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Royal jelli

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https://www.readbyqxmd.com/read/29344209/the-effect-of-royal-jelly-on-the-growth-of-breast-cancer-in-mice
#1
Shuang Zhang, Qiqi Shao, Haiyang Geng, Songkun Su
Due to various pharmacological properties, including antioxidative, anti-inflammatory and antibiotic properties, royal jelly (RJ) has been widely consumed in daily diets in numerous countries. In the present study, the effect of RJ on 4T1-bearing mice was investigated. The study was performed by feeding 4T1-bearing mice with RJ using either the prophylactic-therapeutic (PTRJ) or therapeutic (TRJ) method. The experimental results for the PTRJ group demonstrated that the weight of tumor was significantly reduced (RJ 0...
December 2017: Oncology Letters
https://www.readbyqxmd.com/read/29337139/identification-of-yellow-gene-family-in-agrotis-ipsilon-and-functional-analysis-of-aiyellow-y-by-crispr-cas9
#2
Xi'en Chen, Yanghui Cao, Shuai Zhan, Yong Zhang, Anjiang Tan, Yongping Huang
The yellow gene family has been identified in several model insects, but yellow genes were poorly identified in non-model insects and the functions of yellow genes are largely unknown. In this study, we identified seven yellow genes in an important agricultural pest Agrotis ipsilon. Each gene encodes a protein containing a major royal jelly domain. Phylogenetic analysis defined these genes as yellow-y, -b, -b2, -c, -d, -e, and -h, respectively. The A. ipsilon yellow genes yellow-b, -b2, and -c were stably expressed in all developmental stages and tissues analyzed, whereas the other four yellow genes had unique expression patterns, suggesting distinct physiological roles of each gene...
January 11, 2018: Insect Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29295499/long-term-administration-of-queen-bee-acid-qba-to-rodents-reduces-anxiety-like-behavior-promotes-neuronal-health-and-improves-body-composition
#3
Michael J Weiser, Vivian Grimshaw, Kelly M Wynalda, M Hasan Mohajeri, Christopher M Butt
BACKGROUND: Queen bee acid (QBA; 10-hydroxy-2-decenoic acid) is the predominant fatty acid in royal jelly (RJ) and has activity at estrogen receptors, which affect brain function and body composition. However, few, long-term studies have assessed QBA effects in brain health and body composition. METHODS: Primary hippocampal neurons were treated with QBA (0-30 µM) and challenged with glutamate or hypoxia. QBA was fed to aged, male Sprague-Dawley rats (12-24 mg/kg/day) and to adult male and female Balb/C mice (30-60 mg/kg/day) for ≥3...
December 23, 2017: Nutrients
https://www.readbyqxmd.com/read/29247927/comparison-of-salting-out-and-sugaring-out-liquid-liquid-extraction-methods-for-the-partition-of-10-hydroxy-2-decenoic-acid-in-royal-jelly-and-their-co-extracted-protein-content
#4
Xijuan Tu, Fanyi Sun, Siyuan Wu, Weiyi Liu, Zhaosheng Gao, Shaokang Huang, Wenbin Chen
Homogeneous liquid-liquid extraction (h-LLE) has been receiving considerable attention as a sample preparation method due to its simple and fast partition of compounds with a wide range of polarities. To better understand the differences between the two h-LLE extraction approaches, salting-out assisted liquid-liquid extraction (SALLE) and sugaring-out assisted liquid-liquid extraction (SULLE), have been compared for the partition of 10-hydroxy-2-decenoic acid (10-HDA) from royal jelly, and for the co-extraction of proteins...
January 15, 2018: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29198446/targeted-profiling-of-hydrophilic-constituents-of-royal-jelly-by-hydrophilic-interaction-liquid-chromatography-tandem-mass-spectrometry
#5
Athanasia Pina, Olga Begou, Dimitris Kanelis, Helen Gika, Stavros Kalogiannis, Chrysoula Tananaki, Georgios Theodoridis, Anastasia Zotou
In the present work a Hydrophilic Interaction Liquid Chromatography-tandem Mass Spectrometry (HILIC-MS/MS) method was developed for the efficient separation and quantification of a large number of small polar bioactive molecules in Royal Jelly. The method was validated and provided satisfactory detection sensitivity for 88 components. Quantification was proven to be precise for 64 components exhibiting good linearity, recoveries R% >90% for the majority of analytes and intra- and inter-day precision from 0...
