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Royal jelli

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https://www.readbyqxmd.com/read/28178217/flavonoid-composition-and-antitumor-activity-of-bee-bread-collected-in-northeast-portugal
#1
Filipa Sobral, Ricardo C Calhelha, Lillian Barros, Montserrat Dueñas, Andreia Tomás, Celestino Santos-Buelga, Miguel Vilas-Boas, Isabel C F R Ferreira
Bee bread (BB) is a fermented mixture of plant pollen, honey, and bee saliva that worker bees use as food for larvae, and for young bees to produce royal jelly. In the present study, five BB samples, collected from Apis mellifera iberiensis hives located in different apiaries near Bragança, in the northeast region of Portugal, and one BB commercial sample were characterized by high-performance liquid chromatography coupled to a diode array detector and electrospray mass spectrometry (HPLC-DAD-ESI/MS) in terms of phenolic compounds, such as flavonoid glycoside derivatives...
February 7, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28170034/comparative-analyses-of-the-major-royal-jelly-protein-gene-cluster-in-three-apis-species-with-long-amplicon-sequencing
#2
Sophie Helbing, H Michael G Lattorff, Robin F A Moritz, Anja Buttstedt
No abstract text is available yet for this article.
February 7, 2017: DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes
https://www.readbyqxmd.com/read/28089395/royal-jelly-ameliorates-diet-induced-obesity-and-glucose-intolerance-by-promoting-brown-adipose-tissue-thermogenesis-in-mice
#3
Takeshi Yoneshiro, Ryuji Kaede, Kazuki Nagaya, Julia Aoyama, Mana Saito, Yuko Okamatsu-Ogura, Kazuhiro Kimura, Akira Terao
INTRODUCTION: Identification of thermogenic food ingredients is potentially a useful strategy for the prevention of obesity and related metabolic disorders. It has been reported that royal jelly (RJ) supplementation improves insulin sensitivity; however, its impacts on energy expenditure and adiposity remain elusive. We investigated anti-obesity effects of RJ supplementation and their relation to physical activity levels and thermogenic capacities of brown (BAT) and white adipose tissue (WAT)...
January 11, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28070251/comparison-between-vaginal-royal-jelly-and-vaginal-estrogen-effects-on-quality-of-life-and-vaginal-atrophy-in-postmenopausal-women-a-clinical-trial-study
#4
Fatemeh Seyyedi, Mahmoud Rafiean Kopaei, Sepideh Miraj
OBJECTIVE: This study was conducted to evaluate the therapeutic effects of vaginal royal jelly and vaginal estrogen on quality of life and vaginal atrophy in postmenopausal women. METHODS: This double-blind randomized controlled clinical trial was carried out at gynecology and obstetrics clinics of Hajar Hospital of Shahrekord University of Medical Sciences (Iran) from January 2013 to January 2014. The study was conducted on married postmenopausal women between 50 and 65 years old...
November 2016: Electronic Physician
https://www.readbyqxmd.com/read/28060936/clinical-evaluation-of-a-royal-jelly-supplementation-for-the-restoration-of-dry-eye-a-prospective-randomized-double-blind-placebo-controlled-study-and-an-experimental-mouse-model
#5
Sachiko Inoue, Motoko Kawashima, Ryuji Hisamura, Toshihiro Imada, Yusuke Izuta, Shigeru Nakamura, Masataka Ito, Kazuo Tsubota
BACKGROUND: Dry eye is a multifactorial disease characterized by ocular discomfort and visual impairment. Lacrimal gland function has been shown to decrease with aging, a known potent risk factor for dry eye. We have previously found that orally administrated royal jelly (RJ) restored tear secretion in a rat model of dry eye. METHODS AND FINDINGS: We examined the effects of RJ oral administration on dry eye in this prospective, randomized, double-blind, placebo-controlled study...
