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https://www.readbyqxmd.com/read/28086987/a-systematic-review-and-meta-analysis-of-the-seroprevalence-of-toxoplasma-gondii-in-cats-in-mainland-china
#1
Huan Ding, Yu-Meng Gao, Yao Deng, Poppy H L Lamberton, Da-Bing Lu
BACKGROUND: Toxoplasmosis is caused by Toxoplasma gondii which can infect all warm-blooded animals. As the most common feline definitive host, cats play a vital role in the transmission of T. gondii. However, national estimates of the seroprevalence of T. gondii in cats in mainland China are lacking, and therefore a systematic review and meta-analysis were performed to provide insight into national environmental transmission levels and potential transmission to humans. METHODS: Studies published up until July 1, 2016, on T...
January 13, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28066825/a-blinded-randomised-placebo-controlled-trial-investigating-the-efficacy-of-morphine-analgesia-for-procedural-pain-in-infants-trial-protocol
#2
Rebeccah Slater, Caroline Hartley, Fiona Moultrie, Eleri Adams, Ed Juszczak, Richard Rogers, Jane E Norman, Chetan Patel, Kayleigh Stanbury, Amy Hoskin, Gabrielle Green
Infant pain has both immediate and long-term negative consequences, yet in clinical practice it is often undertreated. To date, few pain-relieving drugs have been tested in infants. Morphine is a potent analgesic that provides effective pain relief in adults, but there is inconclusive evidence for its effectiveness in infants. The purpose of this study is to establish whether oral morphine provides effective analgesia for procedural pain in infants. A blinded, placebo-controlled, parallel-group randomized, phase II, clinical trial will be undertaken to determine whether morphine sulphate administered orally prior to clinically-required retinopathy of prematurity (ROP) screening and heel lancing provides effective analgesia...
November 15, 2016: Wellcome Open Res
https://www.readbyqxmd.com/read/28040324/metabolomics-and-lipidomics-analyses-by-1-h-nuclear-magnetic-resonance-of-schizophrenia-patient-serum-reveal-potential-peripheral-biomarkers-for-diagnosis
#3
Ljubica Tasic, João G M Pontes, Michelle S Carvalho, Guilherme Cruz, Carolines Dal Mas, Sumit Sethi, Mariana Pedrini, Lucas B Rizzo, Maiara Zeni-Graiff, Elson Asevedo, Acioly L T Lacerda, Rodrigo A Bressan, Ronei Jesus Poppi, Elisa Brietzke, Mirian A F Hayashi
Using (1)H NMR-based metabolomics in association to chemometrics analysis, we analyzed here the metabolic differences between schizophrenia patients (SCZ) compared to healthy controls (HCs). HCs and SCZ patients underwent clinical interview using the Structured Clinical Interview for DSM Disorders (SCID). SCZ patients were further assessed by Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale, Global Assessment of Functioning Scale (GAF), and Clinical Global Impressions Scale (CGI). Using the principal component analysis (PCA) and supervised partial least-squares discriminate analysis (PLS-DA) in obtained NMR data, a clear group separation between HCs and SCZ patients was achieved...
December 28, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/27996066/trapping-of-au-nanoparticles-in-a-microfluidic-device-using-dielectrophoresis-for-surface-enhanced-raman-spectroscopy
#4
Gabriela B Almeida, Ronei J Poppi, José A Fracassi da Silva
Dielectrophoresis (DEP) is the electrokinetic movement of non-charged particles when they are subjected to a non-uniform electric field. This is a growing area of research, which can be used for trapping, concentrating and separating different particles. Some work has been reported with the intention of trapping metal particles to optimize the surface enhanced Raman spectroscopy (SERS) effect. In this paper, we use DEP with insulating structures (iDEP) to generate a non-uniform electric field for trapping gold nanoparticles (AuNP)...
