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low level laser therapy inflammation

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https://www.readbyqxmd.com/read/27924419/beneficial-effect-of-low-level-laser-therapy-in-acute-lung-injury-after-i-i-r-is-dependent-on-the-secretion-of-il-10-and-independent-of-the-tlr-myd88-signaling
#1
J L Carvalho, A Britto, A P Ligeiro de Oliveira, H Castro-Faria-Neto, R Albertini, E Anatriello, F Aimbire
The use of low-level laser for lung inflammation treatment has been evidenced in animal studies as well as clinical trials. The laser action mechanism seems to involve downregulation of neutrophil chemoattractants and transcription factors. Innate immune responses against microorganisms may be mediated by toll-like receptors (TLR). Intestinal ischemia and reperfusion (i-I/R) lead to bacterial product translocation, such as endotoxin, which consequently activates TLRs leading to intestinal and lung inflammation after gut trauma...
December 6, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27913970/radiological-and-biochemical-effects-ctx-ii-mmp-3-8-and-13-of-low-level-laser-therapy-lllt-in-chronic-osteoarthritis-in-al-kharj-saudi-arabia
#2
Gopal Nambi S, Walid Kamal, Julie George, Elbagir Manssor
Inflammation of synovial membrane and degeneration of articular cartilage in osteoarthritis (OA) lead to major changes in joint space width (JSW) and biochemical components such as collagen-II telopeptide (CTX-II) and matrix metallo protineases (MMP-3, 8, and 13). Low-level laser therapy (LLLT) is thought to have an analgesic effect as well as biomodulatory effect on microcirculation and cartilage regeneration in animal studies. The objective of this study was to examine the analgesic and biochemical effect of LLLT in patients with knee osteoarthritis...
December 3, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27861614/photobiomodulation-with-pulsed-and-continuous-wave-near-infrared-laser-810-nm-al-ga-as-augments-dermal-wound-healing-in-immunosuppressed-rats
#3
Gaurav K Keshri, Asheesh Gupta, Anju Yadav, Sanjeev K Sharma, Shashi Bala Singh
Chronic non-healing cutaneous wounds are often vulnerable in one or more repair phases that prevent normal healing and pose challenges to the use of conventional wound care modalities. In immunosuppressed subject, the sequential stages of healing get hampered, which may be the consequences of dysregulated or stagnant wound inflammation. Photobiomodulation (PBM) or low-level laser (light) therapy (LLLT) emerges as a promising drug-free, non-invasive biophysical approach for promoting wound healing, reduction of inflammation, pain and restoration of functions...
2016: PloS One
https://www.readbyqxmd.com/read/27851931/combined-therapy-using-low-level-laser-and-chitosan-policaju-hydrogel-for-wound-healing
#4
Adelmo C Aragão-Neto, Paulo A G Soares, Maria H M Lima-Ribeiro, Elaine J A Carvalho, Maria T S Correia, Maria G Carneiro-da-Cunha
We have evaluated the effect of POLI-CHI hydrogel based on policaju (POLI) from cashew tree (Anacardium occidentale L.) gum and chitosan (CHI), associated or not with Low level laser therapy (LLLT), in wound healing. Sixty male Wistar rats were assigned into four groups: POLI-CHI hydrogel (H); LLLT (L); POLI-CHI with LLLT (HL) and saline control (C). Macroscopic evaluations were carried out using clinical observations and area measurements, as well as microscopic analysis by histological criteria. H and HL presented more esthetical scar tissue and larger wound contraction compared to C...
November 13, 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27815990/low-level-laser-therapy-for-beta-amyloid-toxicity-in-rat-hippocampus
#5
Yujiao Lu, Ruimin Wang, Yan Dong, Donovan Tucker, Ningjun Zhao, Md Ejaz Ahmed, Ling Zhu, Timon Cheng-Yi Liu, Robert M Cohen, Quanguang Zhang
Beta amyloid (Aβ) is well accepted to play a central role in the pathogenesis of Alzheimer's disease (AD). The present work evaluated the therapeutic effects of low-level laser irradiation (LLI) on Aβ-induced neurotoxicity in rat hippocampus. Aβ 1-42 was injected bilaterally to the hippocampus CA1 region of adult male rats, and 2-minute daily LLI treatment was applied transcranially after Aβ injection for 5 consecutive days. LLI treatment suppressed Aβ-induced hippocampal neurodegeneration and long-term spatial and recognition memory impairments...
