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Uterine myoma

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https://www.readbyqxmd.com/read/29772408/hysteroscopic-myomectomy-of-a-large-submucosal-leiomyoma-with-novel-use-of-fluid-warming
#1
Tess Chase, Stephanie J Estes
Uterine fibroid size is often considered a limiting factor for considering the surgical approach to myomectomy. In this case, a 35-year-old woman presented with heavy menstrual bleeding and desire for fertility. An ultrasound three months prior could not assess the endometrium and suggested leiomyoma. Magnetic resonance imaging of the pelvis identified a fundal submucosal myoma measuring 6.8 × 7.1 × 3.5 cm. A planned staged hysteroscopic resection of the large submucosal fibroid with intramural component was achieved...
May 14, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29765929/gonadotropin-releasing-hormone-agonist-plus-aromatase-inhibitor-in-the-treatment-of-uterine-leiomyoma-in-near-menopause-patient-a-case-series-study
#2
Sanam Moradan
Objectives: There are many drugs for of symptomatic fibroids. Gonadotropin-releasing hormone (GnRH) agonists are the well known drugs. Also, aromatase inhibitors are effective. All published studies surveyed the effect of one of these two drugs. In this study as the first study decided to evaluate the effectiveness of the combination of GnRH agonists + aromatise inhibitor on the uterine fibroids. Methods: A cross-sectional prospective case series study was performed on 10 known cases of uterine fibroids late perimenopause, at least 3 myomas >5 cm, abnormal uterine bleeding and anemia due to fibroids, candidate for hysterectomy, no tendency to surgery...
April 2018: Journal of Menopausal Medicine
https://www.readbyqxmd.com/read/29750109/mediastinal-cysts-with-mullerian-differentiation
#3
Hiroyuki Miura, Jun Miura, Hiroshi Hirano
Mediastinal cysts with Mullerian differentiation are characterized by oestrogen receptor and progesterone receptor positive cell linings. We treated four patients with mediastinal cysts with Mullerian differentiation. All patients were female, from 46 to 52 years old, and had BMIs greater than 26 kg/m2 . All but one patient with cough were asymptomatic. The tumours were located in the paravertebral areas around the Th-1-7 vertebrae. There was no left/right difference. All of the preoperative diagnoses were bronchial cysts...
July 2018: Respirology Case Reports
https://www.readbyqxmd.com/read/29718788/vilaprisan-for-treating-uterine-fibroids
#4
Gian Benedetto Melis, Manuela Neri, Bruno Piras, Anna Maria Paoletti, Silvia Ajossa, Monica Pilloni, Maria Francesca Marotto, Valentina Corda, Alessandra Saba, Elena Giancane, Valerio Mais
Introduction The medical strategy to antagonize myoma size and related-symptoms is to reduce estrogen and progesterone activity on myomas. This can be obtained with the GnRH agonist (GnRHa) or with compounds that antagonize progesterone stimulatory activity on myomas. Selective progesterone receptor modulators (SPRMs) bind progesterone receptor (PR), leading to both agonist and antagonist effects. The result of SPRMs's action is tissue-specific and it depends on the particular affinity and strength of each SPRM...
May 2, 2018: Expert Opinion on Investigational Drugs
https://www.readbyqxmd.com/read/29705676/a-case-of-retroperitoneal-desmoid-type-fibromatosis-that-involved-the-unilateral-ureter-after-gynaecologic-surgery
#5
Hitomi Ono, Kensuke Hori, Lena Tashima, Tomohiko Tsuruta, Shin-Ichi Nakatsuka, Kimihiko Ito
INTRODUCTION: Desmoid-type fibromatosis represents a rare, benign, soft tissue tumour that is locally invasive with high recurrence potential. PRESENTATION OF CASE: We encountered a case of retroperitoneal desmoid-type fibromatosis in a 45-year-old woman who presented with chief complaints of stomach ache and vomiting. She underwent total abdominal hysterectomy and left salpingo-oophorectomy due to uterine myoma and a paroophoritic cyst at 42 years of age. Abdominal computed tomography showed a 5-cm left retroperitoneal tumour and severe hydronephrosis of the left kidney...
