keyword
https://read.qxmd.com/read/38196635/preliminary-impact-of-an-mhealth-education-and-social-support-intervention-on-maternal-health-knowledge-and-outcomes-among-postpartum-mothers-in-punjab-india
#1
Alison M El Ayadi, Nadia G Diamond-Smith, Mona Duggal, Pushpendra Singh, Preetika Sharma, Jasmeet Kaur, Lakshmi Gopalakrishnan, Navneet Gill, Garima Singh, Alka Ahuja, Vijay Kumar, Laura Weil, Rashmi Bagga
Background. Significant disruptions in the perinatal continuum of care occur postpartum in India, despite it being a critical time to optimize maternal health and wellbeing. Group-oriented mHealth approaches may help mitigate the impact of limited access to care and the lack of social support that characterize this period. Our team developed and pilot tested a provider-moderated group intervention to increase education, communication with providers, to refer participants to in-person care, and to connect them with a virtual social support group of other mothers with similarly aged infants through weekly calls and text chat...
December 22, 2023: Research Square
https://read.qxmd.com/read/37790487/user-acceptability-and-perceived-impact-of-a-mobile-interactive-education-and-support-group-intervention-to-improve-postnatal-health-care-in-northern-india-a-qualitative-study
#2
Valentina Cox, Preetika Sharma, Garima Singh Verma, Navneet Gill, Nadia G Diamond-Smith, Mona Duggal, Vijay Kumar, Rashmi Bagga, Jasmeet Kaur, Pushpendra Singh, Alison M El Ayadi
Background Postnatal care, crucial for preventing and assessing complications after birth, remains low in India. An interactive mHealth community-based postnatal intervention was implemented to promote healthy maternal behaviors through knowledge and social support in rural Northern India. However, there is limited information on how virtual health interventions in resource-constrained settings are perceived by the users and which elements influence their engagement and sustained participation. Objective We explored the user perceptions of acceptability and impact of a virtual interactive maternal and child health intervention pilot tested in Punjab State, India, including their perspectives on barriers and facilitators to engage with this intervention...
September 18, 2023: Research Square
https://read.qxmd.com/read/37703091/diagnosing-the-dermatologic-blues-systematic-review-of-the-rare-conundrum-psychogenic-purpura
#3
REVIEW
Praneet K Gill, Amy Zeglinski-Spinney
BACKGROUND: Psychogenic purpura is an idiopathic psychodermatologic condition of recurrent, painful purpura precipitated by psychological stress, predominantly affecting young females. Little consensus exists on the diagnostic guidelines for this rare condition, often resulting in costly, unnecessary, and stressful investigations as well as prolonged hospital admissions. OBJECTIVE: With this first up-to-date systematic review of 134 cases of psychogenic purpura in over a decade, we aim to thoroughly investigate the diagnostic strategy and treatment regimens used in the last decade...
September 13, 2023: JMIR dermatology
https://read.qxmd.com/read/37672109/cadmium-109-internal-kinetics-in-diamond-sturgeon-acipenser-gueldenstaedtii-are-strongly-influenced-by-salinity-exposure-pathway-and-history
#4
JOURNAL ARTICLE
Ross A Jeffree, Scott J Markich, Francois Oberhaensli, Jean-Louis Teyssie
Cadmium-109 whole-body and internal biokinetics were experimentally investigated in critically endangered diamond sturgeon Acipenser gueldenstaedtii after uptake from water or food, in fresh (FW) and brackish (BW; 9‰) salinities typical of the Caspian Sea. Whole-body rates of uptake of 109 Cd from water and subsequent depuration were quantified over 14 and 28 days, respectively. Uptake was greater in FW than BW by a factor of 2.4, but depuration rates were similar in both salinities. In contrast, for the dietary (chironomid) exposure pathway 109 Cd assimilation efficiencies (AEs) were higher in BW (13%) compared to FW (9...
September 6, 2023: Archives of Environmental Contamination and Toxicology
https://read.qxmd.com/read/37530426/peptidomimetic-oligomers-targeting-membrane-phosphatidylserine-exhibit-broad-antiviral-activity
#5
JOURNAL ARTICLE
Patrick M Tate, Vincent Mastrodomenico, Christina Cunha, Joshua McClure, Annelise E Barron, Gill Diamond, Bryan C Mounce, Kent Kirshenbaum
The development of durable new antiviral therapies is challenging, as viruses can evolve rapidly to establish resistance and attenuate therapeutic efficacy. New compounds that selectively target conserved viral features are attractive therapeutic candidates, particularly for combating newly emergent viral threats. The innate immune system features a sustained capability to combat pathogens through production of antimicrobial peptides (AMPs); however, these AMPs have shortcomings that can preclude clinical use...
