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Royal jelli

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https://www.readbyqxmd.com/read/28900247/effects-of-protease-treated-royal-jelly-on-muscle-strength-in-elderly-nursing-home-residents-a-randomized-double-blind-placebo-controlled-dose-response-study
#1
Ge Meng, Honglei Wang, Yinghua Pei, Yanmei Li, Hongmei Wu, Yanqi Song, Qi Guo, Hui Guo, Shinobu Fukushima, Tomoki Tatefuji, Jiazhong Wang, Huanmin Du, Qian Su, Wen Zhang, Suxing Shen, Xiuyang Wang, Renwei Dong, Peipei Han, Tatsuma Okazaki, Ryoichi Nagatomi, Jianhua Wang, Guowei Huang, Zhong Sun, Kun Song, Kaijun Niu
Although we have found that protease-treated royal jelly (pRJ) benefit for the skeletal muscle mass and strength in the aged animals, the potential beneficial effects have not been evaluated in humans. The aim of this study was to determine whether pRJ intake had beneficial effects on muscle strength in elderly nursing home residents. One hundred and ninety-four subjects enrolled into this multicenter, randomized, double-blind, placebo-controlled study. Subjects received either placebo(Group 1), pRJ 1.2 g/d(Group 2), or 4...
September 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28892305/high-level-resistance-of-melissococcus-plutonius-clonal-complex-3-strains-to-antimicrobial-activity-of-royal-jelly
#2
Daisuke Takamatsu, Aya Osawa, Keiko Nakamura, Mikio Yoshiyama, Masatoshi Okura
Melissococcus plutonius is the causative agent of European foulbrood of honey bee larvae. Among its three genetically distinct groups (CC3, CC12, and CC13), CC3 strains have been suggested to be more virulent at the colony level. Honey bee larvae are fed royal or worker jellies by adult bees, and these jellies exhibit antimicrobial activity. Since M. plutonius orally infects larvae via brood food, we herein investigated the resistance of M. plutonius to the antimicrobial activity of royal jelly (RJ). The results obtained revealed that M...
September 11, 2017: Environmental Microbiology Reports
https://www.readbyqxmd.com/read/28879772/brain-membrane-proteome-and-phosphoproteome-reveal-molecular-basis-associating-with-nursing-and-foraging-behaviors-of-honeybee-workers
#3
Bin Han, Yu Fang, Mao Feng, Han Hu, Yue Hao, Chuan Ma, Xinmei Huo, Lifeng Meng, Xufeng Zhang, Fan Wu, Jianke Li
The brain is a vital organ in regulating complex social behaviors of honeybees including learning and memory. Knowledge of how brain membrane proteins and their phosphorylation underlie the age-related behavioral polyethism is still lacking. A hitherto age-resolved brain membrane proteome and phosphoproteome were reported in adult worker bees from two strains of honeybee (Apis mellifera ligustica): Italian bee (ITB) and Royal Jelly bee (RJB), a line selected from ITB for increased RJ outputs over 4 decades...
September 7, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28859085/plant-micrornas-in-larval-food-regulate-honeybee-caste-development
#4
Kegan Zhu, Minghui Liu, Zheng Fu, Zhen Zhou, Yan Kong, Hongwei Liang, Zheguang Lin, Jun Luo, Huoqing Zheng, Ping Wan, Junfeng Zhang, Ke Zen, Jiong Chen, Fuliang Hu, Chen-Yu Zhang, Jie Ren, Xi Chen
The major environmental determinants of honeybee caste development come from larval nutrients: royal jelly stimulates the differentiation of larvae into queens, whereas beebread leads to worker bee fate. However, these determinants are not fully characterized. Here we report that plant RNAs, particularly miRNAs, which are more enriched in beebread than in royal jelly, delay development and decrease body and ovary size in honeybees, thereby preventing larval differentiation into queens and inducing development into worker bees...
