keyword
MENU ▼
Read by QxMD icon Read
search

Sudan virus

keyword
https://www.readbyqxmd.com/read/27902321/the-serology-of-ebolavirus-a-wider-geographical-range-a-wider-genus-of-viruses-or-a-wider-range-of-virulence
#1
Magdalena Formella, Derek Gatherer
Viruses of the genus Ebolavirus are the causative agents of Ebola virus disease (EVD), of which there have been only 25 recorded outbreaks since the discovery of Zaire and Sudan ebolaviruses in the late 1970s. Until the west African outbreak commencing in late 2013, EVD was confined to an area of central Africa stretching from the coast of Gabon through the Congo river basin and eastward to the Great Lakes. Nevertheless, population serological studies since 1976, most of which were carried out in the first two decades after that date, have suggested a wider distribution and more frequent occurrence across tropical Africa...
October 21, 2016: Journal of General Virology
https://www.readbyqxmd.com/read/27833652/molecular-detection-of-epstein-barr-virus-in-nasopharyngeal-carcinoma-among-sudanese-population
#2
Ali Edreis, Mona Ali Mohamed, Nouh S Mohamed, Emmanuel E Siddig
BACKGROUND: Nasopharyngeal carcinoma (NPC) is the most common cancer arising from the nasopharynx that varies significantly from other cancers of the head and neck in its occurrence, causes, clinical behavior, and treatment. NPC caused by an interaction between infection with EBV and environmental and genetic factors, encompasses a multistep oncogenic process. The frequency of Epstein-Barr virus EBV among nasopharyngeal carcinoma is well known worldwide, however, in the Sudan there is barely a published data...
2016: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/27793730/full-genome-sequence-analysis-of-a-newly-emerged-qx-like-infectious-bronchitis-virus-from-sudan-reveals-distinct-spots-of-recombination
#3
Mahmoud M Naguib, Dirk Höper, Abdel-Satar Arafa, Ahmed M Setta, Mohamed Abed, Isabella Monne, Martin Beer, Timm C Harder
Infectious bronchitis virus (IBV) infection continues to cause economically important diseases in poultry while different geno- and serotypes continue to circulate globally. Two infectious bronchitis viruses (IBV) were isolated from chickens with respiratory disease in Sudan. Sequence analysis of the hypervariable regions of the S1 gene revealed a close relation to the QX-like genotype which has not been detected in Sudan before. Whole genome analysis of IBV/Ck/Sudan/AR251-15/2014 isolate by next generation sequencing revealed a genome size of 27,646 nucleotides harbouring 13 open reading frames: 5'-1a-1b-S-3a-3b-E-M-4b-4c-5a-5b-N-6b-3'...
December 2016: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/27782061/a%C3%A2-single%C3%A2-lineage%C3%A2-of%C3%A2-hepatitis%C3%A2-e%C3%A2-virus%C3%A2-causes%C3%A2-both%C3%A2-outbreaks%C3%A2-and%C3%A2-sporadic%C3%A2-hepatitis%C3%A2-in%C3%A2-sudan
#4
Adel Hussein Elduma, Mai Mohammed Adam Zein, Marie Karlsson, Isam M E Elkhidir, Heléne Norder
Few studies have reported sporadic hepatitis E virus (HEV) infections during non-outbreak periods in Africa. In this study, the prevalence of HEV infection in Sudan was investigated in 432 patients with acute hepatitis from 12 localities in North Kordofan, and from 152 patients involved in smaller outbreaks of hepatitis in the neighbouring Darfur. HEV infection was diagnosed in 147 (25%) patients: 98 from Kordofan and 49 from Darfur. The mortality was 10%; six of the patients who died from the infection were pregnant women...
October 6, 2016: Viruses
https://www.readbyqxmd.com/read/27764211/metagenomic-based-screening-and-molecular-characterization-of-cowpea-infecting-viruses-in-burkina-faso
#5
Essowè Palanga, Denis Filloux, Darren P Martin, Emmanuel Fernandez, Daniel Gargani, Romain Ferdinand, Jean Zabré, Zakaria Bouda, James Bouma Neya, Mahamadou Sawadogo, Oumar Traore, Michel Peterschmitt, Philippe Roumagnac
Cowpea, (Vigna unguiculata L. (Walp)) is an annual tropical grain legume. Often referred to as "poor man's meat", cowpea is one of the most important subsistence legumes cultivated in West Africa due to the high protein content of its seeds. However, African cowpea production can be seriously constrained by viral diseases that reduce yields. While twelve cowpea-infecting viruses have been reported from Africa, only three of these have so-far been reported from Burkina Faso. Here we use a virion-associated nucleic acids (VANA)-based metagenomics method to screen for the presence of cowpea viruses from plants collected from the three agro-climatic zones of Burkina Faso...