December 20, 2016: Analyst
https://www.readbyqxmd.com/read/27991536/genes-encoding-norcoclaurine-synthase-occur-as-tandem-fusions-in-the-papaveraceae
#5
Jing Li, Eun-Jeong Lee, Limei Chang, Peter J Facchini
Norcoclaurine synthase (NCS) catalyzes the enantioselective Pictet-Spengler condensation of dopamine and 4-hydroxyphenylacetaldehyde as the first step in benzylisoquinoline alkaloid (BIA) biosynthesis. NCS orthologs in available transcriptome databases were screened for variants that might improve the low yield of BIAs in engineered microorganisms. Databases for 21 BIA-producing species from four plant families yielded 33 assembled contigs with homology to characterized NCS genes. Predicted translation products generated from nine contigs consisted of two to five sequential repeats, each containing most of the sequence found in single-domain enzymes...
December 19, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27965463/ameloblastoma-rna-profiling-uncovers-a-distinct-non-coding-rna-signature
#6
Haleh Davanian, Anangi Balasiddaiah, Robert Heymann, Magnus Sundström, Poppy Redenström, Mikael Silfverberg, David Brodin, Matti Sällberg, Sven Lindskog, Carina Kruger Weiner, Margaret Chen
Ameloblastoma of the jaws remains the top difficult to treat odontogenic tumour and has a high recurrence rate. New evidence suggests that non-coding RNAs (ncRNAs) play a critical role in tumourgenesis and prognosis of cancer. However, ameloblastoma ncRNA expression data is lacking. Here we present the first report of ameloblastoma ncRNA signatures. A total of 95 ameloblastoma cases and a global array transcriptome technology covering > 285.000 full-length transcripts were used in this two-step analysis...
December 10, 2016: Oncotarget
https://www.readbyqxmd.com/read/27923690/dicranostiga-leptopodu-maxim-fedde-extracts-attenuated-ccl4-induced-acute-liver-damage-in-mice-through-increasing-anti-oxidative-enzyme-activity-to-improve-mitochondrial-function
#7
Deping Tang, Fang Wang, Jinzhou Tang, Aihong Mao, Shiqi Liao, Qin Wang
Dicranostiga Leptodu (Maxim.) fedde (DLF), a poppy plant, has been reported have many benefits and medicinal properties, including free radicals scavenging and detoxifying. However, the protective effect of DLF extracts against carbon tetrachloride (CCl4)-induced damage in mice liver has not been elucidated. Here, we demonstrated that DLF extracts attenuated CCl4-induced liver damage in mice through increasing anti-oxidative enzyme activity to improve mitochondrial function. In this study, the mice liver damage evoked by CCl4 was marked by morphology changes, significant rise in lipid peroxidation, as well as alterations of mitochondrial respiratory function...
January 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27901506/squamous-cell-carcinoma-in-a-wild-european-bullhead-cottus-gobio
#8
F Quaglio, V Zappulli, L Poppi, P Capovilla, F Capparucci, F Marino
A pharyngeal tumor was found in a wild European bullhead. The tumor mass appeared underneath the operculum and was bilobed. The major neoplastic component showed diffuse epithelial squamous differentiation. Crossmonn's trichrome allowed identification of connective tissues whereas no neoplastic cells were stained. Periodic acid-Schiff was negative within the mass, and Giemsa did not show any further diagnostic significance. Immunohistochemistry showed diffuse positive cytoplasmic staining of the neoplastic population with an anti-human pancytokeratin antibody...
November 22, 2016: Diseases of Aquatic Organisms
https://www.readbyqxmd.com/read/27895286/pyrolysis-of-poppy-capsule-pulp-for-bio-oil-production
#9
Derya Yeşim Hopa, Nazan Yılmaz, Oğuzhan Alagöz, Meltem Dilek, Ahmet Helvacı, Ümit Durupınar
The feasibility of biofuel production via the pyrolysis of poppy capsule pulp, the main waste product of Afyon Alkoloid Factory, was investigated. The poppy capsule pulp was shown to have a high volatile matter content (ca. 76%). Pyrolysis experiments were carried out in the temperature range 400-550°C (heating rate 18°C min(-1) and holding time 20 min) under a nitrogen atmosphere. The chemical components of the bio-oil were characterized by Fourier transform infrared spectrometry and gas chromatography-mass spectrometry...
