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low level laser therapy inflammation

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https://www.readbyqxmd.com/read/28161653/low-level-laser-therapy-lllt-accelerates-the-sternomastoid-muscle-regeneration-process-after-myonecrosis-due-to-bupivacaine
#1
Cristiane Neves Alessi Pissulin, Ana Angélica Henrique Fernandes, Alejandro Manuel Sanchez Orellana, Renata Calciolari Rossi E Silva, Selma Maria Michelin Matheus
BACKGROUND: Because of its long-lasting analgesic action, bupivacaine is an anesthetic used for peripheral nerve block and relief of postoperative pain. Muscle degeneration and neurotoxicity are its main limitations. There is strong evidence that low-level laser therapy (LLLT) assists in muscle and nerve repair. The authors evaluated the effects of a Gallium Arsenide laser (GaAs), on the regeneration of muscle fibers of the sternomastoid muscle and accessory nerve after injection of bupivacaine...
January 26, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28088107/gaas-laser-therapy-reestablishes-the-morphology-of-the-nmj-and-nachrs-after-injury-due-to-bupivacaine
#2
Cristiane Neves Alessi Pissulin, Paula Aiello Tomé de Souza Castro, Flávio Codina, Carina Guidi Pinto, Ivan Jose Vechetti-Junior, Selma Maria Michelin Matheus
BACKGROUND: Local anesthetics are used to relieve pre- and postoperative pain, acting on both sodium channels and nicotinic acetylcholine receptors (nAChR) at the neuromuscular junction (NMJ). Bupivacaine acts as a non-competitive antagonist and has limitations, such as myotoxicity, neurotoxicity, and inflammation. Low-level laser therapy (LLLT) has anti-inflammatory, regenerative, and analgesic effects. The aim of the present study was to evaluate the effects of a gallium arsenide laser (GaAs) on the morphology of the NMJ and nAChRs after application of bupivacaine in the sternomastoid muscle...
December 22, 2016: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28075022/the-mechanistic-basis-for-photobiomodulation-therapy-of-neuropathic-pain-by-near-infrared-laser-light
#3
Vanessa Milanesi Holanda, Maria Cristina Chavantes, Xingjia Wu, Juanita J Anders
BACKGROUND AND OBJECTIVE: Various irradiances have been reported to be beneficial for the treatment of neuropathic pain with near infrared light. However, the mechanistic basis for the beneficial outcomes may vary based on the level of irradiance or fluence rate used. Using in vivo and in vitro experimental models, this study determined the mechanistic basis of photobiomodulation therapy (PBMT) for the treatment of neuropathic pain using a high irradiance. STUDY DESIGN/MATERIALS AND METHODS: In vitro experiments: Cultured, rat DRG were randomly assigned to control or laser treatment (LT) groups with different irradiation times (2, 5, 30, 60, or 120 seconds)...
January 11, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28001759/transcranial-low-level-laser-light-therapy-for-brain-injury
#4
Connor Thunshelle, Michael R Hamblin
BACKGROUND: Low-level laser therapy (LLLT) or photobiomodulation (PBM) is a possible treatment for brain injury, including traumatic brain injury (TBI). METHODS: We review the fundamental mechanisms at the cellular and molecular level and the effects on the brain are discussed. There are several contributing processes that have been proposed to lead to the beneficial effects of PBM in treating TBI such as stimulation of neurogenesis, a decrease in inflammation, and neuroprotection...
December 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27924419/beneficial-effect-of-low-level-laser-therapy-in-acute-lung-injury-after-i-i-r-is-dependent-on-the-secretion-of-il-10-and-independent-of-the-tlr-myd88-signaling
#5
J L Carvalho, A Britto, A P Ligeiro de Oliveira, H Castro-Faria-Neto, R Albertini, E Anatriello, F Aimbire
The use of low-level laser for lung inflammation treatment has been evidenced in animal studies as well as clinical trials. The laser action mechanism seems to involve downregulation of neutrophil chemoattractants and transcription factors. Innate immune responses against microorganisms may be mediated by toll-like receptors (TLR). Intestinal ischemia and reperfusion (i-I/R) lead to bacterial product translocation, such as endotoxin, which consequently activates TLRs leading to intestinal and lung inflammation after gut trauma...
