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cerebral palsy prevention

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https://www.readbyqxmd.com/read/29756481/biofeedback-interventions-for-individuals-with-cerebral-palsy-a-systematic-review
#1
Alexander MacIntosh, Emily Lam, Vincent Vigneron, Nicolas Vignais, Elaine Biddiss
PURPOSE: The purpose of this study is to evaluate the quality of evidence of biofeedback interventions aimed at improving motor activities in people with Cerebral Palsy (CP). Second, to describe the relationship between intervention outcomes and biofeedback characteristics. METHODS: Eight databases were searched for rehabilitation interventions that provided external feedback and addressed motor activities. Two reviewers independently assessed and extracted data...
May 12, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29750055/noncommunicable-disease-and-multimorbidity-in-young-adults-with-cerebral-palsy
#2
Daniel G Whitney, Edward A Hurvitz, Jennifer M Ryan, Maureen J Devlin, Michelle S Caird, Zachary P French, Elie C Ellenberg, Mark D Peterson
Purpose: Individuals with cerebral palsy (CP) are at increased risk for frailty and chronic disease due to factors experienced throughout the lifespan, such as excessive sedentary behaviors and malnutrition. However, little is known about noncommunicable diseases (NCDs) and multimorbidity profiles in young adults with CP. The study objective was to compare NCD and multimorbidity profiles between young adults with and without CP. Methods: A clinic-based sample of adults (18-30 years) with (n=452) and without (n=448) CP was examined at the University of Michigan Medical Center...
2018: Clinical Epidemiology
https://www.readbyqxmd.com/read/29730660/perinatal-outcome-and-long-term-neurodevelopment-after-intracranial-haemorrhage-due-to-fetal-and-neonatal-alloimmune-thrombocytopenia
#3
Dian Winkelhorst, Marije M Kamphuis, Sylke J Steggerda, Monique Rijken, Dick Oepkes, Enrico Lopriore, Jeanine M M van Klink
OBJECTIVES: To evaluate the perinatal and long-term neurodevelopmental outcome in a cohort of children with intracranial haemorrhage (ICH) due to fetal and neonatal alloimmune thrombocytopenia (FNAIT) and to clearly outline the burden of this disease. SUBJECTS AND METHODS: We performed an observational cohort study and included all consecutive cases of ICH caused by FNAIT from 1993 to 2015 at Leiden University Medical Centre. Neurological, motor, and cognitive development were assessed at a minimum age of 1 year...
May 4, 2018: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/29714626/factors-associated-with-enhanced-gross-motor-progress-in-children-with-cerebral-palsy-a-register-based-study
#4
Gunfrid V Størvold, Reidun B Jahnsen, Kari Anne I Evensen, Ulla K Romild, Grete H Bratberg
AIM: To examine associations between interventions and child characteristics; and enhanced gross motor progress in children with cerebral palsy (CP). METHODS: Prospective cohort study based on 2048 assessments of 442 children (256 boys, 186 girls) aged 2-12 years registered in the Cerebral Palsy Follow-up Program and the Cerebral Palsy Register of Norway. Gross motor progress estimates were based on repeated measures of reference percentiles for the Gross Motor Function Measure (GMFM-66) in a linear mixed model...
