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Antenatal testing

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https://www.readbyqxmd.com/read/29223964/assessing-stakeholder-perceptions-of-the-acceptability-and-feasibility-of-national-scale-up-for-a-dual-hiv-syphilis-rapid-diagnostic-test-in-malawi
#1
Brandy L Peterson Maddox, Shauntā S Wright, Hazel Namadingo, Virginia B Bowen, Geoffrey A Chipungu, Mary L Kamb
OBJECTIVES: The WHO recommends pregnant women receive both HIV and syphilis testing at their first antenatal care visit, as untreated maternal infections can lead to severe, adverse pregnancy outcomes. One strategy for increasing testing for both HIV and syphilis is the use of point-of-care (rapid) diagnostic tests that are simple, proven effective and inexpensive. In Malawi, pregnant women routinely receive HIV testing, but only 10% are tested for syphilis at their first antenatal care visit...
December 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29221766/screening-for-fetal-growth-restriction-and-placental-insufficiency
#2
REVIEW
Melanie C Audette, John C Kingdom
Fetal growth restriction (FGR) continues to be a leading cause of preventable stillbirth and poor neurodevelopmental outcomes in offspring, and furthermore is strongly associated with the obstetrical complications of iatrogenic preterm birth and pre-eclampsia. The terms small for gestational age (SGA) and FGR have, for too long, been considered equivalent and therefore used interchangeably. However, the delivery of improved clinical outcomes requires that clinicians effectively distinguish fetuses that are pathologically growth-restricted from those that are constitutively small...
December 5, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29219937/relationship-between-maternal-characteristics-and-postpartum-hemorrhage-a-meta-analysis-study
#3
Aysegul Durmaz, Nuran Komurcu
BACKGROUND: Postpartum hemorrhage (PPH) is a leading cause of maternal death in low-income countries and the primary cause of approximately one of every four maternal deaths worldwide. PURPOSE: The aim of this study was to determine the antenatal risk factors of PPH and its effects. METHODS: The literature from nine databases was reviewed, and studies published between 2000 and 2012 were analyzed using terms such as "postpartum hemorrhage," "prevention of postpartum hemorrhage," and "management of postpartum hemorrhage...
December 6, 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/29212460/-the-co-authors-of-pregnancy-leveraging-men-s-sense-of-responsibility-and-other-factors-for-male-involvement-in-antenatal-services-in-kinshasa-drc
#4
Michelle M Gill, John Ditekemena, Aimé Loando, Vicky Ilunga, Marleen Temmerman, Franck Fwamba
BACKGROUND: Despite efforts to improve male involvement (MI), few male partners typically attend antenatal care (ANC). MI in ANC and interventions to prevent mother-to-child HIV transmission have been demonstrated to be beneficial for the HIV-positive mother and her child. This study aimed to explore factors influencing partner attendance and highlight interventions with potential to improve MI within a Congolese context. METHODS: This was an exploratory, qualitative study conducted in two urban and two semi-urban catchment areas of Kinshasa, DRC in June-September 2016...
December 6, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29209940/epidemiological-changes-in-rubella-igg-antibody-levels-detected-in-antenatal-women-from-a-retrospective-rubella-seroprevalence-study
#5
Ciara O'Connor, David Le Blanc, Richard J Drew
BACKGROUND: Rubella is caused by the rubella virus, a single-stranded RNA virus of the Togaviridae family. The most severe complications of rubella in adult women occur during pregnancy when infection can lead to miscarriage, stillbirth or congenital rubella syndrome. Antenatal rubella susceptibility screening is no longer performed in England, Scotland or Wales but continues in Northern Ireland. AIM: The aims of this seroprevalence study were to (1) determine amongst women presenting for antenatal care the percentage of women who are rubella susceptible, rubella immune and those with equivocal rubella antibody levels by year of birth and (2) to consider how rubella vaccination resources can best be utilised...
