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upper gastrointestinal bleeding variceal

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https://www.readbyqxmd.com/read/29851765/-acute-variceal-bleeding-causes-significant-morbidity
#1
Marta Carneiro de Moura, Shiyi Chen, Binita M Kamath, Vicky Lee Ng, Simon C Ling
BACKGROUND AND AIMS: The need for primary prophylaxis of variceal bleeding in children is unclear due to insufficient evidence of the efficacy of prophylactic therapy and the mortality and morbidity associated with the first bleeding event. Previous studies have provided estimates of mortality. We aimed to investigate the morbidity associated with acute variceal bleeding (AVB) in children and to identify contributing factors. METHODS: We retrospectively reviewed children with chronic liver disease or portal vein thrombosis admitted with acute upper gastrointestinal bleeding between 2000 and 2015...
May 30, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29791429/-clinical-practice-guideline-for-the-evaluation-and-management-of-upper-gastrointestinal-bleeding-for-the-peruvian-social-security-essalud
#2
Jorge Vásquez-Quiroga, Alvaro Taype-Rondan, Jessica Hanae Zafra-Tanaka, Ericson Arcana-López, Luis Cervera-Caballero, Javier Contreras-Turin, Katherine Guzmán-Cáceres, Juan Llatas-Perez, Luis Marin-Calderón, Alejandro Piscoya, Daniel Vargas-Blácido, Nelly Vásquez-Valverde, Raúl Timaná-Ruiz
OBJECTIVE: To provide evidence-based clinical recommendations for the evaluation and management of patients with upper gastrointestinal bleeding (UGB) in the Peruvian Social Security (EsSalud). MATERIALS AND METHODS: A local guideline development group (local GDG) was established, including specialists in gastroenterology and methodologists. The local GDG formulated 11 clinical questions to be answered by this clinical practice guide (CPG). We searched and selected CPG of UGB published from 2012, which answered the posed questions and obtained a score higher than 60% in domains 1 and 3 of the Appraisal of Guidelines for Research and Evaluation II (AGREE-II) tool...
January 2018: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/29774150/the-effect-of-off-hours-hospital-admission-on-mortality-and-clinical-outcomes-for-patients-with-upper-gastrointestinal-hemorrhage-a-systematic-review-and-meta-analysis-of-20-cohorts
#3
Xian Feng Xia, Philip Wai Yan Chiu, Kelvin Kam Fai Tsoi, Francis Ka Leung Chan, Joseph Jao Yiu Sung, James Yun Wong Lau
Objective: The objective of this article is to evaluate the relationship between off-hours hospital admission (weekends, public holidays or nighttime) and mortality for upper gastrointestinal hemorrhage (UGIH). Methods: Medline, Embase, Scopus, and the Chinese Biomedical Literature were searched through December 2016 to identify eligible records for inclusion in this meta-analysis. A random-effects model was applied. Results: Twenty cohort studies were included for analysis...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29748820/trans-arterial-embolization-of-non-variceal-upper-gastrointestinal-bleeding-is-the-use-of-ethylene-vinyl-alcohol-copolymer-as-safe-as-coils
#4
Marcello Andrea Tipaldi, Gianluigi Orgera, Miltiadis Krokidis, Alberto Rebonato, Daniele Maiettini, Simone Vagnarelli, Cesare Ambrogi, Michele Rossi
PURPOSE: The safety of liquid embolics over the conventional coils for the treatment of non-variceal upper gastrointestinal bleeding (UGIB) approach is still unclear. Purpose of this study is to assess the safety of ethylene-vinyl alcohol copolymer (EVOH 6%) over coils in the treatment of UGIB. MATERIALS AND METHODS: All the upper gastrointestinal tract embolization procedures performed in a single center in a 6-year period were reviewed. Patients embolised with coils (Group A) versus those embolised with EVOH 6% (Group B) were compared...
May 10, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29742774/massive-upper-gastrointestinal-bleeding-post-whipple-s-surgery-from-anastomotic-varices-due-to-mesenteric-hypertension
#5
Yu Jun Wong, Farah Gillian Irani, Malcolm Tan, Melissa Teo
No abstract text is available yet for this article.
