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https://www.readbyqxmd.com/read/27921322/the-heterophoria-of-3-5-year-old-children-as-a-function-of-viewing-distance-and-target-type
#1
Mary E Troyer, Vidhyapriya Sreenivasan, T J Peper, T Rowan Candy
PURPOSE: Heterophoria is the misalignment of the eyes in monocular viewing and represents the accuracy of vergence driven by all classical cues except disparity. It is challenging to assess restless children using clinical cover tests, and phoria in early childhood is poorly understood. Here we used eye tracking to assess phoria as a function of viewing distance and target in adults and young children, with comparison to clinical cover tests. METHODS: Purkinje image tracking (MCS PowerRefractor) was used to record eye alignment in adults (19-28 years, N = 24) and typically developing children (3-5 years, N = 24)...
December 5, 2016: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/27918087/fatigue-in-an-adult-attention-deficit-hyperactivity-disorder-population-a-trans-diagnostic-approach
#2
Denise C Rogers, Antonia J Dittner, Katharine A Rimes, Trudie Chalder
OBJECTIVES: Trans-diagnostic approaches suggest that key cognitive and behavioural processes maintain symptoms across a wide range of mental health disorders. Fatigue is a common clinical feature of attention deficit hyperactivity disorder (ADHD) in adulthood; however, empirical data supporting its prevalence are lacking. This study aimed to collate outcomes from outpatient services to (1) investigate the prevalence of fatigue in adults with ADHD, (2) examine symptoms of ADHD in adults with chronic fatigue syndrome (CFS), and (3) consider secondary clinical characteristics common to both disorder groups...
December 5, 2016: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/27914903/cognitive-behavioural-therapy-and-short-term-psychoanalytical-psychotherapy-versus-a-brief-psychosocial-intervention-in-adolescents-with-unipolar-major-depressive-disorder-impact-a-multicentre-pragmatic-observer-blind-randomised-controlled-superiority-trial
#3
Ian M Goodyer, Shirley Reynolds, Barbara Barrett, Sarah Byford, Bernadka Dubicka, Jonathan Hill, Fiona Holland, Raphael Kelvin, Nick Midgley, Chris Roberts, Rob Senior, Mary Target, Barry Widmer, Paul Wilkinson, Peter Fonagy
BACKGROUND: Psychological treatments for adolescents with unipolar major depressive disorder are associated with diagnostic remission within 28 weeks in 65-70% of patients. We aimed to assess the medium-term effects and costs of psychological therapies on maintenance of reduced depression symptoms 12 months after treatment. METHODS: We did this multicentre, pragmatic, observer-blind, randomised controlled superiority trial (IMPACT) at 15 National Health Service child and adolescent mental health service (CAMHS) clinics in three regions in England...
November 30, 2016: Lancet Psychiatry
https://www.readbyqxmd.com/read/27913463/single-dose-intravenous-iron-for-iron-deficiency-a-new-paradigm
#4
Michael Auerbach, Thomas Deloughery
Iron-deficiency anemia is the most common hematologic problem in the world. Although oral iron is often viewed as front-line therapy, extensive published evidence has accumulated that IV iron is superior, in both efficacy and safety, to oral iron in many clinical situations and should be introduced much sooner in the treatment paradigm of iron-deficient patients. In this chapter, we will review the formulations of IV iron that allow total complete replacement doses in 1 or 2 sessions including practical tips for administration...
December 2, 2016: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/27908587/higher-nocturnal-systolic-blood-pressure-in-patients-with-restless-legs-syndrome-compared-with-patients-with-insomnia
#5
Mariusz Sieminski, Kamil Chwojnicki, Markku Partinenen
BACKGROUND: There is evidence linking restless legs syndrome (RLS) with increased blood pressure (BP), but the mechanism of this relation remains unclear. Is the BP increased due to some features of RLS or to deterioration of sleep caused by RLS? This study compared values of nocturnal BP in patients with RLS and patients with insomnia. If increased BP in RLS is a consequence of disordered sleep, then it should be similar to increased BP in insomnia. METHODS: Polysomnographic recordings of patients admitted to a sleep center with RLS or insomnia were analyzed...