May 1, 2018: Physical & Occupational Therapy in Pediatrics
https://www.readbyqxmd.com/read/29713307/fetal-neuroprotection-by-magnesium-sulfate-from-translational-research-to-clinical-application
#5
REVIEW
Clément Chollat, Loïc Sentilhes, Stéphane Marret
Despite improvements in perinatal care, preterm birth still occurs regularly and the associated brain injury and adverse neurological outcomes remain a persistent challenge. Antenatal magnesium sulfate administration is an intervention with demonstrated neuroprotective effects for preterm births before 32 weeks of gestation (WG). Owing to its biological properties, including its action as an N -methyl-d-aspartate receptor blocker and its anti-inflammatory effects, magnesium is a good candidate for neuroprotection...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29710024/-transient-recurrent-white-matter-lesions-in-x-linked-charcot-marie-tooth-disease-with-heterozygote-mutation-of-gjb1-gene-case-report-of-a-female-patient
#6
Makoto Takemaru, Yutaka Shimoe, Kota Sato, Akihiro Hashiguchi, Hiroshi Takashima, Masaru Kuriyama
A 32-year-old woman showed transient central type facial nerve palsy and bulbar symptoms. Brain MRI revealed high intensity signals in the cerebral white matter, splenium of corpus callosum, and posterior limb of internal capsule. Two elder brothers of the patient had distal dominant peripheral neuropathies in four limbs. In this family, the point mutation of GJB1 gene, encoding connexin 32, was revealed and X-linked Charcot-Marie-Tooth disease (CMTX1) was diagnosed. The presented case was a heterozygote of this mutation...
April 28, 2018: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/29696043/prevalence-of-vitamin-d-deficiency-and-associated-risk-factors-in-cerebral-palsy-a-study-in-north-west-of-iran
#7
Vahideh Toopchizadeh, Mohammad Barzegar, Shahab Masoumi, Fatemeh Jahanjoo
Objective: This study aimed to compare the prevalence of 25-hydroxyvitamin D deficiency in cerebral palsied (CP) with healthy control children and evaluate possible correlations between 25-hydroxyvitamin D and severity of CP and motor function. Materials & Methods: In this case-control study, serum levels of 25-hydroxyvitamin D were evaluated in 65 children with CP and compared with 65 healthy children referred to Tabriz Pediatric Hospital, Tabriz, northwestern Iran in 2015...
2018: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/29679933/slip-avoidance-strategies-in-children-with-bilateral-spastic-cerebral-palsy-and-crouch-gait
#8
Ana Francisca Rozin Kleiner, Ilaria Pacifici, Claudia Condoluci, Chiarella Sforza, Manuela Galli
BACKGROUND: A slip occurs when the required friction (RCOF) to prevent slipping at the foot/floor interfaces exceeds the available friction. The RCOF is dependent upon the biomechanics features of individuals and their gait. On the other hand, the available friction depends on environmental features. Once individuals with crouch gait have their biomechanics of gait completely altered, how do they interact with a supporting surface? The aim was to quantify the RCOF in children with bilateral spastic cerebral palsy (BSCP) and crouch gait...
April 11, 2018: Clinical Biomechanics
https://www.readbyqxmd.com/read/29616203/non-invasive-brain-stimulation-in-children-with-unilateral-cerebral-palsy-a-protocol-and-risk-mitigation-guide
#9
Bernadette T Gillick, Andrew M Gordon, Tim Feyma, Linda E Krach, Jason Carmel, Tonya L Rich, Yannick Bleyenheuft, Kathleen Friel
Non-invasive brain stimulation has been increasingly investigated, mainly in adults, with the aims of influencing motor recovery after stroke. However, a consensus on safety and optimal study design has not been established in pediatrics. The low incidence of reported major adverse events in adults with and without clinical conditions has expedited the exploration of NIBS in children with paralleled purposes to influence motor skill development after neurological injury. Considering developmental variability in children, with or without a neurologic diagnosis, adult dosing and protocols may not be appropriate...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29610937/paediatric-musculoskeletal-disease-in-kumi-district-uganda-a-cross-sectional-survey
#10
Kristin Alves, Norgrove Penny, Olive Kobusingye, Robert Olupot, Jeffrey N Katz, Coleen S Sabatini
PURPOSE: The purpose of this study is to estimate the burden of musculoskeletal disease among children treated in Kumi District, Uganda, to inform training, capacity-building efforts, and resource allocation. METHODS: We conducted a retrospective cohort study by reviewing the musculoskeletal (MSK) clinic and community outreach logs for children (age < 18 years) seen at Kumi Hospital in Kumi, Uganda, between January 2013 and December 2015. For each patient, we recorded the age, sex, diagnosis, and treatment recommendation...
