keyword
https://read.qxmd.com/read/36529928/association-between-periodontitis-and-blood-ocular-barrier-disruption
#1
JOURNAL ARTICLE
Minna Karesvuo, Sam Häyry, Petteri Karesvuo, Piotr Kanclerz, Raimo Tuuminen
PURPOSE: Periodontitis causes low-grade systemic inflammation e.g., through circulatory periodontal endotoxins, and it has been associated with cardiovascular morbidity and wet age-related macular degeneration. METHODS: To assess the association between clinical severity of periodontitis and aqueous flare levels in the eyes. Patients with periodontitis (N = 15) who underwent periodontal treatment by a specialized dentist between the years 2020 and 2021 at the Chin and Mouth Disease Unit, Kymenlaakso Central Hospital, Kotka, Finland were enrolled...
December 18, 2022: European Journal of Ophthalmology
https://read.qxmd.com/read/36243399/sap-deficiency-aggravates-periodontitis-possibly-via-c5a-c5ar-signaling-mediated-defective-macrophage-phagocytosis-of-porphyromonas-gingivalis
#2
JOURNAL ARTICLE
Liping Wang, Dongliang Liang, Yinyin Huang, Yunxin Chen, Xiaocong Yang, Zhijun Huang, Yiqin Jiang, Hanfu Su, Lijing Wang, Janak L Pathak, Linhu Ge
INTRODUCTION: Serum amyloid P component (SAP) regulates the innate immune system and microbial diseases. Periodontitis is an inflammatory oral disease developed by the host immune system's interaction with the dysbiotic oral microbiome, thereby SAP could play a role in periodontitis pathogenicity. OBJECTIVES: To investigate the role of SAP in oral microbiome modulation and peridontitis pathogenicity. METHODS: In this study, wildtype and SAP-knockout (KO) mice were used...
October 12, 2022: Journal of Advanced Research
https://read.qxmd.com/read/35946242/evaluation-of-serum-interleukin-33-and-soluble-suppression-of-tumorigenicity-2-sst2-receptors-in-patients-with-and-without-periodontal-disease
#3
JOURNAL ARTICLE
Himadri Singh, Abhinav Singh, Rohit Saluja
Context: : Interleukin-33 and its receptor soluble suppression of tumorigenicity 2. (: sST2) play an important role in inflammation and its role in periodontal disease is yet unclear. The role of both IL-33 and sST2 together in periodontal disease as biomarkers has never been studied. Aim: : To assess the levels of IL-33 and sST2 in serum samples of patients with periodontitis and healthy subjects. Methods: : A total of 71 subjects (30 healthy subjects and 41 patients with periodontal disease) were included in the cross-sectional study...
January 2022: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://read.qxmd.com/read/35764847/peridontitis-as-a-risk-factor-for-attention-deficit-hyperactivity-disorder-possible-neuro-inflammatory-mechanisms
#4
REVIEW
Samson K Wilson, Jaya Thomas
Periodontitis is a condition caused mostly by the creation of a biofilm by the bacterium P. gingivalis, which releases toxins and damages the tooth structure. Recent research studies have reported association between dental health and neuropsychiatric illnesses. Neuroinflammation triggered by the first systemic inflammation caused by the bacterium present in the oral cavities is a plausible explanation for such a relationship. Substantial amount of evidence supports the role of neuroinflammation and dysfunction of the dopaminergic system in the pathology of ADHD (Attention deficit hyperactivity disorders)...
June 28, 2022: Neurochemical Research
https://read.qxmd.com/read/34575643/clinical-evaluation-of-pathognomonic-salivary-protease-fingerprinting-for-oral-disease-diagnosis
#5
JOURNAL ARTICLE
Garrit Koller, Eva Schürholz, Thomas Ziebart, Andreas Neff, Roland Frankenberger, Jörg W Bartsch
Dental decay (Caries) and periodontal disease are globally prevalent diseases with significant clinical need for improved diagnosis. As mediators of dental disease-specific extracellular matrix degradation, proteases are promising analytes. We hypothesized that dysregulation of active proteases can be functionally linked to oral disease status and may be used for diagnosis. To address this, we examined a total of 52 patients with varying oral disease states, including healthy controls. Whole mouth saliva samples and caries biopsies were collected and subjected to analysis...