2016: PloS One
https://www.readbyqxmd.com/read/27755595/the-ebola-virus-vp30-np-interaction-is-a-regulator-of-viral-rna-synthesis
#6
Robert N Kirchdoerfer, Crystal L Moyer, Dafna M Abelson, Erica Ollmann Saphire
Filoviruses are capable of causing deadly hemorrhagic fevers. All nonsegmented negative-sense RNA-virus nucleocapsids are composed of a nucleoprotein (NP), a phosphoprotein (VP35) and a polymerase (L). However, the VP30 RNA-synthesis co-factor is unique to the filoviruses. The assembly, structure, and function of the filovirus RNA replication complex remain unclear. Here, we have characterized the interactions of Ebola, Sudan and Marburg virus VP30 with NP using in vitro biochemistry, structural biology and cell-based mini-replicon assays...
October 2016: PLoS Pathogens
https://www.readbyqxmd.com/read/27692776/association-of-rift-valley-fever-virus-infection-with-miscarriage-in-sudanese-women-a-cross-sectional-study
#7
Maria Baudin, Ammar M Jumaa, Huda J E Jomma, Mubarak S Karsany, Göran Bucht, Jonas Näslund, Clas Ahlm, Magnus Evander, Nahla Mohamed
BACKGROUND: Rift Valley fever virus is an emerging mosquito-borne virus that causes infections in animals and human beings in Africa and the Arabian Peninsula. Outbreaks of Rift Valley fever lead to mass abortions in livestock, but such abortions have not been identified in human beings. Our aim was to investigate the cause of miscarriages in febrile pregnant women in an area endemic for Rift Valley fever. METHODS: Pregnant women with fever of unknown origin who attended the governmental hospital of Port Sudan, Sudan, between June 30, 2011, and Nov 17, 2012, were sampled at admission and included in this cross-sectional study...
November 2016: Lancet Global Health
https://www.readbyqxmd.com/read/27659611/an-8-year-retrospective-study-of-human-visceral-leishmaniasis
#8
Juliana Ferreira Barbosa, Sônia Maria de Figueiredo, Sandra Lyon, Rachel Basques Caligiorne
Visceral leishmaniasis (VL) is azooanthroponosis affecting both rural and peri-urban areas, and can also spread into urban areas. Although more than 90% of new cases are reported from six countries: Bangladesh, Brazil, Ethiopia, India, South Sudan and Sudan, VL has emerged in many countries in the world, presenting new cases in new countries of occurrence. Thus, studies concerning epidemiological aspects in different world regions are very meaningful.In this purpose, this study aimed analyze 89 cases of VL, treated between June 2006 and June 2014 at Eduardo de Menezes Hospital (HEM), a Reference Center of Infectious Diseases situated in Belo Horizonte, in Minas Gerais state, Brazil...
September 21, 2016: Current Clinical Pharmacology
https://www.readbyqxmd.com/read/27587634/analytical-validation-of-the-reebov-antigen-rapid-test-for-point-of-care-diagnosis-of-ebola-virus-infection
#9
Robert W Cross, Matthew L Boisen, Molly M Millett, Diana S Nelson, Darin Oottamasathien, Jessica N Hartnett, Abigal B Jones, Augustine Goba, Mambu Momoh, Mohamed Fullah, Zachary A Bornholdt, Marnie L Fusco, Dafna M Abelson, Shunichiro Oda, Bethany L Brown, Ha Pham, Megan M Rowland, Krystle N Agans, Joan B Geisbert, Megan L Heinrich, Peter C Kulakosky, Jeffrey G Shaffer, John S Schieffelin, Brima Kargbo, Momoh Gbetuwa, Sahr M Gevao, Russell B Wilson, Erica Ollmann Saphire, Kelly R Pitts, Sheik Humarr Khan, Donald S Grant, Thomas W Geisbert, Luis M Branco, Robert F Garry
BACKGROUND:  Ebola virus disease (EVD) is a severe viral illness caused by Ebola virus (EBOV). The 2013-2016 EVD outbreak in West Africa is the largest recorded, with >11 000 deaths. Development of the ReEBOV Antigen Rapid Test (ReEBOV RDT) was expedited to provide a point-of-care test for suspected EVD cases. METHODS:  Recombinant EBOV viral protein 40 antigen was used to derive polyclonal antibodies for RDT and enzyme-linked immunosorbent assay development...
