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https://www.readbyqxmd.com/read/28924591/safety-and-efficacy-of-coaxial-lumen-apposing-metal-stents-in-the-management-of-refractory-gastrointestinal-luminal-strictures-a-multicenter-study
#1
Fateh Bazerbachi, Jason D Heffley, Barham K Abu Dayyeh, Jose Nieto, Eric J Vargas, Tarek Sawas, Raja Zaghlol, Navtej S Buttar, Mark D Topazian, Louis M Wong Kee Song, Michael Levy, Steve Keilin, Qiang Cai, Field F Willingham
BACKGROUND AND AIMS:  Benign gastrointestinal (GI) strictures are often refractory to standard endoscopic interventions. Fully covered coaxial lumen-apposing metal stents (LAMS) have emerged as a novel therapy for these strictures. The aim of this study was to evaluate the safety and efficacy of LAMS for refractory GI strictures. PATIENTS AND METHODS:  A retrospective analysis was performed for patients who underwent LAMS placement for benign luminal strictures in three US centers between January 2014 and December 2016...
September 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28919145/outcomes-of-therapy-for-vulvar-manifestation-of-inflammatory-bowel-disease-in-adolescents
#2
Katherine E Debiec, Scott D Lee, Ghassan T Wahbeh, Anne-Marie Amies Oelschlager
BACKGROUND: Vulvar manifestations of inflammatory bowel disease (IBD) are variable in presentation and challenging to treat. We describe vulvar manifestations and treatment response in adolescent females with IBD. CASES: We identified six patients with vulvar manifestations of IBD and documented treatments by retrospective chart review. Vulvar symptoms occurred without gastrointestinal (GI) symptoms in one patient. For the remaining five patients, two had GI symptoms prior to the onset of vulvar symptoms (mean time difference 4...
September 14, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28916889/teaching-peroral-endoscopic-myotomy-poem-to-surgeons-in-practice-an-into-the-fire-pre-post-test-curriculum
#3
Tomokazu Kishiki, Brittany Lapin, Chi Wang, Brandon Jonson, Lava Patel, Matthew Zapf, Matthew Gitelis, Maria A Cassera, Lee L Swanström, Michael B Ujiki
INTRODUCTION: With the increasing adoption of peroral endoscopic myotomy (POEM) as a first-line therapy for achalasia as well as a growing list of other indications, it is apparent that there is a need for effective training methods for both endoscopists in training and those already in practice. We present a hands-on-focused with pre- and post-testing methodology to teach these skills. METHODS: Six POEM courses were taught by 11 experienced POEM endoscopists at two independent simulation laboratories...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28914249/visual-pedagogy-and-probiotics-for-hearing-impaired-children-a-pilot-study
#4
Amrita Sujlana, Ruchika Goyal, Parampreet Pannu, Shireen Opal, Palki Bansal
CONTEXT: Oral health care for children with special needs remains largely unmet. It is important that we should focus on preventive strategies for special children to help curtail and prevent oral diseases. AIM: This study aimed to assess the effect of visual pedagogy and probiotic mouth rinse on the periodontal health of hearing impaired children. MATERIALS AND METHODOLOGY: The study cohort consisted of twenty children with hearing impairment (HI) and 20 age-matched healthy children...
October 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28905292/effects-of-laparoscopic-roux-en-y-gastric-bypass-for-type-2-diabetes-mellitus-comparison-of-bmi-%C3%A2-30-and-%C3%A2-30%C3%A2-kg-m-2
#5
Zhigang Ke, Fan Li, Jing Chen, Yu Gao, Xunmei Zhou, Fang Sun, Chunxue Li, Baohua Liu, Qiang Li, Zhiming Zhu, Weidong Tong
BACKGROUND: Recently, many studies focused on type 2 diabetes mellitus (T2DM) patients with body mass index (BMI) < 30 kg/m(2) and suggested that those patients might benefit from Roux-en-Y gastric bypass (RYGB). However, evidence on its effectiveness to improve T2DM patients with BMI < 30 kg/m(2) is still lacking. The aim of this study is to explore whether T2DM patients with BMI < 30 kg/m(2) get similar surgical effect from RYGB compared with those patients with BMI > 30 kg/m(2)...