August 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28814983/honey-propolis-and-royal-jelly-a-comprehensive-review-of-their-biological-actions-and-health-benefits
#5
REVIEW
Visweswara Rao Pasupuleti, Lakhsmi Sammugam, Nagesvari Ramesh, Siew Hua Gan
BACKGROUND: There are several health benefits that honeybee products such as honey, propolis, and royal jelly claim toward various types of diseases in addition to being food. SCOPE AND APPROACH: In this paper, the effects of honey, propolis, and royal jelly on different metabolic diseases, cancers, and other diseases have been reviewed. The modes of actions of these products have also been illustrated for purposes of better understanding. KEY FINDINGS AND CONCLUSIONS: An overview of honey, propolis, and royal jelly and their biological potentials was highlighted...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28801873/transgenic-silkworms-secrete-the-recombinant-glycosylated-mrjp1-protein-of-chinese-honeybee-apis-cerana-cerana
#6
Zhengying You, Qiujie Qian, Yiran Wang, Jiaqian Che, Lupeng Ye, Lirong Shen, Boxiong Zhong
Major royal jelly protein-1 (MRJP1) is the most abundant glycoprotein of royal jelly (RJ) and is considered a potential component of functional foods. In this study, we used silkworm transgenic technology to obtain five transgenic silkworm lineages expressing the exogenous recombinant Chinese honeybee, Apis cerana cerana, protein-1 (rAccMRJP1) under the control of a fibroin light chain (Fib-L) promoter in the posterior silk glands. The protein was successfully secreted into cocoons; specifically, the highest rAccMRJP1 protein content was 0...
August 11, 2017: Transgenic Research
https://www.readbyqxmd.com/read/28793915/the-functional-property-of-royal-jelly-10-hydroxy-2-decenoic-acid-as-a-melanogenesis-inhibitor
#7
Chi-Chung Peng, Hui-Tzu Sun, I-Ping Lin, Ping-Chung Kuo, Jen-Chieh Li
BACKGROUND: It has been reported that royal jelly would reduce melanin synthesis and inhibit the expression of melanogensis related proteins and genes. In this study, we evaluate the anti-melanogenic and depigmenting activity of 10-hydroxy-2-decenoic acid (10-HDA) from royal jelly of Apis mellifera. METHODS: In this study, we assesses the 10-HDA whitening activity in comparison with the changes in the intracellular tyrosinase activity, melanin content and melanin production related protein levles in B16F1 melanoma cells after treating with 10-HDA...
August 9, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28737831/royal-jelly-lipophilic-fraction-induces-antiproliferative-effects-on-sh-sy5y-human-neuroblastoma-cells
#8
Angelo Gismondi, Eleonora Trionfera, Lorena Canuti, Gabriele Di Marco, Antonella Canini
Royal jelly (RJ) is one the most important bee product because it strongly influences the larval development in the hive, including the queen bee. In literature, RJ is known for its antioxidant, immunoregulatory, antifungal, antibiotical, erythropoietic, hypoglycemic, anticholesteremic, antithyroidic, anti-osteoporotic and estrogenic properties. However, it is surprising how rare the scientific evidence about RJ antineoplastic capacity are. That being said, we investigated, for the first time, the in vitro bioactivity of six different RJs on the growth of three different mammalian cell lines: immortalized murine myoblasts (C2C12), human prostate cancer (PC3) and human neuroblastoma (SH-SY5Y)...
July 24, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28732753/gene-expression-changes-in-honey-bees-induced-by-sublethal-imidacloprid-exposure-during-the-larval-stage
#9
Ming-Cheng Wu, Yu-Wen Chang, Kuang-Hui Lu, En-Cheng Yang
Honey bee larvae exposed to sublethal doses of imidacloprid show behavioural abnormalities as adult insects. Previous studies have demonstrated that this phenomenon originates from abnormal neural development in response to imidacloprid exposure. Here, we further investigated the global gene expression changes in the heads of newly emerged adults and observed that 578 genes showed more than 2-fold changes in gene expression after imidacloprid exposure. This information might aid in understanding the effects of pesticides on the health of pollinators...
