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Carmen Mesas Burgos, Björn Frenckner
BACKGROUND: Improvements in the clinical management of CDH have led to overall improved reported result from single institutions. However, population-based studies have highlighted a hidden mortality. AIM: To explore the incidence in Sweden and to address the hidden mortality for CDH during a 27-year period in a population-based setting. MATERIALS AND METHODS: This is a population based cohort study that includes all patients diagnosed with CDH that were registered in the National Patient Register, the Medical Birth Register, the Register of Congenital Malformations and the Register for Causes of Death between 1987 and 2013...
September 23, 2016: Journal of Pediatric Surgery
Zahra Dehbashi, Mahmood Moosazadeh, Mahdi Afshari
BACKGROUND: Each year, more than forty million abortions are occurred whole of the world. Misoprostol is a prostaglandin analogue with a strong uterotonic effect. The present study aimed to compare the efficacy of Misoprostol in first trimester abortion through two sublingual and vaginal routes of administration. METHODS: This randomized clinical trial was conducted on 52 consecutive women in first trimester candidate for pregnancy termination because of fetal IUFD or missed abortion in sonography reports...
July 24, 2016: Materia Socio-medica
Sandra Larsen, Joanna Dobbin, Oliver McCallion, Anne Eskild
INTRODUCTION: Vaginal delivery is recommended after intrauterine fetal death (IUFD). However, little is known about the risk of shoulder dystocia in these deliveries. We studied whether IUFD increases the risk of shoulder dystocia at delivery. MATERIAL AND METHODS: In this population-based register study using the Medical Birth registry of Norway, we included all singleton pregnancies with vaginal delivery of offspring in cephalic presentation in Norway during the period 1967-2012 (n=2 266 118)...
September 30, 2016: Acta Obstetricia et Gynecologica Scandinavica
Whitney A McCarthy, Edwina J Popek
Fetal anemia and hydrops may be caused by parvovirus B19 infection and maternal alloimmunization to RhD with subsequent hemolytic disease of the fetus and newborn. The use of intrauterine transfusion over the last few decades has dramatically improved outcomes. Prior literature has extensively documented placental changes associated with untreated parvovirus infection and RhD HDFN in intrauterine fetal demises (IUFD) and pre-term births; however, histopathologic changes in term placentas from term infants treated with IUT have not been reported...
September 19, 2016: Pediatric and Developmental Pathology
Oner Aynıoglu, Hatice Isik, Ahmet Sahbaz, Husnu Alptekın, Ulku Bayar
OBJECTIVES: Recurrent pregnancy loss (RPL) is a serious problem in the reproductive age women. We aimed to study the role of anticoagulant therapy on pregnancy complications and perinatal outcomes in pregnant patients with histories of RPL. MATERIAL AND METHODS: One hundred fifty-three pregnants, with RPL history and thrombophilia positivity, were grouped into two as 89 treated with anticoagulant therapy and 64 non-treated. Treated and untreated groups were compared for pregnancy complications, delivery weeks, abortion rates, fetal birth weights, APGAR scores, live birth rates, and newborn intensive care admission rates...
2016: Ginekologia Polska
Qing-Qing Luo, Li Zou, Hui Gao, Yan-Fang Zheng, Yin Zhao, Wei-Yuan Zhang
AIM: To assess pregnancy outcomes in pregnancies with idiopathic polyhydramnios at term. METHODS: We conducted a retrospective cohort study of 106 225 term pregnancies from 37 hospitals in China. Maternal and fetal outcomes in pregnancies with idiopathic polyhydramnios were compared with pregnancies with normal amniotic fluid. The primary outcome was intra-uterine fetal death (IUFD). RESULTS: In all, 307 out of 106 225 (0.3%) had idiopathic polyhydramnios at term, 276 of which were mild and 31 of which were moderate-severe...
September 14, 2016: Journal of Maternal-fetal & Neonatal Medicine
Yukiko Chinen, Tadatsugu Kinjo, Hayase Nitta, Yui Kinjo, Hitoshi Masamoto, Yoichi Aoki
It was demonstrated that second- and third-trimester therapeutic termination of pregnancy (TOP) is feasible in cases with placenta previa. We report a 34-year-old woman with complex fetal malformations associated with placenta previa. An ultrasound examination at 21 weeks of gestation revealed fetal growth restriction (FGR) and complex fetal malformations associated with a placenta previa. After extensive information, the parents opted for careful observation. Thereafter, FGR gradually progressed and we observed arrest of end-diastolic velocity of the umbilical artery...