December 5, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29208587/hiv-surveillance-among-pregnant-women-attending-antenatal-clinics-evolution-and-current-direction
#6
Jacob Dee, Jesus M Garcia Calleja, Kimberly Marsh, Irum Zaidi, Christopher Murrill, Mahesh Swaminathan
Since the late 1980s, human immunodeficiency virus (HIV) sentinel serosurveillance among pregnant women attending select antenatal clinics (ANCs) based on unlinked anonymous testing (UAT) has provided invaluable information for tracking HIV prevalence and trends and informing global and national HIV models in most countries with generalized HIV epidemics. However, increased coverage of HIV testing, prevention of mother-to-child transmission (PMTCT), and antiretroviral therapy has heightened ethical concerns about UAT...
December 5, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/29207696/correlation-of-pregnancy-associated-plasma-protein-a-and-zinc-with-calculated-risk-ratio-of-dual-test
#7
Indranil Ghoshal, Bolar Suryakanth Varashree, Vijetha Shenoy Belle, Krishnananda Prabhu
Introduction: First trimester screening by dual test is the most preferred method of antenatal screening. The detection rate of foetal aneuploidy using dual test is 95%. This test uses maternal serum free β human Chorionic Gonadotropin (free β hCG) and Pregnancy Associated Plasma Protein A (PAPP-A) along with maternal demographic and foetal sonographic indices to calculate risk for foetal aneuploidy. PAPP-A is a zinc binding metalloproteinase which is also responsible for placental development and foetal growth...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29202747/seroprevalence-of-toxoplasmosis-and-risk-factors-of-toxoplasma-gondii-infection-among-pregnant-women-in-sri-lanka-a-cross-sectional-study
#8
Devika Iddawela, Sanura Malinda Pallegoda Vithana, Chathura Ratnayake
BACKGROUND: Toxoplasma gondii is an intracellular protozoan infecting humans and animals. Infection in adults usually causes mild disease but greater importance lies in preventing transplacental transmission which can cause major foetal anomalies and is vital to identify infection in pregnancy. Research on this regard in Sri Lanka is scarce and would be beneficial in developing antenatal care strategies for improved foetal outcome. METHODS: A random sample of 536 pregnant women attending antenatal care in Teaching Hospital Peradeniya from 2010 to 2013 was recruited for this study...
December 4, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29201921/selective-screening-strategies-for-gestational-diabetes-a-prospective-cohort-observational-study
#9
Sumaiya Adam, Paul Rheeder
Aim: We aimed to develop a prediction model for the diagnosis of gestational diabetes and to evaluate the performance of published prediction tools on our population. Methods: We conducted a cohort study on nondiabetic women < 26 weeks gestation at a level 1 clinic in Johannesburg, South Africa. At recruitment, participants completed a questionnaire and random basal glucose and HbA1c were evaluated. A 75 g 2-hour OGTT was scheduled between 24-28 weeks gestation, as per FIGO guidelines...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/29201460/early-diagnosis-of-hiv-among-infants-born-to-hiv-positive-mothers-on-option-b-plus-in-kampala-uganda
#10
Jonathan Izudi, Sylvia Auma, John Bosco Alege
Introduction: Globally, there is delay in accessing early HIV diagnosis (EID) among HIV exposed infants (HEIs). With paucity of data on EID use at Kisenyi Health Center, this study assessed factors associated with EID use among HEIs (HIV exposed infants). Method: This was a cross-sectional study of 246 HIV-positive mother-baby pairs. Data was collected by structured questionnaire, double-entered in EpiData, and analyzed with STATA using multinomial logistic regression at 5% significance level...
