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https://www.readbyqxmd.com/read/27910281/make-your-peer-reviews-more-organized-and-systematic-with-checklists
#1
EDITORIAL
Charon A Pierson
No abstract text is available yet for this article.
December 2016: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/27905411/the-rapid-formation-of-sputnik-planitia-early-in-pluto-s-history
#2
Douglas P Hamilton, S A Stern, J M Moore, L A Young
Pluto's Sputnik Planitia is a bright, roughly circular feature that resembles a polar ice cap. It is approximately 1,000 kilometres across and is centred on a latitude of 25 degrees north and a longitude of 175 degrees, almost directly opposite the side of Pluto that always faces Charon as a result of tidal locking. One explanation for its location includes the formation of a basin in a giant impact, with subsequent upwelling of a dense interior ocean. Once the basin was established, ice would naturally have accumulated there...
November 30, 2016: Nature
https://www.readbyqxmd.com/read/27881140/early-signs-of-multi-walled-carbon-nanotbues-degradation-in-macrophages-via-an-intracellular-ph-dependent-biological-mechanism-importance-of-length-and-functionalization
#3
Marion Landry, Mathieu Pinault, Stéphane Tchankouo, Émeline Charon, Audrey Ridoux, Jorge Boczkowski, Martine Mayne-L'Hermite, Sophie Lanone
BACKGROUND: Carbon nanotubes (CNT) can interact with the biological environment, which could participate in their associated toxicity. We recently demonstrated that pH is an important player of CNT fate inside macrophages. We wanted to further characterize such process, and therefore designed a study dedicated to decipher CNT biodegradation by macrophages, as a function of two major physico-chemical properties in regard with nanotoxicology; length and degree of functionalization. To achieve our aim, we synthesized, following a single initial production process, four MWCNT differing in length and/or surface chemistry: S-CNT (short), SF-CNT (short functionalized), L-CNT (long) and LF-CNT (long functionalized)...
November 24, 2016: Particle and Fibre Toxicology
https://www.readbyqxmd.com/read/27851731/reorientation-and-faulting-of-pluto-due-to-volatile-loading-within-sputnik-planitia
#4
James T Keane, Isamu Matsuyama, Shunichi Kamata, Jordan K Steckloff
Pluto is an astoundingly diverse, geologically dynamic world. The dominant feature is Sputnik Planitia-a tear-drop-shaped topographic depression approximately 1,000 kilometres in diameter possibly representing an ancient impact basin. The interior of Sputnik Planitia is characterized by a smooth, craterless plain three to four kilometres beneath the surrounding rugged uplands, and represents the surface of a massive unit of actively convecting volatile ices (N2, CH4 and CO) several kilometres thick. This large feature is very near the Pluto-Charon tidal axis...
December 1, 2016: Nature
https://www.readbyqxmd.com/read/27807808/predictive-factors-of-pathologic-complete-response-of-her2-positive-breast-cancer-after-preoperative-chemotherapy-with-trastuzumab-development-of-a-specific-predictor-and-study-of-its-utilities-using-decision-curve-analysis
#5
Clémentine Jankowski, S Guiu, M Cortet, C Charon-Barra, I Desmoulins, V Lorgis, L Arnould, P Fumoleau, B Coudert, R Rouzier, C Coutant, F Reyal
PURPOSE: The aim of this study was to assess the Institut Gustave Roussy/M.D. Anderson Cancer Center (IGR/MDACC) nomogram in predicting pathologic complete response (pCR) to preoperative chemotherapy in a cohort of human epidermal growth factor receptor 2 (HER2)-positive tumors treated with preoperative chemotherapy with trastuzumab. We then combine clinical and pathological variables associated with pCR into a new nomogram specific to HER2-positive tumors treated by preoperative chemotherapy with trastuzumab...
November 2, 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27701851/consent-to-publish-medical-case-reports
#6
Charon A Pierson
No abstract text is available yet for this article.
October 2016: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/27689896/atlas-based-shape-analysis-and-classification-of-retinal-optical-coherence-tomography-images-using-the-functional-shape-fshape-framework
#7
Sieun Lee, Nicolas Charon, Benjamin Charlier, Karteek Popuri, Evgeniy Lebed, Marinko V Sarunic, Alain Trouvé, Mirza Faisal Beg
We propose a novel approach for quantitative shape variability analysis in retinal optical coherence tomography images using the functional shape (fshape) framework. The fshape framework uses surface geometry together with functional measures, such as retinal layer thickness defined on the layer surface, for registration across anatomical shapes. This is used to generate a population mean template of the geometry-function measures from each individual. Shape variability across multiple retinas can be measured by the geometrical deformation and functional residual between the template and each of the observations...
