenotyping is an automated technique that can be used to distinguish patients based on electronic health records. To improve the quality of medical care and advance type 2 diabetes mellitus (T2DM) research, the demand for T2DM phenotyping has been increasing. Some existing phenotyping algorithms are not sufficiently accurate for screening or identifying clinical research subjects. OBJECTIVE: We propose a practical phenotyping framework using both expert knowledge and a machine learning approach to develop 2 phenotyping algorithms: one is for screening; the other is for identifying research subjects...
December 7, 2016: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/27932514/long-term-therapy-with-wu-ling-san-a-popular-antilithic-chinese-herbal-formula-did-not-prevent-subsequent-stone-surgery-a-nationwide-population-based-cohort-study
#9
San-Yuan Wu, Huey-Yi Chen, Kao-Sung Tsai, Jen-Huai Chiang, Chih-Hsin Muo, Fung-Chang Sung, Yung-Hsiang Chen, Wen-Chi Chen
Traditional Chinese herbal medicine (CHM), which is widely used to treat pain and urolithiasis, is a promising therapy for urinary stone prevention. This study investigated the clinical efficacy of a popular CHM, Wu-Ling-San (WLS), in Taiwan for the prophylaxis of recurrent nephrolithiasis as assessed by surgical stone treatment via a nationwide population-based cohort study. The National Health Insurance Research Database, 2000-2010, which included one million patient records. All patients diagnosed with stone disease at the beginning of the study...
2016: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/27932400/grading-the-quality-of-evidence-in-complex-interventions-a-guide-for-evidence-based-practitioners
#10
M Hassan Murad, Jehad Almasri, Mouaz Alsawas, Wigdan Farah
Evidence-based practitioners who want to apply evidence from complex interventions to the care of their patients are often challenged by the difficulty of grading the quality of this evidence. Using the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach and an illustrative example, we propose a framework for evaluating the quality of evidence that depends on obtaining feedback from the evidence user (eg, guideline panel) to inform: (1) proper framing of the question, (2) judgements about directness and consistency of evidence and (3) the need for additional contextual and qualitative evidence...
December 8, 2016: Evidence-based Medicine
https://www.readbyqxmd.com/read/27931556/non-physician-health-workers-for-improving-adherence-to-medications-and-healthy-lifestyle-following-acute-coronary-syndrome-24-month-follow-up-study
#11
Krishna Kumar Sharma, Rajeev Gupta, Mukul Mathur, Vishnu Natani, Sailesh Lodha, Sanjeeb Roy, Denis Xavier
OBJECTIVE: To evaluate usefulness of non-physician health workers (NPHW) to improve adherence to medications and lifestyles following acute coronary syndrome (ACS). METHODS: We randomized 100 patients at hospital discharge following ACS to NPHW intervention (n=50) or standard care (n=50) in an open label study. NPHW was trained for interventions to improve adherence to medicines - antiplatelets, β-blockers, renin-angiotensin system (RAS) blockers and statins and healthy lifestyles...
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27931202/use-of-aids-for-smoking-cessation-and-alcohol-reduction-a-population-survey-of-adults-in-england
#12
Emma Beard, Jamie Brown, Susan Michie, Eileen Kaner, Petra Meier, Robert West
BACKGROUND: It is important for policy planning to chart the methods smokers and high-risk drinkers use to help them change their behaviour. This study assessed prevalence of use, and characteristics of users, of support for smoking cessation and alcohol reduction in England. METHODS: Data were used from the Smoking and Alcohol Toolkit Studies, which involve monthly face-to-face computer-assisted interviews of adults aged 16+ in England. We included data collected between June 2014 and July 2015 on 1600 smokers who had made at least one quit attempt and 911 high-risk drinkers (defined as scores >8+ on the full AUDIT or 5+ on questions 1-3 of the AUDIT-C) who had made an attempt to cut down in the past 12 months...
December 8, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27930941/evaluation-of-a-new-low-dose-levonorgestrel-intrauterine-contraceptive-system-over-5-years-of-use
#13
Kristina Gemzell-Danielsson, Dan Apter, Sylvia Dermout, Thomas Faustmann, Kimberly Rosen, Thomas Schmelter, Martin Merz, Anita Nelson
OBJECTIVE: To evaluate the efficacy and safety of a new, low-dose levonorgestrel intrauterine contraceptive system (LNG-IUS 12) for up to 5 years of use. STUDY DESIGN: In this Phase III study, 2885 nulliparous and parous women aged 18-35 years were randomized to LNG-IUS 8 or LNG-IUS 12 for 3 years. After 3 years, women using LNG-IUS 12 could continue for up to 2 additional years (5 years total). The primary outcome was occurrence of pregnancy (Pearl Index). Secondary outcomes included safety, bleeding, dysmenorrhea, discontinuations, and user satisfaction...