2017: AIDS Research and Treatment
https://www.readbyqxmd.com/read/29200892/trends-and-drivers-of-skilled-birth-attendant-use-in-nigeria-1990-2013-policy-implications-for-child-and-maternal-health
#11
Adeniyi F Fagbamigbe, Elizabeth O Hurricane-Ike, Oyindamola B Yusuf, Erhabor S Idemudia
Introduction: While Nigeria accounts for only 2% of the world population, it regrettably shares 14% of global maternal death burden. Whether its reported increase in antenatal care utilization is accompanied by increased use of skilled birth attendants (SBAs) is not known. This study assessed trends in utilization of SBAs in Nigeria between 1990 and 2013 and identified its determinants. Methods: Data from four consecutive Nigerian Demographic and Health Survey reports between 1990 and 2013 were pooled...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/29199913/elimination-of-mother-to-child-transmission-of-syphilis-is-it-a-reality-in-nigeria-by-2020
#12
Daniel A Adeyinka, Babayemi O Olakunde, Chamberline E Ozigbu, Emmanuel A Agogo, Mercy Morka, Temitope Atoba, Chris Obanubi, Gideon Okorie, Abiola Davies, Olanrewaju Oladimeji
BACKGROUND: Congenital syphilis is a global health problem, yet it has received little attention in recent years. Despite cost-effective syphilis screening and treatment, it continues to contribute hugely to perinatal morbidity and mortality worldwide. AIMS: To determine the prevalence and treatment coverage trend for syphilis among pregnant women in the national prevention of mother-to-child transmission programme in Nigeria and to evaluate progress towards the elimination of congenital syphilis in the country...
December 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/29199100/universal-test-and-treat-and-the-hiv-epidemic-in-rural-south-africa-a-phase-4-open-label-community-cluster-randomised-trial
#13
Collins C Iwuji, Joanna Orne-Gliemann, Joseph Larmarange, Eric Balestre, Rodolphe Thiebaut, Frank Tanser, Nonhlanhla Okesola, Thembisa Makowa, Jaco Dreyer, Kobus Herbst, Nuala McGrath, Till Bärnighausen, Sylvie Boyer, Tulio De Oliveira, Claire Rekacewicz, Brigitte Bazin, Marie-Louise Newell, Deenan Pillay, François Dabis
BACKGROUND: Universal antiretroviral therapy (ART), as per the 2015 WHO recommendations, might reduce population HIV incidence. We investigated the effect of universal test and treat on HIV acquisition at population level in a high prevalence rural region of South Africa. METHODS: We did a phase 4, open-label, cluster randomised trial of 22 communities in rural KwaZulu-Natal, South Africa. We included individuals residing in the communities who were aged 16 years or older...
November 30, 2017: Lancet HIV
https://www.readbyqxmd.com/read/29198182/improving-the-coverage-of-prevention-of-mother-to-child-transmission-of-hiv-services-in-nigeria-should-traditional-birth-attendants-be-engaged
#14
Babayemi O Olakunde, Sabastine Wakdok, Yewande Olaifa, Francis Agbo, Uduak Essen, Mathews Ojo, Maria Oke, Sarah Ibi
Traditional birth attendants (TBAs) play an important role in the provision of care to pregnant women in rural parts of Nigeria, but they are barely engaged by the formal healthcare system in expanding the low coverage of prevention of mother-to-child transmission of HIV (PMTCT) services. Using a systematic approach, we engaged TBAs in Abia and Taraba States to scale-up PMTCT services under the National Agency for Control of AIDS Comprehensive AIDS Program with States. We conducted mapping of the TBAs, built their capacities, obtained their buy-in on mobilization of their clients and other pregnant women for HIV testing service outreaches, and established referral and linkage systems...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29181452/prevalences-of-inherited-red-blood-cell-disorders-in-pregnant-women-of-different-ethnicities-living-along-the-thailand-myanmar-border
#15
Germana Bancone, Mary Ellen Gilder, Nongnud Chowwiwat, Gornpan Gornsawun, Elsi Win, Win Win Cho, Eh Moo, Aung Myat Min, Prakaykaew Charunwatthana, Verena I Carrara, Nicholas J White, Francois Nosten, Rose McGready
Background: Inherited red blood cell disorders are prevalent in populations living in malaria endemic areas; G6PD deficiency is associated with oxidant-induced haemolysis and abnormal haemoglobin variants may cause chronic anaemia. In pregnant women, microcytic anaemia caused by haemoglobinopathies mimics iron deficiency, complicating diagnosis and treatment. Anaemia during pregnancy is associated with morbidity and mortality. The aim of this study was to characterise the prevalence of G6PD deficiency and haemoglobinopathies  among the pregnant population living along the Thailand-Myanmar border...
