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https://www.readbyqxmd.com/read/28109988/epilepsy-and-restless-legs-syndrome
#1
James D Geyer, Emery E Geyer, Zachary Fetterman, Paul R Carney
OBJECTIVE: Restless legs syndrome (RLS) is a common neurological movement disorder occurring in approximately 10% of the general population. The prevalence of moderately severe RLS is 2.7% overall (3.7% for women and 1.7% for men). Epilepsy is also a common neurological disorder with significant associated morbidity and impact on quality of life. We evaluated the severity and frequency of primary RLS in patients with localization-related temporal lobe epilepsy (TLE) and investigated the role of prodromal RLS symptoms as a warning sign and lateralizing indicator...
January 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28107900/quality-of-sleep-in-renal-transplant-recipients-and-patients-on-hemodialysis
#2
Paraskevi G Liaveri, Dimitris Dikeos, Ioannis Ilias, Eirini P Lygkoni, Ioannis N Boletis, Chryssanthi Skalioti, Thomas Paparrigopoulos
BACKGROUND: Sleep disorders are very common in patients with chronic kidney disease and they may not always subside after kidney transplantation. AIM AND METHODS: The aim of this cross-sectional study was to evaluate the self-reported quality of sleep, insomnia problems in particular, and examine the factors that disturb sleep of kidney transplant recipients (KTx: n=152) in comparison to age- and sex-matched patients on dialysis (HD: n=67) and participants with normal renal function (NOR: n=49), through the administration of the Athens Insomnia Scale (AIS) at least six months after transplantation...
February 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28101479/excessive-daytime-sleepiness-and-sleep-disorders-in-a-population-of-patients-with-epilepsy-a-case-control-study
#3
Matilde Gammino, Leila Zummo, Anna Lo Bue, Lidia Urso, Valeria Terruso, Oreste Marrone, Brigida Fierro, Ornella Daniele
BACKGROUND AND PURPOSE: There are several primary causes for excessive daytime sleepiness (EDS) and sleep disorders in patients with epilepsy. Up to now, studies in the literature report conflicting data in terms of both prevalence and aetiology. The aim of our study was therefore to evaluate the prevalence of EDS and some sleep disorders in a population of patients with epilepsy treated with no more than two antiepileptic drugs (AEDs). We also investigated the role of the depression of mood as a variable that can negatively affect EDS...
December 2016: Journal of Epilepsy Research
https://www.readbyqxmd.com/read/28101323/gabapentin-treatment-in-clozapine-induced-restless-legs-syndrome-two-cases-and-a-review-of-the-literature
#4
REVIEW
Vijaya Kumar, Ganesan Venkatasubramanian
Restless legs syndrome (RLS) is a neuro-sensorimotor disorder affecting 2-4% of adults. It is characterized by intense urges to move the legs, associated with unpleasant sensory disturbances in the legs occurring at rest and manifests mostly in the evening and night, relieved by movement. Diagnosis is primarily based on clinical presentation and the consensus criteria for the diagnosis have been established. Antipsychotics, the dopamine antagonists, have been reported to induce RLS. Dopamine agonists, the effective first-line treatment of RLS, carry the risk of inducing or worsening psychosis...
January 2017: Therapeutic Advances in Psychopharmacology
https://www.readbyqxmd.com/read/28095964/f-wave-duration-parameters-as-a-specific-and-sensitive-tool-for-diagnosis-of-restless-legs-syndrome
#5
Patrizia Congiu, Maria Livia Fantini, Giulia Milioli, Paolo Tacconi, Michela Figorilli, Gioia Gioi, Bruno Pereira, Francesco Marrosu, Liborio Parrino, Monica Puligheddu
STUDY OBJECTIVES: Restless legs syndrome, also known as Willis-Ekbom disease (RLS/WED), is a frequent condition, though its pathophysiology is not completely understood. The diagnosis of RLS/WED relies on clinical criteria, and the only instrumental tool, the suggested immobilization test, may lead to equivocal results. Recently, neurophysiological parameters related to F-wave duration have been proposed as a diagnostic aid. The aim of this study is to assess and compare the diagnostic values of these parameters in diagnosis of RLS/WED...
