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Antenatal testing

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https://www.readbyqxmd.com/read/28209493/quantitative-analysis-of-fetal-facial-morphology-using-3d-ultrasound-and-statistical-shape-modelling-a-feasibility-study
#1
Andrea Dall'Asta, Silvia Schievano, Jan L Bruse, Gowrishankar Paramasivam, Christine Tita Kaihura, David Dunaway, Christoph C Lees
BACKGROUND: The antenatal detection of facial dysmorphism using three-dimensional ultrasound may raise the suspicion of an underlying genetic conditions but infrequently leads to a definitive antenatal diagnosis. Despite advances in array and non invasive prenatal testing, not all genetic conditions can be ascertained from such testing. OBJECTIVES: The aim of this study was to investigate the feasibility of quantitative assessment of fetal face features using prenatal three-dimensional ultrasound volumes and statistical shape modelling...
February 13, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28209187/perceptions-and-experiences-of-pregnant-women-about-routine-hiv-testing-and-counselling-in-ghimbi-town-ethiopia-a-qualitative-study
#2
Israel Mitiku, Adamu Addissie, Mitike Molla
BACKGROUND: Ethiopia has implemented routine HIV testing and counselling using a provider initiated HIV testing ('opt-out' approach) to achieve high coverage of testing and prevention of mother-to-child transmission of HIV. However, women's perceptions and experiences with this approach have not been well studied. We conducted a qualitative study to explore pregnant women's perceptions and experiences of routine HIV testing and counselling in Ghimbi town, Ethiopia, in May 2013. In-depth interviews were held with 28 women tested for HIV at antenatal clinics (ANC), as well as four health workers involved in routine HIV testing and counselling...
February 16, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28207948/right-sided-aortic-arch-in-the-age-of-microarray
#3
Edward F O'Mahony, Darren P Hutchinson, George McGillivray, Debbie L Nisbet, Ricardo Palma-Dias
OBJECTIVE: For fetuses with a diagnosis of right aortic arch and normal cardiac anatomy we aimed to establish the frequency of chromosomal anomaly diagnosed with SNP microarray analysis, particularly focusing on microduplications or microdeletions which would have gone undetected by conventional karyotyping and 6 probe fish (13,18,21, X,Y, TUPLE). METHOD: Retrospective study of fetal ultrasounds between 2011 and 2016 in an Australian tertiary referral centre. Outcomes of interest were survival and postnatal surgery for vascular ring...
February 16, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28207337/engaging-human-rights-in-the-response-to-the-evolving-zika-virus-epidemic
#4
Jennifer J K Rasanathan, Sarah MacCarthy, Debora Diniz, Els Torreele, Sofia Gruskin
In late 2015, an increase in the number of infants born with microcephaly in poor communities in northeast Brazil prompted investigation of antenatal Zika infection as the cause. Zika now circulates in 69 countries, and has affected pregnancies of women in 29 countries. Public health officials, policymakers, and international organizations are considering interventions to address health consequences of the Zika epidemic. To date, public health responses have focused on mosquito vector eradication, sexual and reproductive health services, knowledge and technology including diagnostic test and vaccine development, and health system preparedness...
February 16, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28206709/women-who-choose-cfdna-testing-should-not-be-denied-1-st-trimester-anatomy-scan
#5
Zarko Alfirevic, Catia M Bilardo, Laurent J Salomon, Ann Tabor
It is important to acknowledge that modern antenatal care includes a variety of screening programmes. Each of them should be evaluated in their own right and, when clinical effectiveness is proven, integrated in the antenatal care in the most cost-effective fashion. Screening for common aneuploidies and fetal anomalies are two such programmes which are routinely offered world-wide. Both screening programmes include components that interact with each other which leads to a considerable confusion in the debate about their evaluation and implementation...