September 13, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28900775/specialization-and-production-cost-efficiency-evidence-from-ambulatory-surgery-centers
#6
Kathleen Carey, Jean M Mitchell
In the U.S. health care sector, the economic logic of specialization as an organizing principle has come under active debate in recent years. An understudied case is that of ambulatory surgery centers (ASCs), which recently have become the dominant provider of specific surgical procedures. While the majority of ASCs focus on a single specialty, a growing number are diversifying to offer a wide range of surgical services. We take a multiple output cost function approach to an empirical investigation that compares production economies in single specialty ASCs with those in multispecialty ASCs...
September 12, 2017: International Journal of Health Economics and Management
https://www.readbyqxmd.com/read/28894776/diagnostic-accuracy-of-computed-tomography-scan-in-detection-of-upper-gastrointestinal-tract-injuries-following-caustic-ingestion
#7
Hooman Bahrami-Motlagh, Mohammad Hadizadeh-Neisanghalb, Hassan Peyvandi
INTRODUCTION: Endoscopy is an invasive procedure and finding noninvasive alternative tools in detection of probable upper gastrointestinal (GI) tract injuries following caustic ingestion is an area of interest. The present study aimed to evaluate the screening performance characteristics of thoraco-abdominal computed tomography (CT) scan in this regard. METHODS: This prospective cross sectional study was conducted on patients presenting to emergency department following acute caustic ingestion...
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/28881875/efficacy-safety-and-long-term-outcome-of-serial-endoscopic-balloon-dilation-for-upper-gastrointestinal-crohn-s-disease-associated-strictures-a-cohort-study
#8
Amandeep Singh, Neha Agrawal, Satya Kurada, Rocio Lopez, Hermann Kessler, Jessica Philpott, Bo Shen, Bret Lashner, Florian Rieder
Background: Gastric and duodenal Crohn's disease [CD]-associated strictures are rare. Evidence on endoscopic balloon dilation [EBD] of upper gastrointestinal [GI] CD strictures is limited, in particular in respect to serial dilations. Methods: Prospective short- and long-term outcome data as well as complication rates on a cohort of upper GI CD-associated stricture dilations [stomach and duodenum] were collected from 1999 to 2015. Factors linked with clinical and technical success, long-term efficacy and complication rates were investigated...
September 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28879803/practice-patterns-of-retrievable-inferior-vena-cava-filters-and-predictors-of-filter-retrieval-in-patients-with-pulmonary-embolism
#9
Jieun Kang, Heung-Kyu Ko, Ji Hoon Shin, Gi-Young Ko, Kyung-Wook Jo, Jin Won Huh, Yeon-Mok Oh, Sang-Do Lee, Jae Seung Lee
Retrievable inferior vena cava (IVC) filters are increasingly used in patients with venous thromboembolism (VTE) who have contraindications to anticoagulant therapy. However, previous studies have shown that many retrievable filters are left permanently in patients. This study aimed to identify the common indications for IVC filter insertion, the filter retrieval rate, and the predictive factors for filter retrieval attempts. To this end, a retrospective cohort study was performed at a tertiary care center in South Korea between January 2010 and May 2016...
September 1, 2017: Vascular Medicine
https://www.readbyqxmd.com/read/28874632/duodenal-gastrointestinal-stromal-tumor-a-case-report
#10
Antonino Tornambe, Giuseppe Tornambe
AIM: To report an another case of duodenal GIST in patient that was treated with Whipple procedure. MATERIAL OF STUDY: We report a case of 69 years old men that was admitted with melena. The preoperative investigations suggested a suspected duodenal GIST.A Whipple pancreatico-duodenectomy was performed. Only 3-5% of GISTs occur in the duodenum. DISCUSSION: GIST were described as a separate entity by Mazur and Clark in 1983. These tumors are the most common among mesenchymal tumors of the gastrointeninal tract...