January 11, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28091872/impact-of-revascularization-of-coronary-chronic-total-occlusion-on-left-ventricular-function-and-electrical-stability-analysis-by-speckle-tracking-echocardiography-and-signal-averaged-electrocardiogram
#6
Yohei Sotomi, Atsunori Okamura, Katsuomi Iwakura, Motoo Date, Hiroyuki Nagai, Tomohiro Yamasaki, Yasushi Koyama, Koichi Inoue, Yasushi Sakata, Kenshi Fujii
The present study aimed to assess the mechanisms of effects of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) from two different aspects: left ventricular (LV) systolic function assessed by two-dimensional speckle tracking echocardiography (2D-STE) and electrical stability evaluated by late potential on signal-averaged electrocardiogram (SAECG). We conducted a prospective observational study with consecutive CTO-PCI patients. 2D-STE and SAECG were performed before PCI, and after 1-day and 3-months of procedure...
January 13, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28065687/restless-legs-syndrome-and-cardiovascular-disease-a-research-roadmap
#7
REVIEW
Daniel J Gottlieb, Virend K Somers, Naresh M Punjabi, John W Winkelman
In this paper, we first critically appraise the epidemiologic literature examining the association of restless legs syndrome (RLS) with cardiovascular disease (CVD) and then consider whether lessons learned from the study of cardiovascular consequences of other sleep disorders might inform a research agenda to examine the potential mechanisms of cardiovascular morbidity of RLS. Cross-sectional and longitudinal studies are both mixed as to whether there is a meaningful association of RLS and CVD. On the other hand, numerous cross-sectional and longitudinal observational studies have shown a strong association of obstructive sleep apnea (OSA) with CVD risk...
October 27, 2016: Sleep Medicine
https://www.readbyqxmd.com/read/28065402/genetics-of-restless-legs-syndrome
#8
Juliane Winkelmann, Barbara Schormair, Lan Xiong, Patrick A Dion, David B Rye, Guy A Rouleau
At the outset of genetic studies in restless legs syndrome (RLS), the disorder was assumed to be a classical monogenic disorder that runs in families. However, years of family studies did not reveal any causally-related genes or genetic variants. The advent of high-throughput genotyping technology led to a change; genome-wide association studies in large case-control samples became feasible, which led to the identification of first genetic risk variants for RLS. Variants detected by this approach are common ones, which that individually confer only a minor increase in risk of disease...
November 12, 2016: Sleep Medicine
https://www.readbyqxmd.com/read/28063107/the-relationship-between-right-to-left-shunt-and-brain-white-matter-lesions-in-japanese-patients-with-migraine-a-single-center-study
#9
Akio Iwasaki, Keisuke Suzuki, Hidehiro Takekawa, Ryotaro Takashima, Ayano Suzuki, Shiho Suzuki, Koichi Hirata
BACKGROUND: There may be a link between right-to-left shunt (RLs) and brain white matter lesions (WMLs) in patients with migraine. In this study, we assessed the relationship between WMLs and RLs in Japanese migraine patients. METHODS: A total of 107 consecutive patients with migraine with (MA) and without aura (MWOA) were included in this study. Contrast transcranial Doppler ultrasound was used to detect RLs. WMLs were graded using brain magnetic resonance imaging based on well-established criteria...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28057495/iron-and-restless-legs-syndrome-treatment-genetics-and-pathophysiology
#10
James R Connor, Stephanie M Patton, Konrad Oexle, Richard Allen
In this article, we review the original findings from MRI and autopsy studies that demonstrated brain iron status is insufficient in individuals with restless legs syndrome (RLS). The concept of deficient brain iron status is supported by proteomic studies from cerebrospinal fluid (CSF) and from the clinical findings where intervention with iron, either dietary or intravenous, can improve RLS symptoms. Therefore, we include a section on peripheral iron status and how peripheral status may influence both the RLS symptoms and treatment strategy...
