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https://www.readbyqxmd.com/read/28230706/first-presentation-acute-rheumatic-fever-is-preventable-in-a-community-setting-a-school-based-intervention
#1
Diana Lennon, Philippa Anderson, Melissa Kerdemelidis, Elizabeth Farrell, Suzanne Crengle Mahi, Teuila Percival, David Jansen, Joanna Stewart
BACKGROUND: Robust evidence is lacking for community initiatives to prevent first presentation acute rheumatic fever (ARF) by group A streptococcal (GAS) pharyngitis treatment. METHODS: We measured the effect of introducing a sore throat clinic program on first presentation ARF into 61 year 1-8 schools with students aged 5-13years (population ~ 25,000) in Auckland, New Zealand. The study period was 2010-2016. A generalized linear mixed model investigated ARF rate changes before and after the staggered introduction of school clinics...
February 22, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28230458/progression-to-type-2-diabetes-and-its-effect-on-health-care-costs-in-low-income-and-insured-patients-with-prediabetes-a-retrospective-study-using-medicaid-claims-data
#2
Jun Wu, Eileen Ward, Tiffaney Threatt, Z Kevin Lu
BACKGROUND: Prediabetes is a high-risk factor for progression to diabetes. Without lifestyle changes, such as weight loss and moderate physical activity, 15%-30% of people with prediabetes are projected to develop type 2 diabetes within 5 years. Progression to diabetes increases the financial burden significantly for patients and health care systems. Populations with low socioeconomic status are associated with a higher risk of diabetes. However, knowledge is limited about the effect of transition to diabetes on future costs incurred in low-income populations...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28230457/comparative-effectiveness-of-rapid-acting-insulins-in-adults-with-diabetes
#3
Patrick N Racsa, Yunus Meah, Jeffrey J Ellis, Kimberly R Saverno
BACKGROUND: Although there are a variety of insulin products and new delivery modalities available, the absence of direct clinical and economic comparisons can make treatment planning and formulary decision making difficult. Direct comparisons between insulin aspart and insulin lispro from a large heterogeneous population are not available. OBJECTIVE: To assess differences in clinical outcomes, medication adherence, utilization, and total health care costs between aspart and lispro and vial versus pen modalities for administering these short-acting insulin analogs...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28230454/adherence-persistence-and-health-care-costs-for-patients-receiving-dipeptidyl-peptidase-4-inhibitors
#4
Karen L Rascati, Karen Worley, Yunus Meah, Damian Everhart
BACKGROUND: The dipeptidyl peptidase-4 (DPP-4) inhibitors are among the newer, yet more established, classes of diabetes medications. OBJECTIVE: To compare adherence, persistence, and health care costs among patients taking DPP-4 inhibitors. METHODS: Claims were extracted from Humana Medicare Advantage Prescription Drug (MAPD) or commercial plans for patients aged > 18 years with ≥ 1 prescription filled for a DPP-4 inhibitor between July 1, 2011, and March 31, 2013...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28229562/out-of-pocket-costs-and-burden-among-rural-breast-cancer-survivors
#5
Maria Pisu, Andres Azuero, Rachel Benz, Patrick McNees, Karen Meneses
Little is known about out-of-pocket (OOP) costs incurred for medical and health needs by rural breast cancer survivors and what factors may be associated with higher OOP costs and the associated economic burden. Data were examined for 432 survivors participating in the Rural Breast Cancer Survivor Intervention trial. OOP costs were collected using the Work and Finances Inventory survey at baseline and four assessments every 3 months. Mean and median OOP costs and burden (percent of monthly income spent on OOP costs) were reported and factors associated with OOP costs and burden identified with generalized linear models fitted with over-dispersed gamma distributions and logarithmic links (OOP costs) and with beta distributions with logit link (OOP burden)...