September 20, 2016: Medical Image Analysis
https://www.readbyqxmd.com/read/27670115/spirochaete-flagella-hook-proteins-self-catalyse-a-lysinoalanine-covalent-crosslink-for-motility
#8
Michael R Miller, Kelly A Miller, Jiang Bian, Milinda E James, Sheng Zhang, Michael J Lynch, Patrick S Callery, Justin M Hettick, Andrew Cockburn, Jun Liu, Chunhao Li, Brian R Crane, Nyles W Charon
Spirochaetes are bacteria responsible for several serious diseases, including Lyme disease (Borrelia burgdorferi), syphilis (Treponema pallidum) and leptospirosis (Leptospira interrogans), and contribute to periodontal diseases (Treponema denticola)(1). These spirochaetes employ an unusual form of flagella-based motility necessary for pathogenicity; indeed, spirochaete flagella (periplasmic flagella) reside and rotate within the periplasmic space(2-11). The universal joint or hook that links the rotary motor to the filament is composed of ∼120-130 FlgE proteins, which in spirochaetes form an unusually stable, high-molecular-weight complex(9,12-17)...
August 8, 2016: Nature Microbiology
https://www.readbyqxmd.com/read/27629517/observed-glacier-and-volatile-distribution-on-pluto-from-atmosphere-topography-processes
#9
Tanguy Bertrand, François Forget
Pluto has a variety of surface frosts and landforms as well as a complex atmosphere. There is ongoing geological activity related to the massive Sputnik Planitia glacier, mostly made of nitrogen (N2) ice mixed with solid carbon monoxide and methane, covering the 4-kilometre-deep, 1,000-kilometre-wide basin of Sputnik Planitia near the anti-Charon point. The glacier has been suggested to arise from a source region connected to the deep interior, or from a sink collecting the volatiles released planetwide. Thin deposits of N2 frost, however, were also detected at mid-northern latitudes and methane ice was observed to cover most of Pluto except for the darker, frost-free equatorial regions...
December 1, 2016: Nature
https://www.readbyqxmd.com/read/27626378/the-formation-of-charon-s-red-poles-from-seasonally-cold-trapped-volatiles
#10
W M Grundy, D P Cruikshank, G R Gladstone, C J A Howett, T R Lauer, J R Spencer, M E Summers, M W Buie, A M Earle, K Ennico, J Wm Parker, S B Porter, K N Singer, S A Stern, A J Verbiscer, R A Beyer, R P Binzel, B J Buratti, J C Cook, C M Dalle Ore, C B Olkin, A H Parker, S Protopapa, E Quirico, K D Retherford, S J Robbins, B Schmitt, J A Stansberry, O M Umurhan, H A Weaver, L A Young, A M Zangari, V J Bray, A F Cheng, W B McKinnon, R L McNutt, J M Moore, F Nimmo, D C Reuter, P M Schenk
A unique feature of Pluto's large satellite Charon is its dark red northern polar cap. Similar colours on Pluto's surface have been attributed to tholin-like organic macromolecules produced by energetic radiation processing of hydrocarbons. The polar location on Charon implicates the temperature extremes that result from Charon's high obliquity and long seasons in the production of this material. The escape of Pluto's atmosphere provides a potential feedstock for a complex chemistry. Gas from Pluto that is transiently cold-trapped and processed at Charon's winter pole was proposed as an explanation for the dark coloration on the basis of an image of Charon's northern hemisphere, but not modelled quantitatively...
September 14, 2016: Nature
https://www.readbyqxmd.com/read/27589071/recycling-is-good-for-trash-but-unacceptable-for-scientific-literature
#11
EDITORIAL
Charon A Pierson
No abstract text is available yet for this article.
September 2016: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/27527593/charon-mediates-immune-deficiency-driven-parp-1-dependent-immune-responses-in-drosophila
#12
Yingbiao Ji, Colin Thomas, Nikita Tulin, Niraj Lodhi, Ernest Boamah, Vladimir Kolenko, Alexei V Tulin
Regulation of NF-κB nuclear translocation and stability is central to mounting an effective innate immune response. In this article, we describe a novel molecular mechanism controlling NF-κB-dependent innate immune response. We show that a previously unknown protein, termed as Charon, functions as a regulator of antibacterial and antifungal immune defense in Drosophila Charon is an ankyrin repeat-containing protein that mediates poly(ADP-ribose) polymerase-1 (PARP-1)-dependent transcriptional responses downstream of the innate immune pathway...
September 15, 2016: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/27509540/the-four-r-s-of-revising-and-resubmitting-a-manuscript
#13
EDITORIAL
Charon A Pierson
No abstract text is available yet for this article.