August 2, 2023: ACS Infectious Diseases
https://read.qxmd.com/read/37407992/biobanking-and-consenting-to-research-a-qualitative-thematic-analysis-of-young-people-s-perspectives-in-the-north-east-of-england
#6
JOURNAL ARTICLE
Fabian J S van der Velden, Emma Lim, Lily Gills, Jasmin Broadey, Louise Hayes, Eve Roberts, Jack Courtney, Joanne Ball, Jethro Herberg, Rachel Galassini, Marieke Emonts
BACKGROUND: Biobanking biospecimens and consent are common practice in paediatric research. We need to explore children and young people's (CYP) knowledge and perspectives around the use of and consent to biobanking. This will ensure meaningful informed consent can be obtained and improve current consent procedures. METHODS: We designed a survey, in co-production with CYP, collecting demographic data, views on biobanking, and consent using three scenarios: 1) prospective consent, 2) deferred consent, and 3) reconsent and assent at age of capacity...
July 5, 2023: BMC Medical Ethics
https://read.qxmd.com/read/37275654/impact-of-transfused-citrate-on-pathophysiology-in-massive-transfusion
#7
REVIEW
Jacob B Schriner, J Michael Van Gent, M Adam Meledeo, Scott D Olson, Bryan A Cotton, Charles S Cox, Brijesh S Gill
UNLABELLED: This narrative review article seeks to highlight the effects of citrate on physiology during massive transfusion of the bleeding patient. DATA SOURCES: A limited library of curated articles was created using search terms including "citrate intoxication," "citrate massive transfusion," "citrate pharmacokinetics," "hypocalcemia of trauma," "citrate phosphate dextrose," and "hypocalcemia in massive transfusion." Review articles, as well as prospective and retrospective studies were selected based on their relevance for inclusion in this review...
June 2023: Critical care explorations
https://read.qxmd.com/read/36906294/addressing-sex-based-disparities-in-solid-organ-transplantation-in-the-united-states-a-conference-report
#8
Deirdre Sawinski, Jennifer C Lai, Sean Pinney, Alice L Gray, Annette M Jackson, Darren Stewart, Deborah Jo Levine, Jayme E Locke, James J Pomposelli, Matthew G Hartwig, Shelley A Hall, Darshana M Dadhania, Rebecca Cogswell, Richard V Perez, Jesse D Schold, Nicole A Turgeon, Jon Kobashigawa, Jasleen Kukreja, John C Magee, John Friedewald, John S Gill, Gabriel Loor, Julie K Heimbach, Elizabeth C Verna, Mary Norine Walsh, Norah Terrault, Guiliano Testa, Joshua M Diamond, Peter P Reese, Kimberly Brown, Susan Orloff, Maryjane A Farr, Kim M Olthoff, Mark Siegler, Nancy Ascher, Sandy Feng, Bruce Kaplan, Elizabeth Pomfret
Solid organ transplantation provides the best treatment for end-stage organ failure, but significant sex-based disparities in transplant access exist. On June 25, 2021, a virtual multidisciplinary conference was convened to address sex-based disparities in transplantation. Common themes contributing to sex-based disparities were noted across kidney, liver, heart, and lung transplantation, specifically the existence of barriers to referral and wait listing for women, the pitfalls of using serum creatinine, the issue of donor/recipient size mismatch, approaches to frailty and a higher prevalence of allosensitization among women...
March 2023: American Journal of Transplantation
https://read.qxmd.com/read/36248884/axial-spondyloarthritis-patients-have-altered-mucosal-iga-response-to-oral-and-fecal-microbiota
#9
JOURNAL ARTICLE
Tejpal Gill, Patrick Stauffer, Mark Asquith, Ted Laderas, Tammy M Martin, Sean Davin, Matthew Schleisman, Claire Ramirez, Kimberly Ogle, Ingrid Lindquist, Justine Nguyen, Stephen R Planck, Carley Shaut, Sarah Diamond, James T Rosenbaum, Lisa Karstens
Axial spondyloarthritis (axSpA) is an inflammatory arthritis involving the spine and the sacroiliac joint with extra-articular manifestations in the eye, gut, and skin. The intestinal microbiota has been implicated as a central environmental component in the pathogenesis of various types of spondyloarthritis including axSpA. Additionally, alterations in the oral microbiota have been shown in various rheumatological conditions, such as rheumatoid arthritis (RA). Therefore, the aim of this study was to investigate whether axSpA patients have an altered immunoglobulin A (IgA) response in the gut and oral microbial communities...
