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prostate cancer diet

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https://www.readbyqxmd.com/read/29451459/apiaceous-vegetables-and-cruciferous-phytochemicals-reduced-phip-dna-adducts-in-prostate-but-not-in-pancreas-of-wistar-rats
#1
Jae Kyeom Kim, Marissa A McCormick, Cynthia M Gallaher, Daniel D Gallaher, Sabrina P Trudo
We previously showed rats fed with apiaceous vegetables, but not with their putative chemopreventive phytochemicals, reduced colonic DNA adducts formed by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), a dietary procarcinogen. We report here the effects of feeding apiaceous and cruciferous vegetables versus their purified predominant phytochemicals, either alone or combined, on prostate and pancreatic PhIP-DNA adduct formation. In experiment I, male Wistar rats received three supplemented diets: CRU (cruciferous vegetables), API (apiaceous vegetables), and CRU+API (both types of vegetables)...
February 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29444771/consumption-of-ultra-processed-foods-and-cancer-risk-results-from-nutrinet-sant%C3%A3-prospective-cohort
#2
Thibault Fiolet, Bernard Srour, Laury Sellem, Emmanuelle Kesse-Guyot, Benjamin Allès, Caroline Méjean, Mélanie Deschasaux, Philippine Fassier, Paule Latino-Martel, Marie Beslay, Serge Hercberg, Céline Lavalette, Carlos A Monteiro, Chantal Julia, Mathilde Touvier
OBJECTIVE: To assess the prospective associations between consumption of ultra-processed food and risk of cancer. DESIGN: Population based cohort study. SETTING AND PARTICIPANTS: 104 980 participants aged at least 18 years (median age 42.8 years) from the French NutriNet-Santé cohort (2009-17). Dietary intakes were collected using repeated 24 hour dietary records, designed to register participants' usual consumption for 3300 different food items...
February 14, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29444163/the-effect-of-nutramiltm-complex-food-for-special-medical-purpose-on-breast-and-prostate-carcinoma-cells
#3
Aneta A Koronowicz, Mariola Drozdowska, Barbara Wielgos, Ewelina Piasna-Słupecka, Dominik Domagała, Joanna Dulińska-Litewka, Teresa Leszczyńska
NutramilTM Complex is a multicomponent food product that meets the requirements of a food for special medical purpose. As a complete, high-energy diet it consists of properly balanced nutrients, vitamins and minerals. The aim of this study was to assess the effect of NutramilTM Complex on breast and prostate carcinoma cells. Our results showed that NutramilTM Complex reduced the viability and proliferation of breast and prostate cancer cells and that this process was associated with the induction of apoptosis via activation of caspase signalling...
2018: PloS One
https://www.readbyqxmd.com/read/29434856/high-fat-diet-induced-adipokine-and-cytokine-alterations-promote-the-progression-of-prostate-cancer-in-vivo-and-in-vitro
#4
Meng-Bo Hu, Hua Xu, Wen-Hui Zhu, Pei-De Bai, Ji-Meng Hu, Tian Yang, Hao-Wen Jiang, Qiang Ding
High-fat diet (HFD) -induced obesity is associated with more aggressive and lethal prostate cancer (PCa) in males, although the exact underlying mechanisms remain unclear. In the present study, transgenic adenocarcinoma of mouse prostate (TRAMP) models fed on an HFD (40% fat) or a control diet (CD; 16% fat) were generated, and cancer differentiation, local invasion and metastasis were compared at 20, 24 and 28 weeks. Mouse sera from each group were collected, and adipokines and cytokines were measured using multiplex immunoassays...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29434658/healthy-living-and-cancer-evidence-from-uk-biobank
#5
Peter C Elwood, Alex Whitmarsh, John Gallacher, Anthony Bayer, Richard Adams, Luke Heslop, Janet Pickering, Gareth Morgan, Julieta Galante, Sunil Dolwani, Marcus Longley, Zoe E Roberts
Context: UK Biobank is a prospective study of half a million subjects, almost all aged 40-69 years, identified in 22 centres across the UK during 2006-2010. Objective: A healthy lifestyle has been described as 'better than any pill, and no side effects [5]. We therefore examined the relationships between healthy behaviours: low alcohol intake, non-smoking, healthy BMI, physical activity and a healthy diet, and the risk of all cancers, colon, breast and prostate cancers in a large dataset...
