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https://www.readbyqxmd.com/read/28530555/arsenic-speciation-and-heavy-metal-distribution-in-polished-rice-grown-in-guangdong-province-southern-china
#1
Li Ma, Lin Wang, Jie Tang, Zhaoguang Yang
Arsenic speciation and heavy metal distributions have been investigated in locally grown rice grains from Guangdong Province, Southern China. A total of 41 polished rice grain samples were collected throughout Guangdong Province. Arsenite (As(III)), as the predominant form found in the rice, was positively correlated (p<0.01) with total As (tAs) concentration. However, the percentage of As(III) reduced while tAs concentration increased (r=-0.361, p<0.05), due to restricted accumulation and translocation of As(III) in rice grains at high level of tAs...
October 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28528292/cancer-incidence-in-the-western-australian-mining-industry-1996-2013
#2
Nita Sodhi-Berry, Alison Reid, Lin Fritschi, Aw Bill Musk, Roel Vermeulen, Nicholas de Klerk, Susan Peters
BACKGROUND: Miners are frequently exposed to established and potential carcinogens. We aimed to assess cancer incidence in miners relative to the general population and identify high-risk subgroups. METHODS: Incident cancers in Western Australian miners (n=153,922; 86% male) during 1996-2013 were identified. Indirectly standardised incidence ratios (SIRs) were calculated and mixed-effects Poisson models were used to calculate Incidence Rate Ratios (IRRs) to identify high-risk within-cohort subgroups...
May 18, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28506836/a-comprehensive-review-of-metal-induced-cellular-transformation-studies
#3
Qiao Yi Chen, Max Costa
In vitro transformation assays not only serve practical purposes in screening for potential carcinogenic substances in food, drug, and cosmetic industries, but more importantly, they provide a means of understanding the critical biological processes behind in vivo cancer development. In resemblance to cancer cells in vivo, successfully transformed cells display loss of contact inhibition, gain of anchorage independent growth, resistant to proper cell cycle regulation such as apoptosis, faster proliferation rate, potential for cellular invasion, and ability to form tumors in experimental animals...
May 12, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28506182/elemental-properties-of-copper-slag-and-measured-airborne-exposures-at-a-copper-slag-processing-facility
#4
Christopher Mugford, Jenna L Gibbs, Randy Boylstein
In 1974, the National Institute for Occupational Safety and Health recommended a ban on the use of abrasives containing >1% silica, giving rise to abrasive substitutes like copper slag. We present results from a National Institute for Occupational Safety and Health industrial hygiene survey at a copper slag processing facility that consisted of the collection of bulk samples for metals and silica; and full-shift area and personal air samples for dust, metals, and respirable silica. Carcinogens, suspect carcinogens, and other toxic elements were detected in all bulk samples, and area and personal air samples...
May 16, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28482304/a-comparison-of-pm-exposure-related-to-emission-hotspots-in-a-hot-and-humid-urban-environment-concentrations-compositions-respiratory-deposition-and-potential-health-risks
#5
Siming You, Zhiyi Yao, Yanjun Dai, Chi-Hwa Wang
Particle number concentration, particle size distribution, and size-dependent chemical compositions were measured at a bus stop, alongside a high way, and at an industrial site in a tropical city. It was found that the industry case had 4.93×10(7)-7.23×10(7) and 3.44×10(4)-3.69×10(4)#/m(3) higher concentration of particles than the bus stop and highway cases in the range of 0.25-0.65μm and 2.5-32μm, respectively, while the highway case had 6.01×10(5) and 1.86×10(3)#/m(3) higher concentration of particles than the bus stop case in the range of 0...
