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https://www.readbyqxmd.com/read/29460159/management-of-esophageal-food-impaction-varies-among-gastroenterologists-and-affects-identification-of-eosinophilic-esophagitis
#1
Girish Hiremath, Michael F Vaezi, Sandeep K Gupta, Sari Acra, Evan S Dellon
BACKGROUND AND AIMS: Esophageal food impaction (EFI) is a gastrointestinal emergency requiring immediate evaluation in the emergency room (ER) and an esophagogastroduodenoscopy (EGD) for disimpaction. EFI is also a distinct presenting feature of eosinophilic esophagitis (EoE). This study aimed at understanding the management of EFI among gastroenterologists (GIs) and estimated its impact on identification of EoE in USA. METHODS: GIs associated with three major gastroenterology societies based in USA were invited to participate in a web-based survey...
February 20, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29455418/preoperative-chemotherapy-with-docetaxel-cisplatin-and-5-fluorouracil-for-locally-advanced-esophageal-carcinosarcoma-a-case-report-and-review-of-the-literature
#2
Tomoko Yoshimoto, Shinichiro Kobayashi, Kengo Kanetaka, Kazuma Kobayashi, Yasuhiro Nagata, Michi Morita, Yuriko Isagawa, Naoe Kinoshita, Mitsuhisa Takatsuki, Susumu Eguchi
BACKGROUND: Esophageal carcinosarcoma is a relatively rare malignant neoplasm composed of both epithelial carcinomatous and mesenchymal sarcomatous elements. There is no recommended clinical treatment for esophageal carcinosarcoma because of the rarity of the disease. This report describes a case of esophageal carcinosarcoma that was effectively treated with docetaxel, cisplatin, and 5-fluorouracil as preoperative chemotherapy. CASE PRESENTATION: A 73-year-old man had a chief complaint of dysphagia with epigastric pain...
February 17, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29434119/a-case-of-helicobacter-pylori-negative-advanced-gastric-cancer-with-massive-eosinophilia
#3
Atsushi Takagi, Hideki Ozawa, Masayuki Oki, Hidetaka Yanagi, Kazuhito Nabeshima, Naoto Nakamura
The incidence of Helicobacter pylori-negative gastric cancer is very low. A 60-year-old man was referred to Tokai University Hospital from a local clinic because of eosinophilia. The laboratory data revealed prominent eosinophilia, with a white blood cell count of 7,900/μl and increased eosinophil granulocyte level of 1,659/μl. After an examination for secondary eosinophilia, esophagogastroduodenoscopy showed an enlarged gastric fold in the corpus, suggesting type 4 gastric cancer. Repeated EGD and a re-biopsy demonstrated poorly differentiated adenocarcinoma and signet ring cell carcinoma...
February 9, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29427732/risk-of-oral-and-upper-gastrointestinal-cancers-in-persons-with-positive-results-from-a-fecal-immunochemical-test-in-a-colorectal-cancer-screening-program
#4
Manon van der Vlugt, Esmée J Grobbee, Patrick M Bossuyt, Amanda C R K Bos, Ernst J Kuipers, Iris Lansdorp-Vogelaar, Manon C W Spaander, Evelien Dekker
BACKGROUND & AIMS: European guidelines recommend screening for colorectal cancer (CRC) using the fecal immunochemical test (FIT), with follow-up colonoscopies for individuals with positive test results. However, more than half of participants with positive results from the FIT are not found to have advanced neoplasia in the colonoscopy examination. Fecal occult blood might also come from the upper gastrointestinal (GI) tract, so perhaps we should consider esophagogastroduodenoscopy (EGD), to detect upper GI cancers...
February 7, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29423432/complications-and-outcomes-of-routine-endoscopy-in-the-very-elderly
#5
Ryoichi Miyanaga, Naoki Hosoe, Makoto Naganuma, Kenro Hirata, Seiichiro Fukuhara, Yoshihiro Nakazato, Keisuke Ojiro, Eisuke Iwasaki, Naohisa Yahagi, Haruhiko Ogata, Takanori Kanai
Background and study aims: In Japan, the elderly population has been increasing annually. The number of elderly patients for whom esophagogastroduodenoscopy (EGD) and colonoscopy (CS) is indicated also has been rising. The aim of this study was to evaluate the safety and efficacy of routine endoscopy in a cohort of octogenarians aged 85 years and older - defined by the World Health Organization as the very elderly. Patients and methods: A total of 5,586 patients underwent EGDs, and 2,484 patients underwent CSs performed at the Keio University Hospital from January to September 2014...
