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K Raoufinejad, P Mansouri, M Rajabi, Z Naraghi, R Jebraeili
BACKGROUND: Rosacea is a chronic, multifactorial, dermatological condition. Increased density of Demodex folliculorum mites in the skin of rosacea patients suggests a possible role for these mites in the pathophysiology of rosacea. OBJECTIVE: To evaluate the effects of permethrin 5% topical gel vs. placebo on Demodex density (Dd) and clinical presentations of rosacea patients, and also to further refine the quantitative assessment of Dd in the non-invasive standard skin surface biopsy (SSSB)...
September 7, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
E Cinotti, M Espinasse, B Labeille, F Cambazard, J L Perrot
A 33 year-old woman suffering from rosacea presented with outbreaks of itchy plaques on her face and limbs that curiously improved when she was far from home during summer holidays (Fig. 1). Dermoscopy (FotoFinder Systems GmbH, Bad Birnbach, Germany) showed petechiae (Fig. 2A) and reflectance confocal microscopy (RCM; Vivascope 3000(®) , Caliber, New York, USA, distributed in Europe by MAVIG GmbH, München, Germany) showed intraepidermal vesicles (Fig. 2B) suggesting parasite bites. RCM found Demodex folliculorum (Fig...
August 31, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
Fabienne M N Forton, Viviane De Maertelaer
Diagnosing papulopustular rosacea is not always straightforward; no specific diagnostic test is currently available. A high density of Demodex mites is consistently observed in this condition. This retrospective study assesses an improved method for evaluating Demodex density among 1,044 patients presenting to our dermatology practice. The skin was cleaned with ether and Demodex densities were measured in 2 consecutive standardized skin surface biopsies taken from the same site. Mean densities in patients with rosacea and demodicosis were much higher than those in healthy controls and patients with other facial dermatoses...
August 30, 2016: Acta Dermato-venereologica
Peter C Smith, Caroline J Zeiss, Amanda P Beck, Jodi A Scholz
Demodex musculi, a prostigmatid mite that has been reported infrequently in laboratory mice, has been identified with increasing frequency in contemporary colonies of immunodeficient mice. Here we describe 2 episodes of D. musculi infestation with associated clinical signs in various genetically engineered mouse strains, as well as treatment strategies and an investigation into transmissibility and host susceptibility. The first case involved D. musculi associated with clinical signs and pathologic lesions in BALB/c-Tg(DO11...
2016: Comparative Medicine
Yang Luo, Yu-Jiao Sun, Li Zhang, Xiu-Li Luan
OBJECTIVE: Treatment of Demodex infestations is often inadequate and associated with low effective rate. We sought to evaluate the efficacy of an ornidazole-based sequential therapy for mites folliculitis treatment. METHODS: Two-hundred patients with mites folliculitis were sequentially treated with either an ornidazole- or metronidazole-based regimen. Sebum cutaneum was extruded from the sebaceous glands of each patient's nose and the presence of Demodex mites were examined by light microscopy...
July 2016: Medicine (Baltimore)
Emine Unal, Ulviye Guvendi Akcinar, Yalcin Basaran
No abstract text is available yet for this article.
July 2016: Archives of Iranian Medicine
Josete Garcia Bersano, Márcia Cristina Mendes, Fernanda Calvo Duarte, Claudia Del Fava, Sueli Moda de Oliveira, Elizabeth Spósito Filha, Eliana Scarcelli Pinheiro, Alessandra Figueiredo de Castro Nassar, Maria Cristina de Vasconcellos Bilynskyj, Renato Akio Ogata, Paulo Henrique Selbmann Sampaio, Margareth Élide Genovez
This paper reports the occurrence of porcine demodicosis caused by the mite Demodex phylloides in hogs reared in a peri-urban family farm located in Francisco Morato, a municipality of the Metropolitan Region of São Paulo, capital city of the state of São Paulo, Brazil. In a parcel of forty Landrace - Large White cross hogs, approximately four months old, four animals presented severe skin lesions in the form of small nodules over their entire body, especially in the periocular region, snout, lower abdomen and flanks...
