keyword
https://read.qxmd.com/read/38327150/investigating-the-impact-on-long-term-outcomes-and-the-necessity-of-hereditary-thrombophilia-screening-in-presumed-or-perinatal-arterial-ischemic-stroke
#21
JOURNAL ARTICLE
Ömer Bektaş, Özben Akıncı Göktaş, Begüm Atasay, Serap Teber
This study aimed to investigate the influence of prothrombotic risk factors on long-term outcomes of patients with perinatal arterial ischemic stroke. The study was conducted through an analysis of monitoring results that were regularly maintained for approximately 20 years at a tertiary stroke-monitoring center. The study assessed prothrombotic risk factors, radiological area of involvement, clinical presentation, treatments, clinical outcomes, and long-term outcomes of the 48 patients included in the study, with a mean monitoring time of 77...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38304637/torch-toxoplasmosis-other-rubella-cytomegalovirus-herpes-simplex-virus-infection-and-the-enigma-of-anomalous-fetal-development-pregnancy-puzzles
#22
Nainita Patel, Kamlesh Chaudhari, Dharmesh J Patel, Jalormy S Joshi, Garapati Jyotsna
The cytomegalovirus (CMV), a common DNA virus with a high global seroprevalence, is the primary cause of teratogenic congenital infections, which presents a serious risk to public health. Maternal CMV infection is linked to congenital CMV (cCMV), a major contributor to non-genetic sensorineural hearing loss, cognitive developmental impairments, and cerebral palsy in infants. Transmission might occur through direct contact with infected bodily fluids, with higher transmission rates after primary infection and an increased risk of severe fetal effects before 20 weeks...
January 2024: Curēus
https://read.qxmd.com/read/38302917/strategies-for-addressing-the-needs-of-children-with-or-at-risk-of-developmental-disabilities-in-early-childhood-by-2030-a-systematic-umbrella-review
#23
JOURNAL ARTICLE
Tracey Smythe, Nathaniel Scherer, Carol Nanyunja, Cally J Tann, Bolajoko O Olusanya
BACKGROUND: There are over 53million children worldwide under five with developmental disabilities who require effective interventions to support their health and well-being. However, challenges in delivering interventions persist due to various barriers, particularly in low-income and middle-income countries. METHODS: We conducted a global systematic umbrella review to assess the evidence on prevention, early detection and rehabilitation interventions for child functioning outcomes related to developmental disabilities in children under 5 years...
February 2, 2024: BMC Medicine
https://read.qxmd.com/read/38278372/comorbidity-clusters-among-adults-with-cerebral-palsy-a-latent-class-analysis
#24
JOURNAL ARTICLE
Aleda M Leis, Edward A Hurvitz, Daniel G Whitney
INTRODUCTION: Adults with cerebral palsy (CP) are at risk for early multi-morbidity onset, but little is known about the composition of multi-morbidity profiles or how these profiles present across adulthood. The objective of this study was to identify multi-morbidity profiles and association with mortality among adults with CP. METHODS: This retrospective cohort study used a random 20% fee-for-service Medicare database from 01/01/2008-12/31/2019 from adults ≥18 years old with CP...
January 24, 2024: American Journal of Preventive Medicine
https://read.qxmd.com/read/38253913/histological-chorioamnionitis-and-pathological-stages-on-very-preterm-infant-outcomes
#25
JOURNAL ARTICLE
Jiajia Duan, Falin Xu, Chaoya Zhu, Ju Wang, Xiaoli Zhang, Yiran Xu, Bingbing Li, Xirui Peng, Jinjin Zhu, Xiaoyang Wang, Changlian Zhu
AIMS: Histological chorioamnionitis (HCA) is a condition linked to preterm birth and neonatal infection and its relationship with various pathological stages in extremely preterm neonates, and with their associated short- and long-term consequences, remains a subject of research. This study investigated the connection between different pathological stages of HCA and both short-term complications and long-term outcomes in preterm infants born at or before 32 weeks of gestational age...
January 22, 2024: Histopathology
https://read.qxmd.com/read/38246818/the-effect-of-structured-supportive-approach-based-on-kolcaba-s-comfort-theory-applied-to-parents-of-children-with-cerebral-palsy-on-child-s-comfort-quality-of-life-and-parent-s-self-efficacy-a-randomised-controlled-trial
#26
JOURNAL ARTICLE
Bircan Kahraman Berberoğlu, Hüsniye Çalişir
AIM: This study aims to assess how a structured supportive approach applied to the parents of children living with cerebral palsy according to how the Theory of Comfort affects the child's comfort, quality of life, and parent's self-efficacy. DESIGN: A single-blind, randomised, controlled experimental trial. METHODS: The study was conducted with parents of children with cerebral palsy aged between 8 and 16 years who presented to the rehabilitation centers between October 2021 and November 2022...
