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peridontal disease

Xiaodong Zhou, Wenyi Zhang, Xiaoli Liu, Wu Zhang, Yiming Li
Diabetes mellitus and periodontitis are both common, chronic diseases. It is generally accepted that the inter-relationship between diabetes mellitus and periodontitis is a two-way relationship, i.e. the presence of one condition tends to increases the risk and severity of the other, and vice versa. Mechanisms for this two-way relationship are largely unknown. Hyperlipidemia is a group of disorders characterized by an excess of lipids in the bloodstream. Hyperlipidemia increases the risk of diabetes and peridontitis...
April 2015: Archives of Oral Biology
Umair Ahmed, Farzeen Tanwir
PURPOSE: To present a short review of recent literature available on the association of periodontal and cardiovascular diseases (CVD) and the role of peridontal disease as a risk factor to exacerbate CVD. MATERIALS AND METHODS: A thorough search of articles was carried out on the databases PUBMED and MEDLINE on the association of periodontal and cardiovascular diseases (CVD). The selected literature included review articles, observational and case-control studies as well as randomised control trials...
2015: Oral Health & Preventive Dentistry
Shaila V Kothiwale, Babasaheb R Desai, Veerappa A Kothiwale, Megha Gandhid, Savita Konin
PURPOSE: To investigate the association between maternal periodontal disease and its effect on haemoglobin levels and low birth weight infants. MATERIALS AND METHODS: This observational study included 770 mothers. Data regarding the periodontal status, pregnancy outcome variables, haemoglobin levels (Hb%) and other factors that may contribute to adverse pregnancy outcomes were collected. The data were analysed using the chi-square test and univariate logistic regression analysis...
2014: Oral Health & Preventive Dentistry
Rocío Santos-García, Benito Sánchez-Domínguez, Mario D Cordero, José V Rios-Santos, María R Jaramillo-Santos, Mariano H Climent, Pedro Bullon
OBJECTIVE: [corrected] Fibromyalgia (FM) is a chronic pain syndrome with unknown etiology, which affects predominantly women. Mitochondrial alteration could have a role in the pathophysilogical mechanisms of inflammatory conditions as FM and periodontitis. The aim of the present study was assay the relationship between both diseases and mitochondrial dysfunction. PATIENT AND METHODS: We study the presence of periodontitis in twelve patients diagnosed of FM and mitochondrial dysfunction described...
February 2012: Journal of Clinical and Experimental Dentistry
S Barry, J Allotey, A M Brundler, M S Duggal
BACKGROUND: Cystic hygroma (CH) is a congenital malformation of the lymphatic system. It most commonly presents in the neck, and aetiological factors include environmental and genetic factors. CASE REPORT: A 13-year-old female presented with spontaneous dental pain affecting the maxillary left first and second permanent molar teeth. Medical history revealed a history of left sided cervico-facial-thoracic CH. She was diagnosed with periapical peridontitis and required extraction of both teeth...
December 2012: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
D K Maurya, N Mittal, K R Sharma, G Nath
Ayurvedic literature contains a wealth of information on the diagnosis and treatment of periodontal diseases. This article discusses the use of triphala in the treatment of such diseases.
October 1997: Ancient Science of Life
Maryam Robati, Ardeshir Ranjbari, Mehri Ghafourian Boroujerdnia, Zahra Chinipardaz
BACKGROUND: Periodontitis is a multifactorial chronic inflammatory disease characterized by destruction of tooth-supporting tissues. Environmental and genetic factors as well as the immune system participate in this process. Recent studies have attempted to elucidate the role of cytokine networks involved in periodontal diseases. OBJECTIVE: To assess and compare the levels of IL-4, IL-6 and IL-12 in serum samples of patients with generalized aggressive periodontitis (GAgP) and control individuals...
