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prostate cancer diet

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https://www.readbyqxmd.com/read/29219783/diet-and-other-lifestyle-factors-associated-with-prostate-cancer-differ-between-the-german-and-italian-region-of-switzerland
#1
Aline Richard, David Faeh, Matthias Bopp, Sabine Rohrmann
PURPOSE: In Switzerland, prostate cancer mortality is higher in the German than in the Italian-speaking region. We aimed at exploring the association of living in one of the two regions with lifestyle factors presumably lowering the risk of prostate cancer. METHODS: We pooled data from the Swiss Health Survey, conducted every 5 years 1992 - 2012. Information on diet (meat, fish, dairy, fruits and vegetables), alcohol, smoking, physical activity and body mass index were dichotomized into "risky" and "risk-reducing" lifestyle behaviour with respect to prostate cancer...
December 8, 2017: International Journal for Vitamin and Nutrition Research. Journal International de Vitaminologie et de Nutrition
https://www.readbyqxmd.com/read/29217211/mediating-effects-of-cancer-risk-factors-on-the-association-between-race-and-cancer-incidence-analysis-of-the-nih-aarp-diet-and-health-study
#2
Tomi Akinyemiju, Justin Xavier Moore, Maria Pisu
PURPOSE: Racial disparities exist in the prevalence of cancer-related risk factors and incidence of cancer. The objective of this study is to determine if cancer-related risk factors mediate the association between race and cancer incidence. METHODS: We performed prospective analysis of data from the National Institutes of Health-American Association of Retired Persons Diet and Health Study, years 1995 through 2011. We compared differences in baseline characteristics between black and white participants using χ2 tests and Wilcoxon tests, as appropriate...
November 23, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/29210648/vitamins-for-cancer-prevention-and-treatment-an-insight
#3
A Jain, A Tiwari, A Verma, S K Jain
Over a few decades a strong interlink between oxidative damage and cancer has been investigated by various scientists across the world on the basis of epidemiological observations of the effects of fruits and vegetables used in the diet for cancer patients. Primarily, Vitamin C, Vitamin D and Vitamin E are reported to be involved in the amelioration of side effects which occur in chemotherapy and radiation therapy of lungs, stomach, prostate, colorectal, gastric head and neck cancers. The vitamins acting as antioxidant adjuvants are found to have apoptotic and anti-angiogenesis potential as well as inhibitory effects against metastasis in cancer cells...
December 4, 2017: Current Molecular Medicine
https://www.readbyqxmd.com/read/29202102/combinatorial-treatment-with-natural-compounds-in-prostate-cancer-inhibits-prostate-tumor-growth-and-leads-to-key-modulations-of-cancer-cell-metabolism
#4
Alessia Lodi, Achinto Saha, Xiyuan Lu, Bo Wang, Enrique Sentandreu, Meghan Collins, Mikhail G Kolonin, John DiGiovanni, Stefano Tiziani
High-throughput screening of a natural compound library was performed to identify the most efficacious combinatorial treatment on prostate cancer. Ursolic acid, curcumin and resveratrol were selected for further analyses and administered in vivo via the diet, either alone or in combination, in a mouse allograft model of prostate cancer. All possible combinations of these natural compounds produced synergistic effects on tumor size and weight, as predicted in the screens. A subsequent untargeted metabolomics and metabolic flux analysis using isotopically labeled glutamine indicated that the compound combinations modulated glutamine metabolism...
2017: NPJ Precision Oncology
https://www.readbyqxmd.com/read/29194691/mediterranean-diet-after-prostate-cancer-diagnosis-and-urinary-and-sexual-functioning-the-health-professionals-follow-up-study
#5
Scott R Bauer, Erin L Van Blarigan, Meir J Stampfer, June M Chan, Stacey A Kenfield
BACKGROUND: Men with prostate cancer often experience urinary and sexual dysfunction after treatment. Previous studies have demonstrated a relationship between dietary factors and these symptoms among men with diabetes or metabolic syndrome. However, there are limited data on whether diet after prostate cancer diagnosis, including a Mediterranean dietary pattern, affects urinary and sexual function among prostate cancer survivors. METHODS: Men diagnosed with non-metastatic prostate cancer in the Health Professionals Follow-up Study (n = 2960) from 1986 to 2012 were prospectively followed for a median of 8...
