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https://www.readbyqxmd.com/read/28821209/cued-memory-reactivation-during-sws-abolishes-the-beneficial-effect-of-sleep-on-abstraction
#1
Nora Hennies, Matthew A Lambon Ralph, Simon J Durrant, James N Cousins, Penelope A Lewis
Study Objectives: Extracting regularities from stimuli in our environment and generalizing these to new situations are fundamental processes in human cognition. Sleep has been shown to enhance these processes, possibly by facilitating reactivation-triggered memory reorganization. Here, we assessed whether cued reactivation during slow wave sleep (SWS) promotes the beneficial effect of sleep on abstraction of statistical regularities. Methods: We used an auditory statistical learning task, in which the benefit of sleep has been firmly established...
August 1, 2017: Sleep
https://www.readbyqxmd.com/read/28820952/adult-intelligence-the-construct-and-the-criterion-problem
#2
Phillip L Ackerman
Over 100 years have passed since Binet and Simon proposed scales for assessment of intelligence of children to predict academic success and failure. The extension of these assessments to adults largely resulted from efforts of psychologists to provide insights for military selection in World War I. At the time, relatively little thought was given to how adult intelligence might differ from child and adolescent intelligence. Traditional approaches for assessing adult intelligence have largely survived. However, there is little reference to adult intellectual functioning outside of laboratory-based tasks and clinical assessments of pathology...
August 1, 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/28820427/a-review-of-the-neuropsychological-dimensions-of-tourette-syndrome
#3
REVIEW
Simon Morand-Beaulieu, Julie B Leclerc, Philippe Valois, Marc E Lavoie, Kieron P O'Connor, Bruno Gauthier
Neurocognitive functioning in Tourette syndrome (TS) has been the subject of intensive research in the past 30 years. A variety of impairments, presumably related to frontal and frontostriatal dysfunctions, have been observed. These impairments were found in various domains, such as attention, memory, executive functions, language, motor and visuomotor functions, among others. In line with contemporary research, other neurocognitive domains have recently been explored in TS, bringing evidence of altered social reasoning, for instance...
August 18, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28817417/brain-processing-of-the-temporal-dimension-of-acute-pain-in-short-term-memory
#4
Mina Khoshnejad, Mathieu Roy, Kristina Martinu, Jen-I Chen, Julien Cohen-Adad, Simon Grondin, Pierre Rainville
The dynamics of noxious sensation shapes pain perception, yet the memory of the temporal dimension of pain remains almost completely unexplored. Here, brain activity during the memory of pain duration was contrasted with that associated with the memory of pain intensity using functional magnetic resonance imaging (fMRI) and a delayed-reproduction task. Participants encoded, maintained during a short delay, and reproduced (1) the 'duration' of pain (i.e. onset-to-offset), (2) the 'dynamics' of pain (i.e. evolution of pain over time), or (3) the intensity of pain (i...
July 3, 2017: Pain
https://www.readbyqxmd.com/read/28816146/quality-assessment-of-stereotactic-radiosurgery-of-a-melanoma-brain-metastases-model-using-a-mouselike-phantom-and-the-small-animal-radiation-research-platform
#5
Cheng-Chia Wu, Kunal R Chaudhary, Yong Hum Na, David Welch, Paul J Black, Adam M Sonabend, Peter Canoll, Yvonne M Saenger, Tony J C Wang, Cheng-Shie Wuu, Tom K Hei, Simon K Cheng
PURPOSE: To establish a novel preclinical model for stereotactic radiosurgery (SRS) with combined mouselike phantom quality assurance in the setting of brain metastases. METHODS AND MATERIALS: C57B6 mice underwent intracranial injection of B16-F10 melanoma cells. T1-weighted postcontrast magnetic resonance imaging (MRI) was performed on day 11 after injection. The MRI images were fused with cone beam computed tomography (CBCT) images using the Small Animal Radiation Research Platform (SARRP)...