December 2016: Waste Management & Research
https://www.readbyqxmd.com/read/27882891/a-comparative-mass-spectrometric-study-of-fatty-acids-and-metals-in-some-seed-extracts
#10
Sonia Niculina Suvar, R Bleiziffer, P Podea, A Iordache, C Voica, R Zgavarogea, M Culea
A major cause of cardiovascular diseases and cancer is diet content, so the optimization of micronutrients in food is very important. Omega-3 fatty acids supplementation for patients had beneficial effects on subjective global assessment score and metabolic profiles. Fatty acids content and the metal ions in different seeds (e.g. linseed, poppy, grape, hemp, nuts, pumpkin, sesame, watermelon, chia) recommended as food supplements, purchased on the Romanian market, were compared. Gas chromatography coupled to mass spectrometry (GC-MS) was used as an excellent technique for fatty acids identification and quantitation, and inductively coupled plasma mass spectrometer (ICP-MS) for analytical measurements of metals...
2016: European Journal of Mass Spectrometry
https://www.readbyqxmd.com/read/27848430/poppy-ambassador
#11
(no author information available yet)
Army nurse Ben Poku (pictured) is featuring in a Royal British Legion campaign for this year's poppy appeal.
November 9, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27837372/development-of-newly-sanguinarine-biosynthetic-capacity-in-in-vitro-rootless-shoots-of-argemone-mexicana-l-mexican-prickly-poppy
#12
Jorge Xool-Tamayo, Germán Serrano-Gamboa, Miriam Monforte-González, Gumersindo Mirón-López, Felipe Vázquez-Flota
OBJECTIVE: To analyze berberine and sanguinarine biosynthetic capacities of both in vitro shoot and root cultures of Argemone mexicana and tissues from entire plants at different developmental stages. RESULTS: Berberine and sanguinarine were equally distributed in roots and aerial tissues of developing plantlet whereas, in juvenile plants, sanguinarine was only detected in roots. This alkaloid distribution was consistent with that of biosynthetic transcripts in juvenile plants...
November 11, 2016: Biotechnology Letters
https://www.readbyqxmd.com/read/27830833/noscapine-targets-egfr-p-tyr1068-to-suppress-the-proliferation-and-invasion-of-mg63-cells
#13
Ming He, Linlin Jiang, Zhaozhou Ren, Guangbin Wang, Jiashi Wang
Osteosarcoma, the most common primary malignant bone tumor, usually arises in the metaphysis of long bones. Amplification and mutation of the epidermal growth factor receptor (EGFR) gene represent signature genetic abnormalities encountered in osteosarcoma. Noscapine is a benzylisoquinoline alkaloid derived from the opium poppy Papaver somniferum. Recently several studies have suggested its anti-cancer effect in melanoma, ovarian cancer, gliomas, breast cancer, lung cancer, and colon cancer. However, the underlying molecular mechanism for its anti-cancer effect still remains unclear...
November 10, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27809967/prevalence-of-toxoplasma-gondii-in-pet-dogs-in-mainland-china-a-meta-analysis
#14
Yu-Meng Gao, Huan Ding, Poppy H L Lamberton, Da-Bing Lu
Toxoplasmosis, caused by Toxoplasma gondii, is one of the most common zoonosis in the world, and can cause severe adverse consequences in pregnant women and immunosuppressed people. Throughout the world dogs are popular companion animals, however they are also important intermediate host of T. gondii and may play an instrumental role in mechanically transmitting Toxoplasma infection to humans. Therefore, an assessment of the level of T. gondii infection in pet dogs is of public health importance. To estimate the overall serological prevalence of toxoplasmosis in pet dogs in mainland China, we performed a meta-analysis using five bibliographic databases: CNKI, WanFang, VIP Chinese Journal Databases, PubMed and Google Scholar...
October 15, 2016: Veterinary Parasitology
https://www.readbyqxmd.com/read/27808606/compassion-in-action
#15
Poppy Butler
A 94-year-old patient came into clinic by himself for a routine appointment. It was immediately apparent that he was struggling with his personal hygiene - he had a strong odour and his clothes were soiled.