November 13, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29197474/venomics-reveals-novel-ion-transport-peptide-likes-itpls-from-the-parasitoid-wasp-tetrastichus-brontispae
#6
Nai-Yong Liu, Zhi-Wen Xu, Wei Yan, Xue-Min Ren, Zhi-Quan Zhang, Jia-Ying Zhu
Despite substantial advances in uncovering constituents of parasitoid venoms due to their potential applications as insecticides and pharmaceuticals, most of these studies are primarily restricted to braconid and ichneumonid wasps. Little information is available regarding virulent factors from venom of Eulophidae. In order to provide insight into the venom components of this family and parasitoid venom evolution, a venom protein repertoire (venomics) of the endoparasitoid wasp, Tetrastichus brontispae was deciphered using a proteomic approach...
November 29, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29172539/proteome-comparisons-between-hemolymph-of-two-honeybee-strains-apis-mellifera-ligustica-reveal-divergent-molecular-basis-in-driving-hemolymph-function-and-high-royal-jelly-secretion
#7
Zewdu Ararso, Chuan Ma, Yuping Qi, Mao Feng, Bin Han, Han Hu, Lifeng Meng, Jianke Li
Hemolymph is vital for the immunity of honeybees, and offers a way to investigate their physiological status. To gain novel insight into the functionality and molecular details of the hemolymph in driving increased Royal Jelly (RJ) production, we characterized and compared hemolymph proteomes across the larval and adult ages of Italian bees (ITbs) and Royal Jelly bees (RJbs), a stock selected from ITbs for increasing RJ output. Unprecedented in-depth proteome was attained with the identification of 3394 hemolymph proteins in both bee lines...
November 27, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/29164636/development-and-validation-of-a-simple-solid-phase-extraction-method-coupled-with-liquid-chromatography-triple-quadrupole-tandem-mass-spectrometry-for-simultaneous-determination-of-lincomycin-tylosin-a-and-tylosin-b-in-royal-jelly
#8
Weijia Zheng, Jin-A Park, A M Abd El-Aty, Seong-Kwan Kim, Sang-Hyun Cho, Jeong-Min Choi, Mohamad Warda, Jing Wang, Jae-Han Shim, Ho-Chul Shin
We develop an analytical method for the determination of lincomycin, tylosin A, and tylosin B residues in royal jelly using liquid chromatography-triple quadrupole tandem mass spectrometry analysis. For extraction and purification, we employ 1% trifluoroacetic acid and 0.1 M Na2 EDTA solutions along with an Oasis HLB cartridge. The target antibiotics were well separated in a Kinetex EVO C18 reversed-phase analytical column using a combination of 0.1% formate acid in ultrapure water (A) and acetonitrile (B) as the mobile phase...
November 22, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/29136552/development-and-validation-of-modified-quechers-method-coupled-with-lc-ms-ms-for-simultaneous-determination-of-cymiazole-fipronil-coumaphos-fluvalinate-amitraz-and-its-metabolite-in-various-types-of-honey-and-royal-jelly
#9
Weijia Zheng, Jin-A Park, A M Abd El-Aty, Seong-Kwan Kim, Sang-Hyun Cho, Jeong-Min Choi, Hee Yi, Soo-Min Cho, Amer Ramadan, Ji Hoon Jeong, Jae-Han Shim, Ho-Chul Shin
Over the past few decades, honey products have been polluted by different contaminants, such as pesticides, which are widely applied in agriculture. In this work, a modified EN - quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction method was developed for the simultaneous quantification of pesticide residues, including cymiazole, fipronil, coumaphos, fluvalinate, amitraz, and its metabolite 2,4-dimethylaniline (2,4-DMA), in four types of honey (acacia, wild, chestnut, and manuka) and royal jelly...