October 15, 2016: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27571900/passive-immunotherapy-assessment-of-convalescent-serum-against-ebola-virus-makona-infection-in-nonhuman-primates
#10
Chad E Mire, Joan B Geisbert, Krystle N Agans, Emily P Thi, Amy C H Lee, Karla A Fenton, Thomas W Geisbert
BACKGROUND:  Convalescent serum and blood were used to treat patients during outbreaks of Zaire ebolavirus (ZEBOV) infection in 1976 and 1995, with inconclusive results. During the recent 2013-2016 West African epidemic, serum/plasma from survivors of ZEBOV infection was used to treat patients in the affected countries and several repatriated patients. The effectiveness of this strategy remains unknown. METHODS:  Nine rhesus monkeys were experimentally infected with ZEBOV-Makona...
October 15, 2016: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27549586/evaluation-of-realstar-reverse-transcription-polymerase-chain-reaction-kits-for-filovirus-detection-in-the-laboratory-and-field
#11
Toni Rieger, Romy Kerber, Hussein El Halas, Elisa Pallasch, Sophie Duraffour, Stephan Günther, Stephan Ölschläger
BACKGROUND:  Diagnosis of Ebola virus (EBOV) disease (EVD) requires laboratory testing. METHODS:  The RealStar Filovirus Screen reverse transcription-polymerase chain reaction (RT-PCR) kit and the derived RealStar Zaire Ebolavirus RT-PCR kit were validated using in vitro transcripts, supernatant of infected cell cultures, and clinical specimens from patients with EVD. RESULTS:  The Filovirus Screen kit detected EBOV, Sudan virus, Taï Forest virus, Bundibugyo virus, Reston virus, and Marburg virus and differentiated between the genera Ebolavirus and Marburgvirus The amount of filovirus RNA that could be detected with a probability of 95% ranged from 11 to 67 RNA copies/reaction on a LightCycler 480 II...
October 15, 2016: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27494600/ecological-contexts-of-index-cases-and-spillover-events-of-different-ebolaviruses
#12
Seth D Judson, Robert Fischer, Andrew Judson, Vincent J Munster
Ebola virus disease afflicts both human and animal populations and is caused by four ebolaviruses. These different ebolaviruses may have distinct reservoir hosts and ecological contexts that determine how, where, and when different ebolavirus spillover events occur. Understanding these virus-specific relationships is important for preventing transmission of ebolaviruses from wildlife to humans. We examine the ecological contexts surrounding 34 human index case infections of ebolaviruses from 1976-2014. Determining possible sources of spillover from wildlife, characterizing the environment of each event, and creating ecological niche models to estimate habitats suitable for spillover, we find that index case infections of two ebolaviruses, Ebola virus and Sudan virus, have occurred under different ecological contexts...
August 2016: PLoS Pathogens
https://www.readbyqxmd.com/read/27430562/characterization-of-a-new-cucurbit-infecting-ipomovirus-from-sudan
#13
Cécile Desbiez, Eric Verdin, Mark Tepfer, Catherine Wipf-Scheibel, Pauline Millot, Gasim Dafalla, Hervé Lecoq
Two members of the genus Ipomovirus (family Potyviridae) are known to infect cucurbits: cucumber vein yellowing virus (CVYV), which is emerging throughout the Mediterranean Basin, and squash vein yellowing virus (SqVYV), which has been described in America and the Caribbean Basin, and more recently in Israel. In this work, an ipomovirus different from CVYV and SqVYV, tentatively named coccinia mottle virus (CocMoV), was detected in a sample of the cucurbit Coccinia grandis collected in central Sudan in 2012...
October 2016: Archives of Virology
https://www.readbyqxmd.com/read/27419101/phylogenetic-analysis-of-some-newcastle-disease-virus-isolates-from-the-sudan
#14
N A Elmardi, M A Bakheit, A I Khalafalla
A reverse transcription-polymerase chain reaction (RT-PCR) was used to amplify 1412 bp of the fusion protein gene (F gene) of four Newcastle disease virus (NDV) isolates; two velogenic (TY-1/90 and DIK-90) and two lentogenic isolates (Dongla 88/1 and GD.S.1). Following sequencing, nucleotide sequences were annotated and 894 bp were compared phylogenetically with those from strains previously reported in the Sudan and the virus strains published on the GenBank. It could be demonstrated that TY-1/90 and DIK-90 strains belong to the genotype VI of NDV and are in close genetic relationship to sub- genotype VIb...
2016: Open veterinary journal
https://www.readbyqxmd.com/read/27366765/association-of-tomato-leaf-curl-sudan-virus-with-leaf-curl-disease-of-tomato-in-jeddah-saudi-arabia
#15
Sayed Sartaj Sohrab, Muhammad Yasir, Sherif Ali El-Kafrawy, Ayman T Abbas, Magdi Ali Ahmed Mousa, Ahmed A Bakhashwain
Tomato is an important vegetable crop and its production is adversely affected by leaf curl disease caused by begomovirus. Leaf curl disease is a serious concern for tomato crops caused by begomovirus in Jeddah, Kingdom of Saudi Arabia. Tomato leaf curl disease has been shown to be mainly caused either by tomato leaf curl Sudan virus or tomato yellow leaf curl virus as well as tomato leaf curl Oman virus. Many tomato plants infected with monopartite begomoviruses were also found to harbor a symptom enhancing betasatellites...