January 20, 2024: Journal of Pediatric Nursing
https://read.qxmd.com/read/38190242/adaptive-intervention-to-prevent-respiratory-illness-in-cerebral-palsy-protocol-for-a-feasibility-pilot-randomized-controlled-trial
#27
JOURNAL ARTICLE
Alyssa Fleischman, Carlos Lerner, Heidi Kloster, Paul Chung, Thomas Klitzner, Christopher Cushing, Danielle Gerber, Barbara Katz, Gemma Warner, Kristina Devi Singh-Verdeflor, Roxana Delgado-Martinez, Lorena Porras-Javier, Siem Ia, Teresa Wagner, Mary Ehlenbach, Ryan Coller
BACKGROUND: This study will pilot-test an innovative just-in-time adaptive intervention to reduce severe respiratory illness among children with severe cerebral palsy (CP). Our intervention program, Respiratory Exacerbation-Plans for Action and Care Transitions (RE-PACT), delivers timely customized action planning and rapid clinical response when hospitalization risk is elevated. OBJECTIVE: This study aims to establish RE-PACT's feasibility, acceptability, and fidelity in up to 90 children with severe CP...
January 8, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38133768/etiology-and-ontogeny-of-cerebral-palsy-implications-for-practice-and-research
#28
REVIEW
Mark I Evans, David W Britt, Lawrence D Devoe
Cerebral palsy (CP) has been recognized as a group of neurologic disorders with varying etiologies and ontogenies. While a percentage of CP cases arises during labor, the expanded use of electronic fetal monitoring (EFM) to include prevention of CP has resulted in decades of vastly increased interventions that have not significantly reduced the incidence of CP for infants born at term in the USA. Litigation alleging that poor obstetrical practice caused CP in most of these affected children has led to contentious arguments regarding the actual etiologies of this condition and often resulted in substantial monetary awards for plaintiffs...
December 22, 2023: Reproductive Sciences
https://read.qxmd.com/read/38111458/a-review-of-the-occurrence-of-intraventricular-hemorrhage-in-preterm-newborns-and-its-future-neurodevelopmental-consequences
#29
REVIEW
Gauri S Pande, Jayant D Vagha
Intraventricular hemorrhage (IVH) is a type of bleeding that occurs through the germinal matrix and comes through the ependymal cells into the ventricular cavity. It is mostly seen in preterm neonates but can also be seen sometimes in term neonates. Various factors predispose to preterm delivery; it can be spontaneous or medically induced. Spontaneous IVH occurs in cases of intrauterine infections in the mother, and it can be induced in cases of medical emergencies such as preeclampsia and eclampsia. The brain of a preterm newborn is not fully developed as it does not have pericytes and proteins, so it can bleed very quickly, which can cause IVH...
November 2023: Curēus
https://read.qxmd.com/read/38111136/neonatal-well-being-and-timing-of-brain-injury-in-persons-with-cerebral-palsy-born-at-term-or-late-preterm
#30
JOURNAL ARTICLE
Susan M Reid, Gina L Hinwood, Angela T Guzys, Rod W Hunt, Dinah S Reddihough
AIM: To describe the distribution of neuroimaging patterns in a term/late preterm population-based cohort with cerebral palsy (CP), ascertain associations between neuroimaging patterns and neonatal well-being, estimate the proportion with antenatal or perinatal timing of neuropathology, and apply this information to the understanding of common mechanisms of brain injury and causal pathways. METHOD: The cohort for this observational study comprised 1348 persons born between 1999 and 2017 in Victoria, Australia...
December 18, 2023: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/38094189/bone-health-in-children-with-severe-cerebral-palsy
#31
JOURNAL ARTICLE
Vincent Barbier, Vincent Goeb, Richard Gouron, Severine Fritot, Romuald Mentaverri, Céline Klein
AIM: To describe bone health and associated factors in children with severe cerebral palsy. METHOD: In a retrospective, single-centre study, we performed a comprehensive bone evaluation (including clinical, densitometric and bone biomarker assessments) of children with severe cerebral palsy. RESULTS: None of the 19 included children had a normal BMCTBLH Z score, and only one had a BMDTBLH Z score greater than -2. Six children had a BMDLS Z score greater than -2...