April 2, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29597096/a-sustainable-solution-for-the-activities-of-the-european-network-for-surveillance-of-congenital-anomalies-eurocat-as-part-of-the-eu-platform-on-rare-diseases-registration
#11
REVIEW
Agnieszka Kinsner-Ovaskainen, Monica Lanzoni, Ester Garne, Maria Loane, Joan Morris, Amanda Neville, Ciarán Nicholl, Judith Rankin, Anke Rissmann, David Tucker, Simona Martin
The European Commission through its Directorates-General Joint Research Centre (DG JRC) and Health and Food Safety (DG SANTE) is developing the European Platform on Rare Diseases Registration (EU RD Platform) with the objective to set European-level standards for data collection and data sharing. In the field of rare diseases the EU RD Platform will be a source of information on available rare disease patient data with large transnational European coverage. One main function of the EU RD Platform is to enable interoperability for the >600 existing RD registries in Europe...
March 27, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29594463/traumatic-brain-injury-in-indian-children
#12
REVIEW
Krishna Chaitanya, Archana Addanki, Rajendra Karambelkar, Rakesh Ranjan
INTRODUCTION: Traumatic brain injury (TBI) in children and adolescents is a community-based medical and educational challenge world-over due to increasing urbanization and motorization. In India, children between 1 to 15 years constitute significant proportion of the total population, who are vulnerable for TBI. In developed countries, pediatric trauma mortality still represents more than half of all childhood fatalities, which is 18 times more common than brain tumors. In this study, we attempted to analyze epidemiological factors, management, and outcome of TBI in children at a tertiary care center in Pune, Maharashtra...
March 29, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29578990/effects-of-postural-management-on-hip-migration-in-children-with-cerebral-palsy-a-systematic-review
#13
Christiaan Gmelig Meyling, Marjolijn Ketelaar, Marie-Anne Kuijper, Jeanine Voorman, Annemieke I Buizer
PURPOSE: To review the existing literature on the effects of postural management on hip migration in children with cerebral palsy. METHODS: A systematic literature search was performed using 5 databases. Quality of articles was assessed and study designs were appraised according to the American Academy of Cerebral Palsy and Developmental Medicine Systematic Review Method. RESULTS: Eight of 655 identified studies were included, reporting postural management in children with cerebral palsy...
April 2018: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/29572812/the-risk-burden-and-management-of-non-communicable-diseases-in-cerebral-palsy-a-scoping-review
#14
REVIEW
Jennifer M Ryan, Elizabeth Allen, John Gormley, Edward A Hurvitz, Mark D Peterson
AIM: To examine the risk, burden, and management of non-communicable diseases (NCDs) among people with cerebral palsy (CP). METHOD: Databases (Ovid MEDLINE, Embase Ovid, CINAHL Plus) were systematically searched up to August 2017. Data on the prevalence of risk factors for, and the burden and management of, cardiovascular diseases, diabetes, cancers, and respiratory diseases were extracted. RESULTS: Thirty-six studies that examined the prevalence of risk factors among people with CP were identified...
March 24, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29559892/-in-utero-administration-of-drugs-targeting-microglia-improves-the-neurodevelopmental-outcome-following-cytomegalovirus-infection-of-the-rat-fetal-brain
#15
Robin Cloarec, Sylvian Bauer, Natacha Teissier, Fabienne Schaller, Hervé Luche, Sandra Courtens, Manal Salmi, Vanessa Pauly, Emilie Bois, Emilie Pallesi-Pocachard, Emmanuelle Buhler, François J Michel, Pierre Gressens, Marie Malissen, Thomas Stamminger, Daniel N Streblow, Nadine Bruneau, Pierre Szepetowski
Congenital cytomegalovirus (CMV) infections represent one leading cause of neurodevelopmental disorders. Recently, we reported on a rat model of CMV infection of the developing brain in utero , characterized by early and prominent infection and alteration of microglia-the brain-resident mononuclear phagocytes. Besides their canonical function against pathogens, microglia are also pivotal to brain development. Here we show that CMV infection of the rat fetal brain recapitulated key postnatal phenotypes of human congenital CMV including increased mortality, sensorimotor impairment reminiscent of cerebral palsy, hearing defects, and epileptic seizures...
