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Mariet Allen, Sarah J Lincoln, Morgane Corda, Jens O Watzlawik, Minerva M Carrasquillo, Joseph S Reddy, Jeremy D Burgess, Thuy Nguyen, Kimberly Malphrus, Ronald C Petersen, Neill R Graff-Radford, Dennis W Dickson, Nilüfer Ertekin-Taner
OBJECTIVE: To investigate and characterize putative "loss-of-function" (LOF) adenosine triphosphate-binding cassette, subfamily A member 7 (ABCA7) mutations reported to associate with Alzheimer disease (AD) risk. METHODS: We genotyped 6 previously reported ABCA7 putative LOF variants in 1,465 participants with AD, 381 participants with other neuropathologies (non-AD), and 1,043 controls and assessed the overall mutational burden for association with different diagnosis groups...
February 2017: Neurology. Genetics
Ali Dehghani, Nahid Dehghan Nayeri, Abbas Ebadi
BACKGROUND: Due to many physical and mental disorders that occur in multiple sclerosis patients, identifying the factors affecting coping based on the experiences of patients using qualitative study is essential to improve their quality of life. This study was conducted to explore the antecedents of coping with the disease in patients with multiple sclerosis. METHODS: This is a qualitative study conducted on 11 patients with multiple sclerosis in 2015 in Tehran, Iran...
January 2017: International Journal of Community Based Nursing and Midwifery
Andrea Liuzzo, Lincoln Gray, Matthew Wallace, Mark L Gabriele
No abstract text is available yet for this article.
January 14, 2017: Physiology & Behavior
Zachary Y Kerr, Andrew E Lincoln, Shane V Caswell, David A Klossner, Nina Walker, Thomas P Dompier
CONTEXT: Participation in collegiate women's lacrosse has increased dramatically, but little recent epidemiological data exists regarding injuries. OBJECTIVE: Describe the epidemiology of National Collegiate Athletic Association (NCAA) women's lacrosse injuries during the 2009-10 through 2014-15 academic years. SETTING: Aggregate injury and exposure data collected from 40 women's lacrosse programs providing 83 team-seasons of data. PATIENTS OR OTHER PARTICIPANTS: Collegiate women's lacrosse student-athletes...
January 17, 2017: Journal of Sport Rehabilitation
Marcel Riehle, Tania M Lincoln
BACKGROUND AND OBJECTIVES: The negative symptoms of schizophrenia are related to lower social functioning even in non-clinical samples, but little is known about the distinct social consequences of motivational and expressive negative symptoms. In this study we focused on expressive negative symptoms and examined how these symptoms and varying degrees of pro-social facial expressiveness (smiling and mimicry of smiling) relate to the social evaluations by face-to-face interaction partners and to social support...
January 10, 2017: Journal of Behavior Therapy and Experimental Psychiatry
Fabian Lamster, Tania M Lincoln, Clara M Nittel, Winfried Rief, Stephanie Mehl
Loneliness and paranoia are related, but the mechanisms that link them to each other remain unclear. Systematic reviews on loneliness propose a social-cognitive model in which loneliness leads to negative evaluations of other persons and a lack of interpersonal trust. However, the data discussed in these reviews are based on healthy individuals. Building on this model, the present study investigated 1) whether negative interpersonal schemata mediate the association between loneliness and paranoia and 2) whether a low level of perceived social support and less frequent social contact are related to loneliness...
January 2, 2017: Comprehensive Psychiatry
Carlo N De Cecco, U Joseph Schoepf, Lynne Steinbach, Daniel T Boll, W Dennis Foley, Ravi K Kaza, David N Bolus, Desiree E Morgan, Dushyant V Sahani, William P Shuman, Marilyn J Siegel, Terri J Vrtiska, Benjamin M Yeh, Lincoln L Berland
This is the third of a series of 4 white papers that represent Expert Consensus Documents developed by the Society of Computed Body Tomography and Magnetic Resonance through its Task Force on dual-energy computed tomography. This paper, part 3, describes computed tomography angiography and thoracic, cardiac, vascular, and musculoskeletal clinical applications. At the end of the discussion of each application category (vascular, cardiac, pulmonary, and musculoskeletal), we present our consensus opinions on the current clinical utility of the application and opportunities for further research...
