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Gastritis, egd

Osamu Toyoshima, Yutaka Yamaji, Shuntaro Yoshida, Shuhei Matsumoto, Hiroharu Yamashita, Takamitsu Kanazawa, Keisuke Hata
BACKGROUND: Risk factors for gastric cancer during continuous infection with Helicobacter pylori have been well documented; however, little has been reported on the risk factors for primary gastric cancer after H. pylori eradication. We conducted a retrospective, endoscopy-based, long-term, large-cohort study to clarify the risk factors for gastric cancer following H. pylori eradication. METHODS: Patients who achieved successful H. pylori eradication and periodically underwent esophagogastroduodenoscopy surveillance thereafter at Toyoshima Endoscopy Clinic were enrolled...
September 7, 2016: Surgical Endoscopy
Taweesak Tongtawee, Theeraya Bartpho, Soraya Kaewpitoon, Natthawut Kaewpitoon, Chavaboon Dechsukhum, Wilairat Leeanansaksiri, Ryan A Loyd, Likit Matrakool, Sukij Panpimanmas
BACKGROUND: Helicobacter pylori is now recognized as a causative factor of chronic gastritis, gastroduodenal ulcers, gastric cancer and mucosaassociated lymphatic tissue lymphoma. Tolllike receptors are important bacterial receptors in gastric epithelial cell signaling transduction and play critical roles in gastric carcinogenesis. MATERIALS AND METHODS: A total of 400 patients undergoing esophagogastroduodenoscopy for investigation of chronic abdominal pain were genotyped for singlenucleotide polymorphisms (SNPs) in TLR1 (rs4833095) using TagMan SNPs genotyping assay by realtime PCR hybridization...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
Seong Ji Choi, Hyo Jung Kim, Jae Seon Kim, Young-Tae Bak, Jun Suk Kim
BACKGROUND: Radiation recall gastritis is rare but can be induced after concurrent chemoradiation for pancreatic cancer. We report a patient with pancreatic cancer who developed radiation-recall gastritis related to a combination of gemcitabine and erlotinib. CASE PRESENTATION: A 54-year-old female with unresectable pancreatic cancer received gemcitabine in combination with radiation therapy followed by chemotherapy with gemcitabine and erlotinib. After completing 2 cycles of chemotherapy, the patient had epigastric pain, nausea, and vomiting...
2016: BMC Cancer
Changqing Ma, Chien-Huan Chen, Ta-Chiang Liu
One of the main tasks for pathologists when evaluating gastric biopsies from patients with portal hypertensive gastropathy (PHG) is to examine whether there is increased mucosal vasculature as suggested by endoscopy. However, the full spectrum of pathology findings in patients with portal hypertension (pHTN) is largely unknown. We systematically characterized the endoscopic and pathologic features in gastric biopsies from pHTN patients (study group) and compared with those from patients without pHTN (control group)...
August 2016: Pathology, Research and Practice
Edith Lahner, Gianluca Esposito, Angelo Zullo, Cesare Hassan, Marilia Carabotti, Gloria Galli, Bruno Annibale
OBJECTIVE: In dyspeptic patients, esophagogastroduodenoscopy is often negative for visible lesions. Biopsies of the normal-appearing mucosa for Helicobacter pylori detection are not routinely obtained. Diagnostic gain of routine biopsies is still debated. This study aimed to assess the occurrence of H. pylori infection and related gastric premalignant conditions in dyspeptic patients without visible lesions at esophagogastroduodenoscopy and whether the presence/absence of endoscopically visible lesions may address the endoscopist to obtain gastric biopsies...
November 2016: Scandinavian Journal of Gastroenterology
Andrew Watson, Vadim Bul, Jonas Staudacher, Robert Carroll, Cemal Yazici
BACKGROUND AND AIMS: Emphysematous gastritis (EG) is caused by invasion of the gastric wall by gas-producing organisms and carries mortality rate up to 60%. Our investigation aimed to determine the predictors of survival and the secular trends in survival rates of subjects with EG. METHODS: PubMed search was completed to identify previous cases of EG. In addition, we included a recent case from our center. Statistical analysis was completed with two-sided Chi(2) tests for categorical data and t-tests for continuous variables using SPSS v...
June 20, 2016: Clinics and Research in Hepatology and Gastroenterology
Sean Bennett, Mišo Gostimir, Risa Shorr, Ranjeeta Mallick, Joseph Mamazza, Amy Neville
BACKGROUND: The necessity of routine preoperative esophagogastroduodenoscopy (EGD) before bariatric surgery is controversial. European guidelines recommend routine EGD while North American guidelines recommend a selective approach. OBJECTIVE: Perform a systematic review and meta-analysis to determine the proportion and scope of clinical findings discovered at preoperative EGD. SETTING: Academic hospital, Canada. METHODS: A search of MEDLINE, Embase, and Cochrane databases included MeSH terms "bariatric surgery," "endoscopy," and "preoperative...