February 16, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28199996/importance-of-timing-first-trimester-placental-growth-factor-and-use-of-serial-first-trimester-placental-growth-factor-measurements-in-screening-for-preeclampsia
#6
Beatrice Mosimann, Sofia Amylidi-Mohr, Katrin Höland, Daniel Surbek, Lorenz Risch, Luigi Raio
OBJECTIVE: The aims of this study were to test whether the performance of first-trimester placental growth factor (PlGF) in screening for preterm preeclampsia (PE) is gestational age dependent and to assess the value of serial first-trimester PlGF measurements in discriminating women at risk for PE. METHODS: PlGF was measured in women with singleton pregnancies at their first antenatal visit at 8+0 to 10+6 and additionally at 11+0 to 14+0 weeks of gestation. The difference in absolute values of serial PlGF measurements was expressed as Δ-PlGF...
February 16, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28199918/factors-associated-with-alcohol-use-prior-to-and-during-pregnancy-among-hiv-infected-pregnant-women-in-cape-town-south-africa
#7
Kirsty Brittain, Robert H Remien, Tamsin Phillips, Allison Zerbe, Elaine J Abrams, Landon Myer, Claude A Mellins
INTRODUCTION: Alcohol use during pregnancy is prevalent in South Africa, but there are few prospectively-collected data exploring patterns of consumption among HIV-infected women, which may be important to improve maternal and child health outcomes. We examined patterns of and factors associated with alcohol use prior to and during pregnancy among HIV-infected pregnant women in Cape Town, South Africa. METHODS: Participants were enrolled when entering antenatal care at a large primary care clinic, and alcohol use was assessed using the AUDIT (Alcohol Use Disorders Identification Test)...
January 31, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28188612/hepatitis-b-immunoglobulin-during-pregnancy-for-prevention-of-mother-to-child-transmission-of-hepatitis-b-virus
#8
REVIEW
Ahizechukwu C Eke, George U Eleje, Uzoamaka A Eke, Yun Xia, Jiao Liu
BACKGROUND: Hepatitis is a viral infection of the liver. It is mainly transmitted between people through contact with infected blood, frequently from mother to baby in-utero. Hepatitis B poses significant risk to the fetus and up to 85% of infants infected by their mothers at birth develop chronic hepatitis B virus (HBV) infection. Hepatitis B immunoglobulin (HBIG) is a purified solution of human immunoglobulin that could be administered to the mother, newborn, or both. HBIG offers protection against HBV infection when administered to pregnant women who test positive for hepatitis B envelope antigen (HBeAg) or hepatitis B surface antigen (HBsAg), or both...
February 11, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28181013/factors-associated-with-receiving-late-hiv-testing-among-women-delivering-at-hung-vuong-hospital-ho-chi-minh-city-vietnam-2014
#9
V N Khuu, V T Nguyen, N K Hills, T P Hau, D P Nguyen, V T Nhung, P T Lan, D B Brickley
HIV testing during pregnancy facilitates timely antiretroviral treatment for HIV-positive women. This study identifies reasons for late HIV testing among pregnant women delivering at a hospital in Ho Chi Minh City. We conducted a case-control study in which 160 cases were women who were tested for HIV late (i.e., at labor and delivery) and 160 controls were women who were tested during antenatal care (ANC). In multivariable logistic regression analysis, six variables were associated with late HIV testing: age less than 30 years, nine or fewer years of education, working as a homemaker or worker/farmer, living 20 km or more from the hospital, having received ANC at a private clinic/hospital only, and not believing that HIV testing is important during pregnancy...
February 8, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28180012/seroprevalence-and-co-infection-of-human-immunodeficiency-virus-hiv-and-herpes-simplex-virus-hsv-among-pregnant-women-in-lokoja-north-central-nigeria
#10
Olatunji Matthew Kolawole, Oluwatomi Olufunke Amuda, Charles Nzurumike, Muhammed Mustapha Suleiman, Jeremiah Ikhevha Ogah
BACKGROUND: Herpes simplex virus 1 (HSV-1) is normally associated with orofacial (orolabial) infections and encephalitis, whereas HSV-2 usually causes genital infections and can be transmitted from infected mothers to neonates. The evidence suggesting that HSV is facilitating the spread of the global human immunodeficiency virus (HIV) epidemic and the risk posed by these synergies to neonates in developing countries informed this study. OBJECTIVES: To determine the seroprevalence and co-infection of HIV and HSV, as well as their associated risk factors, in Lokoja, Nigeria...
