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low level laser therapy inflammation

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https://www.readbyqxmd.com/read/29909435/photobiomodulation-therapy-pbmt-on-acute-pain-and-inflammation-in-patients-who-underwent-total-hip-arthroplasty-a-randomized-triple-blind-placebo-controlled-clinical-trial
#1
Luciana Gonçalves Langella, Heliodora Leão Casalechi, Shaiane Silva Tomazoni, Douglas Scott Johnson, Regiane Albertini, Rodney Capp Pallotta, Rodrigo Labat Marcos, Paulo de Tarso Camillo de Carvalho, Ernesto Cesar Pinto Leal-Junior
When conservative treatments fail, hip osteoarthritis (OA), a chronic degenerative disease characterized by cartilage wear, progressive joint deformity, and loss of function, can result in the need for a total hip arthroplasty (THA). Surgical procedures induced tissue trauma and incite an immune response. Photobiomodulation therapy (PBMt) using low-level laser therapy (LLLT) and/or light-emitting diode therapy (LEDT) has proven effective in tissue repair by modulating the inflammatory process and promoting pain relief...
June 16, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29890728/photobiomodulation-therapy-pbmt-in-peripheral-nerve-regeneration-a-systematic-review
#2
REVIEW
Marcelie Priscila de Oliveira Rosso, Daniela Vieira Buchaim, Natália Kawano, Gabriela Furlanette, Karina Torres Pomini, Rogério Leone Buchaim
Photobiomodulation therapy (PBMT) has been investigated because of its intimate relationship with tissue recovery processes, such as on peripheral nerve damage. Based on the wide range of benefits that the PBMT has shown and its clinical relevance, the aim of this research was to carry out a systematic review of the last 10 years, ascertaining the influence of the PBMT in the regeneration of injured peripheral nerves. The search was performed in the PubMed/MEDLINE database with the combination of the keywords: low-level laser therapy AND nerve regeneration...
June 9, 2018: Bioengineering
https://www.readbyqxmd.com/read/29725945/low-level-laser-irradiation-modifies-the-effect-of-hyperglycemia-on-adhesion-molecule-levels
#3
Krzysztof Góralczyk, Justyna Szymańska, Łukasz Gryko, Jacek Fisz, Danuta Rość
Endothelium plays a key role in maintaining vascular homeostasis by secreting active factors involved in many biological processes such as hemostasis, angiogenesis, and inflammation. Hyperglycemia in diabetic patients causes dysfunction of endothelial cells. Soluble fractions of adhesion molecules like sE-selectin and vascular cell adhesion molecule (sVCAM) are considered as markers of endothelial damage. The low-level laser therapy (LLLT) effectively supports the conventional treatment of vascular complications in diabetes, for example hard-to-heal wounds in patients with diabetic foot syndrome...
May 3, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29686745/low-level-laser-therapy-reduces-lung-inflammation-in-an-experimental-model-of-chronic-obstructive-pulmonary-disease-involving-p2x7-receptor
#4
Gabriel da Cunha Moraes, Luana Beatriz Vitoretti, Auriléia Aparecida de Brito, Cintia Estefano Alves, Nicole Cristine Rigonato de Oliveira, Alana Dos Santos Dias, Yves Silva Teles Matos, Manoel Carneiro Oliveira-Junior, Luis Vicente Franco Oliveira, Renata Kelly da Palma, Larissa Carbonera Candeo, Adriana Lino-Dos-Santos-Franco, Anna Carolina Ratto Tempestine Horliana, João Antonio Gimenes Júnior, Flavio Aimbire, Rodolfo Paula Vieira, Ana Paula Ligeiro-de-Oliveira
Chronic obstructive pulmonary disease (COPD) is a progressive disease characterized by irreversible airflow limitation, airway inflammation and remodeling, and enlargement of alveolar spaces. COPD is in the top five leading causes of deaths worldwide and presents a high economic cost. However, there are some preventive measures to lower the risk of developing COPD. Low-level laser therapy (LLLT) is a new effective therapy, with very low cost and no side effects. So, our objective was to investigate if LLLT reduces pulmonary alterations in an experimental model of COPD...