December 1, 2017: Prostate
https://www.readbyqxmd.com/read/29154974/prostate-cancer-health-disparities-an-immuno-biological-perspective
#6
Sanjay Kumar, Rajesh Singh, Shalie Malik, Upender Manne, Manoj Mishra
Prostate cancer (PCa) is the most commonly diagnosed malignancy in males, and, in the United States, is the second leading cause of cancer-related death for men older than 40 years. There is a higher incidence of PCa for African Americans (AAs) than for European-Americans (EAs). Investigations related to the incidence of PCa-related health disparities for AAs suggest that there are differences in the genetic makeup of these populations. Other differences are environmentally induced (e.g., diet and lifestyle), and the exposures are different...
November 15, 2017: Cancer Letters
https://www.readbyqxmd.com/read/29148069/long-term-oral-exposure-to-safe-dose-of-bisphenol-a-in-association-with-high-fat-diet-stimulate-the-prostatic-lesions-in-a-rodent-model-for-prostate-cancer
#7
Camila H Facina, Silvana G P Campos, Bianca F Gonçalves, Rejane M Góes, Patricia S L Vilamaior, Sebastião R Taboga
BACKGROUND: Studies have shown that exposure to environmental chemicals known as endocrine disruptors can cause permanent changes in genital organs, such as the prostate. Among these environmental chemicals stands out bisphenol A (BPA). Another factor associated with prostate changes is the consumption of a high-fat diet. Although the relationship between the consumption of a high-fat diet and an increased risk of prostate cancer is well established, the mechanisms that lead to the establishment of this disease are not completely understood, nor the simultaneous action of BPA and high-fat diet...
November 17, 2017: Prostate
https://www.readbyqxmd.com/read/29137948/analysis-of-tumor-biology-to-advance-cancer-health-disparity-research
#8
REVIEW
Cheryl Jacobs Smith, Tsion Zewdu Minas, Stefan Ambs
Cancer mortality rates in the US continue to decline. Reductions in tobacco use, uptake of preventive measures, adoption of early detection methods, and better treatments have resulted in improved cancer outcomes for men and women. Despite this progress, some population groups continue to experience an excessive cancer burden when compared with other population groups. One of the most prominent cancer health disparities exists in prostate cancer. Prostate cancer mortality rates are highest among men of African ancestry when compared with other men, both in the US and globally...
November 11, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/29124044/index-based-dietary-patterns-and-the-risk-of-prostate-cancer
#9
REVIEW
Ji Hyun Kim, Jeongseon Kim
Prostate cancer is the second leading cause for cancer incidence in male. Although this high incidence is due to prostate specific antigen screening, other risk-factors, such as diet, might also be involved. The results of previous studies on the association between prostate cancer risk and individual dietary components have been conflicting. Thus, evaluation by dietary pattern analysis rather than individual dietary factors is suggested. The purpose of this study was to review the association of prostate cancer with a priori dietary indices, which are less studied and reviewed to date compared to a posteriori indices...
October 2017: Clinical Nutrition Research
https://www.readbyqxmd.com/read/29121168/%C3%AE-tocopherol-inhibits-the-development-of-prostate-adenocarcinoma-in-prostate-specific-pten-mice
#10
Hong Wang, Xu Yang, Anna Liu, Guocan Wang, Maarten C Bosland, Chung S Yang
The PTEN/PI3K/AKT axis plays a critical role in regulating cell growth, differentiation and survival. Activation of this signaling pathway is frequently found in human cancers. Our previous studies demonstrated that δ-tocopherol (δ-T) attenuates the activation of AKT by growth factor in prostate cancer cell lines, leading to inhibition of proliferation and induction of apoptosis. Herein, we investigated whether δ-T inhibits the development of prostate adenocarcinoma in prostate-specific Pten-/- (Ptenp-/-) mice in which the activation of AKT is the major driving force for tumorigenesis...