2018: Ecancermedicalscience
https://www.readbyqxmd.com/read/29426230/lifestyle-and-dietary-factors-and-prostate-cancer-risk-a-multicentre-case-control-study
#6
Mohammad Al Qadire, Murad Alkhalaileh, Mohammed ALBashtawy
This study aims to explore the association between fruit and vegetable intake, high fat, body mass index (BMI) score, physical activity, and the occurrence of prostate cancer among Jordanian men. A case-control study was conducted in three large referral hospitals. The sample included 165 prostate cancer patients in the case group and 177 healthy participants in the control group. The results showed that smoking (odds ratio [OR] = 0.32; 95% confidence interval [CI] = [0.18, 0.57]), a history of prostate infection (OR = 0...
February 1, 2018: Clinical Nursing Research
https://www.readbyqxmd.com/read/29416709/low-dose-statin-treatment-increases-prostate-cancer-aggressiveness
#7
Alfredo Caro-Maldonado, Laura Camacho, Amaia Zabala-Letona, Verónica Torrano, Sonia Fernández-Ruiz, Kepa Zamacola-Bascaran, Leire Arreal, Lorea Valcárcel-Jiménez, Natalia Martín-Martín, Juana M Flores, Ana R Cortazar, Patricia Zúñiga-García, Amaia Arruabarrena-Aristorena, Fabienne Guillaumond, Diana Cabrera, Juan M Falcón-Perez, Ana M Aransay, Antonio Gomez-Muñoz, Mireia Olivan, Juan Morote, Arkaitz Carracedo
Prostate cancer is diagnosed late in life, when co-morbidities are frequent. Among them, hypertension, hypercholesterolemia, diabetes or metabolic syndrome exhibit an elevated incidence. In turn, prostate cancer patients frequently undergo chronic pharmacological treatments that could alter disease initiation, progression and therapy response. Here we show that treatment with anti-cholesterolemic drugs, statins, at doses achieved in patients, enhance the pro-tumorigenic activity of obesogenic diets. In addition, the use of a mouse model of prostate cancer and human prostate cancer xenografts revealed that in vivo simvastatin administration alone increases prostate cancer aggressiveness...
January 5, 2018: Oncotarget
https://www.readbyqxmd.com/read/29376219/selenium-for-preventing-cancer
#8
REVIEW
Marco Vinceti, Tommaso Filippini, Cinzia Del Giovane, Gabriele Dennert, Marcel Zwahlen, Maree Brinkman, Maurice Pa Zeegers, Markus Horneber, Roberto D'Amico, Catherine M Crespi
BACKGROUND: This review is the third update of the Cochrane review "Selenium for preventing cancer". Selenium is a naturally occurring element with both nutritional and toxicological properties. Higher selenium exposure and selenium supplements have been suggested to protect against several types of cancer. OBJECTIVES: To gather and present evidence needed to address two research questions:1. What is the aetiological relationship between selenium exposure and cancer risk in humans?2...
January 29, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29375002/bioactive-compounds-of-the-mediterranean-diet-and-prostate-cancer
#9
Olga López-Guarnido, Noelia Urquiza-Salvat, Maria Saiz, David Lozano-Paniagua, Lourdes Rodrigo, Manrique Pascual-Geler, Jose Antonio Lorente, Maria Jesus Alvarez-Cubero, Ana Rivas
OBJECTIVE: The purpose of this review is to examine the evidence on the effects of bioactive constituents of the Mediterranean diet (MeDi) on prostate cancer (PCa) risk. METHODS: The search for articles came from extensive research in the following databases: PubMed, Scopus, and Web of Science. We used the search terms "Mediterranean diet," "lycopene," "vitamin E," "vitamin C," "Selenium," "resveratrol," "prostate cancer," and combinations, such as "lycopene and prostate cancer" or "resveratrol and prostate cancer...
January 27, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29371140/the-relationship-between-shift-work-and-men-s-health
#10
REVIEW
Nanfu Deng, Taylor P Kohn, Larry I Lipshultz, Alexander W Pastuszak
BACKGROUND: More than 21 million Americans and nearly 20% of the U.S. workforce are shift workers. Non-standard shift work, defined as work that falls outside of 6 am-6 pm, can lead to poor diet, exercise, and sleep habits that lead to decreased productivity, increased workplace accidents, and a variety of negative health outcomes. AIM: To investigate the associations between shift work exposure and chronic medical conditions such as metabolic syndromes, cardiovascular disease, gastrointestinal disturbances, and depression as well as urologic complications including hypogonadism, male infertility, lower urinary tract symptoms, and prostate cancer with a focus on the effects of shift work sleep disorder (SWSD) on the severity of these negative health outcomes...
