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adult spinal deformities

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https://www.readbyqxmd.com/read/27921035/genetics-underlying-an-individualized-approach-to-adult-spinal-disorders
#1
REVIEW
Corey T Walker, Phillip A Bonney, Nikolay L Martirosyan, Nicholas Theodore
Adult spinal disorders are a significant cause of morbidity across the world and carry significant health and economic burdens. Genetic predispositions are increasingly considered for these conditions and are becoming understood. Advances in molecular technologies since the mid-1990s have made possible genetic characterizations of these diseases in many populations, and recent findings have provided insight into the underlying pathophysiologic mechanisms. These studies have made clear the genetic heterogeneity producing clinical phenotypes and suggest that individualized treatments are possible in the future...
2016: Frontiers in Surgery
https://www.readbyqxmd.com/read/27911226/letter-to-the-editor-adult-spinal-deformity-surgery-is-it-always-worthwhile
#2
Enrico Tessitore, Oliver P Gautschi
No abstract text is available yet for this article.
December 2, 2016: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/27902557/stiffness-after-pan-lumbar-arthrodesis-for-adult-spinal-deformity-does-not-significantly-impact-patient-functional-status-or-satisfaction-irrespective-of-proximal-endpoint
#3
Robert A Hart, Jayme Hiratzka, Marie S Kane, Virginie Lafage, Eric Klineberg, Christopher P Ames, Breton G Line, Frank Schwab, Justin K Scheer, Shay Bess, D Kojo Hamilton, Christopher I Shaffrey, Greg Mundis, Justin S Smith, Douglas C Burton, Daniel M Sciubba, Vedat Deviren, Oheneba Boachie-Adjei
STUDY DESIGN: Prospective, multi-center OBJECTIVE.: To determine if stiffness significantly affects function or satisfaction after pan-lumbar arthrodesis. SUMMARY OF BACKGROUND DATA: The Lumbar Stiffness Disability Index (LSDI) is a validated measure of the effect of lumbar stiffness on functional activities. Data suggests that patients undergoing fusion of the entire lumbar spine are at greatest risk of functional limitations from stiffness. METHODS: The LSDI, Short Form 36 (SF-36), Scoliosis Research Society-22 (SRS-22), and Oswestry Disability Index (ODI) were administered pre-operatively and at 2-year minimum follow-up to 103 spinal deformity patients from 11 centers...
November 29, 2016: Spine
https://www.readbyqxmd.com/read/27890439/a-japanese-nationwide-multicenter-survey-on-perioperative-complications-of-corrective-fusion-for-elderly-patients-with-adult-spinal-deformity
#4
Yu Yamato, Yukihiro Matsuyama, Kazuhiro Hasegawa, Yoichi Aota, Tsutomu Akazawa, Takahiro Iida, Kazumasa Ueyama, Koki Uno, Tokumi Kanemura, Noriaki Kawakami, Toshiaki Kotani, Masashi Takaso, Jun Takahashi, Masato Tanaka, Hiroshi Taneichi, Taichi Tsuji, Hideo Hosoe, Joji Mochida, Takachika Shimizu, Ikuho Yonezawa, Kota Watanabe, Morio Matsumoto
BACKGROUND: Recently, corrective fusion surgery for patients with adult spinal deformity (ASD) has become common in Japan. This study aimed to clarify the status of surgeries for ASD in Japan, focusing on perioperative complications. A nationwide multicenter survey gathering information on surgically treated ASD patients was conducted by the committee for Adult Spinal Deformity of the Japanese Scoliosis Society. METHODS: This study was a review of retrospectively collected data from 18 spine scoliosis centers belonging to the Japanese Scoliosis Society...
November 24, 2016: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/27884745/increase-in-spinal-deformity-patients-in-patients-age-60-and-over-is-not-associated-with-increased-complications
#5
David C Sing, Sigurd H Berven, Shane Burch, Lionel N Metz
BACKGROUND CONTEXT: Surgical treatment for adult spinal deformity improves patient quality of life; however trends in surgical utilization in the elderly, whom may be at higher risk for complications, remain unclear. PURPOSE: To identify trends in the utilization of adult deformity and determine complication rates among older patients. STUDY DESIGN/SETTING: Retrospective database analysis. PATIENT SAMPLE: The Nationwide Inpatient Sample database was queried from 2004 to 2011 to identify adult patients who underwent spinal fusion of 8 or more levels using ICD-9 coding...