November 1, 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27908262/sleep-alterations-in-non-demented-older-individuals-the-role-of-cortisol
#6
Ana Belén Castelló-Domenech, Vanessa Ibáñez Del Valle, Julio Fernández-Garrido, Mary Martínez-Martínez, Omar Cauli
BACKGROUND: Sleep alterations can impair quality of life and contribute to disease progression but they, and their features and contributing factors, are rarely analysed in institutionalised older individuals. In this study we investigated sleep alterations, the factors involved, and the role of cortisol in sleep-related problems in institutionalised individuals. METHODS: We conducted a descriptive cross-sectional study in participants living in nursing homes in Valencia (Spain); sleep alterations were determined based on two validated tools: the Athens insomnia scale and Oviedo sleep questionnaire...
November 30, 2016: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/27899234/in-search-of-alternatives-to-dopaminergic-ligands-for-the-treatment-of-restless-legs-syndrome-iron-glutamate-and-adenosine
#7
REVIEW
Sergi Ferré, Christopher Earley, Seema Gulyani, Diego Garcia-Borreguero
Dopaminergic drugs have been used as the first-line treatment for restless legs syndrome (RLS) for many years and are considered to be, at least over the short-term, effective and safe. However, the main long-term complication of dopaminergic treatment is augmentation, which is an overall increase in symptom severity and intensity, with symptoms starting earlier in the afternoon and expanding to previously unaffected parts of the body. Augmentation is a common complication, with prevalence rates of nearly 50%, and is a common cause of treatment failure...
November 1, 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27894926/special-issue-advances-in-scientific-understanding-of-the-restless-legs-syndrome-rls-aka-willis-ekbom-disease-wed-introduction-towards-a-better-understanding-of-the-science-of-rls-wed
#8
EDITORIAL
Diego Garcia Borreguero, Juliane Winkelman, Richard P Allen
No abstract text is available yet for this article.
October 28, 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27894466/relationships-between-adult-emotional-states-and-indicators-of-health-care-utilization-findings-from-the-national-health-interview-survey-2006-2014
#9
Judith D Weissman, David Russell, Jeannette Beasley, Melanie Jay, Dolores Malaspina
OBJECTIVE: Adults with serious psychological distress have a high likelihood of mental health problems severe enough to cause serious impairment in social and occupational functioning requiring treatment. These adults visit doctors frequently yet have poor health compared to adults without serious psychological distress. This study examined associations between emotional states of serious psychological distress in relationship to healthcare utilization indicators. A guiding hypothesis was that somatization underlying emotional states contributes to excessive healthcare seeking among adults with serious psychological distress...
December 2016: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/27893817/the-impact-of-group-size-on-welfare-indicators-of-ewes-during-pregnancy
#10
Xavier Averós, Ignacia Beltrán de Heredia, Roberto Ruiz, Inma Estevez
Group size (GS) and space allowance have major implications for the welfare of production species, however their effects are often confounded. In a previous study we investigated the impact of varying space allowance at constant GS. In the present work we report the consequences of varying GS on pregnant ewes while controlling space allowance. We housed ewes at 6 (GS6) or 12 ewes/enclosure (GS12), while controlling space allowance to 1.5 m2/ewe (3 enclosures/treatment), and necessarily varying enclosure size...
2016: PloS One
https://www.readbyqxmd.com/read/27893699/nivolumab-induced-severe-akathisia-in-an-advanced-lung-cancer-patient
#11
Jiro Abe, Taku Sato, Ryota Tanaka, Toshimasa Okazaki, Satomi Takahashi
BACKGROUND Nivolumab is an anti-PD-1 immune checkpoint inhibitor that was recently developed for cancer immunotherapy. In the clinical trials of nivolumab, its adverse effects were reported to be less likely than those of conventional anti-cancer agents; however, after practical clinical distribution, it has come to be known that nivolumab induces various immune-related adverse events. CASE REPORT A 58-year-old male with a recurrence of lung adenocarcinoma was treated with nivolumab. Only four days after the initial administration of nivolumab, the patient presented with unbearable restlessness and distress that was resistant to all therapeutic agents used, and it gradually became worse...
