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cerebral palsy prevention

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https://www.readbyqxmd.com/read/27921445/risk-of-neonatal-and-childhood-morbidity-among-preterm-infants-exposed-to-marijuana
#1
Sarah K Dotters-Katz, Marcela C Smid, Tracy A Manuck, Torri D Metz
BACKGROUND: Limited data exist regarding the neonatal and neurodevelopmental outcomes of infants exposed to marijuana (MJ) in-utero, particularly among preterm infants. We hypothesized that MJ-exposed preterm infants would have worse neonatal and childhood developmental outcomes compared to MJ-unexposed infants. METHODS: Secondary analysis of multicenter randomized-controlled trial of antenatal magnesium sulfate for prevention of cerebral palsy was conducted. Singleton non-anomalous infants delivered <35 weeks exposed to MJ in-utero were compared to MJ-unexposed...
December 6, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27916232/neuroinflammation-in-intrauterine-growth-restriction
#2
REVIEW
Julie A Wixey, Kirat K Chand, Paul B Colditz, S Tracey Bjorkman
Disruption to the maternal environment during pregnancy from events such as hypoxia, stress, toxins, inflammation, and reduced placental blood flow can affect fetal development. Intrauterine growth restriction (IUGR) is commonly caused by chronic placental insufficiency, interrupting supply of oxygen and nutrients to the fetus resulting in abnormal fetal growth. IUGR is a major cause of perinatal morbidity and mortality, occurring in approximately 5-10% of pregnancies. The fetal brain is particularly vulnerable in IUGR and there is an increased risk of long-term neurological disorders including cerebral palsy, epilepsy, learning difficulties, behavioural difficulties and psychiatric diagnoses...
November 25, 2016: Placenta
https://www.readbyqxmd.com/read/27900176/systematic-review-of-physical-activity-and-exercise-interventions-to-improve-health-fitness-and-well-being-of-children-and-young-people-who-use-wheelchairs
#3
Thomas D O'Brien, Jane Noyes, Llinos Haf Spencer, Hans-Peter Kubis, Richard P Hastings, Rhiannon Whitaker
AIM: To perform a systematic review establishing the current evidence base for physical activity and exercise interventions that promote health, fitness and well-being, rather than specific functional improvements, for children who use wheelchairs. DESIGN: A systematic review using a mixed methods design. DATA SOURCES: A wide range of databases, including Web of Science, PubMed, BMJ Best Practice, NHS EED, CINAHL, AMED, NICAN, PsychINFO, were searched for quantitative, qualitative and health economics evidence...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27893565/first-person-perspective-action-observation-training-in-individuals-with-parkinson-s-disease-a-consideration-of-concept-controlled-pilot-trial
#4
Giovanni Giorgi, Francesco Ferrarello, Francesca Merlo, Stefano Fumagalli, Niccolò Marchionni, Mauro Di Bari
BACKGROUND AND PURPOSE: Action observation training (AOT) consists of the observing of actions performed by others, followed by imitation. Physical therapy techniques based on action observation may influence motor performance in individuals with idiopathic Parkinson's disease (IPD). OBJECTIVES: The aim of this pilot study was to provide a preliminary approach to assess AOT in anatomical first-person perspective (FPP) as a rehabilitation technique to improve body function and activity in individuals with disability due to IPD...