2018: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29578836/protective-effects-of-photobiomodulation-against-resistance-exercise-induced-muscle-damage-and-inflammation-in-rats
#5
Helenita Antonia de Oliveira, Ednei Luiz Antonio, Flávio André Silva, Paulo de Tarso Camillo de Carvalho, Regiane Feliciano, Amanda Yoshizaki, Stella de Souza Vieira, Brunno Lemes de Melo, Ernesto Cesar Pinto Leal-Junior, Rodrigo Labat, Danilo Sales Bocalini, José Antonio Silva Junior, Paulo José Ferreira Tucci, Andrey Jorge Serra
We investigated whether low-level laser therapy (LLLT) prior to or post resistance exercise could attenuate muscle damage and inflammation. Female Wistar rats were assigned to non-LLLT or LLLT groups. An 830-nm DMC Laser Photon III was used to irradiate their hind legs with 2J, 4J, and 8J doses. Irradiations were performed prior to or post (4J) resistance exercise bouts. Resistance exercise consisted of four maximum load climbs. The load work during a resistance exercise bout was similar between Control (non-LLLT, 225 ± 10 g), 2J (215 ± 8 g), 4J (210 ± 9 g), and 8J (226 ± 9 g) groups...
March 26, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29577710/etiological-periodontal-treatment-with-and-without-low-level-laser-therapy-on-il-1%C3%AE-level-in-gingival-crevicular-fluid-an-in-vivo-multicentric-pilot-study
#6
F Mastrangelo, A Dedola, F Cattoni, F Ferrini, F Bova, M Tatullo, E Gherlone, L Lo Muzio
Cytokine proteins may have important roles during different human physiological and pathological processes. In the oral cavity, the bone loss and periodontal tissue pathology was related to inflammatory process activation. The aim of the present study was to assess the effects of etiological periodontal therapy with and without the use of Low Level Laser Therapy (LLLT) on clinical periodontal parameters and interleukin (IL)-1β level in gingival crevicular fluid (GCF) from chronic periodontitis (CP) patients...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29477473/quercetin-and-low-level-laser-therapy-promote-wound-healing-process-in-diabetic-rats-via-structural-reorganization-and-modulatory-effects-on-inflammation-and-oxidative-stress
#7
Osama M Ahmed, Tarek Mohamed, Hala Moustafa, Hany Hamdy, Rasha R Ahmed, Ebtsam Aboud
This study aimed to evaluate the effect of quercetin and the photo-stimulatory effect of low energy 632.8 nm laser irradiation on excisional wound healing in non-diabetic and diabetic rats. Streptozotocin (45 mg/kg body weight) was intraperitoneally applied for diabetes induction. A full-thickness skin wound (2 × 2 cm2 ) was aseptically created with a scalpel in non-diabetic and diabetic rats on the shaved back of the animals. The wounded non-diabetic and diabetic rats were treated every other day with quercetin by oral gavage at dose 25 mg/kg body weight and/or with low level laser therapy (LLLT) for 14 days...
May 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29473115/the-effects-of-exercise-training-associated-with-low-level-laser-therapy-on-biomarkers-of-adipose-tissue-transdifferentiation-in-obese-women
#8
Raquel Munhoz da Silveira Campos, Ana Raimunda Dâmaso, Deborah Cristina Landi Masquio, Fernanda Oliveira Duarte, Marcela Sene-Fiorese, Antonio Eduardo Aquino, Filippo Aragão Savioli, Pamela Cristina Lopes Quintiliano, Ana Claudia Pelissari Kravchychyn, Liliane Isabel Guimarães, Lian Tock, Lila Missae Oyama, Valter Tadeu Boldarine, Vanderlei Salvador Bagnato, Nivaldo Antonio Parizotto
Investigations suggest the benefits of low-level laser therapy (LLLT) to improve noninvasive body contouring treatments, inflammation, insulin resistance and to reduce body fat. However, the mechanism for such potential effects in association with exercise training (ET) and possible implications in browning adiposity processes remains unclear. Forty-nine obese women were involved, aged between 20 and 40 years with a body mass index (BMI) of 30-40 kg/m2 . The volunteers were divided into Phototherapy (808 nm) and SHAM groups...
February 23, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29138594/prevention-and-treatment-of-acute-and-chronic-radiodermatitis
#9
Sophie Seité, René-Jean Bensadoun, Jean-Michel Mazer
More than half the number of patients with cancer, who are treated with radiotherapy, will have radiodermatitis at some point during their treatment. Radiodermatitis either occurs early on in the treatment period or appears months or up to several years later. Acute radiodermatitis is a burn injury that varies in severity according to both treatment and inherent patient factors. Most acute radiodermatitis reactions resolve after several weeks but some reactions persist and can cause complications. Late-onset radiodermatitis is characterized by telangiectasia that forms on atrophic and fragile skin...
2017: Breast Cancer: Targets and Therapy
https://www.readbyqxmd.com/read/29116611/anti-inflammatory-effects-of-low-level-laser-therapy-on-human-periodontal-ligament-cells-in-vitro-study
#10
Ji-Hua Lee, Min-Hsuan Chiang, Ping-Ho Chen, Mei-Ling Ho, Huey-Er Lee, Yan-Hsiung Wang
Periodontal disease is a chronic inflammatory disease that is commonly treated with surgical and nonsurgical techniques. However, both approaches have limitations. Low-level laser therapy (LLLT) has been widely applied in reducing inflammatory reactions, and research indicates that LLLT induces an anti-inflammatory effect that may enhance periodontal disease therapy. The purpose of this study was to investigate the anti-inflammatory effect of LLLT on human periodontal ligament cells (hPDLCs) in an inflammatory environment and aimed to determine the possible mechanism of action...