May 9, 2018: Endoscopy
https://www.readbyqxmd.com/read/29719748/does-early-endoscopy-improve-mortality-in-patients-with-acute-non-variceal-gastrointestinal-bleeding-a-retrospective-review
#6
Umair Iqbal, Hafsa Anwar, Hunaiz Patel, Ahmad Chaudhary, Pascale Raymond
Introduction Initial management of acute upper gastrointestinal bleeding (UGIB) aims towards aggressive fluid resuscitation to maintain hemodynamic stability. Existing evidence regarding the benefit of early endoscopy is unclear with some studies suggesting mortality benefits and some suggesting otherwise. The purpose of this study is to evaluate if there is any mortality benefit of doing early endoscopy within 24 hours of presentation. Methods From July 2013 to July 2016, 179 patients admitted with a diagnosis of non-variceal UGIB were retrospectively reviewed...
February 28, 2018: Curēus
https://www.readbyqxmd.com/read/29713571/superior-vena-cava-obstruction-a-rare-cause-of-recurrent-esophageal-variceal-bleeding
#7
Agazi Gebreselassie, Ahmad Awan, Hamid Yaqoob, Adeyinka Laiyemo
"Downhill" esophageal varices are formed in upper two-thirds of the esophagus as a consequence of a superior vena cava obstruction. We present a case of 55-year-old African-American female with a medical history of multiple comorbidities, including end-stage renal disease, who presented with an upper gastrointestinal bleed and was found to have distended neck veins on physical examination. She gave a history of the insertion of an intravenous central line in her neck area for hemodialysis purposes about six years previously...
February 26, 2018: Curēus
https://www.readbyqxmd.com/read/29691276/asia-pacific-working-group-consensus-on-non-variceal-upper-gastrointestinal-bleeding-an-update-2018
#8
Joseph Jy Sung, Philip Cy Chiu, Francis K L Chan, James Yw Lau, Khean-Lee Goh, Lawrence Hy Ho, Hwoon-Young Jung, Jose D Sollano, Takuji Gotoda, Nageshwar Reddy, Rajvinder Singh, Kentaro Sugano, Kai-Chun Wu, Chun-Yin Wu, David J Bjorkman, Dennis M Jensen, Ernst J Kuipers, Angel Lanas
Non-variceal upper gastrointestinal bleeding remains an important emergency condition, leading to significant morbidity and mortality. As endoscopic therapy is the 'gold standard' of management, treatment of these patients can be considered in three stages: pre-endoscopic treatment, endoscopic haemostasis and post-endoscopic management. Since publication of the Asia-Pacific consensus on non-variceal upper gastrointestinal bleeding (NVUGIB) 7 years ago, there have been significant advancements in the clinical management of patients in all three stages...
April 24, 2018: Gut
https://www.readbyqxmd.com/read/29671413/non-variceal-upper-gastrointestinal-bleeding
#9
REVIEW
Angel Lanas, Jean-Marc Dumonceau, Richard H Hunt, Mitsuhiro Fujishiro, James M Scheiman, Ian M Gralnek, Helen E Campbell, Alaa Rostom, Càndid Villanueva, Joseph J Y Sung
Non-variceal upper gastrointestinal bleeding (NVUGIB) is bleeding that develops in the oesophagus, stomach or proximal duodenum. Peptic ulcers, caused by Helicobacter pylori infection or use of NSAIDs and low-dose aspirin (LDA), are the most common cause. Although the incidence and mortality associated with NVUGIB have been decreasing owing to considerable advances in the prevention and management of NVUGIB over the past 20 years, it remains a common clinical problem with an annual incidence of ∼67 per 100,000 individuals in the United States in 2012...