2017: Wellcome Open Research
https://www.readbyqxmd.com/read/29181226/blood-safety-status-in-who-african-region-countries-lessons-learnt-from-mauritius
#16
André Loua, Janaki Sonoo, Laurent Musango, Jean Baptiste Nikiema, Thomas Lapnet-Moustapha
In 2001, the WHO Office for Africa adopted a strategy for blood safety defining four targets. This paper describes the progress made by Mauritius in the implementation of this strategy. The blood safety indicators were collected and compared with the norms recommended by WHO. The country has formulated its blood policy and developed a strategic plan for its implementation since 2004. The total number of blood donations increased from 31,228 in 2002 to 43,742 in 2016, giving an annual blood collection rate evolving from 26...
2017: Journal of Blood Transfusion
https://www.readbyqxmd.com/read/29178852/couples-hiv-counselling-and-couple-relationships-in-india-georgia-and-the-dominican-republic
#17
Thierry Tiendrebeogo, Melanie Plazy, Shrinivas Darak, Marija Miric, Eddy Perez-Then, Maia Butsashvili, Patrice Tchendjou, François Dabis, Joanna Orne-Gliemann
BACKGROUND: Couples HIV counseling and testing is essential for combination HIV prevention, but its uptake remains very low. We aimed to evaluate factors associated with couples HIV counseling uptake in India, Georgia and the Dominican Republic, as part of the ANRS 12127 Prenahtest intervention trial. METHODS: Pregnant women ≥15 years, attending their first antenatal care (ANC) session between March and September 2009, self-reporting a stable partner, and having received couple-oriented post-test HIV counseling (trial intervention) were included...
November 25, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29177365/gender-specific-reference-charts-of-fetal-head-circumference-in-a-singaporean-population
#18
George Sh Yeo, Maili Qi, Ruochen Du, Padma Lata Mahavadi, Chee Fu Yung, Koh Cheng Thoon, Edwin Wh Thia, Kai Lit Tan, Fon Min Lai, Nicole Kl Lee
INTRODUCTION: With the global outbreak of Zika virus and its association with microcephaly, an up-to-date fetal head circumference (HC) nomogram is crucial to offer a reference standard in order to make an accurate diagnosis. This study was conducted to revise the local fetal HC nomogram. MATERIALS AND METHODS: In this retrospective study, ultrasound data was used for construction of the fetal HC nomogram from a total of 6155 pregnancies in the ethnic Chinese population with low risk profile at KK Women's and Children's Hospital over a 10-year period...
October 2017: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/29174520/liver-dysfunction-during-pregnancy-and-its-association-of-with-preterm-birth-in-china-a-prospective-cohort-study
#19
Xun Zhuang, Ai-Min Cui, Qin Wang, Xiao-Yan Cheng, Yi Shen, Wei-Hua Cai, Hai-Bo Li, Sheng Zhang, Gang Qin
BACKGROUND: Liver dysfunction is common in pregnancy but its association with adverse pregnancy outcomes such as preterm birth (PTB) remains unclear. METHODS: A prospective cohort of HBV-infected or uninfected pregnant women attending antenatal care was recruited at Nantong Maternal and Child Health Hospital between January 1, 2012, and June 30, 2016. Liver function tests (LFTs) were monitored through pregnancy. The primary outcomes were PTB and very PTB (delivery prior 37 and 32weeks' gestation respectively)...
November 21, 2017: EBioMedicine
https://www.readbyqxmd.com/read/29166489/prevalence-of-syphilis-and-hiv-infection-during-pregnancy-in-incarcerated-women-and-the-incidence-of-congenital-syphilis-in-births-in-prison-in-brazil
#20
Rosa Maria Soares Madeira Domingues, Maria do Carmo Leal, Ana Paula Esteves Pereira, Barbara Ayres, Alexandra Roma Sánchez, Bernard Larouzé
This study aimed to estimate the prevalence of syphilis and HIV infection during pregnancy, the mother to child transmission of syphilis and the incidence of congenital syphilis in incarcerated women in Brazil; to compare these rates to those observed in pregnant women outside of jail; and to verify the maternal factors associated with syphilis infection during pregnancy in free and incarcerated women. We used data from two nationwide studies conducted during the period 2011-2014. The Birth in Brazil study included 23,894 free women cared for in 266 hospitals...
November 21, 2017: Cadernos de Saúde Pública
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