2016: Case Reports in Obstetrics and Gynecology
K Neykova, V Dimitrova, R Dimitrov, L Vakrilova
AIM: To analyze pregnancy outcome in patients who were on antithrombotic medication (AM) because of previous pregnancy with fetal intrauterine growth restriction (IUGR). MATERIALS AND METHODS: The studied group (SG) included 21 pregnancies in 15 women with history of previous IUGR. The patients were on low dose aspirin (LDA) and/or low molecular weight heparin (LMWH). Pregnancy outcome was compared to the one in two more groups: 1) primary group (PG) including the previous 15 pregnancies with IUGR of the same women; 2) control group (CG) including 45 pregnancies of women matched for parity with the ones in the SG, with no history of IUGR and without medication...
2016: Akusherstvo i Ginekologii︠a︡
Hend Shalaby, Reda Hemida, Hanan Nabil, Mohammad Ibrahim
BACKGROUND: Congenital anomalies of the kidney and urinary tract in the developing countries have a poor prognosis due to limited experience in antenatal and postnatal management. PATIENTS AND METHODS: A 3-year retrospective study was carried out from January 2011 to December 2013. The following data were collected and analyzed: maternal age, gravidity, parity, gestational age at diagnosis, and ultrasonography findings. Final diagnosis after birth, the performed surgeries, follow-up data, as well as survival at one year were also analyzed...
October 2016: Journal of Obstetrics and Gynaecology of India
Nada Aracic, Damir Roje, Ivana Alujevic Jakus, Marinela Bakotin, Vedran Stefanovic
PURPOSE: To assess the distribution of births and spontaneous abortions, first-trimester abortion (FTA) and mid-trimester abortion (MTA), in untreated (n=128) and low molecular weight heparin (LMWH) treated pregnancies (n=50) of the same women with inherited thrombophilias and adverse pregnancy outcome (APO) in previous pregnancies. We particularly investigated the impact of LMWH on reducing the pregnancy complications in two thrombophilia types, "Conventional" and "Novel". MATERIALS AND METHODS: 50 women with inherited thrombophilia (26 Conventional and 24 Novel) and APO in previous pregnancies were included in the study...
September 2016: Yonsei Medical Journal
William T Schnettler, Ary L Goldberger, Steven J Ralston, Madalena Costa
BACKGROUND: Visual non-stress test interpretation lacks the optimal specificity and observer-agreement of an ideal screening tool for intrauterine fetal demise (IUFD) syndrome prevention. Computational methods based on traditional heart rate variability have also been of limited value. Complexity analysis probes properties of the dynamics of physiologic signals that are otherwise not accessible and, therefore, might be useful in this context. OBJECTIVE: To explore the association between fetal heart rate (FHR) complexity analysis and subsequent IUFD...
August 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Sarah K Dotters-Katz, Whitney M Humphrey, Kayli L Senz, Vanessa R Lee, Brian L Shaffer, Aaron B Caughey
Objective This study aims to evaluate the perinatal and neonatal outcomes associated with prenatal diagnosis of 45,X, both with and without fetal cardiac anomalies. Study Design A retrospective cohort of singleton pregnancies in California, 2005 to 2008, using vital statistics and International Classification of Diseases, Ninth Revision data, identifying prenatally diagnosed 45,X. Outcomes included preterm delivery, preeclampsia, intrauterine fetal demise (IUFD), cesarean section, small for gestational age (SGA), neonatal death, and infant death...
October 2016: American Journal of Perinatology
Amber N Fontenot Ferriss, Laurin Weisenthal, Jeanelle Sheeder, Stephanie B Teal, Kristina Tocce
OBJECTIVE: To assess risk of hemorrhage during surgical evacuation for intrauterine fetal demise (IUFD). METHODS: We compared hemorrhage associated with surgical evacuation for IUFDs ≥14weeks to surgical evacuations for other indications. RESULTS: From 12/2005 to 4/2013, 477 in-hospital surgical evacuations met inclusion criteria (123 IUFD, 354 comparators). The groups were demographically similar. Hemorrhage occurred in 7.3% of IUFDs and 4...
