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https://www.readbyqxmd.com/read/28649194/seeing-double-exploring-the-phenomenology-of-self-reported-absence-of-rivalry-in-bistable-pictures
#1
Elisa Filevich, Maxi Becker, Yuan-Hao Wu, Simone Kühn
Ambiguous images such as Rubin's vase-face can be interpreted in at least two different ways. These interpretations are typically taken to be mutually exclusive, and ambiguous images have thus served as models of perceptual competition. Here, we present data that challenges this view. In an online survey, we found that a large proportion of people within the general population reported that the two percepts were not competing but could be perceived simultaneously. Of those who reported that they could see both percepts simultaneously, we invited 17 participants to take part in a functional magnetic resonance imaging (fMRI) experiment...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28647536/crhr1-exacerbates-the-glial-inflammatory-response-and-alters-bdnf-trkb-pcreb-signaling-in-a-rat-model-of-global-cerebral-ischemia-implications-for-neuroprotection-and-cognitive-recovery
#2
Patricia B de la Tremblaye, Simon M Benoit, Sarah Schock, Hélène Plamondon
This study examined the impact of corticotropin-releasing hormone type 1 receptor (CRHR1) blockade using Antalarmin (ANT) on the expression of markers of neuroplasticity and inflammation, as well as neuroprotection and behavioral recovery following global cerebral ischemia. Male Wistar rats (N=50) were treated with ANT (2μg/2μl; icv) or a vehicle solution prior to a sham or four vessel (4VO) occlusion. Seven days post ischemia, anxiety was assessed in the Elevated Plus Maze and Open Field tests, and fear and spatial learning in a Y-Maze Passive Avoidance Task and the Barnes Maze...
June 21, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28642695/concealed-around-the-ear-eeg-captures-cognitive-processing-in-a-visual-simon-task
#3
Marlene Pacharra, Stefan Debener, Edmund Wascher
In theory, miniaturized systems such as the around-the-ear electrode arrays (cEEGrids) enable mobile monitoring of the electroencephalogram (EEG) in a variety of real life situations without interfering with the natural setting. However, the research benefit of such cEEGrid recordings critically depends on their validity. To investigate whether visual and motor processing are reflected in the cEEGrid-EEG, a direct comparison of EEG that was concurrently recorded with the cEEGrids and with a high-density cap setup was conducted...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28640798/evaluation-of-placental-and-fetal-tissue-specimens-for-zika-virus-infection-50-states-and-district-of-columbia-january-december-2016
#4
Sarah Reagan-Steiner, Regina Simeone, Elizabeth Simon, Julu Bhatnagar, Titilope Oduyebo, Rebecca Free, Amy M Denison, Demi B Rabeneck, Sascha Ellington, Emily Petersen, Joy Gary, Gillian Hale, M Kelly Keating, Roosecelis B Martines, Atis Muehlenbachs, Jana Ritter, Ellen Lee, Alexander Davidson, Erin Conners, Sarah Scotland, Kayleigh Sandhu, Andrea Bingham, Elizabeth Kassens, Lou Smith, Kirsten St George, Nina Ahmad, Mary Tanner, Suzanne Beavers, Brooke Miers, Kelley VanMaldeghem, Sumaiya Khan, Ingrid Rabe, Carolyn Gould, Dana Meaney-Delman, Margaret A Honein, Wun-Ju Shieh, Denise J Jamieson, Marc Fischer, Sherif R Zaki
Zika virus infection during pregnancy can cause congenital microcephaly and brain abnormalities (1), and detection of Zika virus RNA in clinical and tissue specimens can provide definitive laboratory evidence of recent Zika virus infection. Whereas duration of viremia is typically short, prolonged detection of Zika virus RNA in placental, fetal, and neonatal brain tissue has been reported and can provide key diagnostic information by confirming recent Zika virus infection (2). In accordance with recent guidance (3,4), CDC provides Zika virus testing of placental and fetal tissues in clinical situations where this information could add diagnostic value...