November 7, 2017: Carcinogenesis
https://www.readbyqxmd.com/read/29080344/bile-acids-and-cancer-direct-and-environmental-dependent-effects
#11
Agostino Di Ciaula, David Q-H Wang, Emilio Molina-Molina, Raquel Lunardi Baccetto, Giuseppe Calamita, Vincenzo O Palmieri, Piero Portincasa
Bile acids (BAs) regulate the absorption of fat-soluble vitamins, cholesterol and lipids but have also a key role as singalling molecules and in the modulation of epithelial cell proliferation, gene expression and metabolism. These homeostatic pathways, when disrupted, are able to promote local inflammation, systemic metabolic disorders and, ultimately, cancer. The effect of hydrophobic BAs, in particular, can be linked with cancer in several digestive (mainly oesophagus, stomach, liver, pancreas, biliary tract, colon) and extra-digestive organs (i...
October 28, 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/29074535/flaxseed-consumption-inhibits-chemically-induced-lung-tumorigenesis-and-modulates-expression-of-phase-ii-enzymes-and-inflammatory-cytokines-in-a-j-mice
#12
Shireen Chikara, Sujan Mamidi, Avinash Sreedasyam, Kishore Chittem, Ralph Pietrofesa, Athena Zuppa, Ganesh Moorthy, Neil Dyer, Melpo Christofidou-Solomidou, Katie M Reindl
Flaxseed consumption is associated with reduced oxidative stress and inflammation in lung injury models, and has shown anti-cancer effects for breast and prostate tissues. However, the chemopreventive potential of flaxseed remains unexplored for lung cancer. In this study, we investigated the effect of flaxseed on tobacco smoke carcinogen (NNK)-induced lung tumorigenesis in an A/J mouse model. Mice exposed to NNK were fed a control diet or a 10% flaxseed-supplemented diet for 26 weeks. Flaxseed-fed mice showed reduced lung tumor incidence (78%) and multiplicity, with an average of 2...
October 26, 2017: Cancer Prevention Research
https://www.readbyqxmd.com/read/29065504/a-mini-review-of-reactive-oxygen-species-in-urological-cancer-correlation-with-nadph-oxidases-angiogenesis-and-apoptosis
#13
REVIEW
Yasuyoshi Miyata, Tomohiro Matsuo, Yuji Sagara, Kojiro Ohba, Kaname Ohyama, Hideki Sakai
Oxidative stress refers to elevated reactive oxygen species (ROS) levels, and NADPH oxidases (NOXs), which are one of the most important sources of ROS. Oxidative stress plays important roles in the etiologies, pathological mechanisms, and treatment strategies of vascular diseases. Additionally, oxidative stress affects mechanisms of carcinogenesis, tumor growth, and prognosis in malignancies. Nearly all solid tumors show stimulation of neo-vascularity, termed angiogenesis, which is closely associated with malignant aggressiveness...
October 22, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29052905/metabolic-changes-in-patients-with-prostate-cancer-during-androgen-deprivation-therapy
#14
REVIEW
Koji Mitsuzuka, Yoichi Arai
Androgen deprivation therapy continues to be widely used for the treatment of prostate cancer despite the appearance of new-generation androgen-receptor targeting drugs after 2000. Androgen deprivation therapy can alleviate symptoms in patients with metastatic prostate cancer and might have a survival benefit in some patients, but it causes undesirable changes in lipid, glucose, muscle or bone metabolism. These metabolic changes could lead to new onset or worsening of diseases, such as obesity, metabolic syndrome, diabetes mellitus, cardiovascular disease, sarcopenia or fracture...
October 20, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29049045/nutrition-physical-activity-and-lifestyle-factors-in-prostate-cancer-prevention
#15
Eric Ballon-Landa, John Kellogg Parsons
PURPOSE OF REVIEW: To review current evidence for prostate cancer prevention with nutrition, physical activity, and lifestyle interventions and identify future research directions. RECENT FINDINGS: Multiple preclinical and observational studies have observed that diet, exercise, and lifestyle interventions may play a role in mitigating disease progression, mortality, and overall disease burden for high-grade and fatal prostate cancer. Increased vegetable and fruit intakes, decreased red meat and saturated fat intakes, and increased exercise are potentially associated with decreased risk of incident disease and increased progression-free, prostate cancer-specific, and overall survival...