October 11, 2016: Neurobiology of Aging
https://www.readbyqxmd.com/read/27813716/effects-of-low-level-laser-therapy-in-orthodontic-patients-on-immediate-inflammatory-response-after-mini-implants-insertion-a-preliminary-report
#6
Mario S Yanaguizawa, Selly S Suzuki, Elizabeth F Martinez, Hideo Suzuki, Maria Cristina J Pelegrin, Aguinaldo S Garcez
BACKGROUND: The primary stability of a mini-implant is crucial to treatment sequence since most orthodontic mini-implant failures occur at an early stage. Irritation or inflammation of peri-implant tissues has been related to decreasing mini-implant success. PURPOSE: This study evaluates the effect of low-level laser therapy on initial inflammation after orthodontic mini-implants installation. METHODS: Ten volunteers received two mini-implants (1...
November 3, 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27704296/photodynamic-therapy-decrease-immune-inflammatory-mediators-levels-during-periodontal-maintenance
#7
Priscila Vivas da Cruz Andrade, Vanessa Tubero Euzebio Alves, Verônica Franco de Carvalho, Michelle De Franco Rodrigues, Claudio Mendes Pannuti, Marinella Holzhausen, Giorgio De Micheli, Marina Clemente Conde
Antimicrobial photodynamic therapy (aPDT) was introduced as a promising adjuvant therapy on the periodontal treatment. The aim of this study was to evaluate the effect of aPDT on inflammatory mediator levels in residual periodontal pockets of patients with severe chronic periodontitis under periodontal maintenance, during 12 months follow-up. A randomized controlled trial study was conducted in 28 patients with severe chronic periodontitis. After non-surgical periodontal treatment, patients with at least four teeth with residual pocket probing depth (PPD) ≥4 mm were randomly assigned to either aPDT or control group...
October 4, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27651678/low-level-laser-therapy-case-control-study-in-dogs-with-sterile-pyogranulomatous-pododermatitis
#8
Roberta Perego, D Proverbio, A Zuccaro, E Spada
AIM: Low-level laser therapy (LLLT) is a therapeutic photobiostimulation with properties in reducing swelling, inflammation, and promoting tissue healing. The objective of this pilot study was to evaluate LLLT in sterile pyogranulomatous pododermatitis in five dogs. MATERIALS AND METHODS: In each dog, one lesion was designated as the control (treated with a 0.0584% hydrocortisone aceponate spray), and one or more other lesions were treated with a gallium aluminum arsenide-laser, daily for 5 days...
August 2016: Veterinary World
https://www.readbyqxmd.com/read/27649282/the-chemokines-secretion-and-the-oxidative-stress-are-targets-of-low-level-laser-therapy-in-allergic-lung-inflammation
#9
Jorge Luis Costa Carvalho, Auriléia Aparecida de Brito, Ana Paula Ligeiro de Oliveira, Hugo Caire de Castro Faria Neto, Thiago Martini Pereira, Regiane Albertini de Carvalho, Elen Anatriello, Flávio Aimbire
Recent studies show that low-level laser therapy (LLLT) has an important anti-inflammatory action in acute lung inflammation. The present work explored if laser therapy is able to antagonize eosinophils and allergic inflammation induced by oxidative stress in Balb/c mice. Forty-eight hours after challenge, the leukocyte counting, ROS and nitrite/nitrate level, RANTES, CCL3, CCL8 as well as eotaxins were measured in the bronchoalveolar lavage fluid (BALF) of laser-treated mice or not. Into the lung, some chemokines receptors, the iNOS activity and mRNA expression, and the activities of superoxide dismutase (SOD), catalase, gluthatione, NADPH oxidase activities and thiobarbituric acid reactive species (T-Bars) were measured...
September 20, 2016: Journal of Biophotonics
https://www.readbyqxmd.com/read/27627685/low-level-laser-therapy-and-cryotherapy-as-mono-and-adjunctive-therapies-for-achilles-tendinopathy-in-rats
#10
Sturla Haslerud, Rodrigo Alvaro Brandão Lopes-Martins, Lúcio Frigo, Jan Magnus Bjordal, Rodrigo Labat Marcos, Ingvill Fjell Naterstad, Liv Heide Magnussen, Jon Joensen
BACKGROUND AND OBJECTIVE: Low-level laser therapy (LLLT) and cryotherapy are widely used treatments in the acute phase of tendon injury. The aim of this study was to investigate the interaction of these two treatments on tendon inflammation and mechanical properties. MATERIALS AND METHODS: Six groups of six Wistar rats were used in this study. The Achilles tendons of the healthy control group were not subjected to injury or treatment. The tendons of the injured nontreated group (ING) were injured, but not treated...