June 23, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28639796/modality-switching-in-the-simon-task-the-clash-of-reference-frames
#5
Manuela Ruzzoli, Salvador Soto-Faraco
The representation of spatial information related to an event can influence behavior even when location is task-irrelevant, as in the case of Stimulus-Response (S-R) compatibility effects on the Simon task. However, unlike single-modality situations, which are often used to study the Simon effect, in real-life scenarios various sensory modalities provide spatial information coded in different coordinate systems. Here, we address the expression of S-R compatibility effects in mixed-modality contexts, where events can occur in 1 of various sensory modalities (i...
June 22, 2017: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/28635378/people-with-autism-spectrum-conditions-make-more-consistent-decisions
#6
George D Farmer, Simon Baron-Cohen, William J Skylark
People with autism spectrum conditions (ASC) show reduced sensitivity to contextual stimuli in many perceptual and cognitive tasks. We investigated whether this also applies to decision making by examining adult participants' choices between pairs of consumer products that were presented with a third, less desirable "decoy" option. Participants' preferences between the items in a given pair frequently switched when the third item in the set was changed, but this tendency was reduced among individuals with ASC, which indicated that their choices were more consistent and conventionally rational than those of control participants...
June 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/28635314/fluorescent-labeled-bioconjugates-of-the-opioid-peptides-biphalin-and-dpdpe-incorporating-fluorescein-maleimide-linkers
#7
Azzurra Stefanucci, Wei Lei, Victor J Hruby, Giorgia Macedonio, Grazia Luisi, Simone Carradori, John M Streicher, Adriano Mollica
AIM: The conjugation of fluorescent labels to opioid peptides is an extremely challenging task, which needs to be overcome to create new classes of probes for biological assays. MATERIALS & METHODS: Three opioid peptide analogs of biphalin and [D-Pen2,5]-Enkephalin (DPDPE) containing a fluorescein-maleimide motif were synthesized. RESULTS & DISCUSSION: The biphalin analog 17 binds to opioid receptors with Ki(μ) = 530 ± 90 nM and Ki(δ) = 69...
June 2017: Future Medicinal Chemistry
https://www.readbyqxmd.com/read/28634459/cognitive-correlates-of-different-mentalizing-abilities-in-individuals-with-high-and-low-trait-schizotypy-findings-from-an-extreme-group-design
#8
Krisztina Kocsis-Bogár, Simone Kotulla, Susanne Maier, Martin Voracek, Kristina Hennig-Fast
Mentalizing or Theory of Mind (ToM) deficits in schizophrenia have been studied to great extent, but studies involving samples of trait schizotypy yield ambiguous results. Executive functions like cognitive inhibition, cognitive flexibility, and agency are all prerequisites of mentalizing, and it is assumed that the impairment of these functions contributes to ToM deficits in schizophrenia. Whether these impairments influence the ToM performance of people with high trait schizotypy remains unclear. Although impaired self-agency has repeatedly been identified in people with schizotypy, its role in mentalizing is yet to be investigated...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28632874/screening-for-obesity-in-children-and-adolescents-us-preventive-services-task-force-recommendation-statement
#9
David C Grossman, Kirsten Bibbins-Domingo, Susan J Curry, Michael J Barry, Karina W Davidson, Chyke A Doubeni, John W Epling, Alex R Kemper, Alex H Krist, Ann E Kurth, C Seth Landefeld, Carol M Mangione, Maureen G Phipps, Michael Silverstein, Melissa A Simon, Chien-Wen Tseng
Importance: Based on year 2000 Centers for Disease Control and Prevention growth charts, approximately 17% of children and adolescents aged 2 to 19 years in the United States have obesity, and almost 32% of children and adolescents are overweight or have obesity. Obesity in children and adolescents is associated with morbidity such as mental health and psychological issues, asthma, obstructive sleep apnea, orthopedic problems, and adverse cardiovascular and metabolic outcomes (eg, high blood pressure, abnormal lipid levels, and insulin resistance)...