July 18, 2017: Insect Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28709905/royal-jelly-decreases-corticosterone-levels-and-improves-the-brain-antioxidant-system-in-restraint-and-cold-stressed-rats
#10
Renata Roland Teixeira, Adriele Vieira de Souza, Leonardo Gomes Peixoto, Helen Lara Machado, Douglas Carvalho Caixeta, Danielle Diniz Vilela, Nathalia Belele Baptista, Celso Rodrigues Franci, Foued Salmen Espindola
Restraint and cold stress induces the hypothalamic-pituitary-adrenal (HPA) axis to release corticosterone from the adrenal gland, which can worsen the antioxidant defense system in the central nervous system. Here, we investigated the corticosterone levels and the antioxidant defense system in the cerebellum and brain, as well as in its isolated regions, such as cerebral cortex, striatum and hippocampus of stressed rats supplemented with royal jelly (RJ). Wistar rats were supplemented with RJ for 14days and the stress induction started on the 7th day...
August 10, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28701955/therapeutic-properties-of-bioactive-compounds-from-different-honeybee-products
#11
REVIEW
Laura Cornara, Marco Biagi, Jianbo Xiao, Bruno Burlando
Honeybees produce honey, royal jelly, propolis, bee venom, bee pollen, and beeswax, which potentially benefit to humans due to the bioactives in them. Clinical standardization of these products is hindered by chemical variability depending on honeybee and botanical sources, but different molecules have been isolated and pharmacologically characterized. Major honey bioactives include phenolics, methylglyoxal, royal jelly proteins (MRJPs), and oligosaccharides. In royal jelly there are antimicrobial jelleins and royalisin peptides, MRJPs, and hydroxy-decenoic acid derivatives, notably 10-hydroxy-2-decenoic acid (10-HDA), with antimicrobial, anti-inflammatory, immunomodulatory, neuromodulatory, metabolic syndrome preventing, and anti-aging activities...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28651989/unraveling-the-venom-components-of-an-encyrtid-endoparasitoid-wasp-diversinervus-elegans
#12
Nai-Yong Liu, Jin-Qiang Wang, Zu-Bing Zhang, Jing-Mei Huang, Jia-Ying Zhu
The encyrtid parasitoid, Diversinervus elegans (Hymenoptera: Encyrtidae), is a natural enemy of the notorious scale pests belonging to the family of Coccidae. Venom containing a rich source of bioactive molecules is a key virulent factor used to regulate host physiology by parasitoids. Although knowledge regarding venom constituents accumulated from limited parasitoids has provided insights into their roles in host-parasitoid interaction, toxins involving in manipulating scale physiology remain sparsely documented...
June 24, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28572315/deeper-insight-in-beehives-metagenomes-of-royal-jelly-pollen-and-honey-from-lavender-chestnut-and-fir-honeydew-and-epiphytic-and-endophytic-microbiota-of-lavender-and-rose-flowers
#13
Julien Crovadore, François Gérard, Romain Chablais, Bastien Cochard, Karl Kristian Bergman Jensen, François Lefort
Microbiota of beehive products are very little known. We report here for the first time six metagenomes of royal jelly, pollen, and different types of honey from wild and cultivated lavender, chestnut, and fir honeydew. Four metagenomes of epiphytic and endophytic microbiota of lavender and rose flowers are also reported.
June 1, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28548561/effect-of-honey-and-royal-jelly-against-cisplatin-induced-nephrotoxicity-in-patients-with-cancer
#14
Hasnaa Osama, Aya Abdullah, Bassma Gamal, Dina Emad, Doha Sayed, Eman Hussein, Eman Mahfouz, Joy Tharwat, Sally Sayed, Shrouk Medhat, Treza Bahaa, Mohamed E A Abdelrahim
OBJECTIVES: Cisplatin constitutes one of the most potent antineoplastic drugs; however, nephrotoxicity limited its eligibility for optimal clinical use. This study was designed to evaluate the role of honey and royal jelly with antioxidant properties in the protection of cisplatin-induced acute kidney injury in patients with cancer. METHODS: Patients with cancer assigned for cisplatin chemotherapy were randomly divided into bee honey and royal jelly groups pretreated before the initiation and during cisplatin chemotherapeutic regimen and control group on cisplatin only...
July 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28468244/propolis-counteracts-some-threats-to-honey-bee-health
#15
REVIEW
Michael Simone-Finstrom, Renata S Borba, Michael Wilson, Marla Spivak
Honey bees (Apis mellifera) are constantly dealing with threats from pathogens, pests, pesticides and poor nutrition. It is critically important to understand how honey bees' natural immune responses (individual immunity) and collective behavioral defenses (social immunity) can improve bee health and productivity. One form of social immunity in honey bee colonies is the collection of antimicrobial plant resins and their use in the nest architecture as propolis. We review research on the constitutive benefits of propolis on the honey bee immune system, and its known therapeutic, colony-level effects against the pathogens Paenibacillus larvae and Ascosphaera apis...