August 30, 2021: Journal of Personalized Medicine
https://read.qxmd.com/read/33999313/glucose-variability-and-periodontal-disease-in-type-1-diabetes-a-cross-sectional-study-the-parodontopatia-e-diabete-parodia-project
#6
JOURNAL ARTICLE
Ilaria Dicembrini, Luigi Barbato, Lapo Serni, Mariasmeralda Caliri, Laura Pala, Francesco Cairo, Edoardo Mannucci
AIMS: Periodontal disease (PD) is a chronic inflammation of periodontal tissue associated with infection from specific anaerobic pathogens contained in dental plaque. Both type 1 and type 2 diabetes are associated with an increased prevalence of PDs. A two-way relationship between diabetes and periodontitis has been proposed, with diabetes increasing the risk for periodontitis, and periodontal inflammation negatively affecting glycaemic control. To date, the relationship between PD and glucose variability in type 1 diabetes has not been evaluated...
October 2021: Acta Diabetologica
https://read.qxmd.com/read/32718217/positive-effect-of-curcumin-on-experimental-peridontitis-via-suppression-of-il-1-beta-and-il-6-expression-level
#7
JOURNAL ARTICLE
Zuhal Yetkin Ay, Burcu Bakır, Şerife Buket Bozkurt, Seyit Ali Kayis, Sema Sezgin Hakki
<b/> This study examined the effect of curcumin on T-helper (Th17) and T-regulatory (Treg) cells regarding the mRNA of cytokines/mediators in the gingiva. Thirty-five male albino Wistar rats were divided into four groups: Group 1: periodontitis (n = 9); Group 2: periodontitis with curcumin treatment (n = 8); Group 3: periodontally healthy with curcumin treatment (n = 10); and Group 4: periodontally healthy (n = 8). Curcumin was administered via oral gavage (30 mg/kg/day) for a total of 15 days...
July 2022: International Journal for Vitamin and Nutrition Research. Journal International de Vitaminologie et de Nutrition
https://read.qxmd.com/read/32071466/-associations-of-impaired-glucose-metabolism-with-chronic-peridontitis-in-pre-diabetes-patients
#8
JOURNAL ARTICLE
Y Zhang, C Liu, B Chen, F Chen, J Y Duan, M J Zhang, J Jiao
OBJECTIVE: To investigate the associations of impaired glucose metabolism and insulin resistance with chronic periodontitis in pre-diabetes patients. METHODS: A cross-sectional analysis was conducted and we included a total of 171 pre-diabetes patients aged 30-65 years, free of diabetes. pre-diabetes was defined as impaired fasting glucose (IFG) [fasting glucose (FG): 6.1-7.0 mmol/L] and/or impaired glucose tolerance (IGT) [oral glucose tolerance test (OGTT): 7...
February 18, 2020: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://read.qxmd.com/read/31913739/minocycline-loaded-plga-electrospun-membrane-prevents-alveolar-bone-loss-in-experimental-peridontitis
#9
JOURNAL ARTICLE
Yihui Ma, Jinlin Song, Huthayfa N S Almassri, Dan Zhang, Ting Zhang, Yuting Cheng, Xiaohong Wu
Minocycline (MINO) is a tetracycline antibiotic effective against most of the bacteria microorganisms related to periodontal disease. Additionally, MINO promotes bone in vitro and in vivo . The objective of the present study was to establish the protocol for the preparation of MINO-loaded poly (lactic- co -glycolic acid) (MINO-PLGA) electrospun membranes and to evaluate their effect on osteogenesis in vitro and in a rat model of periodontitis. The characterization of MINO-PLGA electrospun membranes was assessed by scanning electron microscopy, laser scanning confocal microscopy, and contact angle measurement...
