Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#21
Nikola Bulj, Vedran Tomasic, Maja Cigrovski Berkovic
BACKGROUND: Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are rare tumors, often diagnosed in an advanced stage when curative treatment is impossible and grueling symptoms related to vasoactive substance release by tumor cells affect patients' quality of life. Cardiovascular complications of GEP-NENs, primarily tricuspid and pulmonary valve disease, and right-sided heart failure, are the leading cause of death, even compared to metastatic disease. CASE SUMMARY: We present a case of a 35-year-old patient with progressive dyspnea, back pain, polyneuropathic leg pain, and nocturnal diarrhea lasting for a decade before the diagnosis of neuroendocrine carcinoma of unknown primary with extensive liver metastases...
March 15, 2024: World Journal of Gastrointestinal Oncology
#22
JOURNAL ARTICLE
Paul Köhli, Lukas Schönnagel, Jan Hambrecht, Jiaqi Zhu, Erika Chiapparelli, Ali E Güven, Gisberto Evangelisti, Krizia Amoroso, Roland Duculan, Bernhard Michalski, Jennifer Shue, Koki Tsuchiya, Marco D Burkhard, Andrew A Sama, Federico P Girardi, Frank P Cammisa, Carol A Mancuso, Alexander P Hughes
BACKGROUND/CONTEXT: Degenerative lumbar spondylolisthesis (DLS) is a prevalent spinal condition that can result in significant disability. DLS is thought to result from a combination of disc and facet joint degeneration, as well as various biological, biomechanical, and behavioral factors. One hypothesis is the progressive degeneration of segmental stabilizers, notably the paraspinal muscles, contributes to a vicious cycle of increasing slippage. PURPOSE: To examine the correlation between paraspinal muscle status on MRI and severity of slippage in patients with symptomatic DLS...
April 1, 2024: Spine Journal: Official Journal of the North American Spine Society
#23
JOURNAL ARTICLE
Mohammad Rahdar, Arda Kiani, Sima Noorali, Arezoo Bakhshandeh, Fatemeh Sadat Hosseini-Baharanchi, Shadi Shafaghi, Atefeh Abedini, Amir Behnam Kharazmi
BACKGROUND AND AIM: Cough is a common symptom among patients with sarcoidosis, and the Leicester Cough Questionnaire, a cough-specific quality-of-life measure, evaluates the impact of cough across physical, psychological, and social domains in patients with chronic cough. The aim of this study was cross-cultural adaptation and validation of Persian version of Leicester Cough Questionnaire (LCQ) in pulmonary sarcoidosis in Iran. METHODS: Psychometric analyses included translation and back translation of the questionnaire, face validity, content validity, construct validity, criterion-related validity, internal consistency, and test -retest reliability were performed...
March 26, 2024: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
#24
JOURNAL ARTICLE
Marzieh Ghiasi, Chi Chang, Amy L Shafrir, Allison F Vitonis, Naoko Sasamoto, Ana I Vazquez, Amy D DiVasta, Kristen Upson, Christine B Sieberg, Kathryn L Terry, Claudia B Holzman, Stacey A Missmer
Chronic pelvic pain is heterogeneous with potentially clinically informative subgroups. We aimed to identify subgroups of pelvic pain based on symptom patterns and investigate their associations with inflammatory and chronic pain-related comorbidities. Latent class analysis (LCA) identified subgroups of participants (n = 1255) from the Adolescence to Adulthood (A2A) cohort. Six participant characteristics were included in the LCA: severity, frequency, and impact on daily activities of both menstruation-associated (cyclic) and non-menstruation-associated (acyclic) pelvic pain...
April 2, 2024: Pain
#25
JOURNAL ARTICLE
Mendi J Muthinja, Carlos Othon Guelngar, Maouly Fall, Fatumah Jama, Huda Aldeen Shuja, Jamila Nambafu, Daniel Gams Massi, Oluwadamilola O Ojo, Njideka U Okubadejo, Funmilola Tolulope Taiwo, Alassane Mamadou Diop, Coudjou J D G de Chacus, Fodé Abass Cissé, Amara Cissé, Juzar Hooker, Dilraj Sokhi, Henry Houlden, Mie Rizig
BACKGROUND: Africans are underrepresented in Huntington's disease (HD) research. A European ancestor was postulated to have introduced the mutant Huntingtin (mHtt) gene to the continent; however, recent work has shown the existence of a unique Htt haplotype in South-Africa specific to indigenous Africans. OBJECTIVE: We aimed to investigate the CAG trinucleotide repeats expansion in the Htt gene in a geographically diverse cohort of patients with chorea and unaffected controls from sub-Saharan Africa...