2017: PloS One
https://www.readbyqxmd.com/read/27979092/development-and-validation-of-a-multiclass-method-for-the-quantification-of-veterinary-drug-residues-in-honey-and-royal-jelly-by-liquid-chromatography-tandem-mass-spectrometry
#6
Yue Jin, Jinzhen Zhang, Wen Zhao, Wenwen Zhang, Lin Wang, Jinhui Zhou, Yi Li
The aim of this study was to develop an analytical method for the analysis of a wide range of veterinary drugs in honey and royal jelly. A modified sample preparation procedure based on the quick, easy, cheap, effective, rugged and safe (QuEChERS) method was developed, followed by liquid chromatography tandem mass spectrometry determination. Use of the single sample preparation method for analysis of 42 veterinary drugs becomes more valuable because honey and royal jelly belong to completely different complex matrices...
April 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27937077/hypocholesterolemic-efficacy-of-royal-jelly-in-healthy-mild-hypercholesterolemic-adults
#7
Hui-Fang Chiu, Bo-Kai Chen, Yan-Ying Lu, Yi-Chun Han, You-Cheng Shen, Kamesh Venkatakrishnan, Oksana Golovinskaia, Chin-Kun Wang
CONTEXT: Royal jelly (RJ) has been reported for its health promoting factors such as antioxidant, anti-inflammatory and lipid lowering activities. OBJECTIVE: The present randomized, placebo-controlled study examines the hypolipidemic beneficial effect of RJ through evaluating anthropometric measurements, lipid profile and various hormone levels in mildly hypercholesterolemic participants. MATERIALS AND METHODS: Forty subjects with mild hypercholesterolemia (180-200 mg/dL) were randomly selected and divided into two groups as experimental or placebo, who requested to intake nine capsules (350 mg/capsule) of RJ or placebo/day, respectively, for three months with one month of follow-up without any supplementation...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/27908685/royal-jelly-supplemented-soybean-lecithin-based-extenders-improve-post-thaw-quality-and-incubation-resilience-of-goat-spermatozoa
#8
Selim Alcay, M Berk Toker, N Tekin Onder, Elif Gokce
The aim of the present study was to evaluate different concentrations of royal jelly (RJ) supplemented extenders for post-thaw quality and incubation resilience of goat spermatozoa. Semen samples were collected from five goats. Pooled semen were diluted with soybean lecithin-based extender without RJ (control) or supplemented with different concentrations (0.25, 0.5 and 0.75%) of RJ (RJ0.25, RJ0.5, RJ0.75 respectively), at a final concentration of 150 × 10(6) spermatozoon/mL. Semen samples were assessed for sperm motility, plasma membrane integrity using hypoosmotic swelling test (HOST) damaged acrosome using FITC-Pisum sativum agglutinin (PSA-FITC) and DNA integrity using terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL)...
November 28, 2016: Cryobiology
https://www.readbyqxmd.com/read/27901009/occupational-asthma-caused-by-inhalable-royal-jelly-and-its-cross-reactivity-with-honeybee-venom
#9
Li-Sha Li, Kai Guan
No abstract text is available yet for this article.
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27890887/royal-jelly-improves-hyperglycemia-in-obese-diabetic-kk-ay-mice
#10
Mei Yoshida, Kaori Hayashi, Risa Watadani, Yoshiyasu Okano, Keiya Tanimura, Jun Kotoh, Daiki Sasaki, Kozo Matsumoto, Akihiko Maeda
The study examined whether royal jelly (RJ) can prevent obesity and ameliorate hyperglycemia in type 2 diabetes. This study utilized obese/diabetic KK-Ay mice. RJ (10 mg/kg) was administered by oral gavage. Body weight, plasma glucose and insulin levels were measured. mRNA and protein levels were determined using quantitative reverse transcription polymerase chain reaction and western blotting, respectively. Four weeks of RJ administration improved hyperglycemia and partially suppressed body weight gain, although the latter effect did not reach statistical significance...