November 8, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29123242/field-relevant-doses-of-the-systemic-insecticide-fipronil-and-fungicide-pyraclostrobin-impair-mandibular-and-hypopharyngeal-glands-in-nurse-honeybees-apis-mellifera
#10
Rodrigo Zaluski, Luis Antonio Justulin, Ricardo de Oliveira Orsi
Global decreases in bee populations emphasize the importance of assessing how environmental stressors affect colony maintenance, especially considering the extreme task specialization observed in honeybee societies. Royal jelly, a protein secretion essential to colony nutrition, is produced by nurse honeybees, and development of bee mandibular glands, which comprise a reservoir surrounded by secretory cells and hypopharyngeal glands that are shaped by acini, is directly associated with production of this secretion...
November 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29075644/royal-jelly-inhibits-pseudomonas-aeruginosa-adherence-and-reduces-excessive-inflammatory-responses-in-human-epithelial-cells
#11
Heni Susilowati, Keiji Murakami, Hiromichi Yumoto, Takashi Amoh, Kouji Hirao, Katsuhiko Hirota, Takashi Matsuo, Yoichiro Miyake
Pseudomonas aeruginosa is a Gram-negative bacterium and causes respiratory infection especially in elderly patients. Royal jelly has been used worldwide as a traditional remedy and as a nutrient; however, the effect against P. aeruginosa is unclear. The aim of this study was to analyze antibacterial, antiadherent, and anti-inflammatory effects of royal jelly against P. aeruginosa. Wild-type strain PAO1 and clinical isolates of P. aeruginosa were used for antibacterial assay and antiadherent assay to abiotic surface and epithelial cells, which are pharynx (Detroit 562) and lung (NCI-H292) epithelial cells...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29057141/transfer-and-metabolism-of-triadimefon-residues-from-rape-flowers-to-apicultural-products
#12
Ying-Hong Li, Bei-Lei Zhou, Ming-Rong Qian, Qiang Wang, Hu Zhang
This paper presents a study on the transfer and metabolism of triadimefon residues from rape flowers to apicultural products. In the field trials, honeybee colonies were placed in four rape greenhouses treated with triadimefon on standard dosage. Apicultural products (pollen, honey, and royal jelly) were collected on a regular basis. Sample preparation and extraction procedure were established. HPLC/ESI-MS/MS method was validated. The respective residues of triadimefon and metabolite triadimenol were 0.03 ± 0...
2017: Journal of Analytical Methods in Chemistry
https://www.readbyqxmd.com/read/29043701/royal-jelly-promotes-ovarian-follicles-growth-and-increases-steroid-hormones-in-immature-rats
#13
Elham Ghanbari, Mohammad Rasool Khazaei, Mozafar Khazaei, Vahid Nejati
Background: Royal jelly (RJ) is a complementary diet widely prescribed by traditional medicine specialists for treatment of infertility. The aim of present study was to evaluate the effects of RJ on a set of reproductive parameters in immature female rats. MATERIALS AND METHODS: In this experimental study, thirty two immature female rats (30-35 g) were divided into four groups (n=8/group): three experimental groups and one control. The experimental groups received 100, 200 and 400 mg/kg/body weight doses of RJ daily for 14 days, and the control group received 0...
January 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29029590/nutritional-physiology-and-ecology-of-honey-bees
#14
Geraldine A Wright, Susan W Nicolson, Sharoni Shafir
Honey bees feed on floral nectar and pollen that they store in their colonies as honey and bee bread. Social division of labor enables the collection of stores of food that are consumed by within-hive bees that convert stored pollen and honey into royal jelly. Royal jelly and other glandular secretions are the primary food of growing larvae and of the queen but are also fed to other colony members. Research clearly shows that bees regulate their intake, like other animals, around specific proportions of macronutrients...
October 13, 2017: Annual Review of Entomology
https://www.readbyqxmd.com/read/29028361/new-findings-on-biological-actions-and-clinical-applications-of-royal-jelly-a-review
#15
Mozafar Khazaei, Atefe Ansarian, Elham Ghanbari
Royal jelly (RJ) is a natural bee product with great potential for use in medicine. The chemical composition of RJ indicates the presence of various bioactive substances including 10-hydroxydecanoic acid and 24-methylenecholesterol. In addition, a number of biological and pharmacological activities of RJ have been documented. The aim of this study was to review the biological and medical effects of RJ. The search was conducted in articles from electronic and scientific literature databases such as Pub Med, Science Direct, Scopus, Medline, and ISI Web of Science published from 1990 to 2017 using keywords of pharmacological, biological, and clinical effects and royal jelly...