November 21, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27879571/radiographic-predictors-for-mechanical-failure-following-adult-spinal-deformity-surgery-a-retrospective-cohort-study-in-138-patients
#6
Dennis Winge Hallager, Sven Karstensen, Naeem Bukhari, Martin Gehrchen, Benny Dahl
STUDY DESIGN: Retrospective cohort study at a single institution. OBJECTIVE: We aimed at estimating the rate of revision procedures and identify radiographic predictors of mechanical failure following adult spinal deformity surgery. SUMMARY OF BACKGROUND DATA: Mechanical failure rates following adult spinal deformity surgery range 12% to 37% in literature. While the importance of spinal and spino-pelvic alignment is well documented for surgical outcome and ideal alignment has been proposed as sagittal vertical axis (SVA) < 5 cm, pelvic tilt < 20° and lumbar lordosis (LL) = pelvic incidence ± 9°, the role of radiographic sagittal spine parameters and alignment targets as predictors for mechanical failure remains uncertain...
November 22, 2016: Spine
https://www.readbyqxmd.com/read/27875416/comparison-of-structural-disease-burden-to-health-related-quality-of-life-scores-in-264-adult-spinal-deformity-patients-with-2-year-follow-up-novel-insights-into-drivers-of-disability
#7
Joshua Bakhsheshian, Justin K Scheer, Jeffrey L Gum, Lance Horner, Richard Hostin, Virginie Lafage, Shay Bess, Themistocles S Protopsaltis, Douglas C Burton, Malla Keefe, Robert A Hart, Gregory M Mundis, Christopher I Shaffrey, Frank Schwab, Justin S Smith, Christopher P Ames
STUDY DESIGN: This is a review of a prospective multicenter database. OBJECTIVE: To investigate the relationship between preoperative disability and sagittal deformity in patients with high Oswestry Disability Index (ODI) and no sagittal malalignment, or low ODI and high sagittal malalignment. SUMMARY OF BACKGROUND DATA: The relationship between ODI and sagittal malalignment varies between each adult spinal deformity (ASD) patient. METHODS: A prospective multicenter database of 365 patients with ASD undergoing surgical reconstruction was analyzed...
November 21, 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27864681/are-sagittal-spinopelvic-radiographic-parameters-significantly-associated-with-quality-of-life-of-adult-spinal-deformity-patients-multivariate-linear-regression-analyses-for-pre-operative-and-short-term-post-operative-health-related-quality-of-life
#8
Mitsuru Takemoto, Louis Boissière, Jean-Marc Vital, Ferran Pellisé, Francisco Javier Sanchez Perez-Grueso, Frank Kleinstück, Emre R Acaroglu, Ahmet Alanay, Ibrahim Obeid
PURPOSE: To evaluate the association in ASD patients between spinopelvic sagittal parameters and health-related quality of life (HRQL), adjusted for demographic and surgical variables. METHODS: We constructed multiple linear regression models to investigate pre-operative (PreOp) and 6-month post-operative (PostOp) HRQL as assessed by the Oswestry Disability Index (ODI), with sagittal parameters as independent variables adjusted for potential confounders, such as age, sex, body mass index, past spine surgery, types of surgical treatment, and complications...
November 18, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27857857/predictive-parameters-for-the-antecedent-development-of-hip-pathology-associated-with-long-segment-fusions-to-the-pelvis-for-the-treatment-of-adult-spinal-deformity
#9
Merritt D Kinon, Rani Nasser, Jonathan P Nakhla, Owoicho Adogwa, Jessica R Moreno, Michael Harowicz, Terence Verla, Reza Yassari, Carlos A Bagley
BACKGROUND: The surgical treatment of adult scoliosis frequently involves long segment fusions across the lumbosacral joints that redistribute tremendous amounts of force to the remaining mobile spinal segments as well as to the pelvis and hip joints. Whether or not these forces increase the risk of femoral bone pathology remains unknown. The aim of this study is to determine the correlation between long segment spinal fusions to the pelvis and the antecedent development of degenerative hip pathologies as well as what predictive patient characteristics, if any, correlate with their development...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27856380/t9-versus-t10-as-the-upper-instrumented-vertebra-for-correction-of-adult-deformity-rationale-and-recommendations
#10
Hwee Weng Dennis Hey, Kimberly-Anne Tan, Christabel Shao-En Neo, Eugene Tze-Chun Lau, Denise Ai-Wen Choong, Leok-Lim Lau, Gabriel Ka-Po Liu, Hee-Kit Wong
BACKGROUND CONTEXT: Adult spinal deformity correction sometimes involves long posterior pedicle screw constructs extending from the lumbosacral spine to the thoracic vertebra. As fusion obliterates motion and places supraphysiological stress on adjacent spinal segments, it is crucial to ascertain the ideal upper instrumented vertebra (UIV) to minimize risk of proximal junctional failure (PJF). The T10 vertebra is often chosen to allow bridging of the thoracolumbar junction into the immobile thoracic vertebrae on the basis that it is the lowest immobile thoracic vertebra strut by the rib cage...
