Read by QxMD icon Read


Charon A Pierson
No abstract text is available yet for this article.
October 2016: Journal of the American Association of Nurse Practitioners
Sieun Lee, Nicolas Charon, Benjamin Charlier, Karteek Popuri, Evgeniy Lebed, Marinko V Sarunic, Alain Trouvé, Mirza Faisal Beg
We propose a novel approach for quantitative shape variability analysis in retinal optical coherence tomography images using the functional shape (fshape) framework. The fshape framework uses surface geometry together with functional measures, such as retinal layer thickness defined on the layer surface, for registration across anatomical shapes. This is used to generate a population mean template of the geometry-function measures from each individual. Shape variability across multiple retinas can be measured by the geometrical deformation and functional residual between the template and each of the observations...
September 20, 2016: Medical Image Analysis
Michael R Miller, Kelly A Miller, Jiang Bian, Milinda E James, Sheng Zhang, Michael J Lynch, Patrick S Callery, Justin M Hettick, Andrew Cockburn, Jun Liu, Chunhao Li, Brian R Crane, Nyles W Charon
Spirochaetes are bacteria responsible for several serious diseases, including Lyme disease (Borrelia burgdorferi), syphilis (Treponema pallidum) and leptospirosis (Leptospira interrogans), and contribute to periodontal diseases (Treponema denticola)(1). These spirochaetes employ an unusual form of flagella-based motility necessary for pathogenicity; indeed, spirochaete flagella (periplasmic flagella) reside and rotate within the periplasmic space(2-11). The universal joint or hook that links the rotary motor to the filament is composed of ∼120-130 FlgE proteins, which in spirochaetes form an unusually stable, high-molecular-weight complex(9,12-17)...
2016: Nature Microbiology
Tanguy Bertrand, François Forget
Pluto has a variety of surface frosts and landforms as well as a complex atmosphere. There is ongoing geological activity related to the massive Sputnik Planum glacier, mostly made of nitrogen (N2) ice mixed with solid carbon monoxide and methane, covering the 4-kilometre-deep, 1,000-kilometre-wide basin of Sputnik Planumnear the anti-Charon point. The glacier has been suggested to arise from a source region connected to the deep interior, or from a sink collecting the volatiles released planetwide. Thin deposits of N2 frost, however, were also detected at mid-northern latitudes and methane ice was observed to cover most of Pluto except for the darker, frost-free equatorial regions...
September 19, 2016: Nature
W M Grundy, D P Cruikshank, G R Gladstone, C J A Howett, T R Lauer, J R Spencer, M E Summers, M W Buie, A M Earle, K Ennico, J Wm Parker, S B Porter, K N Singer, S A Stern, A J Verbiscer, R A Beyer, R P Binzel, B J Buratti, J C Cook, C M Dalle Ore, C B Olkin, A H Parker, S Protopapa, E Quirico, K D Retherford, S J Robbins, B Schmitt, J A Stansberry, O M Umurhan, H A Weaver, L A Young, A M Zangari, V J Bray, A F Cheng, W B McKinnon, R L McNutt, J M Moore, F Nimmo, D C Reuter, P M Schenk
A unique feature of Pluto's large satellite Charon is its dark red northern polar cap. Similar colours on Pluto's surface have been attributed to tholin-like organic macromolecules produced by energetic radiation processing of hydrocarbons. The polar location on Charon implicates the temperature extremes that result from Charon's high obliquity and long seasons in the production of this material. The escape of Pluto's atmosphere provides a potential feedstock for a complex chemistry. Gas from Pluto that is transiently cold-trapped and processed at Charon's winter pole was proposed as an explanation for the dark coloration on the basis of an image of Charon's northern hemisphere, but not modelled quantitatively...
September 14, 2016: Nature
Charon A Pierson
No abstract text is available yet for this article.
September 2016: Journal of the American Association of Nurse Practitioners
Yingbiao Ji, Colin Thomas, Nikita Tulin, Niraj Lodhi, Ernest Boamah, Vladimir Kolenko, Alexei V Tulin
Regulation of NF-κB nuclear translocation and stability is central to mounting an effective innate immune response. In this article, we describe a novel molecular mechanism controlling NF-κB-dependent innate immune response. We show that a previously unknown protein, termed as Charon, functions as a regulator of antibacterial and antifungal immune defense in Drosophila Charon is an ankyrin repeat-containing protein that mediates poly(ADP-ribose) polymerase-1 (PARP-1)-dependent transcriptional responses downstream of the innate immune pathway...
September 15, 2016: Journal of Immunology: Official Journal of the American Association of Immunologists
Charon A Pierson
No abstract text is available yet for this article.
August 2016: Journal of the American Association of Nurse Practitioners
Félicie Costantino, Alice Talpin, Roula Said-Nahal, Ariane Leboime, Elena Zinovieva, Diana Zelenika, Ivo Gut, Céline Charon, Brigitte Izac, Michael Weissman, Gilles Chiocchia, John Reveille, Maxime Breban, Henri-Jean Garchon
OBJECTIVE: More than 40 loci have been associated with ankylosing spondylitis (AS), but less is known about genetic associations in spondyloarthritis (SpA) as a whole. We conducted a family-based genome-wide association study (GWAS) to identify new non-major histocompatibility complex (MHC) genetic factors associated with SpA. METHODS: 906 subjects from 156 French multiplex families, including 438 with SpA, were genotyped using Affymetrix 250K microarrays. Association was tested with Unphased...
July 26, 2016: Annals of the Rheumatic Diseases
Charon A Pierson
No abstract text is available yet for this article.
