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polyhydramnios treatment

D Bockenhauer, Daniel G Bichet
PURPOSE OF REVIEW: In nephrogenic diabetes insipidus (NDI), the kidney is unable to concentrate urine despite elevated concentrations of the antidiuretic hormone arginine-vasopressin. In congenital NDI, polyuria and polydipsia are present from birth and should be immediately recognized to avoid severe episodes of dehydration. Unfortunately, NDI is still often recognized late after a 'diagnostic odyssey' involving false leads and dangerous treatments.Once diagnosed, appropriate treatment can be started...
April 2017: Current Opinion in Pediatrics
Huijing Zhang, Huixia Yang, Yu Sun, Lixin Fan, Xiaoxiao Zhang
The appearance of fetal urinoma is rare in prenatal care, especially when associated with polyhydramnions. Many previous reports have concluded that the visualization of a prenatal urinoma is probably a sign of underlying renal dysplasia or poor function. Thus, the management of the reported cases, conservative treatment or uniroma drainage, has not been unified. In this paper, we present two cases of prenatally detected urinoma with prenatal drainage to improve the prognosis.
February 2, 2017: Journal of Maternal-fetal & Neonatal Medicine
Delia Bogdanet, Aoife M Egan, Catriona Reddin, Oratile Kgosidialwa, Breda Kirwan, Louise Carmody, Fidelma P Dunne
Introduction: Approximately 40% of women with gestational diabetes mellitus (GDM) diagnosed using International Association of the Diabetes and Pregnancy Study Group (IADPSG) criteria require insulin therapy. Objective: We assessed whether the outcomes for women with GDM treated with insulin are comparable to women with normal glucose tolerance (NGT). Materials and Methods: This retrospective cohort study included 752 women with insulin-treated GDM and 2496 women with NGT during pregnancy...
March 1, 2017: Journal of Clinical Endocrinology and Metabolism
Levent Kebapcilar, Ayse Gul Kebapcilar, Tolgay Tuyan Ilhan, Suleyman Hilmi Ipekci, Suleyman Baldane, Aybike Pekin, Mustafa Kulaksizoglu, Cetin Celik
INTRODUCTION: Gestational diabetes is defined as various degrees of glucose intolerance diagnosed or detected for the first time during pregnancy and is the most common metabolic complication of pregnancy. Early diagnosis and adequate treatment are important to prevent complications. Pre-eclampsia, polyhydramnios, fetalmacrosomia, and operative delivery are some of the complications seen in pregnant women diagnosed with Gestational Diabetes Mellitus (GDM). AIM: The present study was designed to determine whether there was an association between Mean Platelet Volume (MPV) in predicting poor fetal outcome, insulin resistance, neonatal Apgar scores and gestational age for women with GDM...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
Mahin Najafian, Mojgan Barati, Sara Masihi, Ailin Fardipor
The aim of this study was to evaluate the effectiveness of metformin versus insulin in the glycemic control and to investigate the maternal and neonatal outcomes in in women with gestational diabetes mellitus. Pregnant women with gestational diabetes were randomized to either receive metformin (n=70) or insulin (n=70). Inclusion criteria were singleton pregnancy, following healthy diet and performing exercise for at least one week without satisfactory blood glucose level, no risk factor contributing to lactic acidosis, and no anatomic and/or chromosome anomalies...
September 28, 2016: Global Journal of Health Science
Nicholay A Shcherbina, Liudmyla A Vygovskaya
INTRODUCTION: the relevance of intrauterine infections is determined by significant peri- and postnatal loss as well as health impairment, which often results in disability and reduced quality of life. Ultrasonography is employed in order to provide a reliable assessment of the functional state of the fetoplacental system secondary to intrauterine fetal infection in the course of pregnancy. Ultrasound imaging is essential in diagnosis of various preclinical complications of pregnancy and detection of abnormalities in the developing fetus...
2016: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
Sung Hye Byun, So Young Lee, Seong Yeon Hong, Taeha Ryu, Baek Jin Kim, Jin Yong Jung
INTRODUCTION: In fetuses who are predicted to be at risk of catastrophic airway obstruction at delivery, the ex utero intrapartum treatment (EXIT) procedure is useful for securing the fetal airway while maintaining fetal oxygenation via placental circulation. Factors, including poor posture of the fetus and physician, narrow visual field, and issues of contamination in the aseptic surgical field, make fetal intubation during the EXIT procedure difficult. Herein, we report our experience of the usefulness of the GlideScope video laryngoscope (GVL) for intubation during the EXIT procedure...