April 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29107204/laser-photobiomodulation-of-pro-inflammatory-mediators-on-walker-tumor-256-induced-rats
#11
Maria Carla Petrellis, Lúcio Frigo, Rodrigo Labat Marcos, Rodney Capp Pallotta, Maria Helena Catelli de Carvalho, Marcelo Nicolás Muscará, Durvanei Augusto Maria, Rodrigo Álvaro Brandão Lopes-Martins
Laser photobiomodulation or low-level laser therapy (LLLT) is recognized worldwide for its expansive use in medicine. LLLT has been reported to increase enzymatic activity, increasing the mitochondrial transmembrane potential, leading to an increased energy availability and signal transduction. Nevertheless, an inhibitory effect is also observed by the production of excessive ROS which can result the shutdown of mitochondrial energy production, and finally to apoptosis. However, the mechanism of apoptosis induced by LLLT is still not well understood...
December 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29099680/pre-exercise-infrared-photobiomodulation-therapy-810%C3%A2-nm-in-skeletal-muscle-performance-and-postexercise-recovery-in-humans-what-is-the-optimal-power-output
#12
Adriano Rodrigues de Oliveira, Adriane Aver Vanin, Shaiane Silva Tomazoni, Eduardo Foschini Miranda, Gianna Móes Albuquerque-Pontes, Thiago De Marchi, Vanessa Dos Santos Grandinetti, Paulo Roberto Vicente de Paiva, Treice Beatriz Gonçalves Imperatori, Paulo de Tarso Camillo de Carvalho, Jan Magnus Bjordal, Ernesto Cesar Pinto Leal-Junior
BACKGROUND: Photobiomodulation therapy (PBMT) has recently been used to alleviate postexercise muscle fatigue and enhance recovery, demonstrating positive results. A previous study by our research group demonstrated the optimal dose for an infrared wavelength (810 nm), but the outcomes could be optimized further with the determination of the optimal output power. OBJECTIVE: The aim of the present study was to evaluate the effects of PBMT (through low-level laser therapy) on postexercise skeletal muscle recovery and identify the best output power...
November 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29098460/low-level-laser-therapy-prevents-endothelial-cells-from-tnf-%C3%AE-cycloheximide-induced-apoptosis
#13
Yu-Hsiu Chu, Shu-Ya Chen, Yueh-Ling Hsieh, Yi-Hsien Teng, Yu-Jung Cheng
Low-level laser therapy (LLLT), widely used in physiotherapy, has been known to enhance wound healing and stimulate cell proliferation, including fibroblast and endothelial cells. Applying LLLT can increase cell proliferation in many kinds of cells including fibroblasts and endothelial cells. However, the protective mechanisms of LLLT on endothelial apoptosis remain unclear. We hypothesized LLLT can protect endothelial cells from inflammation-induced apoptosis. Human endothelial cell line, EA.hy926 cells, and TNF-α/cycloheximide (TNF/CHX) were used to explore the protective effects of LLLT (660 nm) on inflammation-induced endothelial apoptosis...
February 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29095531/low-level-red-led-light-inhibits-hyperkeratinization-and-inflammation-induced-by-unsaturated-fatty-acid-in-an-in-vitro-model-mimicking-acne
#14
Wen-Hwa Li, Ali Fassih, Curt Binner, Ramine Parsa, Michael D Southall
BACKGROUND AND OBJECTIVE: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous units (PSU), associated with increased sebum production, abnormal follicular keratinization (hyperkeratinization), follicular overgrowth of Propionibacterium acnes (P. acnes), and increased inflammatory mediator release. Light therapy has attracted medical interests as a safe alternative treatment for acne. Both blue and red light therapies at high doses >10 J/cm2 have demonstrated marked effects on inflammatory acne lesions...
