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Cerebral paresy

Monique C Minnema, Eva Kimby, Shirley D'Sa, Luc-Matthieu Fornecker, Stéphanie Poulain, Tom J Snijders, Efstathios Kastritis, Stéphane Kremer, Aikaterini Fitsiori, Laurence Simon, Frédéric Davi, Michael Lunn, Jorge J Castillo, Christopher J Patterson, Magali Le Garff-Tavernier, Myrto Costopoulos, Véronique Leblond, Marie-José Kersten, Meletios A Dimopoulos, Steven P Treon
Bing Neel syndrome is a rare disease manifestation of Waldenstrom macroglobulinemia that results from infiltration of the central nervous system by malignant lymphoplasmacytic cells. In this guideline, we describe the clinical symptoms, as well as the appropriate laboratory and radiological studies that can aid in the diagnosis. The presentation of Bing Neel syndrome may be very diverse, and include headaches, cognitive deficits, paresis, and psychiatric symptoms. The syndrome can present in patients with known Waldenstrom macroglobulinemia, even in the absence of systemic progression, but also in previously undiagnosed patients...
October 6, 2016: Haematologica
B Salazard, C Philandrianos, B Tekpa
"Palsy of the upper limb" in children includes various diseases which leads to hypomobility of the member: cerebral palsy, arthrogryposis and obstetrical brachial plexus palsy. These pathologies which differ on brain damage or not, have the same consequences due to the early achievement: negligence, stiffness and deformities. Regular entire clinical examination of the member, an assessment of needs in daily life, knowledge of the social and family environment, are key points for management. In these pathologies, the rehabilitation is an emergency, which began at birth and intensively...
October 2016: Annales de Chirurgie Plastique et Esthétique
Oscar Aze, Étienne Odjardias, Xavier Devillard, Barnabé Akplogan, Paul Calmels, Pascal Giraux
OBJECTIVE: Corticospinal tract damage is responsible for motor function impairment after stroke. However, many processes seem to induce muscle damage, which may limit rehabilitation achievement. To achieve a systematic literature review of human muscular modifications due to post-strike hemiplegia. This review considers structural (histological, biochemical) and physiological modifications and their functional consequences over 1 year after stroke. MATERIAL/PATIENTS AND METHODS: Literature search on PubMed, Embase and Cochrane databases for papers published before February 2016 combining the following keywords cerebral stroke, hemiplegic, atrophy, muscle structure, paresis, skeletal muscle fiber type, motor unit, oxidative stress, strength, motor control led to select forty articles...
September 2016: Annals of Physical and Rehabilitation Medicine
Vincent Luisier, Lalensia Weber, Daniel Fishman, Gérard Praz, Joseph-André Ghika, Didier Genoud, Joelle Nsimire Chabwine
BACKGROUND: The varicella zoster virus affects the central or peripheral nervous systems upon reactivation, especially when cell-mediated immunity is impaired. Among varicella zoster virus-related neurological syndromes, meningoradiculitis is an ill-defined condition for which clear management guidelines are still lacking. Zoster paresis is usually considered to be a varicella zoster virus-peripheral nervous system complication and treated with oral antiviral therapy. Yet in the literature, the few reported cases of herpes zoster with mild cerebral spinal fluid inflammation were all considered meningoradiculitis and treated using intravenous antiviral drugs, despite absence of systemic signs of meningitis...
September 26, 2016: BMC Research Notes
Anil Israni, Biswaroop Chakrabarty, Atin Kumar, Sheffali Gulati
Oculomotor nerve palsy can be due to varied causes that include diabetic neuropathy, myasthenia gravis, brainstem infarction, demyelinating conditions, and cerebral aneurysms. Among the aneurysmal causes of oculomotor nerve palsy, aneurysm of the posterior communicating artery has been observed to be the most common. Pupillary dysfunction is considered to be an important feature of aneurysmal oculomotor nerve paresis. A case of a 7-year-old boy with partial oculomotor nerve palsy with pupillary sparing is being reported here, the etiology of which is tortuous and ectatic distal internal carotid artery...
April 2016: Journal of Pediatric Neurosciences
James Prueter, Shawn M Stevens, Norberto Andaluz, Ravi N Samy
OBJECTIVE: In this patient report, Parsonage-Turner syndrome (acute brachial neuropathy) developed in our patient 1 day after resection of a vestibular schwannoma by a middle cranial fossa approach. Aiming to increase awareness of this rare disorder among neurotologists, we describe differential diagnoses, work-up, and management strategies. PATIENT: A 67-year-old man treated for vestibular schwannoma at a single tertiary referral center. INTERVENTION: Surgery for vestibular schwannoma, electromyography for confirmation of diagnosis, and physical therapy...