November 14, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27852709/long-fusion-correction-of-degenerative-adult-spinal-deformity-and-the-selection-of-the-upper-or-lower-thoracic-region-as-the-site-of-proximal-instrumentation-a-systematic-review-and-meta-analysis
#11
Xin Fu, Xiao-Lei Sun, Jonathan A Harris, Sun-Ren Sheng, Hua-Zi Xu, Yong-Long Chi, Ai-Min Wu
OBJECTIVE: The aim of this study was to compare outcomes when the upper and lower thoracic regions were used as the site of proximal instrumentation to treat adult spinal deformity. METHODS: MEDLINE, Embase and Cochrane library searches were performed to identify studies that compared outcome measures when the upper and lower thoracic vertebrae (UTV and LTV, respectively) were used as the site of proximal instrumentation. The weighted mean difference (WMD) was calculated for continuous outcomes, and the relative risk (RR) was calculated for dichotomous outcomes...
November 15, 2016: BMJ Open
https://www.readbyqxmd.com/read/27852505/thirty-day-reoperation-and-readmission-rates-after-correction-of-adult-spinal-deformity-via-circumferential-minimally-invasive-surgery-analysis-of-a-7-year-experience
#12
Neel Anand, Zeeshan M Sardar, Andrea Simmonds, Babak Khandehroo, Sheila Kahwaty, Eli M Baron
STUDY DESIGN: Single-center retrospective analysis of consecutive patients who have undergone circumferential minimally invasive surgery (cMIS) for correction of adult spinal deformity (ASD). OBJECTIVES: To study the rates of reoperations and readmissions within the first 30 days following cMIS for correction of ASD. BACKGROUND: Hospital readmission and reoperation rates have been emphasized as an important measure of quality and cost-effectiveness of care...
January 2016: Spine Deformity
https://www.readbyqxmd.com/read/27832361/population-based-normative-data-for-the-scoliosis-research-society-22r-questionnaire-in-adolescents-and-adults-including-a-comparison-with-eq-5d
#13
Elias Diarbakerli, Anna Grauers, Paul Gerdhem
PURPOSE: The Scoliosis Research Society (SRS) 22r questionnaire is a widely used instrument. To estimate the disorder´s impact on quality of life and to gain knowledge about treatment effects, normative values are needed. METHODS: Individuals were randomly invited from the general population. 272 individuals (145 females) answered the SRS-22r and EuroQol 5-dimensions (EQ-5D) questionnaires and stratified according to sex and age; ≤19 years (n = 61), 20-39 years (n = 66), 40-59 years (n = 84) and ≥60 years (n = 61)...
November 10, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27831987/development-of-validated-computer-based-preoperative-predictive-model-for-proximal-junction-failure-pjf-or-clinically-significant-pjk-with-86-accuracy-based-on-510-asd-patients-with-2-year-follow-up
#14
Justin K Scheer, Joseph A Osorio, Justin S Smith, Frank Schwab, Virginie Lafage, Robert A Hart, Shay Bess, Breton Line, Bassel G Diebo, Themistocles S Protopsaltis, Amit Jain, Tamir Ailon, Douglas C Burton, Christopher I Shaffrey, Eric Klineberg, Christopher P Ames
STUDY DESIGN: A retrospective review of large, multicenter adult spinal deformity (ASD) database. OBJECTIVE: The aim of this study was to build a model based on baseline demographic, radiographic, and surgical factors that can predict clinically significant proximal junctional kyphosis (PJK) and proximal junctional failure (PJF). SUMMARY OF BACKGROUND DATA: PJF and PJK are significant complications and it remains unclear what are the specific drivers behind the development of either...
November 15, 2016: Spine
https://www.readbyqxmd.com/read/27831984/baseline-patient-reported-outcomes-correlate-weakly-with-radiographic-parameters-a-multicenter-prospective-nih-adult-symptomatic-lumbar-scoliosis-study-of-286-patients
#15
Todd M Chapman, Christine R Baldus, Jon D Lurie, Steven D Glassman, Frank J Schwab, Christopher I Shaffrey, Virginie Lafage, Oheneba Boachie-Adjei, Han J Kim, Justin S Smith, Charles H Crawford, Lawrence G Lenke, Jacob M Buchowski, Charles Edwards, Tyler Koski, Stefan Parent, Stephen Lewis, Daniel G Kang, Jamal McClendon, Lionel Metz, Lukas P Zebala, Michael P Kelly, Kevin F Spratt, Keith H Bridwell
STUDY DESIGN: Prospective, cross-sectional study. OBJECTIVE: The aim of the study was to determine which radiographic parameters drive patient-reported outcomes (PROs) in primary presentation adult symptomatic lumbar scoliosis (ASLS). SUMMARY OF BACKGROUND DATA: Previous literature suggests correlations between PROs and sagittal plane deformity (sagittal vertical axis [SVA], pelvic incidence-lumbar lordosis [PI-LL] mismatch, pelvic tilt [PT])...