July 25, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28874418/therapeutic-endoscopy-related-gi-bleeding-and-thromboembolic-events-in-patients-using-warfarin-or-direct-oral-anticoagulants-results-from-a-large-nationwide-database-analysis
#11
Naoyoshi Nagata, Hideo Yasunaga, Hiroki Matsui, Kiyohide Fushimi, Kazuhiro Watanabe, Junichi Akiyama, Naomi Uemura, Ryota Niikura
OBJECTIVE: To compare the risks of postendoscopy outcomes associated with warfarin with direct oral anticoagulants (DOACs), taking into account heparin bridging and various types of endoscopic procedures. DESIGN: Using the Japanese Diagnosis Procedure Combination database, we identified 16 977 patients who underwent 13 types of high-risk endoscopic procedures and took preoperative warfarin or DOACs from 2014 to 2015. One-to-one propensity score matching was performed to compare postendoscopy GI bleeding and thromboembolism between the warfarin and DOAC groups...
September 5, 2017: Gut
https://www.readbyqxmd.com/read/28872161/temporal-changes-in-impedance-of-implanted-adults-for-various-cochlear-segments
#12
C A Leone, F Mosca, R Grassia
Electrode impedance (EI) is the first objective assessment carried out during the surgical procedure and follow-up of cochlear implanted patients. This measure provides information on the integrity of electrodes and on the surrounding environment. It is one of the main factors responsible for energy consumption of the cochlear implant (CI). The aim of our study is to investigate changes over time in EI in adult recipients implanted with the perimodiolar array by comparing differences in various cochlear segments...
August 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28867728/development-of-a-high-throughput-assay-for-inhibitors-of-the-polo-box-domain-of-polo-like-kinase-1-based-on-time-resolved-fluorescence-energy-transfer
#13
Tae Gi Kim, Ju Hee Lee, Mi Young Lee, Ka-Ul Kim, Jeong Hyun Lee, Chi Hoon Park, Byung Ho Lee, Kwang-Seok Oh
Although enzyme-linked immunosorbent assay (ELISA) technology has been widely accepted for binding assays against the polo-box domain (PBD) of polo-like kinase-1 (Plk1), these assays have a limitation-related heterogeneous procedure, such as multiple incubations and washing steps to apply high-throughput screenings (HTSs). In the present study, a Plk1-PBD binding assay based on time-resolved fluorescence energy transfer (TR-FRET) was developed for HTS of PBD-binding inhibitors. The TR-FRET-based Plk1-PBD binding assay is sensitive and robust and can be miniaturized into the 384-well plate-based format...
2017: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28861543/interviews-with-patients-and-providers-on-transgender-and-gender-nonconforming-health-data-collection-in-the-electronic-health-record
#14
M J Dunne, Lewis A Raynor, Erika K Cottrell, William J A Pinnock
Purpose: Meaningful use (MU) and Uniform Data Systems (UDSs) are calling for the collection of gender identity (GI) in electronic health record (EHR) systems; however, many transgender and nonconforming (TGNC) patients may not feel safe disclosing their GI and the data collection is not designed to guide care provision. This study explores the complexities surrounding the inclusion of GI in EHR data collection and how it can best serve patients and providers. Methods: Using a semistructured interview format, TGNC patients (n=7) and providers (n=5) who care for TGNC patients were asked about data collection procedures and the use of these data within community health centers in Oregon...
2017: Transgender Health
https://www.readbyqxmd.com/read/28856596/estimation-of-human-norovirus-infectivity-from-environmental-water-samples-by-in-situ-capture-rt-qpcr-method
#15
Peng Tian, David Yang, Lei Shan, Qianqian Li, Danlei Liu, Dapeng Wang
Human noroviruses (HuNoVs) are highly infectious viruses for which water is an important medium of transmission. In this study, we explored a new in situ capture RT-qPCR (ISC-RT-qPCR) methodology to estimate the infectivity of HuNoV in environmental water samples. This assay was based on capturing encapsidated HuNoV by viral receptors, followed by in situ amplification of the captured viral genomes by RT-qPCR. We demonstrated that the ISC-RT-qPCR did not capture and enable signal amplification of heat-denatured Tulane Virus (TV) and HuNoVs...