September 2011: Iranian Journal of Immunology: IJI
Jing Liu, Liang-jun Zhong, Fang-chuan Shi, Lei Zhang, Qiong Zhang, Da-lei Sun
OBJECTIVE: To examine the expression of tumor necrosis factor in placenta of pregnant rats with chronic periodontitis. METHODS: Twenty Wistar female rats were randomly divided into two groups, control (n = 8) and experimental group (n = 12). The periodontitis model was established in the experimental group. The females and males in the two groups got together four weeks later. Nineteen days after pregnancy all rats were executed and placenta collected. The delivery time and neonatal birth weight were recorded and the pathological changes of periodontal tissue observed...
May 2011: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
Predrag Sikiric, Sven Seiwerth, Rudolf Rucman, Branko Turkovic, Dinko Stancic Rokotov, Luka Brcic, Marko Sever, Robert Klicek, Bozo Radic, Domagoj Drmic, Spomenko Ilic, Danijela Kolenc, Hrvoje Vrcic, Bozidar Sebecic
Stable gastric pentadecapeptide BPC 157 is an anti-ulcer peptidergic agent, safe in inflammatory bowel disease clinical trials (GEPPPGKPADDAGLV, M.W. 1419, PL 14736) and wound healing, stable in human gastric juice and has no reported toxicity. We focused on BPC 157 as a therapy in peridontitis, esophagus, stomach, duodenum, intestine, liver and pancreas lesions. Particularly, it has a prominent effect on alcohol-lesions (i.e., acute, chronic) and NSAIDs-lesions (interestingly, BPC 157 both prevents and reverses adjuvant arthritis)...
2011: Current Pharmaceutical Design
Núria Cerdà-Costa, Tibisay Guevara, Abdulkarim Y Karim, Miroslaw Ksiazek, Ky-Anh Nguyen, Joan L Arolas, Jan Potempa, F Xavier Gomis-Rüth
Metallopeptidases (MPs) are among virulence factors secreted by pathogenic bacteria at the site of infection. One such pathogen is Tannerella forsythia, a member of the microbial consortium that causes peridontitis, arguably the most prevalent infective chronic inflammatory disease known to mankind. The only reported MP secreted by T. forsythia is karilysin, a 52 kDa multidomain protein comprising a central 18 kDa catalytic domain (CD), termed Kly18, flanked by domains unrelated to any known protein. We analysed the 3D structure of Kly18 in the absence and presence of Mg(2+) or Ca(2+) , which are required for function and stability, and found that it evidences most of the structural features characteristic of the CDs of mammalian matrix metalloproteinases (MMPs)...
January 2011: Molecular Microbiology
Monica Wahlström, Gun-Britt Sagulin, Leif E Jansson
AIMS/BACKGROUND: The aims of the present study were to evaluate (1) the success rate of unilateral maxillary fixed dental prosthesis (FDPs) on implants in patients at a periodontal clinic referred for periodontal treatment, (2) the prevalence of varying mechanical and biological complications and (3) effects of potential risk factors on the success rate. MATERIAL AND METHODS: Fifty consecutive patients were invited to participate in a follow-up. The patients had received FDPs on implants between November 2000 and December 2003 after treatment to achieve optimal peridontal health, and the FDPs had been in function for at least 3 years...
November 2010: Clinical Oral Implants Research
Heng-biao Pan, Hui Chen, Na Zhou, Dan Jin, Jing Zhang, Chun-mei Peng
OBJECTIVE: To evaluate the relationship between periodontitis and the traditional risk factors of coronary heart disease (CHD), as well as the role in the mechanisms responsible for high-sensitivity C-reactive protein (hsCRP) in the relationship of peridontitis and CHD. METHODS: A periodontal examination was conducted on a total of 356 subjects, and community periodontal index of treatment needs (CPITN) was obtained from each subject. Periodontal status was categorized into TN < or =2, TN=3, TN=4 three groups according to the CPITN indexes...
August 2010: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
Sasa Cakić
Gingival crevicular fluid (GCF) can be found in the physiologic space (gingival sulcus), as well as in the pathological space (gingival pocket or periodontal pocket) between the gums and teeth. In the first case it is a transudate, in the second an exudate. The constituents of GCF originate from serum, gingival tissues, and from both bacterial and host response cells present in the aforementioned spaces and the surrounding tissues. The collection and analysis of GCF are the noninvasive methods for the evaluation of host response in periodontal disease...
