Hong-Liang Su, Jie Zhu, Yan-Jiong Chen, Na Zhao, Wei Han, Yong-Hui Dang, Ming Xu, Teng Chen
Levo-tetrahydropalmatine (l-THP), as an alkaloid purified from the traditional Chinese herbal medicine Corydalis and Stephania, has been widely used to produce many traditional Chinese herbal preparations. The effect of l-THP on methamphetamine-induced reward learning still remains unclear although it has been proved to be effective on treating allodynia and drug addiction. This experiment has been designed to examine the effect of l-THP on the acquisition, expression, extinction, and reinstatement of methamphetamine-induced conditioned place preference (CPP) in mice...
June 13, 2013: Physiology & Behavior