August 2016: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/27461236/a-family-based-genome-wide-association-study-reveals-an-association-of-spondyloarthritis-with-mapk14
#14
Félicie Costantino, Alice Talpin, Roula Said-Nahal, Ariane Leboime, Elena Zinovieva, Diana Zelenika, Ivo Gut, Céline Charon, Brigitte Izac, Michael Weissman, Gilles Chiocchia, John Reveille, Maxime Breban, Henri-Jean Garchon
OBJECTIVE: More than 40 loci have been associated with ankylosing spondylitis (AS), but less is known about genetic associations in spondyloarthritis (SpA) as a whole. We conducted a family-based genome-wide association study (GWAS) to identify new non-major histocompatibility complex (MHC) genetic factors associated with SpA. METHODS: 906 subjects from 156 French multiplex families, including 438 with SpA, were genotyped using Affymetrix 250K microarrays. Association was tested with Unphased...
July 26, 2016: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/27436199/structured-abstracts-improve-clarity-and-reach-your-intended-audience
#15
EDITORIAL
Charon A Pierson
No abstract text is available yet for this article.
July 2016: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/27427195/charon-s-coins
#16
Dominic Gascho, Simon Gentile, Stephan A Bolliger, Michael J Thali
No abstract text is available yet for this article.
September 2016: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/27423674/early-mri-in-neonatal-hypoxic-ischaemic-encephalopathy-treated-with-hypothermia-prognostic-role-at-2-year-follow-up
#17
Valérie Charon, Maïa Proisy, Gilles Bretaudeau, Bertrand Bruneau, Patrick Pladys, Alain Beuchée, Gladys Burnouf-Rose, Jean-Christophe Ferré, Céline Rozel
UNLABELLED: The prognostic role of early MRI (≤ 6 days of life) is still uncertain in hypoxic-ischaemic encephalopathy (HIE) treated with hypothermia. OBJECTIVE: To compare the prognostic value of early (≤ 6 days) and late MRIs (≥ 7 days) in predicting adverse outcome at 2 years old in asphyxiated term neonates treated with hypothermia. METHODS: This retrospective study included all asphyxiated neonates eligible for hypothermia treatment between November 2009 and July 2012...
August 2016: European Journal of Radiology
https://www.readbyqxmd.com/read/27402068/avoiding-ethics-pitfalls-in-publishing-a-perspective-from-cope
#18
Charon A Pierson
The mission of the Committee on Publication Ethics (COPE) is to promote integrity in research publication. COPE was started in 1997 with a small group of editors and now has a membership of more than 10,000. Throughout its history, COPE has provided a forum for discussion about ethical issues related to all aspects of scholarly publishing and developed resources to assist those who write, review, and edit scholarly work. This concise review provides examples of ethical issues related to authoring, reviewing, and editing scholarly manuscripts from the perspective of COPE...
July 12, 2016: Oral Diseases
https://www.readbyqxmd.com/read/27383706/liver-proteome-of-mice-with-different-genetic-susceptibilities-to-the-effects-of-fluoride
#19
Zohaib Nisar Khan, Aline de Lima Leite, Senda Charone, Isabela Tomazini Sabino, Tatiana Martini, Heloísa Aparecida Barbosa da Silva Pereira, Rodrigo Cardoso Oliveira, Marília Afonso Rabelo Buzalaf
OBJECTIVE: In this study, we investigated the differential pattern of protein expression in the liver of these mice to provide insights on why they have different responses to F. MATERIAL AND METHODS: Weanling male A/J and 129P3/J mice (n=10 from each strain) were pared and housed in metabolic cages with ad libitum access to low-F food and deionized water for 42 days. Liver proteome profiles were examined using nLC-MS/MS. Protein function was classified by GO biological process (Cluego v2...
May 2016: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/27292172/temporal-and-spatial-patterns-in-utilization-of-mental-health-services-during-and-after-hurricane-sandy-emergency-department-and-inpatient-hospitalizations-in-new-york-city
#20
Fangtao Tony He, Nneka Lundy De La Cruz, Donald Olson, Sungwoo Lim, Amber Levanon Seligson, Gerod Hall, Jillian Jessup, Charon Gwynn
OBJECTIVE: Hurricane Sandy made landfall on October 29, 2012, causing a coastal storm surge and extensive flooding, which led to the closure of several health care facilities in New York City (NYC) and prolonged interruptions in service delivery. The impact on mental health-related emergency department (ED) and inpatient hospital service utilization was studied. METHODS: Data came from the New York Statewide Planning and Research Cooperative System. We obtained mental health-related data among NYC residents from 2010 to 2013...
June 2016: Disaster Medicine and Public Health Preparedness
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