November 23, 2016: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/27891365/visual-function-and-ocular-status-in-children-with-disabilities-in-special-schools-of-northern-india
#5
Gurvinder Kaur, Satish Thomas, Mahesh Jindal, S M Bhatti
INTRODUCTION: Children with disabilities (other than visual impairment) are at a higher risk of visual impairment as compared to normal population. Majority of the ocular disorders, like refractive errors and strabismus, are easily treatable. As these children depend on their visual inputs for social and academic activities, an early detection and prompt treatment of even a minor visual problem is of utmost importance for them. AIM: To assess the visual function and ocular status of children with disabilities other than visual impairment and to identify the preventable and treatable causes of visual impairment...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27861776/fatigue-and-its-relationship-with-physical-activity-age-and-body-composition-in-adults-with-cerebral-palsy
#6
Patrick G McPhee, Laura K Brunton, Brian W Timmons, Todd Bentley, Jan Willem Gorter
AIM: The objectives of this exploratory study were (1) to describe the experience of fatigue in adults with cerebral palsy (CP) inclusive of all levels of the Gross Motor Function Classification System (GMFCS); and (2) to determine if physical activity level, sedentary time, age, or body composition can predict fatigue in adults with CP. METHOD: An observational study was conducted in an outpatient setting in Ontario, Canada. Participants included adults with CP (n=41; GMFCS levels I-V; mean age 33...
November 14, 2016: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/27843239/unique-neuro-ophthalmic-presentation-of-gun-pellet-injury
#7
Reena Sharma, Sanjay Sharma, Swati Phuljhele, Rohit Saxena
We describe a unique case of orbital gunshot injury with isolated intraorbital pellets lodged symmetrically in the two apices, causing identical clinical presentation, and absence of any associated globe or cerebral injury. He developed bilateral complete third nerve palsy with bilateral traumatic optic neuropathy. The optic nerve strut prevented the pellets from going into the brain on both the sides.
September 2016: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/27822084/the-danish-cerebral-palsy-follow-up-program
#8
REVIEW
Helle Mätzke Rasmussen, Kirsten Nordbye-Nielsen, Bjarne Møller-Madsen, Mette Johansen, Niels Ellitsgaard, Charlotte Reinhardt Pedersen, Gija Rackauskaite, Henriette Engberg, Niels Wisbech Pedersen
AIM OF DATABASE: The Danish Cerebral Palsy Follow-up Program is a combined follow-up program and national clinical quality database that aims to monitor and improve the quality of health care for children with cerebral palsy (CP). STUDY POPULATION: The database includes children with CP aged 0-15 years and children with symptoms of CP aged 0-5 years. MAIN VARIABLES: In the follow-up program, the children are offered examinations throughout their childhood by orthopedic surgeons, physiotherapists, occupational therapists, and pediatricians...
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27802825/mog-igg-in-nmo-and-related-disorders-a-multicenter-study-of-50-patients-part-3-brainstem-involvement-frequency-presentation-and-outcome
#9
Sven Jarius, Ingo Kleiter, Klemens Ruprecht, Nasrin Asgari, Kalliopi Pitarokoili, Nadja Borisow, Martin W Hümmert, Corinna Trebst, Florence Pache, Alexander Winkelmann, Lena-Alexandra Beume, Marius Ringelstein, Oliver Stich, Orhan Aktas, Mirjam Korporal-Kuhnke, Alexander Schwarz, Carsten Lukas, Jürgen Haas, Kai Fechner, Mathias Buttmann, Judith Bellmann-Strobl, Hanna Zimmermann, Alexander U Brandt, Diego Franciotta, Kathrin Schanda, Friedemann Paul, Markus Reindl, Brigitte Wildemann
BACKGROUND: Myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) are present in a subset of aquaporin-4 (AQP4)-IgG-negative patients with optic neuritis (ON) and/or myelitis. Little is known so far about brainstem involvement in MOG-IgG-positive patients. OBJECTIVE: To investigate the frequency, clinical and paraclinical features, course, outcome, and prognostic implications of brainstem involvement in MOG-IgG-positive ON and/or myelitis. METHODS: Retrospective case study...
November 1, 2016: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/27789461/hypopituitarism-in-children-with-cerebral-palsy
#10
REVIEW
Suma Uday, Nick Shaw, Ruth Krone, Jeremy Kirk
Poor growth and delayed puberty in children with cerebral palsy is frequently felt to be related to malnutrition. Although growth hormone deficiency is commonly described in these children, multiple pituitary hormone deficiency (MPHD) has not been previously reported. We present a series of four children with cerebral palsy who were born before 29 weeks gestation who were referred to the regional endocrinology service, three for delayed puberty and one for short stature, in whom investigations identified MPHD...