March 29, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29693945/anestheic-management-of-a-patient-with-intravenous-leiomyomatosis-extending-into-the-right-atrium
#6
Moe Kodama, Maiko Honma, Keisuke Shibukawa, Yasuhiro Kamada, Shoji Yanagiya, Michiaki Yamakage
Intravenous leiomyomatosis (IVL) is a condition in which leiomyoma originating from uterine myoma or intrauterine venous walls develops intravenously. A single-stage operation was planned by the departments of gynecology and cardiovascular surgery for a patient in which the IVL was extended across the tricuspid valve. It was possible to safely perform perioperative care with continued evaluation of the tumor position and intravascular volume through the use of transesophageal echocardiography (TEE). TEE can be useful in the intraoperative care of patients with intracardiac tumor extension as in this case...
May 2017: Masui. the Japanese Journal of Anesthesiology
https://www.readbyqxmd.com/read/29693017/prevention-and-management-of-complications-in-laparoscopic-myomectomy
#7
REVIEW
V Tanos, K E Berry, M Frist, R Campo, R L DeWilde
Myomectomy aims to preserve fertility, treat abnormal uterine bleeding, and alleviate pain. It should cause minimal damage to the endometrium, while being tolerable and durable, and reduce the incidence of myoma recurrence and complications including bleeding, hematoma, adhesions, and gravid uterus perforation. Training and experience are crucial to reduce complications. The surgical strategy depends on imaging information on the myomas. The position of the optical and secondary ports will determine the degree of ergonomic surgery performance, time and difficulty of myoma enucleation, and the suturing quality...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29673678/uterine-rupture-at-33rd-week-of-gestation-after-laparoscopic-myomectomy-with-signs-of-fetal-distress-a-case-report-and-review-of-literature
#8
Hiroyuki Yazawa, Kaoru Takiguchi, Fumihiro Ito, Keiya Fujimori
OBJECTIVE: We describe a case of uterine rupture (UR) during pregnancy after laparoscopic myomectomy (LM) and discuss the risk factors of UR. CASE REPORT: A 37-year-old woman with multiple myomas underwent laparoscopic myomectomy. Subserosal and intramural myomas were enucleated, and the myometrial wounds were repaired with single-layer suturing. Sixteen months after the operation, the patient conceived. At 33 weeks of gestation, emergency cesarean section was performed for the indication of fetal distress...
April 2018: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29673671/a-case-control-study-to-compare-the-outcome-of-women-treated-by-two-minimally-invasive-procedures-ultraminilaparotomy-myomectomy-and-laparoscopic-myomectomy
#9
Kuo-Chang Wen, Pi-Lin Sung, Wen-Hsun Chang, Huann-Cheng Horng, Yi-Jen Chen, Wen-Ling Lee, Peng-Hui Wang
OBJECTIVE: Ultraminilaparotomy myomectomy (UMLT-M with less 4 cm transverse skin incision) and conventional 3-port wound laparoscopic myomectomy (LM) approaches were proposed as alternative minimally invasive procedures in the management of women with symptomatic uterine myomas but few studies have compared the outcomes of both procedures. MATERIALS AND METHODS: Between January 2002 and December 2003, 71 patients undergoing UMLT-M were compared with those 71 women undergoing LM...