April 19, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29668596/predictors-of-in-hospital-mortality-in-a-cohort-of-elderly-egyptian-patients-with-acute-upper-gastrointestinal-bleeding
#10
Mohamed A Elsebaey, Heba Elashry, Tamer A Elbedewy, Ahmed A Elhadidy, Noha E Esheba, Sherif Ezat, Manal Saad Negm, Yousry Esam-Eldin Abo-Amer, Mohamed El Abgeegy, Heba Fadl Elsergany, Loai Mansour, Sherief Abd-Elsalam
Acute upper gastrointestinal bleeding (UGIB) affects large number of elderly with high rates of morbidity and mortality. Early identification and management of the factors predicting in-hospital mortality might decrease mortality. This study was conducted to identify the causes of acute UGIB and the predictors of in-hospital mortality in elderly Egyptian patients.286 elderly patients with acute UGIB were divided into: bleeding variceal group (161 patients) and bleeding nonvariceal group (125 patients). Patients' monitoring was done during hospitalization to identify the risk factors that might predict in-hospital mortality in elderly...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29644032/severe-acute-gallstone-pancreatitis-with-diffuse-hemorrhagic-gastritis
#11
Timothy J Harris, William C Beck, Avi Bhavaraju, Benjamin Davis, Mary K Kimbrough, Joseph C Jensen, Anna Privratsky, John R Taylor, Kevin W Sexton
A 67-year-old male presented with acute pancreatitis secondary to gallstones, also known as acute biliary pancreatitis, and subsequently developed gastric outlet obstruction and was transferred to our hospital. A gastro-jejunal feeding tube was placed and an open cholecystectomy was performed. The patient had a pancreatic drain placed for interval increase in pancreatic necrosis and then nearly exsanguinated from gastroduodenal artery pseudoaneurysm bleed. This was managed by coiling the gastroduodenal artery...
March 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29629057/etiology-of-gastrointestinal-bleeding-in-children-referred-to-pediatric-wards-of-mashhad-hospitals-iran
#12
Seyed Ali Jafari, Mohammad Ali Kiani, Hamid Reza Kianifar, Mohammad Mansooripour, Elahe Heidari, Maryam Khalesi
Background: Gastrointestinal (GI) bleeding, which has several clinical manifestation and origins, is known as one of the most life-threatening events in children. Several etiologies have been suggested for GI bleeding. Objective: To determine the most important causes of GI bleeding in children referred to Ghaem Hospital and Dr. Sheikh Hospital, Mashhad, Iran. Methods: In this cross-sectional study, after obtaining written informed consent of their parents, 113 patients aging from newborn infants to 18-year-old children with GI bleeding admitted to Ghaem Hospital and Dr...
February 2018: Electronic Physician
https://www.readbyqxmd.com/read/29626014/glasgow-blatchford-score-and-risk-stratifications-in-acute-upper-gastrointestinal-bleed-can-we-extend-this-to-2-for-urgent-outpatient-management
#13
Kelly Chatten, Huw Purssell, Ashwini Kumar Banerjee, Stephanie Soteriadou, Yeng Ang
Upper gastrointestinal (GI) bleeds are a common presentation to emergency departments in the UK. The Glasgow Blatchford score (GBS) predicts the outcome of patients at presentation. Current UK and European guidelines recommend outpatient management for a GBS of 0. In the current study, our aim was to assess whether extending the GBS allows for early discharge while maintaining patient safety. We also analysed whether pathologies could be missed by discharging patients too early. Data were retrospectively collected on patients admitted with symptoms of an upper GI bleed between 1 October 2013 and 10 June 2016...
March 2018: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/29610020/pharmacological-treatment-of-gastrointestinal-bleeding-due-to-angiodysplasias-a-position-paper-of-the-italian-society-of-gastroenterology-sige
#14
REVIEW
Gerardo Nardone, Debora Compare, Alberto Martino, Alba Rocco
Angioectasias (AD) belong to benign vascular malformations of the gastrointestinal tract and are responsible for about 4-7% of upper non variceal bleeding, 30-40% of small bowel occult bleeding and 3-40% of colonic bleeding episodes. Gastrointestinal haemorrhage secondary to AD represents an important diagnostic and therapeutic problem that negatively impacts on the quality of life of patients and heath care costs. Endoscopic interventions are the mainstay in both diagnosis and treatment of vascular malformations...
June 2018: Digestive and Liver Disease
https://www.readbyqxmd.com/read/29601829/thirty-day-readmission-among-patients-with-non-variceal-upper-gastrointestinal-hemorrhage-and-effects-on-outcomes
#15
Marwan S Abougergi, Heather Peluso, John R Saltzman
BACKGROUND & AIMS: We aimed to determine the rate of hospital readmission within 30 days of non-variceal upper gastrointestinal hemorrhage and its impact on mortality, morbidity, and health care use in the United States. METHODS: We performed a retrospective study using the Agency for Healthcare Research and Quality's Healthcare Cost and Utilization Project Nationwide Readmission Database for the year 2014 (data on 14.9 million hospital stays at 2048 hospitals in 22 states)...