October 18, 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/29038181/barriers-and-facilitators-to-healthy-lifestyle-and-acceptability-of-a-dietary-and-physical-activity-intervention-among-african-caribbean-prostate-cancer-survivors-in-the-uk-a-qualitative-study
#16
Vanessa Er, J Athene Lane, Richard M Martin, Raj Persad, Frank Chinegwundoh, Victoria Njoku, Eileen Sutton
OBJECTIVES: Diet and lifestyle may have a role in delaying prostate cancer progression, but little is known about the health behaviours of Black British prostate cancer survivors despite this group having a higher prostate cancer mortality rate than their White counterparts. We explored the barriers and facilitators to dietary and lifestyle changes and the acceptability of a diet and physical activity intervention in African Caribbean prostate cancer survivors. DESIGN: We conducted semistructured in-depth interviews and used thematic analysis to code and group the data...
October 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28977750/data-independent-mass-spectrometry-approach-for-screening-and-identification-of-dna-adducts
#17
Jingshu Guo, Peter W Villalta, Robert J Turesky
Long-term exposures to environmental toxicants and endogenous electrophiles are causative factors for human diseases including cancer. DNA adducts reflect the internal exposure to genotoxicants and can serve as biomarkers for risk assessment. Liquid chromatography-multistage mass spectrometry (LC-MS(n)) is the most common method for biomonitoring DNA adducts, generally targeting single exposures and measuring up to several adducts. However, the data often provide limited evidence for a role of a chemical in the etiology of cancer...
November 7, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28971702/-we-re-just-not-prepared-for-eating-over-our-whole-life-a-mixed-methods-approach-to-understanding-dietary-behaviors-among-longer-term-cancer-survivors
#18
Ann Carroll Klassen, Katherine Clegg Smith, Michelle Shuster, Kisha I Coa, Laura E Caulfield, Kathy J Helzlsouer, Kimberly S Peairs, Lillie D Shockney, Dara Stoney, Susan Hannum
BACKGROUND: In many countries, there are growing numbers of persons living with a prior diagnosis of cancer, due to the aging population and more successful strategies for treatment. There is also growing evidence of the importance of healthful diet and weight management for survivorship, yet many long-term cancer survivors are not successfully following recommendations. METHODS: We explored this issue in a mixed methods study with 53 adult survivors of 3 cancers (breast, prostate, and non-Hodgkin's lymphoma), living in Maryland...
September 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28969358/possible-role-of-diet-in-cancer-systematic-review-and-multiple-meta-analyses-of-dietary-patterns-lifestyle-factors-and-cancer-risk
#19
Giuseppe Grosso, Francesca Bella, Justyna Godos, Salvatore Sciacca, Daniele Del Rio, Sumantra Ray, Fabio Galvano, Edward L Giovannucci
Context: Evidence of an association between dietary patterns derived a posteriori and risk of cancer has not been reviewed comprehensively. Objective: The aim of this review was to investigate the relation between a posteriori-derived dietary patterns, grouped as healthy or unhealthy, and cancer risk. The relation between cancer risk and background characteristics associated with adherence to dietary patterns was also examined. Data Sources: PubMed and Embase electronic databases were searched...
June 1, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/28954418/adherence-to-mediterranean-diet-and-risk-of-cancer-an-updated-systematic-review-and-meta-analysis
#20
REVIEW
Lukas Schwingshackl, Carolina Schwedhelm, Cecilia Galbete, Georg Hoffmann
The aim of the present systematic review and meta-analysis was to gain further insight into the effects of adherence to Mediterranean Diet (MedD) on risk of overall cancer mortality, risk of different types of cancer, and cancer mortality and recurrence risk in cancer survivors. Literature search was performed using the electronic databases PubMed, and Scopus until 25 August 2017. We included randomized trials (RCTs), cohort (for specific tumors only incidence cases were used) studies, and case-control studies...
September 26, 2017: Nutrients
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