January 19, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29370858/chronic-diseases-inflammation-and-spices-how-are-they-linked
#11
REVIEW
Ajaikumar B Kunnumakkara, Bethsebie L Sailo, Kishore Banik, Choudhary Harsha, Sahdeo Prasad, Subash Chandra Gupta, Alok Chandra Bharti, Bharat B Aggarwal
Extensive research within the last several decades has revealed that the major risk factors for most chronic diseases are infections, obesity, alcohol, tobacco, radiation, environmental pollutants, and diet. It is now well established that these factors induce chronic diseases through induction of inflammation. However, inflammation could be either acute or chronic. Acute inflammation persists for a short duration and is the host defense against infections and allergens, whereas the chronic inflammation persists for a long time and leads to many chronic diseases including cancer, cardiovascular diseases, neurodegenerative diseases, respiratory diseases, etc...
January 25, 2018: Journal of Translational Medicine
https://www.readbyqxmd.com/read/29364159/elucidating-the-role-of-cd84-and-ahr-in-modulation-of-lps-induced-cytokines-production-by-cruciferous-vegetable-derived-compounds-indole-3-carbinol-and-3-3-diindolylmethane
#12
Thomas T Y Wang, Quynhchi Pham, Young S Kim
Modulation of the immune system by cancer protective food bioactives has preventive and therapeutic importance in prostate cancer, but the mechanisms remain largely unclear. The current study tests the hypothesis that the diet-derived cancer protective compounds, indole-3-carbinol (I3C) and 3,3'-diindolylmethane (DIM), affect the tumor microenvironment by regulation of inflammatory responses in monocytes and macrophages. We also ask whether I3C and DIM act through the aryl hydrocarbon (AHR)-dependent pathway or the signaling lymphocyte activation molecule (SLAM) family protein CD84-mediated pathway...
January 24, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29360138/interventions-to-reduce-acute-and-late-adverse-gastrointestinal-effects-of-pelvic-radiotherapy-for-primary-pelvic-cancers
#13
REVIEW
Theresa A Lawrie, John T Green, Mark Beresford, Linda Wedlake, Sorrel Burden, Susan E Davidson, Simon Lal, Caroline C Henson, H Jervoise N Andreyev
BACKGROUND: An increasing number of people survive cancer but a significant proportion have gastrointestinal side effects as a result of radiotherapy (RT), which impairs their quality of life (QoL). OBJECTIVES: To determine which prophylactic interventions reduce the incidence, severity or both of adverse gastrointestinal effects among adults receiving radiotherapy to treat primary pelvic cancers. SEARCH METHODS: We conducted searches of CENTRAL, MEDLINE, and Embase in September 2016 and updated them on 2 November 2017...
January 23, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29355939/inflammatory-potential-of-diet-and-risk-of-pancreatic-cancer-in-the-prostate-lung-colorectal-and-ovarian-plco-cancer-screening-trial
#14
Jiali Zheng, Anwar T Merchant, Michael D Wirth, Jiajia Zhang, Samuel O Antwi, Azza Shoaibi, Nitin Shivappa, Rachael Z Stolzenberg-Solomon, James R Hebert, Susan E Steck
Inflammation plays a central role in pancreatic cancer etiology and can be modulated by diet. We aimed to examine the association between the inflammatory potential of diet, assessed with the Dietary Inflammatory Index (DII®), and pancreatic cancer risk in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial prospective cohort. Our study included 101,449 participants aged 52 to 78 years at baseline who completed both baseline questionnaire and a diet history questionnaire. Energy-adjusted DII (E-DII) scores were computed based on food and supplement intake...
January 22, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29340091/fatty-acid-binding-protein-4-enhances-prostate-cancer-progression-by-upregulating-matrix-metalloproteinases-and-stromal-cell-cytokine-production
#15
Mingguo Huang, Shintaro Narita, Takamitsu Inoue, Atsushi Koizumi, Mitsuru Saito, Hiroshi Tsuruta, Kazuyuki Numakura, Shigeru Satoh, Hiroshi Nanjo, Takehiko Sasaki, Tomonori Habuchi
Fatty acid binding protein 4 (FABP4) is an abundant protein in adipocytes, and its production is influenced by high-fat diet (HFD) or obesity. The prostate stromal microenvironment induces proinflammatory cytokine production, which is key for the development and progression of prostate cancer (PCa). Here, we show that high FABP4 expression and its secretion by PCa cells directly stimulated PCa cell invasiveness by upregulating matrix metalloproteinases through phosphatidylinositol 3-kinase and mitogen-activated protein kinase signaling pathways...
