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https://www.readbyqxmd.com/read/29471581/association-of-quantitative-and-topographic-assessment-of-heberden-s-nodes-with-knee-osteoarthritis-data-from-osteoarthritis-initiative
#1
Neil Kumar, Nima Hafezi-Nejad, Ali Guermazi, Arya Haj-Mirzaian, Ida K Haugen, Frank W Roemer, Shadpour Demehri
OBJECTIVE: To determine whether the presence, number, and topography (digit location and symmetry) of Heberden's nodes (HNs) are associated with radiographic knee osteoarthritis (OA) incidence and progression. METHODS: 8023 knees from the Osteoarthritis Initiative (OAI) were analyzed (8-years follow-up). Cox regression was performed on HN presence, total number, location, and symmetry (using two symmetry index models) obtained at baseline physical-examination as well as self-report of HN presence for evaluation of association with radiographic knee OA incidence (development of Kellgren-Lawrence grade≥2) and progression (worsening medial joint space narrowing score≥1)...
February 22, 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29471518/differences-between-supportive-music-and-imagery-and-music-listening-during-outpatient-chemotherapy-and-potential-moderators-of-treatment-effects
#2
Debra S Burns, Anthony N Meadows, Sandra Althouse, Susan M Perkins, Larry D Cripe
Background: Supportive music and imagery and music listening interventions have been effective in decreasing distress and improving mood in cancer patients receiving chemotherapy, but it is unclear whether the two interventions differ in their treatment benefits. Furthermore, previous studies have not examined moderators to determine which subgroup(s) of patients may benefit most from each intervention. Objective: To examine the effects of supportive music and imagery compared with preferred music listening on responsiveness to music therapy, distress, anxiety and depression, and benefit finding...
February 8, 2018: Journal of Music Therapy
https://www.readbyqxmd.com/read/29471516/optical-spectral-transmission-to-assess-inflammation-in-hand-and-wrist-joints-of-rheumatoid-arthritis-patients
#3
Nick J Besselink, Patricia van der Meijde, Wouter H J Rensen, Peter B L Meijer, Anne C A Marijnissen, Jacob M van Laar, Floris P J G Lafeber, Johannes W G Jacobs
Objective: To develop an optical spectral transmission (OST) model to measure joint inflammation, and thus disease activity, as well as to evaluate (patho-)physiological findings that could lead to misclassification of inflammation. Methods: Forty-six RA patients were included in this cross-sectional study, where US scores, duplicate OST measurements and 28-joint DAS (DAS28) were acquired. With US as a reference standard, the diagnostic performance of OST in detecting inflammation at the joint level was evaluated using receiver operating characteristic (ROC) curve analyses...
February 19, 2018: Rheumatology
https://www.readbyqxmd.com/read/29471513/the-genetic-correlation-between-scapula-shape-and-shoulder-lesions-in-sows
#4
Ø Nordbø, L E Gangsei, T Aasmundstad, E Grindflek, J Kongsro
Shoulder lesions and body condition of sows at weaning have both environmental and genetic causes. The traits can be scored at farm-level, and following recording, the traits can be included in the breeding goal and directional selection can be applied. However, to further increase the genetic progress of these traits, it is advantageous to develop indicator traits on the selection candidates (test boars or gilts, not yet exhibiting the phenotype themselves). It has previously been suggested that the scapula morphology and the spine of scapula might be a key factor for the sow to develop shoulder lesions...
February 19, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29471457/improving-anatomic-pathology-in-sub-saharan-africa-to-support-cancer-care
#5
Michael L Wilson, Stephanie Ayers, Daniel Berney, Alexia Eslan, Jeannette Guarner, Susan Lester, Ricard Masia, Zahir Moloo, Angela Mutuku, Drucilla Roberts, Jennifer Stall, Shahin Sayed
Objectives: Cancer care requires both accurate pathologic diagnosis as well as pathologic cancer staging. We evaluated three approaches to training pathologists in sub-Saharan Africa to perform pathologic cancer staging of breast, cervix, prostate, and colorectal cancers. Methods: One of three training methods was used at each workshop: didactic, case-based testing (CBT), or a blended approach. The project involved 52 participants from 16 pathology departments in 11 countries in East, Central, and Southern Africa...