May 2009: Srpski Arhiv za Celokupno Lekarstvo
Casey Hein
Evidence to support a bidirectional relationship between diabetes and periodontal disease has been emerging for more than 15 years. In 1993, Löe proposed that severe peridontitis was the sixth complication of diabetes; in 1996, Taylor and colleagues reported other compelling findings that severe periodontitis at baseline is associated with worsening glycemic control over time in a population-based study of Pima Indians with diabetes who were noninsulin dependent.
November 2008: Compendium of Continuing Education in Dentistry
Maria Chomyszyn-Gajewska, Dagmara Darczuk, Dagmara Gałecka-Wanatowicz, Agnieszka Cabała
On the basis of available literature, presented is the influence of smoking on incidence and progression of peridontal disease. During the process of smoking; more than 400 destructive substances along with nicotine are excreted. Their effects on peridontal tissue present as direct and indirect symptoms (due to disfunction of the immunological reactions) which permit for better conditions for pathological bacterial invasion and increased secretion of proinflammatory factors.
2008: Przegla̧d Lekarski
Mingyu Li, Zhuting Xu
In the course of a search for chemotherapeutic agents inhibiting suspected peridontitis bacteria, extracted and purified substances from lotus leaf were identified by antimicrobial activity tests with use of the broth micro-dilution methods on 96-microwell plate. The antimicrobial activity of extracts was tested against five microorganisms, namely: Actinobacillus actinomycetemcomitans Y4, Actinomyces viscosus 19246, Porphyromonas gingivalis 33277, Fusobacterium nucleatum 25586, and Actinomyces naeslundii wvl 45...
May 2008: Archives of Pharmacal Research
M G Dzgoeva
The state of peridontal microhemodynamics was investigated in 80 patients with an initial arterial hypotension (IAH) and 70 patients with an arterial hypertension (AH) of different age-groups (6, 15, 20-24, 40-45 years) according to the laser dopplerography method. A decrease of a bloodflow intensity in all agt-groups with IAH and in senior group with AH was estimated. Impairments of the regional hemodynamics were accompanied by the high rate of stomatological morbidity.
2007: Stomatologii︠a︡
Ming-Yu Li, Zhu-Ting Xu
OBJECTIVES: To search for a substance in lotus leaf that could efficiently be used in toothpaste for preventing periodontal disease. METHODS: Dried lotus leaves were hydrated and fractionated using 40% butanol and 40% ethanol extraction. The extracts and the residue were evaluated by antimicrobial sensitivity tests of broth micro-dilution methods on 96-microwell plates for inhibition of five species of oral bacteria: Actinobacillus actinomycetemcomitans Y4, Actinomyces viscosus 19246, Porphyromonas gingivalis 33277, Fusobacterium nucleatum 25586, and Actinomyces naeslundii wvl 45...
October 2007: International Dental Journal
Kjell Haram, Knut Gjelland
BACKGROUND: Intrauterine growth : restriction (IUGR) occurs in 3-10% of all pregnancies : The condition has different adverse effects on the foetus, during childhood and even in adult life. MATERIAL AND METHODS: Literature was retrieved from the Pub Med and Cochrane databases. RESULTS AND INTERPRETATION: The most common limit for IUGR and severe growth restriction is a neonatal weight < 10th percentile. Placental failure, infections or foetal anomalies may cause IUGR before the 32 nd gestational week (early IUGR)...
October 18, 2007: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
Esther Hullah, Yaroslava Turok, Maud Nauta, Wai Yoong
AIMS: The aim of this study was to describe self-reported oral health, oral hygiene habits, frequency of visits to a dentist and factors associated with dental attendance among pregnant women at a North London Hospital, the majority of whom are immigrants. BACKGROUND: Peridontal disease is associated with an increased risk of adverse pregnancy outcomes. The aim of this study is to describe self-reported oral health, oral hygiene habits, frequency of visits to a dentist and factors associated with dental attendance among pregnant women at a North London Hospital, the majority of whom are immigrants...
May 2008: Archives of Gynecology and Obstetrics
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