January 2017: Journal of Computer Assisted Tomography
Gemma Giménez Papiol, Veronica Beuzenberg, Andrew I Selwood, Lincoln MacKenzie, Michael A Packer
A capture mechanism observed in a culture of the dinoflagellate Dinophysis acuta when preying on the ciliate Mesodinium rubrum (also sometimes referred to as Myrionecta rubra) is described. The dinoflagellate released cohesive clumps of mucilage into the culture media. When M. rubrum cells came into contact with this mucilage, they were immediately immobilized, but remained alive for a short period of time. Observations of D. acuta cells 'visiting and probing' trapped M. rubrum cells were made and at a critical point D...
September 2016: Harmful Algae
Sarah Hope Lincoln, Emily M Norkett, Katherine H Frost, Joseph Gonzalez-Heydrich, Eugene J D'Angelo
After participating in this activity, learners should be better able to:• Evaluate the evolution of social cognitive abilities as a developmental process• Assess the evidence regarding social cognition difficulties in youth at clinical high risk for psychosisIndividuals at clinical high risk (CHR) for psychosis exhibit a broad range of difficulties, including impaired social cognition, which may represent a target for early identification and intervention. Several studies have examined various domains of social cognition in CHR individuals...
January 2017: Harvard Review of Psychiatry
Maria van den Heuvel, Lincoln Jansz, Xianghu Xiong, Balraj Singhal
No abstract text is available yet for this article.
February 2017: American Journal of Physical Medicine & Rehabilitation
D T Tyler Flockhart, Lincoln P Brower, M Isabel Ramirez, Keith A Hobson, Leonard I Wassenaar, Sonia Altizer, D Ryan Norris
Addressing population declines of migratory insects requires linking populations across different portions of the annual cycle and understanding the effects of variation in weather and climate on productivity, recruitment, and patterns of long-distance movement. We used stable H and C isotopes and geospatial modeling to estimate the natal origin of monarch butterflies (Danaus plexippus) in eastern North America using over 1000 monarchs collected over almost four decades at Mexican overwintering colonies. Multinomial regression was used to ascertain which climate-related factors best-predicted temporal variation in natal origin across six breeding regions...
January 3, 2017: Global Change Biology
Roshan das Nair, Heather Cogger, Esme Worthington, Nadina B Lincoln
No abstract text is available yet for this article.
December 27, 2016: Stroke; a Journal of Cerebral Circulation
Dennis K M Ip, Lincoln L H Lau, Nancy H L Leung, Vicky J Fang, Kwok-Hung Chan, Daniel K W Chu, Gabriel M Leung, J S Malik Peiris, Timothy M Uyeki, Benjamin J Cowling
BACKGROUND: Influenza virus infections are associated with a wide spectrum of disease. However, few studies have investigated in detail the epidemiology and virology of asymptomatic and mild illness with influenza virus infections. METHODS: In a community-based study in Hong Kong from 2008 to 2014, we followed up initially healthy individuals who were household contacts of symptomatic persons with laboratory-confirmed influenza, to identify secondary infections...
December 22, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Kylie Gwynne, Debbie McCowen, Sally Cripps, Michelle Lincoln, Michelle Irving, Anthony Blinkhorn
BACKGROUND: Aboriginal people, and particularly those in rural areas, continue to suffer very high levels of dental disease despite significant reductions in the wider Australian population in the past 30 years. Until recently, there has been a shortage of oral health clinicians and the majority have provided care in major cities. The NSW Government funded various models of care for rural and regional areas and vulnerable population groups including Aboriginal people. This study utilises a comparative retrospective analysis to compare two models of oral health care for Aboriginal people including those living in rural NSW to inform future policy decisions...
December 23, 2016: Australian Dental Journal
Aline Gomes da Silva, Mário Fonseca Paulino, Lincoln da Silva Amorim, Edenio Detmann, Luciana Navajas Rennó, Márcio de Souza Duarte, Felipe Henrique de Moura, Luciano Prímola de Melo, Paulo Henrique Silva E Paiva, Marcos Rocha Manso, Victor Valério de Carvalho
Creep feeding has been used to reduce calves' nutritional dependence on the cow, but research results under tropical conditions have not been conclusive about the effects on the cow. Therefore, this study was conducted to evaluate the effects of high and low supplementation levels for Nellore heifer calves on performance, milk production, and metabolic profile of their mothers. Fifty multiparous Nellore cows and their respective calves were used. The following treatments were evaluated: 0-control, no supplement was fed to calves; 3-calves received supplement in the amount of 3 g/kg of body weight (BW); 6-calves received supplement in the amount of 6 g/kg of BW...