October 13, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29027704/effect-of-royal-jelly-on-behavioural-patterns-feather-quality-egg-quality-and-some-haematological-parameters-in-laying-hens-at-the-late-stage-of-production
#16
M S El-Tarabany
The aim was to elucidate the impact of Royal Jelly (RJ) on behavioural patterns, feather cover, egg quality and some blood haematological indices in laying hens (58-64 weeks of age). A total of 108 Tetra Brown laying hens were used in the current trial. The birds were divided into three equal groups (36 birds each). The pure RJ was prepared for immediate injection subcutaneously, as follows: the first treated group (RJ1 :100 mg/kg); the second treated group (RJ2 :200 mg/kg); the control group. The eating and drinking activities in the RJ2 group were significantly (p = ...
October 13, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28992336/molecular-and-cytogenetic-effects-of-thai-royal-jelly-modulation-through-c-myc-h-tert-nrf2-ho-1-bcl2-bax-and-cyclins-in-human-lymphocytes-in-vitro
#17
Wantha Jenkhetkan, Sumon Thitiorul, Chalerm Jansom, Treetip Ratanavalachai
Royal jelly (RJ) is widely used as a food supplement for anti-aging and beauty. However, its use has been linked to asthma and hemorrhagic colitis. Since its mechanisms of toxicity have not been fully identified, we conducted an investigation to elucidate its molecular and cytogenetic effects. Using human lymphocytes in vitro, treatments with RJ (0.0005-5 mg/ml) for 3 h did not induce sister chromatid exchanges until 5 mg/ml was used. Treatments for 24 h showed a dose-dependent reduction in BCL2/BAX, c-MYC/BAX and HO-1/BAX ratios...
September 15, 2017: Mutagenesis
https://www.readbyqxmd.com/read/28982287/preventive-effects-of-royal-jelly-against-anaphylactic-response-in-a-murine-model-of-cow-s-milk-allergy
#18
Malika Guendouz, Abir Haddi, Hadria Grar, Omar Kheroua, Djamel Saidi, Hanane Kaddouri
CONTEXT: Royal jelly (RJ) has long been used to promote human health. OBJECTIVE: The current study investigated the preventive effects of RJ against the development of a systemic and intestinal immune response in mice allergic to cow's milk proteins. MATERIALS AND METHODS: Balb/c mice treated orally for seven days with RJ at doses of 0.5, 1 and 1.5 g/kg were sensitized intraperitoneally with β-lactoglobulin (β-Lg). Serum IgG and IgE anti-β-Lg were determined by an enzyme-linked immunosorbent assay (ELISA)...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28981639/nutritional-regulation-of-phenotypic-plasticity-in-a-solitary-bee-hymenoptera-megachilidae
#19
Brielle J Fischman, Theresa L Pitts-Singer, Gene E Robinson
Phenotypic plasticity involves adaptive responses to predictable environmental fluctuations and may promote evolutionary change. We studied the regulation of phenotypic plasticity in an important agricultural pollinator, the solitary alfalfa leafcutting bee (Megachile rotundata F.). Specifically, we investigated how larval nutrition affects M. rotundata diapause plasticity and how diapause plasticity affects adult female reproductive behavior. Field surveys and laboratory manipulations of aspects of larval diet demonstrated nutritional regulation of M...
October 1, 2017: Environmental Entomology
https://www.readbyqxmd.com/read/28981563/identification-of-genes-related-to-high-royal-jelly-production-in-the-honey-bee-apis-mellifera-using-microarray-analysis
#20
Hongyi Nie, Xiaoyan Liu, Jiao Pan, Wenfeng Li, Zhiguo Li, Shaowu Zhang, Shenglu Chen, Xiaoqing Miao, Nenggan Zheng, Songkun Su
China is the largest royal jelly producer and exporter in the world, and high royal jelly-yielding strains have been bred in the country for approximately three decades. However, information on the molecular mechanism underlying high royal jelly production is scarce. Here, a cDNA microarray was used to screen and identify differentially expressed genes (DEGs) to obtain an overview on the changes in gene expression levels between high and low royal jelly producing bees. We developed a honey bee gene chip that covered 11,689 genes, and this chip was hybridised with cDNA generated from RNA isolated from heads of nursing bees...
October 2, 2017: Genetics and Molecular Biology
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