March 28, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29601652/comparison-of-clinical-outcomes-between-variceal-and-non-variceal-gastrointestinal-bleeding-in-patients-with-cirrhosis
#16
Parul Tandon, Kirles Bishay, Stacey Fisher, Dominique Yelle, Ian Carrigan, Krista Wooller, Erin Kelly
BACKGROUND AND AIM: Acute upper gastrointestinal bleeding (UGIB) in cirrhosis is associated with significant morbidity and mortality and can be classified as acute variceal bleeding (AVB) or non-variceal bleeding (NVB). Differences in mortality, hospital length of stay (LOS), and 30-day readmission have yet to be determined. As such, the study aimed to evaluate differences in these clinical outcomes in cirrhotic patients admitted with UGIB. METHODS: This retrospective study included all cirrhotic patients hospitalized for UGIB who underwent upper endoscopy from July 2014 to July 2016...
March 30, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29575962/inhospital-and-delayed-mortality-after-upper-gastrointestinal-bleeding-an-analysis-of-risk-factors-in-a-prospective-series
#17
Rita Jiménez-Rosales, Francisco Valverde-López, Francisco Vadillo-Calles, Juan Gabriel Martínez-Cara, Mercedes López de Hierro, Eduardo Redondo-Cerezo
BACKGROUND: Detailed analyses of mortality after upper gastrointestinal (GI) bleeding are lacking. Follow-up rarely extends beyond 30 days. AIMS: Our aim was to analyze in-hospital and delayed 6-months mortality, identifying risk factors. METHODS: This was a prospective study on patients with upper GI bleeding over 36 months. Clinical outcomes were in-hospital and delayed-6 month-mortality. RESULTS: Four hundred and forty-none patients were included...
March 26, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29570557/the-use-and-safety-of-a-novel-haemostatic-spray-in-the-endoscopic-management-of-acute-non-variceal-upper-gastrointestinal-bleeding-in-children
#18
Mike Thomson, Arun Urs, Priya Narula, Prithviraj Rao, Dalia Belsha
AIMS AND BACKGROUND: Advanced endo-haemostatic technique performance and experience is extremely variable in distribution amongst pediatric endoscopists. Haemostatic spray (Hemospray®), a novel endo-haemostatic topically applied powder has the advantage of extreme ease of use and; hence may lower the threshold of competency required by the endoscopist thereby potentially reducing mortality. The aim of the study is to prospectively evaluate the efficacy and the safety of haemostatic spray in paediatric patients with AUGIB...
March 22, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29525375/evaluation-and-management-of-non-variceal-upper-gastrointestinal-bleeding
#19
REVIEW
Ronald Samuel, Mohammad Bilal, Obada Tayyem, Praveen Guturu
Non-variceal upper gastrointestinal bleeding continues to be an important cause of morbidity and mortality. The most common causes include peptic ulcer disease, Mallory-Weiss syndrome, erosive gastritis, duodenitis, esophagitis, malignancy, angiodysplasias and Dieulafoy's lesion. Initial assessment and early aggressive resuscitation significantly improves outcomes. Upper gastrointestinal endoscopy continues to be the gold standard for diagnosis and treatment. We present a comprehensive review of literature for the evaluation and management of non-variceal upper gastrointestinal bleeding...
July 2018: Disease-a-month: DM
https://www.readbyqxmd.com/read/29487770/point-of-care-ultrasound-diagnosis-of-upper-gastrointestinal-bleeding
#20
Robert P Jamplis, Lucas Friedman, Srikar Adhikari
A 28-year-old male was brought to the emergency department by the Emergency medical services (EMS) after being found unconscious and unresponsive. Upon arrival, he was hypotensive, intubated with a Glasgow Coma Scale (GCS) 3T, without the signs of trauma or the evidence of bleeding. A focused assessment with sonography in trauma (FAST), point-of-care ultrasound (POCUS) was performed, obscuring part of the spleen from the distended stomach, which was filled with the heterogeneous contents, with the internal movement being identified...
December 17, 2017: Curēus
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