December 15, 2016: Tropical Animal Health and Production
R Lincoln, A M Durantini, L E Greene, S R Martínez, R Knox, M C Becerra, G Cosa
We report two BODIPY based photosensitizers (Br2BOAc and I2BOAc) featuring an acetoxymethyl substituent at the meso-position. These photosensitizers show improved photostability against singlet oxygen, when compared to a BODIPY photosensitizer lacking the acetoxymethyl group. Both compounds were evaluated for photodynamic therapy against HeLa cells and photodynamic inactivation against E. coli bacteria. We show that the compounds readily embed in the lipid membranes of HeLa cervical cancer cells and efficiently induced light-dependent apoptosis at nanomolar concentration...
December 14, 2016: Photochemical & Photobiological Sciences
Shirley A Thomas, Elizabeth Coates, Roshan das Nair, Nadina B Lincoln, Cindy Cooper, Rebecca Palmer, Stephen J Walters, Nicholas R Latimer, Timothy J England, Laura Mandefield, Timothy Chater, Patrick Callaghan, Avril E R Drummond
BACKGROUND: There is currently insufficient evidence for the clinical and cost-effectiveness of psychological therapies for treating post-stroke depression. METHODS/DESIGN: BEADS is a parallel group feasibility multicentre randomised controlled trial with nested qualitative research and economic evaluation. The aim is to evaluate the feasibility of undertaking a full trial comparing behavioural activation (BA) to usual stroke care for 4 months for patients with post-stroke depression...
2016: Pilot and Feasibility Studies
KunHo Yoon, Jae-Hyeok Lee, Joohoon Kang, Junmo Kang, Michael J Moody, Mark C Hersam, Lincoln J Lauhon
The decreasing cost of silicon-based photovoltaics has enabled significant increases in solar electricity generation worldwide. Silicon photoanodes could also play an important role in the cost-effective generation of solar fuels, but the most successful methods of photoelectrode passivation and performance enhancement rely on a combination of precious metals and sophisticated processing methods that offset the economic arguments for silicon. Here we show that metal-free carbon-based nanomaterial coatings deposited from solution can protect silicon photoanodes carrying out the oxygen evolution reaction in a range of working environments...
December 14, 2016: Nano Letters
Awatif M Abdulmajeed, Samantha R Derby, Samantha K Strickland, Mirwais M Qaderi
There is no information on variation of methane (CH4) emissions from plant organs exposed to multiple environmental factors. We investigated the interactive effects of temperature and ultraviolet-B (UVB) radiation on CH4 emissions from different organs of pea (Pisum sativum L. var. UT234 Lincoln). Plants were grown hydroponically under two temperatures (22/18°C and 28/24°C; 16h day/8h night) and two levels of UVB radiation [0 and 5kJm(-2) d(-1)] in controlled-environment growth chambers for ten days, after two weeks of initial growth under ambient temperatures...
January 2017: Journal of Photochemistry and Photobiology. B, Biology
Minerva M Carrasquillo, Mariet Allen, Jeremy D Burgess, Xue Wang, Samantha L Strickland, Shivani Aryal, Joanna Siuda, Michaela L Kachadoorian, Christopher Medway, Curtis S Younkin, Asha Nair, Chen Wang, Pritha Chanana, Daniel Serie, Thuy Nguyen, Sarah Lincoln, Kimberly G Malphrus, Kevin Morgan, Todd E Golde, Nathan D Price, Charles C White, Philip L De Jager, David A Bennett, Yan W Asmann, Julia E Crook, Ronald C Petersen, Neill R Graff-Radford, Dennis W Dickson, Steven G Younkin, Nilüfer Ertekin-Taner
INTRODUCTION: We hypothesized that common Alzheimer's disease (AD)-associated variants within the triggering receptor expressed on myeloid (TREM) gene cluster influence disease through gene expression. METHODS: Expression microarrays on temporal cortex and cerebellum from ∼400 neuropathologically diagnosed subjects and two independent RNAseq replication cohorts were used for expression quantitative trait locus analysis. RESULTS: A variant within a DNase hypersensitive site 5' of TREM2, rs9357347-C, associates with reduced AD risk and increased TREML1 and TREM2 levels (uncorrected P = 6...
December 8, 2016: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
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