May 5, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28463793/caffeic-acid-phenethyl-ester-protects-the-brain-against-hexavalent-chromium-toxicity-by-enhancing-endogenous-antioxidants-and-modulating-the-jak-stat-signaling-pathway
#6
Ayman M Mahmoud, Sanaa M Abd El-Twab
Hexavalent chromium [Cr(VI)] is commonly used in industry, and is a proven toxin and carcinogen. However, the information regarding its neurotoxic mechanism is not completely understood. The present study was designed to scrutinize the possible protective effects of caffeic acid phenethyl ester (CAPE), a bioactive phenolic of propolis extract, on Cr(VI)-induced brain injury in rats, with an emphasis on the JAK/STAT signaling pathway. Rats received 2mg/kgK2CrO4 and concurrently treated with 20mg/kg CAPE for 30 days...
April 29, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28445826/exposure-to-fine-particulate-matter-causes-oxidative-and-methylated-dna-damage-in-young-adults-a-longitudinal-study
#7
Ching-Huang Lai, Han-Bin Huang, Yue-Cune Chang, Ting-Yao Su, Ying-Chuan Wang, Gia-Chi Wang, Jia-En Chen, Chin-Sheng Tang, Trong-Neng Wu, Saou-Hsing Liou
An increased understanding is needed of the physiological effects and plausible biological mechanisms that link PM2.5 (particulate matter with an aerodynamic diameter below 2.5μm) exposure to mortality and morbidities such as atherosclerosis and respiratory disease. PM2.5 causes carcinogenic health effects. Biomonitoring in humans has suggested that 8-oxo-7, 8-dihydro-2-deoxyguanosine (8-oxodG) and N7-methylguanine (N7-MeG) are correlated with oxidative and methylated DNA damage. Thus, it is meaningful to explore the mechanisms of mutagenesis and carcinogenesis associated with oxidative and methylated DNA damage by simultaneously measuring these two markers...
April 23, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28433929/pollution-characteristics-and-human-health-risks-of-potentially-eco-toxic-elements-ptes-in-road-dust-from-metropolitan-area-of-hefei-china
#8
Muhammad Ubaid Ali, Guijian Liu, Balal Yousaf, Qumber Abbas, Habib Ullah, Mehr Ahmed Mujtaba Munir, Biao Fu
This study aims to investigate the pollution characteristics of road dust and their associated health risks of potentially toxic elements (PTEs) to humans using array-based risk assessment models described by United States Environmental Protection Agency (USEPA) in a metropolitan area of Hefei, China. Geoaccumulation index (Igeo) was used to describe pollution characteristics of roadside dust in urban, periurban and industrial areas. Results indicate that industrial roadside dust was contaminated with Fe, Ni, Cu, Ti, V, Pb, Ba, Sb, Cr, Sn, Pb, As and Ga showing Igeo value (log2 (x)) between Igeo class 3 to 4...
April 14, 2017: Chemosphere
https://www.readbyqxmd.com/read/28433178/preparation-and-characterization-of-biodegradable-nanocomposites-derived-from-carboxymethyl-cellulose-and-hydroxyapatite
#9
K Azzaoui, E Mejdoubi, A Lamhamdi, S Jodeh, O Hamed, M Berrabah, S Jerdioui, R Salghi, N Akartasse, A Errich, Á Ríos, M Zougagh
Development of a cost-effective technology for extraction and quantification of carcinogenic and toxic organic materials which are widely used in the industry are critical to humans. Membrane technology received much attention and has already been widely used in this area. In this work, we offer a newly developed bio-based nanocomposite membrane for removal of bisphenol-A (BPA) from water. Three natural components hydroxyapatite (HAp), carboxymethyl cellulose and lysine as a diluent were used for making the bio-based membrane...
July 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28432963/health-hazards-of-child-labor-in-the-leather-products-and-surgical-instrument-manufacturing-industries-of-sialkot-pakistan
#10
Muhammad Junaid, Riffat Naseem Malik, De-Sheng Pei
Child labor is a major challenge in the developing countries and comprehensive health hazard identification studies on this issue are still lacking. Therefore, the current study is an effort to highlight the health concerns of child labor exposed in the key small scale industries of Sialkot, Pakistan. Our findings revealed jolting levels of heavy metals in the urine, blood, serum, saliva, and hair samples collected from the exposed children. For example, in the urine samples, Cd, Cr, Ni, and Pb were measured at the respective concentrations of 39...