February 23, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28229328/physical-exercise-vegetable-and-fruit-intake-and-health-related-quality-of-life-in-chinese-breast-cancer-survivors-a-cross-sectional-study
#6
Xiao-Huan Gong, Ji-Wei Wang, Jiang Li, Xue-Fen Chen, Li Sun, Zheng-Ping Yuan, Jin-Ming Yu
INTRODUCTION: Breast cancer has long-term effects on health-related quality of life (HRQOL) of cancer survivors after treatment. Few research studies have focused on the association between health behaviors and HRQOL of Chinese breast cancer survivors (BCS). The aim of this study was to examine the separate and combined influence of physical exercise, vegetable and fruit intake on health-related quality of life of BCS. METHODS: A cross-sectional study was conducted among BCS from April to July 2013, in Shanghai, China...
February 22, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28229222/estimation-of-abnormal-temperature-effects-on-elderly-mortality-in-south-korea-using-the-temperature-deviation-index
#7
Giehae Choi, Hyun-Joo Bae, Youn-Hee Lim
Recent studies have revealed that the effect of temperature on mortality has changed over time. One of the major contributors to the changes is adaptation. We aimed to understand the relationship between elderly mortality and temperature anomaly using the temperature deviation index (TDI), which considers exposure history. Summertime (May to September) mortality data from 1996 to 2014 and meteorological data from 1971 to 2014 were obtained for 16 regions covering South Korea. The TDI was defined as the target day's temperature abnormality compared to previous 25 years' apparent temperature (AT)...
February 22, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28227753/statistically-significant-time-varying-neural-connectivity-estimation-using-generalized-partial-directed-coherence
#8
Pedro L C Rodrigues, Luiz A Baccala, Pedro L C Rodrigues, Luiz A Baccala, Pedro L C Rodrigues, Luiz A Baccala
This paper illustrates the effectiveness of generalized partial directed coherence (gPDC) in characterizing time-varying neural connectivity by properly extrapolating its single trial asymptotic statistical results to a multi trial setting. Time-varying estimation is performed with a sliding-window procedure based on the proposal in [1], whereby a time-frequency map of the connectivity between channels is built. The technique is validated on a non-linear toy model generating simulated EEG and then applied to a publicly available real EEG dataset for benchmarking purposes...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227302/the-role-of-electromechanical-delay-in-modelling-the-emg-force-relationship-during-quasi-dynamic-contractions-of-the-upper-limb
#9
Gregg Johns, Evelyn Morin, Keyvan Hashtrudi-Zaad, Gregg Johns, Evelyn Morin, Keyvan Hashtrudi-Zaad, Keyvan Hashtrudi-Zaad, Gregg Johns, Evelyn Morin
There is a discontinuity in published electromechanical delays (EMD) in upper-limb muscles and the state-of-the-art in modelling end-point force from electromyographic signals collected from one or more muscles. Published values are typically in the range of 10 to 30ms, depending on the nature of the contraction. In published literature where the EMG-force relationship is modelled, generally a delay of 100ms or more is induced during linear enveloping to match the EMD. The implications of EMD on end-point force prediction were considered using inter-session end-point force modelling with a support-vector-regression model...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227294/early-diagnosis-of-nafld-nash-transition-using-mid-infrared-spectroscopy
#10
Siouar Bensaid, Amar Kachenoura, Nathalie Costet, Victor De Ledinghen, Julien Vergniol, Fabrice Laine, Bruno Turlin, Hugues Tariel, Lotfi Senhadji, Siouar Bensaid, Amar Kachenoura, Nathalie Costet, Victor De Ledinghen, Julien Vergniol, Fabrice Laine, Bruno Turlin, Hugues Tariel, Lotfi Senhadji, Hugues Tariel, Siouar Bensaid, Victor De Ledinghen, Fabrice Laine, Bruno Turlin, Lotfi Senhadji, Amar Kachenoura, Julien Vergniol, Nathalie Costet
Non-alcoholic fatty liver disease (NAFLD) is defined as an excessive accumulation of fat in the liver in the absence of excessive drinking of alcohol. Initially considered as benign and self-limited, NAFLD may progress to the malignant stage of non-alcoholic steatohepatitis (NASH) characterized by degenerate hepatocellular ballooning and lobular inflammation. NASH can lead to hepatic fibrosis and ultimately to cirrhosis and hepatocellular carcinoma. Unfortunately, the transition from NAFLD to NASH is difficult to detect so far...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226922/finite-element-method-modeling-to-assess-laplacian-estimates-via-novel-variable-inter-ring-distances-concentric-ring-electrodes