December 2020: Drug Delivery
https://read.qxmd.com/read/31132200/in-the-dental-implant-era-why-do-we-still-bother-saving-teeth
#10
REVIEW
Danielle Clark, Liran Levin
Teeth are vital sensory organs that contribute to our daily activities of living. Unfortunately, teeth can be lost for several reasons including trauma, caries, and periodontal disease. Although dental trauma injuries and caries are more frequently encountered in a younger population, tooth loss because of periodontal disease occurs in the older population. In the dental implant era, the trend sometimes seems to be to extract compromised teeth and replace them with dental implants. However, the long-term prognosis of teeth might not be comparable with the prognosis of dental implants...
December 2019: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://read.qxmd.com/read/28839412/correlation-of-abo-blood-group-phenotype-and-rhesus-factor-with-periodontal-disease-an-observational-study
#11
JOURNAL ARTICLE
Anju Gautam, Neelam Mittal, T B Singh, Ruchi Srivastava, Pushpendra Kumar Verma
BACKGROUND: The knowledge of the ABO blood group phenotype of the patients and their correlation with the periodontal disease maybe important in the development of early treatment strategies, and it would be helpful to target non-responding areas to periodontal therapy of the susceptible individuals. AIMS: The present study was conducted to determine whether there was any correlation between periodontal diseases and ABO blood groups and Rh factor. MATERIAL AND METHOD: This study was carried out on 537 subjects attending Faculty of Dental Sciences OPD in BHU...
April 2017: Contemporary Clinical Dentistry
https://read.qxmd.com/read/28740273/mandibular-osteonecrosis-due-to-the-pulpal-periodontal-syndrome-a-case-report-and-review-of-the-literature
#12
JOURNAL ARTICLE
Dragana Gabrić, Sven Seiwerth, Anja Baraba, Vanja Vučićević, Boras
OBJECTIVE: Ishemic bone disease has multifactorial etiologies. Cronic dental infections should be eliminated to prevent osteonecrosis of the jaw. CASE REPORT: We report an unusual case of osteonecrosis due to the pulpal-peridontal syndrome and subsequent pulp necrosis. A case of 38 year old woman who presented with exposed bone, 8 mm in diameter, in the lingual area of the right lower third molar. The patient was otherwise healthy and was not taking any medications...
March 2017: Acta Stomatologica Croatica
https://read.qxmd.com/read/28358286/association-of-cytokines-polymorphisms-with-chronic-peridontitis-and-rheumatoid-arthritis-in-a-mexican-population
#13
JOURNAL ARTICLE
Rubén Abraham Domínguez-Pérez, Juan Pablo Loyola-Rodriguez, Carlos Abud-Mendoza, Angel Gabriel Alpuche-Solis, José Luis Ayala-Herrera, Rita Elizabeth Martínez-Martínez
OBJECTIVE: Historically, it has been shown that rheumatoid arthritis (RA) and periodontitis (PE) share pathophysiological similarities and possibly a genetic background. In order to elucidate the genetic background between both diseases, we evaluated the distributions of five SNPs genotypes and all the possible haplotypes composed in subjects with isolated RA, PE, combined diseases and healthy controls. MATERIALS AND METHODS: The study population consisted of 280 Mexican subjects...
May 2017: Acta Odontologica Scandinavica
https://read.qxmd.com/read/25443979/interrelationship-between-diabetes-and-periodontitis-role-of-hyperlipidemia
#14
REVIEW
Xiaodong Zhou, Wenyi Zhang, Xiaoli Liu, Wu Zhang, Yiming Li
Diabetes mellitus and periodontitis are both common, chronic diseases. It is generally accepted that the inter-relationship between diabetes mellitus and periodontitis is a two-way relationship, i.e. the presence of one condition tends to increases the risk and severity of the other, and vice versa. Mechanisms for this two-way relationship are largely unknown. Hyperlipidemia is a group of disorders characterized by an excess of lipids in the bloodstream. Hyperlipidemia increases the risk of diabetes and peridontitis...
