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Uterine myoma

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https://www.readbyqxmd.com/read/27903466/preoperative-3-dimensional-magnetic-resonance-imaging-of-uterine-myoma-and-endometrium-prior-to-myomectomy
#1
Young Jae Kim, Kwang Gi Kim, Seung Hyun Lee, Byung Chul Kang, Sa Ra Lee
Uterine myomas are the most common gynecologic benign tumor affecting women of childbearing age, and myomectomy is the main surgical option to preserve the uterus and fertility. During myomectomy for women with multiple myomas, it is advisable to identify and remove as many as possible to decrease the risk of future myomectomies. With deficient preoperative imaging, gynecologists are challenged to identify the location and size of myomas and the endometrium, which in turn can lead to uterine rupture during future pregnancies...
November 26, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27900359/homozygous-inactivation-of-chek2-is-linked-to-a-familial-case-of-multiple-primary-lung-cancer-with-accompanying-cancers-in-other-organs
#2
Yoji Kukita, Jiro Okami, Noriko Yoneda-Kato, Ikuko Nakamae, Takeshi Kawabata, Masahiko Higashiyama, Junya Kato, Ken Kodama, Kikuya Kato
In clinical practice, there are a number of cancer patients with clear family histories, but the patients lack mutations in known familial cancer syndrome genes. Recent advances in genomic technologies have enhanced the possibility of identifying causative genes in such cases. Two siblings, an elder sister and a younger brother, were found to have multiple primary lung cancers at the age of 60. The former subsequently developed breast cancer and had a history of uterine myoma. The latter had initially developed prostate cancer at the age of 59 and had a history of colon cancer...
November 2016: Cold Spring Harbor Molecular Case Studies
https://www.readbyqxmd.com/read/27885348/should-prophylactic-anticoagulation-be-considered-with-large-uterine-leiomyoma-a-case-series-and-literature-review
#3
Mohamed A Satti, Carmen Paredes Saenz, Rubin Raju, Sierra Cuthpert, Abed Kanzy, Sina Abhari, John Hebert Iii, Frederico G Rocha
Introduction. Uterine leiomyomas, also called uterine fibroids or myomas, are the most common pelvic tumors in women. They are very rarely the cause of acute complications. However, when complications occur they cause significant morbidity and mortality. Thromboembolic disease has been described as a rare complication of uterine leiomyomas. DVT is a serious illness, sometimes causing death due to acute PE. Cases. We report a case series of 3 patients with thromboembolic disease associated with uterine leiomyoma at Hurley Medical Center, Flint, Michigan, during 2015 and conduct a literature review on the topic...
2016: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27873052/symptoms-of-uterine-myomas-data-of-an-epidemiological-study-in-germany
#4
Dolores Foth, Friedrich-Wilhelm Röhl, Cornelia Friedrich, Heike Tylkoski, Thomas Rabe, Thomas Römer, Ann Kitay, Hans-Joachim Ahrendt
PURPOSE: Currently, no reliable data are available concerning the type and frequency of symptoms in premenopausal women with uterine myomas. METHODS: 2296 women were examined by means of vaginal ultrasound for the presence of myomas in seven gynaecological outpatient departments in Germany. From this population, 1314 premenopausal women between the ages of 30 and 55 years were evaluated to determine the type and frequency of myoma-related symptoms and their relationship to anamnestic factors, and the number, size, and location of the myomas...
November 21, 2016: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/27862503/accuracy-of-saline-contrast-sonohysterography-in-detection-of-endometrial-polyps-and-submucosal-leiomyoma-in-women-at-reproductive-age-with-abnormal-uterine-bleeding-a-systematic-review-and-meta-analysis
#5
REVIEW
Carolina Abdou Bittencourt, Ricardo Dos Santos Simões, Wanderley Marques Bernardo, Luiz Fernando Portugal Fuchs, José Maria Soares Junior, Ayrton Roberto Pastore, Edmund Chada Baracat
OBJECTIVE: To analyze the diagnostic accuracy of 2D and 3D saline contrast sonohysterography compared to hysteroscopy in the detection of endometrial polyps and submucosal myomas in women during reproductive age with abnormal uterine bleeding. METHOD: A systematic review of diagnostic studies that compared saline contrast sonohysterography with hysteroscopy was conducted according to the PRISMA and SEDATE recommendations. Only studies that compared two and/or three dimensional saline contrast sonohysterography with hysteroscopy and anatomopathology were included...