October 27, 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27776846/-prevention-of-preterm-birth-complications-by-antenatal-corticosteroid-administration
#11
T Schmitz
OBJECTIVE: To evaluate short- and long-term benefits and risks associated with antenatal administration of a single course of corticosteroids and the related strategies: multiple and rescue courses. METHODS: The PubMed database, the Cochrane Library and the recommendations from the French and foreign obstetrical societies or colleges have been consulted. RESULTS: Antenatal administration of a single course of corticosteroids before 34 weeks of gestation is associated in the neonatal period with a significant reduction of respiratory distress syndrome (RDS), intraventricular hemorrhage (IVH), necrotizing enterocolitis (NEC) and death (LE1), and in possibly childhood with a reduction of cerebral palsy and increased psychomotor development index and intact survival (LE3)...
October 21, 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/27744459/dental-health-of-children-with-cerebral-palsy
#12
Basil M Jan, Mohammed M Jan
Cerebral palsy (CP) is a common chronic motor disorder with associated cognitive, communicative, and seizure disorders. Children with CP have a higher risk of dental problems creating significant morbidity that can further affect their wellbeing and negatively impact their quality of life. Screening for dental disease should be part of the initial assessment of any child with CP. The objective of this article is to present an updated overview of dental health issues in children with CP and outline important preventative and practical strategies to the management of this common comorbidity...
October 2016: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/27742529/association-of-gross-motor-function-classification-system-level-and-school-attendance-with-bone-mineral-density-in-patients-with-cerebral-palsy
#13
Ki Jin Jung, Soon-Sun Kwon, Chin Youb Chung, Kyoung Min Lee, Ki Hyuk Sung, Byung Chae Cho, Myoung Ki Chung, Seung Jun Moon, Jaeyoung Kim, Moon Seok Park
The present study aimed to evaluate bone mineral density (BMD) in children and adolescents with cerebral palsy (CP) and to critically analyze the effects of a variety of factors, particularly the Gross Motor Function Classification System (GMFCS) level, the Caregiver Priorities and Child Health Index of Life with Disabilities questionnaire, and the Pediatric Outcomes Data Collection Instrument (PODCI), on BMD. Fifty patients with CP who underwent dual-energy X-ray absorptiometry were included. Collected data included the extent of involvement, muscle tone, demographic data, factors determined through chart review, and laboratory results...
October 11, 2016: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/27718629/early-use-of-power-wheelchair-for-children-with-duchenne-muscular-dystrophy-a-narrative-review
#14
Michal Elboim-Gabyzon, Osnat Atun-Einy, Insaf Khoury-Assaf
PURPOSE: To review the literature on the existent evidence considering the use of power wheel chair (PWC) for children with DMD who can still walk independently. METHODS: A systematic literature search was conducted through nine databases by the three authors independently. Both quantitative and qualitative research designs were considered for inclusion. Studies were included only if the study population consisted of ambulatory children diagnosed with DMD. Data extraction was on participant characteristics, level of walking and on outcomes in term of impairment, function and participation domains (ICF, World Health Organization, 2001) in accordance to a structured diagram by the three authors independently...
October 9, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27687767/perspectives-in-neonatal-and-childhood-arterial-ischemic-stroke
#15
J Fluss, M Dinomais, M Kossorotoff, C Vuillerot, S Darteyre, S Chabrier
Over the last decade considerable advances have been made in the identification, understanding and management of pediatric arterial ischemic stroke. Such increasing knowledge has also brought new perspectives and interrogations in the current acute and rehabilitative care of these patients. Areas covered: In developed countries, focal cerebral arteriopathy is one of the most common causes of arterial ischemic stroke in childhood and imaging features are well characterized. However, there are ongoing debates regarding its underlying mechanisms, natural evolution and proper management...