2023: Frontiers in Pediatrics
https://read.qxmd.com/read/38070889/latin-american-cerebral-palsy-register-latam-cpr-study-protocol-to-develop-a-collaborative-register-with-surveillance-of-children-with-cerebral-palsy-in-latin-american-countries
#32
JOURNAL ARTICLE
Maria de Las Mercedes Ruiz Brunner, Israt Jahan, Eduardo Cuestas, Maria Elisabeth Cieri, Johana Escobar Zuluaga, Ana Laura Condinanzi, Federico Sanchez, Sarah McIntyre, Hayley Smithers-Sheedy, Mohammad Muhit, Nadia Badawi, Raul Díaz, Agripina Diaz, Jorge Carranza, Claudia Durán, Carlos Alberto Quintero Valencia, Mariana Melaragno, Gulam Khandaker
INTRODUCTION: Cerebral palsy (CP) is one of the leading causes of childhood disability globally with a high burden in low-income and middle-income countries (LMICs). Preliminary findings from the global LMIC CP Register (GLM CPR) suggest that the majority of CP in LMICs are due to potentially preventable causes. Such data are lacking in the Latin American region. Generating comparable epidemiological data on CP from this region could enable translational research and services towards early diagnosis and early intervention...
December 9, 2023: BMJ Open
https://read.qxmd.com/read/38033771/association-between-bronchopulmonary-dysplasia-and-death-or-neurodevelopmental-impairment-at-3%C3%A2-years-in-preterm-infants-without-severe-brain-injury
#33
JOURNAL ARTICLE
Wenli Li, Yong Wang, Juan Song, Chen Zhang, Yiran Xu, Falin Xu, Xiaoyang Wang, Changlian Zhu
OBJECTIVE: We investigated the association between bronchopulmonary dysplasia (BPD) and 3 years death or neurodevelopmental impairment (NDI) in very preterm infants without severe brain injury. METHOD: Our prospective cohort study recruited preterm infants who were born prior to 32 weeks of gestational age and survived in the neonatal intensive care unit until 36 weeks of corrected age. Upon reaching 3 years of age, each infant was assessed for death or NDI such as cerebral palsy, cognitive deficit, hearing loss, and blindness...
2023: Frontiers in Neurology
https://read.qxmd.com/read/38027271/-pseudomonas-aeruginosa-in-children-with-cerebral-palsy-a-prospective-study
#34
JOURNAL ARTICLE
Katrien Romaen, Isabelle Van Ussel, Carolin Van Rossem, Sandra Kenis, Berten Ceulemans, Kim Van Hoorenbeeck, Stijn Verhulst
INTRODUCTION: Children with cerebral palsy (CP) often present with chronic respiratory symptoms. Pseudomonas aeruginosa (PA), is a known pathogen associated with more severe respiratory disease. Preventive actions to eradicate this bacterium and to improve the respiratory condition of children with CP could be very valuable. Therefore, we assessed the prevalence of PA and its association with respiratory disease. METHODS: Throat swabs were taken in children with CP, aged 0-18 years...
2023: Frontiers in Pediatrics
https://read.qxmd.com/read/38001232/application-of-3d-scanner-to-measure-physical-size-and-improvement-of-hip-brace-manufacturing-technology-in-severe-cerebral-palsy-patients
#35
JOURNAL ARTICLE
Jung-Min Kim, Jiwoon Lim, Sun-Young Choi, Sung-Han Rhim, Jaewon Beom, Ju Seok Ryu
This prospective pilot study aimed to develop a personalized hip brace for treating hip subluxation in children with cerebral palsy. Nineteen children, aged 1-15, with severe cerebral palsy participated in the study. Customized hip braces were created based on 3D scanner measurements and worn for 7 days. The primary outcome, Hip Migration Index (MI), and secondary outcomes, including range of motion (ROM) in the hip and knee joints, pain intensity, satisfaction, discomfort scores, CPCHILD, and wearability test, were assessed...