April 2018: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29620641/expression-and-prognostic-value-of-lactate-dehydrogenase-a-and-d-subunits-in-human-uterine-myoma-and-uterine-sarcoma
#10
Ke-Juan Song, Xiao-Ni Yu, Teng Lv, Yu-Long Chen, Yu-Chao Diao, Su-Li Liu, Yan-Kui Wang, Qin Yao
OBJECTIVE: This study aimed to determine the expression of lactate dehydrogenase (LDH)-A and LDH-D in patients with uterine myoma, cellular leiomyoma (CLM), and uterine sarcoma and to evaluate their prognostic significance. METHODS: Protein expression levels of LDH-A and LDH-D were determined in tissue samples from 86 patients (26 uterine myoma, 10 CLM, 50 uterine sarcoma) by immunohistochemistry and their associations with clinicopathologic parameters and outcomes were analyzed in patients with uterine sarcoma...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29604954/an-intramural-uterine-fibroid-became-submucosal-in-the-puerperium-proposed-probable-mechanism-a-case-report
#11
Elie Nkwabong
BACKGROUND: Vaginal prolapse of a large uterine fibroid is a rare phenomenon in a woman who delivered vaginally recently, given that this fibroid might have obstructed labor. The author presents a case report of a vaginally prolapsed large pedunculated submucosal uterine myoma in a woman with a recent uncomplicated vaginal delivery. CASE PRESENTATION: A 25-year-old black African woman had four intramural uterine fibroids of diameters 62 to 94 mm diagnosed in April 2013 with standard ultrasound scan...
April 1, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29574773/omega-3-fatty-acids-modulate-the-lipid-profile-membrane-architecture-and-gene-expression-of-leiomyoma-cells
#12
Md Soriful Islam, Clara Castellucci, Rosamaria Fiorini, Stefania Greco, Riccardo Gagliardi, Alessandro Zannotti, Stefano R Giannubilo, Andrea Ciavattini, Natale G Frega, Deborah Pacetti, Pasquapina Ciarmela
Uterine leiomyomas (fibroids or myomas) are the most common benign tumors of premenopausal women and new medical treatments are needed. This study aimed to determine the effects of omega-3 fatty acids on the lipid profile, membrane architecture and gene expression patterns of extracellular matrix components (collagen1A1, fibronectin, versican, or activin A), mechanical signaling (integrin β1, FAK, and AKAP13), sterol regulatory molecules (ABCG1, ABCA1, CAV1, and SREBF2), and mitochondrial enzyme (CYP11A1) in myometrial and leiomyoma cells...
March 25, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29564318/postoperative-outcomes-of-natural-orifice-transluminal-endoscopic-surgery-assisted-vaginal-hysterectomy-and-conventional-laparoscopic-assisted-vaginal-hysterectomy-a-comparative-study
#13
Seong Hee Kim, Chan Hee Jin, In Taek Hwang, Jun Sook Park, Jung Hwan Shin, Dae Woon Kim, Yong Soo Seo, Jee Nah Sohn, Yun Seok Yang
Objective: The present study aimed to determine the differences in outcomes between natural orifice transluminal endoscopic surgery-assisted vaginal hysterectomy (NAVH) and conventional laparoscopy-assisted vaginal hysterectomy (LAVH). Methods: We retrospectively reviewed the charts of patients who between July 2012 and September 2015, were diagnosed as having benign uterine disease such as uterine myoma, endometriosis, or adenomyosis and managed via NAVH or LAVH in a single-center (Eulji University Hospital)...
March 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29564309/current-medical-treatment-of-uterine-fibroids
#14
REVIEW
Geum Seon Sohn, SiHyun Cho, Yong Man Kim, Chi-Heum Cho, Mee-Ran Kim, Sa Ra Lee
Uterine fibroids (leiomyomas or myomas), benign monoclonal tumors, are the most common benign tumors in women. Heavy or prolonged menstrual bleeding, abnormal uterine bleeding, resultant anemia, pelvic pain, infertility, and/or recurrent pregnancy loss are generally associated with uterine fibroids. Although curative treatment of this tumor relies on surgical therapies, medical treatments are considered the first-line treatment to preserve fertility and avoid or delay surgery. The aim of this review is to provide available and emerging medical treatment options for symptomatic uterine fibroids...
March 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29562791/what-are-the-real-advantages-of-trans-endometrial-myomectomy-during-cesarean-delivery
#15
Andrea Tinelli, Antonio Malvasi, Alessandro Favilli, Sandro Gerli, Michael Stark
For more than a century, the enucleation of uterine myomas in cesarean section is performed by traditional means by incision of the serum of the uterus. In recent years, from the discovery of the myoma pseudocapsule and the advantages of its preservation, intracapsular myomectomy is also performed during caesarean section, basing on biological rationale and physiological outcomes. After reading the paper on trans-endometrial myomectomy during cesarean section, it has been displaced and doubtful about the scientific and biological efficacy of the proposed method...