2018: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29555725/predicting-respiratory-hospital-admissions-in-young-people-with-cerebral-palsy
#16
Amanda Marie Blackmore, Natasha Bear, Eve Blair, Katherine Langdon, Lisa Moshovis, Kellie Steer, Andrew C Wilson
OBJECTIVE: To determine the early predictors of respiratory hospital admissions in young people with cerebral palsy (CP). DESIGN: A 3-year prospective cohort study using linked data. PATIENTS: Children and young people with CP, aged 1 to 26 years. MAIN OUTCOME MEASURES: Self-reported and carer-reported respiratory symptoms were linked to respiratory hospital admissions (as defined by the International Statistical Classification of Diseases and Related Health Problems 10th Revision codes) during the following 3 years...
March 19, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29536527/mid-term-development-of-hamstring-tendon-length-and-velocity-after-distal-femoral-extension-osteotomy-in-children-with-bilateral-cerebral-palsy-a-retrospective-cohort-study
#17
Firooz Salami, Julia Wagner, Stefan van Drongelen, Matthias C M Klotz, Thomas Dreher, Sebastian I Wolf, Mirjam Niklasch
AIM: Flexed knee gait can be treated with distal femoral extension osteotomy (DFEO) and additional patellar tendon advancement (PTA) in children with cerebral palsy (CP). This study assesses changes in hamstring muscle tendon length (MTL) and velocity after DFEO (+PTA). METHOD: Nineteen children (mean age 13y [standard deviation 3y] at surgery) with CP and flexed knee gait who were treated with DFEO (15 limbs) or DFEO+PTA (10 limbs) were retrospectively included in this study...
March 14, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29510423/genetic-variation-magnesium-sulfate-exposure-and-adverse-neurodevelopmental-outcomes-following-preterm-birth
#18
Erin A S Clark, Steven J Weiner, Dwight J Rouse, Brian M Mercer, Uma M Reddy, Jay D Iams, Ronald J Wapner, Yoram Sorokin, Fergal D Malone, Mary J O'Sullivan, Alan M Peaceman, Gary D V Hankins, Donald J Dudley, Steve N Caritis
OBJECTIVE:  To evaluate the association of magnesium sulfate (MgSO4 ) exposure and candidate gene polymorphisms with adverse neurodevelopmental outcomes following preterm birth. STUDY DESIGN:  We performed a nested case-control analysis of a randomized trial of maternal MgSO4 before anticipated preterm birth for the prevention of cerebral palsy (CP). Cases were children who died within 1 year of life or were survivors with abnormal neurodevelopment at age 2 years...
March 6, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29478499/magnesium-sulfate-prevents-cerebral-palsy-in-premature-infants
#19
Megan E Paulsen, Robert M Dietz
No abstract text is available yet for this article.
March 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29475879/corticosteroids-for-the-prevention-of-bronchopulmonary-dysplasia-in-preterm-infants-a-network-meta-analysis
#20
Linan Zeng, Jinhui Tian, Fujian Song, Wenrui Li, Lucan Jiang, Ge Gui, Yang Zhang, Long Ge, Jing Shi, Xin Sun, Dezhi Mu, Lingli Zhang
OBJECTIVE: To determine the comparative efficacy and safety of corticosteroids in the prevention of bronchopulmonary dysplasia (BPD) in preterm infants. STUDY DESIGN: We systematically searched PubMed, EMBASE and the Cochrane Library. Two reviewers independently selected randomised controlled trials (RCTs) of postnatal corticosteroids in preterm infants. A Bayesian network meta-analysis and subgroup analyses were performed. RESULTS: We included 47 RCTs with 6747 participants...
February 23, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
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