November 15, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27858913/laparoscopic-management-of-a-twisted-ovarian-leiomyoma-in-a-woman-with-10-weeks-gestation-case-report-and-literature-review
#6
Myounghwan Kim
BACKGROUND: Primary leiomyoma of the ovary is a rare benign ovarian tumor that only seldom causes acute abdomen. CASE SUMMARY: A 35-year-old gravida 1, para 0 woman presented with a history of acute lower abdominal pain, and 10 weeks of amenorrhea. The patient's physical examination revealed abdominal tenderness, defense, and rebound. On ultrasonographic examination, a solid mass measuring 9.3 × 7.8 cm was detected adjacent to the uterine fundus. The mass was preoperatively diagnosed as a twisted pedunculated subserosal uterine myoma...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27817933/morcellation-worsens-survival-outcomes-in-patients-with-undiagnosed-uterine-leiomyosarcomas-a-retrospective-mito-group-study
#7
Francesco Raspagliesi, Giuseppa Maltese, Giorgio Bogani, Giovanni Fucà, Stefano Lepori, Pierandrea De Iaco, Myriam Perrone, Giovanni Scambia, Gennaro Cormio, Stefano Bogliolo, Alice Bergamini, Giuseppe Bifulco, Paolo Giovanni Casali, Domenica Lorusso
OBJECTIVE: To investigate the impact of morcellation on survival outcomes of patients affected by undiagnosed uterine sarcoma. METHODS: This is a retrospective study performed in 8 referral centers of MITO group. Data of women undergoing morcellation for apparent benign uterine myomas who were ultimately diagnosed with stage I uterine sarcoma on final pathology were compared with data of women who did not undergo morcellation. Uterine sarcoma included: leiomyosarcomas (LMS), smooth muscle tumors of uncertain malignant potential (STUMP), low-grade endometrial stromal sarcomas (LG-ESS) and undifferentiated uterine sarcomas (UUS)...
November 4, 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27800083/successful-myomectomy-in-early-pregnancy-for-a-large-asymptomatic-uterine-myoma-case-report
#8
Pawan Jhalta, Sonam Gialchhen Negi, Vikas Sharma
The decision of myomectomy is not usually taken by OBG specialist for uterine fibroids during pregnancy because of its complications which may become hazardous at times. This is why it is generally delayed until after delivery. The current case was a large, asymptomatic subserous uterine myoma diagnosed during pregnancy by ultrasound and successfully managed by antepartum myomectomy retaining the fetus alive in utero at 13 -14 weeks gestation. At term, the patient had spontaneous vaginal delivery of 3 kg male child...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27784616/the-role-of-leiomyomas-in-the-genesis-of-abnormal-uterine-bleeding-aub
#9
REVIEW
Ricardo Bassil Lasmar, Bernardo Portugal Lasmar
Abnormal uterine bleeding (AUB) is the major complaint in approximately one-third of gynecological visits in premenopausal women, and in >70% of appointments of perimenopausal and postmenopausal women. Uterine myoma is one of the main causes of AUB during menacme, especially when it is submucosal. The association of myoma and AUB may be related to several factors, from local alterations of angiogenic and vasoactive substances to changes in uterine contractility. The objective of this paper is to show the different associations of myoma and AUB...
October 1, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27769260/submucous-uterine-adenosarcoma-minimally-invasive-treatment
#10
H Krentel, R L De Wilde
BACKGROUND: Uterine adenosarcomas are rare malignant gynaecological tumours. Due to its submucous localization, they can be easily confound with benign tumours like endometrial polyps or submucous myomas. However, the treatment of uterine adenosarcomas requires an oncologic surgical approach. CASE PRESENTATION: In the following case report, we present the minimally invasive treatment of a uterine adenosarcoma by hysteroscopy and laparoscopy in a 37-year-old patient and discuss the special role of hysteroscopy in such cases...
October 21, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27769088/accuracy-of-transvaginal-ultrasonography-hysteroscopy-and-uterine-curettage-in-evaluating-endometrial-pathologies
#11
Miriam da Silva Wanderley, Miriam Monteiro Álvares, Maria de Fátima Brito Vogt, Lizandra Moura Paravidine Sazaki
Objective To evaluate the accuracy of transvaginal ultrasonography, hysteroscopy and uterine curettage in the diagnosis of endometrial polyp, submucous myoma and endometrial hyperplasia, using as gold standard the histopathological analysis of biopsy samples obtained during hysteroscopy or uterine curettage. Methods Cross-sectional study performed at the Hospital Universitário de Brasília (HUB). Data were obtained from the charts of patients submitted to hysteroscopy or uterine curettage in the period from July 2007 to July 2012...