November 23, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27890390/world-association-of-sleep-medicine-wasm-2016-standards-for-recording-and-scoring-leg-movements-in-polysomnograms-developed-by-a-joint-task-force-from-the-international-and-the-european-restless-legs-syndrome-study-groups-irlssg-and-eurlssg
#12
R Ferri, S Fulda, R P Allen, M Zucconi, O Bruni, S Chokroverty, L Ferini-Strambi, B Frauscher, D Garcia-Borreguero, M Hirshkowitz, B Högl, Y Inoue, A Jahangir, M Manconi, C L Marcus, D L Picchietti, G Plazzi, J W Winkelman, R S Zak
This report presents the results of the work by a joint task force of the International and European Restless Legs Syndrome Study Groups and World Association of Sleep Medicine that revised and updated the current standards for recording and scoring leg movements (LM) in polysomnographic recordings (PSG). First, the background of the decisions made and the explanations of the new rules are reported and then specific standard rules are presented for recording, detecting, scoring and reporting LM activity in PSG...
November 7, 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27889922/haloperidol-for-long-term-aggression-in-psychosis
#13
REVIEW
Abha Khushu, Melanie J Powney
BACKGROUND: Psychotic disorders can lead some people to become agitated. Characterised by restlessness, excitability and irritability, this can result in verbal and physically aggressive behaviour - and both can be prolonged. Aggression within the psychiatric setting imposes a significant challenge to clinicians and risk to service users; it is a frequent cause for admission to inpatient facilities. If people continue to be aggressive it can lengthen hospitalisation. Haloperidol is used to treat people with long-term aggression...
November 27, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27889491/pramipexole-enhances-disadvantageous-decision-making-lack-of-relation-to-changes-in-phasic-dopamine-release
#14
Romina Pes, Sean C Godar, Andrew T Fox, Lauren M Burgeno, Hunter J Strathman, David P Jarmolowicz, Paola Devoto, Beth Levant, Paul E Phillips, Stephen C Fowler, Marco Bortolato
Pramipexole (PPX) is a high-affinity D2-like dopamine receptor agonist, used in the treatment of Parkinson's disease (PD) and restless leg syndrome. Recent evidence indicates that PPX increases the risk of problem gambling and impulse-control disorders in vulnerable patients. Although the molecular bases of these complications remain unclear, several authors have theorized that PPX may increase risk propensity by activating presynaptic dopamine receptors in the mesolimbic system, resulting in the reduction of dopamine release in the nucleus accumbens (NAcc)...
November 23, 2016: Neuropharmacology
https://www.readbyqxmd.com/read/27878605/-special-medical-problems-in-end-of-life-care-crisis-at-the-end-of-life-which-therapy-is-adequate-and-when-is-redefining-treatment-goals-appropriate
#15
Gesine Benze, Bernd Alt-Epping, Friedemann Nauck
Crisis at the end of life are exceptional challenges for patients, relatives and therapists. With respect to the individual treatment goals and the patients' autonomy, therapeutic action should be commenced in an adequate manner in order to preserve the patients' quality of life as much as possible. Advance care planning for specific critical scenarios may be helpful in order to treat patients according to their wishes and values even if they are not capable to express themselves. Furthermore, a crisis plan can define the scope of action for therapists in emergency situations...