September 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28813992/review-of-the-actuators-of-active-knee-prostheses-and-their-target-design-outputs-for-activities-of-daily-living
#6
Dominik Simon Pieringer, Martin Grimmer, Michael Friedrich Russold, Robert Riener
Active prosthetic knees have the capability to provide net positive work, which is required in daily activities like stair and ramp negotiation or sit-to-stand transfers. Adding this capability might help to increase user mobility, safety, and independence. This article summarizes the biomechanical knee requirements for different activities of daily living and critically compares them with the actuator characteristics of state-of-the-art active prosthetic knee joints. As a result of a systematic literature research 22 active prosthetic knee joints were identified...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813958/quantitative-assessment-of-motor-functions-post-stroke-responsiveness-of-upper-extremity-robotic-measures-and-its-task-dependence
#7
Asif Hussain, Aamani Budhota, Sara Contu, Simone Kager, Deshmukh A Vishwanath, Christopher W K Kuah, Lester H L Yam, Karen S G Chua, Lorenzo Masia, Domenico Campolo
Technology aided measures offer a sensitive, accurate and time-efflcient approach for the assessment of sensorimotor function after neurological impairment compared to standard clinical assessments. This preliminary study investigated the relationship between task definition and its effect on robotic measures using a planar, two degree of freedom, robotic-manipulator (H-Man). Four chronic stroke participants (49.5±11.95 years, 2 Female, FMA: 37.5±13.96) and eight healthy control participants (26.25± 4.70 years, 2 Female) participated in the study...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813890/online-adaptive-assistance-control-in-robot-based-neurorehabilitation-therapy
#8
Fabio Stroppa, Simone Marcheschi, Nicola Mastronicola, Claudio Loconsole, Antonio Frisoli
Repetitive and task specific robot-based rehabilitation has been proved to be effective for motor recovery over time. During a therapy, the task should improve subject's impaired movements, but also enhance their efforts for a more effective recovery. This requires an accurate tuning of the task difficulty, which should be tailored directly to the patient. In this work, we propose a system for real-time assistance adaptation based on online performance evaluation for post-stroke subjects. In particular, the aim of the system is to implement the "assist-as-needed" paradigm based on actual patients' motor skills during a therapy session with an active upper-limb robotic exoskeleton...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28809700/cognitive-cost-of-using-augmented-reality-displays
#9
James Baumeister, Seung Youb Ssin, Neven A M ElSayed, Jillian Dorrian, David P Webb, James A Walsh, Timothy M Simon, Andrew Irlitti, Ross T Smith, Mark Kohler, Bruce H Thomas
This paper presents the results of two cognitive load studies comparing three augmented reality display technologies: spatial augmented reality, the optical see-through Microsoft HoloLens, and the video see-through Samsung Gear VR. In particular, the two experiments focused on isolating the cognitive load cost of receiving instructions for a button-pressing procedural task. The studies employed a self-assessment cognitive load methodology, as well as an additional dual-task cognitive load methodology. The results showed that spatial augmented reality led to increased performance and reduced cognitive load...
August 10, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28805475/menopausal-hormone-therapy-for-primary-prevention-why-the-uspstf-is-wrong
#10
R D Langer, J A Simon, A Pines, R A Lobo, H N Hodis, J H Pickar, D F Archer, P M Sarrel, W H Utian
The US Preventive Services Task Force (USPSTF) Draft Recommendation statement on Menopausal Hormone Therapy: Primary Prevention for Chronic Diseases, released in May 2017, perpetuates a major disconnect between the primary population affected, women within roughly 10 years of menopause, and the data cited. Furthermore, major elements of the evidence relied upon have been misinterpreted or misstated, particularly in regard to coronary heart disease and breast cancer, for which there is no statistically significant evidence of harm...
August 14, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28796622/w-fyd-a-wearable-fabric-based-display-for-haptic-multi-cue-delivery-and-tactile-augmented-reality
#11
Simone Fani, Simone Ciotti, Edoardo Battaglia, Alessandro Moscatelli, Matteo Bianchi
Despite the importance of softness, there is no evidence of wearable haptic systems able to deliver controllable softness cues. Here, we present the Wearable Fabric Yielding Display (W-FYD), a fabric-based display for multi-cue delivery that can be worn on user's finger and enables, for the first time, both active and passive softness exploration. It can also induce a sliding effect under the finger-pad. A given stiffness profile can be obtained by modulating the stretching state of the fabric through two motors...
