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Autism prevention

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https://www.readbyqxmd.com/read/29678400/predictors-of-social-relationships-for-children-with-special-health-care-needs
#1
Cara Sisk, George Chitiyo, Ashley Akenson
Children with special health care needs (CSHCN) experience various developmental challenges including difficulties in social relationships with peers. Using data from the Centers for Disease Control and Prevention's National Survey of Children with Special Health Care Needs 2009-2010, this correlational study examined predictors of difficulty making and keeping friends among CSHCN. Binary logistic regression was used to analyze the data. Findings indicate statistical significance for 12 out of 14 predictor variables...
April 17, 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29673576/the-role-of-genetic-variation-of-human-metabolism-for-bmi-mental-traits-and-mental-disorders
#2
Johannes Hebebrand, Triinu Peters, Dick Schijven, Moritz Hebebrand, Corinna Grasemann, Thomas W Winkler, Iris M Heid, Jochen Antel, Manuel Föcker, Lisa Tegeler, Lena Brauner, Roger A H Adan, Jurjen J Luykx, Christoph U Correll, Inke R König, Anke Hinney, Lars Libuda
OBJECTIVE: The aim was to assess whether loci associated with metabolic traits also have a significant role in BMI and mental traits/disorders METHODS: We first assessed the number of single nucleotide polymorphisms (SNPs) with genome-wide significance for human metabolism (NHGRI-EBI Catalog). These 516 SNPs (216 independent loci) were looked-up in genome-wide association studies for association with body mass index (BMI) and the mental traits/disorders educational attainment, neuroticism, schizophrenia, well-being, anxiety, depressive symptoms, major depressive disorder, autism-spectrum disorder, attention-deficit/hyperactivity disorder, Alzheimer's disease, bipolar disorder, aggressive behavior, and internalizing problems...
April 3, 2018: Molecular Metabolism
https://www.readbyqxmd.com/read/29607853/evaluation-of-oral-health-status-and-influential-factors-in-children-with-autism
#3
S Onol, Z Kırzıoğlu
Aims: The aim of the present study was to comparatively analyze oral health status and influential factors in children with autism living in the Western Mediterranean Region of Turkey. Subjects and Methods: This cross-sectional study was conducted in two steps: 1 - questionnaire and 2 - interview. This study was conducted at the Department of Pediatric Dentistry, Faculty of Dentistry, Süleyman Demirel University, Isparta, Turkey, within the period from March to July 2016...
April 2018: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29607562/risk-factors-and-topographies-for-self-injurious-behaviour-in-a-sample-of-adults-with-intellectual-developmental-disorders
#4
A Folch, M J Cortés, L Salvador-Carulla, P Vicens, M Irazábal, S Muñoz, L Rovira, C Orejuela, J M Haro, E Vilella, R Martínez-Leal
BACKGROUND: Self-injurious behaviour (SIB) is a prevalent form of challenging behaviour in people with intellectual developmental disorders (IDD). Existing research has yielded conflicting findings concerning the major risk factors involved, and in addition, SIB shows multiple topographies and presentations. Although presence of autism spectrum disorders (ASD) and severity of intellectual disability (ID) are known risk factors for SIB, there are no studies comparing SIB topographies by severity degrees of ID and ASD...
April 1, 2018: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/29589272/embedding-autism-spectrum-disorder-diagnosis-within-the-medical-home-decreasing-wait-times-through-streamlined-assessment
#5
Jeffrey F Hine, Catherine G Herrington, Alice M Rothman, Rachel L Mace, Barron L Patterson, Kathryn L Carlson, Zachary E Warren
Long waits for diagnostic assessment prevent early identification of children suspected of having autism spectrum disorder. We evaluated the benefit of embedded diagnostic consultation within primary care clinics. Using a streamlined diagnostic model, 119 children with concerns for autism spectrum disorder were seen over 14 months. Diagnostic clarity was determined through streamlined assessment for 59% of the children, while others required follow-up. Latency from first concern to diagnosis was 55 days and median age at diagnosis was 32 months: considerably lower than national averages or comparable tertiary clinics...
March 27, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29588970/prevalence-risk-factors-and-neurobehavioral-comorbidities-of-epilepsy-in-kenyan-children
#6
Charles J Kind, Charles R J C Newton, Symon M Kariuki
Objective: To investigate the prevalence, risk factors, clinical features, and neurobehavioral comorbidities of epilepsy and acute symptomatic seizures in school-aged children in Kilifi, Kenya. Methods: Randomly selected children (N = 11,223) were screened for epilepsy and other neurodevelopmental disorders. Those who screened positive were invited for further clinical, electroencephalographic (EEG), and neuropsychological evaluations. Prevalence was measured by dividing cases by screened population, providing Agresti-Coull confidence intervals (CIs)...
