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prostate cancer diet

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https://www.readbyqxmd.com/read/28977750/data-independent-mass-spectrometry-approach-for-screening-and-identification-of-dna-adducts
#1
Jingshu Guo, Peter W Villalta, Robert J Turesky
Long-term exposures to environmental toxicants and endogenous electrophiles are causative factors for human diseases including cancer. DNA adducts reflect the internal exposure to genotoxicants and can serve as biomarkers for risk assessment. Liquid chromatography-multistage mass spectrometry (LC-MS(n)) is the most common method for biomonitoring DNA adducts, generally targeting single exposures and measuring up to several adducts. However, the data often provide limited evidence for a role of a chemical in the etiology of cancer...
October 18, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28971702/-we-re-just-not-prepared-for-eating-over-our-whole-life-a-mixed-methods-approach-to-understanding-dietary-behaviors-among-longer-term-cancer-survivors
#2
Ann Carroll Klassen, Katherine Clegg Smith, Michelle Shuster, Kisha I Coa, Laura E Caulfield, Kathy J Helzlsouer, Kimberly S Peairs, Lillie D Shockney, Dara Stoney, Susan Hannum
BACKGROUND: In many countries, there are growing numbers of persons living with a prior diagnosis of cancer, due to the aging population and more successful strategies for treatment. There is also growing evidence of the importance of healthful diet and weight management for survivorship, yet many long-term cancer survivors are not successfully following recommendations. METHODS: We explored this issue in a mixed methods study with 53 adult survivors of 3 cancers (breast, prostate, and non-Hodgkin's lymphoma), living in Maryland...
September 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28969358/possible-role-of-diet-in-cancer-systematic-review-and-multiple-meta-analyses-of-dietary-patterns-lifestyle-factors-and-cancer-risk
#3
Giuseppe Grosso, Francesca Bella, Justyna Godos, Salvatore Sciacca, Daniele Del Rio, Sumantra Ray, Fabio Galvano, Edward L Giovannucci
Context: Evidence of an association between dietary patterns derived a posteriori and risk of cancer has not been reviewed comprehensively. Objective: The aim of this review was to investigate the relation between a posteriori-derived dietary patterns, grouped as healthy or unhealthy, and cancer risk. The relation between cancer risk and background characteristics associated with adherence to dietary patterns was also examined. Data Sources: PubMed and Embase electronic databases were searched...
June 1, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/28954418/adherence-to-mediterranean-diet-and-risk-of-cancer-an-updated-systematic-review-and-meta-analysis
#4
REVIEW
Lukas Schwingshackl, Carolina Schwedhelm, Cecilia Galbete, Georg Hoffmann
The aim of the present systematic review and meta-analysis was to gain further insight into the effects of adherence to Mediterranean Diet (MedD) on risk of overall cancer mortality, risk of different types of cancer, and cancer mortality and recurrence risk in cancer survivors. Literature search was performed using the electronic databases PubMed, and Scopus until 25 August 2017. We included randomized trials (RCTs), cohort (for specific tumors only incidence cases were used) studies, and case-control studies...
September 26, 2017: Nutrients
https://www.readbyqxmd.com/read/28944626/caveolin-1-secreted-from-adipose-tissues-and-adipocytes-functions-as-an-adipogenesis-enhancer
#5
Chia-Chu Chang, Chen-Yu Chen, Hui-Chin Wen, Chih-Yang Huang, Ming-Shiu Hung, Hsi-Chi Lu, Woan-Ling Chen, Chung-Ho Chang
OBJECTIVE: Caveolin-1 (Cav-1) is expressed abundantly in adipose tissue and involved in many physiological processes. While Cav-1 has been reported to be secreted in pancreatic acinar cells and LNCaP prostate cancer cells, its secretion from adipose tissue awaits investigation. METHODS: Cav-1 secretion from 3T3-L1 adipocytes and fat tissues from normal chow diet- and high-fat diet (HFD)-fed mice was measured. Functions and uptake of secreted Cav-1 proteins were assessed by adding Cav-1 back to preadipocytes and LNCaP cells...