September 14, 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27590454/evaluation-of-low-level-laser-at-auriculotherapy-points-to-reduce-postoperative-pain-in-inferior-third-molar-surgery-study-protocol-for-a-randomized-controlled-trial
#11
Hélio Sampaio-Filho, Juliane Sotto-Ramos, Erika Horácio Pinto, Marcia Regina Cabral, Priscila Larcher Longo, Isabel Peixoto Tortamano, Rodrigo Labat Marcos, Daniela Fátima Teixeira Silva, Christine Pavani, Anna Carolina Ratto Tempestini Horliana
BACKGROUND: A comfortable postoperative return to daily activities has increased the need to control inflammation after third molar surgery. Anti-inflammatory drugs and analgesics are not exempt from adverse effects such as allergies and chronic gastritis, and they are not without cost. The association between low-level laser and auricular acupuncture can be an alternative when conventional drugs are contraindicated. Among its advantages, we can mention the low risk of side effects, low cost and simplicity of application...
September 2, 2016: Trials
https://www.readbyqxmd.com/read/27575834/pre-exercise-infrared-low-level-laser-therapy-810%C3%A2-nm-in-skeletal-muscle-performance-and-postexercise-recovery-in-humans-what-is-the-optimal-dose-a-randomized-double-blind-placebo-controlled-clinical-trial
#12
Adriane Aver Vanin, Thiago De Marchi, Shaiane Silva Tomazoni, Olga Tairova, Heliodora Leão Casalechi, Paulo de Tarso Camillo de Carvalho, Jan Magnus Bjordal, Ernesto Cesar Leal-Junior
AIM: This study aimed to evaluate the medium-term effects of low-level laser therapy (LLLT or photobiomodulation) in postexercise skeletal muscle recovery and performance enhancement and to identify the optimal dose of 810 nm LLLT. MATERIALS AND METHODS: A randomized, double-blind, placebo-controlled trial was performed, with voluntary participation of 28 high-level soccer athletes. We analyzed maximum voluntary contraction (MVC), delayed onset muscle soreness (DOMS), creatine kinase (CK) activity, and interleukin-6 (IL-6) expression...
October 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27426042/effect-of-low-level-laser-therapy-on-pain-and-perineal-healing-after-episiotomy-a-triple-blind-randomized-controlled-trial
#13
Marina B Alvarenga, Sonia Maria Junqueira Vasconcellos de Oliveira, Adriana A Francisco, Flora Maria B da Silva, Marcelo Sousa, Moacyr Roberto Nobre
BACKGROUND AND OBJECTIVE: Episiotomy is associated with perineal pain and healing complications. The low-level laser therapy (LLLT) reduces pain and inflammation and stimulates the healing process. This study aimed to assess the effect of LLLT on pain and perineal healing after an episiotomy. DESIGN/MATERIALS AND METHODS: A randomized, triple-blind, parallel clinical trial with 54 postpartum women who had a spontaneous birth with a right mediolateral episiotomy...
July 18, 2016: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/27251645/retinopathy-of-prematurity-therapeutic-strategies-based-on-pathophysiology
#14
Rowena Cayabyab, Rangasamy Ramanathan
Retinopathy of prematurity (ROP) continues to be a major preventable cause of blindness and visual handicaps globally. With improved perinatal care, improved survival of moderately preterm infants, and limited resources for oxygen delivery and monitoring, more mature preterm infants are developing severe ROP in developing countries. The pathophysiology of ROP is characterized by two phases. Phase I ROP is due to vaso-obliteration beginning immediately after birth secondary to a marked decrease in vascular endothelial growth factor (VEGF) and insulin-like growth factor-1 (IGF-1)...
2016: Neonatology
https://www.readbyqxmd.com/read/27135012/low-level-laser-therapy-in-the-treatment-of-intra-osseous-defect-a-case-report
#15
Smiti Bhardwaj, Joann Pauline George, Divakaran Remigus, Divya Khanna
Low level laser has been documented in literature to promote wound healing by reducing postoperative inflammation, oedema and reduces pain. This case report demonstrates the safe and positive outcome of LLLT in conjunction with demineralised bone matrix of bovine origin in the surgical treatment of a periodontal infrabony defect. After surgical defect debridement, low level semiconductor diode laser (GaAlAr) was delivered for 5 minutes to the inner margins of flap in contact mode and the defect was irradiated with LLLT in a non-contact mode for 10 minutes...
