keyword
MENU ▼
Read by QxMD icon Read
search

Autism prevention

keyword
https://www.readbyqxmd.com/read/28514706/evaluation-of-behavioral-change-after-adenotonsillectomy-for-obstructive-sleep-apnea-in-children-with-autism-spectrum-disorder
#1
Emi Murata, Ikuko Mohri, Kumi Kato-Nishimura, Jiro Iimura, Makoto Ogawa, Masaya Tachibana, Yuko Ohno, Masako Taniike
BACKGROUND AND OBJECTIVE: Obstructive sleep apnea (OSA) may affect daily cognitive functioning in children. The aims of our study were two-fold. The first aim was to detect, using the Child Behavior Checklist (CBCL), whether adenotonsillectomy (AT) for the treatment of OSA improved the behavior of children with autism spectrum disorder (ASD). The second aim was to identify characteristics for behavioral improvement following the treatment of OSA in these children with ASD. METHODS: The behaviors of ASD children aged 5-14 years diagnosed as having OSA (n=30) were evaluated using CBCL before and after AT...
May 14, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28495514/neurobehavioral-risks-of-ssris-in-pregnancy-comparing-human-and-animal-data
#2
REVIEW
Asher Ornoy
During the last twenty years, in spite of extensive literature regarding the use of SSRIs in pregnancy, confusion still exists as to possible long-term risks of these drugs on the offspring. Possible negative effects relate to neurodevelopmental outcome and association with Autism Spectrum Disorder (ASD). Most neurodevelopmental follow up studies did not find significant cognitive impairment except from some apparently transient, gross motor delay and slight impairment of language abilities. The literature on the possible association of SSRIs with ASD is inconsistent, and if an association exists it is apparently throughout pregnancy...
May 8, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28494598/dental-trauma-in-italian-children-and-adolescents-with-special-health-care-needs-a-cross-sectional-retrospective-study
#3
S Bagattoni, A Sadotti, G D'Alessandro, G Piana
AIM: Dental trauma is a frequent finding in people with special health care needs. The aim of this study was to determine the prevalence of dental trauma in a sample of Italian children and adolescents with special health care needs. MATERIALS AND METHODS: 556 medical and dental records of children and adolescents visited from January 2010 to March 2015 were examined. Information about medical diagnosis, gender, site and type of dental trauma (DT) were collected...
March 2017: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28490020/maternal-inflammation-results-in-altered-tryptophan-metabolism-in-rabbit-placenta-and-fetal-brain
#4
Monica Williams, Zhi Zhang, Elizabeth Nance, Julia L Drewes, Wojciech G Lesniak, Sarabdeep Singh, Diane C Chugani, Kannan Rangaramanujam, David R Graham, Sujatha Kannan
Maternal inflammation has been linked to neurodevelopmental and neuropsychiatric disorders such as cerebral palsy, schizophrenia, and autism. We had previously shown that intrauterine inflammation resulted in a decrease in serotonin, one of the tryptophan metabolites, and a decrease in serotonin fibers in the sensory cortex of newborns in a rabbit model of cerebral palsy. In this study, we hypothesized that maternal inflammation results in alterations in tryptophan pathway enzymes and metabolites in the placenta and fetal brain...
May 11, 2017: Developmental Neuroscience
https://www.readbyqxmd.com/read/28483756/drowning-fatalities-in-childhood-the-role-of-pre-existing-medical-conditions
#5
Richard C Franklin, John H Pearn, Amy E Peden
OBJECTIVES: This study is an analysis of the contribution of pre-existing medical conditions to unintentional fatal child (0-14 years) drowning and a of critique prevention stratagems, with an exploration of issues of equity in recreation. DESIGN: This study is a total population, cross-sectional audit of all demographic, forensic and on-site situational details surrounding unintentional fatal drowning of children 0-14 years in Australia for the period of 1 July 2002 to 30 June 2012...
May 8, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28479531/-structural-brain-development-in-healthy-children-and-adolescents
#6
Izumi Matsudaira, Ryuta Kawashima, Yasuyuki Taki
Brain maturation progresses throughout childhood into adolescence. Investigating the mechanism of brain development during these periods in healthy people is necessary for some clinical purposes. For example, these mechanisms are needed to investigate the mechanism of impaired brain maturation in neurodevelopmental disorders-such as autism spectrum disorders or attention-deficit hyper disorder-and improve early prevention of psychiatric or neurodegenerative diseases like depression or Alzheimer's disease. Voxel-based morphometry (VBM) is an effective way to analyze brain magnetic resonance images (MRI) of children and adolescents, as the brain structures of children and adolescents vary widely depending on their age, sex, and several other factors...
May 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/28463237/epigenetic-and-transgenerational-mechanisms-in-infection-mediated-neurodevelopmental-disorders
#7
REVIEW
U Weber-Stadlbauer
Prenatal infection is an environmental risk factor for various brain disorders with neurodevelopmental components, including autism spectrum disorder and schizophrenia. Modeling this association in animals shows that maternal immune activation negatively affects fetal brain development and leads to the emergence of behavioral disturbances later in life. Recent discoveries in these preclinical models suggest that epigenetic modifications may be a critical molecular mechanism by which prenatal immune activation can mediate changes in brain development and functions, even across generations...