April 2, 2024: Annals of Human Genetics
#26
JOURNAL ARTICLE
Vicente de Paulo Martins Coelho Junior, Nathaniel Toop, Peter Kobalka, Vikram B Chakravarthy
BACKGROUND: Just 5% of all cavernomas are located in the spine. Thoracic root-related subtypes are the rarest, with a total of 14 cases reported in the literature to date. Among them, only 4 presented with subarachnoid hemorrhage (SAH). OBSERVATIONS: A 65-year-old female presented after an ictus of headache with no neurological deficits. Computed tomography (CT) demonstrated sulcal SAH, with the remainder of the workup nondiagnostic for etiology. Three weeks later, she re-presented with acute thoracic back pain and thoracic myelopathy...
April 1, 2024: J Neurosurg Case Lessons
#27
JOURNAL ARTICLE
Adam M Staffaroni, Annie L Clark, Jack C Taylor, Hilary W Heuer, Mark Sanderson-Cimino, Amy B Wise, Sreya Dhanam, Yann Cobigo, Amy Wolf, Masood Manoochehri, Leah Forsberg, Carly Mester, Katherine P Rankin, Brian S Appleby, Ece Bayram, Andrea Bozoki, David Clark, R Ryan Darby, Kimiko Domoto-Reilly, Julie A Fields, Douglas Galasko, Daniel Geschwind, Nupur Ghoshal, Neill Graff-Radford, Murray Grossman, Ging-Yuek Hsiung, Edward D Huey, David T Jones, Maria I Lapid, Irene Litvan, Joseph C Masdeu, Lauren Massimo, Mario F Mendez, Toji Miyagawa, Belen Pascual, Peter Pressman, Vijay K Ramanan, Eliana Marisa Ramos, Katya Rascovsky, Erik D Roberson, M Carmela Tartaglia, Bonnie Wong, Bruce L Miller, John Kornak, Walter Kremers, Jason Hassenstab, Joel H Kramer, Bradley F Boeve, Howard J Rosen, Adam L Boxer
IMPORTANCE: Frontotemporal lobar degeneration (FTLD) is relatively rare, behavioral and motor symptoms increase travel burden, and standard neuropsychological tests are not sensitive to early-stage disease. Remote smartphone-based cognitive assessments could mitigate these barriers to trial recruitment and success, but no such tools are validated for FTLD. OBJECTIVE: To evaluate the reliability and validity of smartphone-based cognitive measures for remote FTLD evaluations...
April 1, 2024: JAMA Network Open
#28
JOURNAL ARTICLE
Stefan P Rautenbach, Lilith K Whittles, Gesine Meyer-Rath, Lise Jamieson, Thato Chidarikire, Leigh F Johnson, Jeffrey W Imai-Eaton
BACKGROUND: After successful intensive interventions to rapidly increase HIV awareness, coverage of antiretroviral therapy (ART), and viral suppression, HIV programmes in eastern and southern Africa are considering scaling back of some interventions, such as widespread general population HIV testing. We aimed to model whether scaling back of general population HIV testing in South Africa could result in a resurgence of the HIV epidemic or substantial slowing of declines in HIV incidence, resulting in increased long-term ART...
April 2024: Lancet. Public Health
#29
JOURNAL ARTICLE
Darcy C Esiason, Nicole Ciesinski, Chelsi N Nurse, Wendy Erler, Tom Hattrich, Ankita Deshpande, C Virginia O'Hayer
Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disorder of the central nervous system with common symptoms of rapid onset of eye pain, loss of vision, neck/back pain, paralysis, bowel and bladder dysfunction and heat sensitivity. The rare, unpredictable, and debilitating nature of NMOSD constitutes a unique psychological burden for patients and their caregivers, the specific nature and extent of which is not yet known. This mixed methods study, informed by both quantitative and qualitative data collected via self-report measures, focus groups, and in-depth interviews, aims to investigate and understand the psychological burden of patients with NMOSD and their caregiver/loved ones, so as to inform a specialized intervention...