February 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/27913970/radiological-and-biochemical-effects-ctx-ii-mmp-3-8-and-13-of-low-level-laser-therapy-lllt-in-chronic-osteoarthritis-in-al-kharj-saudi-arabia
#6
Gopal Nambi S, Walid Kamal, Julie George, Elbagir Manssor
Inflammation of synovial membrane and degeneration of articular cartilage in osteoarthritis (OA) lead to major changes in joint space width (JSW) and biochemical components such as collagen-II telopeptide (CTX-II) and matrix metallo protineases (MMP-3, 8, and 13). Low-level laser therapy (LLLT) is thought to have an analgesic effect as well as biomodulatory effect on microcirculation and cartilage regeneration in animal studies. The objective of this study was to examine the analgesic and biochemical effect of LLLT in patients with knee osteoarthritis...
February 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/27861614/photobiomodulation-with-pulsed-and-continuous-wave-near-infrared-laser-810-nm-al-ga-as-augments-dermal-wound-healing-in-immunosuppressed-rats
#7
Gaurav K Keshri, Asheesh Gupta, Anju Yadav, Sanjeev K Sharma, Shashi Bala Singh
Chronic non-healing cutaneous wounds are often vulnerable in one or more repair phases that prevent normal healing and pose challenges to the use of conventional wound care modalities. In immunosuppressed subject, the sequential stages of healing get hampered, which may be the consequences of dysregulated or stagnant wound inflammation. Photobiomodulation (PBM) or low-level laser (light) therapy (LLLT) emerges as a promising drug-free, non-invasive biophysical approach for promoting wound healing, reduction of inflammation, pain and restoration of functions...
2016: PloS One
https://www.readbyqxmd.com/read/27851931/combined-therapy-using-low-level-laser-and-chitosan-policaju-hydrogel-for-wound-healing
#8
Adelmo C Aragão-Neto, Paulo A G Soares, Maria H M Lima-Ribeiro, Elaine J A Carvalho, Maria T S Correia, Maria G Carneiro-da-Cunha
We have evaluated the effect of POLI-CHI hydrogel based on policaju (POLI) from cashew tree (Anacardium occidentale L.) gum and chitosan (CHI), associated or not with Low level laser therapy (LLLT), in wound healing. Sixty male Wistar rats were assigned into four groups: POLI-CHI hydrogel (H); LLLT (L); POLI-CHI with LLLT (HL) and saline control (C). Macroscopic evaluations were carried out using clinical observations and area measurements, as well as microscopic analysis by histological criteria. H and HL presented more esthetical scar tissue and larger wound contraction compared to C...
February 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27815990/low-level-laser-therapy-for-beta-amyloid-toxicity-in-rat-hippocampus
#9
Yujiao Lu, Ruimin Wang, Yan Dong, Donovan Tucker, Ningjun Zhao, Md Ejaz Ahmed, Ling Zhu, Timon Cheng-Yi Liu, Robert M Cohen, Quanguang Zhang
Beta amyloid (Aβ) is well accepted to play a central role in the pathogenesis of Alzheimer's disease (AD). The present work evaluated the therapeutic effects of low-level laser irradiation (LLI) on Aβ-induced neurotoxicity in rat hippocampus. Aβ 1-42 was injected bilaterally to the hippocampus CA1 region of adult male rats, and 2-minute daily LLI treatment was applied transcranially after Aβ injection for 5 consecutive days. LLI treatment suppressed Aβ-induced hippocampal neurodegeneration and long-term spatial and recognition memory impairments...
January 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/27813716/effects-of-low-level-laser-therapy-in-orthodontic-patients-on-immediate-inflammatory-response-after-mini-implants-insertion-a-preliminary-report
#10
Mario S Yanaguizawa, Selly S Suzuki, Elizabeth F Martinez, Hideo Suzuki, Maria Cristina J Pelegrin, Aguinaldo S Garcez
BACKGROUND: The primary stability of a mini-implant is crucial to treatment sequence since most orthodontic mini-implant failures occur at an early stage. Irritation or inflammation of peri-implant tissues has been related to decreasing mini-implant success. PURPOSE: This study evaluates the effect of low-level laser therapy on initial inflammation after orthodontic mini-implants installation. METHODS: Ten volunteers received two mini-implants (1...