March 21, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29514385/analysis-of-presurgical-uterine-artery-embolization-puae-for-very-large-uterus-myomatosus-patient-s-desire-to-preserve-the-uterus-case-series-and-literature-review
#16
Dirk Schnapauff, Manon Russ, Thomas Kröncke, Matthias David
PURPOSE:  Purpose of this paper to present results of a group of 21 consecutive patients who underwent uterine artery embolization (UAE) immediately before myomectomy. Surgical myomectomy can lead to a substantial blood loss in case of large or multiple tumors due to the hypervascularization of the tumors. This may lead to multiple blood transfusion or hysterectomy. In cases were the preservation of the uterus is demanded, pre-operative embolization could reduce the risk of substantial bleeding...
March 7, 2018: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/29494652/electrothermal-bipolar-vessel-sealing-device-ligasure%C3%A2-versus-conventional-diathermy-in-laparoscopic-myomectomy-a-propensity-matched-analysis
#17
Yi-Chieh Li, Angel Chao, Lan-Yang Yang, Hui-Yu Huang, Yi-Ting Huang, Hsin-Hong Kuo, Chin-Jung Wang
The purpose of this study was to compare the safety and efficacy of an electrothermal bipolar vessel sealing device (LigaSure™) and traditional electrical cauterization in laparoscopic myomectomy (LM). A total of 756 patients with symptomatic uterine myomas who underwent LM were reviewed retrospectively. A total of 225 cases of LM using LigaSure™ (LML group) were compared with a control group treated with traditional electrical cauterization (LME group) under propensity-matched analysis. Outcome measures for both groups were compared, such as operative time, blood loss (BL), complications, need for blood transfusion, hospital expenses, and hospital stay...
2018: PloS One
https://www.readbyqxmd.com/read/29486606/emerging-treatment-options-for-uterine-fibroids
#18
Jacques Donnez, Pablo Arriagada, Olivier Donnez, Marie-Madeleine Dolmans
Uterine fibroids (also known as leiomyomas or myomas) are the most common form of benign uterine tumors. Current management strategies involve mainly surgical interventions, but the choice of treatment is guided by patient age and desire to preserve fertility or avoid 'radical' surgery such as hysterectomy. Areas covered: There is growing evidence of the crucial role of progesterone pathways in the pathophysiology of uterine fibroids, leading to increasing use of selective progesterone receptor modulators (SPRMs) such as ulipristal acetate...
March 2018: Expert Opinion on Emerging Drugs
https://www.readbyqxmd.com/read/29483857/fertility-impairment-associated-with-uterine-fibroids-a-review-of-literature
#19
REVIEW
Marek Lisiecki, Maciej Paszkowski, Sławomir Woźniak
Uterine fibroids (also known as leiomyomas or myomas) are the most common benign tumors affecting reproductive organs in women. They are monoclonal tumors of the uterine smooth muscle, which spring from myometrium. It is estimated that they occur in 50-60% of the female population and rise to 70% by the age of 50. While mostly asymptomatic, myomas can be connected with several conditions, including abnormal bleeding with subsequent anemia, pelvic masses, pelvic pain, bulk symptoms, unfavorable impact on fertility and obstetric complications...
December 2017: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/29483851/ultrasonography-of-uterine-leiomyomas
#20
REVIEW
Andrzej Woźniak, Sławomir Woźniak
Uterine leiomyomas or uterine fibroids are the most common gynaecological tumours and occur in about 20-50% of women around the world. Ultrasonography (USG) is the first-line imaging examination in suspected fibroids and shows high sensitivity and specificity in diagnosing this condition. Ultrasound scans can be performed transvaginally (transvaginal scan - TVS) or transabdominally (transabdominal scan - TAS); both scans have advantages and limitations, but, in general, transvaginal sonography is superior to transabdominal sonography in most cases of pelvic pathology...
December 2017: Przeglad Menopauzalny, Menopause Review
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