November 23, 2016: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/27876982/prevalence-of-enterobius-vermicularis-infection-among-preschool-children-babol-north-of-iran
#16
Seyed Ali Norbakhsh Amiri, Mohammad Taghi Rahimi, Seif Ali Mahdavi, Mahmood Moosazadeh, Omid Ramzani, Ali Farrokhi Koshk, Reza Rosbehan, Seyed Abolghasem Siyadatpanah
Enterobius vermicularis or pinworm, is considered as one of the most frequently encountered intestinal nematodes and infects millions of people throughout the world particularly children. Some symptoms of the infection including Anal itching, restlessness, insomnia, endometritis, abdominal cramps, diarrhea and etc. The purpose of the present study was to determine the status of enterobiasis in kindergarten and preschool children of kindergartens from Amir Kola, Babol Mazandaran Province, North of Iran. A total number of 126 (70 boys and 56 girls) children from four kindergartens from Amir Kola, Babol, Mazandaran Province, North of Iran were examined for the prevalence of E...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27876942/prevalence-of-enterobius-vermicularis-amongst-kindergartens-and-preschool-children-in-mazandaran-province-north-of-iran
#17
Narges Afrakhteh, Zahra Marhaba, Seif Ali Mahdavi, Sahar Garoosian, Reyhaneh Mirnezhad, Mahsa Eshkevar Vakili, Haniye Ahmadi Shahraj, Behzad Javadian, Rozita Rezaei, Mahmood Moosazadeh
Enterobiasis (oxyuriasis) is probably the most common helminth, which infects humans. Amongst different age groups, prevalence of Enterobius vermicularis in children is high compared to adults. Oxyuriasis is one of the most significant parasitic diseases of children. This nematode in children can result in loss of appetite, insomnia, grinding of the teeth, restlessness, endometritis, abdominal cramps, diarrhea and etc. Due to important complications of this parasite, the objective of the current study was to determine the prevalence of enterobiasis in kindergarten and preschool children of Amol, Mazandaran Province, North of Iran...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27863901/a-systematic-review-of-the-literature-on-disorders-of-sleep-and-wakefulness-in-parkinson-s-disease-from-2005-to-2015
#18
REVIEW
Lama M Chahine, Amy W Amara, Aleksandar Videnovic
Sleep disorders are among the most common non-motor manifestations in Parkinson's disease (PD) and have a significant negative impact on quality of life. While sleep disorders in PD share most characteristics with those that occur in the general population, there are several considerations specific to this patient population regarding diagnosis, management, and implications. The available research on these disorders is expanding rapidly, but many questions remain unanswered. We thus conducted a systematic review of the literature published from 2005 to 2015 on the following disorders of sleep and wakefulness in PD: REM sleep behavior disorder, insomnia, nocturia, restless legs syndrome and periodic limb movements, sleep disordered breathing, excessive daytime sleepiness, and circadian rhythm disorders...
August 31, 2016: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/27856776/practice-guideline-summary-treatment-of-restless-legs-syndrome-in-adults-report-of-the-guideline-development-dissemination-and-implementation-subcommittee-of-the-american-academy-of-neurology
#19
John W Winkelman, Melissa J Armstrong, Richard P Allen, K Ray Chaudhuri, William Ondo, Claudia Trenkwalder, Phyllis C Zee, Gary S Gronseth, David Gloss, Theresa Zesiewicz
OBJECTIVE: To make evidence-based recommendations regarding restless legs syndrome (RLS) management in adults. METHODS: Articles were classified per the 2004 American Academy of Neurology evidence rating scheme. Recommendations were tied to evidence strength. RESULTS AND RECOMMENDATIONS: In moderate to severe primary RLS, clinicians should consider prescribing medication to reduce RLS symptoms. Strong evidence supports pramipexole, rotigotine, cabergoline, and gabapentin enacarbil use (Level A); moderate evidence supports ropinirole, pregabalin, and IV ferric carboxymaltose use (Level B)...
November 16, 2016: Neurology
https://www.readbyqxmd.com/read/27855740/orthosomnia-are-some-patients-taking-the-quantified-self-too-far
#20
Kelly Glazer Baron, Sabra Abbott, Nancy Jao, Natalie Manalo, Rebecca Mullen
The use of wearable sleep tracking devices is rapidly expanding and provides an opportunity to engage individuals in monitoring of their sleep patterns. However, there are a growing number of patients who are seeking treatment for self-diagnosed sleep disturbances such as insufficient sleep duration and insomnia due to periods of light or restless sleep observed on their sleep tracker data. The patients' inferred correlation between sleep tracker data and daytime fatigue may become a perfectionistic quest for the ideal sleep in order to optimize daytime function...
November 14, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
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