June 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
Satoshi Kotani, Youichi Miyaoka, Aya Fujiwara, Kousuke Tsukano, Sayaka Ogawa, Satoshi Yamanouchi, Ryusaku Kusunoki, Hirofumi Fujishiro, Naruaki Kohge, Hideyuki Ohnuma, Yoshikazu Kinoshita
A 67-year-old woman was admitted to our hospital for further examination and for treatment of gastric neoplasia located on the posterior wall of the antrum of the stomach, as revealed by screening esophagogastroduodenoscopy. The patient had no history of Helicobacter pylori (H. pylori) eradication. Her serum H. pylori antibody and urea breath test results were negative, histopathological findings revealed no H. pylori bacteria, and endoscopic findings revealed no chronic gastritis. We performed endoscopic submucosal dissection (ESD)...
August 2016: Clinical Journal of Gastroenterology
Tomoe Kawamura, Atsushi Hiraoka, Akiko Toshimori, Hidetaro Ueki, Miho Kaneto, Toshihiko Aibiki, Tomonari Okudaira, Hiroka Yamago, Hiromasa Nakahara, Hideomi Tomida, Yoshifumi Suga, Nobuaki Azemoto, Kenichiro Mori, Hideki Miyata, Tomoyuki Ninomiya, Masashi Hirooka, Masanori Abe, Bunzo Matsuura, Yoichi Hiasa, Katsumi Kito, Kojiro Michitaka
A 63-year-old Japanese man whose white blood cell count and total-bilirubin and aminotransferase levels were elevated was referred to our hospital. Computed tomography did not reveal any abnormalities, and there was no evidence of gastritis or colitis on esophagogastroduodenoscopy. Although the patient had no history of drug use or allergies, a high concentration of eosinophils (80%) was noted. A liver biopsy revealed hepatitis with eosinophilic infiltration. The patient's alanine aminotransferase and eosinophil levels improved with the administration of steroids...
2016: Internal Medicine
Manish Parikh, Jennifer Liu, Dorice Vieira, Demetrios Tzimas, Daniel Horwitz, Andrew Antony, John K Saunders, Akuezunkpa Ude-Welcome, Adam Goodman
BACKGROUND: There is debate regarding preoperative endoscopy (EGD) in patients undergoing bariatric surgery. Some centers perform EGD routinely in all patients; others perform EGD selectively. The objective of this study was to perform a systematic review and meta-analysis of the existing literature to estimate how frequently preoperative EGD changes management. METHODS: Our review yielded 28 studies encompassing 6616 patients. Baseline characteristics including age and body mass index (BMI) were included...
May 20, 2016: Obesity Surgery
Ying Qing, Min Wang, Ying-Min Lin, Dong Wu, Jing-Yu Zhu, Lang Gao, Yan-Yan Liu, Teng-Fei Yin
AIM: To explore the correlation between Helicobacter pylori (H. pylori)-associated gastric diseases and colorectal neoplasia. METHODS: Patients included in this study underwent a colonoscopy and esophago-gastro-duodenoscopy (EGD) along with histopathological measurement between March 2012 and March 2015 at Qi-Lu Hospital of Shandong University, who also had results of H. pylori detection. A total of 233 cases were selected. Demographic data, H. pylori infection status (including results of rapid urease tests and gastric mucosa pathological examinations) and histopathological examination results of gastric and colorectal mucosa were gathered and analyzed...
May 14, 2016: World Journal of Gastroenterology: WJG
O Yu Joffe, I M Molnar, T V Tarasyuk, Yu P Tsyura, O P Stetsenko, M S Kryvopustov
Morphological changes in gastric mucosa were studied, optimal terms of bariatric operations performance after intragastric balloon (IGB) insertion were determined. Before the IGB insertion in 10 (35.7%) patients, in accordance to histological investigations, the changes in gastric mucosa were not revealed, and in 18 (64.3%) - chronic gastritis was established. In accordance to endoscopic investigation results, immediately after the IGB removal in 23 (82.1%) patients a pronounced erythematous gastropathy was noted, and in 5 (17...
October 2015: Klinichna Khirurhiia
Antonella Cianferoni
Triticum aestivum (bread wheat) is the most widely grown crop worldwide. In genetically predisposed individuals, wheat can cause specific immune responses. A food allergy to wheat is characterized by T helper type 2 activation which can result in immunoglobulin E (IgE) and non-IgE mediated reactions. IgE mediated reactions are immediate, are characterized by the presence of wheat-specific IgE antibodies, and can be life-threatening. Non-IgE mediated reactions are characterized by chronic eosinophilic and lymphocytic infiltration of the gastrointestinal tract...