June 2016: Virusdisease
https://www.readbyqxmd.com/read/27354372/broad-and-temperature-independent-replication-potential-of-filoviruses-on-cells-derived-from-old-and-new-world-bat-species
#16
Megan R Miller, Rebekah J McMinn, Vikram Misra, Tony Schountz, Marcel A Müller, Andreas Kurth, Vincent J Munster
Filoviruses are strongly associated with several species of bats as their natural reservoirs. In this study, we determined the replication potential of all filovirus species: Marburg marburgvirus, Taï Forest ebolavirus, Reston ebolavirus, Sudan ebolavirus, Zaire ebolavirus, and Bundibugyo ebolavirus. Filovirus replication was supported by all cell lines derived from 6 Old and New World bat species: the hammer-headed fruit bat, Buettikofer's epauletted fruit bat, the Egyptian fruit bat, the Jamaican fruit bat, the Mexican free-tailed bat and the big brown bat...
October 15, 2016: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27354371/the-domestic-ferret-mustela-putorius-furo-as-a-lethal-infection-model-for-3-species-of-ebolavirus
#17
Robert W Cross, Chad E Mire, Viktoriya Borisevich, Joan B Geisbert, Karla A Fenton, Thomas W Geisbert
Small-animal models have been developed for several Filoviridae species; however, serial adaptation was required to produce lethal infection. These adapted viruses have sequence changes in several genes, including those that modulate the host immune response. Nonhuman primate models do not require adaptation of filoviruses. Here, we describe lethal models of disease for Bundibugyo, Sudan, and Zaire species of Ebolavirus in the domestic ferret, using wild-type nonadapted viruses. Pathologic features were consistent with disease in primates...
August 15, 2016: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27309050/the-use-of-spatial-and-spatiotemporal-modeling-for-surveillance-of-h5n1-highly-pathogenic-avian-influenza-in-poultry-in-the-middle-east
#18
Mohammad Alkhamis, Robert J Hijmans, Abdullah Al-Enezi, Beatriz Martínez-López, Andres M Perea
Since 2005, H5N1 highly pathogenic avian influenza virus (HPAIV) has severely impacted the economy and public health in the Middle East (ME) with Egypt as the most affected country. Understanding the high-risk areas and spatiotemporal distribution of the H5N1 HPAIV in poultry is prerequisite for establishing risk-based surveillance activities at a regional level in the ME. Here, we aimed to predict the geographic range of H5N1 HPAIV outbreaks in poultry in the ME using a set of environmental variables and to investigate the spatiotemporal clustering of outbreaks in the region...
May 2016: Avian Diseases
https://www.readbyqxmd.com/read/27280232/perception-and-attitude-towards-ebola-virus-disease-among-traditional-healers-in-ibadan-nigeria
#19
K Aminu, A S Jegede
BACKGROUND: Nigeria experienced her first outbreak of Ebola Virus Disease (EVD) in the second-half of 2014. Since its first occurrence in Zaire and Sudan in 1976, most studies on EVD were clinically based and were carried out using biomedical approaches. No empirical social science/behavioural-oriented study exists on the deadly EVD in Nigeria. OBJECTIVE: This study examined the traditional healers' perception and attitude towards Ebola virus disease in Ibadan metropolis...
September 2015: African Journal of Medicine and Medical Sciences
https://www.readbyqxmd.com/read/27268907/neglected-filoviruses
#20
REVIEW
Robin Burk, Laura Bollinger, Joshua C Johnson, Jiro Wada, Sheli R Radoshitzky, Gustavo Palacios, Sina Bavari, Peter B Jahrling, Jens H Kuhn
Eight viruses are currently assigned to the family Filoviridae Marburg virus, Sudan virus and, in particular, Ebola virus have received the most attention both by researchers and the public from 1967 to 2013. During this period, natural human filovirus disease outbreaks occurred sporadically in Equatorial Africa and, despite high case-fatality rates, never included more than several dozen to a few hundred infections per outbreak. Research emphasis shifted almost exclusively to Ebola virus in 2014, when this virus was identified as the cause of an outbreak that has thus far involved more than 28 646 people and caused more than 11 323 deaths in Western Africa...
July 2016: FEMS Microbiology Reviews
keyword
keyword
72253
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"