#11
Oleksandr Makeyev, Walter G Besio, Oleksandr Makeyev, Walter G Besio, Walter G Besio, Oleksandr Makeyev
Noninvasive concentric ring electrodes are a promising alternative to conventional disc electrodes. Currently, superiority of tripolar concentric ring electrodes over disc electrodes, in particular, in accuracy of Laplacian estimation has been demonstrated in a range of applications. In our recent work we have shown that accuracy of Laplacian estimation can be improved with multipolar concentric ring electrodes using a general approach to estimation of the Laplacian for an (n + 1)-polar electrode with n rings using the (4n + 1)-point method for n ≥ 2...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226853/generalized-binary-noise-stimulation-enables-time-efficient-identification-of-input-output-brain-network-dynamics
#12
Yuxiao Yang, Maryam M Shanechi, Yuxiao Yang, Maryam M Shanechi, Yuxiao Yang, Maryam M Shanechi
Identification of input-output (IO) dynamics of brain networks in response to electrical stimulation is essential for devising closed-loop therapies for neurological disorders such as major depression. A critical component for accurate IO identification is the stimulation input design. The time available for open-loop stimulation to perform system identification is typically limited. While our prior design of a binary noise (BN) modulated input pattern satisfies the requirements for optimal identification and clinical safety, it does not incorporate any prior information about the underlying network...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226817/effective-connectivity-matrix-for-neural-ensembles
#13
Qi She, Winnie K Y So, Rosa H M Chan, Qi She, Winnie K Y So, Rosa H M Chan, Rosa H M Chan, Qi She, Winnie K Y So
In this paper, we present an efficient framework to study the directional interactions within the multiple-input multiple-output (MIMO) biological neural network from spiketrain data. We used an efficient generalized linear model (GLM) with Laguerre basis functions to model a MIMO neural system, and developed an Effective Connectivity Matrix (ECM) to visualize excitatory and inhibitory connections within the neural network. A new causality representation was developed based on system dynamics. Statistical test was applied to identify the significance of the measured causality...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226613/using-demographic-and-time-series-physiological-features-to-classify-sepsis-in-the-intensive-care-unit
#14
Kristin Gunnarsdottir, Vijay Sadashivaiah, Matthew Kerr, Sabato Santaniello, Sridevi V Sarma, Kristin Gunnarsdottir, Vijay Sadashivaiah, Matthew Kerr, Sabato Santaniello, Sridevi V Sarma, Sridevi V Sarma, Sabato Santaniello, Kristin Gunnarsdottir, Matthew Kerr, Vijay Sadashivaiah
Sepsis, a systemic inflammatory response to infection, is a major health care problem that affects millions of patients every year in the intensive care units (ICUs) worldwide. Despite the fact that ICU patients are heavily instrumented with physiological sensors, early sepsis detection remains challenging, perhaps because clinicians identify sepsis by (i) using static scores derived from bed-side measurements individually, and (ii) deriving these scores at a much slower rate than the rate for which patient data is collected...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226298/the-effect-of-muscle-fatigue-and-low-back-pain-on-lumbar-movement-variability-and-complexity
#15
C M Bauer, F M Rast, M J Ernst, A Meichtry, J Kool, S M Rissanen, J H Suni, M Kankaanpää
INTRODUCTION: Changes in movement variability and complexity may reflect an adaptation strategy to fatigue. One unresolved question is whether this adaptation is hampered by the presence of low back pain (LBP). This study investigated if changes in movement variability and complexity after fatigue are influenced by the presence of LBP. It is hypothesised that pain free people and people suffering from LBP differ in their response to fatigue. METHODS: The effect of an isometric endurance test on lumbar movement was tested in 27 pain free participants and 59 participants suffering from LBP...