September 25, 2017: Obesity
https://www.readbyqxmd.com/read/28939770/myristoylation-of-src-kinase-mediates-src-induced-and-high-fat-diet-accelerated-prostate-tumor-progression-in-mice
#6
Sungjin Kim, Xiangkun Yang, Qianjin Li, Meng Wu, Leah Costyn, Zanna Beharry, Michael G Bartlett, Houjian Cai
Exogenous fatty acids provide substrates for energy production and the biogenesis of the cytoplasmic membrane, but they also enhance cellular signaling during cancer cell proliferation. However, it remains controversial whether dietary fatty acids are correlated with tumor progression. In this study, we demonstrate that increased Src kinase activity is associated with high fat diet accelerated progression of prostate tumors and that Src kinases mediate this pathological process. Moreover, in the in vivo prostate regeneration assay, host SCID mice carrying Src(Y529F) transduced regeneration tissues were fed with a low fat diet or a high fat diet and treated with vehicle or dasatinib...
September 22, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28929838/the-influence-of-nutritional-factors-on-prostate-cancer-incidence-and-aggressiveness
#7
Manrique Pascual-Geler, Noelia Urquiza-Salvat, Jose Manuel Cozar, Inmaculada Robles-Fernandez, Ana Rivas, Luis Javier Martinez-Gonzalez, Francisco Manuel Ocaña-Peinado, Jose Antonio Lorente, Maria Jesus Alvarez-Cubero
There is an increasing evidence for a link between nutrition, lifestyle and prostate cancer (PCa) development and/or progression of disease. The objective of this study was to examine the association between dietary factors and PCa incidence and aggressiveness in a case-control study. After the analysis of the anatomic pathology, subjects were classified in patients with PCa (n = 157) and controls (n = 158). Clinical data including Gleason score, PSA values and biopsy results, were compiled. Frequencies of food consumption and sociodemographic data were also obtained...
September 20, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28921841/in-a-randomized-trial-in-prostate-cancer-patients-dietary-protein-restriction-modifies-markers-of-leptin-and-insulin-signaling-in-plasma-extracellular-vesicles
#8
Erez Eitan, Valeria Tosti, Caitlin N Suire, Edda Cava, Sean Berkowitz, Beatrice Bertozzi, Sophia M Raefsky, Nicola Veronese, Ryan Spangler, Francesco Spelta, Maja Mustapic, Dimitrios Kapogiannis, Mark P Mattson, Luigi Fontana
Obesity, metabolic syndrome, and hyperleptinemia are associated with aging and age-associated diseases including prostate cancer. One experimental approach to inhibit tumor growth is to reduce dietary protein intake and hence levels of circulating amino acids. Dietary protein restriction (PR) increases insulin sensitivity and suppresses prostate cancer cell tumor growth in animal models, providing a rationale for clinical trials. We sought to demonstrate that biomarkers derived from plasma extracellular vesicles (EVs) reflect systemic leptin and insulin signaling and respond to dietary interventions...
September 17, 2017: Aging Cell
https://www.readbyqxmd.com/read/28901272/disorders-of-mechanisms-of-calcium-metabolism-control-as-potential-risk-factors-of-prostate-cancer
#9
Dorota Skrajnowska, Barbara Bobrowska-Korczak, Andrzej Tokarz
Prostate cancer significantly affects the overall morbidity and mortality of malignant tumours in highly developed countries. Important risk factors include family predisposition and regional, racial and dietary determinants. The scientific literature contains a great deal of data on the role of calcium and dairy products in general in the process of neoplastic transformation of the prostate. This is most likely linked to the fact that changes in the concentration of calcium ions control such varied life processes as secretion of hormones and neurotransmitters, the level of cyclic nucleotides, and cell growth, division and differentiation...
September 12, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28895922/the-effect-of-nutrition-therapy-and-exercise-on-cancer-related-fatigue-and-quality-of-life-in-men-with-prostate-cancer-a-systematic-review
#10
REVIEW
Brenton J Baguley, Kate A Bolam, Olivia R L Wright, Tina L Skinner
BACKGROUND: Improvements in diet and/or exercise are often advocated during prostate cancer treatment, yet the efficacy of, and optimal nutrition and exercise prescription for managing cancer-related fatigue and quality of life remains elusive. The aim of this study is to systematically review the effects of nutrition and/or exercise on cancer-related fatigue and/or quality of life. METHODS: A literature search was conducted in six electronic databases. The Delphi quality assessment list was used to evaluate the methodological quality of the literature...