June 8, 2016: Veterinary Parasitology
A Tenorio-Abreu, J C Sánchez-España, L E Naranjo-González, M C González-Gallego, C Hidalgo-Grass, C Ruíz-Frutos
OBJECTIVE: To standardize the relative quantification by mass of tissue parasitism by Demodex folliculorum infestation from neoplastic skin biopsies periocular using molecular amplification to study the possible relationship of the appearance of eyelid basal cell carcinoma with the presence and density of the mite in later works. METHODS: A quantitative PCR was developed real-time probes TaqMan. PCR was tested in a pilot 46 actual biopsy samples nodular basal cell carcinoma series...
August 2016: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
Catherine Milley, Michael Dryden, Wayne Rosenkrantz, Joya Griffin, Christopher Reeder
OBJECTIVES: This study compared methods of mite retrieval from community cats in the Ohio River Valley region of the USA and determined incidence of parasitic mites in this region. METHODS: In total, 493 community cats were humanely trapped and anesthetized for a trap-neuter-return program. Cats received a dermatologic examination, ear swabs, superficial skin scraping, flea combing, acetate tape preparation and feces collection. All samples were examined microscopically...
June 3, 2016: Journal of Feline Medicine and Surgery
Ülkü Karaman, Zeynep Kolören, Özgür Enginyurt, Cemil Çolak
Demodex folliculorum and Demodex brevis are common ectoparasites in humans. Demodex parasite infestations have not been determined in the province of Ordu. We determined the prevalence of Demodex species among humans in Ordu Provience, Turkey. Seven hundred ninety-nine subjects (438 males and 361 females) aged ≥ 18 years living in the central districts of Ordu Province, Turkey, were selected using the World Health Organization cluster sampling method. A superficial skin biopsy of the face was obtained from each subject...
March 2016: Southeast Asian Journal of Tropical Medicine and Public Health
Hong Liang, Matthieu Randon, Sylvain Michee, Rachid Tahiri, Antoine Labbe, Christophe Baudouin
AIMS: The physiopathology of rosacea and the correlation between ocular and cutaneous rosacea remains unclear. This study analysed ocular and cutaneous rosacea with in vivo confocal microscopy (IVCM). METHODS: Thirty-four eyes of 34 patients with confirmed rosacea-associated meibomian gland dysfunction-related evaporative dry eye were enrolled in the study. The ophthalmological investigations included dry eye ocular surface disease index (OSDI), the Schirmer test, tear osmolarity, tear break up time, the Oxford score, infrared meibography for meibomian gland (MG) analysis and IVCM investigation for cornea, MG and skin analysis (cheek, hand)...
May 24, 2016: British Journal of Ophthalmology
Sigurlaug Gunnarsdottir, Arni Kristmundsson, Mark A Freeman, Olafur Mar Bjornsson, Gunnar Mar Zoega
UNLABELLED: Meibomian gland dysfunction (MGD) is a common cause of dry eye disease. Demodex mites can cause MGD with symptoms like itching, dryness and general ocular discomfort. It is important to consider infestation with Demodex mites in individuals who are non responsive to traditional MGD treatment but also equally important when cylindrical dandruff is seen at the base of the eye lashes.. We report two individuals who had not responded to ocular and systemic treatment for MGD and were then diagnosed with Demodex mites...
May 2016: Læknablađiđ
Stephen G Nicholls, Carmen L Oakley, Andrea Tan, Brendan J Vote
Demodex brevis and Demodex folliculorum are likely ubiquitous organisms associated with human eyelashes. However, they have also been implicated in the pathogenesis of external ocular diseases. This article reviews the current literature in regards to life cycle, morphology, pathogenesis and treatment of underlying Demodex spp. infestation and outlines the previously undescribed in vivo behaviour of the mites. Images were obtained from the epilation of lashes from 404 patients seen in clinical practice. Epilated lashes were placed on a microscope slide which had been coated with optically clear hypromellose/carbomer gel (Genteal gel, Novartis pharmaceuticals corporation, East Hanover, New Jersey)...
