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https://www.readbyqxmd.com/read/29035242/the-effect-of-skin-sebum-ph-and-moisture-on-demodex-infestation-in-acne-vulgaris-and-rosacea-patients
#1
Nergiz Turan, Yelda Kapıcıoğlu, Gülbahar Saraç
OBJECTIVE: Acne vulgaris is an inflammatory disease involving the pilosebaceous unit. Rosacea is a chronic inflammatory skin disease that affects the face in particular. This study aimed to determine if skin sebum, pH, and moisture affect the number of Demodex spp. in acne vulgaris and rosacea patients. METHODS: This study focused on 30 patients each with acne vulgaris and rosacea. As a control group, 60 healthy individuals were included. RESULTS: In acne vulgaris patients, when compared to those with Demodex mite more than 5 /cm2 in each area, less than 5/cm2 were found to be oily, acidic, dry or very dry...
September 2017: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/29032499/dna-barcoding-for-molecular-identification-of-demodex-based-on-mitochondrial-genes
#2
Li Hu, YuanJun Yang, YaE Zhao, DongLing Niu, Rui Yang, RuiLing Wang, Zhaohui Lu, XiaoQi Li
There has been no widely accepted DNA barcode for species identification of Demodex. In this study, we attempted to solve this issue. First, mitochondrial cox1-5' and 12S gene fragments of Demodex folloculorum, D. brevis, D. canis, and D. caprae were amplified, cloned, and sequenced for the first time; intra/interspecific divergences were computed and phylogenetic trees were reconstructed. Then, divergence frequency distribution plots of those two gene fragments were drawn together with mtDNA cox1-middle region and 16S obtained in previous studies...
October 14, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28945649/short-term-comfort-responses-associated-with-the-use-of-eyelid-cleansing-products-to-manage-demodex-folliculorum
#3
William Ngo, Lyndon Jones, Etty Bitton
PURPOSE: To quantify the discomfort over time of various eyelid cleansers against Demodex. METHODS: This was a prospective, randomized, controlled, crossover, open-label study that enrolled 26 participants. The cleansers used in this study were Biotissue Cliradex (CD), OCuSOFT Lid Scrubs Plus (OP), OCuSOFT OUST Demodex Swabstix (ODS), TheraTears Theralid (TT), NovaBay Avenova (NA). Bausch+Lomb Sensitive Eyes Plus saline was used as a control. Participants were asked to close their eyes as the product was gently rubbed (10 cycles of gentle lateral motion) into the eyelashes...
September 21, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28940244/demodicosis-in-two-patients-with-a-previous-history-of-langerhans-cell-histiocytosis
#4
Marcial Álvarez-Salafranca, Asunción Vicente, Carolina Prat Torres, Andrea Combalia, Manuel Monsonís, Veronica Paola Celis-Passini, María Antonia González-Enseñat
Demodex mites are commensal organisms rarely found in healthy children. Human demodicosis can be classified as a primary or a secondary form. The secondary form in children usually affects severely immunodepressed children. To our knowledge, this is the first report of human demodicosis associated with Langerhans cell histiocytosis. These cases show that this skin disorder can occur months after completing chemotherapy, without recurrence of the systemic disease.
September 21, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28938925/demodex-clusters
#5
Chantal Favier
No abstract text is available yet for this article.
October 2017: Ophthalmology
https://www.readbyqxmd.com/read/28926882/-diagnostic-criteria-of-demodex-blepharitis
#6
L Y Liang, J Li, Y Liu
Demodex infestation is a common cause of blepharitis and now is drawing more and more attention from clinicians. Demodex mite is the most common age-related ectoparasite of human being and may be detected from asymptomatic normal population. Furthermore, the pathogenesis of demodicosis remains unclear. Therefore, the commonly accepted diagnostic criteria of demodex infestation related blepharitis have not been established. Herein, we summarize the related studies about ocular demodicosis and comment the debates about the diagnosis of the disease...
September 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28920478/pityriasis-folliculorum-of-the-back-thoracic-area-pityrosporum-keratin-plugs-or-demodex-involved
#7
Alin Laurentiu Tatu, Violeta Corina Cristea
No abstract text is available yet for this article.