September 2016: Otology & Neurotology
Philipp Hendrix, Sebastian Senger, Christoph J Griessenauer, Andreas Simgen, Karsten Schwerdtfeger, Joachim Oertel
Navigated transcranial magnetic stimulation (nTMS) is a frequently used, non-invasive method to map the motor cortex. It is of great value in the preoperative workup of patients that suffer from motor eloquent brain lesions. Here, we present a single-center experience using preoperative nTMS in cortical motor eloquent lesions with emphasis on metastasis. All patients that underwent preoperative nTMS between June 2013 and January 2016 were evaluated. A total of 61 patients underwent nTMS before undergoing surgery for a motor eloquent brain lesion...
October 2016: Clinical Anatomy
Satoshi Tsutsumi, Juan Carlos Fernandez Miranda, Hideo Ono, Yukimasa Yasumoto
PURPOSE: The cisternal segments of the oculomotor nerve (OMN), which courses through the interpeduncular and oculomotor cisterns (OMC) have not been well delineated on neuroimages. The present study aimed to explore the cisternal segments of the OMN using magnetic resonance (MR) imaging. METHODS: A total of 92 patients were enrolled in this study. A constructive interference in steady-state sequence was performed in coronal and axial sections. RESULTS: On coronal images, cisternal portions of the OMN were entirely delineated in 97 % on the right and in 98...
July 20, 2016: Surgical and Radiologic Anatomy: SRA
Wang Yanhua, Shi Haishan, Hou Le, Zhong Xiaomei, Chen Xinru, Li Ling, Wu Zhangying, Zheng Dong, Zhang Yuefen, Tan Yan, Luo Xinni, Liu Sha, Ning Yuping
BACKGROUND: Neurosyphilis is caused by the invasion of Treponema pallidum into the central nervous system. General paresis (GP) is a type of neurosyphilis. The main manifestation of general paresis is dementia; however, this is different from the other types of dementia, which can be cured by adequate doses of penicillin in the early stage. Neurosyphilis is the "great imitator" because it can mimic many types of medical disorders. In addition, the manifestations of neurosyphilis are not typical...
2016: BMC Psychiatry
Nobuko Shiraiwa, Takashi Hosaka, Tsuyoshi Enomoto, Sachiko Hoshino, Akira Tamaoka, Norio Ohkoshi
A 79-year-old woman was admitted to our hospital because of prolonged impaired consciousness and right hemiparesis. She was treated for acute cerebral infarction because her brain magnetic resonance imaging showed extensive cortical lesions similar to acute infarction in diffusion weighted image, fluid attenuated inversion recovery, and T2 weighted images. On the fifth day, she had a focal seizure on the right side. A new lesion during imaging and electroencephalogram abnormality were observed at that time...
July 28, 2016: Rinshō Shinkeigaku, Clinical Neurology
Yongfeng Xu, Lan Liu
Ipsilateral hemiparesis is rare after a supratentorial stroke, and the role of reorganization in the motor areas of unaffected hemisphere is important for the rehabilitation of the stroke patients. In this study, we present a patient who had a subclinical remote infarct in the right pons developed ipsilateral hemiparesis and contralateral lower limb paresis caused by a new infarct in the left anterior cerebral artery territory. Our case suggests that the motor areas of the unaffected hemisphere might be reorganized after stroke, which is important for the rehabilitation of stroke patients...
July 2016: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
Alex Förster, Holger Wenz, Christoph Groden
The hyperintense acute reperfusion marker (HARM) has initially been described in acute ischemic stroke. The phenomenon is caused by blood-brain barrier disruption following acute reperfusion and consecutive delayed gadolinium enhancement in the subarachnoid space on fluid attenuated inversion recovery (FLAIR) images. Here we report the case of an 80-year-old man who presented with transient paresis and sensory loss in the right arm. Initial routine stroke MRI including diffusion- and perfusion-weighted imaging demonstrated no acute pathology...
2016: Case Reports in Radiology
Katharina Feil, Nicolina Boettcher, Franziska Lezius, Maximilian Habs, Tobias Hoegen, Katrin Huettemann, Carolin Muth, Ozan Eren, Florian Schoeberl, Andreas Zwergal, Otmar Bayer, Michael Strupp
OBJECTIVE: Additionally to the forearm rolling test to detect mild unilateral upper limb dysfunction, the bed cycling test (BCT) for detection of mild to moderate lower limb dysfunction was developed, evaluated and compared to the leg holding test. METHODS: In a prospective observer-blinded study, 60 patients with MRI/CT-proven focal cerebral hemisphere lesions and a mild to moderate unilateral paresis of the lower limb (graduated MRC 3-4/5), and 60 control persons with normal imaging were examined and filmed...