June 20, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28630479/attention-cognitive-control-and-motivation-in-adhd-linking-event-related-brain-potentials-and-dna-methylation-patterns-in-boys-at-early-school-age
#10
Hartmut Heinrich, Juliane Grunitz, Valeska Stonawski, Stefan Frey, Simone Wahl, Björn Albrecht, Tamme W Goecke, Matthias W Beckmann, Johannes Kornhuber, Peter A Fasching, Gunther H Moll, Anna Eichler
In order to better understand the underpinnings of attention-deficit/hyperactivity disorder (ADHD), we targeted the relationship of attentional, cognitive control and motivational processes with DNA methylation patterns of 60 candidate genes in boys at early school age. Participants (6 to 8 years; N = 82) were selected from a German longitudinal cohort (FRANCES). ADHD-related behaviour was assessed via maternal ratings. Performance and event-related potential measures (inter alia Cue-P3 and Nogo-P3), which were recorded in a motivational go/nogo task, indicated diminished attentional orienting, reduced inhibitory response control and a larger motivational effect on performance in ADHD already at this relatively young age...
June 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28624991/a-new-global-and-comprehensive-model-for-icu-ventilator-performances-evaluation
#11
Nicolas S Marjanovic, Agathe De Simone, Guillaume Jegou, Erwan L'Her
BACKGROUND: This study aimed to provide a new global and comprehensive evaluation of recent ICU ventilators taking into account both technical performances and ergonomics. METHODS: Six recent ICU ventilators were evaluated. Technical performances were assessed under two FIO2 levels (100%, 50%), three respiratory mechanics combinations (Normal: compliance [C] = 70 mL cmH2O(-1)/resistance [R] = 5 cmH2O L(-1) s(-1); Restrictive: C = 30/R = 10; Obstructive: C = 120/R = 20), four exponential levels of leaks (from 0 to 12...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28611709/relationships-between-motor-and-executive-functions-and-the-effect-of-an-acute-coordinative-intervention-on-executive-functions-in-kindergartners
#12
Marion Stein, Max Auerswald, Mirjam Ebersbach
There is growing evidence indicating positive, causal effects of acute physical activity on cognitive performance of school children, adolescents, and adults. However, only a few studies examined these effects in kindergartners, even though correlational studies suggest moderate relationships between motor and cognitive functions in this age group. One aim of the present study was to examine the correlational relationships between motor and executive functions among 5- to 6-year-olds. Another aim was to test whether an acute coordinative intervention, which was adapted to the individual motor functions of the children, causally affected different executive functions (i...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28608273/how-long-lasting-is-the-post-conflict-slowing-after-incongruent-trials-evidence-from-the-stroop-simon-and-flanker-tasks
#13
Alodie Rey-Mermet, Beat Meier
The purpose of the present study was to determine how long-lasting the post-conflict slowing following incongruent stimuli is. In previous research, incongruent stimuli have been used to induce a conflict because they have relevant features for two different response alternatives. So far, the post-conflict slowing following incongruent stimuli has mainly been assessed up to one trial. In the first two experiments, we assessed the persistence of the post-conflict slowing across several trials. To this end, we presented a few incongruent stimuli among non-conflict stimuli...
June 12, 2017: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/28608004/effector-system-specific-sequential-modulations-of-congruency-effects
#14
Markus Janczyk, Hartmut Leuthold
Congruency effects in conflict tasks are reliably reduced after experiencing conflict, that is, following incongruent trials. Such sequential modulations (sometimes referred to as the Gratton effect) indicate the operation of conflict adaptation mechanisms. The influential conflict monitoring hypothesis suggested that after conflict the processing of relevant stimulus dimensions is increased. Alternatively, it was suggested that the influence of automatic response activation is suppressed following conflict...
June 12, 2017: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/28606783/methylprednisolone-as-a-memory-enhancer-in-rats-effects-on-aversive-memory-long-term-potentiation-and-calcium-influx
#15
Liane da Silva de Vargas, Rithiele Gonçalves, Marcus Vinícius S Lara, Zaquer S M Costa-Ferro, Simone Denise Salamoni, Michelle Flores Domingues, Angela Regina Piovesan, Dênis Reis de Assis, Lucia Vinade, Alexandre P Corrado, Wilson Alves-Do-Prado, Paulo Correia-de-Sá, Jaderson Costa da Costa, Ivan Izquierdo, Cháriston A Dal Belo, Pâmela B Mello-Carpes
It is well recognized that stress or glucocorticoids hormones treatment can modulate memory performance in both directions, either impairing or enhancing it. Despite the high number of studies aiming at explaining the effects of glucocorticoids on memory, this has not yet been completely elucidated. Here, we demonstrate that a low daily dose of methylprednisolone (MP, 5 mg/kg, i.p.) administered for 10-days favors aversive memory persistence in adult rats, without any effect on the exploring behavior, locomotor activity, anxiety levels and pain perception...