October 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28176034/patient-satisfaction-with-virtual-obstetric-care
#11
Bethann Mangel Pflugeisen, Jin Mou
Introduction The importance of patient satisfaction in US healthcare is increasing, in tandem with the advent of new patient care modalities, including virtual care. The purpose of this study was to compare the satisfaction of obstetric patients who received one-third of their antenatal visits in videoconference ("Virtual-care") compared to those who received 12-14 face-to-face visits in-clinic with their physician/midwife ("Traditional-care"). Methods We developed a four-domain satisfaction questionnaire; Virtual-care patients were asked additional questions about technology...
February 7, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28169124/-therapeutic-mega-ureter-primitive-before-one-year-of-life-retrospective-study-of-20years
#12
B Picart, M Pons, A Line, C François, M-L Poli Merol
INTRODUCTION: What is the proper way to manage complicated primary mega-ureter in infants under the age of one. This has already been discussed in the literature but the controversy remains. OBJECTIVE: Evaluate the long-term results of the management of mega-ureter based support under the age of one. MATERIAL AND METHODS: Single-center retrospective study from 1990 to 2010. All children under one year found were evaluated including clinical examination, ultrasound, scintigraphy and cystography...
February 3, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28167254/seroprevalence-and-potential-risk-factors-of-t-gondii-infection-in-pregnant-women-attending-antenatal-care-at-bonga-hospital-southwestern-ethiopia
#13
Jalel Negero, Moti Yohannes, Kifle Woldemichael, Dechassa Tegegne
OBJECTIVES: To determine the seroprevalence and associated risk factors of T.gondii infection in pregnant women attending antenatal care at Bonga Hospital, Southwestern Ethiopia. METHODS: A cross-sectional study was carried out from February to May 2016. Systematic sampling technique was used to collect sera from 210 pregnant women. Sample was tested for anti-T. gondii antibodies by Latex Agglutination Test (LAT). Risk factors associated with T.gondii infection in pregnant women was assessed through structured questionnaire...
February 3, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28166698/partner-notification-and-treatment-for-sexually-transmitted-infections-among-pregnant-women-in-gaborone-botswana
#14
Ogechukwu A Offorjebe, Adriane Wynn, Neo Moshashane, Dvora Joseph Davey, Kaitlin Arena, Doreen Ramogola-Masire, Ponatshego Gaolebale, Chelsea Morroni, Jeffrey D Klausner
Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Trichomonas vaginalis (TV) are sexually transmitted infections (STIs) associated with adverse birth outcomes. Untreated partners contribute to high rates of STI reinfection; thus, partner notification and treatment remain important components of STI care and control. A prospective cohort study was conducted among 300 pregnant women presenting to the antenatal clinic at Princess Marina Hospital in Gaborone, Botswana who enrolled in an STI screening study...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28163842/assessment-of-maternal-knowledge-about-infantile-colic-in-saudi-arabia
#15
Hassan Al-Shehri, Bader H Al-Mogheer, Talal H Al-Sawyan, Abdulaziz Badr Abualalaa, Omar Ahmed Jarrah, Mosleh Jabari, Abdullah Al-Faris
INTRODUCTION: The infantile colic is a difficult experience met by parents in the first few months of an infant's life. This may lead to increased discomfort for infants as well as psychological distress for mothers. This study aimed at assessing the baseline knowledge of mothers in Saudi Arabia about infantile colic mainly in regard to the etiology and management. METHODS: In this cross-sectional study, a questionnaire was distributed among mothers in six primary healthcare centers (PHCC) in Riyadh, Saudi Arabia, during their visit for immunization clinics in 2016...