February 19, 2018: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29471393/the-severe-impairment-profile-a-conceptual-shift
#6
Jordan S Robinson, Robert L Collins, Brian I Miller, Vitor H Pacheco, Nicholas M Wisdom
Objective: The current study sought to evaluate and replicate the severe impairment profile (SIP) of the Word Memory Test (WMT) in patients referred for dementia evaluations. Method: The sample consisted of 125 patients referred for a neuropsychological evaluation at a large Veterans Affairs Medical Center. Patients were assigned a Clinical Dementia Rating (CDR) by blind raters, and were classified according to their performance on performance validity testing. Subsequent chart reviews were conducted to help in more accurately determining the presence of severe memory impairment likely due to an underlying dementing process versus poor effort/task engagement...
March 1, 2018: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/29471206/state-trait-anxiety-levels-during-pregnancy-and-foetal-parameters-following-intervention-with-music-therapy
#7
J Garcia-Gonzalez, M I Ventura-Miranda, M Requena-Mullor, T Parron-Carreño, R Alarcon-Rodriguez
BACKGROUND: Research indicates that anxiety during pregnancy may be a risk factor for the development of alterations in the mental health of the pregnant woman and of obstetric complications. OBJECTIVE: to investigate the effect of music therapy on maternal anxiety, before and after a non-stress test (NST), and the effect of maternal anxiety on the birthing process and birth size. METHODS: 409 nulliparous women coming for routine prenatal care were randomized in the third trimester to receive either music therapy (n = 204) or no music therapy (n = 205) during an NST...
February 13, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29470713/health-related-quality-of-life-in-patients-undergoing-cervico-thoracic-osteotomies-for-fixed-cervico-thoracic-kyphosis-in-patients-with-ankylosing-spondylitis
#8
Silviu Sabou, Hossein Mehdian, Dritan Pasku, Luca Boriani, Nasir A Quraishi
PURPOSE: Ankylosing spondylitis (AS) can result in severe cervico-thoracic kyphotic deformity (CTKD). Few studies have addressed the relationship between cervico-thoracic osteotomies in AS and health-related quality of life scores. The aim of this study is to evaluate the impact of cervico-thoracic osteotomy (CTO) on improving quality of life for patients with fixed CTKD. METHODS: A database of all patients who underwent a CTO for CTKD in patients with AS was created...
February 22, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29470616/automated-spect-analysis-compared-with-expert-visual-scoring-for-the-detection-of-ffr-defined-coronary-artery-disease
#9
R S Driessen, P G Raijmakers, I Danad, W J Stuijfzand, S P Schumacher, J A Leipsic, J K Min, J Knuuti, A A Lammertsma, A C van Rossum, N van Royen, S R Underwood, P Knaapen
PURPOSE: Traditionally, interpretation of myocardial perfusion imaging (MPI) is based on visual assessment. Computer-based automated analysis might be a simple alternative obviating the need for extensive reading experience. Therefore, the aim of the present study was to compare the diagnostic performance of automated analysis with that of expert visual reading for the detection of obstructive coronary artery disease (CAD). METHODS: 206 Patients (64% men, age 58...
February 22, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29470544/validation-of-the-what-matters-index-a-brief-patient-reported-index-that-guides-care-for-chronic-conditions-and-can-substitute-for-computer-generated-risk-models
#10
John H Wasson, Lynn Ho, Laura Soloway, L Gordon Moore
INTRODUCTION: Current health care delivery relies on complex, computer-generated risk models constructed from insurance claims and medical record data. However, these models produce inaccurate predictions of risk levels for individual patients, do not explicitly guide care, and undermine health management investments in many patients at lesser risk. Therefore, this study prospectively validates a concise patient-reported risk assessment that addresses these inadequacies of computer-generated risk models...
