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https://www.readbyqxmd.com/read/28579628/a-review-of-intra-uterine-foetal-deaths-at-the-cape-coast-teaching-hospital
#1
Vincent Adjetey, Derek A Tuoyire, Adjoa B Bonsu
AIM: To estimate the rate of IUFD/Stillbirths (SB). STUDY DESIGN: This is a retrospective review of delivery suite records from Jan 1 2013 to Dec 31 2014. METHODS: Study was undertaken at the Cape Coast Teaching Hospital (CCTH) in the Central region of Ghana. All pregnant women who had their babies at the delivery suite of CCTH have their records hand written in Ghana health service approved and distributed delivery records book. We identified all patients with IUFD/SB from this delivery suite record book which is kept on the delivery suite...
December 2016: Ghana Medical Journal
https://www.readbyqxmd.com/read/28509322/polymorphic-variants-of-genes-involved-in-choline-pathway-and-the-risk-of-intrauterine-fetal-death
#2
Krzysztof Drews, Agata Różycka, Magdalena Barlik, Andrzej Klejewski, Grażyna Kurzawińska, Hubert Wolski, Marian Majchrzycki, Agnieszka Gryszczyńska, Adam Kamiński, Agnieszka Seremak-Mrozikiewicz
OBJECTIVES: Choline and folate metabolism disturbances may be involved in the occurrence of intrauterine fetal death (IUFD). The proper activity of this metabolism could be determined by genetic variants involved in choline pathway e.g. CHKA (gene encoding choline kinase α), PCYT1A (gene encoding CCTα) and CHDH (gene encoding choline dehydrogenase). Our study aimed at determining the genotype and allele frequencies of CHKA rs7928739, PCYT1A rs712012, PCYT1A rs7639752, CHDH rs893363 and CHDH rs2289205 polymorphisms in mothers with IUFD occurrence...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28494269/medical-conditions-associated-with-recurrent-miscarriage-is-bmi-the-tip-of-the-iceberg
#3
Mushi J Matjila, Anne Hoffman, Zephne M van der Spuy
BACKGROUND: In contrast to sporadic miscarriage, recurrent miscarriage (RM) is a rare entity which affects 1% of couples attempting conception. It is distressing for couples and healthcare professionals as the aetiology is unclear with limited treatment options. Apart from anti-phospholipid syndrome (APS), the strength of associations between RM and commonly investigated endocrine, autoimmune, thrombophilic and uterine structural abnormalities remains uncertain and variable. OBJECTIVES: To assess the prevalence of commonly investigated medical conditions associated with RM...
July 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28405983/reproductive-health-in-systemic-lupus-erythematosus-an-experience-from-government-hospital-in-western-india
#4
Rushabh Kothari, Amruta Digole, Sandip Kamat, Y S Nandanwar, Yojana Gokhale
AIM: Systemic lupus erythematosus is an autoimmune disease which affects the reproductive health of women pertaining to disease or its treatment. However, Indian data is limited. Objective is to study menstrual disturbances and maternal and fetal outcome during pregnancy in SLE patients. METHODS: This retrospective and prospective observational study was conducted for a period of 18 months from March 2012 to September 2013 in a tertiary care hospital in Mumbai. The study included serial recruitment of SLE patients fulfilling inclusion criteria...
December 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28236631/causes-of-intrauterine-fetal-death-are-changing-in-recent-years
#5
Hiroko Takita, Junichi Hasegawa, Masamitsu Nakamura, Tatsuya Arakaki, Tomohiro Oba, Ryu Matsuoka, Akihiko Sekizawa
OBJECTIVE: To investigate, how causes of intrauterine fetal death (IUFD) have changed in recent years with the advancement of prenatal diagnosis at a single perinatal center in Japan. METHODS: Medical records were retrospectively reviewed for all cases of IUFDs that occurred between 2001 and 2014. The most commonly associated causes of fetal deaths were compared between 2001-2007 and 2008-2014. RESULTS: The number of IUFD after 20 weeks' gestation/all deliveries in our center was 38/6878 cases (0...