December 2017: Epilepsia Open
https://www.readbyqxmd.com/read/29582071/vaccination-patterns-in-children-after-autism-spectrum-disorder-diagnosis-and-in-their-younger-siblings
#7
Ousseny Zerbo, Sharareh Modaressi, Kristin Goddard, Edwin Lewis, Bruce H Fireman, Matthew F Daley, Stephanie A Irving, Lisa A Jackson, James G Donahue, Lei Qian, Darios Getahun, Frank DeStefano, Michael M McNeil, Nicola P Klein
Importance: In recent years, rates of vaccination have been declining. Whether this phenomenon disproportionately affects children with autism spectrum disorder (ASD) or their younger siblings is unknown. Objectives: To investigate if children after receiving an ASD diagnosis obtain their remaining scheduled vaccines according to the Advisory Committee on Immunization Practices (ACIP) recommendations and to compare the vaccination patterns of younger siblings of children with ASD with the vaccination patterns of younger siblings of children without ASD...
March 26, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/29574739/reimagining-the-environment-in-developmental-psychopathology-from-molecules-to-effective-interventions
#8
EDITORIAL
Pasco Fearon
The Journal of Child Psychology and Psychiatry's Annual Research Review (ARR) is a must-read special issue of the journal that presents a series of major reviews of key topics in the field. This year the ARR consists of eight reviews, each accompanied by a commentary from a leading expert in the field, on a diverse range of topics addressing, in complementary ways, the key role of the environment in child psychopathology and in leveraging change in the service of prevention and intervention. Topics include epigenetics, stress physiology, neonatal imaging, interparental conflict, bullying, autism treatments and suicide...
April 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29570569/sensitivity-and-specificity-of-2-autism-screeners-among-referred-children-between-16-and-48-months-of-age
#9
Louisa A Salisbury, Jonathan D Nyce, Charles D Hannum, R Christopher Sheldrick, Ellen C Perrin
OBJECTIVE: Autism screening is recommended by the American Academy of Pediatrics and the Centers for Disease Control and Prevention at ages 18 and 24 months. Popular screening tests have been validated for the age range of 16 to 30 months. However, only a minority of children with autism spectrum disorder (ASD) are identified by age 3 years, and many are not identified until after they enter school. Thus, we aimed to measure the sensitivity and specificity of 2 available screening tests for ASDs in children older than 30 months...
April 2018: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29566458/chronic-stress-and-impulsive-risk-taking-predict-increases-in-visceral-fat-over-18-months
#10
Ashley E Mason, Samantha Schleicher, Michael Coccia, Elissa S Epel, Kirstin Aschbacher
OBJECTIVE: The aim of this study was to examine whether baseline chronic stress and impulsive risk-taking synergistically predict changes in visceral fat among healthy mothers in an observational, longitudinal, 18-month study. METHODS: A prospective cohort of 113 adult women (age, mean ± SD: 42.83 ± 4.70; BMI, mean ± SD: 24.86 ± 4.32; 74%, n = 84 white) completed assessments at baseline and 18-month follow-up. Chronically stressed mothers caring for a child with an autism spectrum disorder ("caregivers"; n = 72 participants) were compared with lower stress mothers caring for a neurotypical child ("controls"; n = 41)...
March 22, 2018: Obesity
https://www.readbyqxmd.com/read/29563885/interplay-between-peripheral-and-central-inflammation-in-autism-spectrum-disorders-possible-nutritional-and-therapeutic-strategies
#11
REVIEW
Claudia Cristiano, Adriano Lama, Francesca Lembo, Maria P Mollica, Antonio Calignano, Giuseppina Mattace Raso
Pre- and post-natal factors can affect brain development and function, impacting health outcomes with particular relevance to neurodevelopmental diseases, such as autism spectrum disorders (ASDs). Maternal obesity and its associated complications have been related to the increased risk of ASDs in offspring. Indeed, animals exposed to maternal obesity or high fat diets are prone to social communication impairment and repetitive behavior, the hallmarks of autism. During development, fatty acids and sugars, as well as satiety hormones, like insulin and leptin, and inflammatory factors related to obesity-induced low grade inflammation, could play a role in the impairment of neuroendocrine system and brain neuronal circuits regulating behavior in offspring...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29558816/prenatal-primary-prevention-of-mental-illness-by-micronutrient-supplements-in-pregnancy
#12
Robert Freedman, Sharon K Hunter, M Camille Hoffman
Genes, infection, malnutrition, and other factors affecting fetal brain development are a major component of risk for a child's emotional development and later mental illnesses, including schizophrenia, bipolar disorder, and autism. Prenatal interventions to ameliorate that risk have yet to be established for clinical use. A systematic review of prenatal nutrients and childhood emotional development and later mental illness was performed. Randomized trials of folic acid, phosphatidylcholine, and omega-3 fatty acid supplements assess effects of doses beyond those adequate to remedy deficiencies to promote normal fetal development despite genetic and environmental risks...