February 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29422678/clinical-translation-of-tethered-confocal-microscopy-capsule-for-unsedated-diagnosis-of-eosinophilic-esophagitis
#6
Nima Tabatabaei, DongKyun Kang, Minkyu Kim, Tao Wu, Catriona N Grant, Mireille Rosenberg, Norman S Nishioka, Paul E Hesterberg, John Garber, Qian Yuan, Aubrey J Katz, Guillermo J Tearney
Esophagogastroduodenoscopy (EGD) is a widely used procedure, posing significant financial burden on both healthcare systems and patients. Moreover, EGD is time consuming, sometimes difficult to tolerate, and suffers from an imperfect diagnostic yield as the limited number of collected biopsies does not represent the whole organ. In this paper, we report on technological and clinical feasibility of a swallowable tethered endomicroscopy capsule, which is administered without sedation, to image large regions of esophageal and gastric mucosa at the cellular level...
February 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29399617/outcomes-of-anterior-myotomy-versus-posterior-myotomy-during-poem-a-randomized-pilot-study
#7
Mohan Ramchandani, Zaheer Nabi, D Nageshwar Reddy, Rahul Talele, Santosh Darisetty, Rama Kotla, Radhika Chavan, Manu Tandan
Background and study aims:  Peroral endoscopic myotomy (POEM) can be performed via an anterior or posterior approach, depending on the operator's preference. Data are lacking on comparative outcomes of both approaches. Patients and methods:  This is a pilot randomized study comparing endoscopic anterior and posterior myotomy during POEM in patients with Achalasia cardia (AC). Patients were randomized into 2 groups (n = 30 in each group); anterior myotomy group (AG) and posterior myotomy group (PG) and were followed at 1, 3 and 6 months after POEM...
February 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29398864/laser-assisted-lip-repositioning-surgery-novel-approach-to-treat-gummy-smile
#8
Sana Farista, Ramreddy Yeltiwar, Butchibabu Kalakonda, Kaustubh Suresh Thakare
Excessive gingival display (EGD) resulting in a "gummy smile" is a major esthetic concern with ramifications in an individual's personal and social life. Numerous treatment modalities have been used for the correction of EGD. The present case report describes the successful treatment of a young woman with an excess gingival display caused by a hyperactive upper lip and a mild vertical maxillary excess that was treated with a laser-assisted lip repositioning surgical technique accompanied by gingival recontouring...
March 2017: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29394742/-a-case-of-duodenal-cancer-with-familial-adenomatous-polyposis
#9
Takafumi Yachi, Taiichi Wakiya, Keinosuke Ishido, Daisuke Kudo, Norihisa Kimura, Kenichi Hakamada
A 34-year-old man was diagnosed with familial adenomatous polyposis(FAP)in September 2011, and he underwent endoscopic mucosal resection(EMR)due to multiple polyps in the duodenum and small intestine. Three months later, duodenal cancer was found, and he underwent a subsequent EMR. The pathological findings showed residual cancer cells in the lateral margin; therefore, EMR was performed again. Total colectomy and partial resection of the small intestine was performed in December 2012. Esophagogastroduodenoscopy(EGD)was then performed every 3-6 months, and EMR was performed 4 times...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394663/-a-case-of-advanced-gastric-cancer-with-liver-metastasis-treated-by-curative-surgery-after-chemotherapy-using-s-1-plus-oxaliplatin
#10
Tsutomu Namikawa, Yasuhio Kawanishi, Yuki Fujieda, Kazune Fujisawa, Eri Munekage, Masaya Munekage, Hiromichi Maeda, Hiroyuki Kitagawa, Michiya Kobayashi, Kazuhiro Hanazaki
A 76-year-old man was referred to our hospital with gastric cancer.Esophagogastroduodenoscopy (EGD)revealed an irregular, nodulated lesion with ulcers in the lower part of the stomach, for which biopsy specimens indicated poorly differentiated adenocarcinoma.Abdominal computed tomography(CT)showed a well-defined mass lesion measuring 5.3 cm in the posterior segment of the liver.Under the clinical diagnosis of advanced gastric cancer with liver metastasis, the patient received chemotherapy using S-1 and oxaliplatin...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29390283/a-case-report-of-gastric-linitis-plastica-diagnosed-by-endoscopic-ultrasound-guided-fine-needle-aspiration
#11