June 22, 2016: Contraception
Leila Pourali, Sedigheh Ayati, Shahrzad Jelodar, Ahmadreza Zarifian, Mohammad Sobhan Sheikh Andalibi
INTRODUCTION: Regarding to the recent advances in assisted reproductive techniques (ART), twin and multiple pregnancies have increased during past years. OBJECTIVE: This study was performed to compare obstetrics and perinatal outcomes of dichorionic twin pregnancy following ART with spontaneous pregnancy. MATERIALS AND METHODS: In this cross-sectional study which was performed in Ghaem Hospital, Mashhad University of Medical Sciences, 107 dichorionic twin pregnancy were enrolled in two groups: spontaneous group (n=96) and ART group (n=31)...
May 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
Tania F Esakoff, Alyson Guillet, Aaron B Caughey
OBJECTIVE: Our goal was to determine whether pregnancy outcomes are worse in gestational diabetics with small for gestational age (SGA) than those without. METHODS: This was a retrospective cohort study of 114 199 pregnancies with gestational diabetes mellitus (GDM) in California, 6446 of which were complicated by SGA. SGA was defined as birth weight  < 10th percentile. Predictors included the presence or absence of SGA. Outcomes included respiratory distress syndrome (RDS), neonatal demise (NND), intrauterine fetal demise (IUFD), hypoglycemia and jaundice...
June 8, 2016: Journal of Maternal-fetal & Neonatal Medicine
Satoshi Ishikawa, Mamoru Morikawa, Takeshi Umazume, Takahiro Yamada, Hiromi Kanno, Emi Takakuwa, Hisanori Minakami
Causes of intrauterine fetal death (IUFD) are uncertain in most placental mesenchymal dysplasia (PMD) cases. Our case showed high α-fetoprotein levels in the maternal circulation, markedly dilated subchorionic vessels, and neonatal hemoglobin concentration of 8.4 g/dL, suggesting that fetal anemia may explain some adverse outcomes in PMD pregnancies.
May 2016: Clinical Case Reports
Maria Angela Rustico, Dario Consonni, Mariano Lanna, Stefano Faiola, Vito Schena, Barbara Scelsa, Paola Introvini, Andrea Righini, Cecilia Parazzini, Gianluca Lista, Francesco Barretta, Enrico Ferrazzi
OBJECTIVE: To describe changes in the umbilical artery (UA) Doppler flow of monochorionic diamniotic (MC DA) twins with selective intrauterine growth restriction (sIUGR), to correlate Doppler findings with pregnancy course and perinatal outcome, to report postnatal follow up. METHODS: Retrospective study of 140 MC DA twins with sIUGR. UA end-diastolic flow, defined as pattern Type I (persistently positive), Type II (persistently absent or persistently reversed), and Type III (intermittent) was recorded at first examination and monitored weekly until double or single fetal death, bipolar cord coagulation, or delivery...
April 7, 2016: Ultrasound in Obstetrics & Gynecology
Assaad Kesrouani, Alain Daher, Ali Maoula, Elie Attieh, Sami Richa
OBJECTIVE: Evaluate the outcome of prenatally diagnosed nuchal cord. METHODS: A retrospective study on all cases of prenatally diagnosed nuchal cord. Study end points were gestational age at delivery, intrapartum fetal heart rate (FHR) abnormalities, mode of delivery, intrauterine fetal growth retardation (IUGR), intrauterine fetal demise (IUFD), and the rate of labor induction. RESULTS: This study included 44 cases; 86% were diagnosed at second trimester scan, confirmed by Color Doppler and 3D ultrasound...
April 28, 2016: Journal of Maternal-fetal & Neonatal Medicine
Gil Gutvirtz, Asnat Walfisch, Ofer Beharier, Eyal Sheiner
OBJECTIVE: To determine whether an isolated single umbilical artery (iSUA) is an independent risk factor for perinatal mortality in term neonates with normal estimated fetal weight (EFW) prior to delivery. METHOD: A population-based study was conducted, including all deliveries occurring between 1993 and 2013, in a tertiary medical center. Pregnancies with and without iSUA were compared. Multiple gestations, chromosomal, and structural abnormalities were excluded from the cohort...
April 5, 2016: Archives of Gynecology and Obstetrics
Catherine A Bigelow, Christina M Cinelli, Sarah E Little, Carol B Benson, Mary C Frates, Louise E Wilkins-Haug
OBJECTIVES: To report our contemporary experience with PUBS, including indications and complications, stratified by the presence of hydrops fetalis. STUDY DESIGN: All PUBS performed from 1988 to 2013 at a single tertiary care center were identified using a comprehensive ultrasound database. We recorded patient demographics, relevant obstetric, fetal and neonatal data, indication for and success of PUBS and any complications. Data were analyzed using SAS, version 9...
May 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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