May 9, 2016: International Ophthalmology
X Y Zhang, X G Sun
Demodex blepharitis is an infectious ocular disease which is common, but always to be neglected. There were a few related reports about this disease in China. The pathogenic mechanism of demodex blepharitis is not clear at present. Literatures held different ideas about its diagnosis, therapeutic methods and curative effect. This review will summarize the new development of demodex blepharitis in order to provide references for its basic and clinical researches.(Chin J Ophthalmol, 2016, 52: 315-320).
April 11, 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
Kibeb Seid, Sisay Amare, Yacob Hailu Tolossa
A cross sectional study of small ruminant mange mites was conducted from November 2011 to April 2012 on a total of 324 sheep and 680 goats, to determine the prevalence of mange mites in sheep and goats, identifying the major species of mite and to determine the potential risk factors significantly predicting the disease. The result showed an overall mange mite prevalence of 7.5 % (95 % CI 5.5-9.5) in goats and 1.2 % (95 % CI 0.5-1.9) in sheep. The mites identified were Sarcoptes and Demodex in goats and Sarcoptes and Psoroptes in sheep...
March 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
Leah A Cardwell, Hossein Alinia, Sara Moradi Tuchayi, Steven R Feldman
Rosacea is a chronic dermatological disorder with a variety of clinical manifestations localized largely to the central face. The unclear etiology of rosacea fosters therapeutic difficulty; however, subtle clinical improvement with pharmacologic treatments of various drug categories suggests a multifactorial etiology of the disease. Factors that may contribute to disease pathogenesis include immune abnormality, vascular abnormality, neurogenic dysregulation, presence of cutaneous microorganisms, UV damage, and skin barrier dysfunction...
2016: Clinical, Cosmetic and Investigational Dermatology
Claudia Salvadori, Nicoletta Formenti, Tiziana Trogu, Paolo Lanfranchi, Roberto A Papini, Alessandro Poli
We report demodicosis in five alpine chamois ( Rupicapra rupicapra subsp. rupicapra) from the Italian Alps that showed moderate crusts on the head and dorsal aspect of the trunk. We detected intramural folliculitis, moderate dermatitis, and T-lymphocytes and macrophages associated with Demodex spp. in follicles and sebaceous glands.
April 28, 2016: Journal of Wildlife Diseases
Robert H Six, Csilla Becskei, Mark M Mazaleski, Josephus J Fourie, Sean P Mahabir, Melanie R Myers, Nathalie Slootmans
The efficacy of sarolaner (Simparica™, Zoetis) was evaluated against Demodex spp. in dogs with generalized demodicosis and against Otodectes cynotis (otodectic mange) in dogs with induced infestations. In the first study, 16 dogs with clinical signs of generalized demodicosis and positive for Demodex spp. mites were randomly assigned to treatment with either sarolaner (2mg/kg) orally on Days 0, 30 and 60, or topical imidacloprid (10mg/kg) plus moxidectin (2.5mg/kg) solution every 7 days from Day 0 to Day 81...
May 30, 2016: Veterinary Parasitology
Asli Turgut Erdemir, Mehmet Salih Gurel, Ayse Esra Koku Aksu, Tugba Falay, Esma Inan Yuksel, Ebru Sarikaya
BACKGROUND/OBJECTIVES: Demodex mite density is emphasised in the aetiopathogenesis of acne rosacea. Reflectance confocal microscopy (RCM) has been shown to be a good method for determining demodex mite density. The objective was to determine demodex mite density using RCM in acne rosacea patients and compare them with controls. METHODS: In all, 30 papulopustular rosacea (PPR) and 30 erythematotelangiectatic rosacea (ETR) totally 60 acne rosacea patients and 40 controls, were enrolled in the study...
March 11, 2016: Australasian Journal of Dermatology
Wissam Helou, Emily Avitan-Hersh, Reuven Bergman
Demodex is a saprophytic mite in humans commonly present in the pilosebaceous units, which has been implicated as a pathogen in several skin conditions. The clinical presentation and histopathology of Demodex folliculitis of the scalp have been described in only a few case reports. This study was performed to further elucidate the clinicopathological features of this entity. We have studied 333 consecutively submitted scalp biopsies performed for hair loss and alopecia. All specimens were completely step-sectioned...
September 2016: American Journal of Dermatopathology
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