September 2016: Medicine (Baltimore)
Kazuhiro Kajiwara, Tomohiro Tanemoto, Chie Nagata, Aikou Okamoto
Agnathia is a rare disease characterized by the absence of a mandible. Few cases of prenatally diagnosed isolated agnathia have been reported. We present a case report and review of the literature of prenatally diagnosed agnathia. A 38-year-old woman (gravida 0, para 0) was referred to our hospital at 28 weeks and 3 days of gestation for fetal evaluation because of polyhydramnios and suspected facial anomalies. Three-dimensional ultrasonography and MRI indicated agnathia. Premature rupture of the membranes occurred before the parents could reach a decision on the postnatal treatment...
2016: Case Reports in Obstetrics and Gynecology
Gabriele Tonni, Roberta Granese, Eduardo Félix Martins Santana, José Pedro Parise Filho, Isabela Bottura, Alberto Borges Peixoto, Annamaria Giacobbe, Andrea Azzerboni, Edward Araujo Júnior
AIM: The aim of this study was to review prenatally diagnosed tumors of the head and neck in the fetus and to report antenatal and postnatal outcomes. METHODS: PubMed/Medline, EMBASE/SCOPUS, Cochrane database and Google Scholar were reviewed over the last 20 years. No language or article type restriction was used. RESULTS: A total of 1940 record were retrieved. Of the 713 records screened, 566 full-text articles were assessed for eligibility...
February 1, 2017: Journal of Perinatal Medicine
Pietro Persiani, Filippo Maria Ranaldi, Lorena Martini, Anna Zambrano, Mauro Celli, Patrizia D'Eufemia, Ciro Villani
BACKGROUND: Osteogenesis imperfecta (OI) is a rare congenital genetic osteodystrophy, which has a prevalence of 1:20,000. OI is caused by the mutation of the COL1A1/COL1A2 genes, leading to a deficit of quality and/or quantity in the synthesis of procollagen-α type 1. Seven different forms of diverse clinical entity have been classified by Sillence and Glorieux, although, recently, up to 11 forms characterized by different genetic mutations have been recognized. Patients with OI suffer from extreme bone fragility and osteoporosis, which often predisposes them to frequent fractures...
August 2016: Medicine (Baltimore)
Jayesh P Thawani, Michael J Randazzo, Nickpreet Singh, Jared M Pisapia, Kalil G Abdullah, Phillip B Storm
Cervical teratomas are rare germ cell tumors affecting the fetus that are associated with significant morbidity and mortality due to an increased risk of airway obstruction at delivery. These tumors can commonly produce polyhydramnios that results from the fetus' impaired ability to swallow amniotic fluid. Improved rates of prenatal diagnosis through comprehensive evaluations and imaging have dramatically impacted the perinatal management of infants with this condition. Here, we report a patient diagnosed with polyhydramnios whose fetus was discovered to have a giant cervical teratoma on imaging studies...
July 2016: Journal of Neurological Surgery Reports
Lissa Fernandes Garcia Almeida, Edward Araujo Júnior, Gerson Claudio Crott, Marcos Masaru Okido, Aderson Tadeu Berezowski, Geraldo Duarte, Alessandra Cristina Marcolin
Objectives To identify the epidemiological risk factors for congenital anomalies (CAs) and the impact of these fetal malformations on the perinatal outcomes. Methods This prospective cohort study comprised 275 women whose fetuses had CAs. Maternal variables to establish potential risk factors for each group of CA and perinatal outcomes were evaluated. The primary outcome was CA. Secondary outcomes included: fetal growth restriction (FGR); fetal distress (FD); premature rupture of membranes (PROM); oligohydramnios or polyhydramnios; preterm delivery (PTD); stillbirth; cesarean section; low birth weight; Apgar score < 7 at the 1st and 5th minutes; need for assisted ventilation at birth; neonatal infection; need for surgical treatment; early neonatal death; and hospitalization time...
July 2016: Revista Brasileira de Ginecologia e Obstetrícia
Tarek Hamed Attia, Mohamed Maisara Abd Alhamed, Mohamed Fouad Selim, Mohamed Salah Haggag, Diaa Fathalla
Idiopathic arterial calcification of infancy is a rare autosomal recessive disease, characterized by deposition of calcium along the internal elastic membrane of arteries, accompanied by fibrous thickening of the intima which causes luminal narrowing. Here we are reporting a case of idiopathic arterial calcification of infancy in a Saudi female newborn of non-consanguineous pregnant woman who had polyhydramnios. The newborn baby had severe respiratory distress, systemic hypertension and persistent pulmonary hypertension of newborn...