June 9, 2017: Brain Research
https://www.readbyqxmd.com/read/28604840/working-memory-operates-over-the-same-representations-as-attention
#16
Ke Chen, Yanyan Ye, Jiushu Xie, Tiansheng Xia, Lei Mo
A recent study observed a working memory (WM) Stroop effect with a magnitude equivalent to that of the classic Stroop effect, indicating that WM operates over the same representations as attention. However, more research is needed to examine this proposal. One unanswered question is whether the WM Stroop effect occurs when the WM item and the perceptual task do not have an overlapping response set. We addressed this question in Experiment 1 by conducting an attentional word-color task and a WM word-color task...
2017: PloS One
https://www.readbyqxmd.com/read/28601335/-take-home-box-trainers-are-an-effective-alternative-to-virtual-reality-simulators
#17
Marina Yiasemidou, Jonathan de Siqueira, James Tomlinson, Daniel Glassman, Simon Stock, Michael Gough
BACKGROUND: Practice on virtual reality simulators (VRSs) has been shown to improve surgical performance. However, VRSs are expensive and usually housed in surgical skills centers that may be inaccessible at times convenient for surgical trainees to practice. Conversely, box trainers (BT) are inexpensive and can be used anywhere at anytime. This study assesses "take-home" BTs as an alternative to VRS. METHODS: After baseline assessments (two simulated laparoscopic cholecystectomies, one on a VRS and one on a BT), 25 surgical trainees were randomized to two groups...
June 1, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28599833/the-effects-of-methylphenidate-on-the-neural-signatures-of-sustained-attention
#18
Paul M Dockree, Jessica J Barnes, Natasha Matthews, Angela J Dean, Rafael Abe, L Sanjay Nandam, Simon P Kelly, Mark A Bellgrove, Redmond G O'Connell
BACKGROUND: Although it is well established that methylphenidate (MPH) enhances sustained attention, the neural mechanisms underpinning this improvement remain unclear. We examined how MPH influenced known electrophysiological precursors of lapsing attention over different time scales. METHODS: We measured the impact of MPH, compared with placebo, on behavioral and electrocortical markers while healthy adults (n = 40) performed a continuous monitoring paradigm designed to elicit attentional lapses...
May 10, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/28597368/health-related-resource-use-measurement-instruments-for-intersectoral-costs-and-benefits-in-the-education-and-criminal-justice-sectors
#19
REVIEW
Susanne Mayer, Aggie T G Paulus, Agata Łaszewska, Judit Simon, Ruben M W A Drost, Dirk Ruwaard, Silvia M A A Evers
BACKGROUND: Intersectoral costs and benefits (ICBs), i.e. costs and benefits of healthcare interventions outside the healthcare sector, can be a crucial component in economic evaluations from the societal perspective. Pivotal to their estimation is the existence of sound resource-use measurement (RUM) instruments; however, RUM instruments for ICBs in the education or criminal justice sectors have not yet been systematically collated or their psychometric quality assessed. This review aims to fill this gap...
June 8, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28597322/sustained-attention-to-a-predictable-unengaging-go-no-go-task-shows-ongoing-development-between-6-and-11%C3%A2-years
#20
Frances C Lewis, Robert A Reeve, Simon P Kelly, Katherine A Johnson
Response time variability (RTV) is a useful measure of sustained attention; however, little is known about developmental changes in RTV at different temporal frequencies. Thirty-five 6-year-olds, 31 8-year-olds, and 37 10-year-olds completed the fixed-sequence Sustained Attention to Response Task on three occasions, six months apart. Fast Fourier Transform and ex-Gaussian analyses of response time (RT) data assessed momentary fluctuations in RT, gradual changes in RT, and very long responses, thought to reflect attentional control fluctuations, slow-shifting arousal, and infrequent lapses in attention, respectively...
June 8, 2017: Attention, Perception & Psychophysics
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