2022: Frontiers in Immunology
https://read.qxmd.com/read/36236884/optimal-design-of-the-annular-groove-phase-mask-central-region
#10
JOURNAL ARTICLE
Lorenzo König, Olivier Absil, Michaël Lobet, Christian Delacroix, Mikael Karlsson, Gilles Orban de Xivry, Jérôme Loicq
Vortex phase masks have been shown to be an efficient means to reduce the blinding stellar light in high-contrast imaging instruments. Once placed at the focal plane of the telescope, the helical phase ramp of a vortex phase mask diffracts the light of a bright on-axis source outside the re-imaged telescope pupil, while transmitting the light of a faint off-axis companion nearly unaffected. The Annular Groove Phase Mask (AGPM) is a broadband metasurface implementation of a vector vortex phase mask using the artificial birefringence of a circular subwavelength grating etched onto a diamond substrate...
July 18, 2022: Optics Express
https://read.qxmd.com/read/36018039/anti-persister-and-anti-biofilm-activity-of-self-assembled-antimicrobial-peptoid-ellipsoidal-micelles
#11
JOURNAL ARTICLE
Jennifer S Lin, Laurent A Bekale, Natalia Molchanova, Josefine Eilsø Nielsen, Megan Wright, Brian Bacacao, Gill Diamond, Håvard Jenssen, Peter L Santa Maria, Annelise E Barron
Although persister cells are the root cause of resistance development and relapse of chronic infections, more attention has been focused on developing antimicrobial agents against resistant bacterial strains than on developing anti-persister agents. Frustratingly, the global preclinical antibacterial pipeline does not include any anti-persister drug. Therefore, the central point of this work is to explore antimicrobial peptidomimetics called peptoids (sequence-specific oligo- N -substituted glycines) as a new class of anti-persister drugs...
September 9, 2022: ACS Infectious Diseases
https://read.qxmd.com/read/35903612/editorial-cellular-mechanisms-of-aging-and-longevity-in-oral-health-and-disease
#12
EDITORIAL
Christopher W Cutler, Gill Diamond
No abstract text is available yet for this article.
2022: Front Oral Health
https://read.qxmd.com/read/35748453/evaluation-of-fracture-resistance-of-reattached-fractured-tooth-fragment-stored-in-different-storage-media-an-in-vitro-study
#13
JOURNAL ARTICLE
Shivangi Trivedi, Abhishek Bansal, Navneet Kukreja, Aparna Trivedi, Swati Chhabra, Rikki Deswal, Parwan Gill, Archana Jain
AIM: To evaluate the fracture resistance of coronal fractured tooth fragments stored in five different storage media when reattached with nanohybrid flowable composite. MATERIALS AND METHODS: The crown portion of 50 extracted human permanent maxillary central incisors were divided into three equal parts (incisal third, middle third and cervical third) and then marked incisal third were cut with the diamond disk. These were divided into five equal groups according to the type of storage media used i...
February 1, 2022: Journal of Contemporary Dental Practice
https://read.qxmd.com/read/35717649/kannaphallus-leptosomus-n-sp-monogenea-heteraxinidae-cemocotylinae-parasitizing-scyris-indica-carangiformes-carangidae-from-malaysia
#14
JOURNAL ARTICLE
Masato Nitta, Yusuke Kondo, Susumu Ohtsuka, Ahmad Syazni Kamarudin, Norshida Ismail
A new monogenean species, Kannaphallus leptosomus n. sp., from the gills of the diamond trevally, Scyris indica Rüppell, caught off Terengganu, Peninsular Malaysia is described with molecular data. The new species differs from other species of the genus by the morphology of the largest clamp, the presence of a penis gun-associated needle, the unarmed genital atrium size, and the presence of two independent vaginal tubes. Previous records of Kannaphallus species were compiled, and four nominal species including one species incertae sedis (K...