October 12, 2016: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/27676704/recommendations-for-clinical-practice-after-neonatal-arterial-ischemic-stroke-clinical-monitoring-and-early-rehabilitation-intervention
#16
Carole Vuillerot, Mickael Dinomais, Stephane Marret, Stephane Chabrier, Thierry Debillon
Neonatal arterial ischemic stroke (NAIS) affects one child in 6-17 100,000-birth term neonates, most of these children will keep long-term motor and cognitive impairment. In 2014, initiated by the French Center for Pediatric Stroke in association with the French Society of Neonatology, a steering committee was created to propose clinical guidelines after NAIS. From all the relevant questions, the importance is given to long-term outcomes after a NAIS with a need for a better description of motor and cognitive outcomes after a NAIS in order to propose a more consensual monitoring for these children to improve their management...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27650433/igf-1-in-retinopathy-of-prematurity-a-cns-neurovascular-disease
#17
REVIEW
Raffael Liegl, Chatarina Löfqvist, Ann Hellström, Lois E H Smith
The retina is part of the central nervous system and both the retina as well as the brain can suffer from severe damage after very preterm birth. Retinopathy of prematurity is one of the major causes of blindness in these children and brain neuronal impairments including cognitive defects, cerebral palsy and intraventricular hemorrhage (IVH) are also complications of very preterm birth. Insulin-like growth factor 1 (IGF-1) acts to promote proliferation, maturation, growth and survival of neural cells. Low levels of circulating IGF-1 are associated with ROP and defects in the IGF-1 gene are associated with CNS disorders including learning deficits and brain growth restriction...
November 2016: Early Human Development
https://www.readbyqxmd.com/read/27633845/predictive-factors-for-inpatient-falls-among-children-with-cerebral-palsy
#18
Ebru Alemdaroğlu, Sibel Demir Özbudak, Sibel Mandiroğlu, Seda Alakoç Biçer, Neşe Özgirgin, Halil Uçan
: Inpatient falls are of significant concern. The aim of this prospective study was to determine the predictors of inpatient falls among children with cerebral palsy in a rehabilitation hospital. DESIGN AND METHODS: A total of 93 patients with cerebral palsy were assessed based on history, physical findings, the Selective Motor Control Test, the Gross Motor Functional Classification System, the Berg Balance Scale and the Manual Ability Classification System. Previous history of falls/frequent falls, and any falls which occurred during hospitalization, were recorded...
September 12, 2016: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/27613590/gastrocnemius-operating-length-with-ankle-foot-orthoses-in-cerebral-palsy
#19
Hwan Choi, Tishya Anne Leong Wren, Katherine Muterspaugh Steele
BACKGROUND: Many individuals with cerebral palsy wear ankle foot orthoses during daily life. Orthoses influence joint motion, but how they impact muscle remains unclear. In particular, the gastrocnemius is commonly stiff in cerebral palsy. Understanding whether orthoses stretch or shorten this muscle during daily life may inform orthosis design and rehabilitation. OBJECTIVES: This study investigated the impact of different ankle foot orthoses on gastrocnemius operating length during walking in children with cerebral palsy...
September 9, 2016: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/27606053/perinatal-neuroprotection-update
#20
REVIEW
Angie C Jelin, Kirsten Salmeen, Dawn Gano, Irina Burd, Mari-Paule Thiet
Antepartum, intrapartum, and neonatal events can result in a spectrum of long-term neurological sequelae, including cerebral palsy, cognitive delay, schizophrenia, and autism spectrum disorders [1]. Advances in obstetrical and neonatal care have led to survival at earlier gestational ages and consequently increasing numbers of periviable infants who are at significant risk for long-term neurological deficits. Therefore, efforts to decrease and prevent cerebral insults attempt not only to decrease preterm delivery but also to improve neurological outcomes in infants delivered preterm...
2016: F1000Research
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