February 13, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/28225921/model-for-simulated-training-of-laparoscopic-gastroenterostomy
#16
Márcio Alencar Barreira, Delano Gurgel Siveira, Hermano Alexandre Lima Rocha, Luiz Gonzaga de Moura, Charles Jean Gomes de Mesquita, Gleydson Cesar de Oliveira Borges
Purpose: To develop a model of gastroenterostomy and to analyze the acquisition of skills after training by simulation. Methods: Experimental longitudinal study and of a quantitative character. The sample consisted of twelve general surgery residents from four hospitals. The training consisted of making ten anastomoses divided equally into five sessions and it took place over a period of six weeks. The evaluation of the anastomoses considered the time and the analysis of the operative technique through the global evaluation scale Objective Structured Assessment of Technical Skills (OSATS)...
January 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28225909/tuberculosis-as-a-marker-of-inequities-in-the-context-of-socio-spatial-transformation
#17
Alexandre San Pedro, Gerusa Gibson, Jefferson Pereira Caldas Dos Santos, Luciano Medeiros de Toledo, Paulo Chagastelles Sabroza, Rosely Magalhães de Oliveira
OBJECTIVE: This study aims to analyze the association between the incidence of tuberculosis and different socioeconomic indicators in a territory of intense transformation of the urban space. METHODS: This is an ecological study, whose analysis units were the neighborhoods of the city of Itaboraí, state of Rio de Janeiro, Brazil. The data have been analyzed by generalized linear models. The response variable was incidence of tuberculosis from 2006 to 2011. The independent variables were the socio-demographic indicators...
February 16, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28225777/linear-mixed-effects-models-to-describe-length-weight-relationships-for-yellow-croaker-larimichthys-polyactis-along-the-north-coast-of-china
#18
Qiuyun Ma, Yan Jiao, Yiping Ren
In this study, length-weight relationships and relative condition factors were analyzed for Yellow Croaker (Larimichthys polyactis) along the north coast of China. Data covered six regions from north to south: Yellow River Estuary, Coastal Waters of Northern Shandong, Jiaozhou Bay, Coastal Waters of Qingdao, Haizhou Bay, and South Yellow Sea. In total 3,275 individuals were collected during six years (2008, 2011-2015). One generalized linear model, two simply linear models and nine linear mixed effect models that applied the effects from regions and/or years to coefficient a and/or the exponent b were studied and compared...
2017: PloS One
https://www.readbyqxmd.com/read/28224383/oncologist-and-organizational-factors-associated-with-variation-in-breast-cancer-multigene-testing
#19
Tracy A Lieu, G Thomas Ray, Stephanie R Prausnitz, Laurel A Habel, Stacey Alexeeff, Yan Li, Scott D Ramsey, Charles E Phelps, Neetu Chawla, Suzanne C O'Neill, Jeanne S Mandelblatt
PURPOSE: Multigene testing for breast cancer recurrence risk became available in 2007, yet many eligible patients remain untested. This study evaluated variation in testing rates, and oncologist and organizational factors associated with variation, in a setting without financial influences on testing. METHODS: We conducted a retrospective cohort study using electronic data and oncologist surveys within Kaiser Permanente Northern California, a large integrated health care system...
February 21, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28223945/toward-respiratory-assessment-using-depth-measurements-from-a-time-of-flight-sensor
#20
Charles Sharp, Vahid Soleimani, Sion Hannuna, Massimo Camplani, Dima Damen, Jason Viner, Majid Mirmehdi, James W Dodd
Introduction: There is increasing interest in technologies that may enable remote monitoring of respiratory disease. Traditional methods for assessing respiratory function such as spirometry can be expensive and require specialist training to perform and interpret. Remote, non-contact tracking of chest wall movement has been explored in the past using structured light, accelerometers and impedance pneumography, but these have often been costly and clinical utility remains to be defined. We present data from a 3-Dimensional time-of-flight camera (found in gaming consoles) used to estimate chest volume during routine spirometry maneuvres...
2017: Frontiers in Physiology
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