August 7, 2017: IEEE Transactions on Haptics
https://www.readbyqxmd.com/read/28795222/whose-turn-is-it-anyway-the-moderating-role-of-response-execution-certainty-on-the-joint-simon-effect
#12
April Karlinsky, Melanie Y Lam, Romeo Chua, Nicola J Hodges
When a two-choice "Simon task" is distributed between two people, performance in the shared go/no-go task resembles performance in the whole task alone. This finding has been described as the joint Simon effect (JSE). Unlike the individual go/no-go task, not only is the typical joint Simon task shared with another person, but also the imperative stimuli dictate whose turn it is to respond. Therefore, in the current study, we asked whether removing the agent discrimination component of the joint Simon task influences co-representation...
August 9, 2017: Psychological Research
https://www.readbyqxmd.com/read/28789659/consistency-and-sources-of-divergence-in-recommendations-on-screening-with-questionnaires-for-presently-experienced-health-problems-or-symptoms-a-comparison-of-recommendations-from-the-canadian-task-force-on-preventive-health-care-uk-national-screening-committee
#13
Brett D Thombs, Nazanin Saadat, Kira E Riehm, Justin Michael Karter, Akansha Vaswani, Bonnie K Andrews, Peter Simons, Lisa Cosgrove
BACKGROUND: Recently, health screening recommendations have gone beyond screening for early-stage, asymptomatic disease to include "screening" for presently experienced health problems and symptoms using self-report questionnaires. We examined recommendations from three major national guideline organizations to determine the consistency of recommendations, identify sources of divergent recommendations, and determine if guideline organizations have identified any direct randomized controlled trial (RCT) evidence for the effectiveness of questionnaire-based screening...
August 9, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28777748/fully-automatic-mri-based-hippocampus-volumetry-using-fsl-first-intra-scanner-test-retest-stability-inter-field-strength-variability-and-performance-as-enrichment-biomarker-for-clinical-trials-using-prodromal-target-populations-at-risk-for-alzheimer-s-disease
#14
Enrica Cavedo, Per Suppa, Catharina Lange, Roland Opfer, Simone Lista, Samantha Galluzzi, Adam J Schwarz, Lothar Spies, Ralph Buchert, Harald Hampel
BACKGROUND: MRI-based hippocampus volume is a core clinical biomarker for identification of Alzheimer's disease (AD). OBJECTIVE: To assess robustness of automatic hippocampus volumetry with the freely available FSL-FIRST software with respect to short-term repeat and across field strength imaging. FSL-FIRST hippocampus volume (FIRST-HV) was also evaluated as enrichment biomarker for mild cognitive impairment (MCI) trials. METHODS: Robustness of FIRST-HV was assessed in 51 healthy controls (HC), 74 MCI subjects, and 28 patients with AD dementia from ADNI1, each with two pairs of back-to-back scans, one at 1...
July 29, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28776486/effects-of-age-on-inhibitory-control-are-affected-by-task-specific-features
#15
Angela de Bruin, Sergio Della Sala
Older adults have been argued to have impoverished inhibitory control compared to younger adults. However, these effects of age may depend on processing speed and their manifestation may furthermore depend on the type of inhibitory control task that is used. We present two experiments that examine age effects on inhibition across three tasks: a Simon arrow, static flanker, and motion flanker task. The results showed overall slower RTs for older adults on all three tasks. However, effects of age on inhibition costs were only found for the Simon task, but not for the two flanker tasks...
August 4, 2017: Quarterly Journal of Experimental Psychology: QJEP
https://www.readbyqxmd.com/read/28776213/-standards-for-treatment-in-forensic-committment-according-to-%C3%A2-%C3%A2-63-and-%C3%A2-%C3%A2-64-of-the-german-criminal-code-interdisciplinary-task-force-of-the-dgppn
#16
REVIEW
J L Müller, N Saimeh, P Briken, S Eucker, K Hoffmann, M Koller, T Wolf, M Dudeck, C Hartl, A-K Jakovljevic, V Klein, G Knecht, R Müller-Isberner, J Muysers, K Schiltz, D Seifert, A Simon, H Steinböck, W Stuckmann, W Weissbeck, C Wiesemann, R Zeidler
People who have been convicted of a crime due to a severe mental disorder and continue to be dangerous as a result of this disorder may be placed in a forensic psychiatric facility for improvement and safeguarding according to § 63 and § 64 of the German Criminal Code (StGB). In Germany, approximately 9000 patients are treated in clinics for forensic psychiatry and psychotherapy on the basis of § 63 of the StGB and in withdrawal centers on the basis of § 64 StGB. The laws for treatment of patients in forensic commitment are passed by the individual States, with the result that even the basic conditions differ in the individual States...