2018: PloS One
https://www.readbyqxmd.com/read/29470385/an-activity-recognition-framework-deploying-the-random-forest-classifier-and-a-single-optical-heart-rate-monitoring-and-triaxial-accelerometerwrist-band
#11
Saeed Mehrang, Julia Pietilä, Ilkka Korhonen
Wrist-worn sensors have better compliance for activity monitoring compared to hip, waist, ankle or chest positions. However, wrist-worn activity monitoring is challenging due to the wide degree of freedom for the hand movements, as well as similarity of hand movements in different activities such as varying intensities of cycling. To strengthen the ability of wrist-worn sensors in detecting human activities more accurately, motion signals can be complemented by physiological signals such as optical heart rate (HR) based on photoplethysmography...
February 22, 2018: Sensors
https://www.readbyqxmd.com/read/29470352/intraoperative-management-of-liver-transplant-patients-without-the-routine-use-of-renal-replacement-therapy
#12
Dieter Adelmann, Andrea Olmos, Linda L Liu, John R Feiner, Garrett R Roll, Lyle Burdine, Mehdi Tavakol, Shareef Syed, Babak J Orandi, Claus U Niemann
BACKGROUND: Renal failure is common among patients undergoing liver transplantation. Liver allocation based on the MELD score has increased the number of recipients who require perioperative RRT. Although renal replacement therapy (RRT) can be continued intraoperatively, the risks and benefits of intraoperative RRT are not well defined. The aim of this study is to report the intraoperative management of patients with pretransplant renal failure at a transplant center with extremely infrequent utilization of intraoperative RRT...
February 20, 2018: Transplantation
https://www.readbyqxmd.com/read/29470257/dynamic-patient-specific-three-dimensional-simulation-of-mitral-repair-can-we-practice-mitral-repair-preoperatively
#13
Olivia K Ginty, John M Moore, Yuanwei Xu, Wenyao Xia, Satoru Fujii, Daniel Bainbridge, Terry M Peters, Bob B Kiaii, Michael W A Chu
OBJECTIVE: Planned mitral repair strategies are generally established from preoperative echocardiography; however, specific details of the repair are often determined intraoperatively. We propose that three-dimensional printed, patient-specific, dynamic mitral valve models may help surgeons plan and trial all the details of a specific patient's mitral repair preoperatively. METHODS: Using preoperative echocardiography, segmentation, modeling software, and three-dimensional printing, we created dynamic, high-fidelity, patient-specific mitral valve models including the subvalvular apparatus...
February 22, 2018: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29470234/incidence-of-neuraxial-abnormalities-is-approximately-8-among-patients-with-adolescent-idiopathic-scoliosis-a-meta-analysis
#14
Michael Faloon, Nikhil Sahai, Todd P Pierce, Conor J Dunn, Kumar Sinha, Ki Soo Hwang, Arash Emami
BACKGROUND: Several studies have sought to address the role of routine preoperative MRI in patients with adolescent idiopathic scoliosis (AIS) undergoing deformity correction. Despite similar results regarding the prevalence of neuraxial anomalies detected on MRI, published conclusions conflict and give opposing recommendations. Lack of consensus has led to important variations in use of MRI before spinal surgery for patients with AIS. QUESTIONS/PURPOSES: This systematic review and meta-analysis of studies about patients with AIS evaluated (1) the overall proportion of neuraxial abnormalities; (2) the patient factors and curve characteristics that may be associated with abnormalities; and (3) the proportion of patients who underwent neurosurgical intervention before scoliosis surgery and the kinds of neuraxial lesions that were identified...
February 21, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29470004/accuracy-and-utility-of-estimating-lean-body-mass-and-nutritional-status-in-patients-with-chronic-kidney-disease-on-long-term-hemodialysis-using-anthropometric-skinfold-thickness-measurements
#15
Khai Gene Leong, Jia Lian Chee, Amalia Karahalios, Annabelle Skelley, Kim Wong
Malnutrition is common in patients on hemodialysis (prevalence of 30% to 50%) and is associated with higher mortality. Lean body mass (LBM) assessment is an accurate way of assessing nutritional status. The dual-energy X-ray absorptiometry (DEXA) scan is a reliable method in assessing body compositions and LBM; however, it is expensive and largely inaccessible. Anthropometric skinfold thickness measurement (ASFM) is useful in assessing LBM. It is cheaper and accessible, but underutilized clinically. The subjective global score (SGA) is a well-established method of assessing nutritional status...