December 2016: Electronic Physician
https://www.readbyqxmd.com/read/28161191/laboratory-diagnosis-of-gestational-diabetes-an-in-silico-investigation-into-the-effects-of-pre-analytical-processing-on-the-diagnostic-sensitivity-and-specificity-of-the-oral-glucose-tolerance-test
#16
Erin Mansell, Helen Lunt, Paul Docherty
INTRODUCTION: Delayed separation of red cells from plasma causes pre analytical glucose loss, which in turn results in an under-diagnosis of GDM (gestational diabetes) based on the OGTT (oral glucose tolerance test). In silico investigations may help laboratory decision making, when exploring pragmatic improvements to sample processing. METHODS: Late pregnancy 0, 1 and 2h 75g OGTT values were obtained from two distinct populations of pregnant women: 1. Values derived from the HAPO (Hyperglycemia and Adverse Pregnancy Outcome) Study and 2...
February 2, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28148305/understanding-causal-pathways-within-health-systems-policy-evaluation-through-mediation-analysis-an-application-to-payment-for-performance-p4p-in-tanzania
#17
Laura Anselmi, Peter Binyaruka, Josephine Borghi
BACKGROUND: The evaluation of payment for performance (P4P) programmes has focused mainly on understanding contributions to health service coverage, without unpacking causal mechanisms. The overall aim of the paper is to test the causal pathways through which P4P schemes may (or may not) influence maternal care outcomes. METHODS: We used data from an evaluation of a P4P programme in Tanzania. Data were collected from a sample of 3000 women who delivered in the 12 months prior to interview and 200 health workers at 150 health facilities from seven intervention and four comparison districts in Tanzania in January 2012 and in February 2013...
February 2, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28148230/specialist-antenatal-clinics-for-women-at-high-risk-of-preterm-birth-a-systematic-review-of-qualitative-and-quantitative-research
#18
Reem Malouf, Maggie Redshaw
BACKGROUND: Preterm birth (PTB) is the leading cause of perinatal morbidity and mortality. Women with previous prenatal loss are at higher risk of preterm birth. A specialist antenatal clinic is considered as one approach to improve maternity and pregnancy outcomes. METHODS: A systematic review of quantitative, qualitative and mixed method studies conducted on women at high risk of preterm birth (PTB). The review primary outcomes were to report on the specialist antenatal clinics effect in preventing or reducing preterm birth, perinatal mortality and morbidity and women's perceptions and experiences of a specialist clinic whether compared or not compared with standard antenatal care...
February 2, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28144461/feasibility-reliability-and-validity-of-the-iranian-version-of-the-quality-of-life-questionnaire-for-pregnancy
#19
Mojgan Mirghafourvand, Sakineh Mohammad-Alizadeh-Charandabi, Mohammad Asghari Jafarabadi, Fatemeh Shiri, Solmaz Ghanbari-Homayi
BACKGROUND: Clinical studies are giving increased importance to quality of life assessments as measures of the relative effectiveness of prevention and treatment programs used during pregnancy and antenatally. OBJECTIVES: The aim of this study was to validate the Quality of life gravidarum (QOL-GRAV) questionnaire for Iranian women during the pregnant period. PATIENTS AND METHODS: In this cross-sectional methodological study, content validity following back and forward translation was assessed by a panel of experts...
September 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28141840/poor-quality-for-poor-women-inequities-in-the-quality-of-antenatal-and-delivery-care-in-kenya
#20
Jigyasa Sharma, Hannah H Leslie, Francis Kundu, Margaret E Kruk
BACKGROUND: Quality of healthcare is an important determinant of future progress in global health. However, the distributional aspects of quality of care have received inadequate attention. We assessed whether high quality maternal care is equitably distributed by (1) mapping the quality of maternal care in facilities located in poorer versus wealthier areas of Kenya; and (2) comparing the quality of maternal care available to Kenyans in and not in poverty. METHODS: We assessed three measures of maternal care quality: facility infrastructure and clinical quality of antenatal care and delivery care, using indicators from the 2010 Kenya Service Provision Assessment (SPA), a standardized facility survey with direct observation of maternal care provision...
2017: PloS One
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