November 10, 2016: Sleep Medicine
https://www.readbyqxmd.com/read/28055939/efficient-approach-for-rls-type-learning-in-tsk-neural-fuzzy-systems
#11
Jen-Wei Yeh, Shun-Feng Su
This paper presents an efficient approach for the use of recursive least square (RLS) learning algorithm in Takagi-Sugeno-Kang neural fuzzy systems. In the use of RLS, reduced covariance matrix, of which the off-diagonal blocks defining the correlation between rules are set to zeros, may be employed to reduce computational burden. However, as reported in the literature, the performance of such an approach is slightly worse than that of using the full covariance matrix. In this paper, we proposed a so-called enhanced local learning concept in which a threshold is considered to stop learning for those less fired rules...
December 29, 2016: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28052812/newcastle-disease-virus-vectored-infectious-laryngotracheitis-vaccines-protect-commercial-broiler-chickens-in-the-presence-of-maternally-derived-antibodies
#12
Qingzhong Yu, Stephen Spatz, Yufeng Li, Jilong Yang, Wei Zhao, Zhenyu Zhang, Guoyuan Wen, Maricarmen Garcia, Laszlo Zsak
Newcastle disease virus (NDV) recombinants expressing the infectious laryngotracheitis virus (ILTV) glycoproteins B and D have previously been demonstrated to confer complete clinical protection against virulent ILTV and NDV challenges in naive chickens. We extended this study to assess whether maternally derived antibody (MDA) against NDV and ILTV would interfere with protection in vaccinated broiler chickens. Chickens with a mean NDV MDA hemagglutination inhibition (HI) titer of 6.4 (log2) and detectable ILTV neutralization (VN) antibodies at hatch were vaccinated with rLS/ILTV-gB or rLS/ILTV-gD at 1 or 10day of age (DOA) or on both days...
February 1, 2017: Vaccine
https://www.readbyqxmd.com/read/28035549/prevalence-of-restless-legs-syndrome-in-patients-with-inflammatory-bowel-disease
#13
Ikuko Takahara, Fuminao Takeshima, Tatsuki Ichikawa, Toshihisa Matsuzaki, Hidetaka Shibata, Satoshi Miuma, Yuko Akazawa, Hisamitsu Miyaaki, Naota Taura, Kazuhiko Nakao
BACKGROUND AND AIM: There has been increased interest in sleep disorders in patients with inflammatory bowel disease (IBD). Studies in North America and Europe reported that the prevalence of restless legs syndrome (RLS) is much higher in patients with Crohn's disease (CD) than in the general population. The aim of this study was to reveal the prevalence and clinical features of RLS in Japanese patients with IBD and investigate the influence of RLS on sleep quality and quality of life (QOL)...
December 29, 2016: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28029145/real-time-multi-target-localization-from-unmanned-aerial-vehicles
#14
Xuan Wang, Jinghong Liu, Qianfei Zhou
In order to improve the reconnaissance efficiency of unmanned aerial vehicle (UAV) electro-optical stabilized imaging systems, a real-time multi-target localization scheme based on an UAV electro-optical stabilized imaging system is proposed. First, a target location model is studied. Then, the geodetic coordinates of multi-targets are calculated using the homogeneous coordinate transformation. On the basis of this, two methods which can improve the accuracy of the multi-target localization are proposed: (1) the real-time zoom lens distortion correction method; (2) a recursive least squares (RLS) filtering method based on UAV dead reckoning...
December 25, 2016: Sensors
https://www.readbyqxmd.com/read/28027615/living-donor-liver-transplantation-using-an-extended-right-lateral-sector-graft
#15
N Yoshida, T Takamoto, T Hashimoto, Y Maruyama, H Abe, K Shimada, T Takayama, M Makuuchi
There are three grafts (left, right and right lateral sector [RLS]) available for adult living donor liver transplantation (LDLT), and we herein report LDLT performed using an extended RLS graft. An extended RLS graft is an RLS plus right paramedian dorsal sector (RPMS-dorsal) graft. In this case, the proportion of the RLS graft of the predicted graft volume (GV) to the recipient's standard liver volume (SLV) was only 17.7%, preoperatively. A three-dimensional (3D) analysis, showed that the RPMS-dorsal branches of the portal veins branched from the posterior trunk not the anterior trunk...