April 29, 2017: Insects
https://www.readbyqxmd.com/read/28428804/morphogenesis-of-honeybee-hypopharyngeal-gland-during-pupal-development
#16
Sascha Peter Klose, Daniel Rolke, Otto Baumann
BACKGROUND: The hypopharyngeal gland of worker bees contributes to the production of the royal jelly fed to queens and larvae. The gland consists of thousands of two-cell units that are composed of a secretory cell and a duct cell and that are arranged in sets of about 12 around a long collecting duct. RESULTS: By fluorescent staining, we have examined the morphogenesis of the hypopharyngeal gland during pupal life, from a saccule lined by a pseudostratified epithelium to the elaborate organ of adult worker bees...
2017: Frontiers in Zoology
https://www.readbyqxmd.com/read/28407954/total-determination-of-chloramphenicol-residues-in-foods-by-liquid-chromatography-tandem-mass-spectrometry
#17
Hiroyuki Kikuchi, Takatoshi Sakai, Reiko Teshima, Satoru Nemoto, Hiroshi Akiyama
A simple and sensitive analytical method for the determination of chloramphenicol (CAP) and chloramphenicol glucuronide (CAPG) residues in foods such as livestock products, seafood, honey and royal jelly was developed. The method comprises solvent extraction with methanol, enzymatic hydrolysis with β-glucuronidase and clean-up using a hydrophilic lipophilic balanced copolymer solid phase extraction column. To determine the optimal conditions for the complete enzymatic hydrolysis of CAPG, we examined the effect of enzyme concentration and incubation time on the hydrolysis...
September 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28367370/longevity-extension-of-worker-honey-bees-apis-mellifera-by-royal-jelly-optimal-dose-and-active-ingredient
#18
Wenchao Yang, Yuanyuan Tian, Mingfeng Han, Xiaoqing Miao
In the Western honey bee, Apis mellifera, queens and workers have different longevity although they share the same genome. Queens consume royal jelly (RJ) as the main food throughout their life, including as adults, but workers only eat worker jelly when they are larvae less than 3 days old. In order to explore the effect of RJ and the components affecting longevity of worker honey bees, we first determined the optimal dose for prolonging longevity of workers as 4% RJ in 50% sucrose solution, and developed a method of obtaining long lived workers...
2017: PeerJ
https://www.readbyqxmd.com/read/28362493/effect-of-major-royal-jelly-proteins-on-spatial-memory-in-aged-rats-metabolomics-analysis-in-urine
#19
Di Chen, Fang Liu, Jian-Bo Wan, Chao-Qiang Lai, Li-Rong Shen
Royal jelly (RJ) produced by worker honeybees is the sole food for the queen bee throughout her life as well as the larvae of worker bees for the first 3 days after hatching. Supplementation of RJ in the diet has been shown to increase spatial memory in rodents. However, the key constituents in RJ responsible for improvement of cognitive function are unknown. Our objective was to determine if the major royal jelly proteins (MRJPs) extracted from RJ can improve the spatial memory of aged rats. The spatial memory assay using the Morris water maze test was administered once to rats after a 14-week feeding...
April 19, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28355995/new-advances-in-infant-feeding-new-products-and-novel-technologies
#20
M C Pina-Pérez, A Martínez, D Rodrigo
BACKGROUND: Breastfeeding is the best way to provide ideal food for infants. However, there are many situations in which breastfeeding is unviable (maternal illness, hygiene problems, intravenous feeding requirement, storage). Safe, efficient, and nutritious products should be offered by the industry to mothers and healthcare professionals as an alternative. OBJECTIVE: The present review aims to update the state of the art regarding the most innovative developments in infant feeding formulation and, the promising novel technologies that are being investigated to achieve a balance between the microbiological stability, organoleptic and nutritional value of babyfood...
March 28, 2017: Recent Patents on Food, Nutrition & Agriculture
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