2024: PloS One
#30
JOURNAL ARTICLE
Gabriela Salim de Castro, Leonardo R Gama, Alexandre Ferreira Ramos, Guilherme Gatti da Silva, Alexandre Abilio de Souza Teixeira, Edecio Cunha-Neto, Heraldo Possolo de Souza, Suely K Marie, Leda L Talib, Verônica Coelho, Jorge Kalil, Adriana Ladeira de Araujo, Ana Paula Ritto, Alessandro Rodrigo Belon, Amanda Soares Santos, Ana Paula Noronha Barrére, Márcio V Y Sawamura, Celina Almeida Lamas, Bruno Guedes Baldi, Carlos R R Carvalho, Leslie Domenici Kulikowski, Rodolfo Furlan Damiano, Marta Imamura, José Cesar Rosa Neto, Fabio S Lira, José Pinhata Otoch, Euripedes Constantino Miguel, Linamara Battistella, Orestes V Forlenza, Geraldo Busatto, Marilia Seelaender
INTRODUCTION: Post-COVID-19 condition (PCC) is characterised by a plethora of symptoms, with fatigue appearing as the most frequently reported. The alterations that drive both the persistent and post-acute disease newly acquired symptoms are not yet fully described. Given the lack of robust knowledge regarding the mechanisms of PCC we have examined the impact of inflammation in PCC, by evaluating serum cytokine profile and its potential involvement in inducing the different symptoms reported...
2024: Frontiers in Nutrition
#31
Bongseok Jung, Anas Abbas, Justin Han, Alex Ngan, Austen Katz, David Essig
Newer third generation percutaneous kyphoplasty (PKs) may minimize risks associated with older generation kyphoplasties such as new adjacent fractures, fracture progression, cement leakage, neurologic sequelae, and kyphosis. Additionally, posterior pedicle spinal fusion (PPSF) may minimize risk of long-term complications following PKs while maximizing the benefits of stable spinal alignment. The patient developed adjacent fracture progression, posterior retropulsion, and kyphosis following third generation kyphoplasty...
March 2024: Journal of Surgical Case Reports
#32
REVIEW
Hadi Al-Jamal, Sara Idriss, Rabih Roufayel, Ziad Abi Khattar, Ziad Fajloun, Jean-Marc Sabatier
In 2020, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) challenged the world with a global outbreak that led to millions of deaths worldwide. Coronavirus disease 2019 (COVID-19) is the symptomatic manifestation of this virus, which can range from flu-like symptoms to utter clinical complications and even death. Since there was no clear medicine that could tackle this infection or lower its complications with minimal adverse effects on the patients' health, the world health organization (WHO) developed awareness programs to lower the infection rate and limit the fast spread of this virus...
February 20, 2024: Viruses
#33
REVIEW
Leonard Jung, Gilbert Georg Klamminger, Bert Bier, Elke Eltze
Over the last century, the narrative of cervical cancer history has become intricately tied to virus research, particularly the human papillomavirus (HPV) since the 1970s. The unequivocal proof of HPV's causal role in cervical cancer has placed its detection at the heart of early screening programs across numerous countries. From a historical perspective, sexually transmitted genital warts have been already documented in ancient Latin literature; the remarkable symptoms and clinical descriptions of progressed cervical cancer can be traced back to Hippocrates and classical Greece...
February 27, 2024: Life
#34
JOURNAL ARTICLE
Q Y Ni, Y Mei, J B Wu, W M Hu, Y Yao
Objective: To investigate the occurrence of low back work-related musculoskeletal disorders (WMSDs) among workers in a container manufacturing factory, and to explore the influencing factors. Methods: In June 2022, 952 workers from a container factory were selected as the research objects by cluster random sampling. Through questionnaire survey, the incidence of low back WMSDs symptoms among workers in the past one year was collected, and the influencing factors of low back WMSDs were analyzed by logistic regression...