March 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27082031/short-and-medium-term-effects-of-low-level-laser-therapy-on-periodontal-status-in-lingual-orthodontic-patients
#16
Rosa Abellán, Clara Gómez, María Dolores Oteo, Giuseppe Scuzzo, Juan Carlos Palma
OBJECTIVE: The purpose of this study was to evaluate the short- and medium-term effects of low-level laser therapy (LLLT) applied in repeated doses in adults with a healthy periodontium treated by lingual orthodontic appliances. BACKGROUND DATA: Plaque accumulation, in combination with difficulty in removing it in lingual orthodontic patients, can cause gingival inflammation. METHODS: Twelve orthodontic patients scheduled for fixed lingual orthodontic treatment were selected...
July 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27058019/effects-of-photobiomodulation-and-mesenchymal-stem-cells-on-articular-cartilage-defects-in-a-rabbit-model
#17
Reza Fekrazad, Mohamadreza Baghaban Eslaminejad, Arman M Shayan, Katayoun A M Kalhori, Fatemeh Mashhadi Abbas, Leila Taghiyar, Mir Sepehr Pedram, Mostafa Sadeghi Ghuchani
OBJECTIVE: The aim of this study was to evaluate the effectiveness of the application of cultured autologous bone marrow mesenchymal stem cells (BMSCs) with scaffold and low-level laser therapy (LLLT) on the repair of articular cartilage defects in rabbits. BACKGROUND DATA: For healing of the articular cartilage defects, although positive effects of BMSCs and LLLT have been demonstrated, their combination effect is still unknown; therefore, we investigated combining these two techniques has a synergistic effect...
April 8, 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/26989758/review-of-transcranial-photobiomodulation-for-major-depressive-disorder-targeting-brain-metabolism-inflammation-oxidative-stress-and-neurogenesis
#18
REVIEW
Paolo Cassano, Samuel R Petrie, Michael R Hamblin, Theodore A Henderson, Dan V Iosifescu
We examined the use of near-infrared and red radiation (photobiomodulation, PBM) for treating major depressive disorder (MDD). While still experimental, preliminary data on the use of PBM for brain disorders are promising. PBM is low-cost with potential for wide dissemination; further research on PBM is sorely needed. We found clinical and preclinical studies via PubMed search (2015), using the following keywords: "near-infrared radiation," "NIR," "low-level light therapy," "low-level laser therapy," or "LLLT" plus "depression...
July 2016: Neurophotonics
https://www.readbyqxmd.com/read/26984240/low-level-laser-therapy-photobiomodulation-in-the-management-of-side-effects-of-chemoradiation-therapy-in-head-and-neck-cancer-part-1-mechanisms-of-action-dosimetric-and-safety-considerations
#19
REVIEW
Judith A E M Zecha, Judith E Raber-Durlacher, Raj G Nair, Joel B Epstein, Stephen T Sonis, Sharon Elad, Michael R Hamblin, Andrei Barasch, Cesar A Migliorati, Dan M J Milstein, Marie-Thérèse Genot, Liset Lansaat, Ron van der Brink, Josep Arnabat-Dominguez, Lisette van der Molen, Irene Jacobi, Judi van Diessen, Jan de Lange, Ludi E Smeele, Mark M Schubert, René-Jean Bensadoun
PURPOSE: There is a large body of evidence supporting the efficacy of low level laser therapy (LLLT), more recently termed photobiomodulation (PBM), for the management of oral mucositis (OM) in patients undergoing radiotherapy for head and neck cancer (HNC). Recent advances in PBM technology, together with a better understanding of mechanisms involved, may expand the applications for PBM in the management of other complications associated with HNC treatment. This article (part 1) describes PBM mechanisms of action, dosimetry, and safety aspects and, in doing so, provides a basis for a companion paper (part 2) which describes the potential breadth of potential applications of PBM in the management of side-effects of (chemo)radiation therapy in patients being treated for HNC and proposes PBM parameters...
June 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/26942449/pepito-driven-pedf-expression-ameliorates-diabetic-retinopathy-hallmarks
#20
Sofia M Calado, Francisco Diaz-Corrales, Gabriela A Silva
Diabetic retinopathy (DR) is one of the major complications of diabetes mellitus. It is characterized by retinal microvascular changes caused by chronic exposure to hyperglycemia, leading to low tissue oxygenation and ultimately to neovascularization. Laser photocoagulation and vitrectomy are the most efficient treatments for DR, but display severe side effects such as the destruction of the healthy retina. Another clinical approach uses antiangiogenic agents to prevent and delay progression of neovascularization, but these require recurrent local administrations that increase the possibility of retinal detachment, vitreous hemorrhage, and cataract formation...
April 2016: Human Gene Therapy Methods
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