Shinji Muraoka, Kouhei Tsuchida, Mari Iwasaki, Naoya Izawa, Hidehito Jinnai, Toshinori Komatsubara, Misako Tsunemi, Fumi Sakuma, Ken Kashima, Ko Fukushi, Hideyuki Hiraishi
RATIONALE: There is currently no consensus on the ideal method for obtaining deep tissue biopsy material of advanced gastric LP. EUS-FNA has potential as a useful diagnostic method. Thus, we report the case of a 46-year-old male with advanced gastric linitis plastica (LP) who was diagnosed using endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). PATIENT CONCERNS: The patient underwent esophagogastroduodenoscopy (EGD) because of epigastric pain at a local clinic...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29380175/combined-and-alternating-topical-steroids-and-food-elimination-diet-for-the-treatment-of-eosinophilic-esophagitis
#12
Craig C Reed, Anca M Safta, Shadi Qasem, M Angie Almond, Evan S Dellon, Elizabeth T Jensen
BACKGROUND: Few studies have examined combined or alternating treatment algorithms in eosinophilic esophagitis. AIMS: We conducted a retrospective cohort study to ascertain the efficacy and adherence to a combined and alternating treatment approach with topical corticosteroids and 2-food elimination diet for pediatric EoE. METHODS: Patients were prescribed a 2-food elimination diet (milk and soy) and topical corticosteroid (fluticasone or oral viscous budesonide) for 3 months, after which the steroid was discontinued and 2-food elimination diet continued for 3 months...
January 29, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29379535/diagnostic-yield-of-esophagogastroduodenoscopy-in-children-with-chronic-abdominal-pain
#13
Ulas Emre Akbulut, Hamdi Cihan Emeksiz, Fatma Gulgun Kocak, Ayten Livaoglu
Introduction: Chronic abdominal pain (CAP) is one of the most common indications of esophagogastroduodenoscopy (EGD) in the pediatric population. However, there is not enough information about the diagnostic yield of EGD in children with CAP. We aimed to evaluate the diagnostic yield of EGD in children with CAP in the Eastern Black Sea region of Turkey. Material and methods: The study included children (n = 372) who underwent EGD for the primary indication of chronic abdominal pain during an 18-month period...
January 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29375739/case-series-on-multimodal-endoscopic-therapy-for-gastric-antral-vascular-ectasia-a-tertiary-center-experience
#14
Tasnia Matin, Mohammed Naseemuddin, Mohamed Shoreibah, Peng Li, Kondal Kyanam Kabir Baig, Charles Mel Wilcox, Shajan Peter
AIM: To study and describe patients who underwent treatment for gastric antral vascular ectasia (GAVE) with different endoscopic treatment modalities. METHODS: We reviewed patients with GAVE who underwent treatment at University of Alabama at Birmingham between March 1, 2012 and December 31, 2016. Included patients had an endoscopic diagnosis of GAVE with associated upper gastrointestinal bleeding or iron deficiency anemia. RESULTS: Seven out of 15 patients had classic watermelon description for GAVE, 1/15 with diffuse/honeycomb pattern and 6/15 with nodular GAVE per EGD description...
January 16, 2018: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29368943/a-rare-mass-in-the-duodenal-bulb-brunner-s-glands-cystadenoma
#15
Ting Guo, Yuyong Tan, Deliang Liu
A 56-year-old man referred to our department for treatment of a mass in the duodenal bulb. Esophagogastroduodenoscopy(EGD) showed a large spherical mass extending from the pyloric canal to the anterior wall of the duodenal bulb.The patient received endoscopic submucosal dissection uneventfully.Histology demonstrated Brunner's glands csytadenoma finally.
January 25, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29356236/isolation-and-characterization-of-heterotrophic-nitrifying-and-aerobic-denitrifying-klebsiella-pneumoniae-and-klebsiella-variicola-strains-from-various-environments
#16
Yong Feng, Jie Feng, Qinglong Shu
AIMS: We sought to isolate novel heterotrophic nitrifying and aerobic denitrifying Klebsiella pneumoniae (K. pneumoniae) and Klebsiella variicola (K. variicola) strains from various natural environments and characterize their nitrogen removal processes. METHODS AND RESULTS: Ten novel Klebsiella strains with heterotrophic nitrification and aerobic denitrification abilities, including seven K. pneumoniae and three K. variicola, were successfully isolated from feces, sewage, plant surfaces and sludge...