April 19, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28432879/seasonal-variation-and-health-risk-assessment-of-organochlorine-compounds-in-urban-soils-of-novi-sad-serbia
#11
Biljana D Škrbić, Vesna Marinković, Igor Antić, Anita Petrović Gegić
The aim of this paper was to determine spatial and seasonal variation of 6 indicator polychlorinated biphenyls (PCBs) and 18 organochlorine pesticides (OCPs) in urban soils of Novi Sad, Serbia. Sixty surface soil samples were collected during both winter and summer season, from different types of locations: schools, recreational areas, residential and industrial zones. Samples were treated using the method of accelerated solvent extraction, which allows simultaneous extraction and clean up of PCBs and OCPs...
April 15, 2017: Chemosphere
https://www.readbyqxmd.com/read/28420806/the-association-of-occupational-metals-exposure-and-oxidative-damage-telomere-shortening-in-fitness-equipments-manufacturing-workers
#12
Jiunn-Liang Ko, Yu-Jung Cheng, Guan-Cen Liu, I-Lun Hsin, Hsiu-Ling Chen
The welding is the major working process in fitness equipment manufacturing industry, and International Agency for Research on Cancer has classified welding fumes as possibly carcinogenic to humans (Group 2B). The present study aimed to evaluate associations between the occupational exposure of metals and oxidative damage and telomere length shortening in workers involved in the manufacture of fitness equipment. The blood metal concentrations were monitored and malondialdehyde (MDA), alkaline Comet assay was determined as oxidative damage in 117 workers from two representative fitness equipment manufacturing plants...
April 14, 2017: Industrial Health
https://www.readbyqxmd.com/read/28409430/spatio-temporal-distribution-of-metals-in-household-dust-from-rural-semi-urban-and-urban-environments-in-the-niger-delta-nigeria
#13
Chukwujindu M A Iwegbue, Ejiro C Oliseyenum, Bice S Martincigh
Concentrations of metals in household dust samples from rural, semi-urban and urban zones of the Niger Delta in Nigeria were measured during both 2009 and 2014 with the aim of providing information on changes in the concentrations, distribution patterns, sources and risks of metals in these zones. The concentrations of metals in the dust samples were quantified by using inductively coupled plasma atomic emission spectrophotometry (ICP-AES) after digestion with aqua regia. The measured concentrations (mg kg(-1)) of metals in the three zones within the study periods were as follows: <LOQ-21...
April 13, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28403898/health-risks-associated-with-the-pharmaceuticals-in-wastewater
#14
EDITORIAL
Nasser Nassiri Koopaei, Mohammad Abdollahi
The overwhelming population growth in recent decades and water crisis along with limited and uneven geographical distribution of fresh water resources is a growing challenge for the economic and human development. Wastewater reclamation and use could be an alternative for intact water sources and a promising solution to water scarcity and unequal distribution. However, wastewater is a double-edged resource both as an accessible water source for food production and human usage and concurrently may carry uncharacterized content with unknown toxicological profile causing acute or long-term health risks...
April 12, 2017: Daru: Journal of Faculty of Pharmacy, Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/28400324/impact-of-anatase-titanium-dioxide-nanoparticles-on-mutagenic-and-genotoxic-response-in-chinese-hamster-lung-fibroblast-cells-v-79-the-role-of-cellular-uptake
#15
Abhishek Kumar Jain, Violet Aileen Senapati, Divya Singh, Kavita Dubey, Renuka Maurya, Alok Kumar Pandey
The unique physico-chemical properties of nano crystalline anatase titanium dioxide nanoparticles (TiO2 NPs) render them with different biological and chemical activities. Hence, it is widely used in industrial and consumer applications. Previous studies have shown the genotoxicity of TiO2 NPs. However, there is a paucity of data regarding mutagenicity of these NPs. In the present study, the cellular uptake, sub-cellular localization, cytotoxicity and short term DNA interaction of TiO2 NPs (1-100 μgmL(-1)) of diameter ranging from 12 to 25 nm on mammalian lung fibroblast cells (V-79) has been studied...