December 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29335545/an-aberrant-srebp-dependent-lipogenic-program-promotes-metastatic-prostate-cancer
#16
Ming Chen, Jiangwen Zhang, Katia Sampieri, John G Clohessy, Lourdes Mendez, Enrique Gonzalez-Billalabeitia, Xue-Song Liu, Yu-Ru Lee, Jacqueline Fung, Jesse M Katon, Archita Venugopal Menon, Kaitlyn A Webster, Christopher Ng, Maria Dilia Palumbieri, Moussa S Diolombi, Susanne B Breitkopf, Julie Teruya-Feldstein, Sabina Signoretti, Roderick T Bronson, John M Asara, Mireia Castillo-Martin, Carlos Cordon-Cardo, Pier Paolo Pandolfi
Lipids, either endogenously synthesized or exogenous, have been linked to human cancer. Here we found that PML is frequently co-deleted with PTEN in metastatic human prostate cancer (CaP). We demonstrated that conditional inactivation of Pml in the mouse prostate morphs indolent Pten-null tumors into lethal metastatic disease. We identified MAPK reactivation, subsequent hyperactivation of an aberrant SREBP prometastatic lipogenic program, and a distinctive lipidomic profile as key characteristic features of metastatic Pml and Pten double-null CaP...
January 15, 2018: Nature Genetics
https://www.readbyqxmd.com/read/29324670/dietary-carotenoid-intakes-and-prostate-cancer-risk-a-case-control-study-from-vietnam
#17
Dong Van Hoang, Ngoc Minh Pham, Andy H Lee, Duong Nhu Tran, Colin W Binns
The incidence of prostate cancer has increased in Vietnam, but there have been few studies of the risk factors associated with this change. This retrospective case-control study investigated the relation of the intake of carotenoids and their food sources to prostate cancer risk. A sample of 652 participants (244 incident prostate cancer patients, aged 64-75 years, and 408 age frequency-matched controls) were recruited in Ho Chi Minh City during 2013-2015. The habitual diet was ascertained with a validated food-frequency questionnaire, and other factors including demographic and lifestyle characteristics were assessed via face-to-face interviews by trained nurses...
January 11, 2018: Nutrients
https://www.readbyqxmd.com/read/29300347/soy-consumption-and-the-risk-of-prostate-cancer-an-updated-systematic-review-and-meta-analysis
#18
REVIEW
Catherine C Applegate, Joe L Rowles, Katherine M Ranard, Sookyoung Jeon, John W Erdman
Prostate cancer (PCa) is the second most commonly diagnosed cancer in men, accounting for 15% of all cancers in men worldwide. Asian populations consume soy foods as part of a regular diet, which may contribute to the lower PCa incidence observed in these countries. This meta-analysis provides a comprehensive updated analysis that builds on previously published meta-analyses, demonstrating that soy foods and their isoflavones (genistein and daidzein) are associated with a lower risk of prostate carcinogenesis...
January 4, 2018: Nutrients
https://www.readbyqxmd.com/read/29284719/cross-sectional-analyses-of-participation-in-cancer-screening-and-use-of-hormone-replacement-therapy-and-medications-in-meat-eaters-and-vegetarians-the-epic-oxford-study
#19
Tammy Y N Tong, Paul N Appleby, Kathryn E Bradbury, Timothy J Key
OBJECTIVES: To examine differences in health-related behaviours such as screening or testing for cancer, use of hormone replacement therapy (HRT) and use of other medications in different diet groups. DESIGN: We studied 31 260 participants across four diet groups (18 155 meat eaters, 5012 fish eaters, 7179 vegetarians, 914 vegans) in the UK EPIC-Oxford cohort. Information was collected in 5-year (around 2000-2003) or 10-year (around 2007) follow-up questionnaires regarding participation in breast screening, cervical screening, prostate-specific antigen (PSA) testing, use of HRT and use of medications for the past 4 weeks...
December 27, 2017: BMJ Open
https://www.readbyqxmd.com/read/29280253/association-between-dietary-pattern-scores-and-the-prevalence-of-colorectal-adenoma-considering-population-subgroups
#20
Alyson Haslam, Sara Wagner Robb, James R Hébert, Hanwen Huang, Mark H Ebell
AIM: The purpose of the current study is to examine the dietary patterns in a diverse cohort of individuals and to see if the identified dietary patterns predict the prevalence of adenoma in a cross-sectional study. METHODS: Factor analysis was used to derive both sex- and population subgroup-specific dietary patterns among participants in the screening arm of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Logistic regression was used to assess associations between identified factor scores and colorectal adenoma (CRA) in sex-specific subgroups...
December 26, 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
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