August 30, 2017: Food and Environmental Virology
https://www.readbyqxmd.com/read/28844920/reappraisal-of-pediatric-diastatic-skull-fractures-in-the-3-dimensional-ct-era-clinical-characteristics-and-comparison-of-diagnostic-accuracy-of-simple-skull-x-ray-2-dimensional-ct-and-3-dimensional-ct
#16
Sook Young Sim, Hyun Gi Kim, Soo Han Yoon, Jong Wook Choi, Sung Min Cho
PURPOSE: Diastatic skull fractures (DSFs) in children are difficult to detect in skull x-rays before they develop into growing skull fractures, and therefore little information is available on this topic. However, recent advances in 3 dimensional CT (3DCT) imaging technology enable more accurate diagnoses of almost all forms of skull fractures. The present study was undertaken to document the clinical characteristics of DSFs in children and to determine whether 3DCT enhances diagnostic accuracy...
August 24, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28828588/factitious-disorder-a-rare-cause-of-haematemesis
#17
Michael McFarlane, Jayne Eaden, Nicola Burch, Ben Disney
Acute upper gastrointestinal (GI) bleeding is a common condition in the UK with 50-70,000 admissions per year. In 20% of cases no cause can be found on endoscopy. Here, we present the case of a young female patient who was admitted on three occasions with large volume haematemesis and bleeding from other sites. She was extensively investigated and underwent multiple endoscopic procedures. She was eventually diagnosed with factitious disorder after concerns were raised about the inconsistent nature of her presentations...
August 21, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28827870/effect-of-listening-to-vedic-chants-and-indian-classical-instrumental-music-on-patients-undergoing-upper-gastrointestinal-endoscopy-a-randomized-control-trial
#18
Anita Padam, Neetu Sharma, O S K S Sastri, Shivani Mahajan, Rajesh Sharma, Deepak Sharma
BACKGROUND: A high level of preoperative anxiety is common among patients undergoing medical and surgical procedures. Anxiety impacts of gastroenterological procedures on psychological and physiological responses are worth consideration. AIMS AND OBJECTIVES: To analyze the effect of listening to Vedic chants and Indian classical instrumental music on anxiety levels and on blood pressure (BP), heart rate (HR), and oxygen saturation in patients undergoing upper gastrointestinal (GI) endoscopy...
April 2017: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28822392/optimal-modified-frailty-index-cutoff-in-older-gastrointestinal-cancer-patients
#19
Mary Garland, Fang-Chi Hsu, Perry Shen, Clancy J Clark
The newly characterized modified frailty index (mFI) is a robust predictor of postoperative outcomes for surgical patients. The present study investigates the optimal cutoff for mFI specifically in older gastrointestinal (GI) cancer patients undergoing surgery. All patients more than 60 years old who underwent surgery for a GI malignancy (esophagus, stomach, colon, rectum, pancreas, liver, and bile duct) were identified in the 2005 to 2012 National Surgical Quality Improvement Program, Participant Use Data File (NSQIP PUF)...
August 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28815078/surgical-anatomy-of-the-omental-bursa-and-the-stomach-based-on-a-minimally-invasive-approach-different-approaches-and-technical-steps-to-resection-and-lymphadenectomy
#20
Hylke J F Brenkman, Nicole I van der Wielen, Jelle P Ruurda, Maarten S van Leeuwen, Joris J G Scheepers, Donald L van der Peet, Richard van Hillegersberg, Ronald L A W Bleys, Miguel A Cuesta
BACKGROUND: It is imperative for surgeons to have a proper knowledge of the omental bursa in order to perform an adequate dissection during minimally invasive surgery (MIS) of the upper gastrointestinal (GI) tract. This study aimed to describe (1) the various approaches which can be used to enter the bursa and to perform a complete lymphadenectomy, (2) the boundaries and anatomical landmarks of the omental bursa as seen during MIS, and (3) whether a bursectomy should be performed for oncological reasons in upper GI cancer...
July 2017: Journal of Thoracic Disease
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