September 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28902017/ocular-demodicosis-as-a-potential-cause-of-ocular-surface-inflammation
#8
Xiaohui Luo, Jing Li, Chuan Chen, Scheffer Tseng, Lingyi Liang
Among different species of mites, Demodex folliculorum and Demodex brevis are the only 2 that affect the human eye. Because demodicosis is highly age-dependent and can be found in asymptomatic adults, the pathogenicity of these mites has long been debated. In this study, we summarize our research experience including our most recent study regarding Demodex infestation as a potential cause of ocular inflammatory diseases. Specifically, we describe the pathogenesis of demodicosis and then discuss the results of work investigating the associations and relationships between ocular demodicosis and blepharitis, meibomian gland diseases, and keratitis, in turn...
November 2017: Cornea
https://www.readbyqxmd.com/read/28868794/canine-demodicosis-a-retrospective-study-of-a-veterinary-hospital-population-in-california-usa-2000-2016
#9
Daniel G Bowden, Catherine A Outerbridge, Marguerite B Kissel, Jerome N Baron, Stephen D White
BACKGROUND: Demodex spp. are cutaneous mites that cause clinical disease when present in increased numbers. There is an association in some dogs with underlying systemic disease or immunosuppressive medications. HYPOTHESIS/OBJECTIVES: Retrospective study to document breed predisposition, identify any concurrent diseases or underlying immunosuppressive conditions, and to determine the frequency of demodicosis recurrence after treatment completion. ANIMALS: There were 431 dogs with demodicosis presented to a veterinary teaching hospital in California, USA, from 2000 to 2016...
September 3, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28846817/the-usefulness-of-investigating-the-possible-underlying-conditions-in-rosacea
#10
G Ciccarese, A Parodi, A Rebora, F Drago
The paper entitled "Rosacea and demodicidosis with gain of function mutation in STAT1″ by Second et al.(1) is of indubitable interest and prompted us to make some observations. The Authors described a patient with cutaneous and ocular rosacea that they related to demodicidosis since oral ivermectin improved the cutaneous lesions(1) . However, the Authors did not demonstrate by skin scraping nor by standardized skin surface biopsy (SSSB) an excessive number of Demodex folliculorum (DF) mites in the pilosebaceous units to justify an oral antiparasitic treatment as a drug of first choice(1) ...
August 28, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28830578/characterization-of-demodex-musculi-infestation-associated-comorbidities-and-topographic-distribution-in-a-mouse-strain-with-defective-adaptive-immunity
#11
Melissa A Nashat, Kerith R Luchins, Michelle L Lepherd, Elyn R Riedel, Joanna N Izdebska, Neil S Lipman
A colony of B6.Cg-Rag1tm1Mom Tyrp1B-w Tg(Tcra,Tcrb)9Rest (TRP1/TCR) mice presented with ocular lesions and ulcerative dermatitis. Histopathology, skin scrapes, and fur plucks confirmed the presence of Demodex spp. in all clinically affected and subclinical TRP1/TCR mice examined (n = 48). Pasteurella pneumotropica and Corynebacterium bovis, both opportunistic pathogens, were cultured from the ocular lesions and skin, respectively, and bacteria were observed microscopically in abscesses at various anatomic locations (including retroorbital sites, tympanic bullae, lymph nodes, and reproductive organs) as well as the affected epidermis...
August 1, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28822351/granulomatous-rosacea-a-case-report
#12
A Kelati, F Z Mernissi
BACKGROUND: Granulomatous rosacea is a rare chronic inflammatory skin disease with an unknown origin. The role of Demodex follicularum in its pathogenesis is currently proved. CASE PRESENTATION: We report a case of a 54-year-old Moroccan man with a 3-month history of erythematous, nonpruritic papules on the lateral side around the eyes. Dermoscopy and histology confirmed the diagnosis of granulomatous rosacea. CONCLUSIONS: We describe another clinical presentation of granulomatous rosacea with a clinical-dermoscopic-pathological correlation...
August 20, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28761482/molecular-characterization-and-analysis-of-16s-ribosomal-dna-in-some-isolates-of-demodex-folicullorum
#13
Afrooz Daneshparvar, Gholamreza Mowlavi, Hamed Mirjalali, Homa Hajjaran, Iraj Mobedi, Saeed Reza Naddaf, Mohammadreza Shidfar, Mahsa Sadat Makki
BACKGROUND: Demodicosis is one of the most prevalent skin diseases resulting from infestation by Demodex mites. This parasite usually inhabits in follicular infundibulum or sebaceous duct and transmits through close contact with an infested host. METHODS: This study was carried from September 2014 to January 2016 at Tehran University of Medical Sciences, Tehran, Iran. DNA extraction and amplification of 16S ribosomal RNA was performed on four isolates, already obtained from four different patients and identified morphologically though clearing with 10% Potassium hydroxide (KOH) and microscopical examination...