May 2, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28455196/maternal-il-17a-in-autism
#8
REVIEW
Helen Wong, Charles Hoeffer
Although autism spectrum disorder (ASD) has a strong genetic basis, its etiology is complex, with several genetic factors likely to be involved as well as environmental factors. Immune dysregulation has gained significant attention as a causal mechanism in ASD pathogenesis. ASD has been associated with immune abnormalities in the brain and periphery, including inflammatory disorders and autoimmunity in not only the affected individuals but also their mothers. Prenatal exposure to maternal immune activation (MIA) has been implicated as an environmental risk factor for ASD...
April 25, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/28453662/mglur5-tunes-ngf-trka-signaling-to-orient-spiny-stellate-neuron-dendrites-toward-thalamocortical-axons-during-whisker-barrel-map-formation
#9
Jui-Yen Huang, Hui-Chen Lu
Neurons receive and integrate synaptic inputs at their dendrites, thus dendritic patterning shapes neural connectivity and behavior. Aberrant dendritogenesis is present in neurodevelopmental disorders such as Down's syndrome and autism. Abnormal glutamatergic signaling has been observed in these diseases, as has dysfunction of the metabotropic glutamate receptor 5 (mGluR5). Deleting mGluR5 in cortical glutamatergic neurons disrupted their coordinated dendritic outgrowth toward thalamocortical axons and perturbed somatosensory circuits...
April 27, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28446959/gestational-vitamin-d-deficiency-and-autism-spectrum-disorder
#10
Anna A E Vinkhuyzen, Darryl W Eyles, Thomas H J Burne, Laura M E Blanken, Claudia J Kruithof, Frank Verhulst, Tonya White, Vincent W Jaddoe, Henning Tiemeier, John J McGrath
BACKGROUND: There is growing interest in linking vitamin D deficiency with autism spectrum disorders (ASDs). The association between vitamin D deficiency during gestation, a critical period in neurodevelopment, and ASD is not well understood. AIMS: To determine the association between gestational vitamin D status and ASD. METHOD: Based on a birth cohort (n=4334), we examined the association between 25-hydroxyvitamin D (25OHD), assessed from both maternal mid-gestation sera and neonatal sera, and ASD (defined by clinical records; n=68 cases)...
March 2017: BJPsych Open
https://www.readbyqxmd.com/read/28441171/prevalence-of-psychopathology-in-children-of-parents-with-mental-illness-and-or-addiction-an-up-to-date-narrative-review
#11
Sophie Leijdesdorff, Karin van Doesum, Arne Popma, Rianne Klaassen, Therese van Amelsvoort
PURPOSE OF REVIEW: Children of parents with a mental illness and/or addiction are at high risk for developing a mental illness themselves. Parental mental illness is highly prevalent leading to a serious number of children at high risk. The aim of this review is to give an up-to-date overview of psychopathology in children of parents with various mental illnesses and/or addiction, based on recent literature. RECENT FINDINGS: Worldwide, 15-23% of children live with a parent with a mental illness...
April 22, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28438881/prevalence-of-congenital-cytomegalovirus-infection-assessed-through-viral-genome-detection-in-dried-blood-spots-in-children-with-autism-spectrum-disorders
#12
Ivan Gentile, Emanuela Zappulo, Maria Pia Riccio, Sandro Binda, Laura Bubba, Laura Pellegrinelli, Domenico Scognamiglio, Francesca Operto, Lucia Margari, Guglielmo Borgia, Carmela Bravaccio
BACKGROUND/AIM: Autism spectrum disorders (ASD) are neurodevelopmental disorders without a definitive etiology in most cases. Environmental factors, such as viral infections, have been linked with anomalies in brain growth, neuronal development, and functional connectivity. Congenital cytomegalovirus (CMV) infection has been associated with the onset of ASD in several case reports. The aim of this study was to evaluate the prevalence of congenital CMV infection in children with ASD and in healthy controls...
May 2017: In Vivo
https://www.readbyqxmd.com/read/28396640/vitamin-d-deficiency-as-a-potential-environmental-risk-factor-in-multiple-sclerosis-schizophrenia-and-autism
#13
REVIEW
Eva Kočovská, Fiona Gaughran, Amir Krivoy, Ute-Christiane Meier
In this short review, we want to summarize the current findings on the role of vitamin-D in multiple sclerosis (MS), schizophrenia, and autism. Many studies have highlighted hypovitaminosis-D as a potential environmental risk factor for a variety of conditions such as MS, asthma, cardiovascular disease, and, more recently, psychiatric diseases. However, whether hypovitaminosis-D is a potential causative factor for the development or activity in these conditions or whether hypovitaminosis-D may be due to increased vitamin-D consumption by an activated immune system (reverse causation) is the focus of intense research...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28389841/an-initial-case-series-of-intensive-cognitive-behavioral-therapy-for-obsessive-compulsive-disorder-in-adolescents-with-autism-spectrum-disorder
#14
Marina Iniesta-Sepúlveda, Joshua M Nadeau, Amaya Ramos, Brian Kay, Bradley C Riemann, Eric A Storch
Obsessive-compulsive disorder (OCD) is prevalent among youth with autism spectrum disorder (ASD). Cognitive-behavioral therapy (CBT) with ASD-specific modifications has support for treating OCD in this population; however, use of intensive CBT in youth with ASD and severe OCD has not been tested. The current study examined the preliminary effectiveness of an individualized intensive CBT protocol for OCD in adolescents with ASD. Nine adolescents (aged 11-17 years) completed a regimen of intensive CBT (range 24-80 daily sessions) incorporating exposure with response prevention (ERP)...
