Jake J Son, Yasra Arif, Davina Oludipe, Lucas Weyrich, Abraham D Killanin, Alex I Wiesman, Hannah J Okelberry, Madelyn P Willett, Hallie J Johnson, Tony W Wilson
Hypertension-related changes in brain function place individuals at higher risk for cognitive impairment and Alzheimer's disease. The existing functional neuroimaging literature has identified important neural and behavioural differences between normotensive and hypertensive individuals. However, previously-used methods (i.e. magnetic resonance imaging, functional near-infrared spectroscopy) rely on neurovascular coupling, which is a useful but indirect measure of neuronal activity. Furthermore, most studies fail to distinguish between controlled and uncontrolled hypertensive individuals, who exhibit significant behavioural and clinical differences...
March 22, 2024: Journal of Physiology