October 19, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27808289/importance-of-the-structural-integrity-of-a-carbon-conjugated-mediator-for-photocatalytic-hydrogen-generation-from-water-over-a-cds-carbon-nanotube-mos2-composite
#16
Molly Meng-Jung Li, Poppy Mills, Simon M Fairclough, Alex Robertson, Yung-Kang Peng, Jamie Warner, Chunyang Nie, Emmanuel Flahaut, Shik Chi Edman Tsang
Incorporation of CdS quantum dots is shown to significantly promote photocatalytic hydrogen production from water over single-layer MoS2 in a remote manner via their dispersions on a carbon nanotube as a nanocomposite: the hydrogen evolution rate is found to be critically dependent on the content and structural integrity of the carbon nanotube such that the double-walled carbon nanotube shows superior H2 production to a single-walled carbon nanotube because the inner carbon tubules survive from the structural damage during functionalization...
November 3, 2016: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/27803501/medication-therapy-management-for-patients-receiving-oral-chemotherapy-agents-at-a-community-oncology-center-a-pilot-study
#17
Nathan S Bertsch, Ross J Bindler, Poppy L Wilson, Anne P Kim, Beverly Ward
Purpose: To determine the impact of a pharmacist-driven medication therapy management (MTM) program for patients receiving oral chemotherapy agents. Methods: We assessed the impact of MTM consultations with a pharmacist for patients who were receiving a new prescription for an oral chemotherapy agent. Data were assessed for outcomes including (1) number of medication errors identified in electronic medical records (EMRs), (2) number of interventions performed by the pharmacist, (3) time spent on the MTM process, and (4) patient satisfaction...
October 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/27798031/the-environmental-footprint-of-morphine-a-life-cycle-assessment-from-opium-poppy-farming-to-the-packaged-drug
#18
Scott McAlister, Yanjun Ou, Elise Neff, Karen Hapgood, David Story, Philip Mealey, Forbes McGain
OBJECTIVE: To examine the environmental life cycle from poppy farming through to production of 100 mg in 100 mL of intravenous morphine (standard infusion bag). DESIGN: 'Cradle-to-grave' process-based life cycle assessment (observational). SETTINGS: Australian opium poppy farms, and facilities for pelletising, manufacturing morphine, and sterilising and packaging bags of morphine. MAIN OUTCOME MEASURES: The environmental effects (eg, CO2 equivalent ('CO2 e') emissions and water use) of producing 100 mg of morphine...
October 21, 2016: BMJ Open
https://www.readbyqxmd.com/read/27796999/using-solid-13-c-nmr-coupled-with-solution-31-p-nmr-spectroscopy-to-investigate-molecular-species-and-lability-of-organic-carbon-and-phosphorus-from-aquatic-plants-in-tai-lake-china
#19
Shasha Liu, Yuanrong Zhu, Fengchang Wu, Wei Meng, Hao Wang, Zhongqi He, Wenjing Guo, Fanhao Song, John P Giesy
Forms and labilities of plant-derived organic matters (OMs) including carbon (C) and phosphorus (P) were fundamental for understanding their release, degradation and environmental behaviour in lake ecosystems. Thus, solid (13)C and solution (31)P nuclear magnetic resonance (NMR) spectroscopy were used to characterize biomass of six aquatic plants in Tai Lake, China. The results showed that carbohydrates (61.2% of the total C) were predominant C functional group in the solid (13)C NMR spectra of plant biomass, which may indicate high lability and bioavailability of aquatic plants-derived organic matter in lakes...
October 31, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27793128/defining-cognitive-impairment-in-people-living-with-hiv-the-poppy-study
#20
Davide De Francesco, Jonathan Underwood, Frank A Post, Jaime H Vera, Ian Williams, Marta Boffito, Memory Sachikonye, Jane Anderson, Patrick W G Mallon, Alan Winston, Caroline A Sabin
BACKGROUND: The reported prevalence of cognitive impairment (CI) varies widely in cohorts of people living with HIV (PLWH); this may partly be due to the use of different diagnostic criteria. Agreement between diagnostic criteria of CI, the optimal definition to use, and associations with patient-reported cognitive symptoms have not been fully investigated. METHODS: Two hundred ninety PLWH aged >50 years and 97 matched negative controls completed a detailed assessment of cognitive function and three questions regarding cognitive symptoms...
October 28, 2016: BMC Infectious Diseases
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