April 7, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/28376888/daily-administration-of-yokukansan-and-keishito-prevents-social-isolation-induced-behavioral-abnormalities-and-down-regulation-of-phosphorylation-of-neuroplasticity-related-signaling-molecules-in-mice
#15
COMPARATIVE STUDY
Hironori Fujiwara, Yaoyu Han, Ken Ebihara, Suresh Awale, Ryota Araki, Takeshi Yabe, Kinzo Matsumoto
BACKGROUND: Our previous studies demonstrated that post-weaning social isolation (ISO) in mice induces behavior abnormalities such as deficits of sociability- and attention-like behaviors. These deficits can be attenuated by methylphenidate (MPH), a drug used for attention deficit hyperactivity disorder (ADHD), suggesting that ISO mice offer a potential animal model of comorbid developmental disorder with ADHD and autism spectrum disorder symptoms. This study investigated the effects of Kampo formulae, yokukansan (YKS) and keishito (KST), on the neuropsychiatric symptoms of ISO mice to clarify the therapeutic or preventive/delaying potential of these formulae for the treatment of neurodevelopmental disorders...
April 4, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28373204/dtb-select-4-april-2017
#16
(no author information available yet)
Renal function monitoring of ACE inhibitors/AIIRAs ● Combating falsified medicines ● NHS England issues guidelines on conflicts of interest ● C difficile control interventions and fluoroquinolone prescribing ● NHS Scotland booklet for young people with autism ● Accuracy of asthma diagnosis in adults ● Continuity of care and reduced hospital admissions ● Screen and treat approaches for diabetes prevention.
April 3, 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28357154/vaccine-hesitancy-in-search-of-the-risk-communication-comfort-zone
#17
Joshua Greenberg, Eve Dubé, Michelle Driedger
INTRODUCTION: This paper reports the findings of a national online survey to parents of children aged 5 and younger. The objectives of the study were to assess parental understanding of childhood immunizations, identify sources of information that they trust for vaccine-related content, assess where parents with young children stand on the key issues in the public debate about vaccination, and identify which risk communication messages are most effective for influencing the behaviours of vaccine hesitant parents...
March 3, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28335879/are-social-and-communication-difficulties-a-risk-factor-for-the-development-of-social-anxiety
#18
Hannah Pickard, Fruhling Rijsdijk, Francesca Happé, William Mandy
OBJECTIVE: Social anxiety (SA) is a common condition associated with social and communication (SC) difficulties in typically developing young people, as well as those with autism spectrum disorder (ASD). Whether SC difficulties place children at risk for developing SA is unclear. Using a longitudinal design, the present study aimed to disentangle the relationship between SA symptoms and SC difficulties using a population-based sample of 9,491 children from the Avon Longitudinal Study of Parents and Children (ALSPAC)...
April 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28326463/relationship-between-selenium-lead-and-mercury-in-red-blood-cells-of-saudi-autistic-children
#19
Afaf El-Ansary, Geir Bjørklund, Alexey A Tinkov, Anatoly V Skalny, Hussain Al Dera
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that can cause significant social, communication and behavioral challenges. Environmental contribution to ASD is due in large part to the sensitivity of the developing brain to external exposures such as lead (Pb), and mercury (Hg) as toxic heavy metals or due to a poor detoxification ability as the phenotype of this disorder. Selenium (Se) as an antioxidant element that counteracts the neurotoxicity of Hg, and Pb, presumably through the formation of nontoxic complexes...
March 21, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28316773/vitamin-d-treatment-during-pregnancy-prevents-autism-related-phenotypes-in-a-mouse-model-of-maternal-immune-activation
#20
Stephanie Vuillermot, Wei Luan, Urs Meyer, Darryl Eyles
BACKGROUND: Prenatal exposure to infection is a recognized environmental risk factor for neuropsychiatric disorders of developmental origins such as autism or schizophrenia. Experimental work in animals indicates that this link is mediated by maternal immune activation (MIA) involving interactions between cytokine-associated inflammatory events, oxidative stress, and other pathophysiological processes such as hypoferremia and zinc deficiency. Maternal administration of the viral mimic polyriboinosinic-polyribocytidylic acid (poly(I:C)) in mice produces several behavioral phenotypes in adult offspring of relevance to autism spectrum disorder (ASD) and other neurodevelopmental disorders...
2017: Molecular Autism
keyword
keyword
72344
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"