November 26, 2016: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/27887663/effects-of-royal-jelly-supplementation-on-regulatory-t-cells-in-children-with-sle
#11
Asmaa M Zahran, Khalid I Elsayh, Khaled Saad, Esraa M A Eloseily, Naglaa S Osman, Mohamd A Alblihed, Gamal Badr, Mohamed H Mahmoud
BACKGROUND AND OBJECTIVE: To our knowledge, no previous studies have focused on the immunomodulatory effects of fresh royal jelly (RJ) administration on systemic lupus erythematosus (SLE) in humans. Our aim was to study the effect of fresh RJ administration on the disease course in children with SLE with some immunological markers (CD4(+) and CD8(+) regulatory T cells and T lymphocytes apoptosis). METHODS: This was an open-label study in which 20 SLE children received 2 g of freshly prepared RJ daily, for 12 weeks...
2016: Food & Nutrition Research
https://www.readbyqxmd.com/read/27865886/social-regulation-of-ageing-by-young-workers-in-the-honey-bee-apis-mellifera
#12
Michael Eyer, Benjamin Dainat, Peter Neumann, Vincent Dietemann
Organisms' lifespans are modulated by both genetic and environmental factors. The lifespan of eusocial insects is determined by features of the division of labor, which itself is influenced by social regulatory mechanisms. In the honey bee, Apis mellifera, the presence of brood and of old workers carrying out foraging tasks are important social drivers of ageing, but the influence of young adult workers is unknown, as it has not been experimentally teased apart from that of brood. In this study, we test the role of young workers in the ageing of their nestmates...
January 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/27847405/in-vitro-anti-inflammatory-effects-of-three-fatty-acids-from-royal-jelly
#13
Yi-Fan Chen, Kai Wang, Yan-Zheng Zhang, Yu-Fei Zheng, Fu-Liang Hu
Trans-10-hydroxy-2-decenoic acid (10-H2DA), 10-hydroxydecanoic acid (10-HDAA), and sebacic acid (SEA) are the three major fatty acids in royal jelly (RJ). Previous studies have revealed several pharmacological activities of 10-H2DA and 10-HDAA, although the anti-inflammatory effects and underlying mechanisms by which SEA acts are poorly understood. In the present study, we evaluated and compared the in vitro anti-inflammatory effects of these RJ fatty acids in lipopolysaccharide-stimulated RAW 264.7 macrophages...
2016: Mediators of Inflammation
https://www.readbyqxmd.com/read/27743422/food-to-some-poison-to-others-honeybee-royal-jelly-and-its-growth-inhibiting-effect-on-european-foulbrood-bacteria
#14
Thomas V Vezeteu, Otilia Bobiş, Robin F A Moritz, Anja Buttstedt
Honeybee colonies (Apis mellifera) serve as attractive hosts for a variety of pathogens providing optimal temperatures, humidity, and an abundance of food. Thus, honeybees have to deal with pathogens throughout their lives and, even as larvae they are affected by severe brood diseases like the European Foulbrood caused by Melissococcus plutonius. Accordingly, it is highly adaptive that larval food jelly contains antibiotic compounds. However, although food jelly is primarily consumed by bee larvae, studies investigating the antibiotic effects of this jelly have largely concentrated on bacterial human diseases...
February 2017: MicrobiologyOpen
https://www.readbyqxmd.com/read/27736245/improvement-of-neurological-disorders-in-postmenopausal-model-rats-by-administration-of-royal-jelly
#15
A Minami, H Matsushita, D Ieno, Y Matsuda, Y Horii, A Ishii, T Takahashi, H Kanazawa, A Wakatsuki, T Suzuki
OBJECTIVE: Royal jelly (RJ) from honeybees (Apis mellifera) has estrogenic activity. Estrogen deficiency after menopause leads to a high risk of memory impairment and depression as well as metabolic syndrome and osteoporosis. We here investigated the effect of RJ on memory impairment and depression-like behaviors in ovariectomized (OVX) rats. METHODS: OVX rats were administered with RJ for 82 days. Hippocampus-dependent spatial memory and depression-like behaviors were assessed by the Morris water maze test and the forced swimming test, respectively...