January 21, 2018: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29351773/treatment-of-long-segment-barrett-s-adenocarcinoma-by-complete-circular-endoscopic-submucosal-dissection-a-case-report
#17
Miki Kaneko, Akira Mitoro, Motoyuki Yoshida, Masayoshi Sawai, Yasushi Okura, Masanori Furukawa, Tadashi Namisaki, Kei Moriya, Takemi Akahane, Hideto Kawaratani, Mitsuteru Kitade, Kousuke Kaji, Hiroaki Takaya, Yasuhiko Sawada, Kenichiro Seki, Shinya Sato, Tomomi Fujii, Junichi Yamao, Chiho Obayashi, Hitoshi Yoshiji
BACKGROUND: We present the first description of en bloc endoscopic submucosal dissection (ESD) for total circumferential Barrett's adenocarcinoma, predominantly of the long-segment Barrett's esophagus (LSBE), with a 2-year follow-up and management strategies for esophageal stricture prevention. CASE PRESENTATION: A 59-year-old man was diagnosed with LSBE and Barrett's adenocarcinoma by esophagogastroduodenoscopy (EGD). A 55-mm-long circumferential tumor was completely resected by ESD...
January 19, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29350673/glyphosate-ingestion-causing-multiple-organ-failure-a-near-fatal-case-report
#18
Edoardo Picetti, Michela Generali, Francesca Mensi, Giampaolo Neri, Roberta Damia, Giuseppe Lippi, Gianfranco Cervellin
A 55 years old man self-presented to our Emergency Department (ED) reporting an attempted suicide by cutting the left forearm veins and ingesting approximately 200 mL of an herbicide (Myrtos®, containing 36% of glyphosate as isopropylamine salt). Laboratory tests showed metabolic acidosis. Hydration with normal saline and alkalinization with sodium bicarbonate was started according to suggestion of the poison control center, since an antidote was unavailable. Cardiorespiratory condition gradually worsened, so that non-invasive positive pressure ventilation (NIPPV) was applied and infusion of fluids was established...
January 16, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29327262/risk-of-neoplastic-progression-among-patients-with-an-irregular-z-line-on-long-term-follow-up
#19
David Itskoviz, Zohar Levi, Doron Boltin, Alex Vilkin, Yifat Snir, Rachel Gingold-Belfer, Yaron Niv, Iris Dotan, Ram Dickman
BACKGROUND: Barrett's esophagus (BE) is a known complication of gastroesophageal reflux disease. In a previous study, we described a high prevalence of intestinal metaplasia (IM) in patients with an irregular Z line. However, the clinical importance of this finding is unclear. GOALS: To evaluate the long-term development of BE and relevant complications in patients diagnosed with an irregular Z line, with or without IM, on routine esophago-gastro-duodenoscopy (EGD)...
January 11, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29320565/the-absence-of-n-acetylglucosamine-in-wall-teichoic-acids-of-listeria-monocytogenes-modifies-biofilm-architecture-and-tolerance-to-rinsing-and-cleaning-procedures
#20
Thomas Brauge, Christine Faille, Irina Sadovskaya, Alain Charbit, Thierry Benezech, Yang Shen, Martin J Loessner, Jean Romain Bautista, Graziella Midelet-Bourdin
The wall teichoic acid (WTA) is the major carbohydrate found within the extracellular matrix of the Listeria monocytogenes biofilm. We first addressed the frequency of spontaneous mutations in two genes (lmo2549 and lmo2550) responsible for the GlcNAcylation in 93 serotype 1/2a strains that were mainly isolated from seafood industries. We studied the impact of mutations in lmo2549 or lmo2550 genes on biofilm formation by using one mutant carrying a natural mutation inactivating the lmo2550 gene (DSS 1130 BFA2 strain) and two EGD-e mutants that lack respective genes by in-frame deletion of lmo2549 or lmo2550 using splicing-by-overlap-extension PCR, followed by allelic exchange mutagenesis...
2018: PloS One
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