October 2016: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/27757274/effects-of-herbal-medicine-on-human-uterine-tumor-bearing-nude-mice
#12
Mi Hyang Ohh, Seong Jin Kim, Jong Kwon Han, Sok Cheon Pak, Kew-Mahn Chee
AIM: Uterine leiomyomas are the most common benign uterine neoplasms associated with significant morbidity. Herbal formulas capable of restoring yin-yang balance by dispersing blood stasis may be useful for managing fibroid symptoms. MATERIALS AND METHODS: In this study, the antitumor properties of three herbs viz., Trogopterus xanthipes Milen-Edwards, Paeonia lactiflora Pallas, and Ulmus davidiana Planch were evaluated in nude mice injected intravenously with human malignant myomas...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27751409/a-retrospective-study-of-magnetic-resonance-guided-focused-ultrasound-ablation-for-uterine-myoma-in-taiwan
#13
Sheng-Ling Tung, Ting-Ywan Chou, Hung-Shi Tseng, Chi-Ming Lee
OBJECTIVE: To report our experiences with 40 patients who were treated with magnetic resonance-guided focused ultrasound surgery (MRgFUS) for uterine fibroids and their 6-month follow-up status. MATERIALS AND METHODS: A total of 40 patients with uterine fibroids underwent MRgFUS from January 2009 to November 2011. The Uterine Fibroid Symptoms and Quality of Life Questionnaire was used to determine the patients' Symptom Severity Scores (SSS) prior to and 6 months after treatment...
October 2016: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27740868/safety-of-treatment-of-uterine-fibroids-with-the-selective-progesterone-receptor-modulator-ulipristal-acetate
#14
Jacques Donnez, Olivier Donnez, Marie-Madeleine Dolmans
During the last decade, there has been increased emphasis on the role of progesterone in the promotion of fibroid growth, as well as heightened interest in modulating progesterone pathways by use of selective progesterone receptor modulators (SPRMs). Among them, ulipristal acetate (UPA) has proved its efficacy in the management of symptomatic myomas by controlling bleeding and inducing amenorrhea, and reducing the size of myomas in the majority of cases. Areas covered: In this review, we summarize published scientific studies exploring evidence of the safety of SPRMs and particularly UPA, a drug approved for the management of symptomatic uterine fibroids...
December 2016: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/27716434/oestrogen-induced-angiogenesis-and-implantation-contribute-to-the-development-of-parasitic-myomas-after-laparoscopic-morcellation
#15
Ben-Shian Huang, Muh-Hwa Yang, Peng-Hui Wang, Hsin-Yang Li, Teh-Ying Chou, Yi-Jen Chen
BACKGROUND: Iatrogenic parasitic myomas (PMs), caused by intra-corporeal power morcellation during laparoscopy is gradually increasing. However, the pathogenesis and medical treatment of PMs remain largely unelucidated. METHODS: Laparoscopically-induced PM xenografted mouse model was conducted by xenografting human uterine myoma fragments into the abdominal cavity of SCID mice and hormonal manipulation was performed using this mouse model to demonstrate the role of oestrogen in the development of implanted PMs...
October 6, 2016: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/27679378/low-dose-mifepristone-versus-placebo-to-treat-uterine-myoma-a-double-blind-randomized-clinical-trial
#16
C Liu
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27679034/latrogenic-parasitic-myomas-the-real-long-term-complication-of-laparoscopic-uterine-morcellation-diagnostic-management-and-preventing-rules
#17
B Rabischong, C Compan, R Botchorishvili, N Bourdel, M Canis
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27679018/the-importance-of-the-accurate-diagnostic-preoperational-magnetic-resonance-imaging-mri-examinations-review-of-1059-cases-that-undergoing-laparoscopic-surgery-for-diagnosed-benign-uterine-myoma
#18
M Yabuta, Y Kishi, N Koike, M Yamaguchi, F Taniguchi
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27678973/hysteroscopic-myomectomy-after-uterine-embolization-in-large-sized-submucosal-myoma
#19
J Namkung, M Kim
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27669395/a-selective-serotonin-5-ht1b-receptor-inhibition-suppresses-cells-proliferation-and-induces-apoptosis-in-human-uterine-leiomyoma-cells
#20
Nilgun Gurbuz, Mehmet Resit Asoglu, Ahmed A Ashour, Salama Salama, Gokhan S Kilic, Bulent Ozpolat
OBJECTIVE: Uterine leiomyomas (fibroids or myomas) are the most common pelvic tumor in women with about 70% lifetime incidence rate. Currently, the only definitive treatment is surgery, causing undesirable side effects and negative impact on women's quality of life, reproductive ability, and a substantial impact on healthcare costs. Therefore, curative medical treatments are needed to be developed. In this study, we investigated the impact of serotonin receptor 5-HT1B on cell proliferation and survival in human uterine leiomyoma cells (huLM)...
August 10, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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