December 2016: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/27721892/quantitative-analysis-of-apisin-a-major-protein-unique-to-royal-jelly
#16
Takako Furusawa, Yasuko Arai, Kenji Kato, Kenji Ichihara
Apisin, a protein that is unique to royal jelly (RJ), is known to compose the greater part of the RJ proteins and to exist as a heterooligomer containing major royal jelly protein 1 and apisimin. However, few reports on the methods for quantifying apisin have been published. Thus, we attempted to quantify apisin using HPLC, a widely used analytical technique, as described below. Isoelectric precipitation and size-exclusion chromatography were used to obtain the purified protein, which was identified as apisin by SDS-PAGE and LC-MS analyses...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27715425/production-of-knockout-mutants-by-crispr-cas9-in-the-european-honeybee-apis-mellifera-l
#17
Hiroki Kohno, Shota Suenami, Hideaki Takeuchi, Tetsuhiko Sasaki, Takeo Kubo
The European honeybee (Apis mellifera L.) is used as a model organism in studies of the molecular and neural mechanisms underlying social behaviors and/or advanced brain functions. The entire honeybee genome has been sequenced, which has further advanced molecular biologic studies of the honeybee. Functions of genes of interest, however, remain largely to be elucidated in the honeybee due to the lack of effective reverse genetic methods. Moreover, genetically modified honeybees must be maintained under restricted laboratory conditions due to legal restrictions, further complicating the application of reverse genetics to this species...
October 2016: Zoological Science
https://www.readbyqxmd.com/read/27684286/preparation-of-single-cohort-colonies-and-hormone-treatment-of-worker-honeybees-to-analyze-physiology-associated-with-role-and-or-endocrine-system
#18
Takayuki Ueno, Kiyoshi Kawasaki, Takeo Kubo
Honeybee workers are engaged in various tasks related to maintaining colony activity. The tasks of the workers change according to their age (age-related division of labor). Young workers are engaged in nursing the brood (nurse bees), while older workers are engaged in foraging for nectar and pollen (foragers). The physiology of the workers changes in association with this role shift. For example, the main function of the hypopharyngeal glands (HPGs) changes from the secretion of major royal jelly proteins (MRJPs) to the secretion of carbohydrate-metabolizing enzymes...
2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27679827/antioxidant-and-protective-effects-of-royal-jelly-on-histopathological-changes-in-testis-of-diabetic-rats
#19
Elham Ghanbari, Vahid Nejati, Mozafar Khazaei
BACKGROUND: Diabetes is the most common endocrine disease. It has adverse effects on male reproductive function. Royal Jelly (RJ) has antioxidant and anti-diabetic effects and show protective effects against diabetes. OBJECTIVE: This study was conducted to evaluate the effect of RJ on histopathological alterations of the testicular tissue in streptozotocin (STZ)-induced diabetic rats. MATERIALS AND METHODS: In this experimental study, 28 adult Wistar rats were randomly divided into control (C), royal jelly (R), diabetic (D) and RJ-treated diabetic (D+R) groups...
August 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27664731/royal-jelly-an-ancient-remedy-with-remarkable-antibacterial-properties
#20
REVIEW
Filippo Fratini, Giovanni Cilia, Simone Mancini, Antonio Felicioli
Royal Jelly (RJ), a honeybee hypopharyngeal gland secretion of young nurse and an exclusive nourishment for bee queen, has been used since ancient times for care and human health and it is still very important in traditional and folkloristic medicine, especially in Asia within the apitherapy. Recently, RJ and its protein and lipid components have been subjected to several investigations on their antimicrobial activity due to extensive traditional uses and for a future application in medicine. Antimicrobial activities of crude Royal Jelly, Royalisin, 10-hydroxy-2-decenoic acid, Jelleines, Major Royal Jelly Proteins against different bacteria have been reported...
November 2016: Microbiological Research
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