February 25, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28159120/women-s-experiences-of-stillbirth-in-somaliland-a-phenomenological-description
#6
Hodan Mohamoud Osman, Jama Ali Egal, Jonah Kiruja, Fatumo Osman, Ulrika Byrskog, Kerstin Erlandsson
BACKGROUND: Low- and middle-income countries in Africa have the highest rates of stillbirths in the world today: as such, the stories of the grief of these women who have had a stillbirth in these settings need to be told and the silence on stillbirth needs to be broken. In an attempt to fill this gap, the aim of this study was to describe the experiences of Muslim Somali mothers who have lost their babies at birth. METHOD: Qualitative interviews with ten Somali women one to six months after they experienced a stillbirth...
March 2017: Sexual & Reproductive Healthcare: Official Journal of the Swedish Association of Midwives
https://www.readbyqxmd.com/read/28116109/a-case-of-a-surviving-co-twin-diagnosed-with-porencephaly-and-renal-hypoplasia-after-a-single-intrauterine-fetal-death-at-21-weeks-of-gestation-in-a-monochorionic-monoamniotic-twin-pregnancy
#7
Hidenori Machino, Takayuki Iriyama, Toshio Nakayama, Atsushi Komatsu, Takeshi Nagamatsu, Yutaka Osuga, Tomoyuki Fujii
Monochorionic monoamniotic (MM) twin pregnancy carries a high risk of intrauterine fetal death (IUFD). Single IUFD in an MM twin pregnancy prior to 22 weeks of gestation has been reported to be strongly correlated with double twin demise. To our knowledge, there are no case reports on the natural course of a surviving co-twin in an MM twin pregnancy resulting in live birth after a single IUFD prior to 22 weeks of gestation. Here, we report a case of a surviving co-twin, after a single IUFD at 21 weeks of gestation in a MM twin pregnancy, with an antenatal diagnosis of renal hypoplasia and severe neurological damage leading to porencephaly, and live birth at 36 weeks of gestation...
January 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28078779/association-between-zika-virus-and-fetopathy-a-prospective-cohort-study-in-french-guiana
#8
L Pomar, G Malinger, G Benoist, G Carles, Y Ville, D Rousset, N Hcini, C Pomar, A Jolivet, V Lambert
OBJECTIVE: To establish the incidence of fetal central nervous system (CNS) anomalies (including microcephaly), signs of congenital infection and fetal loss in pregnant women infected with Zika virus (ZIKV) and non-infected pregnant women in western French Guiana. METHODS: This prospective cohort study was conducted between 1 January and 15 July 2016. We evaluated and compared clinical and fetal ultrasound examinations of 301 pregnant women with biological confirmation of ZIKV infection and 399 pregnant women who were negative for ZIKV infection...
January 12, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28076991/type-2-diabetes-mellitus-does-prenatal-care-affect-outcomes
#9
Allison J Allen, Jonathan M Snowden, Bernard Lau, Yvonne Cheng, Aaron B Caughey
OBJECTIVE: To determine if prenatal care affects adverse perinatal outcomes in pregnant women with Type-2 diabetes mellitus (T2DM). STUDY DESIGN: This was a retrospective cohort study of pregnant women with pregestational diabetes mellitus pregnancies in the state of California between 1997 and 2006, using vital statistics data linked to birth certificates. Women were stratified by time of presentation to care and we compared those who presented in the first trimester, third trimester, and those who had no prenatal care prior to delivery...
February 15, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27935148/customized-versus-population-based-growth-charts-to-identify-neonates-at-risk-of-adverse-outcomes-a-systematic-review-and-bayesian-meta-analysis-of-observational-studies
#10
REVIEW
Giuseppe Chiossi, Claudia Pedroza, Maged M Costantine, Van Thi Thanh Truong, Giancarlo Gargano, George R Saade
OBJECTIVE: To compare the effectiveness of customized versus population-based growth charts for prediction of adverse pregnancy outcomes. METHODS: we searched MEDLINE, http://ClinicalTrials.gov and the Cochrane library up to May 31(st) 2016 to identify interventional and observational studies comparing adverse outcomes among large (LGA) and small (SGA) for gestational age neonates, when classified with customized versus population-based growth charts. We studied perinatal mortality and NICU admission among both SGA and LGA neonates, IUFD and neonatal mortality among SGA, shoulder dystocia, 3(rd) and 4(th) degree perineal lacerations, as well as neonatal hypoglycemia among LGA...