September 12, 2017: Nutrients
https://www.readbyqxmd.com/read/28884432/plasma-enterolactone-and-risk-of-prostate-cancer-in-middle-aged-swedish-men
#11
Peter Wallström, Isabel Drake, Emily Sonestedt, Bo Gullberg, Anders Bjartell, Håkan Olsson, Herman Adlercreutz, Matti J Tikkanen, Elisabet Wirfält
PURPOSE: Enterolactone (ENL) is formed in the human gut after consumption of lignans, has estrogenic properties, and has been associated with risk of prostate cancer. We examined the association between plasma ENL levels and prostate cancer in a nested case-control study within the population-based Malmö Diet and Cancer cohort. We also examined the association between plasma ENL and dietary and lifestyle factors. METHODS: The study population consisted of 1010 cases occurring during a mean follow-up of 14...
September 7, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28884114/the-mediterranean-diet-reduces-the-risk-and-mortality-of-the-prostate-cancer-a-narrative-review
#12
REVIEW
Cristiano Capurso, Gianluigi Vendemiale
Prostate cancer is the second most common cancer in the world among men, and is the fifth most common cause of cancer death among men. The aim of our review was to analyze observational and case-control studies to point out the effects of overweight and diets components on the cancer risk, particularly on risk of prostate cancer, and the effect of the Mediterranean diet (MD) on the reduction of risk and mortality of prostate cancer. It is known that incidence and progression of cancer is multifactorial. Cancer of the large bowel, breast, endometrium, and prostate are due also to a high body mass index and to high consumption of high carcinogenic dietary factors, as red and processed meat or saturated fats rich foods, and to a low consumption of vegetables and fruits...
2017: Frontiers in Nutrition
https://www.readbyqxmd.com/read/28863047/aspirin-use-and-mortality-in-two-contemporary-u-s-cohorts
#13
Wen-Yi Huang, Sarah E Daugherty, Meredith S Shiels, Mark P Purdue, Neal D Freedman, Christian C Abnet, Albert R Hollenbeck, Richard B Hayes, Debra T Silverman, Sonja I Berndt
BACKGROUND: Daily aspirin use has been recommended for secondary prevention of cardiovascular disease, but its use for primary prevention remains controversial. METHODS: We followed 440,277 men and women from the NIH-AARP Diet and Health Study (ages 50-71) and the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (ages 55-74) for mortality for 13 years on average. Frequency of aspirin use was ascertained through self-report, and cause of death by death certificates...
August 31, 2017: Epidemiology
https://www.readbyqxmd.com/read/28854891/cancer-related-risk-factors-and-incidence-of-major-cancers-by-race-gender-and-region-analysis-of-the-nih-aarp-diet-and-health-study
#14
Tomi Akinyemiju, Howard Wiener, Maria Pisu
BACKGROUND: Racial disparities in the incidence of major cancers may be attributed to differences in the prevalence of established, modifiable risk factors such as obesity, smoking, physical activity and diet. METHODS: Data from a prospective cohort of 566,398 adults aged 50-71 years, 19,677 African-American and 450,623 Whites, was analyzed. Baseline data on cancer-related risk factors such as smoking, alcohol, physical activity and dietary patterns were used to create an individual adherence score...
August 30, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28842865/leveraging-the-family-influence-of-women-in-prostate-cancer-efforts-targeting-african-american-men
#15
O N Okoro, C A Rutherford, S F Witherspoon
BACKGROUND: Incidence rate of prostate cancer among African American (AA) men is 1.6 times that in White men. Prevention efforts in this population have typically been through faith-based organizations and barber shops, with a few including significant others. Culturally, women are known to have a strong influence in the AA family. The current study assessed prostate cancer knowledge and explored perceptions on the roles of women in prostate cancer prevention. METHODS: To assess prostate cancer knowledge, a 25-item questionnaire was administered to convenience samples of AA women (n = 297) and men (n = 199)...