March 20, 2024: Chinese Journal of Industrial Hygiene and Occupational Diseases
#35
JOURNAL ARTICLE
Carol Ann Weis, Kathy Padkapayeva, Peter Smith, Jon Barrett, Victoria Landsman
OBJECTIVE: The aims of this study were to (1) examine if the location of pregnancy-related back pain impacts activities of daily living and absence from work and (2) determine which types of pain were more likely to persist postpartum. METHODS: This was a secondary analysis of data from an observational cohort study. Data were collected in Ontario between 2013 and 2014. Four pain location groups were identified, including low back pain (LBP), pelvic girdle pain (PGP), combined pain, and mixed pain...
March 26, 2024: Journal of Manipulative and Physiological Therapeutics
#36
Fawwad A Ansari, Stefan Gafoor, Mubashira Aftab, Zola Nlandu
Non-typhoidal Salmonella typically presents with gastroenteritis. However, an invasive Salmonella infection, which may be typically seen in immunocompromised patients, has a propensity for aortic involvement, especially in patients with risk factors for atherosclerosis. Here we present a 60-year-old female with multiple comorbid conditions and currently on immunosuppressants for rheumatoid arthritis, who presented with nausea, vomiting, and fever of three weeks duration and was found to have Salmonella bacteremia...
February 2024: Curēus
#37
JOURNAL ARTICLE
Gizem Arabacı, Batuhan S Cakir, Benjamin A Parris
Goal neglect refers to when an aspect of task instructions is not utilised due to increased competition between goal representations, an attentional limit theoretically linked to working memory. In an attempt to alleviate goal neglect and to investigate the association between dorsolateral prefrontal cortex (DLPFC)-supported working memory and goal neglect, we used high-frequency repetitive transcranial magnetic stimulation to the left DLPFC whilst participants completed the letter-monitoring task, a measure of goal neglect, and an N3-back task, a working memory task known to be affected by rTMS of the left DLPFC, following 20 min of active and sham stimulation (run on separate days)...
March 22, 2024: Brain Structure & Function
#38
JOURNAL ARTICLE
Suzanna M van Walraven, Leon C Witte, Femmeke Prinsze, Johanna C Wiersum-Osselton, Ivan Bank
BACKGROUND: Pain is a side effect of Granulocyte-Colony Stimulating Factor (G-CSF) administration. This prospective study investigates various aspects including pain perception occurring in Peripheral Blood Stem Cell (PBSC) donors. MATERIALS AND METHODS: Related and unrelated PBSC donors were prospectively studied. Donors recorded pain symptoms during the four-day period of G-CSF administration using the McGill Pain Questionnaire, a Visual Analog Scale and a pain diary...
March 19, 2024: Transfusion and Apheresis Science
#39
JOURNAL ARTICLE
Kang Chen, Fu-Guo Yang, Yuan-Chao Luo, Ren-Jian He
OBJECTIVE: To compare clinical efficacy and complication rate of percutaneous endoscopic transforaminal discectomy(PETD),percutaneous endoscopic interlaminar discectomy (PEID) and unilateral biportal endoscopic (UBE) in treating single-segment lumbar disc herniation(LDH). METHODS: From October 2019 to August 2021,121 LDH patients with single-segment treated by spinal endoscopy were retrospectively analyzed and divided into three groups. In PETD group,there were 48 patients,including 19 males and 29 females,aged from 18 to 72 years old with an average of (44...
March 25, 2024: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
#40
JOURNAL ARTICLE
Andreas Filis, Sergio M F Romualdo, Kay Engellandt, Ibrahim El-Battrawy, Dino Podlesek, Tareq A Juratli, Ilker Y Eyüpoglu, Gabriele Schackert, Mido Max Hijazi
BACKGROUND: Spinal dural arteriovenous fistulas (SDAVFs) are rare spinal vascular malformations, but account for 70 to 80% of all spinal arteriovenous malformations. SDAVFs can be treated either surgically or endovascularly, with surgical treatment appearing to lead to higher closure rates. Our aim was to analyze the demographic data, diagnostic history, treatment characteristics and clinical short- and long-term outcomes. METHODS: The medical records of 81 patients who underwent surgical ( n = 70, 86...
2024: Frontiers in Surgery
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