December 9, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27806559/investigation-the-effects-of-metformin-versus-insulin-on-neonatal-and-maternal-outcomes-in-women-with-gestational-diabetes-mellitus-a-randomized-clinical-trail
#11
Mahin Najafian, Mojgan Barati, Sara Masihi, Ailin Fardipor
The aim of this study was to evaluate the effectiveness of metformin versus insulin in the glycemic control and to investigate the maternal and neonatal outcomes in in women with gestational diabetes mellitus. Pregnant women with gestational diabetes were randomized to either receive metformin (n=70) or insulin (n=70). Inclusion criteria were singleton pregnancy, following healthy diet and performing exercise for at least one week without satisfactory blood glucose level, no risk factor contributing to lactic acidosis, and no anatomic and/or chromosome anomalies...
September 28, 2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27781322/stillbirth-and-intrauterine-fetal-death-contemporary-demographic-features-of-1000-cases-from-an-urban-population
#12
J Man, J C Hutchinson, M Ashworth, A E Heazell, I Jeffrey, N J Sebire
OBJECTIVES: Of 780 000 births annually in the UK, around 3300 are stillborn, a rate of approximately 4 per 1000 births. Traditional epidemiological associations are based on historic data. The aim of this study was to document contemporary demographic findings in a large series of > 1000 deaths in utero in London and compare these with national datasets. METHODS: From a dedicated database, including > 400 data fields per case, of fetal, infant and pediatric autopsies performed at Great Ormond Street Hospital and St George's Hospital, London, we extracted information on all intrauterine deaths, excluding terminations of pregnancy, from 2005 to 2013, inclusive...
November 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27781317/stillbirth-and-intrauterine-fetal-death-factors-affecting-determination-of-cause-of-death-at-autopsy
#13
J Man, J C Hutchinson, A E Heazell, M Ashworth, S Levine, N J Sebire
OBJECTIVES: There have been several attempts to classify cause of death (CoD) in stillbirth; however, all such systems are subjective, allowing for observer bias and making comparisons between systems challenging. This study aimed to examine factors relating to determination of CoD using a large dataset from two specialist centers in which observer bias had been reduced by classifying findings objectively and assigning CoD based on predetermined criteria. METHODS: Detailed autopsy reports from intrauterine deaths in the second and third trimesters during 2005-2013 were reviewed and findings entered into a specially designed database, in which CoD was assigned using predefined objective criteria...
October 25, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27771626/pregnancy-outcomes-regarding-maternal-serum-afp-value-in-second-trimester-screening
#14
Karolina Bartkute, Dalia Balsyte, Josef Wisser, Juozas Kurmanavicius
AIM: The aim of this study was to evaluate the predictive value of α-fetoprotein in maternal serum (MS-AFP) as a marker for diverse pregnancy outcomes. METHODS: The study was based on pregnancy and delivery data from 5520 women between 1999 and 2014 at University Hospital of Zurich (UHZ). INCLUSION CRITERIA: both MS-AFP and pregnancy outcome were known for the same pregnancy. Pregnancy outcomes and characteristics such as fetal malformation, intrauterine fetal death (IUFD) and intrauterine growth retardation as well as maternal age, weight before pregnancy, gestational age (GA) at delivery, newborn weight, length and head circumference were analyzed with respect to the MS-AFP value...
October 24, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27756175/pregnancies-complicated-by-both-preeclampsia-and-growth-restriction-between-34-and-37-weeks-gestation-are-associated-with-adverse-perinatal-outcomes
#15
Kathryn J Sharma, Tania F Esakoff, Alyson Guillet, Richard M Burwick, Aaron B Caughey
OBJECTIVE: To determine whether adverse outcomes were more common in late preterm pregnancies complicated by preeclampsia and growth restriction compared to those affected by preeclampsia alone. METHODS: This was a retrospective cohort study of 8927 singleton pregnancies with preeclampsia. Pregnancies with small for gestational age (SGA) neonates (birth weight <10th percentile) were compared to those appropriate for gestational age (AGA) neonates. Maternal outcomes included cesarean delivery (CD) rate, CD for fetal heart rate (FHR) abnormalities, abruption, postpartum hemorrhage (PPH), maternal transfusion, acute renal failure, and peripartum cardiomyopathy...