March 21, 2018: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29554290/intentions-to-use-a-novel-zika-vaccine-the-effects-of-misbeliefs-about-the-mmr-vaccine-and-perceptions-about-zika
#13
Yotam Ophir, Kathleen Hall Jamieson
Background: People's intentions to use vaccines are influenced by their beliefs about both the specific vaccine and the disease it prevents. In the absence of firm beliefs about Zika virus (ZIKV), individuals may base their intentions to vaccinate against it on beliefs about other vaccines, and specifically the misbelief that MMR causes autism. Methods: A survey of 3337 Americans, using a random-digit-dialing sample of landline telephone households and cell-phones...
March 15, 2018: Journal of Public Health
https://www.readbyqxmd.com/read/29551982/prevalence-and-risk-factors-of-anxiety-in-a-clinical-dutch-sample-of-children-with-an-autism-spectrum-disorder
#14
Lieke A M W Wijnhoven, Daan H M Creemers, Ad A Vermulst, Isabela Granic
Anxiety is highly prevalent in children with an autism spectrum disorder (ASD). However, there is inconsistency in studies investigating the prevalence and risk factors of anxiety in children with ASD. Therefore, the first aim of this study was to give an overview of the prevalence of anxiety symptoms in a clinical Dutch sample of children with ASD. The second aim was to investigate age, gender, ASD subtype, and IQ as potential risk factors for anxiety in this sample. In total, 172 children with ASD (age, 8-15 years) and their parents participated in this study...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29550367/contemporary-strategies-for-dissecting-the-neuronal-basis-of-neurodevelopmental-disorders
#15
Dong-Oh Seo, Laura E Motard, Michael R Bruchas
Great efforts in clinical and basic research have shown progress in understanding the neurobiological mechanisms of neurodevelopmental disorders, such as autism, schizophrenia, and attention-deficit hyperactive disorders. Literature on this field have suggested that these disorders are affected by the complex interaction of genetic, biological, psychosocial and environmental risk factors. However, this complexity of interplaying risk factors during neurodevelopment has prevented a complete understanding of the causes of those neuropsychiatric symptoms...
March 14, 2018: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29546561/early-origins-of-autism-comorbidity-neuropsychiatric-traits-correlated-in-childhood-are-independent-in-infancy
#16
Zoë W Hawks, Natasha Marrus, Anne L Glowinski, John N Constantino
Previous research has suggested that behavioral comorbidity is the rule rather than the exception in autism. The present study aimed to trace the respective origins of autistic and general psychopathologic traits-and their association-to infancy. Measurements of autistic traits and early liability for general psychopathology were assessed in 314 twins at 18 months, ascertained from the general population using birth records. 222 twins were re-evaluated at 36 months. Standardized ratings of variation in social communication at 18 months were highly heritable and strongly predicted autistic trait scores at 36 months...
March 16, 2018: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/29529521/prenatal-dexamethasone-treatment-in-the-context-of-at-risk-cah-pregnancies-long-term-behavioral-and-cognitive-outcome
#17
Leif Karlsson, Anna Nordenström, Tatja Hirvikoski, Svetlana Lajic
Dexamethasone (DEX) is used to prevent prenatal virilization in female fetuses with congenital adrenal hyperplasia (CAH). Since treatment has to be started before the genotype of the fetus is known, 7 out of 8 fetuses will be exposed to DEX without benefit. Previously, we have observed negative effects on cognition and behavior in DEX treated children. Here we evaluated neuropsychological functions, psychopathology and autistic traits in non-CAH DEX-treated adults exposed during the first trimester of fetal life (duration 6...
March 1, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29521536/autism-narratives-in-media-coverage-of-the-mmr-vaccine-autism-controversy-under-a-crip-futurism-framework
#18
Benjamin W Mann
While previous studies in health communication have examined online news media regarding autism, there is a lack of research that critically examines how such media representations may stigmatize autism and seeks to eliminate the condition, particularly in the context of the resurging measles, mumps, and rubella (MMR) vaccine-autism controversy. To address this gap in the literature, this study analyzes 153 articles that engage the MMR vaccine-autism controversy from the top 10 online news sources in the U...
March 9, 2018: Health Communication
https://www.readbyqxmd.com/read/29518826/-the-identification-and-treatment-of-common-comorbidity-in-children-with-autism-spectrum-disorder
#19
(no author information available yet)
No abstract text is available yet for this article.
March 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29515991/vaccination-perceptions-of-college-students-with-and-without-vaccination-waiver
#20
Emmanuel D Jadhav, Danielle L Winkler, Billie S Anderson
Introduction: The resurgence of vaccine preventable diseases occurs more often among intentionally unvaccinated individuals, placing at direct risk young adults not caught up on vaccinations. The objectives of this study were to characterize the sociodemographic characteristics of young adults with and without vaccination waivers and identify their perceived benefits, barriers, and influencers of vaccination. Methods: Young adults ( n  = 964) from a Midwestern rural university responded to a survey (fall 2015-spring 2016) designed to identify their perception toward vaccination...
2018: Frontiers in Public Health
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