November 20, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27930807/exploring-flybase-data-using-quicksearch
#14
Steven J Marygold, Giulia Antonazzo, Helen Attrill, Marta Costa, Madeline A Crosby, Gilberto Dos Santos, Joshua L Goodman, L Sian Gramates, Beverley B Matthews, Alix J Rey, Jim Thurmond
FlyBase (flybase.org) is the primary online database of genetic, genomic, and functional information about Drosophila species, with a major focus on the model organism Drosophila melanogaster. The long and rich history of Drosophila research, combined with recent surges in genomic-scale and high-throughput technologies, mean that FlyBase now houses a huge quantity of data. Researchers need to be able to rapidly and intuitively query these data, and the QuickSearch tool has been designed to meet these needs...
December 8, 2016: Current Protocols in Bioinformatics
https://www.readbyqxmd.com/read/27930610/using-mhealth-for-hiv-tb-treatment-support-in-lesotho-enhancing-patient-provider-communication-in-the-start-study
#15
Yael Hirsch-Moverman, Amrita Daftary, Katharine A Yuengling, Suzue Saito, Moeketsi Ntoane, Koen Frederix, Llang B Maama, Andrea A Howard
BACKGROUND: mHealth is a promising means of supporting adherence to treatment. The Start TB patients on ART and Retain on Treatment (START) study included real-time adherence support using short-text messaging service (SMS) text messaging and trained village health workers (VHWs). We describe the use and acceptability of mHealth by patients with HIV/tuberculosis and health care providers. METHODS: Patients and treatment supporters received automated, coded medication and appointment reminders at their preferred time and frequency, using their own phones, and $3...
January 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27930590/low-mortality-but-increasing-incidence-of-staphylococcus-aureus-endocarditis-in-people-who-inject-drugs-experience-from-a-swedish-referral-hospital
#16
Hilmir Asgeirsson, Anders Thalme, Ola Weiland
Staphylococcus aureus is a leading cause of infective endocarditis in people who inject drugs (PWID). The management of S aureus endocarditis (SAE) in PWID can be problematic. The objective of this retrospective observational study was to assess the epidemiology, clinical characteristics, and mortality of S aureus endocarditis (SAE) in PWID in Stockholm, Sweden.The Department of Infectious Diseases at the Karolinska University Hospital serves as a regional referral center for drug users with severe infections...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27930328/estimating-uncertainty-in-respondent-driven-sampling-using-a-tree-bootstrap-method
#17
Aaron J Baraff, Tyler H McCormick, Adrian E Raftery
Respondent-driven sampling (RDS) is a network-based form of chain-referral sampling used to estimate attributes of populations that are difficult to access using standard survey tools. Although it has grown quickly in popularity since its introduction, the statistical properties of RDS estimates remain elusive. In particular, the sampling variability of these estimates has been shown to be much higher than previously acknowledged, and even methods designed to account for RDS result in misleadingly narrow confidence intervals...
December 7, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27929491/validation-of-an-improved-helical-diode-array-and-dose-reconstruction-software-using-tg-244-datasets-and-stringent-dose-comparison-criteria
#18
Saeed Ahmed, Benjamin Nelms, Jakub Kozelka, Geoffrey Zhang, Eduardo Moros, Vladimir Feygelman
The original helical ArcCHECK (AC) diode array and associated software for 3D measurement-guided dose reconstruction were characterized and validated; however, recent design changes to the AC required that the subject be revisited. The most important AC change starting in 2014 was a significant reduction in the overresponse of diodes to scattered radiation outside of the direct beam, accom-plished by reducing the amount of high-Z materials adjacent to the diodes. This change improved the diode measurement accuracy, but in the process invalidated the dose reconstruction models that were assembled based on measured data acquired with the older version of the AC...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27929443/enabling-sdn-in-vanets-what-is-the-impact-on-security
#19
Antonio Di Maio, Maria Rita Palattella, Ridha Soua, Luca Lamorte, Xavier Vilajosana, Jesus Alonso-Zarate, Thomas Engel
The demand for safe and secure journeys over roads and highways has been growing at a tremendous pace over recent decades. At the same time, the smart city paradigm has emerged to improve citizens' quality of life by developing the smart mobility concept. Vehicular Ad hoc NETworks (VANETs) are widely recognized to be instrumental in realizing such concept, by enabling appealing safety and infotainment services. Such networks come with their own set of challenges, which range from managing high node mobility to securing data and user privacy...
December 6, 2016: Sensors
https://www.readbyqxmd.com/read/27927733/participant-and-public-involvement-in-refining-a-peer-volunteering-active-aging-intervention-project-ace-active-connected-engaged
#20
Janet Withall, Janice L Thompson, Kenneth R Fox, Mark Davis, Selena Gray, Jolanthe de Koning, Liz Lloyd, Graham Parkhurst, Afroditi Stathi
BACKGROUND: Evidence for the health benefits of a physically active lifestyle among older adults is strong, yet only a small proportion of older people meet physical activity recommendations. A synthesis of evidence identified "best bet" approaches, and this study sought guidance from end-user representatives and stakeholders to refine one of these, a peer-volunteering active aging intervention. METHODS: Focus groups with 28 older adults and four professional volunteer managers were conducted...
December 7, 2016: Gerontologist
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