December 27, 2016: Liver Transplantation
https://www.readbyqxmd.com/read/28018825/late-clinical-presentation-of-inferior-vena-cava-deviation-into-the-left-atrium-following-atrial-septal-defect-repair-in-the-childhood
#16
Ali El-Sayed Ahmad, Peter Kleine, Thomas Lehnert, Anton Moritz
A 19-year-old woman underwent ASD closure with patch in the childhood. Fifteen years later, she presented with severe cyanosis and dyspnea on exertion. Clinical diagnostics revealed a dislocation of the patch resulting in a right-to-left shunt (RLS) that was compensated in the past years by a recurrent ASD allowing a left-to-right shunt (LRS). The existing balance between interatrial shunts vanished by the growth of the patient leading to the clinical deterioration. After successful redo surgery, the patient was discharged home 8 days postoperatively...
December 2016: Thoracic and Cardiovascular Surgeon Reports
https://www.readbyqxmd.com/read/28017182/prevalence-of-restless-legs-syndrome-during-detoxification-from-alcohol-and-opioids
#17
Susan E Mackie, R Kathryn McHugh, Katherine McDermott, Margaret L Griffin, John W Winkelman, Roger D Weiss
BACKGROUND AND AIMS: Restless legs syndrome (RLS) is a movement disorder associated with adverse health outcomes and decreased quality of life. Small case series suggest that symptoms of RLS occur during opioid withdrawal. However, the prevalence is unknown. METHODS: We conducted an observational study to determine the prevalence of RLS among inpatients patients receiving buprenorphine detoxification from opioids. To assess the specificity of RLS to opioid detoxification, we also evaluated patients receiving detoxification from alcohol as a comparison group...
February 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/27994356/a-double-blind-randomized-controlled-trial-to-compare-the-efficacy-and-tolerability-of-fixed-doses-of-ropinirole-bupropion-and-iron-in-treatment-of-restless-legs-syndrome-willis-ekbom-disease
#18
Kirti Vishwakarma, Juhi Kalra, Ravi Gupta, Mukesh Sharma, Taruna Sharma
BACKGROUND: We aimed to compare the efficacy of fixed doses of bupropion and ropinirole and iron alone for the treatment of restless legs syndrome (RLS) and to look for the tolerability of these medications. MATERIALS AND METHODS: Patients diagnosed with RLS were randomly divided into three groups with thirty patients in each group (Group A: Bupropion [300 mg/day], Group B: Ropinirole [0.25-0.5 mg/day], and Group C: Oral iron [150 mg elemental iron] along with folic acid [500 μg])...
October 2016: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/27992445/window-based-channel-impulse-response-prediction-for-time-varying-ultra-wideband-channels
#19
A M Al-Samman, M H Azmi, T A Rahman, I Khan, M N Hindia, A Fattouh
This work proposes channel impulse response (CIR) prediction for time-varying ultra-wideband (UWB) channels by exploiting the fast movement of channel taps within delay bins. Considering the sparsity of UWB channels, we introduce a window-based CIR (WB-CIR) to approximate the high temporal resolutions of UWB channels. A recursive least square (RLS) algorithm is adopted to predict the time evolution of the WB-CIR. For predicting the future WB-CIR tap of window wk, three RLS filter coefficients are computed from the observed WB-CIRs of the left wk-1, the current wk and the right wk+1 windows...
2016: PloS One
https://www.readbyqxmd.com/read/27989529/a-fast-iterative-recursive-least-squares-algorithm-for-wiener-model-identification-of-highly-nonlinear-systems
#20
Mahdi Kazemi, Mohammad Mehdi Arefi
In this paper, an online identification algorithm is presented for nonlinear systems in the presence of output colored noise. The proposed method is based on extended recursive least squares (ERLS) algorithm, where the identified system is in polynomial Wiener form. To this end, an unknown intermediate signal is estimated by using an inner iterative algorithm. The iterative recursive algorithm adaptively modifies the vector of parameters of the presented Wiener model when the system parameters vary. In addition, to increase the robustness of the proposed method against variations, a robust RLS algorithm is applied to the model...
December 15, 2016: ISA Transactions
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