February 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29060675/effect-of-laser-diode-light-irradiation-on-growth-capability-of-human-hair-follicle-dermal-papilla-cells
#15
S Jampa-Ngern, K Viravaidya-Pasuwat, S Suvanasuthi, A Khantachawana
Low level laser therapy is widely used to relieve pain and inflammation, and to restore cellular functions. The photons of light are absorbed by mitochondria in cells, leading to an increase in the production of adenosine triphosphate (ATP), nitric oxide release, blood flow, and reactive oxygen species (ROS). This study proposed the use of a laser diode array at 808 nm to stimulate the proliferation and to activate the functions of dermal papilla cells, which were an important part of the hair growth cycle...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28935484/effects-of-low-level-laser-therapy-and-platelet-concentrate-on-bone-repair-histological-histomorphometric-immunohistochemical-and-radiographic-study
#16
Thiago Hoffman Jonasson, Rafael Zancan, Lucas de Oliveira Azevedo, Ana Claudia Fonseca, Marcela Claudino da Silva, Allan Fernando Giovanini, João Cesar Zielak, Melissa Rodrigues de Araujo
PURPOSE: Low-level laser therapy (LLLT) can increase bone metabolism, cell proliferation, and maturation, and reduce inflammation, while platelet concentrate (PC) assists bone healing process by releasing proteins and growth factors. Here, we evaluated the efficacy of combined LLLT and PC therapy in the healing of critical-size bone defects. MATERIALS AND METHODS: Calvarial critical-size defects 5 mm in diameter were made in 48 Wistar rats. Bones were removed, milled, and used as autogenous bone grafts...
August 19, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28931981/immunomodulatory-effects-of-two-different-physical-therapy-modalities-in-patients-with-chronic-obstructive-pulmonary-disease
#17
Sherin Hassan M Mehani
[Purpose] Counteracting the systemic cytokine release and its inflammatory effects by improving respiratory muscle strength and controlling lung inflammation may be important for improving immune system in patients with chronic obstructive pulmonary disease, So the aim of the present study was to evaluate the effect of low level laser therapy and inspiratory muscle training on interleukin-6 (IL-6) as a marker of inflammation and CD4+/CD8+ ratio as a marker for T Lymphocytes in these patients. [Subjects and Methods] Forty male patients with stable COPD participated in the study, their ages ranged between 55-65 years...
September 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28863395/comparison-of-repeated-applications-of-apdt-with-amoxicillin-and-metronidazole-in-the-treatment-of-chronic-periodontitis-a-short-term-study
#18
RANDOMIZED CONTROLLED TRIAL
Letícia Helena Theodoro, Alessandra Barreto Lopes, Marta Aparecida Alberton Nuernberg, Marina Módolo Cláudio, Daniela Maria Janjacomo Miessi, Márcio Luiz Ferro Alves, Cristiane Duque, Andrea Mombelli, Valdir Gouveia Garcia
AIM: The aim of this study was to compare the clinical effects of Metronidazole (MTZ) combined with Amoxicillin (AMX) and repeated applications of antimicrobial photodynamic therapy (aPDT) as an adjuvant for the treatment of chronic periodontitis. METHODS: A double-blind controlled and randomized clinical trial was conducted in 34 patients. All of the patients were treated with scaling and root planing (SRP) and separated into 2 groups: the MTZ+AMX Group (n=17), who received SRP and the systemic use of MTZ (400mg 3×per day for 7days) and AMX (500mg 3×per day for 7days), and the aPDT Group (n=17), who received SRP and three aPDT applications at all sites with a probing depth≥5mm immediately, at 48 and 96h after scaling and placebo pills over the span of 7days...
September 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28823073/effect-of-low-level-laser-therapy-%C3%AE-780-nm-on-the-mechanically-damaged-dentin-pulp-complex-in-a-model-of-extrusive-luxation-in-rat-incisors
#19
Dandara Andrade de Santana, Gabriela Ferraz Fonseca, Luciana Maria Pedreira Ramalho, Tânia Tavares Rodriguez, Marcio Cajazeira Aguiar
In order to regenerate the dental pulp, many strategies have been developed as phototherapy. In the pulp repair, we do not know if gallium-aluminum-arsenide (GaAlAs) laser preserves the primary odontoblasts or stimulates the formation of more dentin matrix when dental pulp is damaged. The aim of the present study was to examine the effect of laser phototherapy (λ780 nm) on vascularization, inflammation, density of the primary odontoblast layer, and formation of reactionary and reparative dentin in the dental pulp by provoking extrusion of the rat incisor...
December 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28748217/mechanisms-and-applications-of-the-anti-inflammatory-effects-of-photobiomodulation
#20
Michael R Hamblin
Photobiomodulation (PBM) also known as low-level level laser therapy is the use of red and near-infrared light to stimulate healing, relieve pain, and reduce inflammation. The primary chromophores have been identified as cytochrome c oxidase in mitochondria, and calcium ion channels (possibly mediated by light absorption by opsins). Secondary effects of photon absorption include increases in ATP, a brief burst of reactive oxygen species, an increase in nitric oxide, and modulation of calcium levels. Tertiary effects include activation of a wide range of transcription factors leading to improved cell survival, increased proliferation and migration, and new protein synthesis...
2017: AIMS Biophysics
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