November 15, 2016: Spine
https://www.readbyqxmd.com/read/27831967/5-year-reoperation-risk-and-causes-for-revision-after-idiopathic-scoliosis-surgery
#16
S Imraan Ahmed, Tracey P Bastrom, Burt Yaszay, Peter O Newton
STUDY DESIGN: Actuarial "survivorship" analysis OBJECTIVE.: To define the incidence and cause of surgical revision five years after scoliosis surgery. SUMMARY OF BACKGROUND DATA: Data on contemporary revision surgery rates after idiopathic scoliosis surgery beyond the two years postoperatively in the adolescent and young adult population is limited. METHODS: Patients enrolled in a prospective, multicenter, idiopathic scoliosis surgical registry from 1995-2009 were reviewed...
November 9, 2016: Spine
https://www.readbyqxmd.com/read/27817139/three-dimensional-reconstruction-using-stereoradiography-for-evaluating-adult-spinal-deformity-a-reproducibility-study
#17
Emmanuelle Ferrero, Renaud Lafage, Shaleen Vira, Pierre-Yves Rohan, Jonathan Oren, Edward Delsole, Pierre Guigui, Frank Schwab, Virginie Lafage, Wafa Skalli
PURPOSE: In addition to the sagittal alignment, impact of transverse plane parameters (TPP) and rotatory subluxation on patients reported outcomes were highlighted. One of the hypotheses for genesis of degenerative scoliosis is disc degeneration with increased axial vertebral (AVR) and intervertebral rotation (AIR). Therefore, TPP analysis at early stage of the scoliosis seems of particular interest. This study aims at assessing reliability of tridimensional (3D) reconstructions of adult spinal deformity (ASD) patients...
November 5, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27802254/t1-pelvic-angle-is-a-useful-parameter-for-postoperative-evaluation-in-adult-spinal-deformity-patients
#18
Tomohiro Banno, Tomohiko Hasegawa, Yu Yamato, Sho Kobayashi, Daisuke Togawa, Shin Oe, Yuki Mihara, Yukihiro Matsuyama
STUDY DESIGN: Retrospective review. OBJECTIVE: We investigated validity of T1 pelvic angle (TPA) for postoperative assessment and determined its target value for corrective scoliosis surgery. SUMMARY OF BACKGROUND DATA: TPA is a novel spinopelvic parameter accounting for both pelvic retroversion and trunk anteversion. As an angle, it is less affected by posture and correlates well with health-related quality of life in adult spinal deformity patients...
November 1, 2016: Spine
https://www.readbyqxmd.com/read/27785479/severe-progressive-scoliosis-in-an-adult-female-possibly-secondary-thoracic-surgery-in-childhood-treated-with-scoliosis-specific-schroth-physiotherapy-case-presentation
#19
Andrea Lebel, Victoria Ashley Lebel
BACKGROUND: Scoliosis is a complex three-dimensional (3D) spinal deformity. Acquired scoliosis in early childhood may progress into adulthood and pose an increased risk of health problems and reduction in quality of life. In Canada, patients with scoliosis are not referred for physiotherapeutic scoliosis-specific exercises (PSSE) despite the fact that Schroth physiotherapy, a scoliosis-specific 3D posture training and exercise program, can be effective in reducing pain and improving scoliosis curves, vital capacity, and overall quality of life in scoliosis patients...
2016: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/27775931/sublaminar-decompression-a-new-technique-for-spinal-canal-decompression-in-the-treatment-of-stenosis-in-degenerative-spinal-conditions
#20
Khaled M Kebaish, Benjamin D Elder, Sheng-Fu L Lo, Timothy F Witham
STUDY DESIGN: Technical report and case illustration. OBJECTIVE: To review the rationale and steps for a sublaminar decompression in the setting of adult deformity surgery and in degenerative spondylosis. SUMMARY OF BACKGROUND DATA: Several variations of lumbar laminotomy and posterior decompressions have been reported, although these are primarily in the setting of isolated lumbar stenosis, and often focus on treatment of central stenosis...
October 21, 2016: Clinical Spine Surgery
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