August 3, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28771763/farmarel-an-italian-pharmacovigilance-project-to-monitor-and-evaluate-adverse-drug-reactions-in-haematologic-patients
#17
Nicola S Fracchiolla, Silvia Artuso, Agostino Cortelezzi, Anna M Pelizzari, Paola Tozzi, Maurizio Bonfichi, Federica Bocchio, Livio Gargantini, Elisa De Rosa, Giuseppe D Vighi, Lucia Prestini, Simona Sammassimo, Niccolò Frungillo, Maria C Pasquini, Alessandra Ragazzi, Daniele Boghi, Alessia Pastore, Eraldo Lanzi, Giuseppe Gritti, Giulia Quaresmini, Simone Voltolini, Roberta Gaiardoni, Consuelo Corti, Maria C Vilardo, Maria L La Targia, Giacomo Berini, Massimo Magagnoli, Claudia Bacci, Dario Consonni, Alma L Rivolta, Giuliana Muti
Adverse drug reactions (ADRs) reduce patients' quality of life, increase mortality and morbidity, and have a negative economic impact on healthcare systems. Nevertheless, the importance of ADR reporting is often underestimated. The project "FarmaREL" has been developed to monitor and evaluate ADRs in haematological patients and to increase pharmacovigilance culture among haematology specialists. In 13 haematology units, based in Lombardy, Italy, a dedicated specialist with the task of encouraging ADRs reporting and sensitizing healthcare professionals to pharmacovigilance has been assigned...
August 3, 2017: Hematological Oncology
https://www.readbyqxmd.com/read/28769773/finding-home-landmark-ambiguity-in-human-navigation
#18
Simon Jetzschke, Marc O Ernst, Julia Froehlich, Norbert Boeddeker
Memories of places often include landmark cues, i.e., information provided by the spatial arrangement of distinct objects with respect to the target location. To study how humans combine landmark information for navigation, we conducted two experiments: To this end, participants were either provided with auditory landmarks while walking in a large sports hall or with visual landmarks while walking on a virtual-reality treadmill setup. We found that participants cannot reliably locate their home position due to ambiguities in the spatial arrangement when only one or two uniform landmarks provide cues with respect to the target...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28768906/integration-of-homeostatic-signaling-and-food-reward-processing-in-the-human-brain
#19
Joe J Simon, Anne Wetzel, Maria Hamze Sinno, Mandy Skunde, Martin Bendszus, Hubert Preissl, Paul Enck, Wolfgang Herzog, Hans-Christoph Friederich
BACKGROUND: Food intake is guided by homeostatic needs and by the reward value of food, yet the exact relation between the two remains unclear. The aim of this study was to investigate the influence of different metabolic states and hormonal satiety signaling on responses in neural reward networks. METHODS: Twenty-three healthy participants underwent functional magnetic resonance imaging while performing a task distinguishing between the anticipation and the receipt of either food- or monetary-related reward...
August 3, 2017: JCI Insight
https://www.readbyqxmd.com/read/28744891/qualitative-research-using-realist-evaluation-to-explain-preparedness-for-doctors-memorable-firsts
#20
Janet Lefroy, Sarah Yardley, Ruth Kinston, Simon Gay, Stuart McBain, Robert McKinley
CONTEXT: Doctors must be competent from their first day of practice if patients are to be safe. Medical students and new doctors are acutely aware of this, but describe being variably prepared. OBJECTIVES: This study aimed to identify causal chains of the contextual factors and mechanisms that lead to a trainee being capable (or not) of completing tasks for the first time. METHODS: We studied three stages of transition: anticipation; lived experience, and post hoc reflection...
July 26, 2017: Medical Education
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