August 25, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28826375/nature-nurture-and-cancer-risks-genetic-and-nutritional-contributions-to-cancer
#16
REVIEW
Evropi Theodoratou, Maria Timofeeva, Xue Li, Xiangrui Meng, John P A Ioannidis
It is speculated that genetic variants are associated with differential responses to nutrients (known as gene-diet interactions) and that these variations may be linked to different cancer risks. In this review, we critically evaluate the evidence across 314 meta-analyses of observational studies and randomized controlled trials of dietary risk factors and the five most common cancers (breast, lung, prostate, colorectal, and stomach). We also critically evaluate the evidence across 13 meta-analyses of observational studies of gene-diet interactions for the same cancers...
August 21, 2017: Annual Review of Nutrition
https://www.readbyqxmd.com/read/28826374/coffee-caffeine-and-health-outcomes-an-umbrella-review
#17
REVIEW
Giuseppe Grosso, Justyna Godos, Fabio Galvano, Edward L Giovannucci
To evaluate the associations between coffee and caffeine consumption and various health outcomes, we performed an umbrella review of the evidence from meta-analyses of observational studies and randomized controlled trials (RCTs). Of the 59 unique outcomes examined in the selected 112 meta-analyses of observational studies, coffee was associated with a probable decreased risk of breast, colorectal, colon, endometrial, and prostate cancers; cardiovascular disease and mortality; Parkinson's disease; and type-2 diabetes...
August 21, 2017: Annual Review of Nutrition
https://www.readbyqxmd.com/read/28765837/the-impact-of-finasteride-and-dutasteride-treatments-on-proliferation-apoptosis-androgen-receptor-5%C3%AE-reductase-1-and-5%C3%AE-reductase-2-in-tramp-mouse-prostates
#18
Alexander B Opoku-Acheampong, Jamie N Henningson, Brian L Lindshield
BACKGROUND: Previously, we studied the effect of finasteride- or dutasteride-containing diets in male C57BL/6 TRAMP x FVB mice. Pre (6 weeks of age) and post (12 weeks of age) groups received finasteride or dutasteride to determine the efficacy of these pharmaceuticals on prostate cancer (PCa) development in male C57BL/6 TRAMP x FVB mice. Post-Dutasteride treatment was more effective than Pre-Dutasteride treatment, and dutasteride treatments were more effective than finasteride treatments in decreasing prostatic intraepithelial neoplasia (PIN) progression and PCa development...
July 2017: Heliyon
https://www.readbyqxmd.com/read/28764147/study-of-vitamin-d-receptor-gene-polymorphism-foki-taqi-and-apai-among-prostate-cancer-patients-in-north-india
#19
Pankaj Ramrao Kambale, Deepa Haldar, B C Kabi, Kalpana Pankaj Kambale
INTRODUCTION: Incidence of prostate cancer is rising worldwide. Multiple factors have been suggested for the aetiology of prostate cancer including ethnic, genetic and diet. Vitamin D (calcitriol) has been shown to have role in cell growth and differentiation and its deficiency is implicated as one of the aetiological factors in prostate cancer. Prostatic epithelial cells express Vitamin D Receptor (VDR) as well as 1α- hydroxylase enzyme that are required for the synthesis of calcitriol and its action...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28753805/the-urinary-tract-microbiome-in-health-and-disease
#20
REVIEW
Isabel M Aragón, Bernardo Herrera-Imbroda, María I Queipo-Ortuño, Elisabeth Castillo, Julia Sequeira-García Del Moral, Jaime Gómez-Millán, Gozde Yucel, María F Lara
CONTEXT: The urinary tract, previously considered a sterile body niche, has emerged as the host of an array of bacteria in healthy individuals, revolutionizing the urology research field. OBJECTIVE: To review the literature on microbiome implications in the urinary tract and the usefulness of probiotics/prebiotics and diet as treatment for urologic disorders. EVIDENCE ACQUISITION: A systematic review was conducted using PubMed and Medline from inception until July 2016...
November 14, 2016: European Urology Focus
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