July 2016: Journal of the American Association of Nurse Practitioners
Dominic Gascho, Simon Gentile, Stephan A Bolliger, Michael J Thali
No abstract text is available yet for this article.
September 2016: Forensic Science, Medicine, and Pathology
Valérie Charon, Maïa Proisy, Gilles Bretaudeau, Bertrand Bruneau, Patrick Pladys, Alain Beuchée, Gladys Burnouf-Rose, Jean-Christophe Ferré, Céline Rozel
UNLABELLED: The prognostic role of early MRI (≤ 6 days of life) is still uncertain in hypoxic-ischaemic encephalopathy (HIE) treated with hypothermia. OBJECTIVE: To compare the prognostic value of early (≤ 6 days) and late MRIs (≥ 7 days) in predicting adverse outcome at 2 years old in asphyxiated term neonates treated with hypothermia. METHODS: This retrospective study included all asphyxiated neonates eligible for hypothermia treatment between November 2009 and July 2012...
August 2016: European Journal of Radiology
Charon A Pierson
The mission of the Committee on Publication Ethics (COPE) is to promote integrity in research publication. COPE was started in 1997 with a small group of editors and now has a membership of more than 10,000. Throughout its history, COPE has provided a forum for discussion about ethical issues related to all aspects of scholarly publishing and developed resources to assist those who write, review, and edit scholarly work. This concise review provides examples of ethical issues related to authoring, reviewing, and editing scholarly manuscripts from the perspective of COPE...
July 12, 2016: Oral Diseases
Zohaib Nisar Khan, Aline de Lima Leite, Senda Charone, Isabela Tomazini Sabino, Tatiana Martini, Heloísa Aparecida Barbosa da Silva Pereira, Rodrigo Cardoso Oliveira, Marília Afonso Rabelo Buzalaf
OBJECTIVE: In this study, we investigated the differential pattern of protein expression in the liver of these mice to provide insights on why they have different responses to F. MATERIAL AND METHODS: Weanling male A/J and 129P3/J mice (n=10 from each strain) were pared and housed in metabolic cages with ad libitum access to low-F food and deionized water for 42 days. Liver proteome profiles were examined using nLC-MS/MS. Protein function was classified by GO biological process (Cluego v2...
May 2016: Journal of Applied Oral Science: Revista FOB
Fangtao Tony He, Nneka Lundy De La Cruz, Donald Olson, Sungwoo Lim, Amber Levanon Seligson, Gerod Hall, Jillian Jessup, Charon Gwynn
OBJECTIVE: Hurricane Sandy made landfall on October 29, 2012, causing a coastal storm surge and extensive flooding, which led to the closure of several health care facilities in New York City (NYC) and prolonged interruptions in service delivery. The impact on mental health-related emergency department (ED) and inpatient hospital service utilization was studied. METHODS: Data came from the New York Statewide Planning and Research Cooperative System. We obtained mental health-related data among NYC residents from 2010 to 2013...
June 2016: Disaster Medicine and Public Health Preparedness
Charon A Pierson
No abstract text is available yet for this article.
June 2016: Journal of the American Association of Nurse Practitioners
Sophie Le Guellec, Anne-Valérie Decouvelaere, Thomas Filleron, Isabelle Valo, Céline Charon-Barra, Yves-Marie Robin, Philippe Terrier, Christine Chevreau, Jean-Michel Coindre
An accurate histopathologic diagnosis is essential for an adequate treatment of soft tissue sarcomas. The diagnosis of malignant peripheral nerve sheath tumor (MPNST) can be complex, particularly outside the neurofibromatosis type 1 (NF1) context. MPNST is a rare malignancy, and due to the lack of specific histologic criteria, several differential diagnoses must be considered. A total of 350 patients diagnosed with MPNST (from 1990 to 2013) were retrieved from the French sarcoma network (RRePS) and the Conticabase (Connective Tissue Cancer Network database)...
July 2016: American Journal of Surgical Pathology
Gerod Hall, Jillian Jessup, Sungwoo Lim, Donald Olson, Amber Levanon Seligson, Fangtao Tony He, Nneka De La Cruz, Charon Gwynn
OBJECTIVE: Closure of several New York City (NYC) hospitals after Hurricane Sandy caused an unanticipated, extended surge in patient demand at open hospitals. This study identified hospitals with a significant increase in mental-health-related emergency department, inpatient, and outpatient visits from Medicaid patients displaced by Hurricane Sandy. METHODS: NYC Medicaid patients were classified into non-mutually-exclusive geographic categories corresponding to residence in areas served by Bellevue Hospital Center and Coney Island Hospital, the hurricane impact area, and all of NYC...
June 2016: Disaster Medicine and Public Health Preparedness
Charon A Pierson
No abstract text is available yet for this article.
May 2016: Journal of the American Association of Nurse Practitioners
Elsio A Wunder, Cláudio P Figueira, Nadia Benaroudj, Bo Hu, Brian A Tong, Felipe Trajtenberg, Jun Liu, Mitermayer G Reis, Nyles W Charon, Alejandro Buschiazzo, Mathieu Picardeau, Albert I Ko
Leptospira are unique among bacteria based on their helical cell morphology with hook-shaped ends and the presence of periplasmic flagella (PF) with pronounced spontaneous supercoiling. The factors that provoke such supercoiling, as well as the role that PF coiling plays in generating the characteristic hook-end cell morphology and motility, have not been elucidated. We have now identified an abundant protein from the pathogen L. interrogans, exposed on the PF surface, and named it Flagellar-coiling protein A (FcpA)...
August 2016: Molecular Microbiology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"