April 8, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28398075/disturbance-response-indicators-of-impatiens-walleriana-exposed-to-benzene-and-chromium
#16
V Campos, S S Lessa, R L Ramos, M C Shinzato, T A M Medeiros
The purpose of this study was to evaluate the remediation potential and disturbance response indicators of Impatiens walleriana exposed to benzene and chromium. Numerous studies over the years have found abundant evidence of the carcinogenicity of benzene and chromium (VI) in humans. Benzene and chromium are two toxic industrial chemicals commonly found together at contaminated sites, and one of the most common management strategies employed in the recovery of sites contaminated by petroleum products and trace metals is in situ remediation...
April 11, 2017: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/28397267/stability-assessment-of-lycopene-microemulsion-prepared-using-tomato-industrial-waste-against-various-processing-conditions
#17
Atefeh Amiri-Rigi, Soleiman Abbasi
BACKGROUND: Green separation techniques are growing at a greater rate than solvent extraction owing to the constant consumer drive to "go natural". Considering the increasing evidences of the health benefits of lycopene and massive tomato industrial waste, in the present study, using microemulsion technique the lycopene was extracted from tomato industrial waste and its mean droplet size and size distribution was determined. Moreover, the effects of pasteurization, sterilization, freeze-thaw cycles and UV irradiation on the thermodynamic stability, turbidity and lycopene concentration of the lycopene microemulsion were monitored...
April 11, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28395310/national-estimates-of-exposure-to-formaldehyde-in-italian-workplaces
#18
Alberto Scarselli, Marisa Corfiati, Davide Di Marzio, Sergio Iavicoli
Purpose: Formaldehyde is classified as human carcinogen and the association with nasopharyngeal cancer has been observed in many epidemiological studies. The aim of this study is to evaluate data about occupational exposure levels to formaldehyde in the Italian working force. Methods: Airborne concentrations of formaldehyde were extracted from the Italian database on occupational exposure to carcinogens and refer to the period 1996-2014. Descriptive statistics were calculated for exposure-related variables...
January 1, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/28385577/carbamates-and-ich-m7-classification-making-use-of-expert-knowledge
#19
Rachel Hemingway, Adrian Fowkes, Richard V Williams
Carbamates are widely used in the chemical industry so understanding their toxicity is important to safety assessment. Carbamates have been associated with certain toxicities resulting in publication of structural alerts, including alerts for mutagenicity. Structural alerts for bacterial mutagenicity can be used in combination with statistical systems to enable ICH M7 classification, which allows assessment of the genotoxic risk posed by pharmaceutical impurities. This study tested a hypothetical bacterial mutagenicity alert for carbamates and examined the impact it would have on ICH M7 classifications using (Q)SAR predictions from the expert rule-based system Derek Nexus and the statistical-based system Sarah Nexus...
April 4, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28384248/acute-oral-dose-of-sodium-nitrite-induces-redox-imbalance-dna-damage-metabolic-and-histological-changes-in-rat-intestine
#20
Fariheen Aisha Ansari, Shaikh Nisar Ali, Hussain Arif, Aijaz Ahmed Khan, Riaz Mahmood
Industrialization and unchecked use of nitrate/nitrite salts for various purposes has increased human exposure to high levels of sodium nitrite (NaNO2) which can act as a pro-oxidant and pro-carcinogen. Oral exposure makes the gastrointestinal tract particularly susceptible to nitrite toxicity. In this work, the effect of administration of a single acute oral dose of NaNO2 on rat intestine was studied. Animals were randomly divided into four groups and given single doses of 20, 40, 60 and 75 mg NaNO2/kg body weight...
2017: PloS One
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