May 2016: Brain and Behavior
Sung-Hee Kim, Ziyoda Abdulkhaevna Akbarkhodjaeva, Ileok Jung, Ji-Soo Kim
Studying eye movements and vestibular function would provide insights into brain networks that are vulnerable in mitochondrial disorders. We sought eye movement and vestibular abnormalities in three Korean patients with a mitochondrial A3243G point mutation. The patients suffered from vertigo and imbalance during the stroke-like and seizure episodes from lesions involving the posterior cerebral cortex, which were accompanied by bilateral saccadic hypermetria and horizontal gaze-evoked nystagmus. Furthermore, two patients showed bilateral impairments of the vestibulo-ocular reflex during head impulses for the horizontal and posterior canals on both sides in the absence of caloric paresis...
July 2016: Neurological Sciences
Rohan Mahale, Anish Mehta, Aju Abraham John, Kiran Buddaraju, Abhinandan K Shankar, Mahendra Javali, Rangasetty Srinivasa
BACKGROUND: Seizures are the presenting feature of cerebral venous sinus thrombosis (CVST) in 12-31.9% of patients. 44.3% of patients have seizures in the early stage of the disease. Acute seizures (AS), refers to seizures which take place before the diagnosis or during the first 2 weeks afterward. OBJECTIVE: To report the predictors of acute seizures in cerebral venous sinus thrombosis (CVST). METHODS: 100 patients with CVST were included in the study...
July 2016: Epilepsy Research
Luis E Rodríguez-Tovar, Alicia M Nevárez-Garza, Armando Trejo-Chávez, Carlos A Hernández-Martínez, Gustavo Hernández-Vidal, Juan J Zarate-Ramos, Uziel Castillo-Velázquez
This is the first confirmed report of Encephalitozoon cuniculi (E. cuniculi) in farm meat rabbits located in Northern Mexico. Eighty young rabbits exhibited clinical signs of this zoonotic emerging disease, like torticollis, ataxia, paresis, circling, and rolling. Samples of brain, kidney, and liver were examined for histology lesions. For the first time the lesions caused by E. cuniculi were graded according to their severity (I, II, and III) and the size of the granulomas (Types A, B, and C). The main cerebral injuries were Grade III, coinciding with the presence of Type C granulomas...
2016: Journal of Pathogens
Christina Wayman, Denise A Duricki, Lisa A Roy, Barbara Haenzi, Shi-Yen Tsai, Gwendolyn Kartje, John S Beech, Diana Cash, Lawrence Moon
Stroke typically occurs in elderly people with a range of comorbidities including carotid (or other arterial) atherosclerosis, high blood pressure, obesity and diabetes. Accordingly, when evaluating therapies for stroke in animals, it is important to select a model with excellent face validity. Ischemic stroke accounts for 80% of all strokes, and the majority of these occur in the territory of the middle cerebral artery (MCA), often inducing infarcts that affect the sensorimotor cortex, causing persistent plegia or paresis on the contralateral side of the body...
2016: Journal of Visualized Experiments: JoVE
Sun-Ho Kim, Ji-Hyuk Park, Min-Ye Jung, Eun-Young Yoo
The purpose of the present study was to investigate the effects of electromyogram-triggered neuromuscular stimulation (EMG-stim) combined with task-oriented training (TOT) on upper extremity function in chronic stroke patients. Twenty chronic stroke patients were randomly assigned to either the intervention (n = 10) or control (n = 10) group. The intervention group conducted TOT with EMG-stim on the wrist and finger extensor of the affected arm for 30 minutes per day, 5 days per week, for 4 weeks...
June 2016: Occupational Therapy International
Barbara Landsmann, Daniela Pinter, Eva Pirker, Gerald Pichler, Walter Schippinger, Elisabeth M Weiss, Gabriel Mathie, Thomas Gattringer, Franz Fazekas, Christian Enzinger
PURPOSE: Previous studies demonstrated changes in sensorimotor network activation over time after stroke that have been interpreted as partly compensatory. Locomotor and balance trainings may improve both mobility and cognition even in chronic stroke and thereby impact on cerebral activation patterns. We here aimed at testing these assumptions in an exploratory study to inform subsequent larger intervention studies. PATIENTS AND METHODS: Eight patients (73.3±4...
2016: Clinical Interventions in Aging
Masaru Yanagihashi, Osamu Kano, Tomoya Terashima, Yuji Kawase, Sayori Hanashiro, Masahiro Sawada, Yuichi Ishikawa, Nobuyuki Shiraga, Ken Ikeda, Yasuo Iwasaki
BACKGROUND: Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive sterol storage disease caused by a mutated sterol 27-hydroxylase (CYP27A1) gene. Patients with typical CTX show neurological dysfunction including bilateral cataracts, paresis, cerebral ataxia, dementia, and psychiatric disorders, and magnetic resonance imaging (MRI) has revealed symmetrical lesions in the cerebellar white matter. CASE PRESENTATION: We report the case of a patient with late-onset spinal form CTX without brain lesion...
2016: BMC Neurology
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