June 19, 2022: Systematic Parasitology
https://read.qxmd.com/read/34782471/quantum-magnetic-imaging-of-iron-organelles-within-the-pigeon-cochlea
#15
JOURNAL ARTICLE
Robert W de Gille, Julia M McCoey, Liam T Hall, Jean-Philippe Tetienne, E Pascal Malkemper, David A Keays, Lloyd C L Hollenberg, David A Simpson
The ability of pigeons to sense geomagnetic fields has been conclusively established despite a notable lack of determination of the underlying biophysical mechanisms. Quasi-spherical iron organelles previously termed "cuticulosomes" in the cochlea of pigeons have potential relevance to magnetoreception due to their location and iron composition; however, data regarding the magnetic susceptibility of these structures are currently limited. Here quantum magnetic imaging techniques are applied to characterize the magnetic properties of individual iron cuticulosomes in situ...
November 23, 2021: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/34527214/examination-of-gene-expression-in-saliva-samples-from-covid-19-patients-to-study-the-host-defense-response-against-sars-cov-2-in-the-oral-cavity
#16
JOURNAL ARTICLE
Gill Diamond, Erika L Figgins, Tanya Robinson, Michal Senitko, George E Abraham, Haley B Williams, Meredith Sloan, Anna Owings, Hannah Laird, Yilianys Pride, Kenneth J Wilson, Mohammad Hasan, Adam Parker, Sarah C Glover
No abstract text is available yet for this article.
April 2021: Molecular Oral Microbiology
https://read.qxmd.com/read/34090062/determination-of-shedder-status-a-comparison-of-two-methods-involving-cell-counting-in-fingerprints-and-the-dna-analysis-of-handheld-tubes
#17
JOURNAL ARTICLE
Helen Johannessen, Peter Gill, Arne Roseth, Ane Elida Fonneløp
The shedder status of an individual may be important to consider in the context of DNA transfer, persistence and recovery and in Bayesian networks where a person's shedder status may have an impact on the outcome. In this study we compared two methods to determine shedder status: the handheld tube (HH) method and a fluorescent cell count (CC) method. A poor association was observed between the numbers of detected cells in a fingerprint using the CC method and the strength of the DNA result with the HH method...
May 28, 2021: Forensic Science International. Genetics
https://read.qxmd.com/read/34072631/antifungal-peptides
#18
EDITORIAL
Gill Diamond
Fungal infections represent an increasing public health crisis [...].
May 31, 2021: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/34047305/increased-ace2-levels-and-mortality-risk-of-patients-with-covid-19-on-proton-pump-inhibitor-therapy
#19
MULTICENTER STUDY
Julia J Liu, Meredith E Sloan, Anna H Owings, Erika Figgins, Josee Gauthier, Raad Gharaibeh, Tanya Robinson, Haley Williams, Campbell B Sindel, Fremel Backus, Krishna Ayyalasomayajula, Adam Parker, Michal Senitko, George E Abraham, Brian Claggett, Bruce H Horwitz, Christian Jobin, Robert M Adelman, Gill Diamond, Sarah C Glover
INTRODUCTION: Proton pump inhibitor (PPI) use was recently reported to be associated with increased severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and worse clinical outcomes. The underlying mechanism(s) for this association are unclear. METHODS: We performed a prospective study of hospitalized coronavirus disease 2019 (COVID-19) patients and COVID-negative controls to understand how PPI use may affect angiotensin-converting enzyme 2 (ACE2) expression and stool SARS-CoV-2 RNA...
August 1, 2021: American Journal of Gastroenterology
https://read.qxmd.com/read/33807248/potent-antiviral-activity-against-hsv-1-and-sars-cov-2-by-antimicrobial-peptoids
#20
JOURNAL ARTICLE
Gill Diamond, Natalia Molchanova, Claudine Herlan, John A Fortkort, Jennifer S Lin, Erika Figgins, Nathen Bopp, Lisa K Ryan, Donghoon Chung, Robert Scott Adcock, Michael Sherman, Annelise E Barron
Viral infections, such as those caused by Herpes Simplex Virus-1 (HSV-1) and SARS-CoV-2, affect millions of people each year. However, there are few antiviral drugs that can effectively treat these infections. The standard approach in the development of antiviral drugs involves the identification of a unique viral target, followed by the design of an agent that addresses that target. Antimicrobial peptides (AMPs) represent a novel source of potential antiviral drugs. AMPs have been shown to inactivate numerous different enveloped viruses through the disruption of their viral envelopes...
March 31, 2021: Pharmaceuticals
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