January 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27704296/photodynamic-therapy-decrease-immune-inflammatory-mediators-levels-during-periodontal-maintenance
#11
Priscila Vivas da Cruz Andrade, Vanessa Tubero Euzebio Alves, Verônica Franco de Carvalho, Michelle De Franco Rodrigues, Claudio Mendes Pannuti, Marinella Holzhausen, Giorgio De Micheli, Marina Clemente Conde
Antimicrobial photodynamic therapy (aPDT) was introduced as a promising adjuvant therapy on the periodontal treatment. The aim of this study was to evaluate the effect of aPDT on inflammatory mediator levels in residual periodontal pockets of patients with severe chronic periodontitis under periodontal maintenance, during 12 months follow-up. A randomized controlled trial study was conducted in 28 patients with severe chronic periodontitis. After non-surgical periodontal treatment, patients with at least four teeth with residual pocket probing depth (PPD) ≥4 mm were randomly assigned to either aPDT or control group...
January 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/27651678/low-level-laser-therapy-case-control-study-in-dogs-with-sterile-pyogranulomatous-pododermatitis
#12
Roberta Perego, D Proverbio, A Zuccaro, E Spada
AIM: Low-level laser therapy (LLLT) is a therapeutic photobiostimulation with properties in reducing swelling, inflammation, and promoting tissue healing. The objective of this pilot study was to evaluate LLLT in sterile pyogranulomatous pododermatitis in five dogs. MATERIALS AND METHODS: In each dog, one lesion was designated as the control (treated with a 0.0584% hydrocortisone aceponate spray), and one or more other lesions were treated with a gallium aluminum arsenide-laser, daily for 5 days...
August 2016: Veterinary World
https://www.readbyqxmd.com/read/27649282/the-chemokines-secretion-and-the-oxidative-stress-are-targets-of-low-level-laser-therapy-in-allergic-lung-inflammation
#13
Jorge Luis Costa Carvalho, Auriléia Aparecida de Brito, Ana Paula Ligeiro de Oliveira, Hugo Caire de Castro Faria Neto, Thiago Martini Pereira, Regiane Albertini de Carvalho, Elen Anatriello, Flávio Aimbire
Recent studies show that low-level laser therapy (LLLT) has an important anti-inflammatory action in acute lung inflammation. The present work explored if laser therapy is able to antagonize eosinophils and allergic inflammation induced by oxidative stress in Balb/c mice. Forty-eight hours after challenge, the leukocyte counting, ROS and nitrite/nitrate level, RANTES, CCL3, CCL8 as well as eotaxins were measured in the bronchoalveolar lavage fluid (BALF) of laser-treated mice or not. Into the lung, some chemokines receptors, the iNOS activity and mRNA expression, and the activities of superoxide dismutase (SOD), catalase, gluthatione, NADPH oxidase activities and thiobarbituric acid reactive species (T-Bars) were measured...
December 2016: Journal of Biophotonics
https://www.readbyqxmd.com/read/27627685/low-level-laser-therapy-and-cryotherapy-as-mono-and-adjunctive-therapies-for-achilles-tendinopathy-in-rats
#14
Sturla Haslerud, Rodrigo Alvaro Brandão Lopes-Martins, Lúcio Frigo, Jan Magnus Bjordal, Rodrigo Labat Marcos, Ingvill Fjell Naterstad, Liv Heide Magnussen, Jon Joensen
BACKGROUND AND OBJECTIVE: Low-level laser therapy (LLLT) and cryotherapy are widely used treatments in the acute phase of tendon injury. The aim of this study was to investigate the interaction of these two treatments on tendon inflammation and mechanical properties. MATERIALS AND METHODS: Six groups of six Wistar rats were used in this study. The Achilles tendons of the healthy control group were not subjected to injury or treatment. The tendons of the injured nontreated group (ING) were injured, but not treated...
January 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27590454/evaluation-of-low-level-laser-at-auriculotherapy-points-to-reduce-postoperative-pain-in-inferior-third-molar-surgery-study-protocol-for-a-randomized-controlled-trial
#15
Hélio Sampaio-Filho, Juliane Sotto-Ramos, Erika Horácio Pinto, Marcia Regina Cabral, Priscila Larcher Longo, Isabel Peixoto Tortamano, Rodrigo Labat Marcos, Daniela Fátima Teixeira Silva, Christine Pavani, Anna Carolina Ratto Tempestini Horliana
BACKGROUND: A comfortable postoperative return to daily activities has increased the need to control inflammation after third molar surgery. Anti-inflammatory drugs and analgesics are not exempt from adverse effects such as allergies and chronic gastritis, and they are not without cost. The association between low-level laser and auricular acupuncture can be an alternative when conventional drugs are contraindicated. Among its advantages, we can mention the low risk of side effects, low cost and simplicity of application...