April 2017: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28747952/human-permanent-ectoparasites-recent-advances-on-biology-and-clinical-significance-of-demodex-mites-narrative-review-article
#14
REVIEW
Dorota Litwin, WenChieh Chen, Ewa Dzika, Joanna Korycińska
BACKGROUND: Demodex is a genus of mites living predominantly in mammalian pilosebaceous units. They are commonly detected in the skin of face, with increasing numbers in inflammatory lesions. Causation between Demodex mites and inflammatory diseases, such as rosacea, blepharitis, perioral and seborrhoeic dermatitis or chalazion, is controversially discussed. Clinical observations indicate a primary form of human Demodex infection. The aim of this review was to highlight the biological aspects of Demodex infestation and point out directions for the future research...
January 2017: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28728857/-rosacea-new-data-for-better-care
#15
B Cribier
In the last 10 years, numerous studies have been published that throw new light on rosacea, in all areas of the disease. This overview summarises all the key developments, based on the indexed bibliography appearing in Medline between 2007 and 2017. Recent epidemiological data show that the prevalence of the disease is doubtless greater than estimated hitherto (more than 10% of adults in some countries) and that we should not overlook rosacea in subjects with skin phototypes V or VI, a condition that exists on all continents...
August 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28711190/role-of-demodex-mite-infestation-in-rosacea-a-systematic-review-and-meta-analysis
#16
REVIEW
Yin-Shuo Chang, Yu-Chen Huang
BACKGROUND: The reported prevalence and degrees of Demodex mite infestation in rosacea vary widely. OBJECTIVE: We sought to conduct an evidence-based meta-analysis of the prevalence and degrees of Demodex mite infestation in patients with rosacea. METHODS: Systematic literature review and meta-analysis were conducted. Odds ratios for prevalence of infestation and standardized mean difference (SMD) for Demodex density in patients with rosacea were pooled...
September 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28696955/pediatric-blepharokeratoconjunctivitis-is-there-a-right-treatment
#17
REVIEW
Sepideh T Rousta
PURPOSE OF REVIEW: This article highlights the importance of recognizing blepharokeratoconjunctivitis (BKC) in children and reviews the clinical characteristics and current therapeutic modalities. RECENT FINDINGS: The mainstay of BKC treatment remains controlling the meibomian gland inflammation and treating cobormid conditions. BKC can occur in the setting of ocular rosacea and Demodex infestation. Small studies have shown treatment benefits of topical cyclosporine A as well as oral azithromycin in pediatric BKC...
September 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28695831/demodex-species-infestation-in-patients-with-ear-itching-and-its-relationship-to-itch-severity
#18
Nagihan Bilal, Özlem Kirişci, Esra Özkaya
OBJECTIVE: The aim of the present study was to investigate Demodex species infestation in patients with ear itching. The relationship between the severity of ear itching and Demodex spp. positivity has not been previously reported in the literature, and we believe that our study will make a significant contribution to the understanding of the etiology of ear itching. METHODS: Fifty patients with itching ears and 54 healthy control patients were asked to use a visual analogue scale (VAS) to rate the itch, the itching period, and the medication used for the itching...
June 2017: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/28695830/prevalence-and-density-of-demodex-folliculorum-and-demodex-brevis-acari-demodicidae-in-erzincan-province
#19
Engin Tilki, Erhan Zeytun, Salih Doğan
OBJECTIVE: This study aimed to determine the prevalence and density of Demodex folliculorum and D. brevis in Erzincan Province and the association between Demodex spp. and skin moisture, pH, and temperature. METHODS: The study included total 300 healthy participants without dermatological ailments and residing in Erzincan Province. Moisture, pH, and temperature of the cheek were measured, and the presence of mite was determined in samples from the cheek, nasolabial, and chin region using the standard superficial skin biopsy technique...
June 2017: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/28653460/dual-anti-inflammatory-and-anti-parasitic-action-of-topical-ivermectin-1-in-papulopustular-rosacea
#20
M Schaller, L Gonser, K Belge, C Braunsdorf, R Nordin, A Scheu, C Borelli
BACKGROUND: Recently, therapy of rosacea with inflammatory lesions (papulopustular) has improved substantially with the approval of topical ivermectin 1% cream. It is assumed to have a dual mode of action with anti-inflammatory capacities and anti-parasitic effects against Demodex, which however has not yet been demonstrated in vivo. AIM: To find scientific rationale for the dual anti-inflammatory and anti-parasitic mode of action of topical ivermectin 1% cream in patients with rosacea...
June 27, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
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