November 2015: Journal of Radiology Case Reports
Rabia Akhtar, Mamoona Riffat, Zainab Mehmood
An epignathus is an extremely rare form of oropharyngeal teratoma that arises from the oral cavity, most commonly from the palate and is associated with a high mortality, secondary to airway obstruction in the neonatal period. We present a case of epignathus, diagnosed on antenatal ultrasound as teratoma. It was associated with polyhydramnios. The mother had presented with preterm labour at 27 weeks of gestation. Astillborn baby girl with a large epignathus was expelled spontaneously 2 hours after admission...
May 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Weimin Bi, Ian A Glass, Donna M Muzny, Richard A Gibbs, Christine M Eng, Yaping Yang, Angela Sun
Polyhydramnios, megalencephaly, and symptomatic epilepsy syndrome (PMSE) is an ultra rare neurodevelopmental disorder characterized by severe, infantile-onset intractable epilepsy, neurocognitive delay, macrocephaly, and craniofacial dysmorphism. The molecular diagnosis of this condition has thus far only been made in 16 Old Order Mennonite patients carrying a homozygous 7 kb founder deletion of exons 9-13 of STRADA. We performed clinical whole exome sequencing (WES) on a 4-year-old Indian male with global developmental delay, history of failure to thrive, infantile spasms, repetitive behaviors, hypotonia, low muscle mass, marked joint laxity, and dysmorphic facial features including tall forehead, long face, arched eyebrows, small chin, wide mouth, and tented upper lip...
August 2016: American Journal of Medical Genetics. Part A
Ebru Ersoy, Ali Ozgur Ersoy, Esra Yasar Celik, Aytekin Tokmak, Sibel Ozler, Yasemin Tasci
BACKGROUND: Striae gravidarum (SG), commonly called stretch marks, is an important cosmetic problem which is not treatable, although preventive measures might be effective. The aim of this study was to determine individual risk factors causing SG and the degree to which preventive measures could be effective. METHODS: This prospective observational study included 211 singleton primiparous pregnant women who were hospitalized for birth and who did not have systemic diseases or other risk factors, like drug use or polyhydramnios...
May 2016: Journal of the Chinese Medical Association: JCMA
Zbyněk Straňák, Ladislav Krofta, Lucia Anna Haak, Jiří Vojtěch, Luboš Hašlík, Michal Rygl, Karel Pýcha, Jaroslav Feyereisl
OBJECTIVES: Respiratory morbidity in congenital diaphragmatic hernia (CDH) is associated with high mortality and adverse outcome. Accurate prenatal diagnosis is essential for prognosis and potential treatment in utero. The aim was to evaluate the prenatal ultrasound findings in assessing the respiratory prognosis in fetuses with isolated left-sided CDH. METHODS: We retrospectively analyzed the medical records of 59 prenatally diagnosed left-sided CDH cases managed at a tertiary perinatal center...
January 2017: Journal of Maternal-fetal & Neonatal Medicine
Rachael T Overcash, Krishelle L Marc-Aurele, Andrew D Hull, Gladys A Ramos
A 27-year-old gravid 1 at 27 weeks 6 days with a history of hypothyroidism had an ultrasound that demonstrated a 3.9 × 3.2 × 3.3-cm well-circumscribed anterior neck mass, an extended fetal head, and polyhydramnios. Further characterization by magnetic resonance imaging (MRI) showed a fetal goiter. During her evaluation for the underlying cause of the fetal goiter, the patient revealed she was taking nutritional iodine supplements for treatment of her hypothyroidism. She was ingesting 62.5 times the recommended amount of daily iodine in pregnancy...
April 2016: Pediatrics
Cécile Guenot, Romaine Robyr, Nicole Jastrow, Yvan Vial, Luigi Raio, David Baud
Twin anemia-polycythemia sequence (TAPS) is a rare condition in monochorionic twin pregnancies. Small intertwin placental vascular communications allow transfusion, which results in a hemoglobin difference in the twins in the absence of oligohydramnios or polyhydramnios. We report here a case of TAPS diagnosed at 17 weeks' gestation in an obese patient (BMI 42) with a whole anterior placenta. The only possible treatment at this stage of pregnancy was intra-uterine transfusion (IUT), which was repeated weekly until photocoagulation of placental anastomoses was feasible...
April 2016: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
Zaigui Wu, Wensheng Hu
OBJECTIVES: The purpose of this study was to evaluate the clinical characteristics, imaging features, pregnancy complications, prenatal management of patients with placenta chorioangioma. METHODS: This was a retrospective study of 26 cases with histologically proven placenta chorioangima, in which the natural history, pregnancy complications, and clinical characteristics including ultrasonography were evaluated. RESULTS: Twelve of the twenty-six cases had a wide range of maternal-fetal complications including polyhydramnios (7), fetal growth restriction (3), fetal distress (2), pre-eclampsia (3), fetal anemia-thrombocytopenia (2), congestive heart failure (1) and fetal abnormality (1)...
April 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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