September 2, 2016: Trials
https://www.readbyqxmd.com/read/27575834/pre-exercise-infrared-low-level-laser-therapy-810%C3%A2-nm-in-skeletal-muscle-performance-and-postexercise-recovery-in-humans-what-is-the-optimal-dose-a-randomized-double-blind-placebo-controlled-clinical-trial
#16
Adriane Aver Vanin, Thiago De Marchi, Shaiane Silva Tomazoni, Olga Tairova, Heliodora Leão Casalechi, Paulo de Tarso Camillo de Carvalho, Jan Magnus Bjordal, Ernesto Cesar Leal-Junior
AIM: This study aimed to evaluate the medium-term effects of low-level laser therapy (LLLT or photobiomodulation) in postexercise skeletal muscle recovery and performance enhancement and to identify the optimal dose of 810 nm LLLT. MATERIALS AND METHODS: A randomized, double-blind, placebo-controlled trial was performed, with voluntary participation of 28 high-level soccer athletes. We analyzed maximum voluntary contraction (MVC), delayed onset muscle soreness (DOMS), creatine kinase (CK) activity, and interleukin-6 (IL-6) expression...
October 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27426042/effect-of-low-level-laser-therapy-on-pain-and-perineal-healing-after-episiotomy-a-triple-blind-randomized-controlled-trial
#17
Marina B Alvarenga, Sonia Maria Junqueira Vasconcellos de Oliveira, Adriana A Francisco, Flora Maria B da Silva, Marcelo Sousa, Moacyr Roberto Nobre
BACKGROUND AND OBJECTIVE: Episiotomy is associated with perineal pain and healing complications. The low-level laser therapy (LLLT) reduces pain and inflammation and stimulates the healing process. This study aimed to assess the effect of LLLT on pain and perineal healing after an episiotomy. DESIGN/MATERIALS AND METHODS: A randomized, triple-blind, parallel clinical trial with 54 postpartum women who had a spontaneous birth with a right mediolateral episiotomy...
July 18, 2016: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/27251645/retinopathy-of-prematurity-therapeutic-strategies-based-on-pathophysiology
#18
Rowena Cayabyab, Rangasamy Ramanathan
Retinopathy of prematurity (ROP) continues to be a major preventable cause of blindness and visual handicaps globally. With improved perinatal care, improved survival of moderately preterm infants, and limited resources for oxygen delivery and monitoring, more mature preterm infants are developing severe ROP in developing countries. The pathophysiology of ROP is characterized by two phases. Phase I ROP is due to vaso-obliteration beginning immediately after birth secondary to a marked decrease in vascular endothelial growth factor (VEGF) and insulin-like growth factor-1 (IGF-1)...
2016: Neonatology
https://www.readbyqxmd.com/read/27135012/low-level-laser-therapy-in-the-treatment-of-intra-osseous-defect-a-case-report
#19
Smiti Bhardwaj, Joann Pauline George, Divakaran Remigus, Divya Khanna
Low level laser has been documented in literature to promote wound healing by reducing postoperative inflammation, oedema and reduces pain. This case report demonstrates the safe and positive outcome of LLLT in conjunction with demineralised bone matrix of bovine origin in the surgical treatment of a periodontal infrabony defect. After surgical defect debridement, low level semiconductor diode laser (GaAlAr) was delivered for 5 minutes to the inner margins of flap in contact mode and the defect was irradiated with LLLT in a non-contact mode for 10 minutes...
March 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27082031/short-and-medium-term-effects-of-low-level-laser-therapy-on-periodontal-status-in-lingual-orthodontic-patients
#20
Rosa Abellán, Clara Gómez, María Dolores Oteo, Giuseppe Scuzzo, Juan Carlos Palma
OBJECTIVE: The purpose of this study was to evaluate the short- and medium-term effects of low-level laser therapy (LLLT) applied in repeated doses in adults with a healthy periodontium treated by lingual orthodontic appliances. BACKGROUND DATA: Plaque accumulation, in combination with difficulty in removing it in lingual orthodontic patients, can cause gingival inflammation. METHODS: Twelve orthodontic patients scheduled for fixed lingual orthodontic treatment were selected...
July 2016: Photomedicine and Laser Surgery
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