January 2018: Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association
https://www.readbyqxmd.com/read/29469787/telangiectasia-macularis-eruptiva-perstans-associated-with-a-sicca-complex
#16
Ramone Faith Williams, Rosalynn M Nazarian, Gideon P Smith
We present the case of woman in her 50s who developed numerous red-brown telangiectatic macules on her trunk and extremities, as well as persistent dry eyes and dry mouth. Skin biopsy was consistent with telangiectasia macularis eruptiva perstans (TMEP). Serum tryptase was elevated suggesting systemic involvement. Anti-Ro and La were negative. ANA was positive. Salivary gland biopsy revealed a focus score of 3 and immunostains revealed infiltrates of aberrant CD117 positive mast cells. This case suggests a mechanistic role of mastocytosis in salivary compromise...
October 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29469593/l-carnosine-as-adjunctive-therapy-in-children-and-adolescents-with-attention-deficit-hyperactivity-disorder-a-randomized-double-blind-placebo-controlled-clinical-trial
#17
Alireza Ghajar, Farinaz Aghajan-Nashtaei, Mohsen Afarideh, Mohammad-Reza Mohammadi, Shahin Akhondzadeh
OBJECTIVES: This study aimed to investigate the efficacy and tolerability of l-carnosine as an add-on to methylphenidate in management of children with attention-deficit/hyperactivity disorder (ADHD). METHODS: This was an 8-week, randomized, double-blind placebo-controlled study. Fifty-six drug-free children and adolescents aged 6-17 years old with a diagnosis of ADHD entered the study. The patients were randomly assigned to l-carnosine (800 mg/d in two divided doses) or placebo plus methylphenidate (0...
February 22, 2018: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29469320/-investigation-on-malaria-knowledge-and-demands-on-related-training-for-cdc-staff-in-qinghai-province-china
#18
Zhang Shao-Sen, Cai Hui-Xia, Tu Hong, Yan He, Liu Na, Ma Jun-Ying
OBJECTIVE: To investigate the malaria knowledge of CDC staff and their demands on related training in malaria non-endemic areas, so as to provide the reference for planning the appropriate curriculum. METHODS: All the participants who were the staff of county CDCs all over Qinghai Province and attended the provincial training workshop were surveyed. A self-administered questionnaire survey was carried out and the data was statistically analyzed. RESULTS: A total of 115 participants were involved in this survey...
April 7, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29469076/quality-of-life-outcome-measures-using-university-of-washington-questionnaire-version-4-in-early-t1-t2-anterior-tongue-cancers-with-and-without-radiotherapy-a-cross-sectional-study
#19
P Sakthivel, D V K Irugu, C A Singh, H Verma, R Yogal, B Jat, A Chadran, K Sikka, A Thakar, S C Sharma
CONTEXT: To evaluate the quality of life (QOL) outcome measures in disease-free survivors of pathological T1/T2 tongue cancers and to compare QOL in patients treated with only surgery and with adjuvant treatment. SETTINGS AND DESIGN: Cross-sectional survey. PATIENTS AND METHODS: All pathological T1/T2 anterior tongue cancer cases with follow-up from January 2011 till December 2015, who had locoregionally controlled disease with a minimum disease-free survival period of 1 year, were included in the study...
April 2017: Indian Journal of Cancer
https://www.readbyqxmd.com/read/29469029/preclinical-evaluation-of-degradation-kinetics-and-elemental-mapping-of-first-and-second-generation-bioresorbable-magnesium-scaffolds
#20
Michael Joner, Philipp Ruppelt, Philine Zumstein, Capucine Lapointe-Corriveau, Guy Leclerc, Anna Bulin, Maria Isabel Castellanos, Eric Wittchow, Michael Haude, Ron Waksman
AIMS: Because vascular restoration therapy using bioresorbable vascular scaffolds (BRS) remains an appealing concept to restore vasoreactivity, understanding of biodegradation remains paramount during preclinical testing. METHODS AND RESULTS: Qualitative characterization of biodegradation was performed in 41 DREAMS 1G up to 3 years, while degradation kinetics were acquired in 54 DREAMS 2G implanted into porcine coronary arteries for 28, 90 and 180 days, 1 and 2 years...
February 20, 2018: EuroIntervention
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