November 10, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27745705/addressing-the-hidden-mortality-in-cdh-a-population-based-study
#16
Carmen Mesas Burgos, Björn Frenckner
BACKGROUND: Improvements in the clinical management of CDH have led to overall improved reported result from single institutions. However, population-based studies have highlighted a hidden mortality. AIM: To explore the incidence in Sweden and to address the hidden mortality for CDH during a 27-year period in a population-based setting. MATERIALS AND METHODS: This is a population based cohort study that includes all patients diagnosed with CDH that were registered in the National Patient Register, the Medical Birth Register, the Register of Congenital Malformations and the Register for Causes of Death between 1987 and 2013...
April 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27698600/comparison-between-sublingual-and-vaginal-route-of-misoprostol-in-management-of-first-trimester-miscarriage-missing
#17
Zahra Dehbashi, Mahmood Moosazadeh, Mahdi Afshari
BACKGROUND: Each year, more than forty million abortions are occurred whole of the world. Misoprostol is a prostaglandin analogue with a strong uterotonic effect. The present study aimed to compare the efficacy of Misoprostol in first trimester abortion through two sublingual and vaginal routes of administration. METHODS: This randomized clinical trial was conducted on 52 consecutive women in first trimester candidate for pregnancy termination because of fetal IUFD or missed abortion in sonography reports...
July 24, 2016: Materia Socio-medica
https://www.readbyqxmd.com/read/27687568/intrauterine-fetal-death-and-risk-of-shoulder-dystocia-at-delivery
#18
Sandra Larsen, Joanna Dobbin, Oliver McCallion, Anne Eskild
INTRODUCTION: Vaginal delivery is recommended after intrauterine fetal death. However, little is known about the risk of shoulder dystocia in these deliveries. We studied whether intrauterine fetal death increases the risk of shoulder dystocia at delivery. MATERIAL AND METHODS: In this population-based register study using the Medical Birth Registry of Norway, we included all singleton pregnancies with vaginal delivery of offspring in cephalic presentation in Norway during the period 1967-2012 (n = 2 266 118)...
December 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27643761/persistence-of-villous-immaturity-in-term-deliveries-following-intrauterine-transfusion-for-parvovirus-b19-infection-and-rhd-associated-hemolytic-disease-of-the-fetus-and-newborn
#19
Whitney A McCarthy, Edwina J Popek
Fetal anemia and hydrops may be caused by parvovirus B19 infection and maternal alloimmunization to RhD with subsequent hemolytic disease of the fetus and newborn. The use of intrauterine transfusion over the last few decades has dramatically improved outcomes. Prior literature has extensively documented placental changes associated with untreated parvovirus infection and RhD HDFN in intrauterine fetal demises (IUFD) and pre-term births; however, histopathologic changes in term placentas from term infants treated with IUT have not been reported...
September 19, 2016: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/27629134/does-anticoagulant-therapy-improve-adverse-pregnancy-outcomes-in-patients-with-history-of-recurrent-pregnancy-loss
#20
Oner Aynıoglu, Hatice Isik, Ahmet Sahbaz, Husnu Alptekın, Ulku Bayar
OBJECTIVES: Recurrent pregnancy loss (RPL) is a serious problem in the reproductive age women. We aimed to study the role of anticoagulant therapy on pregnancy complications and perinatal outcomes in pregnant patients with histories of RPL. MATERIAL AND METHODS: One hundred fifty-three pregnants, with RPL history and thrombophilia positivity, were grouped into two as 89 treated with anticoagulant therapy and 64 non-treated. Treated and untreated groups were compared for pregnancy complications, delivery weeks, abortion rates, fetal birth weights, APGAR scores, live birth rates, and newborn intensive care admission rates...
2016: Ginekologia Polska
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