November 24, 2023: Scientific Reports
https://read.qxmd.com/read/37986125/validation-study-on-a-prediction-formula-to-estimate-the-weight-of-children-adolescents-with-special-needs-aged-2-18-years-old
#36
JOURNAL ARTICLE
Nurul Huda Ibrahim, Norasimah Kassim, Salimah Othman, Azahadi Omar, Norsuhaila Shaari, Anis Aslah Awiskarni, Norafidza Ashiquin Abdul Patah, Nabila Mohamed Nezuri, Maizatul Naqiah Zulfifli, Mohd Nadzrul Anuar Awang, Muhamad Farid Sani, Noorfadzlina Abdul Rashad, Siti Farhana Mesbah
BACKGROUND: This study aims to validate two predictive formulas of weight estimating strategies in children with special needs, namely the Cattermole formula and the Mercy formula. METHODOLOGY: A cross-sectional study with a universal sampling of children and adolescents with special needs aged 2-18 years old, diagnosed with cerebral palsy, down syndrome, autism and attention-deficit/hyperactivity disorder was conducted at Community-Based Rehabilitation in Central Zone Malaysia...
November 20, 2023: Journal of Health, Population, and Nutrition
https://read.qxmd.com/read/37979121/identifying-longer-term-health-events-and-outcomes-and-health-service-use-of-low-birthweight-cald-infants-in-australia
#37
JOURNAL ARTICLE
Shae Karger, Emmanuel U Ndayisaba, Joanne Enticott, Emily J Callander
INTRODUCTION: Approximately one-third of all births in Australia each year are by culturally and linguistically diverse (CALD) women. CALD women are at an increased risk of adverse pregnancy and birth outcomes including prematurity and low birthweight. Infants born weighing less than 2500 g are susceptible to increased risk of ill health and morbidities such as cognitive defects including cerebral palsy, and neuro-motor functioning. METHODS: An existing linked administrative dataset, Maternity 1000 was utilized for this study which has identified all children born in Queensland (QLD), Australia, between 1st July 2012 to 30th June 2018 from the QLD Perinatal Data Collection...
November 18, 2023: Maternal and Child Health Journal
https://read.qxmd.com/read/37978050/cerebral-venous-thrombosis-a-practical-review
#38
JOURNAL ARTICLE
Afshin Borhani-Haghighi, Etrat Hooshmandi
The evolution of the Coronavirus Disease-2019 pandemic and its vaccination raised more attention to cerebral venous thrombosis (CVT). Although CVT is less prevalent than arterial stroke, it results in larger years of life lost. CVT is more common in women and young patients. Predisposing factors are categorized as transient factors such as pregnancy, puerperium, oral contraceptive pills, trauma, and dehydration; and permanent factors such as neoplastic, vasculitic, thrombophilic, hematologic conditions, infectious causes such as severe acute respiratory syndrome coronavirus-2 infection and HIV...
January 21, 2024: Postgraduate Medical Journal
https://read.qxmd.com/read/37927486/arginase-deficiency-masked-by-cerebral-palsy-and-coagulopathy-three-varied-presentations-of-latin-american-origin
#39
Shelby L Mills, Paige Roberts, Myla Ashfaq, Kathryn Leal, Hope Northrup, Deborah L Brown, David Rodriguez-Buritica, Laura S Farach
Arginase deficiency (ARG1-D) is an autosomal recessive inborn error of metabolism that is often misdiagnosed. Classic presentation of ARG1-D includes progressive symptoms of spasticity, delayed development, cognitive impairment, protein avoidance, and seizures. Patients who present atypically may evade diagnosis and require a thoughtful diagnostic workup. Here, we discuss three females of Latin American origin with differing clinical presentations, but who all have the same intronic pathogenic variant in ARG1 ...
November 2023: JIMD Reports
https://read.qxmd.com/read/37905735/methylxanthine-for-the-prevention-and-treatment-of-apnea-in-preterm-infants
#40
REVIEW
Keri A Marques, Matteo Bruschettini, Charles C Roehr, Peter G Davis, Michelle Fiander, Roger Soll
BACKGROUND: Very preterm infants often require respiratory support and are therefore exposed to an increased risk of chronic lung disease and later neurodevelopmental disability. Although methylxanthines are widely used to prevent and treat apnea associated with prematurity and to facilitate extubation, there is uncertainty about the benefits and harms of different types of methylxanthines. OBJECTIVES: To assess the effects of methylxanthines on the incidence of apnea, death, neurodevelopmental disability, and other longer-term outcomes in preterm infants (1) at risk for or with apnea, or (2) undergoing extubation...
October 31, 2023: Cochrane Database of Systematic Reviews
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