2016: Journal of Asthma and Allergy
Jeffrey P Fiorenza, Alex M Tinianow, Walter W Chan
BACKGROUND AND AIMS: Dyspepsia is frequently encountered by primary care providers (PCP) and gastroenterologists (GI). While esophagogastroduodenoscopy (EGD) may be useful, current guidelines suggest a proton pump inhibitor (PPI) trial and H. pylori (HP) test-and-treat before EGD for low-risk patients. This study aimed to evaluate pre-EGD management and endoscopic outcomes in this population. METHODS: This was a retrospective cohort study of low-risk dyspepsia patients (age ≤55, no alarm features) undergoing EGD at an ambulatory endoscopy center from January 2011 to March 2012...
October 2016: Digestive Diseases and Sciences
Taweesak Tongtawee, Soraya Kaewpitoon, Natthawut Kaewpitoon, Chavaboon Dechsukhum, Wilairat Leeanansaksiri, Ryan A Loyd, Likit Matrakool, Sukij Panpimanmas
BACKGROUND: Colorectal polyps are common in Thailand, particularly in the northeastern region. The present study aimed to determine any correlation between Helicobacter pylori-associated gastritis and colorectal polyps in the Thai population. MATERIALS AND METHODS: A total of 303 patients undergoing esophagogastroduodenoscopy with colonoscopy for investigation of chronic abdominal pain participated in this study from November 2014 to October 2015. A diagnosis of Helicobacter pylori associated gastritis was made if the bacteria were seen on histopathological examination and a rapid urease test was positive...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
Do Hyun Kim, Ho Dong Kim, Hyeuk Park, Seung Choi, Jae Won Beom, Woo Jong Kim, Chang Kook Park, Young Jik Lee, Ju Young Park, Hyung Rag Kim, Chul Park, Young Eun Joo, Young Do Jung
BACKGROUND/AIMS: To evaluate a new monoclonal antibody for Helicobacter pylori urease in gastric tissue. METHODS: A total of 107 volunteers were enrolled. All subjects underwent a (13)C-urea breath test and esophagogastroduodenoscopy. Gastric aspirates were analyzed for pH and ammonia. Six biopsy specimens in the gastric antrum and body were obtained for a rapid urease test and histology. The new monoclonal antibody-based H. pylori urease test (HPU) was performed to rapidly and qualitatively detect urease in two biopsy specimens...
January 2016: Korean Journal of Internal Medicine
Kunihiro Kato, Kazunari Tominaga, Satoshi Sugimori, Yasuaki Nagami, Noriko Kamata, Hirokazu Yamagami, Tetsuya Tanigawa, Masatsugu Shiba, Toshio Watanabe, Yasuhiro Fujiwara, Tetsuo Arakawa
A 64-year-old man presented with epigastralgia and nausea after an acute exacerbation of chronic pancreatitis. Abdominal computed tomography revealed remarkable thickening of the gastric wall and intramural hypodense areas. Esophagogastroduodenoscopy showed a large gastric ulcer surrounded by an edematous mucosa and mucopus. The results of a culture from a biopsy of the lesion indicated phlegmonous gastritis. The patient was successfully treated with an antibiotic without gastrectomy.
2015: Internal Medicine
Mosaburo Kainuma, Norihiro Furusyo, Yoshihisa Urita, Masaharu Nagata, Takeshi Ihara, Takeshi Oji, Toshiya Nakaguchi, Takao Namiki, Jun Hayashi
BACKGROUND: The relation between tongue color and gastroesophageal disease is unclear. This study was done to investigate the associations between tongue color (TC), endoscopic findings, Helicobacter.pylori infection status, and serological atrophic gastritis (SAG). METHODS: The participants were 896 residents of Ishigaki Island, Okinawa, aged 28-86 years. The tongue was photographed, esophagogastroduodenoscopy was done, and serum antibody to H.pylori was measured...
2015: BMC Complementary and Alternative Medicine
Yi Yu, Baoxiang Wang, Lan Yuan, Hui Yang, Xinqiong Wang, Yuan Xiao, Hong Mei, Chundi Xu
Objective This study aims to analyze the clinical and endoscopic presentations of upper gastrointestinal bleeding (UGIB) in the Chinese children. Methods A 10-year retrospective study was made on children with UGIB and undertaken esophagogastroduodenoscopy (EGD) from 4 tertiary referral centers in China. Results Of the 1218 children studied, the bleeding source was found in 76.4%. Erosive gastritis was the most common endoscopic finding (33.5%), followed by duodenal ulcer (23.2%). The proportion of erosive gastritis decreased with age (correlation coefficient = -0...
August 2016: Clinical Pediatrics
Hyunsoo Chung, Young Eun Chon, Seung Up Kim, Sang Kil Lee, Kyu Sik Jung, Kwang-Hyub Han, Chae Yoon Chon
BACKGROUND: Erosive esophagitis and fatty liver share obesity and visceral fat as common critical pathogenesis. However, the relationship between the amount of hepatic fat and the severity of erosive esophagitis was not well investigated, and there is no risk estimation model for erosive esophagitis. AIM: To evaluate the relationship between the amount of hepatic fat and the severity of erosive esophagitis and then develop a risk estimation model for erosive esophagitis...
February 2016: Digestive Diseases and Sciences
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