April 2015: Archives of Oral Biology
https://read.qxmd.com/read/25279394/association-of-periodontal-pathogenesis-and-cardiovascular-diseases-a-literature-review
#15
REVIEW
Umair Ahmed, Farzeen Tanwir
PURPOSE: To present a short review of recent literature available on the association of periodontal and cardiovascular diseases (CVD) and the role of peridontal disease as a risk factor to exacerbate CVD. MATERIALS AND METHODS: A thorough search of articles was carried out on the databases PUBMED and MEDLINE on the association of periodontal and cardiovascular diseases (CVD). The selected literature included review articles, observational and case-control studies as well as randomised control trials...
2015: Oral Health & Preventive Dentistry
https://read.qxmd.com/read/24619787/periodontal-disease-as-a-potential-risk-factor-for-low-birth-weight-and-reduced-maternal-haemomglobin-levels
#16
JOURNAL ARTICLE
Shaila V Kothiwale, Babasaheb R Desai, Veerappa A Kothiwale, Megha Gandhid, Savita Konin
PURPOSE: To investigate the association between maternal periodontal disease and its effect on haemoglobin levels and low birth weight infants. MATERIALS AND METHODS: This observational study included 770 mothers. Data regarding the periodontal status, pregnancy outcome variables, haemoglobin levels (Hb%) and other factors that may contribute to adverse pregnancy outcomes were collected. The data were analysed using the chi-square test and univariate logistic regression analysis...
2014: Oral Health & Preventive Dentistry
https://read.qxmd.com/read/24558523/utility-of-periodontal-exploration-in-patients-with-fibromyalgia
#17
JOURNAL ARTICLE
Rocío Santos-García, Benito Sánchez-Domínguez, Mario D Cordero, José V Rios-Santos, María R Jaramillo-Santos, Mariano H Climent, Pedro Bullon
OBJECTIVE: [corrected] Fibromyalgia (FM) is a chronic pain syndrome with unknown etiology, which affects predominantly women. Mitochondrial alteration could have a role in the pathophysilogical mechanisms of inflammatory conditions as FM and periodontitis. The aim of the present study was assay the relationship between both diseases and mitochondrial dysfunction. PATIENT AND METHODS: We study the presence of periodontitis in twelve patients diagnosed of FM and mitochondrial dysfunction described...
February 2012: Journal of Clinical and Experimental Dentistry
https://read.qxmd.com/read/23235134/case-report-cystic-hygroma
#18
JOURNAL ARTICLE
S Barry, J Allotey, A M Brundler, M S Duggal
BACKGROUND: Cystic hygroma (CH) is a congenital malformation of the lymphatic system. It most commonly presents in the neck, and aetiological factors include environmental and genetic factors. CASE REPORT: A 13-year-old female presented with spontaneous dental pain affecting the maxillary left first and second permanent molar teeth. Medical history revealed a history of left sided cervico-facial-thoracic CH. She was diagnosed with periapical peridontitis and required extraction of both teeth...
December 2012: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://read.qxmd.com/read/22556832/role-of-triphala-in-the-management-of-peridontal-disease
#19
JOURNAL ARTICLE
D K Maurya, N Mittal, K R Sharma, G Nath
Ayurvedic literature contains a wealth of information on the diagnosis and treatment of periodontal diseases. This article discusses the use of triphala in the treatment of such diseases.
October 1997: Ancient Science of Life
https://read.qxmd.com/read/21931203/detection-of-il-4-il-6-and-il-12-serum-levels-in-generalized-aggressive-periodontitis
#20
JOURNAL ARTICLE
Maryam Robati, Ardeshir Ranjbari, Mehri Ghafourian Boroujerdnia, Zahra Chinipardaz
BACKGROUND: Periodontitis is a multifactorial chronic inflammatory disease characterized by destruction of tooth-supporting tissues. Environmental and genetic factors as well as the immune system participate in this process. Recent studies have attempted to elucidate the role of cytokine networks involved in periodontal diseases. OBJECTIVE: To assess and compare the levels of IL-4, IL-6 and IL-12 in serum samples of patients with generalized aggressive periodontitis (GAgP) and control individuals...
September 2011: Iranian Journal of Immunology: IJI
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